Search of human proteins with 28416431

Search of human proteins with 28416431

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28416431 GTPase, IMAP family member 2 [Homo sapiens]
         (337 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28416431 GTPase, IMAP family member 2 [Homo sapiens]               690   0.0  
gi|18594498 GTPase, IMAP family member 1 [Homo sapiens]               224   8e-59
gi|28416949 GTPase, IMAP family member 5 [Homo sapiens]               222   3e-58
gi|56119214 GTPase, IMAP family member 6 [Homo sapiens]               201   1e-51
gi|23397516 GTPase, IMAP family member 7 [Homo sapiens]               182   5e-46
gi|8922873 GTPase, IMAP family member 4 [Homo sapiens]                170   1e-42
gi|28416956 GTPase, IMAP family member 8 [Homo sapiens]               165   5e-41
gi|239753874 PREDICTED: similar to hCG2036814 [Homo sapiens]           32   1.1  
gi|239748437 PREDICTED: similar to hCG2036814 [Homo sapiens]           32   1.1  
gi|239742371 PREDICTED: hypothetical protein XP_002342504 [Homo ...    32   1.1  
gi|24307899 Era-like 1 [Homo sapiens]                                  31   1.8  
gi|45269137 mitofusin 1 [Homo sapiens]                                 30   2.3  
gi|166706909 interferon-induced protein 44-like [Homo sapiens]         30   2.3  
gi|71043966 endonuclease/exonuclease/phosphatase family domain c...    30   3.1  
gi|37622910 cholinergic receptor, muscarinic 1 [Homo sapiens]          30   4.0  
gi|4506371 RAB5B, member RAS oncogene family [Homo sapiens]            29   5.2  
gi|194294521 intersectin 2 isoform 1 [Homo sapiens]                    29   5.2  
gi|194294525 intersectin 2 isoform 2 [Homo sapiens]                    29   5.2  
gi|148664201 cytoskeleton associated protein 2 isoform 2 [Homo s...    29   5.2  
gi|148664244 cytoskeleton associated protein 2 isoform 1 [Homo s...    29   5.2  
gi|30089952 protein tyrosine phosphatase domain containing 1 pro...    29   5.2  
gi|30089950 protein tyrosine phosphatase domain containing 1 pro...    29   5.2  

>gi|28416431 GTPase, IMAP family member 2 [Homo sapiens]
          Length = 337

 Score =  690 bits (1780), Expect = 0.0
 Identities = 337/337 (100%), Positives = 337/337 (100%)

Query: 1   MDQNEHSHWGPHAKGQCASRSELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKT 60
           MDQNEHSHWGPHAKGQCASRSELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKT
Sbjct: 1   MDQNEHSHWGPHAKGQCASRSELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKT 60

Query: 61  CSKSQGSWGNREIVIIDTPDMFSWKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYTS 120
           CSKSQGSWGNREIVIIDTPDMFSWKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYTS
Sbjct: 61  CSKSQGSWGNREIVIIDTPDMFSWKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYTS 120

Query: 121 QDQQAAQRVKEIFGEDAMGHTIVLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRIC 180
           QDQQAAQRVKEIFGEDAMGHTIVLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRIC
Sbjct: 121 QDQQAAQRVKEIFGEDAMGHTIVLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRIC 180

Query: 181 AFNNRAEGSNQDDQVKELMDCIEDLLMEKNGDHYTNGLYSLIQRSKCGPVGSDERVKEFK 240
           AFNNRAEGSNQDDQVKELMDCIEDLLMEKNGDHYTNGLYSLIQRSKCGPVGSDERVKEFK
Sbjct: 181 AFNNRAEGSNQDDQVKELMDCIEDLLMEKNGDHYTNGLYSLIQRSKCGPVGSDERVKEFK 240

Query: 241 QSLIKYMETQRSYTALAEANCLKGALIKTQLCVLFCIQLFLRLIILWLCILHSMCNLFCC 300
           QSLIKYMETQRSYTALAEANCLKGALIKTQLCVLFCIQLFLRLIILWLCILHSMCNLFCC
Sbjct: 241 QSLIKYMETQRSYTALAEANCLKGALIKTQLCVLFCIQLFLRLIILWLCILHSMCNLFCC 300

Query: 301 LLFSMCNLFCSLLFIIPKKLMIFLRTVIRLERKTPRL 337
           LLFSMCNLFCSLLFIIPKKLMIFLRTVIRLERKTPRL
Sbjct: 301 LLFSMCNLFCSLLFIIPKKLMIFLRTVIRLERKTPRL 337


>gi|18594498 GTPase, IMAP family member 1 [Homo sapiens]
          Length = 306

 Score =  224 bits (571), Expect = 8e-59
 Identities = 123/283 (43%), Positives = 178/283 (62%), Gaps = 17/283 (6%)

Query: 1   MDQNEHSHWGPHAKGQCASRSELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKT 60
           M  +E + +G     Q    S  R+ILVG+TG GKSA GNSIL ++ F S+LG+ ++T+ 
Sbjct: 6   MATDEENVYGLEENAQSRQESTRRLILVGRTGAGKSATGNSILGQRRFFSRLGATSVTRA 65

Query: 61  CSKSQGSWGNREIVIIDTPDMFSWK-DHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYT 119
           C+     W    + ++DTPD+FS +    +   +E   CYLLSAPGPH LLLVTQLGR+T
Sbjct: 66  CTTGSRRWDKCHVEVVDTPDIFSSQVSKTDPGCEERGHCYLLSAPGPHALLLVTQLGRFT 125

Query: 120 SQDQQAAQRVKEIFGEDAMGHTIVLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRI 179
           +QDQQA ++V+++FGED +   +++FT KEDL GGSL DY+ +++N+AL +LVA CGGR+
Sbjct: 126 AQDQQAVRQVRDMFGEDVLKWMVIVFTRKEDLAGGSLHDYVSNTENRALRELVAECGGRV 185

Query: 180 CAFNNRAEGSNQDDQVKELMDCIEDLLMEKNGDHYTNGLYSLIQRSK-CGPVGSDERVKE 238
           CAF+NRA G  Q+ QV++L+  +E L++E  G HY+N +Y L Q  +  GP     RV E
Sbjct: 186 CAFDNRATGREQEAQVEQLLGMVEGLVLEHKGAHYSNEVYELAQVLRWAGPEERLRRVAE 245

Query: 239 --------------FKQSLIKYMETQRSYTALAEANCLKGALI 267
                             L K++++ RS+  L  A  L GAL+
Sbjct: 246 RVAARVQRRPWGAWLSARLWKWLKSPRSW-RLGLALLLGGALL 287


>gi|28416949 GTPase, IMAP family member 5 [Homo sapiens]
          Length = 307

 Score =  222 bits (566), Expect = 3e-58
 Identities = 126/303 (41%), Positives = 182/303 (60%), Gaps = 17/303 (5%)

Query: 5   EHSHWGPHAKGQC-----ASRSELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTK 59
           +   +G  A+G+      A+   LRIILVGKTG GKSA GNSIL +  FESKL +Q++T+
Sbjct: 5   QRGKYGTMAEGRSEDNLSATPPALRIILVGKTGCGKSATGNSILGQPVFESKLRAQSVTR 64

Query: 60  TCSKSQGSWGNREIVIIDTPDMFSWKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYT 119
           TC    G+W  R+++++DTP +F  +   + LYK +  CYLLSAPGPHVLLLV QLGR+T
Sbjct: 65  TCQVKTGTWNGRKVLVVDTPSIFESQADTQELYKNIGDCYLLSAPGPHVLLLVIQLGRFT 124

Query: 120 SQDQQAAQRVKEIFGEDAMGHTIVLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRI 179
           +QD  A ++VKE+FG  AM H ++LFTHKEDL G +L DY+ ++DN +L  LV  C  R 
Sbjct: 125 AQDTVAIRKVKEVFGTGAMRHVVILFTHKEDLGGQALDDYVANTDNCSLKDLVRECERRY 184

Query: 180 CAFNNRAEGSNQDDQVKELMDCIEDLLMEKNGDHYTNGLY---SLIQRSKCGPVGSDERV 236
           CAFNN      Q  Q  EL+  IE L  E+ G  ++N L+    L+QR+  G    D R 
Sbjct: 185 CAFNNWGSVEEQRQQQAELLAVIERLGREREGSFHSNDLFLDAQLLQRTGAGACQEDYR- 243

Query: 237 KEFKQSLIKYMETQRSYTALAEANCLKGALIKTQLCVLFCIQLFLRLI-------ILWLC 289
            +++  +   +E  +      E+N    AL++ +  +L   ++F+ L+       I++L 
Sbjct: 244 -QYQAKVEWQVEKHKQELRENESNWAYKALLRVKHLMLLHYEIFVFLLLCSILFFIIFLF 302

Query: 290 ILH 292
           I H
Sbjct: 303 IFH 305


>gi|56119214 GTPase, IMAP family member 6 [Homo sapiens]
          Length = 292

 Score =  201 bits (510), Expect = 1e-51
 Identities = 97/203 (47%), Positives = 142/203 (69%), Gaps = 1/203 (0%)

Query: 23  LRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCSKSQGSWGNREIVIIDTPDMF 82
           LR+IL+GKTG+GKSA GNSIL +  FESKL ++ +TKT  +    W  +E+ +IDTP++ 
Sbjct: 41  LRLILMGKTGSGKSATGNSILGRDVFESKLSTRPVTKTSQRRSREWAGKELEVIDTPNIL 100

Query: 83  SWKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYTSQDQQAAQRVKEIFGEDAMGHTI 142
           S +   E     + +  +LSAPGPH +LLVTQLGR+T +DQQ  +R++E+FG   +GHTI
Sbjct: 101 SPQVSPEVA-DAICQAIVLSAPGPHAVLLVTQLGRFTDEDQQVVRRLQEVFGVGVLGHTI 159

Query: 143 VLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRICAFNNRAEGSNQDDQVKELMDCI 202
           ++FT KEDL GGSL DY+ +++N+AL+ L      R C FNNRA+G  Q+ Q++ELM+ +
Sbjct: 160 LVFTRKEDLAGGSLEDYVRETNNQALAWLDVTLARRHCGFNNRAQGEEQEAQLRELMEKV 219

Query: 203 EDLLMEKNGDHYTNGLYSLIQRS 225
           E ++ E  GD+Y+N  Y   Q++
Sbjct: 220 EAIMWENEGDYYSNKAYQYTQQN 242


>gi|23397516 GTPase, IMAP family member 7 [Homo sapiens]
          Length = 300

 Score =  182 bits (461), Expect = 5e-46
 Identities = 87/230 (37%), Positives = 144/230 (62%), Gaps = 13/230 (5%)

Query: 23  LRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCSKSQGSWGNREIVIIDTPDMF 82
           LRI+LVGKTG+GKSA  N+IL ++ F+S++ +Q +TK C K+   W  R+++++DTP +F
Sbjct: 9   LRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASREWQGRDLLVVDTPGLF 68

Query: 83  SWKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYTSQDQQAAQRVKEIFGEDAMGHTI 142
             K+  +   KE+ RC + S PGPH ++LV  LGRYT ++Q+    +K +FG+ AM H +
Sbjct: 69  DTKESLDTTCKEISRCIISSCPGPHAIVLVLLLGRYTEEEQKTVALIKAVFGKSAMKHMV 128

Query: 143 VLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRICAFNN--RAEGSNQDDQVKELMD 200
           +LFT KE+L G S  D++ D+D   L  +V  CG R CAF+N  +   + ++ QV+EL++
Sbjct: 129 ILFTRKEELEGQSFHDFIADAD-VGLKSIVKECGNRCCAFSNSKKTSKAEKESQVQELVE 187

Query: 201 CIEDLLMEKNGDHYTNGLYSLIQRSKCGPVGSDERVKEFKQSLIKYMETQ 250
            IE ++    G ++++ +Y            ++ER+K+ ++ L K    Q
Sbjct: 188 LIEKMVQCNEGAYFSDDIYK----------DTEERLKQREEVLRKIYTDQ 227


>gi|8922873 GTPase, IMAP family member 4 [Homo sapiens]
          Length = 329

 Score =  170 bits (431), Expect = 1e-42
 Identities = 84/199 (42%), Positives = 127/199 (63%), Gaps = 1/199 (0%)

Query: 21  SELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCSKSQGSWGNREIVIIDTPD 80
           S+LRI+LVGKTG GKSA GNSIL ++ F S   ++++TK C K   SW   E+V++DTP 
Sbjct: 29  SQLRIVLVGKTGAGKSATGNSILGRKVFHSGTAAKSITKKCEKRSSSWKETELVVVDTPG 88

Query: 81  MFSWKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYTSQDQQAAQRVKEIFGEDAMGH 140
           +F  +       KE+ RC LL++PGPH LLLV  LGRYT ++ +A +++ ++FGE A   
Sbjct: 89  IFDTEVPNAETSKEIIRCILLTSPGPHALLLVVPLGRYTEEEHKATEKILKMFGERARSF 148

Query: 141 TIVLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRICAFNNRAEGSNQDDQVKELMD 200
            I++FT K+DL   +L DY+ ++  + +  L+   G R CA NN+A G+ Q+ Q  +L+ 
Sbjct: 149 MILIFTRKDDLGDTNLHDYLREAP-EDIQDLMDIFGDRYCALNNKATGAEQEAQRAQLLG 207

Query: 201 CIEDLLMEKNGDHYTNGLY 219
            I+ ++ E     YTN +Y
Sbjct: 208 LIQRVVRENKEGCYTNRMY 226


>gi|28416956 GTPase, IMAP family member 8 [Homo sapiens]
          Length = 665

 Score =  165 bits (418), Expect = 5e-41
 Identities = 85/198 (42%), Positives = 120/198 (60%), Gaps = 3/198 (1%)

Query: 20  RSELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCSKSQGSWGNREIVIIDTP 79
           +  L I+LVG++GTGKSA GNSIL    F S+L +Q +TKT    + +W  +E+V++DTP
Sbjct: 436 KETLNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQPVTKTSQSGRRTWDGQEVVVVDTP 495

Query: 80  D---MFSWKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYTSQDQQAAQRVKEIFGED 136
               M   +     L +EV+RC      G    +LV QLGR+T +D+ A  +++ IFG D
Sbjct: 496 SFNQMLDVEKDPSRLEEEVKRCLSCCEKGDTFFVLVFQLGRFTEEDKTAVAKLEAIFGAD 555

Query: 137 AMGHTIVLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRICAFNNRAEGSNQDDQVK 196
              + I+LFT KEDL  G+L D+M +SDNKAL ++   CG R+CAFNN+  G  Q+ QVK
Sbjct: 556 FTKYAIMLFTRKEDLGAGNLEDFMKNSDNKALRRIFKKCGRRVCAFNNKETGQAQETQVK 615

Query: 197 ELMDCIEDLLMEKNGDHY 214
            L+  + DL  E     Y
Sbjct: 616 ALLTKVNDLRKESGWSGY 633



 Score =  153 bits (387), Expect = 2e-37
 Identities = 81/202 (40%), Positives = 119/202 (58%), Gaps = 3/202 (1%)

Query: 16  QCASRSELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCSKSQGSWGNREIVI 75
           Q    SELR++L+GK  +GKSA GN+IL K  F+SK   QT+ K C +       R++V+
Sbjct: 4   QSCQMSELRLLLLGKCRSGKSATGNAILGKHVFKSKFSDQTVIKMCQRESWVLRERKVVV 63

Query: 76  IDTPDMFSWKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYTSQDQQAAQRVKEIFGE 135
           IDTPD+FS     E   + +Q C  LSAP  H LLLV  +G +T +D++ A+ ++++FG 
Sbjct: 64  IDTPDLFSSIACAEDKQRNIQHCLELSAPSLHALLLVIAIGHFTREDEETAKGIQQVFGA 123

Query: 136 DAMGHTIVLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRICAFNNRAEGSN-QDDQ 194
           +A  H I++FT K+DL    L D++    NK L +LV    GR C FNN+    + Q  Q
Sbjct: 124 EARRHIIIVFTRKDDLGDDLLQDFI--EKNKPLKQLVQDYEGRYCIFNNKTNSKDEQITQ 181

Query: 195 VKELMDCIEDLLMEKNGDHYTN 216
           V EL+  +E L+    G ++ N
Sbjct: 182 VLELLRKVESLVNTNGGPYHVN 203



 Score =  135 bits (341), Expect = 4e-32
 Identities = 76/193 (39%), Positives = 107/193 (55%), Gaps = 8/193 (4%)

Query: 21  SELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCSKSQGSWGNREIVIIDTPD 80
           SEL ++LVGK G GKSAAGNSIL +QAF++    Q++T++      SW  +++ IID PD
Sbjct: 246 SELTVLLVGKRGAGKSAAGNSILGRQAFQTGFSEQSVTQSFLSESRSWRKKKVSIIDAPD 305

Query: 81  MFSWKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYTSQDQQAAQRVKEIFGEDAMGH 140
           + S K+    + K +         GPH  LLVT LG YT  D+     ++  FGE    +
Sbjct: 306 ISSLKNIDSEVRKHI-------CTGPHAFLLVTPLGFYTKNDEAVLSTIQNNFGEKFFEY 358

Query: 141 TIVLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRICAFNNRAEGSNQDDQVKELMD 200
            I+L T KEDL    L  ++ +S NKAL  L+  C  R  AFN RA G  +  Q  EL++
Sbjct: 359 MIILLTRKEDLGDQDLDTFLRNS-NKALYGLIQKCKNRYSAFNYRATGEEEQRQADELLE 417

Query: 201 CIEDLLMEKNGDH 213
            IE ++ +    H
Sbjct: 418 KIESMVHQNGNKH 430


>gi|239753874 PREDICTED: similar to hCG2036814 [Homo sapiens]
          Length = 547

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 15/40 (37%), Positives = 22/40 (55%)

Query: 23  LRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCS 62
           + + L G T +GKS+AGN +L    F S     ++T  CS
Sbjct: 284 INLALFGMTQSGKSSAGNILLGSTDFHSSFAPCSVTTCCS 323



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 14/44 (31%), Positives = 24/44 (54%), Gaps = 2/44 (4%)

Query: 124 QAAQRVKEIFGEDAMGHTIVLFTHKEDLNGGSLMD--YMHDSDN 165
           Q   + KE+ G   M +T +LFTH E +    L +  Y+H++ +
Sbjct: 455 QFLSQFKELLGHAWMNYTAILFTHAEKIEEAGLTEDKYLHEASD 498


>gi|239748437 PREDICTED: similar to hCG2036814 [Homo sapiens]
          Length = 547

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 15/40 (37%), Positives = 22/40 (55%)

Query: 23  LRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCS 62
           + + L G T +GKS+AGN +L    F S     ++T  CS
Sbjct: 284 INLALFGMTQSGKSSAGNILLGSTDFHSSFAPCSVTTCCS 323



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 14/44 (31%), Positives = 24/44 (54%), Gaps = 2/44 (4%)

Query: 124 QAAQRVKEIFGEDAMGHTIVLFTHKEDLNGGSLMD--YMHDSDN 165
           Q   + KE+ G   M +T +LFTH E +    L +  Y+H++ +
Sbjct: 455 QFLSQFKELLGHAWMNYTAILFTHAEKIEEAGLTEDKYLHEASD 498


>gi|239742371 PREDICTED: hypothetical protein XP_002342504 [Homo
           sapiens]
          Length = 547

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 15/40 (37%), Positives = 22/40 (55%)

Query: 23  LRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCS 62
           + + L G T +GKS+AGN +L    F S     ++T  CS
Sbjct: 284 INLALFGMTQSGKSSAGNILLGSTDFHSSFAPCSVTTCCS 323



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 14/44 (31%), Positives = 24/44 (54%), Gaps = 2/44 (4%)

Query: 124 QAAQRVKEIFGEDAMGHTIVLFTHKEDLNGGSLMD--YMHDSDN 165
           Q   + KE+ G   M +T +LFTH E +    L +  Y+H++ +
Sbjct: 455 QFLSQFKELLGHAWMNYTAILFTHAEKIEEAGLTEDKYLHEASD 498


>gi|24307899 Era-like 1 [Homo sapiens]
          Length = 437

 Score = 30.8 bits (68), Expect = 1.8
 Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 5/63 (7%)

Query: 23  LRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCSKSQGSWGNRE--IVIIDTPD 80
           LR++L+G    GKS   N +L ++ F     S+ +  T  ++ G    +E  ++++DTP 
Sbjct: 114 LRVVLLGAPNAGKSTLSNQLLGRKVFPV---SRKVHTTRCQALGVITEKETQVILLDTPG 170

Query: 81  MFS 83
           + S
Sbjct: 171 IIS 173


>gi|45269137 mitofusin 1 [Homo sapiens]
          Length = 741

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 16/66 (24%), Positives = 35/66 (53%), Gaps = 2/66 (3%)

Query: 15  GQCASRSELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCSKSQGSWGNREIV 74
           G+  SR  +++   G+T +GKS+  N++L  +   S +G   +T      +G+ G++  +
Sbjct: 68  GEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGH--ITNCFLSVEGTDGDKAYL 125

Query: 75  IIDTPD 80
           + +  D
Sbjct: 126 MTEGSD 131


>gi|166706909 interferon-induced protein 44-like [Homo sapiens]
          Length = 452

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 16/37 (43%), Positives = 23/37 (62%), Gaps = 2/37 (5%)

Query: 21  SELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTL 57
           SE+RI+LVG  G+GKS+  NS+  K  F   +  Q +
Sbjct: 196 SEIRILLVGPVGSGKSSFFNSV--KSIFHGHVTGQAV 230


>gi|71043966 endonuclease/exonuclease/phosphatase family domain
           containing 1 [Homo sapiens]
          Length = 569

 Score = 30.0 bits (66), Expect = 3.1
 Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 26/98 (26%)

Query: 20  RSELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCSKS-QGS------WGNRE 72
           + E  +I++G  G G  +    ILRK+ F   + + T T   +K+ QGS      W ++ 
Sbjct: 438 KGEKDVIILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNISTKNPQGSKSLDNIWISKS 497

Query: 73  IVIIDT---------------PDMFSW----KDHCEAL 91
           +  + T               PD +SW     +HC  L
Sbjct: 498 LKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPVL 535


>gi|37622910 cholinergic receptor, muscarinic 1 [Homo sapiens]
          Length = 460

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 28/112 (25%), Positives = 45/112 (40%), Gaps = 11/112 (9%)

Query: 229 PVGSDERVKEFKQSLIKYMETQRSYTALAEANCLKGALIKTQLCVLF----CIQLFLRLI 284
           P G ++  K    SL+K  +  R+ +A+  A  L        + V      C+   L  +
Sbjct: 343 PRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWEL 402

Query: 285 ILWLCILHSMCNLFCCLLFSMCNLFCSLLFIIPKKLMIFLRTVIRLERKTPR 336
             WLC ++S  N        MC   C+  F    +L++  R   R  RK P+
Sbjct: 403 GYWLCYVNSTIN-------PMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPK 447


>gi|4506371 RAB5B, member RAS oncogene family [Homo sapiens]
          Length = 215

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 32/153 (20%), Positives = 64/153 (41%), Gaps = 20/153 (13%)

Query: 11  PHAKGQCASRSELRIILVGKTGTGKSAAGNSILRKQAF---ESKLGSQTLTKTCSKSQGS 67
           P+ + Q +   + +++L+G++  GKS+     ++ Q     ES +G+  LT++       
Sbjct: 9   PNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQS------- 61

Query: 68  WGNREIVIIDTPDMFS-WKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYTSQDQQAA 126
                + + DT   F  W    +  Y  +   Y   A    V+  +T    +     +A 
Sbjct: 62  -----VCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFA----RAK 112

Query: 127 QRVKEIFGEDAMGHTIVLFTHKEDLNGGSLMDY 159
             VKE+  + +    I L  +K DL    +++Y
Sbjct: 113 TWVKELQRQASPSIVIALAGNKADLANKRMVEY 145


>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
          Length = 1697

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 27/115 (23%), Positives = 55/115 (47%), Gaps = 11/115 (9%)

Query: 143 VLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRICAFNNRAEGSNQDDQVKE----L 198
           V   HK+ L    L   + +  + AL K  A+    + +FNN+ +  N DD V +    L
Sbjct: 578 VSLLHKKSLEKEELCQRLKEQLD-ALEKETASKLSEMDSFNNQLKCGNMDDSVLQCLLSL 636

Query: 199 MDCIED--LLMEKNGDHYTNGLYSLIQRSKCGPVGSDERVKEFKQSLIKYMETQR 251
           + C+ +  LL+++  + Y     +L Q  K       +++KE ++  ++ M+ ++
Sbjct: 637 LSCLNNLFLLLKELRETYNTQQLALEQLYKI----KRDKLKEIERKRLELMQKKK 687


>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
          Length = 1249

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 27/115 (23%), Positives = 55/115 (47%), Gaps = 11/115 (9%)

Query: 143 VLFTHKEDLNGGSLMDYMHDSDNKALSKLVAACGGRICAFNNRAEGSNQDDQVKE----L 198
           V   HK+ L    L   + +  + AL K  A+    + +FNN+ +  N DD V +    L
Sbjct: 578 VSLLHKKSLEKEELCQRLKEQLD-ALEKETASKLSEMDSFNNQLKCGNMDDSVLQCLLSL 636

Query: 199 MDCIED--LLMEKNGDHYTNGLYSLIQRSKCGPVGSDERVKEFKQSLIKYMETQR 251
           + C+ +  LL+++  + Y     +L Q  K       +++KE ++  ++ M+ ++
Sbjct: 637 LSCLNNLFLLLKELRETYNTQQLALEQLYKI----KRDKLKEIERKRLELMQKKK 687


>gi|148664201 cytoskeleton associated protein 2 isoform 2 [Homo
           sapiens]
          Length = 683

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 6/65 (9%)

Query: 1   MDQNEHSHWGPHAKGQCASRSELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKT 60
           M   E ++ G + +  CAS+ E++ + +  TG            K   ESKL    L + 
Sbjct: 508 MKSQEKANLGENMEKSCASKEEVKEVSIEDTGVDVDP------EKLEMESKLHRNLLFQD 561

Query: 61  CSKSQ 65
           C K Q
Sbjct: 562 CEKEQ 566


>gi|148664244 cytoskeleton associated protein 2 isoform 1 [Homo
           sapiens]
          Length = 682

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 6/65 (9%)

Query: 1   MDQNEHSHWGPHAKGQCASRSELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKT 60
           M   E ++ G + +  CAS+ E++ + +  TG            K   ESKL    L + 
Sbjct: 507 MKSQEKANLGENMEKSCASKEEVKEVSIEDTGVDVDP------EKLEMESKLHRNLLFQD 560

Query: 61  CSKSQ 65
           C K Q
Sbjct: 561 CEKEQ 565


>gi|30089952 protein tyrosine phosphatase domain containing 1
           protein isoform 1 [Homo sapiens]
          Length = 806

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 11/23 (47%), Positives = 14/23 (60%)

Query: 174 ACGGRICAFNNRAEGSNQDDQVK 196
           ACGGR C + N A  S Q+  +K
Sbjct: 109 ACGGRACKYENPARWSEQEQAIK 131


>gi|30089950 protein tyrosine phosphatase domain containing 1
           protein isoform 2 [Homo sapiens]
          Length = 754

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 11/23 (47%), Positives = 14/23 (60%)

Query: 174 ACGGRICAFNNRAEGSNQDDQVK 196
           ACGGR C + N A  S Q+  +K
Sbjct: 57  ACGGRACKYENPARWSEQEQAIK 79


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.137    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,845,524
Number of Sequences: 37866
Number of extensions: 544771
Number of successful extensions: 1874
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1845
Number of HSP's gapped (non-prelim): 27
length of query: 337
length of database: 18,247,518
effective HSP length: 103
effective length of query: 234
effective length of database: 14,347,320
effective search space: 3357272880
effective search space used: 3357272880
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.