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Search of human proteins with 27894378
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27894378 chloride intracellular channel 6 [Homo sapiens]
(686 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27894378 chloride intracellular channel 6 [Homo sapiens] 1382 0.0
gi|7330335 chloride intracellular channel 4 [Homo sapiens] 382 e-106
gi|82617632 chloride intracellular channel 5 isoform b [Homo sap... 370 e-102
gi|166197662 chloride intracellular channel 5 isoform a [Homo sa... 369 e-102
gi|66346733 chloride intracellular channel 2 [Homo sapiens] 330 3e-90
gi|14251209 chloride intracellular channel 1 [Homo sapiens] 313 3e-85
gi|40288290 chloride intracellular channel 3 [Homo sapiens] 226 5e-59
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 122 1e-27
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 112 9e-25
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 99 2e-20
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 99 2e-20
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 98 3e-20
gi|48762934 alpha 2 type I collagen [Homo sapiens] 95 2e-19
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 91 5e-18
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 89 1e-17
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 89 1e-17
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 89 1e-17
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 89 1e-17
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 88 2e-17
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 87 7e-17
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 84 3e-16
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 82 1e-15
gi|154759255 collagen, type XXVIII precursor [Homo sapiens] 82 2e-15
gi|11386161 alpha 2 type IX collagen [Homo sapiens] 81 3e-15
gi|22027593 alpha 1 type XIII collagen isoform 11 [Homo sapiens] 80 6e-15
gi|22027587 alpha 1 type XIII collagen isoform 8 [Homo sapiens] 80 6e-15
gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens] 80 8e-15
gi|119508426 alpha 3 type IX collagen [Homo sapiens] 79 1e-14
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 78 3e-14
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 78 3e-14
>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
Length = 686
Score = 1382 bits (3577), Expect = 0.0
Identities = 686/686 (100%), Positives = 686/686 (100%)
Query: 1 MAEAAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEA 60
MAEAAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEA
Sbjct: 1 MAEAAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEA 60
Query: 61 GGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGE 120
GGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGE
Sbjct: 61 GGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGE 120
Query: 121 PRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSV 180
PRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSV
Sbjct: 121 PRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSV 180
Query: 181 EAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSV 240
EAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSV
Sbjct: 181 EAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSV 240
Query: 241 DAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSG 300
DAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSG
Sbjct: 241 DAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSG 300
Query: 301 DGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVG 360
DGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVG
Sbjct: 301 DGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVG 360
Query: 361 DGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEE 420
DGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEE
Sbjct: 361 DGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEE 420
Query: 421 GPAEGSGEAARVNGRREDGEASEPRALGQEHDITLFVKAGYDGESIGNCPFSQRLFMILW 480
GPAEGSGEAARVNGRREDGEASEPRALGQEHDITLFVKAGYDGESIGNCPFSQRLFMILW
Sbjct: 421 GPAEGSGEAARVNGRREDGEASEPRALGQEHDITLFVKAGYDGESIGNCPFSQRLFMILW 480
Query: 481 LKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLAPPRYPK 540
LKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLAPPRYPK
Sbjct: 481 LKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLAPPRYPK 540
Query: 541 LGTQHPESNSAGNDVFAKFSAFIKNTKKDANEIHEKNLLKALRKLDNYLNSPLPDEIDAY 600
LGTQHPESNSAGNDVFAKFSAFIKNTKKDANEIHEKNLLKALRKLDNYLNSPLPDEIDAY
Sbjct: 541 LGTQHPESNSAGNDVFAKFSAFIKNTKKDANEIHEKNLLKALRKLDNYLNSPLPDEIDAY 600
Query: 601 STEDVTVSGRKFLDGDELTLADCNLLPKLHIIKIVAKKYRDFEFPSEMTGIWRYLNNAYA 660
STEDVTVSGRKFLDGDELTLADCNLLPKLHIIKIVAKKYRDFEFPSEMTGIWRYLNNAYA
Sbjct: 601 STEDVTVSGRKFLDGDELTLADCNLLPKLHIIKIVAKKYRDFEFPSEMTGIWRYLNNAYA 660
Query: 661 RDEFTNTCPADQEIEHAYSDVAKRMK 686
RDEFTNTCPADQEIEHAYSDVAKRMK
Sbjct: 661 RDEFTNTCPADQEIEHAYSDVAKRMK 686
>gi|7330335 chloride intracellular channel 4 [Homo sapiens]
Length = 253
Score = 382 bits (980), Expect = e-106
Identities = 181/233 (77%), Positives = 208/233 (89%)
Query: 453 ITLFVKAGYDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFM 512
I LFVKAG DGESIGNCPFSQRLFMILWLKGV+F+VTTVDLKRKPADLQNLAPGT+PPF+
Sbjct: 19 IELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFI 78
Query: 513 TFDGEVKTDVNKIEEFLEEKLAPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKKDANE 572
TF+ EVKTDVNKIEEFLEE L PP+Y KL +HPESN+AG D+FAKFSA+IKN++ +ANE
Sbjct: 79 TFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANE 138
Query: 573 IHEKNLLKALRKLDNYLNSPLPDEIDAYSTEDVTVSGRKFLDGDELTLADCNLLPKLHII 632
E+ LLK L+KLD YLNSPLPDEID S ED+ S RKFLDG+E+TLADCNLLPKLHI+
Sbjct: 139 ALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRKFLDGNEMTLADCNLLPKLHIV 198
Query: 633 KIVAKKYRDFEFPSEMTGIWRYLNNAYARDEFTNTCPADQEIEHAYSDVAKRM 685
K+VAKKYR+F+ P EMTGIWRYL NAY+RDEFTNTCP+D+E+E AYSDVAKR+
Sbjct: 199 KVVAKKYRNFDIPKEMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVAKRL 251
>gi|82617632 chloride intracellular channel 5 isoform b [Homo
sapiens]
Length = 251
Score = 370 bits (949), Expect = e-102
Identities = 176/237 (74%), Positives = 207/237 (87%)
Query: 449 QEHDITLFVKAGYDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTN 508
++ +I LFVKAG DGESIGNCPFSQRLFMILWLKGV+FNVTTVDLKRKPADL NLAPGT+
Sbjct: 12 RDPEIELFVKAGIDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLKRKPADLHNLAPGTH 71
Query: 509 PPFMTFDGEVKTDVNKIEEFLEEKLAPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKK 568
PPF+TF+G+VKTDVNKIEEFLEE L P +YPKL +H ESN+AG D+F+KFSA+IKNTK+
Sbjct: 72 PPFLTFNGDVKTDVNKIEEFLEETLTPEKYPKLAAKHRESNTAGIDIFSKFSAYIKNTKQ 131
Query: 569 DANEIHEKNLLKALRKLDNYLNSPLPDEIDAYSTEDVTVSGRKFLDGDELTLADCNLLPK 628
N E+ L KAL+KLD+YLN+PLP+EIDA + + S RKFLDGDELTLADCNLLPK
Sbjct: 132 QNNAALERGLTKALKKLDDYLNTPLPEEIDANTCGEDKGSRRKFLDGDELTLADCNLLPK 191
Query: 629 LHIIKIVAKKYRDFEFPSEMTGIWRYLNNAYARDEFTNTCPADQEIEHAYSDVAKRM 685
LH++KIVAKKYR+++ P+EMTG+WRYL NAYARDEFTNTC AD EIE AY+DVAKR+
Sbjct: 192 LHVVKIVAKKYRNYDIPAEMTGLWRYLKNAYARDEFTNTCAADSEIELAYADVAKRL 248
>gi|166197662 chloride intracellular channel 5 isoform a [Homo
sapiens]
Length = 410
Score = 369 bits (947), Expect = e-102
Identities = 176/234 (75%), Positives = 205/234 (87%)
Query: 452 DITLFVKAGYDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPF 511
+I LFVKAG DGESIGNCPFSQRLFMILWLKGV+FNVTTVDLKRKPADL NLAPGT+PPF
Sbjct: 174 EIYLFVKAGIDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLKRKPADLHNLAPGTHPPF 233
Query: 512 MTFDGEVKTDVNKIEEFLEEKLAPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKKDAN 571
+TF+G+VKTDVNKIEEFLEE L P +YPKL +H ESN+AG D+F+KFSA+IKNTK+ N
Sbjct: 234 LTFNGDVKTDVNKIEEFLEETLTPEKYPKLAAKHRESNTAGIDIFSKFSAYIKNTKQQNN 293
Query: 572 EIHEKNLLKALRKLDNYLNSPLPDEIDAYSTEDVTVSGRKFLDGDELTLADCNLLPKLHI 631
E+ L KAL+KLD+YLN+PLP+EIDA + + S RKFLDGDELTLADCNLLPKLH+
Sbjct: 294 AALERGLTKALKKLDDYLNTPLPEEIDANTCGEDKGSRRKFLDGDELTLADCNLLPKLHV 353
Query: 632 IKIVAKKYRDFEFPSEMTGIWRYLNNAYARDEFTNTCPADQEIEHAYSDVAKRM 685
+KIVAKKYR+++ P+EMTG+WRYL NAYARDEFTNTC AD EIE AY+DVAKR+
Sbjct: 354 VKIVAKKYRNYDIPAEMTGLWRYLKNAYARDEFTNTCAADSEIELAYADVAKRL 407
>gi|66346733 chloride intracellular channel 2 [Homo sapiens]
Length = 247
Score = 330 bits (846), Expect = 3e-90
Identities = 157/233 (67%), Positives = 197/233 (84%)
Query: 452 DITLFVKAGYDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPF 511
+I LFVKAG DGESIGNCPF QRLFMILWLKGV FNVTTVD+ RKP +L++LAPGTNPPF
Sbjct: 13 EIELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEELKDLAPGTNPPF 72
Query: 512 MTFDGEVKTDVNKIEEFLEEKLAPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKKDAN 571
+ ++ E+KTD KIEEFLE+ LAPPRYP L ++ ES G ++FAKFSA+IKNT+K+AN
Sbjct: 73 LVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFAKFSAYIKNTQKEAN 132
Query: 572 EIHEKNLLKALRKLDNYLNSPLPDEIDAYSTEDVTVSGRKFLDGDELTLADCNLLPKLHI 631
+ EK+LLK ++LD+YLN+PL DEID S E+ VS R FLDGD+LTLADC+LLPKL+I
Sbjct: 133 KNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLPKLNI 192
Query: 632 IKIVAKKYRDFEFPSEMTGIWRYLNNAYARDEFTNTCPADQEIEHAYSDVAKR 684
IK+ AKKYRDF+ P+E +G+WRYL+NAYAR+EFT+TCP D+EIE+ Y++VAK+
Sbjct: 193 IKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYANVAKQ 245
>gi|14251209 chloride intracellular channel 1 [Homo sapiens]
Length = 241
Score = 313 bits (803), Expect = 3e-85
Identities = 153/238 (64%), Positives = 180/238 (75%)
Query: 449 QEHDITLFVKAGYDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTN 508
++ + LFVKAG DG IGNCPFSQRLFM+LWLKGV FNVTTVD KR+ +Q L PG
Sbjct: 4 EQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQ 63
Query: 509 PPFMTFDGEVKTDVNKIEEFLEEKLAPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKK 568
PF+ + EV TD NKIEEFLE L PPRYPKL +PESN+AG D+FAKFSA+IKN+
Sbjct: 64 LPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNP 123
Query: 569 DANEIHEKNLLKALRKLDNYLNSPLPDEIDAYSTEDVTVSGRKFLDGDELTLADCNLLPK 628
N+ EK LLKAL+ LDNYL SPLP+E+D S ED VS RKFLDG+ELTLADCNLLPK
Sbjct: 124 ALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPK 183
Query: 629 LHIIKIVAKKYRDFEFPSEMTGIWRYLNNAYARDEFTNTCPADQEIEHAYSDVAKRMK 686
LHI+++V KKYR F P G+ RYL+NAYAR+EF +TCP D+EIE AY VAK +K
Sbjct: 184 LHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK 241
>gi|40288290 chloride intracellular channel 3 [Homo sapiens]
Length = 236
Score = 226 bits (576), Expect = 5e-59
Identities = 117/229 (51%), Positives = 152/229 (66%), Gaps = 2/229 (0%)
Query: 450 EHDITLFVKAGYDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNP 509
E + LFVKA DGES+G+CP QRLFM+L LKGV F +TTVD +R P L++ APG+
Sbjct: 3 ETKLQLFVKASEDGESVGHCPSCQRLFMVLLLKGVPFTLTTVDTRRSPDVLKDFAPGSQL 62
Query: 510 PFMTFDGEVKTDVNKIEEFLEEKLAPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKKD 569
P + +D + KTD +IE+FLEE L PP +P L ++ ESN+AGNDVF KFSAFIKN
Sbjct: 63 PILLYDSDAKTDTLQIEDFLEETLGPPDFPSLAPRYRESNTAGNDVFHKFSAFIKNPVPA 122
Query: 570 ANEIHEKNLLKALRKLDNYLNSPLPDEIDAYSTEDVTVSGRKFLDGDELTLADCNLLPKL 629
+E + LL+AL +LD+YL +PL E+ + S R+FLDGD LTLADC+LLPKL
Sbjct: 123 QDEALYQQLLRALARLDSYLRAPLEHEL--AGEPQLRESRRRFLDGDRLTLADCSLLPKL 180
Query: 630 HIIKIVAKKYRDFEFPSEMTGIWRYLNNAYARDEFTNTCPADQEIEHAY 678
HI+ V +R P+E+ G+ RYL++A EF TCP EI AY
Sbjct: 181 HIVDTVCAHFRQAPIPAELRGVRRYLDSAMQEKEFKYTCPHSAEILAAY 229
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 122 bits (306), Expect = 1e-27
Identities = 120/439 (27%), Positives = 171/439 (38%), Gaps = 25/439 (5%)
Query: 30 EPGAAG-GEAEGPEGSEGAE----------EAPRGAAAVKEAGGGGPDRGPEAEARGTRG 78
E G G G+ EGS GAE E +G ++ G G + + E + G
Sbjct: 648 EDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDG 707
Query: 79 AHGET-EAEEGAPE--GAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQREPEDSAAP 135
E E E+G + E+ +GGEE G + E + E G+ + E E+
Sbjct: 708 EEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGE 767
Query: 136 ERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGP 195
+EE E++ E E + E G+ +G G+ E EG G+ E G V EG
Sbjct: 768 REKEEGERKKE--ERAGKEEKGEEEGDQGE-GEEEETEG-RGEEKEEGGEVEGGEVEEGK 823
Query: 196 AGDSVDAEGPLGDNIQAEGPA--GDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAG 253
+ E G+ + EG G+ + EG + E G+ EG E G
Sbjct: 824 GEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEG 883
Query: 254 DPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEV 313
+ G+G E G G+ E EG + + EG E + G+G + E
Sbjct: 884 E--GEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEG 941
Query: 314 AAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEER 373
GE G E W+ EE E G E G+ GE+ G+G +E E EE
Sbjct: 942 EDGEGEGEEE-EGEWEGEEE-EGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEE-EGEEE 998
Query: 374 RERSPEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVN 433
E EG E E G EEE + E G E E + EE EG GE R N
Sbjct: 999 GEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRN 1058
Query: 434 GRREDGEASEPRALGQEHD 452
E+ E + + G+E +
Sbjct: 1059 REEEEEEEGKYQETGEEEN 1077
Score = 113 bits (283), Expect = 5e-25
Identities = 121/432 (28%), Positives = 166/432 (38%), Gaps = 52/432 (12%)
Query: 26 ERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGAHGETEA 85
ERPGE E E + +G E+ + + G +R E E G HGE E
Sbjct: 687 ERPGEGEKELAEKEEWKKRDGEEQEQK-----EREQGHQKERNQEMEEGGEE-EHGEGEE 740
Query: 86 EEGAPEGAEVPQG-GEETSGAQQVEGASP------------GRGAQGEPRGEAQREPEDS 132
EEG E E +G G+E ++VEG G+ +GE G+ Q E E+
Sbjct: 741 EEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGD-QGEGEEE 799
Query: 133 AAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDA 192
R EE E+ EV G G+ + E + E E G+ E EG G+ +
Sbjct: 800 ETEGRGEEKEEGGEVEGGEVEEGKGEREEEE----EEGEGEEEEGEGEEEEGE-GEEEEG 854
Query: 193 EGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEA 252
EG + EG G+ + EG G+ G+ + EG + + EG E
Sbjct: 855 EGKG----EEEGEEGEG-EEEGEEGEGE------GEEEEGEGEGEEEGEGEG------EE 897
Query: 253 GDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSG-DGSLSPQAEAI 311
+ G+G E G G+ E EG + EG G E + G DG + E
Sbjct: 898 EEGEGEGEEEGEGEGEEEEGEGKG----EEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEG 953
Query: 312 EVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDR---VGDGPQQEPG 368
E E G GE + E E +G EE G+ + GE+ G+G ++ G
Sbjct: 954 EWEGEEEEGEGEGEEEGEG--EGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEG 1011
Query: 369 EDEERRERSPEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGE 428
E EE E EG E E GE E + GE E E N EE E
Sbjct: 1012 EGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQE 1071
Query: 429 AARVNGRREDGE 440
R+DGE
Sbjct: 1072 TGEEENERQDGE 1083
Score = 108 bits (270), Expect = 2e-23
Identities = 106/382 (27%), Positives = 145/382 (37%), Gaps = 24/382 (6%)
Query: 35 GGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAE 94
GGE E EG E EE R KE G G E E GE E EEG + E
Sbjct: 730 GGEEEHGEGEE--EEGDREEEEEKEGEGKEEGEGEEVE--------GEREKEEGERKKEE 779
Query: 95 ----VPQGGEETSGAQQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQ-RPEVPE 149
+G EE + E + GRG + E GE + + ER+EE E+ E E
Sbjct: 780 RAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEE 839
Query: 150 GSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDN 209
G E G+ + EG E E G+ EG G+ + EG + EG G+
Sbjct: 840 GEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGE-GEGEEEEGEGEGEEEGEGE-GEE 897
Query: 210 IQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAG-DPAGDGVEA-GVPAG 267
+ EG + + EG + G+ + EG + G D G+G E G G
Sbjct: 898 EEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEG 957
Query: 268 DSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELA 327
+ E EG + + EG G E + G+ + E E GE G GE
Sbjct: 958 EEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEE-EGEEEGEEEGEGEEEGEGEGEEE 1016
Query: 328 WDAAEEAEVPGVKGSEEAAPGDARADAGE-DRVGDGPQQEPGEDEERRERSP---EGPRE 383
+ E EV G +G E + + E ++ G+G + +EE E G E
Sbjct: 1017 EEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEE 1076
Query: 384 EEAAGGEEESPDSSPHGEASRG 405
E GEE S G G
Sbjct: 1077 NERQDGEEYKKVSKIKGSVKYG 1098
Score = 100 bits (249), Expect = 4e-21
Identities = 112/416 (26%), Positives = 158/416 (37%), Gaps = 53/416 (12%)
Query: 37 EAEGPEGSEG----AEEAPRGAAAVKEAGGG-------GPDRGPEAEARGTRGAHGETEA 85
E EG E S+G +E VK GG D +AE + A EA
Sbjct: 589 EKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGK-AKSVGEA 647
Query: 86 EEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRP 145
E+G PEG E +SGA+ + +G + + RGE +R E +EE ++R
Sbjct: 648 EDG-PEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRD 706
Query: 146 EVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGP 205
+ E G + + + E E G+ E EG + + EG + + E
Sbjct: 707 GEEQEQKEREQGHQKERNQEMEEGGEEEH--GEGEEEEGDREEEEEKEGEGKEEGEGEEV 764
Query: 206 LGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVP 265
G+ + EG A + + G+ + EGR + E G+ G VE G
Sbjct: 765 EGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKG 824
Query: 266 AGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGE 325
+ E EG G+ + EG ++ G+G E GE G GE
Sbjct: 825 EREEEEEEGE-GEEEEGEGE-----------EEEGEG---------EEEEGEGKGEEEGE 863
Query: 326 LAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEE 385
E E G EE G+ GE+ G+G +E GE E E EG EEE
Sbjct: 864 -------EGE-----GEEEGEEGEGE---GEEEEGEGEGEEEGEGEGEEEEG-EGEGEEE 907
Query: 386 AAG-GEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGE 440
G GEEE + E G E E + E+G EG E G E+GE
Sbjct: 908 GEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGE 963
Score = 93.6 bits (231), Expect = 5e-19
Identities = 92/316 (29%), Positives = 120/316 (37%), Gaps = 36/316 (11%)
Query: 6 EPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGA---EEAPRGAAAVKEAGG 62
E +G G QG E E GE GGE EG E EG EE +E G
Sbjct: 784 EEKGEEEGDQGEGEEEE--TEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGE 841
Query: 63 GGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPR 122
G + G E G E E EG EG E GEE G + E G G + E
Sbjct: 842 GEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 901
Query: 123 GEAQREPE--------DSAAPERQEEAEQRPEVPEGSASGE--AGDSVDAEGPL-GDNIE 171
GE + E E + E EE E E EG GE G+ + EG G+ E
Sbjct: 902 GEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEE 961
Query: 172 AEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVD 231
EG + E EG G+ G+ + EG G+ + EG + EG +
Sbjct: 962 GEGEGEEEGEGEGEEGE--------GEGEEEEGE-GEGEEEEGEEEGEEEGEG------E 1006
Query: 232 AEGPAGDSVDAEGRVGDSVEAGDPAGDG-VEAGVPAGDSVEAEGPAGDSM----DAEGPA 286
EG + EG V VE + G+G E G G+ E EG ++ + E
Sbjct: 1007 EEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEE 1066
Query: 287 GRARRVSGEPQQSGDG 302
G+ + E + DG
Sbjct: 1067 GKYQETGEEENERQDG 1082
Score = 85.1 bits (209), Expect = 2e-16
Identities = 87/285 (30%), Positives = 109/285 (38%), Gaps = 39/285 (13%)
Query: 3 EAAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGG 62
E E EG +G E E E G GE EG EG EG EE G
Sbjct: 827 EEEEEEGEGEEEEGEGEEEEGEGEE--EEGEGKGEEEGEEG-EGEEEGEEGE-------- 875
Query: 63 GGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQG-GEETSGAQQVEGASPGRGAQGEP 121
G E E G GE E EEG EG E +G GEE G EG G +GE
Sbjct: 876 -GEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEG----EGKGEEEGEEGEG 930
Query: 122 RGEAQR---EPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGD 178
GE + E ED +EE E E EG GE + EG E E G+
Sbjct: 931 EGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEE----EGEG------EGEEGEGE 980
Query: 179 SVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGD 238
E EG G+ + EG + EG + EG + EG V V+ E G+
Sbjct: 981 GEEEEGE-GEGEEEEGEEEGEEEGEG------EEEGEGEGEEEEEGEVEGEVEGEEGEGE 1033
Query: 239 SVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAE 283
+ EG + E + G+G E + E EG ++ + E
Sbjct: 1034 GEEEEGE--EEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEE 1076
Score = 55.1 bits (131), Expect = 2e-07
Identities = 52/172 (30%), Positives = 65/172 (37%), Gaps = 5/172 (2%)
Query: 3 EAAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGG 62
E E +G G +G E E GE G GE E E EG EE G + G
Sbjct: 915 EEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEW-EGEEEEGEGEGEEEGEGE 973
Query: 63 G--GPDRGPEAEARGT-RGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQG 119
G G G E E G GE E EE EG E +G E +VEG G +G
Sbjct: 974 GEEGEGEGEEEEGEGEGEEEEGEEEGEEEG-EGEEEGEGEGEEEEEGEVEGEVEGEEGEG 1032
Query: 120 EPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIE 171
E E E + E + E +R E G+ ++ + E D E
Sbjct: 1033 EGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEE 1084
Score = 36.6 bits (83), Expect = 0.079
Identities = 36/148 (24%), Positives = 53/148 (35%), Gaps = 38/148 (25%)
Query: 332 EEAEVPGVKGSEEAAPG----DARADAGED-----------------------RVGDGPQ 364
EE E+P K E + G + +A E+ V +G
Sbjct: 582 EEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKA 641
Query: 365 QEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAE 424
+ GE E+ E +G EE ++G E + GE +G E E P E
Sbjct: 642 KSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMER----------PGE 691
Query: 425 GSGE-AARVNGRREDGEASEPRALGQEH 451
G E A + ++ DGE E + Q H
Sbjct: 692 GEKELAEKEEWKKRDGEEQEQKEREQGH 719
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 112 bits (281), Expect = 9e-25
Identities = 138/528 (26%), Positives = 208/528 (39%), Gaps = 105/528 (19%)
Query: 3 EAAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGG 62
EA E EG A P+ +V P AE +P + G EA PE + A+ A++ G
Sbjct: 1875 EAPEAEGEAQ-PESE-DVETPEAEWEVQPESEGAEA--PEAEKEAQPETESVEALETEGE 1930
Query: 63 GGPD-RGPEAEA--RGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQG 119
P+ G EA+ + A G+T+ E E E + + S + VE Q
Sbjct: 1931 DEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPES--EDVEALEVEVETQ- 1987
Query: 120 EPRGEAQREPEDSAAPERQ-------EEAEQRPEVPEGSASGEAGDSVDAEG-------- 164
E GEAQ E ED APE + EEA+ + E E ++ + EG
Sbjct: 1988 EAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGD 2047
Query: 165 --PLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEG---PAGDS 219
P D +EA ++ EAEG V ++ P + VDA+ +AEG P +
Sbjct: 2048 AQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQ-------EAEGEAQPESEG 2100
Query: 220 VDAEGRVGDSVDAEGPAGDSVDAEGR-VGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGD 278
V+A G++ AEG + E + + +EA + G+ P + VEA+ G+
Sbjct: 2101 VEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGE----AQPESEGVEAQDAEGE 2156
Query: 279 SM-DAEGPAGRARRVSGEPQQSG------DGSLSPQAEAIEV--AAGESAGRSPGELAWD 329
+ ++EG + +P+ G +G P++E IE A GE+ G A +
Sbjct: 2157 AQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPE 2216
Query: 330 AAEEA--EVPGV---------------------KGSEEAAPGDARADAGEDRVGDGPQQE 366
A EEA E GV KGS + + GD +++ + P+
Sbjct: 2217 AEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDR 2276
Query: 367 P-------GEDEERRERSPEGPREEEAAG---------------GEEESPDS----SPHG 400
P G+ +R S GP A+ G+ SPD+ +PH
Sbjct: 2277 PTPPPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKSTGTPHA 2336
Query: 401 EASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRALG 448
E PE+ S EE P G G E + E +ALG
Sbjct: 2337 ERKATRMYPESSTSEQ--EEAPL---GSRTPEQGASEGYDLQEDQALG 2379
Score = 111 bits (278), Expect = 2e-24
Identities = 129/477 (27%), Positives = 198/477 (41%), Gaps = 62/477 (12%)
Query: 8 EGVAPGPQGPPE------VPAPLAERPGEPGAAGGEAEGPEG-SEGAEEAPRGAAAVKEA 60
E A G Q P + + AP AE +P + G EA EG ++ AE + + EA
Sbjct: 1817 EAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEA 1876
Query: 61 GGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGE 120
+ PE+E T A E + E EGAE P+ +E A P +
Sbjct: 1877 PEAEGEAQPESEDVETPEAEWEVQPES---EGAEAPEAEKE---------AQPETESVEA 1924
Query: 121 PRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAG--DSVDAE---GPLGDNI----- 170
E + EPE A +EAE+ + EG E+ +S +AE P +++
Sbjct: 1925 LETEGEDEPESEGA--EAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEV 1982
Query: 171 -----EAEGPAG------DSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDS 219
EAEG A ++ EAEG + ++ + P D V+A+ P + +A+ G++
Sbjct: 1983 EVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQ-PKSEGEEAQEVEGET 2041
Query: 220 VDAEGRV---GDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEG-- 274
EG D V+A ++ +AEG V ++ P + V D+ EAEG
Sbjct: 2042 QKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDV-------DAQEAEGEA 2094
Query: 275 -PAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEV--AAGESAGRSPGELAWDAA 331
P + ++A G A++ G +G P++E IE A GE+ S G A DA
Sbjct: 2095 QPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAE 2154
Query: 332 EEA--EVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAAGG 389
EA E G++ E + E +G Q E E E E E E
Sbjct: 2155 GEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEA 2214
Query: 390 EEESPDSSPHGE-ASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRRED-GEASEP 444
E ++ P E AE EAQ + +G +GS + + +G+ E+ E+S P
Sbjct: 2215 PEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSP 2271
Score = 97.8 bits (242), Expect = 3e-20
Identities = 120/473 (25%), Positives = 185/473 (39%), Gaps = 64/473 (13%)
Query: 35 GGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEA-------RGTRGAHGETEAEE 87
G EAEG E + + + G RGP EA + RG H + EA E
Sbjct: 1648 GEEAEGEEFCPCEACVRKKVSPMSPKATMGATRGPIKEAFDLQQILQRKRGEHTDGEAAE 1707
Query: 88 GAP-------EGAEVPQGGEET--SGAQQVEGASPGRGAQGEPRGEAQREP-----EDSA 133
AP QG E G Q G G +G R ++P E A
Sbjct: 1708 VAPGKTHTDPTSTRTVQGAEGGLGPGLSQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDA 1767
Query: 134 APERQEEAEQRPEVPEGSASGEA---GDSVDAEGPLG-------DNIEAEGPAG---DSV 180
+ +E E GS GEA G+ + G G DN++ E AG D
Sbjct: 1768 MAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPG 1827
Query: 181 EAEGRVG-DSVDAEG---PAGDSVDAEGPLGDNIQAEG---PAGDSVDAEGRVGDSVDAE 233
+++G G ++ +AEG P + V+A GD +AEG P + V+A G++ E
Sbjct: 1828 QSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEA-QPE 1886
Query: 234 GPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEA------EGPAGDSMDAEGPAG 287
++ +AE V E G A + + P +SVEA + P + +A+
Sbjct: 1887 SEDVETPEAEWEVQPESE-GAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEE 1945
Query: 288 RARRVSGEPQ--------QSGDGSLSPQAE-----AIEVAAGESAGRSPGELAWDAAEEA 334
A+ G+ Q Q + P++E +EV E+ G + E A EA
Sbjct: 1946 AAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEA 2005
Query: 335 EVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAAGGEEESP 394
E + EEA P +A G+ Q+ GE ++ + EA EEE+
Sbjct: 2006 EGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQ 2065
Query: 395 DSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRAL 447
++ + + G A PE++ + A+E E E+ V +GEA + +
Sbjct: 2066 EAEGEVQEAEGEAHPESEDVD--AQEAEGEAQPESEGVEAPEAEGEAQKAEGI 2116
Score = 51.2 bits (121), Expect = 3e-06
Identities = 110/477 (23%), Positives = 158/477 (33%), Gaps = 81/477 (16%)
Query: 29 GEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGAHG------- 81
G PG A E E SEG + A + A+ + D E + +GT A G
Sbjct: 554 GCPGKARAETSQQEASEGGDPA---SPALSLSSLRSDDLQAETQGQGTEQATGAAVTREP 610
Query: 82 ---------ETEAEEGAPEGAEVPQGGEE---TSGAQQVEGASPGRGA---QGEPRGEAQ 126
++E P Q G+ + + +SPG G +G PR
Sbjct: 611 LVLGLSCSWDSEGASSTPSTCTSSQQGQRRHRSRASAMSSPSSPGLGRVAPRGHPRHSHY 670
Query: 127 REPEDSAAPERQEEAEQRPEVPE-------GSASGEAGDSVDAEGPLGDNIEAEGPAGDS 179
R+ D+ +P +Q P PE GS +G S N+ P+ S
Sbjct: 671 RK--DTHSPLDSSVTKQVPRPPERRRACQDGSVPRYSGSSSSTRTQASGNLRP--PSSGS 726
Query: 180 VEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDS 239
+ ++ +G S PA S G N + G AGD A R DS
Sbjct: 727 LPSQDLLGTSSATVTPAVHSDFVSGVSPHNAPSAGWAGD---AGSRTCSPAPIPPHTSDS 783
Query: 240 VDAEGRVGDSVEAGDPAGDG----VEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGE 295
G EA D ++ G P +V S PA A+R
Sbjct: 784 CSKSGAASLGEEARDTPQPSSPLVLQVGRPEQGAVGPHRSHCCSQPGTQPAQEAQR-GPS 842
Query: 296 PQQSG----------DGSLSPQAEAIEV----AAGESAGRSPGELAWDAAEEAEVPGVKG 341
P+ S G PQ + ++ +S R PG + + PG
Sbjct: 843 PEASWLCGRYCPTPPRGRPCPQRRSSSCGSTGSSHQSTARGPGGSPQEGTRQ---PGPTP 899
Query: 342 SEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAAGGEEES--PDSSPH 399
S G +R + G G EE+ RS GP+ +E A G S P SSP
Sbjct: 900 SPGPNSGASRRSSASQGAGSR-----GLSEEKTLRSGGGPQGQEEASGVSPSSLPRSSPE 954
Query: 400 G---EASRGAAEPEAQLSNHLAEE----------GPAEGSGEAARVNGRREDGEASE 443
E E ++ LA+E GP G+ + G E +A +
Sbjct: 955 AVVREWLDNIPEEPILMTYELADETTGAAGGGLRGPEVDPGDDHSLEGLGEPAQAGQ 1011
Score = 46.6 bits (109), Expect = 8e-05
Identities = 127/526 (24%), Positives = 175/526 (33%), Gaps = 82/526 (15%)
Query: 6 EPEGVAPG--PQGPPE--VPAPLAERPGEP------------GAAGGEAEGPEGSEGAEE 49
E GV+P P+ PE V L P EP GAAGG GPE G +
Sbjct: 939 EASGVSPSSLPRSSPEAVVREWLDNIPEEPILMTYELADETTGAAGGGLRGPEVDPGDDH 998
Query: 50 APRGAAAVKEAG----GGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGA 105
+ G +AG G P + PE E + ++ EG P+GA P+G E
Sbjct: 999 SLEGLGEPAQAGQQSLEGDPGQDPEPEGALLGSSDTGPQSGEGVPQGA-APEGVSEAPAE 1057
Query: 106 QQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGP 165
+ +P G + R A P R + Q GS G + P
Sbjct: 1058 AGADREAPA-GCRVSLR----------ALPGRVSASTQIMRALMGSKQGRPSSVPEVSRP 1106
Query: 166 LGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGP--------AG 217
+ + A + A ++ + D PA + P + +
Sbjct: 1107 MARRLSCSAGALITCLASLQLFEE-DLGSPASKVRFKDSPRYQELLSISKDLWPGCDVGE 1165
Query: 218 DSVD----------AEGRVGDSVDAEG---PAGDSVDAEGRVGDSVEAGDP-AGDGVEAG 263
D +D A +G E + VD G S E+ P A DG
Sbjct: 1166 DQLDSGLWELTWSQALPDLGSHAMTENFTPTSSSGVDISSGSGGSGESSVPCAMDGTLVT 1225
Query: 264 VPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSP 323
++ DS E P + + Q L+ +A A E+ S
Sbjct: 1226 QGTELPLKTSNQRPDSRTYESPGD----LENQQQCCFPTFLNARACACATNEDEAERDSE 1281
Query: 324 GELAWDAAEEAEVPGVKGS---EEAAPGDARADAGEDRVG-DGPQQEPGEDEE------R 373
+ A E+ V+ EE G E+ V + + E G EE
Sbjct: 1282 EQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEET 1341
Query: 374 RERSPEGPREEEA-------AGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEG-PAEG 425
+E EG +EEEA GGE + E G PE L EEG EG
Sbjct: 1342 KETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEG---PEGGLQGEALEEGLKEEG 1398
Query: 426 SGEAARVNGRREDGEASEPRALG-QEHDITLFVKAGYDGESIGNCP 470
E V+G +E EAS P G QE D +AG S CP
Sbjct: 1399 LPEEGSVHG-QELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCP 1443
Score = 43.9 bits (102), Expect = 5e-04
Identities = 70/257 (27%), Positives = 89/257 (34%), Gaps = 45/257 (17%)
Query: 14 PQGPPEVPAPLAERPGEPGAAGGE----AEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGP 69
P P P P R G+ G A GP GS G GP+ G
Sbjct: 854 PTPPRGRPCP-QRRSSSCGSTGSSHQSTARGPGGSP-----QEGTRQPGPTPSPGPNSGA 907
Query: 70 EAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQREP 129
+ ++GA +EE PQG EE S G SP + P RE
Sbjct: 908 SRRSSASQGAGSRGLSEEKTLRSGGGPQGQEEAS------GVSPSSLPRSSPEA-VVREW 960
Query: 130 EDSAAPERQEEAEQRPEVPEGSASG-------EAGDSVDAEGPLGDNIEA-----EGPAG 177
D+ E + + G+A G + GD EG LG+ +A EG G
Sbjct: 961 LDNIPEEPILMTYELADETTGAAGGGLRGPEVDPGDDHSLEG-LGEPAQAGQQSLEGDPG 1019
Query: 178 DSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAG 237
E EG + S D +G+ V Q P G S +A G D E PAG
Sbjct: 1020 QDPEPEGALLGSSDTGPQSGEGVP---------QGAAPEGVS-EAPAEAG--ADREAPAG 1067
Query: 238 DSVDAE---GRVGDSVE 251
V GRV S +
Sbjct: 1068 CRVSLRALPGRVSASTQ 1084
Score = 38.9 bits (89), Expect = 0.016
Identities = 67/288 (23%), Positives = 105/288 (36%), Gaps = 30/288 (10%)
Query: 141 AEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSV 200
+ QRP+ + G+ + P N A A + EAE DS + +
Sbjct: 1235 SNQRPDSRTYESPGDLENQQQCCFPTFLNARACACATNEDEAER---DSEEQRASSNLEQ 1291
Query: 201 DAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSV---EAGDPAG 257
AE + + +Q E + + EG ++V E ++ EG + V E + G
Sbjct: 1292 LAENTVQEEVQLE-ETKEGTEGEGLQEEAVQLE----ETKTEEGLQEEGVQLEETKETEG 1346
Query: 258 DGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGE 317
+G + + +E G G+ + EG E ++ +G L Q EA+E E
Sbjct: 1347 EGQQEEEAQLEEIEETG--GEGLQEEGVQLE------EVKEGPEGGL--QGEALEEGLKE 1396
Query: 318 SAGRSPGELAWDAAEEAEVPGVKGSEEAAP------GDARADAGEDRVGDGPQQEPGEDE 371
G + EA P KGS+E P G A A A E +G ++
Sbjct: 1397 EGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASA-EPCPAEGTEEPTEPPS 1455
Query: 372 ERRERSPEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAE 419
E P E +G + E P G G +AQ + AE
Sbjct: 1456 HLSETDPSA--SERQSGSQLEPGLEKPPGATMMGQEHTQAQPTQGAAE 1501
Score = 38.5 bits (88), Expect = 0.021
Identities = 59/234 (25%), Positives = 89/234 (38%), Gaps = 38/234 (16%)
Query: 25 AERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGAHGETE 84
AER E A E + AE + ++E G G + EA ET+
Sbjct: 1276 AERDSEEQRASSNLE-----QLAENTVQEEVQLEETKEGTEGEGLQEEAVQLE----ETK 1326
Query: 85 AEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQREP-EDSAAPERQEEAEQ 143
EEG E + +ET G +G+ EAQ E E++ QEE Q
Sbjct: 1327 TEEGLQEEGVQLEETKETEG-------------EGQQEEEAQLEEIEETGGEGLQEEGVQ 1373
Query: 144 RPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAE 203
EV EG G G++++ EG + + EG SV + + +A P G +
Sbjct: 1374 LEEVKEGPEGGLQGEALE-EGLKEEGLPEEG----SVHGQ----ELSEASSPDGKGSQED 1424
Query: 204 GPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPA----GDSVDAEGRVGDSVEAG 253
P+ + + G A S + G E P+ D +E + G +E G
Sbjct: 1425 DPVQE--EEAGRASASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPG 1476
Score = 37.7 bits (86), Expect = 0.036
Identities = 57/245 (23%), Positives = 81/245 (33%), Gaps = 19/245 (7%)
Query: 114 GRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAE 173
GRG Q P+ E P ++ ER ++ SG G ++
Sbjct: 396 GRGGQPGPKYEIWTNPLHASQGERVAARKRWGLAQHVRCSGLWGHGTAGRERCSQ--DSA 453
Query: 174 GPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAE 233
PA + EG +S D VD+ P I AE AG S+ + G +D
Sbjct: 454 SPASSTGLPEGSEPESSCCPRTPEDGVDSASPSAQ-IGAERKAGGSLGEDP--GLCIDGA 510
Query: 234 GPAGDSVDA---------EGRVGDS-VEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAE 283
G G EG DS G G G P G +A +E
Sbjct: 511 GLGGPEQGGRLTPRARSEEGASSDSSASTGSHEGSSEWGGRPQGCPGKARAETSQQEASE 570
Query: 284 GPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGEL----AWDAAEEAEVPGV 339
G + +S +S D Q + E A G + R P L +WD+ + P
Sbjct: 571 GGDPASPALSLSSLRSDDLQAETQGQGTEQATGAAVTREPLVLGLSCSWDSEGASSTPST 630
Query: 340 KGSEE 344
S +
Sbjct: 631 CTSSQ 635
Score = 29.6 bits (65), Expect = 9.7
Identities = 40/152 (26%), Positives = 60/152 (39%), Gaps = 37/152 (24%)
Query: 224 GRVGDSVDAEGPAGDSVDAEGRVGDS----------VEAGDPAGDGVEAGVPAGDSVEAE 273
GR S D+ PA + EG +S V++ P+ + A AG S+ E
Sbjct: 444 GRERCSQDSASPASSTGLPEGSEPESSCCPRTPEDGVDSASPSAQ-IGAERKAGGSL-GE 501
Query: 274 GPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESA---GRSPGELAWDA 330
P G +D G G P+Q G L+P+A + E A+ +S+ G G W
Sbjct: 502 DP-GLCIDGAGLGG--------PEQG--GRLTPRARSEEGASSDSSASTGSHEGSSEWG- 549
Query: 331 AEEAEVPGVKGSEEAAPGDARADAGEDRVGDG 362
G + PG ARA+ + +G
Sbjct: 550 ----------GRPQGCPGKARAETSQQEASEG 571
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 98.6 bits (244), Expect = 2e-20
Identities = 145/497 (29%), Positives = 191/497 (38%), Gaps = 64/497 (12%)
Query: 2 AEAAEPEGVAPGPQGPPEVPAPLAE--RPGEPGAAGGE----AEGPEGSEGAEEAPRGAA 55
A A+ E G +GP P E PG PG AG +G G++G+ AP A
Sbjct: 370 APGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAG 429
Query: 56 AVKEAGGGGPDRGPEAEARGTRGAHGET--------EAEEGAPEGAEVPQGGEETSGAQQ 107
A G GP GP+ A G G G+T + E+G P+G P G + G
Sbjct: 430 APGFPGPRGPP-GPQG-ATGPLGPKGQTGEPGIAGFKGEQG-PKGEPGPAGPQGAPGPAG 486
Query: 108 VEGASPGRGAQGEPRGEAQREP--EDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGP 165
EG RGA+GEP G P E A R + P+G A GE G S GP
Sbjct: 487 EEGK---RGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKG-APGERGPS-GLAGP 541
Query: 166 LGDNIEAEGPAGDSVE-AEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEG 224
G N + P + A G G DA GP G V G G++ GP G A G
Sbjct: 542 KGANGDPGRPGEPGLPGARGLTGRPGDA-GPQG-KVGPSGAPGED-GRPGPPGPQ-GARG 597
Query: 225 RVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEA-------EGPAG 277
+ G + GP G A G G + E G P G+ G+P D GPAG
Sbjct: 598 QPG-VMGFPGPKG----ANGEPGKAGEKGLPGAPGLR-GLPGKDGETGAAGPPGPAGPAG 651
Query: 278 D--SMDAEGPAG-----RARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDA 330
+ A GP+G GE + GD + +A A + PGE
Sbjct: 652 ERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG 711
Query: 331 AEEAE----VPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEA 386
A+ + +PG G++ P A AG GP G ER GP+ +
Sbjct: 712 AQGLQGPRGLPGTPGTD--GPKGASGPAGPPG-AQGPPGLQGMPGERGAAGIAGPKGDRG 768
Query: 387 AGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRA 446
G E+ P+ +P + RG P + GPA +GE V G A A
Sbjct: 769 DVG-EKGPEGAPGKDGGRGLTGP-------IGPPGPAGANGEKGEVGPPGPAGSAGARGA 820
Query: 447 LGQEHDITLFVKAGYDG 463
G+ + AG+ G
Sbjct: 821 PGERGETGPPGPAGFAG 837
Score = 97.1 bits (240), Expect = 5e-20
Identities = 147/468 (31%), Positives = 181/468 (38%), Gaps = 95/468 (20%)
Query: 2 AEAAEPEGV--APGPQGPPEVPAPLAER--PGEPGAAG--GEAE--GPEGSEG-----AE 48
A A P+G APGPQGP V P R G PGA G G A GP GS G
Sbjct: 860 AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 919
Query: 49 EAPRGAAAVKEAGG--GGPDRGPEAEARGTRGAHGET-EAEEGAPEGAEVPQGGEETSGA 105
P G K A G G P R E +G G GE E + P GAE P G + +G
Sbjct: 920 PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 979
Query: 106 QQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGP 165
+ + G RG +G P P S P +Q A G +GD GP
Sbjct: 980 RGIVGLPGQRGERGFP-----GLPGPSGEPGKQ------------GAPGASGDR-GPPGP 1021
Query: 166 LGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGR 225
+G GPAG+ GR G S A+GP G A G GD G G +V A G
Sbjct: 1022 VGPP-GLTGPAGE----PGREG-SPGADGPPGRD-GAAGVKGD----RGETG-AVGAPGA 1069
Query: 226 VGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGP 285
G + GPAG + G+ GD EAG G A +GP GD +A P
Sbjct: 1070 PGPP-GSPGPAGPT----GKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP 1124
Query: 286 AGRARR----------VSGEPQQSGD-GSLSPQAEAIEVAAGESAGRS-PGELAWDAAEE 333
R + + G P SGD G+ P AG S R PG + +
Sbjct: 1125 GERGLKGHRGFTGLQGLPGPPGPSGDQGASGP--------AGPSGPRGPPGPVGPSGKDG 1176
Query: 334 AE-VPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAA----G 388
A +PG G P R +GE GP PG P GP + +A G
Sbjct: 1177 ANGIPGPIG-----PPGPRGRSGE----TGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLG 1227
Query: 389 GEEESPDSSPHGEASRGA-------AEPEA---QLSNHLAEEGPAEGS 426
E+ PD + A + A AE +A L+N + EGS
Sbjct: 1228 PREKGPDPLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGS 1275
Score = 90.1 bits (222), Expect = 6e-18
Identities = 137/468 (29%), Positives = 174/468 (37%), Gaps = 83/468 (17%)
Query: 7 PEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAE----GPEGSEGAEEAPRGAAAVKEAGG 62
PEG APG G + P+ PG GA G + E GP GS GA AP G
Sbjct: 775 PEG-APGKDGGRGLTGPIGP-PGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 832
Query: 63 GGPDRGPEAEAR-GTRGAHGET--EAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQG 119
G P A+ + G +G GE + + GAP G + P G G V G RGAQG
Sbjct: 833 AGFAGPPGADGQPGAKGEQGEAGQKGDAGAP-GPQGPSGAPGPQGPTGVTGPKGARGAQG 891
Query: 120 EPRGEAQREPEDSAAPERQEEAEQRPEVPEGSAS----GEAGDSVDAEGPLGDNIEA--E 173
P P P P S G GDS GP G E +
Sbjct: 892 PPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS----GPPGRAGEPGLQ 947
Query: 174 GPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDS--VDAEGRVGDS-- 229
GPAG E +G GD +GP+G AEGP G +G AG V G+ G+
Sbjct: 948 GPAGPPGE-KGEPGD----DGPSG----AEGPPGP----QGLAGQRGIVGLPGQRGERGF 994
Query: 230 VDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGD-----SMDAEG 284
GP+G+ +G G S + G P G P G GPAG+ S A+G
Sbjct: 995 PGLPGPSGEP-GKQGAPGASGDRGPPGPVG-----PPG----LTGPAGEPGREGSPGADG 1044
Query: 285 PAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEE 344
P GR DG+ + + E A + G +PG PG G
Sbjct: 1045 PPGR------------DGAAGVKGDRGETGAVGAPG-APGP-----------PGSPGP-- 1078
Query: 345 AAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHG--EA 402
A P + D GE GP G R + P+GPR ++ GE H
Sbjct: 1079 AGPTGKQGDRGEAGA-QGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTG 1137
Query: 403 SRGAAEPEAQLSNHLAE--EGPAEGSGEAARVNGRREDGEASEPRALG 448
+G P + A GP+ G V +DG P +G
Sbjct: 1138 LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIG 1185
Score = 87.0 bits (214), Expect = 5e-17
Identities = 134/478 (28%), Positives = 176/478 (36%), Gaps = 69/478 (14%)
Query: 7 PEGVAPGPQGPPEVPAPLAERPGEPGAAGGE-AEGPEGSEGAEEAPRGAAAVKEAGGGGP 65
P+G PGP GP P P E G+ GA G GP G G AP + G GP
Sbjct: 469 PKG-EPGPAGPQGAPGPAGEE-GKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGP 526
Query: 66 -----DRGPEAEARGTRGAHGE--TEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQ 118
+RGP A G +GA+G+ E G P GA G +G Q G S G
Sbjct: 527 KGAPGERGPSGLA-GPKGANGDPGRPGEPGLP-GARGLTGRPGDAGPQGKVGPSGAPGED 584
Query: 119 GEPRGEAQREPEDSAAPERQEEAEQRPEV-----PEGSASGEAGDSVDAEGPLGDNIEAE 173
G P P + A +P V P+G A+GE G + + P +
Sbjct: 585 GRP------------GPPGPQGARGQPGVMGFPGPKG-ANGEPGKAGEKGLPGAPGLRGL 631
Query: 174 GPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQA-EGPAGDSVDAEGRVGD-SVD 231
A G G + GPAG+ + P Q GP G + G+ GD V
Sbjct: 632 PGKDGETGAAGPPGPA----GPAGERGEQGAPGPSGFQGLPGPPGPPGEG-GKPGDQGVP 686
Query: 232 AEGPAGDSVDAEGRVGDSVEAGDPAGDGVEA-----GVPAGDSVE-AEGPAGDSMDAEGP 285
E A V G G E G P G++ G P D + A GPAG A+GP
Sbjct: 687 GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP-GAQGP 745
Query: 286 AGRARRVSGEPQQSG-DGSLSPQAEAIEV-------AAGESAGR------SPGELAWDAA 331
G + G P + G G P+ + +V A G+ GR P A
Sbjct: 746 PG----LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANG 801
Query: 332 EEAEV--PGVKGSEEA--APGDARADAGEDRVG-DGPQQEPGEDEERRERSPEGPREEEA 386
E+ EV PG GS A APG+ G GP G+ + E+ G + +
Sbjct: 802 EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 861
Query: 387 AGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEP 444
A G + P +P + G P+ G G A RV +G P
Sbjct: 862 APG-PQGPSGAPGPQGPTGVTGPKGARGAQ-GPPGATGFPGAAGRVGPPGSNGNPGPP 917
Score = 84.7 bits (208), Expect = 3e-16
Identities = 145/515 (28%), Positives = 187/515 (36%), Gaps = 102/515 (19%)
Query: 7 PEGVAPGPQGPPEVPAPLAER-----PGEPGAAGGEAE-------GPEGSEGAEEAP--R 52
P+G PGPQGP P +R G PG G + E GP G G P
Sbjct: 118 PKG-PPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLG 176
Query: 53 GAAAVKEAGG-----GGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQ 107
G A + AGG GG G G G G P GA PQG + G
Sbjct: 177 GNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPP-----GPAGAPGPQGFQGNPGEPG 231
Query: 108 VEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGS---------------- 151
G S G +G P G + +D A + + E+ P P+G+
Sbjct: 232 EPGVSGPMGPRGPP-GPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHR 290
Query: 152 -------ASGEAG-DSVDAE----------GPLGD-NIEAE----GPAGDSVEAEGRVGD 188
A GEAG V E GP+G + E GPAG + A G G
Sbjct: 291 GYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAG-AAGARGNDGQ 349
Query: 189 SVDAEGPAGDSVDAEGP-LGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVG 247
A GP G A GP A+G AG + A G G A+GP G+ G G
Sbjct: 350 PGPA-GPPGPVGPAGGPGFPGAPGAKGEAGPT-GARGPEG----AQGPRGEP-GTPGSPG 402
Query: 248 DSVEAGDPAGDGV-----EAGVPA-GDSVEAEGPAG--DSMDAEGPAGRARRVSGEPQQS 299
+ +G+P DG+ AG P + GP G A GP G + +GEP +
Sbjct: 403 PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG-PKGQTGEPGIA 461
Query: 300 G-DGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGV----KGSEEAAPGDARADA 354
G G P+ E AG P E GV E APG+ R
Sbjct: 462 GFKGEQGPKGE--PGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGN-RGFP 518
Query: 355 GEDRVGDGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHGEASR-GAAEPEAQL 413
G+D + GP+ PGE P+G + GE P + G R G A P+ ++
Sbjct: 519 GQDGLA-GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGA--RGLTGRPGDAGPQGKV 575
Query: 414 SNHLAEEGPAEGSGEAARVNGRREDGEASEPRALG 448
GP+ GE R G +P +G
Sbjct: 576 -------GPSGAPGEDGRPGPPGPQGARGQPGVMG 603
Score = 78.2 bits (191), Expect = 2e-14
Identities = 140/520 (26%), Positives = 183/520 (35%), Gaps = 105/520 (20%)
Query: 3 EAAEP----EGVAPGPQGPPEVPAPLAERPGEPGAAGGEA----EGPEGSEGAEEAPRGA 54
EA +P E PGPQG P PG PG G +G +G GA +
Sbjct: 256 EAGKPGKAGERGPPGPQGARGFPGT----PGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 311
Query: 55 AAVKEAGGGGP--------DRGPEAEARGTRGAHG-ETEAEEGAPEGAEVPQGGEETSGA 105
+ E G GP +RG A G GA G + + P G P GG GA
Sbjct: 312 GSPGENGSPGPMGPRGLPGERGRTGPA-GAAGARGNDGQPGPAGPPGPVGPAGGPGFPGA 370
Query: 106 QQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSV-DAEG 164
GA+GE R PE + P R E P G++ D + A+G
Sbjct: 371 P---------GAKGEAGPTGARGPEGAQGP-RGEPGTPGSPGPAGASGNPGTDGIPGAKG 420
Query: 165 PLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQA-----------E 213
G A G AG A G G GP G A GPLG Q +
Sbjct: 421 SAG----APGIAG----APGFPG----PRGPPGPQ-GATGPLGPKGQTGEPGIAGFKGEQ 467
Query: 214 GPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAG--DPAGDGVEAGVPAGDSVE 271
GP G+ G G A GPAG+ EG+ G E G P G E G P
Sbjct: 468 GPKGE----PGPAGPQ-GAPGPAGE----EGKRGARGEPGGVGPIGPPGERGAPGNRGFP 518
Query: 272 AE----GPAGDSMDAEGPAGRA--RRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGE 325
+ GP G + GP+G A + +G+P + G+ L P A + G++ +
Sbjct: 519 GQDGLAGPKG-APGERGPSGLAGPKGANGDPGRPGEPGL-PGARGLTGRPGDAGPQGKVG 576
Query: 326 LAWDAAEEAEVPGVKGSEEAA--------PGDARADAGEDRVGD-------GPQQEPGED 370
+ E+ PG G + A PG A+ + G+ G + PG+D
Sbjct: 577 PSGAPGEDGR-PGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKD 635
Query: 371 EERRERSPEGPREEEAAGGEEESPDSS-------PHGEASRGAAEPEAQLSNHLAEEGPA 423
E P GP GE+ +P S P G G + + G
Sbjct: 636 GETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLV 695
Query: 424 EGSGEAARVNGRREDGEASEPRALGQEHDITLFVKAGYDG 463
GE R GE P A G + L G DG
Sbjct: 696 GPRGE------RGFPGERGSPGAQGLQGPRGLPGTPGTDG 729
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 98.6 bits (244), Expect = 2e-20
Identities = 145/497 (29%), Positives = 191/497 (38%), Gaps = 64/497 (12%)
Query: 2 AEAAEPEGVAPGPQGPPEVPAPLAE--RPGEPGAAGGE----AEGPEGSEGAEEAPRGAA 55
A A+ E G +GP P E PG PG AG +G G++G+ AP A
Sbjct: 301 APGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAG 360
Query: 56 AVKEAGGGGPDRGPEAEARGTRGAHGET--------EAEEGAPEGAEVPQGGEETSGAQQ 107
A G GP GP+ A G G G+T + E+G P+G P G + G
Sbjct: 361 APGFPGPRGPP-GPQG-ATGPLGPKGQTGEPGIAGFKGEQG-PKGEPGPAGPQGAPGPAG 417
Query: 108 VEGASPGRGAQGEPRGEAQREP--EDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGP 165
EG RGA+GEP G P E A R + P+G A GE G S GP
Sbjct: 418 EEGK---RGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKG-APGERGPS-GLAGP 472
Query: 166 LGDNIEAEGPAGDSVE-AEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEG 224
G N + P + A G G DA GP G V G G++ GP G A G
Sbjct: 473 KGANGDPGRPGEPGLPGARGLTGRPGDA-GPQG-KVGPSGAPGED-GRPGPPGPQ-GARG 528
Query: 225 RVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEA-------EGPAG 277
+ G + GP G A G G + E G P G+ G+P D GPAG
Sbjct: 529 QPG-VMGFPGPKG----ANGEPGKAGEKGLPGAPGLR-GLPGKDGETGAAGPPGPAGPAG 582
Query: 278 D--SMDAEGPAG-----RARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDA 330
+ A GP+G GE + GD + +A A + PGE
Sbjct: 583 ERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG 642
Query: 331 AEEAE----VPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEA 386
A+ + +PG G++ P A AG GP G ER GP+ +
Sbjct: 643 AQGLQGPRGLPGTPGTD--GPKGASGPAGPPG-AQGPPGLQGMPGERGAAGIAGPKGDRG 699
Query: 387 AGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRA 446
G E+ P+ +P + RG P + GPA +GE V G A A
Sbjct: 700 DVG-EKGPEGAPGKDGGRGLTGP-------IGPPGPAGANGEKGEVGPPGPAGSAGARGA 751
Query: 447 LGQEHDITLFVKAGYDG 463
G+ + AG+ G
Sbjct: 752 PGERGETGPPGPAGFAG 768
Score = 97.1 bits (240), Expect = 5e-20
Identities = 147/468 (31%), Positives = 181/468 (38%), Gaps = 95/468 (20%)
Query: 2 AEAAEPEGV--APGPQGPPEVPAPLAER--PGEPGAAG--GEAE--GPEGSEG-----AE 48
A A P+G APGPQGP V P R G PGA G G A GP GS G
Sbjct: 791 AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 850
Query: 49 EAPRGAAAVKEAGG--GGPDRGPEAEARGTRGAHGET-EAEEGAPEGAEVPQGGEETSGA 105
P G K A G G P R E +G G GE E + P GAE P G + +G
Sbjct: 851 PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 910
Query: 106 QQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGP 165
+ + G RG +G P P S P +Q A G +GD GP
Sbjct: 911 RGIVGLPGQRGERGFP-----GLPGPSGEPGKQ------------GAPGASGDR-GPPGP 952
Query: 166 LGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGR 225
+G GPAG+ GR G S A+GP G A G GD G G +V A G
Sbjct: 953 VGPP-GLTGPAGE----PGREG-SPGADGPPGRD-GAAGVKGD----RGETG-AVGAPGA 1000
Query: 226 VGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGP 285
G + GPAG + G+ GD EAG G A +GP GD +A P
Sbjct: 1001 PGPP-GSPGPAGPT----GKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP 1055
Query: 286 AGRARR----------VSGEPQQSGD-GSLSPQAEAIEVAAGESAGRS-PGELAWDAAEE 333
R + + G P SGD G+ P AG S R PG + +
Sbjct: 1056 GERGLKGHRGFTGLQGLPGPPGPSGDQGASGP--------AGPSGPRGPPGPVGPSGKDG 1107
Query: 334 AE-VPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAA----G 388
A +PG G P R +GE GP PG P GP + +A G
Sbjct: 1108 ANGIPGPIG-----PPGPRGRSGE----TGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLG 1158
Query: 389 GEEESPDSSPHGEASRGA-------AEPEA---QLSNHLAEEGPAEGS 426
E+ PD + A + A AE +A L+N + EGS
Sbjct: 1159 PREKGPDPLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGS 1206
Score = 90.1 bits (222), Expect = 6e-18
Identities = 137/468 (29%), Positives = 174/468 (37%), Gaps = 83/468 (17%)
Query: 7 PEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAE----GPEGSEGAEEAPRGAAAVKEAGG 62
PEG APG G + P+ PG GA G + E GP GS GA AP G
Sbjct: 706 PEG-APGKDGGRGLTGPIGP-PGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 763
Query: 63 GGPDRGPEAEAR-GTRGAHGET--EAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQG 119
G P A+ + G +G GE + + GAP G + P G G V G RGAQG
Sbjct: 764 AGFAGPPGADGQPGAKGEQGEAGQKGDAGAP-GPQGPSGAPGPQGPTGVTGPKGARGAQG 822
Query: 120 EPRGEAQREPEDSAAPERQEEAEQRPEVPEGSAS----GEAGDSVDAEGPLGDNIEA--E 173
P P P P S G GDS GP G E +
Sbjct: 823 PPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS----GPPGRAGEPGLQ 878
Query: 174 GPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDS--VDAEGRVGDS-- 229
GPAG E +G GD +GP+G AEGP G +G AG V G+ G+
Sbjct: 879 GPAGPPGE-KGEPGD----DGPSG----AEGPPGP----QGLAGQRGIVGLPGQRGERGF 925
Query: 230 VDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGD-----SMDAEG 284
GP+G+ +G G S + G P G P G GPAG+ S A+G
Sbjct: 926 PGLPGPSGEP-GKQGAPGASGDRGPPGPVG-----PPG----LTGPAGEPGREGSPGADG 975
Query: 285 PAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEE 344
P GR DG+ + + E A + G +PG PG G
Sbjct: 976 PPGR------------DGAAGVKGDRGETGAVGAPG-APGP-----------PGSPGP-- 1009
Query: 345 AAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHG--EA 402
A P + D GE GP G R + P+GPR ++ GE H
Sbjct: 1010 AGPTGKQGDRGEAGA-QGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTG 1068
Query: 403 SRGAAEPEAQLSNHLAE--EGPAEGSGEAARVNGRREDGEASEPRALG 448
+G P + A GP+ G V +DG P +G
Sbjct: 1069 LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIG 1116
Score = 87.0 bits (214), Expect = 5e-17
Identities = 134/478 (28%), Positives = 176/478 (36%), Gaps = 69/478 (14%)
Query: 7 PEGVAPGPQGPPEVPAPLAERPGEPGAAGGE-AEGPEGSEGAEEAPRGAAAVKEAGGGGP 65
P+G PGP GP P P E G+ GA G GP G G AP + G GP
Sbjct: 400 PKG-EPGPAGPQGAPGPAGEE-GKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGP 457
Query: 66 -----DRGPEAEARGTRGAHGE--TEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQ 118
+RGP A G +GA+G+ E G P GA G +G Q G S G
Sbjct: 458 KGAPGERGPSGLA-GPKGANGDPGRPGEPGLP-GARGLTGRPGDAGPQGKVGPSGAPGED 515
Query: 119 GEPRGEAQREPEDSAAPERQEEAEQRPEV-----PEGSASGEAGDSVDAEGPLGDNIEAE 173
G P P + A +P V P+G A+GE G + + P +
Sbjct: 516 GRP------------GPPGPQGARGQPGVMGFPGPKG-ANGEPGKAGEKGLPGAPGLRGL 562
Query: 174 GPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQA-EGPAGDSVDAEGRVGD-SVD 231
A G G + GPAG+ + P Q GP G + G+ GD V
Sbjct: 563 PGKDGETGAAGPPGPA----GPAGERGEQGAPGPSGFQGLPGPPGPPGEG-GKPGDQGVP 617
Query: 232 AEGPAGDSVDAEGRVGDSVEAGDPAGDGVEA-----GVPAGDSVE-AEGPAGDSMDAEGP 285
E A V G G E G P G++ G P D + A GPAG A+GP
Sbjct: 618 GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP-GAQGP 676
Query: 286 AGRARRVSGEPQQSG-DGSLSPQAEAIEV-------AAGESAGR------SPGELAWDAA 331
G + G P + G G P+ + +V A G+ GR P A
Sbjct: 677 PG----LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANG 732
Query: 332 EEAEV--PGVKGSEEA--APGDARADAGEDRVG-DGPQQEPGEDEERRERSPEGPREEEA 386
E+ EV PG GS A APG+ G GP G+ + E+ G + +
Sbjct: 733 EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 792
Query: 387 AGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEP 444
A G + P +P + G P+ G G A RV +G P
Sbjct: 793 APG-PQGPSGAPGPQGPTGVTGPKGARGAQ-GPPGATGFPGAAGRVGPPGSNGNPGPP 848
Score = 84.7 bits (208), Expect = 3e-16
Identities = 145/515 (28%), Positives = 187/515 (36%), Gaps = 102/515 (19%)
Query: 7 PEGVAPGPQGPPEVPAPLAER-----PGEPGAAGGEAE-------GPEGSEGAEEAP--R 52
P+G PGPQGP P +R G PG G + E GP G G P
Sbjct: 49 PKG-PPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLG 107
Query: 53 GAAAVKEAGG-----GGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQ 107
G A + AGG GG G G G G P GA PQG + G
Sbjct: 108 GNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPP-----GPAGAPGPQGFQGNPGEPG 162
Query: 108 VEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGS---------------- 151
G S G +G P G + +D A + + E+ P P+G+
Sbjct: 163 EPGVSGPMGPRGPP-GPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHR 221
Query: 152 -------ASGEAG-DSVDAE----------GPLGD-NIEAE----GPAGDSVEAEGRVGD 188
A GEAG V E GP+G + E GPAG + A G G
Sbjct: 222 GYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAG-AAGARGNDGQ 280
Query: 189 SVDAEGPAGDSVDAEGP-LGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVG 247
A GP G A GP A+G AG + A G G A+GP G+ G G
Sbjct: 281 PGPA-GPPGPVGPAGGPGFPGAPGAKGEAGPT-GARGPEG----AQGPRGEP-GTPGSPG 333
Query: 248 DSVEAGDPAGDGV-----EAGVPA-GDSVEAEGPAG--DSMDAEGPAGRARRVSGEPQQS 299
+ +G+P DG+ AG P + GP G A GP G + +GEP +
Sbjct: 334 PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG-PKGQTGEPGIA 392
Query: 300 G-DGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGV----KGSEEAAPGDARADA 354
G G P+ E AG P E GV E APG+ R
Sbjct: 393 GFKGEQGPKGE--PGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGN-RGFP 449
Query: 355 GEDRVGDGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHGEASR-GAAEPEAQL 413
G+D + GP+ PGE P+G + GE P + G R G A P+ ++
Sbjct: 450 GQDGLA-GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGA--RGLTGRPGDAGPQGKV 506
Query: 414 SNHLAEEGPAEGSGEAARVNGRREDGEASEPRALG 448
GP+ GE R G +P +G
Sbjct: 507 -------GPSGAPGEDGRPGPPGPQGARGQPGVMG 534
Score = 78.2 bits (191), Expect = 2e-14
Identities = 140/520 (26%), Positives = 183/520 (35%), Gaps = 105/520 (20%)
Query: 3 EAAEP----EGVAPGPQGPPEVPAPLAERPGEPGAAGGEA----EGPEGSEGAEEAPRGA 54
EA +P E PGPQG P PG PG G +G +G GA +
Sbjct: 187 EAGKPGKAGERGPPGPQGARGFPGT----PGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 242
Query: 55 AAVKEAGGGGP--------DRGPEAEARGTRGAHG-ETEAEEGAPEGAEVPQGGEETSGA 105
+ E G GP +RG A G GA G + + P G P GG GA
Sbjct: 243 GSPGENGSPGPMGPRGLPGERGRTGPA-GAAGARGNDGQPGPAGPPGPVGPAGGPGFPGA 301
Query: 106 QQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSV-DAEG 164
GA+GE R PE + P R E P G++ D + A+G
Sbjct: 302 P---------GAKGEAGPTGARGPEGAQGP-RGEPGTPGSPGPAGASGNPGTDGIPGAKG 351
Query: 165 PLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQA-----------E 213
G A G AG A G G GP G A GPLG Q +
Sbjct: 352 SAG----APGIAG----APGFPG----PRGPPGPQ-GATGPLGPKGQTGEPGIAGFKGEQ 398
Query: 214 GPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAG--DPAGDGVEAGVPAGDSVE 271
GP G+ G G A GPAG+ EG+ G E G P G E G P
Sbjct: 399 GPKGE----PGPAGPQ-GAPGPAGE----EGKRGARGEPGGVGPIGPPGERGAPGNRGFP 449
Query: 272 AE----GPAGDSMDAEGPAGRA--RRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGE 325
+ GP G + GP+G A + +G+P + G+ L P A + G++ +
Sbjct: 450 GQDGLAGPKG-APGERGPSGLAGPKGANGDPGRPGEPGL-PGARGLTGRPGDAGPQGKVG 507
Query: 326 LAWDAAEEAEVPGVKGSEEAA--------PGDARADAGEDRVGD-------GPQQEPGED 370
+ E+ PG G + A PG A+ + G+ G + PG+D
Sbjct: 508 PSGAPGEDGR-PGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKD 566
Query: 371 EERRERSPEGPREEEAAGGEEESPDSS-------PHGEASRGAAEPEAQLSNHLAEEGPA 423
E P GP GE+ +P S P G G + + G
Sbjct: 567 GETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLV 626
Query: 424 EGSGEAARVNGRREDGEASEPRALGQEHDITLFVKAGYDG 463
GE R GE P A G + L G DG
Sbjct: 627 GPRGE------RGFPGERGSPGAQGLQGPRGLPGTPGTDG 660
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 97.8 bits (242), Expect = 3e-20
Identities = 130/432 (30%), Positives = 163/432 (37%), Gaps = 66/432 (15%)
Query: 7 PEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPD 66
P G+ PG +G P P P R G GA G A GP G G P AV G GP
Sbjct: 303 PRGL-PGERGRPGAPGPAGAR-GNDGATG--AAGPPGPTGPAGPPGFPGAVGAKGEAGP- 357
Query: 67 RGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGA--SPG-RGAQGEPRG 123
+GP + G +G GE P GA P G G +GA +PG GA G P
Sbjct: 358 QGPRG-SEGPQGVRGEPGPP--GPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGA 414
Query: 124 EAQREPEDSAAPERQEEAEQRPEVP----EGSASGEAGDSVDAEGPLGDNIEAEGPAGDS 179
P+ P + P P + A GE G V +GP GPAG+
Sbjct: 415 RGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPG-PVGVQGP-------PGPAGE- 465
Query: 180 VEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSV-DAEGRVGDSVDAEGPAGD 238
EG+ G + GP G GP G+ GP A+G G +GPAG+
Sbjct: 466 ---EGKRG-ARGEPGPTG----LPGPPGER---GGPGSRGFPGADGVAG----PKGPAGE 510
Query: 239 --SVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEP 296
S G G EAG P G+ S + GP G + GPAG+ G P
Sbjct: 511 RGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKT-GPPGPAGQ----DGRP 565
Query: 297 QQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGE 356
G QA + + A PG+ A E VPG G+ A D A A
Sbjct: 566 GPPGPPGARGQAGVMGFPGPKGAAGEPGK-----AGERGVPGPPGAVGPAGKDGEAGA-- 618
Query: 357 DRVGDGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNH 416
GP G ER E+ P G + G + + P GEA + E +
Sbjct: 619 ----QGPPGPAGPAGERGEQGPAG-----SPGFQGLPGPAGPPGEAGKPG---EQGVPGD 666
Query: 417 LAEEGPAEGSGE 428
L GP+ GE
Sbjct: 667 LGAPGPSGARGE 678
Score = 94.7 bits (234), Expect = 2e-19
Identities = 139/480 (28%), Positives = 181/480 (37%), Gaps = 72/480 (15%)
Query: 12 PGPQGPPEVPAPLAER--PGE---PGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPD 66
PGP GPP E+ PG+ PG +G E E + P G A + A G +
Sbjct: 646 PGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGN 705
Query: 67 RGPEAEARGTRGAHGETEAEEGAP--EGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGE 124
G + +A G GA G +GAP +G +G G + G + +GA G P +
Sbjct: 706 DGAKGDA-GAPGAPG----SQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKD 760
Query: 125 AQR-------EPEDSAAP-ERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPA 176
R P + AP ++ E P P G A G GD + GP G A P
Sbjct: 761 GVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTG-ARGAPGDRGE-PGPPGPAGFAGPPG 818
Query: 177 GDSVE-AEGRVGDS-----VDAEGPAGDSVDAEGPLGDNIQAEGPAG--DSVDAEGRVG- 227
D A+G GD+ GPAG + GP+G N+ A G G S G G
Sbjct: 819 ADGQPGAKGEPGDAGAKGDAGPPGPAGPA-GPPGPIG-NVGAPGAKGARGSAGPPGATGF 876
Query: 228 ----DSVDAEGPAGDS--------VDAEGRVGDSVEAGDPAGDGVEAGV-----PAGD-- 268
V GP+G++ EG G E G PAG E G PAG+
Sbjct: 877 PGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETG-PAGRPGEVGPPGPPGPAGEKG 935
Query: 269 SVEAEGPAGDSMDAEGPAGRA--RRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGEL 326
S A+GPAG + GP G A R V G P Q G+ + +GE + P
Sbjct: 936 SPGADGPAG-APGTPGPQGIAGQRGVVGLPGQRGERGF----PGLPGPSGEPGKQGPS-- 988
Query: 327 AWDAAEEAEVPGVKGSEEAA--PGDARADAGEDRVGD-GPQQEPGEDEERRERSPEGPRE 383
A+ E PG G A PG++ + G G PG +R E P GP
Sbjct: 989 --GASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPG 1046
Query: 384 EEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASE 443
A G P G A + E + GP G A R + GE E
Sbjct: 1047 APGAPGA-----PGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGE 1101
Score = 94.4 bits (233), Expect = 3e-19
Identities = 145/505 (28%), Positives = 186/505 (36%), Gaps = 76/505 (15%)
Query: 3 EAAEPEGVAP-GPQGPPEVPAPLAERPGEPGAAGGEAE-GPEGSEGAEEAP--------- 51
E EP P GP+GPP P + GE G G E GP G +GA P
Sbjct: 207 EPGEPGASGPMGPRGPPGPPGKNGD-DGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMK 265
Query: 52 --RGAAAVKEAGGGGPDRGPEAE--ARGTRGAHGET-----EAEEGAPEGAEVPQGGEET 102
RG + + A G GP+ E + G GA G+ E G P GA P G
Sbjct: 266 GHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRP-GAPGPAGARGN 324
Query: 103 SGAQQVEGASPGRGAQGEP--------RGEAQRE-PEDSAAPERQEEAEQRPEVPEGSAS 153
GA G G G P +GEA + P S P+ E P P G+A
Sbjct: 325 DGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVR-GEPGPPGPAGAAG 383
Query: 154 GEAGDSVDAE-GPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDA--EGPLGDNI 210
D + G G N A G AG A G G A GP+G GP G++
Sbjct: 384 PAGNPGADGQPGAKGAN-GAPGIAG----APGFPG----ARGPSGPQGPGGPPGPKGNSG 434
Query: 211 Q--AEGPAGDSVDAEGRVGDSVDAEGPAGDSVD-----AEGRVGDSVEAGDPA--GDGVE 261
+ A G GD+ A+G G V +GP G + + A G G + G P G
Sbjct: 435 EPGAPGSKGDT-GAKGEPGP-VGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGS 492
Query: 262 AGVPAGDSVEA-EGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAG 320
G P D V +GPAG+ + GPAG G P ++G P + A G +
Sbjct: 493 RGFPGADGVAGPKGPAGER-GSPGPAGP----KGSPGEAG----RPGEAGLPGAKGLTG- 542
Query: 321 RSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVG-DGPQQEPGEDEERRERSPE 379
SPG D P + PG A +G GP+ GE + ER
Sbjct: 543 -SPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVP 601
Query: 380 GPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDG 439
GP G++ GEA A + E+GPA G G
Sbjct: 602 GPPGAVGPAGKD--------GEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPG 653
Query: 440 EASEPRALGQEHDITLFVKAGYDGE 464
EA +P G D+ +G GE
Sbjct: 654 EAGKPGEQGVPGDLGAPGPSGARGE 678
Score = 93.2 bits (230), Expect = 7e-19
Identities = 144/475 (30%), Positives = 175/475 (36%), Gaps = 111/475 (23%)
Query: 12 PGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEA 71
PG GPP P P PG PG G A P+ S G +E G +V GP GP
Sbjct: 138 PGLPGPPGPPGP----PGPPGLGGNFA--PQLSYGYDEKSTGGISVP-----GP-MGPS- 184
Query: 72 EARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQREPED 131
G RG G P GA PQG + G GAS G +G P G + +D
Sbjct: 185 ---GPRGLPG--------PPGAPGPQGFQGPPGEPGEPGASGPMGPRGPP-GPPGKNGDD 232
Query: 132 SAAPERQEEAEQRPEVPEGSA-----------------SGEAGDSVDAEGPLGDNIEAEG 174
A + E+ P P+G+ SG G DA GP G E
Sbjct: 233 GEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDA-GPAGPKGEPGS 291
Query: 175 PAGDSVEAEGRVG--------DSVDAEGPAG-----DSVDAEGPLGDNIQAEGPAG---- 217
P + A G++G A GPAG + A GP G GPAG
Sbjct: 292 PGENG--APGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPT----GPAGPPGF 345
Query: 218 -DSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPA 276
+V A+G G +GP G +EG G E G P PAG A GPA
Sbjct: 346 PGAVGAKGEAG----PQGPRG----SEGPQGVRGEPGPPG--------PAG----AAGPA 385
Query: 277 GDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEV 336
G+ A+G G A+ +G P +G A A G S + PG E
Sbjct: 386 GNP-GADGQPG-AKGANGAPGIAG-------APGFPGARGPSGPQGPGGPPGPKGNSGE- 435
Query: 337 PGVKGSEEAAPGDARADAGEDRVG-DGPQQEPGEDEERRERSPEGPREEEAAGGEEESPD 395
PG GS+ GD A VG GP GE+ +R R GP GE P
Sbjct: 436 PGAPGSK----GDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPG 491
Query: 396 SS--PHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRALG 448
S P + G P + + GP GEA R GEA P A G
Sbjct: 492 SRGFPGADGVAGPKGPAGERGSP-GPAGPKGSPGEAGR------PGEAGLPGAKG 539
Score = 86.7 bits (213), Expect = 7e-17
Identities = 134/443 (30%), Positives = 162/443 (36%), Gaps = 86/443 (19%)
Query: 5 AEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGE-AEGPEGSEGAEEAPRGAAAVKEAGGG 63
A+ + PGP GP P P+ G PGA G + GP G+ G A +G
Sbjct: 834 AKGDAGPPGPAGPAGPPGPIG-NVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNA 892
Query: 64 GPDRGP-EAEARGTRGAHGET-----------------EAEEGAPEGAEVPQGGEETSGA 105
GP P A G +G GET E+G+P GA+ P G T G
Sbjct: 893 GPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSP-GADGPAGAPGTPGP 951
Query: 106 QQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGP 165
Q + G RG G P +R P E +Q P ASGE G GP
Sbjct: 952 QGIAGQ---RGVVGLPGQRGERGFPGLPGPS-GEPGKQGP----SGASGERG----PPGP 999
Query: 166 LGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAG--DSVDAEGPLGDNIQAEGPAGDSVDAE 223
+G A GP G+S GR G + AEG G S A+G G+ GPAG A
Sbjct: 1000 MGPPGLA-GPPGES----GREG-APGAEGSPGRDGSPGAKGDRGET----GPAGPP-GAP 1048
Query: 224 GRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAE 283
G G A GP G + G+ GD E G PAG G P G A GPAG +
Sbjct: 1049 GAPG----APGPVGPA----GKSGDRGETG-PAGPAGPVG-PVG----ARGPAG----PQ 1090
Query: 284 GPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAE----------E 333
GP G GE + GD + + SPGE A
Sbjct: 1091 GPRGD----KGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGS 1146
Query: 334 AEVPGVKGSEEAAPGDARADAGEDRVGD-GPQQEPGEDEERRERSPEGPREEEAAGGEEE 392
A PG K PG R GD GP PG P GP +AG +
Sbjct: 1147 AGAPG-KDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPP------GPPGPPGPPSAGFDFS 1199
Query: 393 SPDSSPHGEASRGAAEPEAQLSN 415
P +A G A +N
Sbjct: 1200 FLPQPPQEKAHDGGRYYRADDAN 1222
Score = 81.6 bits (200), Expect = 2e-15
Identities = 127/475 (26%), Positives = 164/475 (34%), Gaps = 68/475 (14%)
Query: 5 AEPEGV--APGPQGPPEVPAPLAERPGEPGAAGGEAE----GPEGSEGAEEAPRGAAAVK 58
A P+G +PG G + P+ PG GA G + E GP G GA AP
Sbjct: 748 AGPKGADGSPGKDGVRGLTGPIGP-PGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPG 806
Query: 59 EAGGGGPDRGPEAEAR-GTRGAHGETEAE-EGAPEGAEVPQGGEETSGAQQVEGASPGRG 116
G G P A+ + G +G G+ A+ + P G P G G GA RG
Sbjct: 807 PPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARG 866
Query: 117 AQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPA 176
+ G P P P P G A E G +GP G+ GPA
Sbjct: 867 SAGPPGATGFPGAAGRVGPPGPS-GNAGPPGPPGPAGKEGG-----KGPRGET----GPA 916
Query: 177 GDSVEAEGRVGDSVDAEGPAGD--SVDAEGPLGDNIQAEGPAGDS-----VDAEGRVGDS 229
G G VG GPAG+ S A+GP G GP G + V G+ G+
Sbjct: 917 G----RPGEVGPP-GPPGPAGEKGSPGADGPAGAP-GTPGPQGIAGQRGVVGLPGQRGER 970
Query: 230 --VDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEA-GVPAGDSVEAEGPAGDSMDAEGPA 286
GP+G+ +G G S E G P G P G+S P AEG
Sbjct: 971 GFPGLPGPSGEP-GKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPG-----AEGSP 1024
Query: 287 GRARRVSGEPQQSGD-GSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEA 345
GR G P GD G P A G P A + + E +
Sbjct: 1025 GR----DGSPGAKGDRGETGPAGPP--GAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPV 1078
Query: 346 APGDARADAGEDRVGDGPQQEPGEDEERRERS----------------PEGPREEEAAGG 389
P AR AG GP+ + GE E+ +R P P E+ +G
Sbjct: 1079 GPVGARGPAGPQ----GPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGA 1134
Query: 390 EEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEP 444
+ P G A + L + GP +G+A V G P
Sbjct: 1135 SGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPP 1189
Score = 55.1 bits (131), Expect = 2e-07
Identities = 88/331 (26%), Positives = 113/331 (34%), Gaps = 46/331 (13%)
Query: 140 EAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDS 199
E E P P+GS S ++ EGP GD GP G A D + +
Sbjct: 88 EGECCPVCPDGSESPTDQETTGVEGPKGDT----GPRGPRGPAGPPGRDGIPGQPGLPGP 143
Query: 200 VDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDG 259
GP GP G + ++ D + G SV G +G S G P G
Sbjct: 144 PGPPGP-------PGPPGLGGNFAPQLSYGYDEKSTGGISV--PGPMGPSGPRGLPGPPG 194
Query: 260 VEAGVPAGDSVEAEGPAGDSMD--AEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGE 317
A P G +GP G+ + A GP G R G P ++GD EA +
Sbjct: 195 --APGPQG----FQGPPGEPGEPGASGPMG-PRGPPGPPGKNGD-----DGEAGKPGRPG 242
Query: 318 SAGRSPGELAWDAAEEAEVPGVKGSE-----EAAPGDARADAGEDRVGD----------G 362
G + A A +PG+KG + A GDA + G G
Sbjct: 243 ERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMG 302
Query: 363 PQQEPGEDEERRERSPEGPREEEAAGGEEESP----DSSPHGEASRGAAEPEAQLSNHLA 418
P+ PGE P G R + A G P + P G A+ EA
Sbjct: 303 PRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRG 362
Query: 419 EEGPAEGSGEAARVNGRREDGEASEPRALGQ 449
EGP GE G A P A GQ
Sbjct: 363 SEGPQGVRGEPGPPGPAGAAGPAGNPGADGQ 393
>gi|48762934 alpha 2 type I collagen [Homo sapiens]
Length = 1366
Score = 95.1 bits (235), Expect = 2e-19
Identities = 138/461 (29%), Positives = 176/461 (38%), Gaps = 73/461 (15%)
Query: 11 APGPQGPPEVPAPLAERP--------GEPGAAGGEAE----------GPEGSEG--AEEA 50
APG GP +P P+ GEPG AG + E GP+G G EE
Sbjct: 320 APGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEG 379
Query: 51 PRGAAAVKEAGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEG 110
RG EAG GP P RG+ G+ G A+ A G P G SG V G
Sbjct: 380 KRGPNG--EAGSAGPPGPP--GLRGSPGSRGLPGADGRA--GVMGPPGSRGASGPAGVRG 433
Query: 111 ASPGRGAQGE-----PRG----EAQREPEDSAAPERQEEAEQRP-EVPEGSASGEAGDSV 160
+ G GE PRG P P + RP + A GE G ++
Sbjct: 434 PNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPG-NI 492
Query: 161 DAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSV 220
GP +GP GD G+ GD A G AG + A GP G+N A+GP G
Sbjct: 493 GFPGP-------KGPTGD----PGKNGDKGHA-GLAG-ARGAPGPDGNN-GAQGPPGPQ- 537
Query: 221 DAEGRVGDSVDAEGPAGDS--VDAEGRVGDSVEAGDPAGDGV--EAGVPAGDSVEAE-GP 275
+G G+ +GP G G G + E G P G+ E G+P E GP
Sbjct: 538 GVQGGKGE----QGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGP 593
Query: 276 AGDSMDAEGPAG--RARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGE-----LAW 328
G+S A GP G +R SG P G+ A+ A PGE +
Sbjct: 594 PGES-GAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPG 652
Query: 329 DAAEEAEVPGVKGSEEAAPGDARADAGEDRVG-DGPQQEPGEDEERRERSPEGPREEEAA 387
E+ E PG++G E PG A VG GP G+ E P GP +
Sbjct: 653 GKGEKGE-PGLRG-EIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGS 710
Query: 388 GGEE-ESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSG 427
GE E + P+G A A + +GP +G
Sbjct: 711 PGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENG 751
Score = 83.6 bits (205), Expect = 6e-16
Identities = 153/540 (28%), Positives = 188/540 (34%), Gaps = 133/540 (24%)
Query: 6 EPEGVA-PGPQGPPEVPAPLAERPGEPGAAGGE-AEGPEGSEGAE--EAPRGAAAVK-EA 60
EP + PGP+GP P ++ G G AG A GP+G+ GA+ P+G K E
Sbjct: 488 EPGNIGFPGPKGPTGDPGKNGDK-GHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQ 546
Query: 61 GGGGP--------DRGPEAEA--RGTRGAHGE--------TEAEEGAP------------ 90
G GP GP E G RG HGE E G P
Sbjct: 547 GPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPI 606
Query: 91 -----------------------EGAEVPQGGEETSGAQQVEGASPGRGAQGEP--RGEA 125
G P G G + G G+G +GEP RGE
Sbjct: 607 GSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEI 666
Query: 126 QREPEDSA--AP-------------ERQEEAEQRPEVPEG--SASGEAGDSVDAEGPLGD 168
D A AP +R E P P G + GE G+ GP G
Sbjct: 667 GNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGE----VGPAGP 722
Query: 169 NIEAEGPAGDSVE--AEGRVGDSVDAEGPAGDS--VDAEGPLGDNIQAEGPAGDSVDAEG 224
N A GPAG + + A+G G A+GP G++ V GP+G A GPAG + G
Sbjct: 723 NGFA-GPAGAAGQPGAKGERG----AKGPKGENGVVGPTGPVG----AAGPAGPN-GPPG 772
Query: 225 RVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEA--GVPAGDSVEA-EGPAGDSMD 281
G D GP G G G + G P G+ G P E GP GD
Sbjct: 773 PAGSRGDG-GPPG----MTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGD--- 824
Query: 282 AEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAG-----RSPGELAWDAAE-EAE 335
+GP GR V G P EA + G +PG L + E
Sbjct: 825 -QGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERG 883
Query: 336 VPGVKGSEE-------AAPGDARADAGEDRVG----DGPQQEPGEDEERRERSPEGPREE 384
+PGV G+ A P AR G VG +G E G D P G +
Sbjct: 884 LPGVAGAVGEPGPLGIAGPPGARGPPG--AVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQ 941
Query: 385 EAAGGEEESPDS-SPHGEAS----RGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDG 439
GE P + P G A G P + N E GP+ G A V R G
Sbjct: 942 PGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNR-GETGPSGPVGPAGAVGPRGPSG 1000
Score = 80.5 bits (197), Expect = 5e-15
Identities = 146/522 (27%), Positives = 186/522 (35%), Gaps = 103/522 (19%)
Query: 12 PGPQGPPEVPAPLAERPGEPGAAG--GEAEGPEGSEG-----AEEAPRG-AAAVKEAGGG 63
PG +G P P R G G+ G G A GP GS G P+G AV AG
Sbjct: 219 PGERGRVGAPGPAGAR-GSDGSVGPVGPA-GPIGSAGPPGFPGAPGPKGEIGAVGNAGPA 276
Query: 64 GPDRGPEAEA-----------RGTRGAHGETEAE--EGAPEGAEVP--QGGEETSGAQQV 108
GP GP E G GA+G T A+ G P A P G G
Sbjct: 277 GP-AGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGA 335
Query: 109 EGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEG-----SASGEAGDSVDAE 163
GA+ RG GEP G A + E E Q P P G +GEAG S
Sbjct: 336 AGATGARGLVGEP-GPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAG-SAGPP 393
Query: 164 GPLGDNIEAEGPAGDSVEAEGRVG-----DSVDAEGPAGDSVDAEGPLGD---------- 208
GP G + + A+GR G S A GPAG GP GD
Sbjct: 394 GPPG--LRGSPGSRGLPGADGRAGVMGPPGSRGASGPAG----VRGPNGDAGRPGEPGLM 447
Query: 209 ----------NIQAEGPAGDSVDAEGRVG-DSVDAE----GPAGDSVDAE--GRVGDSVE 251
NI GPAG EG VG +D GPAG + G G
Sbjct: 448 GPRGLPGSPGNI---GPAG----KEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGP 500
Query: 252 AGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAI 311
GDP +G + + A GP G++ A+GP G G+ +Q G P + +
Sbjct: 501 TGDPGKNGDKGHAGLAGARGAPGPDGNN-GAQGPPGPQGVQGGKGEQGPPG--PPGFQGL 557
Query: 312 EVAAGESAG-RSPGELAWDAAEEAEVPGVKG--SEEAAPGDARADAGEDRVGD-GPQQEP 367
+G + PGE E +PG G E PG++ A +G GP P
Sbjct: 558 PGPSGPAGEVGKPGERGLHG--EFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPP 615
Query: 368 GEDEERRE---------RSPEGPR----EEEAA---GGEEESPDSSPHGEASRGAAEPEA 411
G D + E P GP E AA GG+ E + GE +
Sbjct: 616 GPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGAR 675
Query: 412 QLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRALGQEHDI 453
+ GPA +G+ G A + G+ ++
Sbjct: 676 GAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEV 717
Score = 79.7 bits (195), Expect = 8e-15
Identities = 141/491 (28%), Positives = 179/491 (36%), Gaps = 80/491 (16%)
Query: 9 GVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRG 68
G+ PGP G L G PGAAG A GP+G +G P AG GP G
Sbjct: 87 GLGPGPMG-------LMGPRGPPGAAG--APGPQGFQGPAGEPGEPGQTGPAGARGP-AG 136
Query: 69 PEAEARGTRGAHGE--TEAEEG--APEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGE 124
P +A G G G+ E G P+GA G G + + G + G +G+P
Sbjct: 137 PPGKA-GEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQP--- 192
Query: 125 AQREPEDSAAPERQEEAEQRPEVP-EGSASGEAGDSVDAEGPLGD--NIEAEGPAGDSVE 181
AP + E P P E G+ G A G G+ + A GPAG
Sbjct: 193 --------GAPGVKGE----PGAPGENGTPGQTG----ARGLPGERGRVGAPGPAG---- 232
Query: 182 AEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVD 241
A G G SV GPAG + + GP G A GP G+ + A G G + A GP G+ V
Sbjct: 233 ARGSDG-SVGPVGPAG-PIGSAGPPGFP-GAPGPKGE-IGAVGNAGPAGPA-GPRGE-VG 286
Query: 242 AEGRVGDSVEAGDPAGDGV-----EAGVP-AGDSVEAEGPAG--DSMDAEGPAGRARRVS 293
G G G+P +G+ AG+P + GP G + A G G AR +
Sbjct: 287 LPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATG-ARGLV 345
Query: 294 GEPQQSGD----------GSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSE 343
GEP +G GS PQ +GE R P A A PG++GS
Sbjct: 346 GEPGPAGSKGESGNKGEPGSAGPQGP--PGPSGEEGKRGPNGEAGSAGPPGP-PGLRGS- 401
Query: 344 EAAPGDARADAGEDRVG-DGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHGEA 402
PG + R G GP G R P G G P P
Sbjct: 402 ---PGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPG-LMGPRGLPGSPG 457
Query: 403 SRGAAEPEAQ-----LSNHLAEEGPAEGSGEAARVNGRREDGEASEPRALGQEHDITLFV 457
+ G A E + GPA GE + G +P G + L
Sbjct: 458 NIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAG 517
Query: 458 KAGYDGESIGN 468
G G N
Sbjct: 518 ARGAPGPDGNN 528
Score = 72.8 bits (177), Expect = 1e-12
Identities = 135/493 (27%), Positives = 168/493 (34%), Gaps = 88/493 (17%)
Query: 3 EAAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAE----GPEGSEGAEEAP--RGAAA 56
E EP P P P A G PG G E GP+G+ G P G
Sbjct: 119 EPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKG 178
Query: 57 VKEAGG--------GGPDRGPEAEARGTRGAHGETEAE----EGAPEGAEVPQGGEETSG 104
++ G G P E A G G G+T A E GA P G + G
Sbjct: 179 IRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDG 238
Query: 105 AQQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEG 164
+ G + G+ G P P+ E P P G GE G G
Sbjct: 239 SVGPVGPAGPIGSAGPPGFPGAPGPKG----EIGAVGNAGPAGPAG-PRGEVG-LPGLSG 292
Query: 165 PLG--DNIEAEGPAGDSVEAEGRVG-----DSVDAEGPAG--DSVDAEGPLGDN--IQAE 213
P+G N A G G A+G G + GP G V A G G +
Sbjct: 293 PVGPPGNPGANGLTG----AKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEP 348
Query: 214 GPAGDSVDAEGRVGD--SVDAEGPAGDSVD--AEGRVGDSVEAGDPAGDGVEA-----GV 264
GPAG S G G+ S +GP G S + G G++ AG P G+ G+
Sbjct: 349 GPAG-SKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGL 407
Query: 265 PAGD----------SVEAEGPAGDSMDAEGPAGRARRVSGEPQQSG-------DGSLSPQ 307
P D S A GPAG GP G A R GEP G G++ P
Sbjct: 408 PGADGRAGVMGPPGSRGASGPAG----VRGPNGDAGR-PGEPGLMGPRGLPGSPGNIGPA 462
Query: 308 AEAIEVAAGESAGRSPGEL--AWDAAEEAEV--PGVKGSEEAAPGDARADAGEDRVG-DG 362
+ V GR PG + A E + PG KG GD + + G G
Sbjct: 463 GKEGPVGLPGIDGR-PGPIGPAGARGEPGNIGFPGPKG----PTGDPGKNGDKGHAGLAG 517
Query: 363 PQQEPGEDEERRERSPEGPREEEAAGGEEESPD-------SSPHGEASRGAAEPEAQLSN 415
+ PG D + P GP+ + GE+ P P G A E L
Sbjct: 518 ARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHG 577
Query: 416 HLAEEGPAEGSGE 428
GPA GE
Sbjct: 578 EFGLPGPAGPRGE 590
Score = 55.8 bits (133), Expect = 1e-07
Identities = 127/476 (26%), Positives = 154/476 (32%), Gaps = 116/476 (24%)
Query: 2 AEAAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAE-GPEGSEGAEEAPRGAAAVKEA 60
A+ + E GP GP P A G PG AG + GP G G A +
Sbjct: 743 AKGPKGENGVVGPTGPVGAAGP-AGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPS 801
Query: 61 GGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGE 120
G GP GP A G G G P G + P G GA PG +
Sbjct: 802 GISGPP-GPPGPA-GKEGLRG--------PRGDQGPVGRTGEVGAV----GPPGFAGEKG 847
Query: 121 PRGEA-QREPEDSAAPERQEEAEQRPEVP----EGSASGEAGDSVDAEGPLGDNIEAEGP 175
P GEA P + P+ A +P E G AG +V GPLG GP
Sbjct: 848 PSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAG-AVGEPGPLG----IAGP 902
Query: 176 AGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGP 235
G A GP G A G G N A G AG +G G+ +GP
Sbjct: 903 PG--------------ARGPPG----AVGSPGVN-GAPGEAG----RDGNPGN----DGP 935
Query: 236 AGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGE 295
G +G+ G E G P G P G + A GP GP G A +
Sbjct: 936 PG----RDGQPGHKGERGYPGNIG-----PVG-AAGAPGP-------HGPVGPAGKHGNR 978
Query: 296 PQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAE-----VPGVKGSE--EAAPG 348
+ G + P A G P + D E E +PG+KG + PG
Sbjct: 979 GETGPSGPVGPAG-----AVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPG 1033
Query: 349 DARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHGEASRGAAE 408
A G Q PG R P GP G P G
Sbjct: 1034 IAG--------HHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHP----------GTVG 1075
Query: 409 PEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRALGQEHDITLFVKAGYDGE 464
P A + +GPA G G P G +D GYDG+
Sbjct: 1076 P-AGIRGPQGHQGPAGPPG---------PPGPPGPPGVSGGGYDF------GYDGD 1115
Score = 32.7 bits (73), Expect = 1.1
Identities = 39/141 (27%), Positives = 47/141 (33%), Gaps = 13/141 (9%)
Query: 273 EGPAGDSMDAEGPAGRARRVSGEPQQSG-DGSLSPQAEAIEVAAGESAGRSPGELAWDAA 331
+GPAGD GP G R G P + G DG P G + +D
Sbjct: 32 KGPAGD----RGPRGE-RGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQ--YDGK 84
Query: 332 EEAEVPGVKG--SEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAAGG 389
PG G PG A A + GP EPGE + GP G
Sbjct: 85 GVGLGPGPMGLMGPRGPPGAAGAPGPQGF--QGPAGEPGEPGQTGPAGARGPAGPPGKAG 142
Query: 390 EEESPDSSPHGEASRGAAEPE 410
E+ P P RG P+
Sbjct: 143 EDGHP-GKPGRPGERGVVGPQ 162
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 90.5 bits (223), Expect = 5e-18
Identities = 131/473 (27%), Positives = 174/473 (36%), Gaps = 54/473 (11%)
Query: 11 APGPQGP--PEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRG 68
APG GP P+ P+ L PGE G G GP G+ G P + V GP
Sbjct: 2190 APGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLV------GPQGS 2243
Query: 69 PEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQRE 128
P G G GET + GAP G + G + G+ V G SPG P+G E
Sbjct: 2244 P-----GLPGQVGET-GKPGAP-GRDGASGKDGDRGSPGVPG-SPGLPGPVGPKG----E 2291
Query: 129 PEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGD 188
P + AP + + +G+ G AGD V G GD GP G+ EA GR G+
Sbjct: 2292 PGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDR-GLPGPRGEKGEA-GRAGE 2349
Query: 189 SVD--------AEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSV 240
D A GP G D + + GP G +G +G + A V
Sbjct: 2350 PGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPG----VKGDLG--LPGLPGAPGVV 2403
Query: 241 DAEGRVGDSVEAGDPAGDGVE--AGVPAGDSVEAE-GPAGDSMDAEGPAGRARRVSGEPQ 297
G+ G E G P G AG P + + GP G + GP G A + G+
Sbjct: 2404 GFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPP-GSVGPPG-ASGLKGDKG 2461
Query: 298 QSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDA-----RA 352
G G P+ E E GR PG+ + P E GD +
Sbjct: 2462 DPGVGLPGPRGERGEPGIRGEDGR-PGQ---EGPRGLTGPPGSRGERGEKGDVGSAGLKG 2517
Query: 353 DAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAAGGEEESP-DSSPHGEASRGAAEPEA 411
D G+ V GP G + ER P G ++ G+ P D GE +
Sbjct: 2518 DKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLP 2577
Query: 412 QLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRALGQEHDITLFVKAGYDGE 464
L L +G +G +DG P G++ D+ G GE
Sbjct: 2578 GLRGLLGPQGQPGAAGIPGDPGSPGKDG---VPGIRGEKGDVGFMGPRGLKGE 2627
Score = 89.0 bits (219), Expect = 1e-17
Identities = 139/488 (28%), Positives = 170/488 (34%), Gaps = 104/488 (21%)
Query: 11 APGPQGPPEVPAPLAERPGEPGAAGGE-AEGPEGSEGAEEAP--RGAAAVKEAGGGGPDR 67
APGPQGPP ER G PGA G + G G+ G AP +G+ + G +R
Sbjct: 1282 APGPQGPPGSATAKGER-GFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGER 1340
Query: 68 GPEAEARGTRGAHGETEAEEG----------APEGAEVPQGGEETSGAQQVEGASPGRGA 117
GP +G GA G+ EG P G P+G G + G PG
Sbjct: 1341 GPRG-PKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGL-PGTAM 1398
Query: 118 QGEPRGEAQREP----EDSAAPERQ-------EEAEQRPEVPEGSASGEAGDSVDAEGPL 166
+G+ +R P E AP Q P P G GE GDS D L
Sbjct: 1399 KGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGK-KGEKGDSEDGAPGL 1457
Query: 167 GDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQ-----AEGPAGDS-- 219
+ G G G G A GP GD GPLG+ + GPAG
Sbjct: 1458 PGQPGSPGEQG----PRGPPG----AIGPKGDR-GFPGPLGEAGEKGERGPPGPAGSRGL 1508
Query: 220 VDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPA-------------GDGVEAGVPA 266
GR G + EGP G + +G G+ GDPA GD AG
Sbjct: 1509 PGVAGRPG-AKGPEGPPGPT-GRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRG 1566
Query: 267 GDSVEAE------------GPAGDSMDAEGPAGRARRV-----SGEPQQSGD-------G 302
V+ E GP GD D GP G R SG P + GD G
Sbjct: 1567 ATGVQGERGPPGLVLPGDPGPKGDPGD-RGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPG 1625
Query: 303 SLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSE--EAAPGDARADAGEDRVG 360
+ P+ EV GE P + +PG G APG R GE
Sbjct: 1626 PVGPRGRDGEV--GEKGDEGP-------PGDPGLPGKAGERGLRGAPG-VRGPVGE---- 1671
Query: 361 DGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEE 420
G Q +PGED GP+ + E P P G E +E
Sbjct: 1672 KGDQGDPGEDGRNGSPGSSGPKGDRG----EPGPPGPPGRLVDTGPGAREKGEPGDRGQE 1727
Query: 421 GPAEGSGE 428
GP G+
Sbjct: 1728 GPRGPKGD 1735
Score = 84.7 bits (208), Expect = 3e-16
Identities = 136/479 (28%), Positives = 176/479 (36%), Gaps = 106/479 (22%)
Query: 11 APGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPE 70
+PGP GPP V L PG PGA G G G G PRG E G GP
Sbjct: 2378 SPGPPGPPGVKGDLG-LPGLPGAPG--VVGFPGQTG----PRG-----EMGQPGPS---- 2421
Query: 71 AEARGTRGAHGETEAEE-GAPEGAEVPQGGEETSGAQQVEG--ASPG------RGAQGEP 121
G RG G E P G P G GA ++G PG RG +GEP
Sbjct: 2422 ----GERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEP 2477
Query: 122 --RGEAQREPED-----SAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEG 174
RGE R ++ + P + E ++ +V G+ GDS GP G
Sbjct: 2478 GIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGP-------PG 2530
Query: 175 PAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEG 234
P G A+G +G+ GP G D +GP GDN G GD ++G GD A
Sbjct: 2531 PRG----AKGDMGE----RGPRGLDGD-KGPRGDN----GDPGDK-GSKGEPGDKGSAGL 2576
Query: 235 PA-GDSVDAEGRVGDSVEAGDPAGDGVEAGVPA-----GD-----------------SVE 271
P + +G+ G + GDP G + GVP GD +
Sbjct: 2577 PGLRGLLGPQGQPGAAGIPGDPGSPGKD-GVPGIRGEKGDVGFMGPRGLKGERGVKGACG 2635
Query: 272 AEGPAGDSMDAEGPAGRA-----RRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGEL 326
+G GD +A GP GR + GEP G + I PG
Sbjct: 2636 LDGEKGDKGEA-GPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPK 2694
Query: 327 AWDAAEEAE--VPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREE 384
D E+ E PG+ G + D A GP+ G ++ ER P G R
Sbjct: 2695 G-DQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVV 2753
Query: 385 EAAG--------GEEESP-DSSPHGEASRGAAEPE-------AQLSNHLAEEGPAEGSG 427
A G GE+ P + P GE A + ++S H A +G SG
Sbjct: 2754 GAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQEMSQHCACQGQFIASG 2812
Score = 84.3 bits (207), Expect = 3e-16
Identities = 123/403 (30%), Positives = 163/403 (40%), Gaps = 65/403 (16%)
Query: 12 PGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEA 71
PGPQGPP + L ER G PG +G G G G P A V EAG G +RG
Sbjct: 2011 PGPQGPPGL--ALGER-GPPGPSG--LAGEPGKPGIPGLPGRAGGVGEAGRPG-ERGERG 2064
Query: 72 EARGTRGAHGE--------TEAEEGAP-EGAEVPQGGEETSGAQQVEGASPGRGAQGEPR 122
E +G RG G T G P V + G SG Q G +GA+GEP
Sbjct: 2065 E-KGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGL---KGAKGEPG 2120
Query: 123 GEAQREPE-DSAAPE-RQEEAEQRPEVPEGSAS--GEAG-----DSVDAEGPLGDNIEAE 173
+ P+ D P + + E P +G+ GE G +GP G
Sbjct: 2121 SNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRG----PP 2176
Query: 174 GPAGDSVE-----AEGRVGDSVDAEGPAG--DSVDAEGPLGDNIQAEGPAGDSVDAEGRV 226
GP G + A G G + +GP+G GP G + GP G +V G
Sbjct: 2177 GPVGGHGDPGPPGAPGLAGPA-GPQGPSGLKGEPGETGPPGRGL--TGPTG-AVGLPGPP 2232
Query: 227 GDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPA 286
G S GP G S G+VG++ + G P DG A GD P + GP
Sbjct: 2233 GPS-GLVGPQG-SPGLPGQVGETGKPGAPGRDG--ASGKDGDRGSPGVPGSPGL--PGPV 2286
Query: 287 GRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAA 346
G GEP +G +P + + + +PG LA D E PG KG +
Sbjct: 2287 G----PKGEPGPTG----APGQAVVGLPGAKGEKGAPGGLAGDLVGE---PGAKG-DRGL 2334
Query: 347 PGDARADAGE-DRVGDGPQQEPGEDEERRERSPEGPREEEAAG 388
PG R + GE R G+ +PGED ++ P+G + + G
Sbjct: 2335 PG-PRGEKGEAGRAGE--PGDPGEDGQKGAPGPKGFKGDPGVG 2374
Score = 79.7 bits (195), Expect = 8e-15
Identities = 128/487 (26%), Positives = 167/487 (34%), Gaps = 79/487 (16%)
Query: 12 PGPQGPPEVPAPLAERPGEPGAAGGEAE-GPEGSEGAEEAPRGAAAVKEAGGGGPDRGP- 69
P P+ P V P ++ GEPG G + GP G G G GP P
Sbjct: 1242 PRPE-PCPVYCPKGQK-GEPGEMGLRGQVGPPGDPGLPG---------RTGAPGPQGPPG 1290
Query: 70 EAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQREP 129
A A+G RG G + G+P A G T GA ++G+ G +G+P R P
Sbjct: 1291 SATAKGERGFPG-ADGRPGSPGRA----GNPGTPGAPGLKGSPGLPGPRGDPGERGPRGP 1345
Query: 130 EDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDS 189
+ Q + P +P GPLGD P +G GD
Sbjct: 1346 KGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDR 1405
Query: 190 VDAEGPAGDSVDAEGP-------LGDNIQAEGPAGDSVDAEGRVGDSVD----------- 231
+ GP G P L + +GP G +G GDS D
Sbjct: 1406 GE-RGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPP-GKKGEKGDSEDGAPGLPGQPGS 1463
Query: 232 -----------AEGPAGDSVDAEGRVGDSVEAGD--PAGDGVEAGVP-AGDSVEAEGPAG 277
A GP GD G +G++ E G+ P G G+P A+GP G
Sbjct: 1464 PGEQGPRGPPGAIGPKGDR-GFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEG 1522
Query: 278 DSMDAEGPAGRARRVSGEPQQSGDGSL------SPQAEAIEVAAGESAGRS--PGELAWD 329
GP GR + GEP + GD ++ P+ E +V G + GE
Sbjct: 1523 ----PPGPTGR-QGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPP 1577
Query: 330 AAEEAEVPGVKGSEEAAPGDARADAGEDRVG----DGPQQEPGEDEERRERSPEGPREEE 385
PG KG PGD R G GP E G+ P GPR +
Sbjct: 1578 GLVLPGDPGPKGD----PGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRD 1633
Query: 386 AAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPR 445
GE+ D P G+ E L GP GE EDG P
Sbjct: 1634 GEVGEK--GDEGPPGDPGLPGKAGERGLRGAPGVRGPV---GEKGDQGDPGEDGRNGSPG 1688
Query: 446 ALGQEHD 452
+ G + D
Sbjct: 1689 SSGPKGD 1695
Score = 76.6 bits (187), Expect = 7e-14
Identities = 130/477 (27%), Positives = 175/477 (36%), Gaps = 83/477 (17%)
Query: 13 GPQGPPEVPAPLAERP--GEPGAAGGEAE----GPEGSEGAEEAPRGAAAVKEAGGGGP- 65
GP G P +P ER G PG G E G G +G +P + + G GP
Sbjct: 1643 GPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPP 1702
Query: 66 -------DRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGA---QQVEGASPGR 115
D GP A +G G G+ EG P+G GA + +EG
Sbjct: 1703 GPPGRLVDTGPGAREKGEPGDRGQ--------EGPRGPKGDPGLPGAPGERGIEGFRGPP 1754
Query: 116 GAQGEP--RGEAQREPE------DSAAPERQEEAEQRPEVPEGSASGEAGD-SVDAEGPL 166
G QG+P RG A + + D + + P P G A+G+AGD D L
Sbjct: 1755 GPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNG-AAGKAGDPGRDGLPGL 1813
Query: 167 GDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRV 226
GP+G G+ G+ G G + + P D +G GDS A GR
Sbjct: 1814 RGEQGLPGPSGPP-GLPGKPGED-GKPGLNGKNGEPGDPGEDG--RKGEKGDS-GASGRE 1868
Query: 227 GDSVDAEGPAGDSVDAEGRVGDSVEAG-----DPAGDGVEAGVPAGDSVEAEGPAGDSMD 281
G +GP G+ A G +G G P G G GVP G + + S
Sbjct: 1869 G----RDGPKGER-GAPGILGPQGPPGLPGPVGPPGQGF-PGVPGGTGPKGDRGETGSKG 1922
Query: 282 AEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVP---- 337
+G G R + GEP GS+ +E A +++ WD + + +P
Sbjct: 1923 EQGLPGE-RGLRGEP-----GSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPER 1976
Query: 338 --GVKG--SEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAAGGEEES 393
G KG E+ PG +GP PGE + +R GP+ E
Sbjct: 1977 RRGPKGDSGEQGPPGK-----------EGPIGFPGERGLKGDRGDPGPQGPPGLALGERG 2025
Query: 394 PDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRALGQE 450
P P G A L G A G GEA R R E GE E G++
Sbjct: 2026 P-PGPSGLAGEPGKPGIPGL------PGRAGGVGEAGRPGERGERGEKGERGEQGRD 2075
Score = 74.7 bits (182), Expect = 3e-13
Identities = 129/500 (25%), Positives = 174/500 (34%), Gaps = 103/500 (20%)
Query: 12 PGPQGPPEVPAPLAER--------------PGEPGAAGGEAEGPEGSEGAEEAP--RGAA 55
PGPQG P V P E+ G+PGAAG GP G+ G P G
Sbjct: 1754 PGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAG--PSGPNGAAGKAGDPGRDGLP 1811
Query: 56 AVK-EAGGGGPDRGPEAEAR----GTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEG 110
++ E G GP P + G G +G+ E G P G + +G + SGA EG
Sbjct: 1812 GLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGK-NGEPGDP-GEDGRKGEKGDSGASGREG 1869
Query: 111 ASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSA----SGEAGDSVDAEGPL 166
+G +G P + P P + P VP G+ GE G + P
Sbjct: 1870 RDGPKGERGAPGILGPQGPPGLPGPV-GPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPG 1928
Query: 167 GDNIEAE-----------GPAGDSVEAEGRVGDSVD------------AEGPAGDSVDAE 203
+ E AG A + ++ D GP GDS + +
Sbjct: 1929 ERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGE-Q 1987
Query: 204 GPLGDNIQAEGPAGDSVDAEGRVGDSVD--AEGPAGDSVDAEGRVGDSVEAGDPAGDGV- 260
GP G EGP G + G GD D +GP G ++ G G S AG+P G+
Sbjct: 1988 GPPG----KEGPIGFPGE-RGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIP 2042
Query: 261 ----------EAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEA 310
EAG P E +GP G + G P G P+
Sbjct: 2043 GLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPG----LPGTP--GPPGPPGPKVSV 2096
Query: 311 IEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGED 370
E G S + P PG+KG+ + PG + D+ G + PG
Sbjct: 2097 DEPGPGLSGEQGP-------------PGLKGA-KGEPG-----SNGDQGPKGDRGVPGIK 2137
Query: 371 EERRERSPEGPREEEAAGGEE--ESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGE 428
+R E P G GE P+ P + RG P + H + GP G
Sbjct: 2138 GDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRG---PPGPVGGH-GDPGPPGAPGL 2193
Query: 429 AARVNGRREDGEASEPRALG 448
A + G EP G
Sbjct: 2194 AGPAGPQGPSGLKGEPGETG 2213
Score = 73.9 bits (180), Expect = 4e-13
Identities = 148/525 (28%), Positives = 174/525 (33%), Gaps = 100/525 (19%)
Query: 12 PGPQGPPEVPAP----------LAERPGEPGAAGGEAEGPEGSEGAE-----EAPRGAAA 56
PGP GP P P L GE GA GG A G GA+ PRG
Sbjct: 2283 PGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKG 2342
Query: 57 VKEAGG--GGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPG 114
G G P + A G +G G+ G P G + G + GA
Sbjct: 2343 EAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGV 2402
Query: 115 RGAQGE--PRGE-AQREPEDS---AAPERQE--EAEQRPEVPEGS-----ASGEAGD--- 158
G G+ PRGE Q P A P +E P P GS ASG GD
Sbjct: 2403 VGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGD 2462
Query: 159 -SVDAEGPLGDNIE-----------AEGPAG-----DSVEAEGRVGD--SVDAEGPAGDS 199
V GP G+ E EGP G S G GD S +G GDS
Sbjct: 2463 PGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDS 2522
Query: 200 VDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAE-GPAGDSVD-----AEGRVGDSVEAG 253
GP GP G D R +D + GP GD+ D ++G GD AG
Sbjct: 2523 AVILGP-------PGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAG 2575
Query: 254 --------DPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAG--RARRVSGEPQQSG--- 300
P G AG+P + +G G R + GE G
Sbjct: 2576 LPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACG 2635
Query: 301 -DGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRV 359
DG + EA GR PG LA E E PGV G A + DR
Sbjct: 2636 LDGEKGDKGEA------GPPGR-PG-LAGHKGEMGE-PGVPGQSGAPGKEGLIGPKGDRG 2686
Query: 360 GDGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAE 419
DG G+ E+ ER G G + S P S G PE L E
Sbjct: 2687 FDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSA-GPPGPPGSVGPRGPEG-LQGQKGE 2744
Query: 420 EGPAEGSGEAARVNGRREDGEASEPRALGQEHDITLFVKAGYDGE 464
GP G R G P A G+ + AG GE
Sbjct: 2745 RGPP----------GERVVGAPGVPGAPGERGEQGRPGPAGPRGE 2779
>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
sapiens]
Length = 1650
Score = 89.4 bits (220), Expect = 1e-17
Identities = 146/504 (28%), Positives = 189/504 (37%), Gaps = 104/504 (20%)
Query: 12 PGPQGPPEVPAP-----------LAERPGEPGAAGGEAE-GPEGSEGAEEAPRGAAA--- 56
PGPQGP P P L PG+ G G + + GP G G P+GAA
Sbjct: 793 PGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV-VGPQGAAGETG 851
Query: 57 -VKEAGGGGPDRGP-EAEARGTRGAHGETEAEEGAP--EGAEVPQGGEETSGAQQVEGAS 112
+ E G GP P E GT G G T+ + G P G + P G G + + G +
Sbjct: 852 PMGERGHPGPPGPPGEQGLPGTAGKEG-TKGDPGPPGAPGKDGPAGLRGFPGERGLPGTA 910
Query: 113 PGRGAQGE-----PRGEAQREPEDSAAPERQEEAEQRPEVPEG--SASGEAGDSVDAEGP 165
G G +G P G A E AA P+G A+GE G + +GP
Sbjct: 911 GGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGE-KGP 969
Query: 166 LG----DNIEA----EGPAGDSVEA-----EGRVGD--------SVDAEGPAGDSVDAEG 204
+G D ++ GPAG A +G VGD + GP G G
Sbjct: 970 IGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPG----PPG 1025
Query: 205 PLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGV 264
P+G + G AG A+G G A GP G A+G G G P G++ G+
Sbjct: 1026 PIGP-VGQPGAAG----ADGEPG----ARGPQG-HFGAKGDEGTRGFNGPPGPIGLQ-GL 1074
Query: 265 PAGDSVEAE----GPAG--DSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGES 318
P + E GP G GPAG + G G+L P E E GES
Sbjct: 1075 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE--PGES 1132
Query: 319 AGRSPGELAWDAAEEAEVPGVKG--------SEEAAPGDARADAGEDRVG-DGPQQEPGE 369
SPG PGVKG E PG+ + G DGP+ PG
Sbjct: 1133 G--SPGIQG--------EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGP 1182
Query: 370 DEERRERSPE---GPREEEAAGGE--EESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAE 424
+ P GPR ++ A G+ E+ P G P L + GPA
Sbjct: 1183 VGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP----LGKRGPAG 1238
Query: 425 GSGEAARVNGRREDGEASEPRALG 448
G R G+ G +P A+G
Sbjct: 1239 SPGSEGRQGGK---GAKGDPGAIG 1259
Score = 88.2 bits (217), Expect = 2e-17
Identities = 127/430 (29%), Positives = 168/430 (39%), Gaps = 61/430 (14%)
Query: 13 GPQGPPEVPAPLAERPGEPGAAGGEAE----GPEGSEGA--EEAPRGAAAVKEAGGGGPD 66
G GPP P P+ G+PGAAG + E GP+G GA +E RG G P
Sbjct: 1016 GEHGPPGPPGPIGP-VGQPGAAGADGEPGARGPQGHFGAKGDEGTRGF-------NGPPG 1067
Query: 67 RGPEAEARGTRGAHGET-EAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEA 125
G G GET + P G P+G +GA +G G G G P GE
Sbjct: 1068 PIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP-GE- 1125
Query: 126 QREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDA-----EGPLGDNIEAEGPAGDSV 180
+ EP +S +P Q E + E GE+G + +GP GD +GP G+
Sbjct: 1126 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGD----DGPKGNP- 1180
Query: 181 EAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSV 240
G VG D GP G+ GP G + A+G G+ +G G + GP G++
Sbjct: 1181 ---GPVGFPGDP-GPPGEG----GPRGQD-GAKGDRGE----DGEPGQP-GSPGPTGEN- 1225
Query: 241 DAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSG 300
G +G AG P +G + G A A G G + GPAG A + + +
Sbjct: 1226 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPV-GPAGPAGKPGPDGLRGL 1284
Query: 301 DGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVG 360
GS+ Q A AG PG + PG+ G GDA A + G
Sbjct: 1285 PGSVGQQGRP---GATGQAG-PPGPVG--------PPGLPGLR----GDAGAKGEKGHPG 1328
Query: 361 -DGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSS-PHGEASRGAAEPEAQLSNHLA 418
G PGE E+ +R GP+ GE P +S P G A
Sbjct: 1329 LIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKG 1388
Query: 419 EEGPAEGSGE 428
GP GE
Sbjct: 1389 ATGPGGPKGE 1398
Score = 68.6 bits (166), Expect = 2e-11
Identities = 102/334 (30%), Positives = 134/334 (40%), Gaps = 66/334 (19%)
Query: 3 EAAEP-EGVAPGPQGPPEVPAPLAER--------PGEPGAAGGEAEGPEGSEGAEEAPRG 53
E EP E +PG QG P V P ER PGEPG G +GP G +G + P
Sbjct: 1125 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG--PKGPTGDDGPKGNPGP 1182
Query: 54 AAAVKEAG--GGGPDRGPEAEARGTRGAHGETEAEEGAP-----EGAEVPQGGEETSGAQ 106
+ G G G RG + A+G RG GE + G+P G P G +G+
Sbjct: 1183 VGFPGDPGPPGEGGPRGQDG-AKGDRGEDGE-PGQPGSPGPTGENGPPGPLGKRGPAGSP 1240
Query: 107 QVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPL 166
EG G+GA+G+P AP + P P G A D + L
Sbjct: 1241 GSEGRQGGKGAKGDPGA--------IGAP-----GKTGPVGPAGPAGKPGPDGLRG---L 1284
Query: 167 GDNIEAEGPAGDSVEA--EGRVGDSVDAEGPAGDSVDAEGPLGDN--IQAEGPAGDSVDA 222
++ +G G + +A G VG G GD+ A+G G I GP G+
Sbjct: 1285 PGSVGQQGRPGATGQAGPPGPVGPP-GLPGLRGDA-GAKGEKGHPGLIGLIGPPGE---- 1338
Query: 223 EGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAG--DSM 280
+G GD GP G S +G +G +G P G G G+P GPAG +
Sbjct: 1339 QGEKGDR-GLPGPQG-SPGQKGEMGIPGASG-PIGPGGPPGLP--------GPAGPKGAK 1387
Query: 281 DAEGPAG--RARRVSGEPQQSGDGSLSPQAEAIE 312
A GP G + V G P G P E I+
Sbjct: 1388 GATGPGGPKGEKGVQGPPGHPG-----PPGEVIQ 1416
Score = 63.5 bits (153), Expect = 6e-10
Identities = 122/482 (25%), Positives = 162/482 (33%), Gaps = 80/482 (16%)
Query: 13 GPQGPPEVPAPLAERPGEPGAAGGEAE-GPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEA 71
G G +P P PGE G G + E GP G G E PRG K G P
Sbjct: 488 GDTGAQGLPGP----PGEDGERGDDGEIGPRGLPG-ESGPRGLLGPK----GPPGIPGPP 538
Query: 72 EARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQREPED 131
RG G G P+G+ PQG E PG+ QG P + P+
Sbjct: 539 GVRGMDGPQG--------PKGSLGPQG----------EPGPPGQ--QGTPGTQGLPGPQG 578
Query: 132 SAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLG--DNIEAEGPAG------------ 177
+ P ++ + +P +P S EGP G N GP G
Sbjct: 579 AIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKG 638
Query: 178 -DSVEA-EGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDA----EGRVGDSVD 231
D + +G G+ + +G G D G GD + P D +GR G + D
Sbjct: 639 VDGIRGLKGHKGEKGE-DGFPGFKGDI-GVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 696
Query: 232 AEGPAGDSVDAEGRVGDSVEAGDPAGDGVEA--GVPAGDSVEAEGPAGDSMDAEGPAGRA 289
GP G + +G++G G P G + G P E A GP G
Sbjct: 697 -PGPPG-LMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGE- 753
Query: 290 RRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAE-VPGVKG-----SE 343
R +G Q G + ++ A + G+ PGE + PG KG +
Sbjct: 754 RGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK 813
Query: 344 EAAPG--DARADAG-EDRVGD-------GPQQEPGED---EERRERSPEGPREEE----A 386
+ PG R + G + + G GPQ GE ER P GP E+
Sbjct: 814 DGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGT 873
Query: 387 AGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRA 446
AG E D P G + G A G G G A P
Sbjct: 874 AGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGE 933
Query: 447 LG 448
G
Sbjct: 934 RG 935
Score = 58.2 bits (139), Expect = 3e-08
Identities = 129/495 (26%), Positives = 168/495 (33%), Gaps = 86/495 (17%)
Query: 15 QGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEAR 74
+GPP P RPG G G E + + PRG + G RG A A
Sbjct: 400 RGPPG-PMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRG-RAGAD 457
Query: 75 GTRGAHGETEAE-----EGAPEGAEVPQGGEETSGAQQVEGASPG----RGAQGE--PRG 123
G RG G+ + +G P G +G +GAQ + G PG RG GE PRG
Sbjct: 458 GARGMPGDPGVKGDRGFDGLP-GLPGEKGHRGDTGAQGLPG-PPGEDGERGDDGEIGPRG 515
Query: 124 -EAQREPEDSAAPERQE--------EAEQRPEVPEGS--ASGEAG--------DSVDAEG 164
+ P P+ P+ P+GS GE G + G
Sbjct: 516 LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG 575
Query: 165 PLGDNIEAEGPAGDSVEAEGRVG--DSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDA 222
P G A GP G+ +G+ G ++GP G EGP G +GP+G
Sbjct: 576 PQG----AIGPHGEK-GPQGKPGLPGMPGSDGPPGHP-GKEGPPGTK-GNQGPSG----P 624
Query: 223 EGRVGDSVDAEGPAG-DSVDA----EGRVGDSVEAGDPA--------GDGVEAGVPAGDS 269
+G +G GP G VD +G G+ E G P GD E GVP
Sbjct: 625 QGPLG----YPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRG 680
Query: 270 VEA-------EGPAGDS-----MDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGE 317
+ GP GD M +G G +Q GSL A+GE
Sbjct: 681 EDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLG--FPGFPGASGE 738
Query: 318 SAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERS 377
R + E G +G ++ A GDGP PG ER
Sbjct: 739 KGARGLSGKSGPRGERGPT-GPRGQRGPRGATGKSGAKGTSGGDGPHGPPG---ERGLPG 794
Query: 378 PEGPREEEAAGGEEESP--DSSPHGEASRGAAEPEAQLS--NHLAEEGPAEGSGEAARVN 433
P+GP G P D P RG + + GP +GE +
Sbjct: 795 PQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMG 854
Query: 434 GRREDGEASEPRALG 448
R G P G
Sbjct: 855 ERGHPGPPGPPGEQG 869
>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
sapiens]
Length = 1629
Score = 89.4 bits (220), Expect = 1e-17
Identities = 146/504 (28%), Positives = 189/504 (37%), Gaps = 104/504 (20%)
Query: 12 PGPQGPPEVPAP-----------LAERPGEPGAAGGEAE-GPEGSEGAEEAPRGAAA--- 56
PGPQGP P P L PG+ G G + + GP G G P+GAA
Sbjct: 772 PGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV-VGPQGAAGETG 830
Query: 57 -VKEAGGGGPDRGP-EAEARGTRGAHGETEAEEGAP--EGAEVPQGGEETSGAQQVEGAS 112
+ E G GP P E GT G G T+ + G P G + P G G + + G +
Sbjct: 831 PMGERGHPGPPGPPGEQGLPGTAGKEG-TKGDPGPPGAPGKDGPAGLRGFPGERGLPGTA 889
Query: 113 PGRGAQGE-----PRGEAQREPEDSAAPERQEEAEQRPEVPEG--SASGEAGDSVDAEGP 165
G G +G P G A E AA P+G A+GE G + +GP
Sbjct: 890 GGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGE-KGP 948
Query: 166 LG----DNIEA----EGPAGDSVEA-----EGRVGD--------SVDAEGPAGDSVDAEG 204
+G D ++ GPAG A +G VGD + GP G G
Sbjct: 949 IGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPG----PPG 1004
Query: 205 PLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGV 264
P+G + G AG A+G G A GP G A+G G G P G++ G+
Sbjct: 1005 PIGP-VGQPGAAG----ADGEPG----ARGPQG-HFGAKGDEGTRGFNGPPGPIGLQ-GL 1053
Query: 265 PAGDSVEAE----GPAG--DSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGES 318
P + E GP G GPAG + G G+L P E E GES
Sbjct: 1054 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE--PGES 1111
Query: 319 AGRSPGELAWDAAEEAEVPGVKG--------SEEAAPGDARADAGEDRVG-DGPQQEPGE 369
SPG PGVKG E PG+ + G DGP+ PG
Sbjct: 1112 G--SPGIQG--------EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGP 1161
Query: 370 DEERRERSPE---GPREEEAAGGE--EESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAE 424
+ P GPR ++ A G+ E+ P G P L + GPA
Sbjct: 1162 VGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP----LGKRGPAG 1217
Query: 425 GSGEAARVNGRREDGEASEPRALG 448
G R G+ G +P A+G
Sbjct: 1218 SPGSEGRQGGK---GAKGDPGAIG 1238
Score = 88.2 bits (217), Expect = 2e-17
Identities = 127/430 (29%), Positives = 168/430 (39%), Gaps = 61/430 (14%)
Query: 13 GPQGPPEVPAPLAERPGEPGAAGGEAE----GPEGSEGA--EEAPRGAAAVKEAGGGGPD 66
G GPP P P+ G+PGAAG + E GP+G GA +E RG G P
Sbjct: 995 GEHGPPGPPGPIGP-VGQPGAAGADGEPGARGPQGHFGAKGDEGTRGF-------NGPPG 1046
Query: 67 RGPEAEARGTRGAHGET-EAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEA 125
G G GET + P G P+G +GA +G G G G P GE
Sbjct: 1047 PIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP-GE- 1104
Query: 126 QREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDA-----EGPLGDNIEAEGPAGDSV 180
+ EP +S +P Q E + E GE+G + +GP GD +GP G+
Sbjct: 1105 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGD----DGPKGNP- 1159
Query: 181 EAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSV 240
G VG D GP G+ GP G + A+G G+ +G G + GP G++
Sbjct: 1160 ---GPVGFPGDP-GPPGEG----GPRGQD-GAKGDRGE----DGEPGQP-GSPGPTGEN- 1204
Query: 241 DAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSG 300
G +G AG P +G + G A A G G + GPAG A + + +
Sbjct: 1205 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPV-GPAGPAGKPGPDGLRGL 1263
Query: 301 DGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVG 360
GS+ Q A AG PG + PG+ G GDA A + G
Sbjct: 1264 PGSVGQQGRP---GATGQAG-PPGPVG--------PPGLPGLR----GDAGAKGEKGHPG 1307
Query: 361 -DGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSS-PHGEASRGAAEPEAQLSNHLA 418
G PGE E+ +R GP+ GE P +S P G A
Sbjct: 1308 LIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKG 1367
Query: 419 EEGPAEGSGE 428
GP GE
Sbjct: 1368 ATGPGGPKGE 1377
Score = 68.6 bits (166), Expect = 2e-11
Identities = 102/334 (30%), Positives = 134/334 (40%), Gaps = 66/334 (19%)
Query: 3 EAAEP-EGVAPGPQGPPEVPAPLAER--------PGEPGAAGGEAEGPEGSEGAEEAPRG 53
E EP E +PG QG P V P ER PGEPG G +GP G +G + P
Sbjct: 1104 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG--PKGPTGDDGPKGNPGP 1161
Query: 54 AAAVKEAG--GGGPDRGPEAEARGTRGAHGETEAEEGAP-----EGAEVPQGGEETSGAQ 106
+ G G G RG + A+G RG GE + G+P G P G +G+
Sbjct: 1162 VGFPGDPGPPGEGGPRGQDG-AKGDRGEDGE-PGQPGSPGPTGENGPPGPLGKRGPAGSP 1219
Query: 107 QVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPL 166
EG G+GA+G+P AP + P P G A D + L
Sbjct: 1220 GSEGRQGGKGAKGDPGA--------IGAP-----GKTGPVGPAGPAGKPGPDGLRG---L 1263
Query: 167 GDNIEAEGPAGDSVEA--EGRVGDSVDAEGPAGDSVDAEGPLGDN--IQAEGPAGDSVDA 222
++ +G G + +A G VG G GD+ A+G G I GP G+
Sbjct: 1264 PGSVGQQGRPGATGQAGPPGPVGPP-GLPGLRGDA-GAKGEKGHPGLIGLIGPPGE---- 1317
Query: 223 EGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAG--DSM 280
+G GD GP G S +G +G +G P G G G+P GPAG +
Sbjct: 1318 QGEKGDR-GLPGPQG-SPGQKGEMGIPGASG-PIGPGGPPGLP--------GPAGPKGAK 1366
Query: 281 DAEGPAG--RARRVSGEPQQSGDGSLSPQAEAIE 312
A GP G + V G P G P E I+
Sbjct: 1367 GATGPGGPKGEKGVQGPPGHPG-----PPGEVIQ 1395
Score = 63.5 bits (153), Expect = 6e-10
Identities = 122/482 (25%), Positives = 162/482 (33%), Gaps = 80/482 (16%)
Query: 13 GPQGPPEVPAPLAERPGEPGAAGGEAE-GPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEA 71
G G +P P PGE G G + E GP G G E PRG K G P
Sbjct: 467 GDTGAQGLPGP----PGEDGERGDDGEIGPRGLPG-ESGPRGLLGPK----GPPGIPGPP 517
Query: 72 EARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQREPED 131
RG G G P+G+ PQG E PG+ QG P + P+
Sbjct: 518 GVRGMDGPQG--------PKGSLGPQG----------EPGPPGQ--QGTPGTQGLPGPQG 557
Query: 132 SAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLG--DNIEAEGPAG------------ 177
+ P ++ + +P +P S EGP G N GP G
Sbjct: 558 AIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKG 617
Query: 178 -DSVEA-EGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDA----EGRVGDSVD 231
D + +G G+ + +G G D G GD + P D +GR G + D
Sbjct: 618 VDGIRGLKGHKGEKGE-DGFPGFKGDI-GVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 675
Query: 232 AEGPAGDSVDAEGRVGDSVEAGDPAGDGVEA--GVPAGDSVEAEGPAGDSMDAEGPAGRA 289
GP G + +G++G G P G + G P E A GP G
Sbjct: 676 -PGPPG-LMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGE- 732
Query: 290 RRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAE-VPGVKG-----SE 343
R +G Q G + ++ A + G+ PGE + PG KG +
Sbjct: 733 RGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK 792
Query: 344 EAAPG--DARADAG-EDRVGD-------GPQQEPGED---EERRERSPEGPREEE----A 386
+ PG R + G + + G GPQ GE ER P GP E+
Sbjct: 793 DGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGT 852
Query: 387 AGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRA 446
AG E D P G + G A G G G A P
Sbjct: 853 AGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGE 912
Query: 447 LG 448
G
Sbjct: 913 RG 914
Score = 58.2 bits (139), Expect = 3e-08
Identities = 129/495 (26%), Positives = 168/495 (33%), Gaps = 86/495 (17%)
Query: 15 QGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEAR 74
+GPP P RPG G G E + + PRG + G RG A A
Sbjct: 379 RGPPG-PMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRG-RAGAD 436
Query: 75 GTRGAHGETEAE-----EGAPEGAEVPQGGEETSGAQQVEGASPG----RGAQGE--PRG 123
G RG G+ + +G P G +G +GAQ + G PG RG GE PRG
Sbjct: 437 GARGMPGDPGVKGDRGFDGLP-GLPGEKGHRGDTGAQGLPG-PPGEDGERGDDGEIGPRG 494
Query: 124 -EAQREPEDSAAPERQE--------EAEQRPEVPEGS--ASGEAG--------DSVDAEG 164
+ P P+ P+ P+GS GE G + G
Sbjct: 495 LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG 554
Query: 165 PLGDNIEAEGPAGDSVEAEGRVG--DSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDA 222
P G A GP G+ +G+ G ++GP G EGP G +GP+G
Sbjct: 555 PQG----AIGPHGEK-GPQGKPGLPGMPGSDGPPGHP-GKEGPPGTK-GNQGPSG----P 603
Query: 223 EGRVGDSVDAEGPAG-DSVDA----EGRVGDSVEAGDPA--------GDGVEAGVPAGDS 269
+G +G GP G VD +G G+ E G P GD E GVP
Sbjct: 604 QGPLG----YPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRG 659
Query: 270 VEA-------EGPAGDS-----MDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGE 317
+ GP GD M +G G +Q GSL A+GE
Sbjct: 660 EDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLG--FPGFPGASGE 717
Query: 318 SAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERS 377
R + E G +G ++ A GDGP PG ER
Sbjct: 718 KGARGLSGKSGPRGERGPT-GPRGQRGPRGATGKSGAKGTSGGDGPHGPPG---ERGLPG 773
Query: 378 PEGPREEEAAGGEEESP--DSSPHGEASRGAAEPEAQLS--NHLAEEGPAEGSGEAARVN 433
P+GP G P D P RG + + GP +GE +
Sbjct: 774 PQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMG 833
Query: 434 GRREDGEASEPRALG 448
R G P G
Sbjct: 834 ERGHPGPPGPPGEQG 848
>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
sapiens]
Length = 1736
Score = 89.4 bits (220), Expect = 1e-17
Identities = 146/504 (28%), Positives = 189/504 (37%), Gaps = 104/504 (20%)
Query: 12 PGPQGPPEVPAP-----------LAERPGEPGAAGGEAE-GPEGSEGAEEAPRGAAA--- 56
PGPQGP P P L PG+ G G + + GP G G P+GAA
Sbjct: 879 PGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV-VGPQGAAGETG 937
Query: 57 -VKEAGGGGPDRGP-EAEARGTRGAHGETEAEEGAP--EGAEVPQGGEETSGAQQVEGAS 112
+ E G GP P E GT G G T+ + G P G + P G G + + G +
Sbjct: 938 PMGERGHPGPPGPPGEQGLPGTAGKEG-TKGDPGPPGAPGKDGPAGLRGFPGERGLPGTA 996
Query: 113 PGRGAQGE-----PRGEAQREPEDSAAPERQEEAEQRPEVPEG--SASGEAGDSVDAEGP 165
G G +G P G A E AA P+G A+GE G + +GP
Sbjct: 997 GGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGE-KGP 1055
Query: 166 LG----DNIEA----EGPAGDSVEA-----EGRVGD--------SVDAEGPAGDSVDAEG 204
+G D ++ GPAG A +G VGD + GP G G
Sbjct: 1056 IGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPG----PPG 1111
Query: 205 PLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGV 264
P+G + G AG A+G G A GP G A+G G G P G++ G+
Sbjct: 1112 PIGP-VGQPGAAG----ADGEPG----ARGPQG-HFGAKGDEGTRGFNGPPGPIGLQ-GL 1160
Query: 265 PAGDSVEAE----GPAG--DSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGES 318
P + E GP G GPAG + G G+L P E E GES
Sbjct: 1161 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE--PGES 1218
Query: 319 AGRSPGELAWDAAEEAEVPGVKG--------SEEAAPGDARADAGEDRVG-DGPQQEPGE 369
SPG PGVKG E PG+ + G DGP+ PG
Sbjct: 1219 G--SPGIQG--------EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGP 1268
Query: 370 DEERRERSPE---GPREEEAAGGE--EESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAE 424
+ P GPR ++ A G+ E+ P G P L + GPA
Sbjct: 1269 VGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP----LGKRGPAG 1324
Query: 425 GSGEAARVNGRREDGEASEPRALG 448
G R G+ G +P A+G
Sbjct: 1325 SPGSEGRQGGK---GAKGDPGAIG 1345
Score = 88.2 bits (217), Expect = 2e-17
Identities = 127/430 (29%), Positives = 168/430 (39%), Gaps = 61/430 (14%)
Query: 13 GPQGPPEVPAPLAERPGEPGAAGGEAE----GPEGSEGA--EEAPRGAAAVKEAGGGGPD 66
G GPP P P+ G+PGAAG + E GP+G GA +E RG G P
Sbjct: 1102 GEHGPPGPPGPIGP-VGQPGAAGADGEPGARGPQGHFGAKGDEGTRGF-------NGPPG 1153
Query: 67 RGPEAEARGTRGAHGET-EAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEA 125
G G GET + P G P+G +GA +G G G G P GE
Sbjct: 1154 PIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP-GE- 1211
Query: 126 QREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDA-----EGPLGDNIEAEGPAGDSV 180
+ EP +S +P Q E + E GE+G + +GP GD +GP G+
Sbjct: 1212 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGD----DGPKGNP- 1266
Query: 181 EAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSV 240
G VG D GP G+ GP G + A+G G+ +G G + GP G++
Sbjct: 1267 ---GPVGFPGDP-GPPGEG----GPRGQD-GAKGDRGE----DGEPGQP-GSPGPTGEN- 1311
Query: 241 DAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSG 300
G +G AG P +G + G A A G G + GPAG A + + +
Sbjct: 1312 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPV-GPAGPAGKPGPDGLRGL 1370
Query: 301 DGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVG 360
GS+ Q A AG PG + PG+ G GDA A + G
Sbjct: 1371 PGSVGQQGRP---GATGQAG-PPGPVG--------PPGLPGLR----GDAGAKGEKGHPG 1414
Query: 361 -DGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSS-PHGEASRGAAEPEAQLSNHLA 418
G PGE E+ +R GP+ GE P +S P G A
Sbjct: 1415 LIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKG 1474
Query: 419 EEGPAEGSGE 428
GP GE
Sbjct: 1475 ATGPGGPKGE 1484
Score = 68.6 bits (166), Expect = 2e-11
Identities = 102/334 (30%), Positives = 134/334 (40%), Gaps = 66/334 (19%)
Query: 3 EAAEP-EGVAPGPQGPPEVPAPLAER--------PGEPGAAGGEAEGPEGSEGAEEAPRG 53
E EP E +PG QG P V P ER PGEPG G +GP G +G + P
Sbjct: 1211 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG--PKGPTGDDGPKGNPGP 1268
Query: 54 AAAVKEAG--GGGPDRGPEAEARGTRGAHGETEAEEGAP-----EGAEVPQGGEETSGAQ 106
+ G G G RG + A+G RG GE + G+P G P G +G+
Sbjct: 1269 VGFPGDPGPPGEGGPRGQDG-AKGDRGEDGE-PGQPGSPGPTGENGPPGPLGKRGPAGSP 1326
Query: 107 QVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPL 166
EG G+GA+G+P AP + P P G A D + L
Sbjct: 1327 GSEGRQGGKGAKGDPGA--------IGAP-----GKTGPVGPAGPAGKPGPDGLRG---L 1370
Query: 167 GDNIEAEGPAGDSVEA--EGRVGDSVDAEGPAGDSVDAEGPLGDN--IQAEGPAGDSVDA 222
++ +G G + +A G VG G GD+ A+G G I GP G+
Sbjct: 1371 PGSVGQQGRPGATGQAGPPGPVGPP-GLPGLRGDA-GAKGEKGHPGLIGLIGPPGE---- 1424
Query: 223 EGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAG--DSM 280
+G GD GP G S +G +G +G P G G G+P GPAG +
Sbjct: 1425 QGEKGDR-GLPGPQG-SPGQKGEMGIPGASG-PIGPGGPPGLP--------GPAGPKGAK 1473
Query: 281 DAEGPAG--RARRVSGEPQQSGDGSLSPQAEAIE 312
A GP G + V G P G P E I+
Sbjct: 1474 GATGPGGPKGEKGVQGPPGHPG-----PPGEVIQ 1502
Score = 63.5 bits (153), Expect = 6e-10
Identities = 122/482 (25%), Positives = 162/482 (33%), Gaps = 80/482 (16%)
Query: 13 GPQGPPEVPAPLAERPGEPGAAGGEAE-GPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEA 71
G G +P P PGE G G + E GP G G E PRG K G P
Sbjct: 574 GDTGAQGLPGP----PGEDGERGDDGEIGPRGLPG-ESGPRGLLGPK----GPPGIPGPP 624
Query: 72 EARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQREPED 131
RG G G P+G+ PQG E PG+ QG P + P+
Sbjct: 625 GVRGMDGPQG--------PKGSLGPQG----------EPGPPGQ--QGTPGTQGLPGPQG 664
Query: 132 SAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLG--DNIEAEGPAG------------ 177
+ P ++ + +P +P S EGP G N GP G
Sbjct: 665 AIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKG 724
Query: 178 -DSVEA-EGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDA----EGRVGDSVD 231
D + +G G+ + +G G D G GD + P D +GR G + D
Sbjct: 725 VDGIRGLKGHKGEKGE-DGFPGFKGDI-GVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 782
Query: 232 AEGPAGDSVDAEGRVGDSVEAGDPAGDGVEA--GVPAGDSVEAEGPAGDSMDAEGPAGRA 289
GP G + +G++G G P G + G P E A GP G
Sbjct: 783 -PGPPG-LMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGE- 839
Query: 290 RRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAE-VPGVKG-----SE 343
R +G Q G + ++ A + G+ PGE + PG KG +
Sbjct: 840 RGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK 899
Query: 344 EAAPG--DARADAG-EDRVGD-------GPQQEPGED---EERRERSPEGPREEE----A 386
+ PG R + G + + G GPQ GE ER P GP E+
Sbjct: 900 DGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGT 959
Query: 387 AGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRA 446
AG E D P G + G A G G G A P
Sbjct: 960 AGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGE 1019
Query: 447 LG 448
G
Sbjct: 1020 RG 1021
Score = 58.2 bits (139), Expect = 3e-08
Identities = 129/495 (26%), Positives = 168/495 (33%), Gaps = 86/495 (17%)
Query: 15 QGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEAR 74
+GPP P RPG G G E + + PRG + G RG A A
Sbjct: 486 RGPPG-PMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRG-RAGAD 543
Query: 75 GTRGAHGETEAE-----EGAPEGAEVPQGGEETSGAQQVEGASPG----RGAQGE--PRG 123
G RG G+ + +G P G +G +GAQ + G PG RG GE PRG
Sbjct: 544 GARGMPGDPGVKGDRGFDGLP-GLPGEKGHRGDTGAQGLPG-PPGEDGERGDDGEIGPRG 601
Query: 124 -EAQREPEDSAAPERQE--------EAEQRPEVPEGS--ASGEAG--------DSVDAEG 164
+ P P+ P+ P+GS GE G + G
Sbjct: 602 LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG 661
Query: 165 PLGDNIEAEGPAGDSVEAEGRVG--DSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDA 222
P G A GP G+ +G+ G ++GP G EGP G +GP+G
Sbjct: 662 PQG----AIGPHGEK-GPQGKPGLPGMPGSDGPPGHP-GKEGPPGTK-GNQGPSG----P 710
Query: 223 EGRVGDSVDAEGPAG-DSVDA----EGRVGDSVEAGDPA--------GDGVEAGVPAGDS 269
+G +G GP G VD +G G+ E G P GD E GVP
Sbjct: 711 QGPLG----YPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRG 766
Query: 270 VEA-------EGPAGDS-----MDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGE 317
+ GP GD M +G G +Q GSL A+GE
Sbjct: 767 EDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLG--FPGFPGASGE 824
Query: 318 SAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERS 377
R + E G +G ++ A GDGP PG ER
Sbjct: 825 KGARGLSGKSGPRGERGPT-GPRGQRGPRGATGKSGAKGTSGGDGPHGPPG---ERGLPG 880
Query: 378 PEGPREEEAAGGEEESP--DSSPHGEASRGAAEPEAQLS--NHLAEEGPAEGSGEAARVN 433
P+GP G P D P RG + + GP +GE +
Sbjct: 881 PQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMG 940
Query: 434 GRREDGEASEPRALG 448
R G P G
Sbjct: 941 ERGHPGPPGPPGEQG 955
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 89.0 bits (219), Expect = 1e-17
Identities = 144/489 (29%), Positives = 181/489 (37%), Gaps = 71/489 (14%)
Query: 2 AEAAEPEGVAPGPQGPPEVP-AP-LAERPGEPGAAGGE-AEGPEGSEGAEEAPRGAAAVK 58
A + + APG +GPP + AP L G PG GG+ A GP G GA P
Sbjct: 670 APGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPG 729
Query: 59 EAGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSG--AQQVEGASPG-- 114
E GG G GP+ + G + + P G P G +G + EG +PG
Sbjct: 730 ERGGLG-SPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLP 788
Query: 115 --RGAQGEPRGEAQREPEDSA----APERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGD 168
G +G P + P A AP + E + E GE G GP G
Sbjct: 789 GIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPP-GVAGPPGG 847
Query: 169 NIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGD 228
+ A P V+ E A G G + GP G N GP G S + G+ G
Sbjct: 848 SGPAGPPGPQGVKGERGSPGGPGAAGFPG-ARGLPGPPGSN-GNPGPPGPS-GSPGKDG- 903
Query: 229 SVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAG- 287
GPAG++ A G G S GD AG E G P A+GP G A GP G
Sbjct: 904 ---PPGPAGNT-GAPGSPGVSGPKGD-AGQPGEKGSPG-----AQGPPG----APGPLGI 949
Query: 288 ----RARRVSGEPQQSGD-GSLSPQAEAIEVA-------AGESAGRSPGELAWDAAEEAE 335
AR ++G P G GS PQ E +GE P L A E
Sbjct: 950 AGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGE 1009
Query: 336 VPGVKGS--EEAAPGDARADAGE-DRVGDGPQQEPGEDEERRERSPEGPREEEAAGGEE- 391
PG G+ + PG + G+ DR +G PG P GP + GE
Sbjct: 1010 -PGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESG 1068
Query: 392 -ESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGE-----AARVNGRR----EDGEA 441
P +P SRGA P +GP GE AA + G R G
Sbjct: 1069 PAGPAGAPGPAGSRGAPGP----------QGPRGDKGETGERGAAGIKGHRGFPGNPGAP 1118
Query: 442 SEPRALGQE 450
P GQ+
Sbjct: 1119 GSPGPAGQQ 1127
Score = 86.3 bits (212), Expect = 9e-17
Identities = 137/469 (29%), Positives = 172/469 (36%), Gaps = 94/469 (20%)
Query: 12 PGPQGPPEVPAP--LAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGP 69
PGP GPP P P + PG PG+ G +GP G G +AG GP P
Sbjct: 173 PGPAGPPGPPGPPGTSGHPGSPGSPG--YQGPPGEPG------------QAGPSGPPGPP 218
Query: 70 EA-EARGTRGAHGETEAEEGAP--EGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQ 126
A G G GE+ G P G P G + +G G RG G
Sbjct: 219 GAIGPSGPAGKDGES-GRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGR-----N 272
Query: 127 REPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAG-----DSVE 181
E ++ AP + E GE G A GP+G A G G +
Sbjct: 273 GEKGETGAPGLK---------GENGLPGENG----APGPMGPR-GAPGERGRPGLPGAAG 318
Query: 182 AEGRVG--DSVDAEGPAGDSVDAEGPLGDNIQAE-GPAGD--SVDAEGRVGDSVDAEGPA 236
A G G S GP G A P + E GPAG S A G+ G+ GP
Sbjct: 319 ARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGE----PGPQ 374
Query: 237 GDSVDAEGRVGDSVEAGDPAGDGV--EAGVP-AGDSVEAEGPAGDSMDAEGPAGRARRVS 293
G + A+G G G P G G AG+P A + A GP G + A G G R +
Sbjct: 375 GHA-GAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPA-GANGAPG-LRGGA 431
Query: 294 GEPQQSG-DGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSE--EAAPGDA 350
GEP ++G G P+ E E PG VPG KG + + +PG+
Sbjct: 432 GEPGKNGAKGEPGPRGERGEAGI-------PG-----------VPGAKGEDGKDGSPGEP 473
Query: 351 RADAGEDRVGD----------GPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHG 400
A+ G+ GP PGE ER GP A G E D P G
Sbjct: 474 GANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAG-EPGRDGVPGG 532
Query: 401 EASRG-AAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRALG 448
RG P S+ + GP GE+ R G +P +G
Sbjct: 533 PGMRGMPGSPGGPGSD--GKPGPPGSQGESGRPGPPGPSGPRGQPGVMG 579
Score = 83.2 bits (204), Expect = 7e-16
Identities = 122/445 (27%), Positives = 161/445 (36%), Gaps = 71/445 (15%)
Query: 7 PEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAE-GPEGSEGAEEAPRGAAAVKEAG-GGG 64
P G APG +G P +P R G GA G + + GP G G P A E G G
Sbjct: 301 PRG-APGERGRPGLPGAAGAR-GNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGS 358
Query: 65 PDRGPEAEARGTRGAHGETEAE-EGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRG 123
P RG G G A+ P G GG+ G + GA GA+G P G
Sbjct: 359 PGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPP-G 417
Query: 124 EAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAE 183
A A P + G+ + GP G+ EA P + E
Sbjct: 418 PA--------------GANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGE 463
Query: 184 -GRVGDSVD--AEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSV 240
G+ G + A G G + + P GPAG + G G+ +GPAG+
Sbjct: 464 DGKDGSPGEPGANGLPGAAGERGAP-----GFRGPAGPN----GIPGE----KGPAGER- 509
Query: 241 DAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAE-GPAGRARRVSGEPQQS 299
A G G AG+P DGV G G P G D + GP G ++ SG P
Sbjct: 510 GAPGPAGPRGAAGEPGRDGVPGG--PGMRGMPGSPGGPGSDGKPGPPG-SQGESGRPGPP 566
Query: 300 GDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRV 359
G Q PG + + PG KG+ + APG G
Sbjct: 567 GPSGPRGQ---------------PGVMGF--------PGPKGN-DGAPGKNGERGGPG-- 600
Query: 360 GDGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHG-EASRGAAEPEAQLSNHLA 418
G GPQ PG++ E + P GP G+ P P G + G P + +
Sbjct: 601 GPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPP--GPQGLQGLPGTGGPPGE-NGKPG 657
Query: 419 EEGPAEGSGEAARVNGRREDGEASE 443
E GP +G G+ + G E
Sbjct: 658 EPGPKGDAGAPGAPGGKGDAGAPGE 682
Score = 79.3 bits (194), Expect = 1e-14
Identities = 122/435 (28%), Positives = 150/435 (34%), Gaps = 56/435 (12%)
Query: 5 AEPEGVAPGPQGP--PEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGG 62
A P G +PG +G P PA PG+ G GG+ E E E P G A GG
Sbjct: 791 AGPRG-SPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAG--PPGG 847
Query: 63 GGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPR 122
GP P G +G GE G P A P GA+ + G G G P
Sbjct: 848 SGPAGPP-----GPQGVKGE-RGSPGGPGAAGFP-------GARGLPGPPGSNGNPGPPG 894
Query: 123 GEAQREPEDSAAPERQEEAEQRPEV--PEGSAS--GEAGDSVDAEGPLGDNIEAEGPAGD 178
+ P A P V P+G A GE G S A+GP G A GP G
Sbjct: 895 PSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKG-SPGAQGPPG----APGPLGI 949
Query: 179 S--VEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPA 236
+ A G G GP G + GP G ++ P + + E GP
Sbjct: 950 AGITGARGLAGPP-GMPGPRG----SPGPQGVKGESGKPGANGLSGE---------RGPP 995
Query: 237 GDS--VDAEGRVGDSVEAGDPAGDGVEA--GVPAGDSVEAEGPAGDSMDAEGPAGRARRV 292
G G G+ G+P DG+ G P G E + + A G G V
Sbjct: 996 GPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPV 1055
Query: 293 SGEPQQSGD-GSLSPQAEA-IEVAAGESAGRSPGELAWDAAEEAE--VPGVKGSEEAAPG 348
G +SGD G P A AG P D E E G+KG PG
Sbjct: 1056 -GPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKG-HRGFPG 1113
Query: 349 DARADAGEDRVG-DGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHGEASRGAA 407
+ A G G PG R P GP ++ G P P +RG
Sbjct: 1114 NPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSG-HPGPIGPPGPRGNRGER 1172
Query: 408 EPEAQLSNHLAEEGP 422
E H + GP
Sbjct: 1173 GSEGS-PGHPGQPGP 1186
Score = 34.7 bits (78), Expect = 0.30
Identities = 27/69 (39%), Positives = 31/69 (44%), Gaps = 12/69 (17%)
Query: 12 PGPQGPPEVPAPLAER-----PGEPGAAGGEAEGPEGSEGAEEAPRGAAAV-----KEAG 61
PGP GPP ER PG PG G GP G+ G GAAA+ ++AG
Sbjct: 1157 PGPIGPPGPRGNRGERGSEGSPGHPGQPG--PPGPPGAPGPCCGGVGAAAIAGIGGEKAG 1214
Query: 62 GGGPDRGPE 70
G P G E
Sbjct: 1215 GFAPYYGDE 1223
>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
Length = 1073
Score = 88.2 bits (217), Expect = 2e-17
Identities = 149/527 (28%), Positives = 189/527 (35%), Gaps = 104/527 (19%)
Query: 7 PEGVAPGPQGP------PEVPAP--LAERPGEPGAAGGE----AEGPEGSEGAEEAPRGA 54
P PG QGP P +P L RPGE G G A+G EG+ GA A
Sbjct: 341 PHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNP 400
Query: 55 AAVKEAGGGGPDRGPEAEA----RGTRGAHGETEAEEGAP--EGAEVPQGGEETSGAQQV 108
A G GP P + RGT G GE E+GA EG+ P G GA +
Sbjct: 401 GAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGE-RGEKGAAGEEGSPGPVGPRGDPGAPGL 459
Query: 109 EGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGD 168
G PG+G GEP R P + P +P GS + GP G
Sbjct: 460 PGP-PGKGKDGEP---GLRGSPGLPGPLGTKGDRGAPGIP-GSPGSRGDPGIGVAGPPGP 514
Query: 169 NIEAEGPAGDSVEAEGR-VGDSVDAEGPAG-DSVDAEGPLGD-NIQAE--------GPAG 217
+ GP GD R + +GPAG D + + GD N+ A+ GP G
Sbjct: 515 S----GPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPG 570
Query: 218 -----------------DSVDAEGRVGDS--------VDAEGPAGDSVD--AEGRVGDSV 250
EG+ G++ GP G + A+G VG
Sbjct: 571 LPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKG 630
Query: 251 EAGDPAGDGV-----EAGVPAGDSVE-AEGPAG--DSMDAEGPAGRARR-----VSGEPQ 297
+ G P G G P D + A GP G S EGP G + GE
Sbjct: 631 DQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG 690
Query: 298 QSG-DGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKG--SEEAAPGDARADA 354
+ G DG P E + AGE PG + A PG KG + APG
Sbjct: 691 KEGRDGKPGPPGEPGK--AGE-----PGLPGPEGARGP--PGFKGHTGDSGAPGPR---- 737
Query: 355 GEDRVGDGPQQE--PGEDEERRERSPEGPREEEAAGGEEESPDS----SPHGEASRGAAE 408
GE P QE PG+D + P+GP+ G+ SP S P G + ++
Sbjct: 738 GESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSK 797
Query: 409 PE---AQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRALGQEHD 452
E L L GP GE G+ EP G+ D
Sbjct: 798 GENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGD 844
Score = 79.7 bits (195), Expect = 8e-15
Identities = 129/477 (27%), Positives = 158/477 (33%), Gaps = 64/477 (13%)
Query: 13 GPQGPPEVPA------PLAERPGEPGAAGGEAE-GPEGSEGAEEAPRGAAAVKEAGGGGP 65
GP GPP +P P PGE G G + + G G G + P E G GP
Sbjct: 325 GPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPG------ELGPQGP 378
Query: 66 DRGPEAEARGTRGAHGETEA--EEGAPE--GAEVPQGGEETSGAQQVEGASPGRGAQGEP 121
P A +G GAHG A GAP GA P G + GA + G G +GE
Sbjct: 379 TGPPGA--KGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEK 436
Query: 122 RGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAG--DSVDAEGPLGDNIEAEGPAGDS 179
+ P A P P GE G S GPLG + G G
Sbjct: 437 GAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGD-RGAPGIP 495
Query: 180 VEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQ-----------AEGPAG-DSVDAEGRVG 227
R + GP G S GP GD +GPAG D + + G
Sbjct: 496 GSPGSRGDPGIGVAGPPGPS----GPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPG 551
Query: 228 D------SVDAEGPAGDS--VDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDS 279
D V + P G G GD G P +G E GP G
Sbjct: 552 DINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPG-- 609
Query: 280 MDAEGPAGR--ARRVSGEPQQSGD-------GSLSPQAEAIEVAAGESAGRS-PGELAWD 329
GP G R GE Q GD G + P A AG + P +
Sbjct: 610 --IAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGS 667
Query: 330 AAEEAEVPGVKGSEEAAPGDARADAGEDRVG-DGPQQEPGEDEERRERSPEGPREEEAAG 388
+E PG +G PG + E R G GP EPG+ E PEG R
Sbjct: 668 PGKEGP-PGPQG-PSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFK 725
Query: 389 GEE-ESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEP 444
G +S P GE+ + L + GP G ++G P
Sbjct: 726 GHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSP 782
Score = 71.6 bits (174), Expect = 2e-12
Identities = 123/457 (26%), Positives = 166/457 (36%), Gaps = 85/457 (18%)
Query: 12 PGPQGPPEVPAPLAER--PGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGP 69
PGP G P +P ++ PG+PG G E + E P G A GP
Sbjct: 566 PGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIA------------GP 613
Query: 70 EAEARGTRGAHGET--EAEEGAP--EGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEA 125
+ ++G RGA GE + ++G P G P G GA + GA+ G QG P E
Sbjct: 614 QG-SQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEG 672
Query: 126 QREPEDSAA------PERQEEAEQRPEVP-EGSASGEAG--DSVDAEGPLG-----DNIE 171
P+ + E +E + +P P E +GE G A GP G +
Sbjct: 673 PPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSG 732
Query: 172 AEGPAGDSVEA-----EGRVGDSVDAEGPAGDS--VDAEGPLGDNIQA-----EGPAGDS 219
A GP G+S EG G D GP G GP G N GP+G +
Sbjct: 733 APGPRGESGAMGLPGQEGLPGKDGDT-GPTGPQGPQGPRGPPGKNGSPGSPGEPGPSG-T 790
Query: 220 VDAEGRVGDS--------VDAEGPAGDSVDA-----------EGRVGDSVEAGDPAGDGV 260
+G G++ + GP G+ + G G E GDP G
Sbjct: 791 PGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKG- 849
Query: 261 EAGVPAGDSVEAE----GPAGDS--MDAEGPAGRARRVS--GEPQQSGDGSL---SPQAE 309
+ G P G + G G + M +G G V G P Q G L SP E
Sbjct: 850 DKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSME 909
Query: 310 AIEVAAGESAGRS-PGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGD-GPQQEP 367
+ E G+ LA+ A+ P S + PG + G GP EP
Sbjct: 910 TLRRLIQEELGKQLETRLAYLLAQMP--PAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEP 967
Query: 368 GEDEERRERSPEGP---REEEAAGGEEESPDSSPHGE 401
G + P GP + E A G+ +P GE
Sbjct: 968 GRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGE 1004
Score = 60.5 bits (145), Expect = 5e-09
Identities = 120/434 (27%), Positives = 163/434 (37%), Gaps = 93/434 (21%)
Query: 1 MAEAAEPEGVA--------PGPQGPPEVPAPLAER-----------PGEPGAAGGEAEGP 41
+A AA P G+ PGPQGP +P E PGEPG AG G
Sbjct: 655 IAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAG--EPGL 712
Query: 42 EGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGAHG----ETEAEEGAPEGAEVPQ 97
G EGA P ++G GP RG E+ A G G G + + P+G + P+
Sbjct: 713 PGPEGARGPPGFKGHTGDSGAPGP-RG-ESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPR 770
Query: 98 GGEETSGAQQVEG-----ASPG-RGAQGE-----------PRGEAQREPEDSAAPERQEE 140
G +G+ G +PG +G++GE PRG EP + P + E
Sbjct: 771 GPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPG-EPGEKGVPGK-EG 828
Query: 141 AEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDS- 199
+P P GE GD G GD +GP G +G+ GD G G +
Sbjct: 829 VPGKPGEP--GFKGERGDP----GIKGD----KGPPG----GKGQPGDP-GIPGHKGHTG 873
Query: 200 -VDAEGPLGDNIQAEGPAGDSVDAEGRVG-DSVDAEGPAGDSV----------DAEGRVG 247
+ +G G+N GP G G+ G + E P+ +++ E R+
Sbjct: 874 LMGPQGLPGEN----GPVGPP-GPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLA 928
Query: 248 DSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQ 307
+ PA G P GP G +G GRA + GEP + G G L
Sbjct: 929 YLLAQMPPAYMKSSQGRPG-----PPGPPGK----DGLPGRAGPM-GEPGRPGQGGLEGP 978
Query: 308 AEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEP 367
+ I A PG E PG+ G + PG A+ G + GPQ E
Sbjct: 979 SGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPG-QPGEPGYAK--DGLPGI-PGPQGET 1034
Query: 368 GEDEERRERSPEGP 381
G P GP
Sbjct: 1035 GPAGHPGLPGPPGP 1048
Score = 40.8 bits (94), Expect = 0.004
Identities = 38/123 (30%), Positives = 44/123 (35%), Gaps = 11/123 (8%)
Query: 12 PGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVK-EAGGGGPDRGPE 70
PGP GPP + G PG AG E +G E P G K E G G P
Sbjct: 946 PGPPGPPG-------KDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG 998
Query: 71 AEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQREPE 130
RG G G + G P A+ G G Q G + G G P Q +P
Sbjct: 999 VGLRGEMGPPG-IPGQPGEPGYAK--DGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPS 1055
Query: 131 DSA 133
A
Sbjct: 1056 QCA 1058
Score = 38.1 bits (87), Expect = 0.027
Identities = 84/329 (25%), Positives = 105/329 (31%), Gaps = 73/329 (22%)
Query: 125 AQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEG 184
A RE D P + V +G A G G + P + P G E
Sbjct: 163 ASRESLDLLGPR----TDPWENVDQG-AQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSA 217
Query: 185 RVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAE- 243
+G +GPA DA I A A G G+ + P + E
Sbjct: 218 ALG----TQGPADQRADARASC---ILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEI 270
Query: 244 ------GRVGDSVEAGDPAGDGV--------------EAGVPA-----GDSVEAEGPAGD 278
GR G+ EAG P G E G+P G+ EA GPAG
Sbjct: 271 GEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEA-GPAGP 329
Query: 279 SMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRS--PGELAWDAAEEAEV 336
G G + P+ G+ P+ E + G PGEL
Sbjct: 330 P----GLPGTTSLFTPHPRMPGEQG--PKGEKGDPGLPGEPGLQGRPGELGPQGPTGP-- 381
Query: 337 PGVKGSEEA--APGDARADAGEDRVG-------------DGPQQEPGEDEERRERS---- 377
PG KG E A APG A VG G + PG+D ER E+
Sbjct: 382 PGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGE 441
Query: 378 -----PEGPREEEAAGGEEESPDSSPHGE 401
P GPR + A G P GE
Sbjct: 442 EGSPGPVGPRGDPGAPGLPGPPGKGKDGE 470
>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
Length = 1745
Score = 86.7 bits (213), Expect = 7e-17
Identities = 133/447 (29%), Positives = 170/447 (38%), Gaps = 100/447 (22%)
Query: 13 GPQGPPEVPAPLAER--------PGEPGAAGGEAE-GPEGSEGAEEAPRGAAAVKEAGGG 63
GP GP P R PG+PG G + + GP G GA +P + AGG
Sbjct: 962 GPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGI 1021
Query: 64 G-----PDRGPEAEA-----RGTRGAHGETEAEEG--------APEGAEVPQGGEETS-- 103
G GP A RG RG G T ++G P GA P G E
Sbjct: 1022 GLPGQSGSEGPVGPAGKKGSRGERGPPGPT-GKDGIPGPLGPLGPPGAAGPSGEEGDKGD 1080
Query: 104 -GAQQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDS--- 159
GA +G+ +G G P R P P + A+ R P G+ GD
Sbjct: 1081 VGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPP--GLFGQKGDDGVR 1138
Query: 160 --VDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAG 217
V GP G GP G+ +G VGD V + GP G A GP G +GP G
Sbjct: 1139 GFVGVIGPPGLQ-GLPGPPGE----KGEVGD-VGSMGPHG----APGPRG----PQGPTG 1184
Query: 218 DSVDAEGRVG--DSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGP 275
+EG G V G G+ +G GD+ + G P G+ P GD + +G
Sbjct: 1185 ----SEGTPGLPGGVGQPGAVGE----KGERGDAGDPGPPGAPGIPG--PKGD-IGEKGD 1233
Query: 276 AGDSMDAEGPAGRARRVSGEPQQSG-DGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEA 334
+G S A GP G+ G P + G GS+ P PG+L
Sbjct: 1234 SGPS-GAAGPPGK----KGPPGEDGAKGSVGPTG-------------LPGDLG-----PP 1270
Query: 335 EVPGVKGSEEAAPGDARADAGEDRVGDGP---QQEPGEDEERRERSPEGPREEEAAGGE- 390
PGV G + +PG+ + D G D G GP EPG +R P G E GE
Sbjct: 1271 GDPGVSGI-DGSPGE-KGDPG-DVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEK 1327
Query: 391 ----EESPDSSPHGEASRGAAEPEAQL 413
E PD P GA P ++
Sbjct: 1328 GAKGEPGPDGPPGRTGPMGARGPPGRV 1354
Score = 85.5 bits (210), Expect = 1e-16
Identities = 143/514 (27%), Positives = 188/514 (36%), Gaps = 128/514 (24%)
Query: 4 AAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGG 63
A P+GV GP GPP P + PG PG AG G G +G P + G
Sbjct: 396 APGPQGVV-GPSGPPGPPGFPGD-PGPPGPAG--LPGIPGIDGIRGPPGTVIMMPFQFAG 451
Query: 64 GPDRGP-------EAEA---------RGTRGAHGET--EAEEGAP--------EGAEVPQ 97
G +GP +A+A +G G G T G P EGAE PQ
Sbjct: 452 GSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQ 511
Query: 98 GGEETSGAQQVEGASPGR-GAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEA 156
G G PGR G G P + R P+ + P +P G+
Sbjct: 512 GPRGLQGPH----GPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLP--GEKGQR 565
Query: 157 GD--SVDAEGPLGDNIE--AEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQA 212
GD V GP G++ E AEGP G + G+ G+ GP G GP G
Sbjct: 566 GDFGHVGQPGPPGEDGERGAEGPPGPT----GQAGEP----GPRG----LLGPRGSPGPT 613
Query: 213 EGPAGDSVD----AEGRVGDSVDAEGPAGDSVD--------AEGRVGDSVEAGDPAGDGV 260
P +D A+G VG + GP G + +G +G E G P G+
Sbjct: 614 GRPGVTGIDGAPGAKGNVGPPGEP-GPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGI 672
Query: 261 EAGVPAGDSVEA----EGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAG 316
G+P D EGP G+ A+GP G A G P G + G
Sbjct: 673 P-GLPGSDGPLGHPGHEGPTGEK-GAQGPPGSA----GPPGYPGPRGVK----------G 716
Query: 317 ESAGRSPGELAWDAAEEAE--VPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERR 374
S R L + E+ E PG KG D G G Q +PG R
Sbjct: 717 TSGNRG---LQGEKGEKGEDGFPGFKG-----------DVGLK----GDQGKPGAPGPRG 758
Query: 375 ERSPEGPREEEAAGGEEESPDSSPHGEASR----------GAAEPEAQLS-----NHLAE 419
E PEGP+ + GEE P S+ GE + G P+ + + E
Sbjct: 759 EDGPEGPKGQAGQAGEEGPPGSA--GEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGE 816
Query: 420 EGPAEGSGEAARVNGRR----EDGEASEPRALGQ 449
+G + +G+ + G R GE +P A GQ
Sbjct: 817 KGKSGKTGQPG-LEGERGPPGSRGERGQPGATGQ 849
Score = 76.3 bits (186), Expect = 9e-14
Identities = 97/317 (30%), Positives = 121/317 (38%), Gaps = 51/317 (16%)
Query: 12 PGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPD----- 66
PGP G +P PL G PGAAG G EG +G AP + + G GP
Sbjct: 1048 PGPTGKDGIPGPLGPL-GPPGAAG--PSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGI 1104
Query: 67 RGPEAEARGTRGAHGETEAEEGAP-----EGAEVPQGGEETSGAQQVEGASPGRGAQGEP 121
RGP A G GA G + G P +G + +G G ++G G +GE
Sbjct: 1105 RGP-AGHPGPPGADG-AQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEV 1162
Query: 122 RGEAQREPEDSAAPERQE---EAEQRPEVPEG-------SASGEAGDSVDAEGPLGDNIE 171
P + P + +E P +P G GE GD+ D P I
Sbjct: 1163 GDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGI- 1221
Query: 172 AEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDS-- 229
GP GD G GDS GP+G A GP G +GP G+ A+G VG +
Sbjct: 1222 -PGPKGDI----GEKGDS----GPSG----AAGPPG----KKGPPGED-GAKGSVGPTGL 1263
Query: 230 VDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRA 289
GP GD G G E GDP G A A GP G GP+G
Sbjct: 1264 PGDLGPPGDP-GVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPG----KRGPSGHM 1318
Query: 290 RRVSGEPQQSGDGSLSP 306
R E ++ G P
Sbjct: 1319 GREGREGEKGAKGEPGP 1335
Score = 68.6 bits (166), Expect = 2e-11
Identities = 94/308 (30%), Positives = 124/308 (40%), Gaps = 54/308 (17%)
Query: 12 PGPQGPPEVPAPLAERPGEPGAAG-GEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPE 70
PGP G P +P P + GE G +G A GP G +G +V G G D GP
Sbjct: 1213 PGPPGAPGIPGPKGD-IGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPG-DLGPP 1270
Query: 71 AEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQREPE 130
+ G G G + E+G P GG GA GA PG + P G RE
Sbjct: 1271 GDP-GVSGIDG-SPGEKGDPGDV----GGPGPPGASGEPGA-PGPPGKRGPSGHMGREGR 1323
Query: 131 DSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSV 190
+ E+ + E P+ P G GP+G A GP G V EG G
Sbjct: 1324 EG---EKGAKGEPGPDGPPGRT-----------GPMG----ARGPPG-RVGPEGLRG--- 1361
Query: 191 DAEGPAGDS--VDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDS--VDAEGRV 246
GP G+ + A G +G GP G S G GD+ GP G+ + G +
Sbjct: 1362 -IPGPVGEPGLLGAPGQMG----PPGPLGPS-GLPGLKGDT----GPKGEKGHIGLIGLI 1411
Query: 247 GDSVEAGDPAGDGVEAGV-----PAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGD 301
G EAG+ G+ GV P GD GP G S+ GP G A + + +
Sbjct: 1412 GPPGEAGEKGDQGL-PGVQGPPGPKGDP-GPPGPIG-SLGHPGPPGVAGPLGQKGSKGSP 1468
Query: 302 GSLSPQAE 309
GS+ P+ +
Sbjct: 1469 GSMGPRGD 1476
Score = 43.9 bits (102), Expect = 5e-04
Identities = 30/92 (32%), Positives = 38/92 (41%), Gaps = 11/92 (11%)
Query: 12 PGPQGPPEVPAPLAE--RPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGP 69
PGP+G P P P+ PG PG AG P G +G++ +P + G GP P
Sbjct: 1432 PGPKGDPGPPGPIGSLGHPGPPGVAG-----PLGQKGSKGSPGSMGPRGDTGPAGPPGPP 1486
Query: 70 EAEARGTRGAHGETEAEEGAPEGAEVPQGGEE 101
A A HG P V +GG E
Sbjct: 1487 GAPAE----LHGLRRRRRFVPVPLPVVEGGLE 1514
Score = 39.3 bits (90), Expect = 0.012
Identities = 109/418 (26%), Positives = 136/418 (32%), Gaps = 95/418 (22%)
Query: 14 PQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEA 73
PQG PE P RP G G +G G +G +G KE P
Sbjct: 235 PQGEPETP-----RPRRKGKGKGRKKG-RGRKG-----KGRKKNKEIWTSSPPPDSAENQ 283
Query: 74 RGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQV---EGASPGRGAQ-GEPRGEAQREP 129
T ET A P + T+G P G + G +A RE
Sbjct: 284 TSTDIPKTETPAPNLPPTPTPLVVTSTVTTGLNATILERSLDPDSGTELGTLETKAARED 343
Query: 130 ED----SAAPE-RQEEAEQRPEVPEGSASGEAGDSVDA---------EGPLGDNIEAEGP 175
E+ + P+ R E R + +GE G + EGP G A GP
Sbjct: 344 EEGDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPG----APGP 399
Query: 176 AGDSVEAEGRVG-----DSVDAEGPAG----DSVDA-EGPLGDNIQA---------EGPA 216
G V G G GPAG +D GP G I +GP
Sbjct: 400 QG-VVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPP 458
Query: 217 GDSVDAEGRV---GDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAE 273
A+ + + +GP G V GR G G P G E AE
Sbjct: 459 VSFQQAQAQAVLQQTQLSMKGPPG-PVGLTGRPGPVGLPGHPGLKGEEG---------AE 508
Query: 274 GPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSP-GELAWDAAE 332
GP G +GP G RV + DG A G P G+ +D
Sbjct: 509 GPQG-PRGLQGPHGPPGRVGKMGRPGADG-----------ARGLPGDTGPKGDRGFDG-- 554
Query: 333 EAEVPGVKGSEEAAPGDARADAGEDRVGD-GPQQEPGEDEERRERSPEGPREEEAAGG 389
+PG+ G + R D G VG GP PGED ER P GP + G
Sbjct: 555 ---LPGLPGEK-----GQRGDFG--HVGQPGP---PGEDGERGAEGPPGPTGQAGEPG 599
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 84.3 bits (207), Expect = 3e-16
Identities = 139/487 (28%), Positives = 180/487 (36%), Gaps = 83/487 (17%)
Query: 2 AEAAEPEGVA--PGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKE 59
A AA P G+ PGPQGPP PA PGE G G G +G +G P A V
Sbjct: 1095 AGAAGPIGIPGRPGPQGPPG-PAGEKGAPGEKGPQG--PAGRDGLQGPVGLPGPAGPVGP 1151
Query: 60 AGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQG 119
G G D+G E G +G+ G+ + E+G P G PQG G +G RG QG
Sbjct: 1152 PGEDG-DKGEIGEP-GQKGSKGD-KGEQGPP-GPTGPQGPIGQPGPSGADGEPGPRGQQG 1207
Query: 120 EPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGD--SVDAEGPLGDNIEAEGPAG 177
+ P P + P P GE GD + GP G + P
Sbjct: 1208 LFGQKGDEGPRGFPGPPGPVGLQGLPGPP--GEKGETGDVGQMGPPGPPGPRGPSGAPGA 1265
Query: 178 DSVEAE-GRVGDSVDAEGPAGDSVDAEGP-LGDNIQAEGPAGDSVDAEGRVGDSVDA--- 232
D + G +G+ A G G+ +A P L GP G+ + +G G S A
Sbjct: 1266 DGPQGPPGGIGNP-GAVGEKGEPGEAGEPGLPGEGGPPGPKGERGE-KGESGPSGAAGPP 1323
Query: 233 --EGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRAR 290
+GP GD +G G GDP G E G PAG +GP GD D +G G+
Sbjct: 1324 GPKGPPGDD-GPKGSPGPVGFPGDPGPPG-EPG-PAGQ----DGPPGDKGD-DGEPGQTG 1375
Query: 291 RV--SGEPQQSGD-------GSLSPQAEAIEVAAGESAGRS--PGELAWDAAEEAE---- 335
+GEP SG G P+ E A AG PG+ + A
Sbjct: 1376 SPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPG 1435
Query: 336 ------VPGVKGSEEAAPGDARADAGEDRVG----------DGPQQE------------P 367
+PG G E+ PG D +G GP+ E P
Sbjct: 1436 PDGLRGIPGPVG-EQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPP 1494
Query: 368 GEDEERRERSPEGPREEEAAGGEE-----ESPDSSPHGEASRGAAEPEAQLSNHLAEEGP 422
GE E+ +R GP+ GE+ P P G P+ + GP
Sbjct: 1495 GEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGS----SGP 1550
Query: 423 AEGSGEA 429
GEA
Sbjct: 1551 TGPKGEA 1557
Score = 73.9 bits (180), Expect = 4e-13
Identities = 128/489 (26%), Positives = 174/489 (35%), Gaps = 105/489 (21%)
Query: 12 PGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAP--RGAAAVK----EAGGGGP 65
PGPQGP P P + G G G +G +G +G + P +G +K E G GP
Sbjct: 780 PGPQGPIGYPGPRGVK-GADGIRG--LKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGP 836
Query: 66 --DRGPEAEARGTRGAHGET--------EAEEGAP-----EGAEVPQGGEETSGAQQVEG 110
+ GPE +G G +G+ + + G P G + P+G G G
Sbjct: 837 RGEDGPEGP-KGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANG 895
Query: 111 ASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNI 170
GRG G+P QR P +P P+G++ G+ GP G+
Sbjct: 896 EKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPG-PKGNSGGDG-----PAGPPGE-- 947
Query: 171 EAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLG-DNIQAEGPAGDSVDAEGRVGDS 229
GP G +G G GP G GP G D + +G+ G
Sbjct: 948 --RGPNG----PQGPTG----FPGPKG----PPGPPGKDGLPGHPGQRGETGFQGKTGPP 993
Query: 230 -----VDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEG 284
V +GP G++ G +G+ G P G E G+P EG GD G
Sbjct: 994 GPPGVVGPQGPTGET----GPMGERGHPGPPGPPG-EQGLPG--LAGKEGTKGD----PG 1042
Query: 285 PAGRARRVSGEPQQ---SGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKG 341
PAG + G P GD L A+ + E PG A PG +G
Sbjct: 1043 PAGLPGK-DGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPG--------PAGSPGERG 1093
Query: 342 SEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHGE 401
AA GP PG + P GP E+ A GE+ P G
Sbjct: 1094 PAGAA---------------GPIGIPGRP---GPQGPPGPAGEKGAPGEK-----GPQGP 1130
Query: 402 ASRGAAEPEAQLSNHLAEEGP--AEGS----GEAARVNGRREDGEASEPRALGQEHDITL 455
A R + L GP +G GE + + + GE P G + I
Sbjct: 1131 AGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQ 1190
Query: 456 FVKAGYDGE 464
+G DGE
Sbjct: 1191 PGPSGADGE 1199
Score = 73.6 bits (179), Expect = 6e-13
Identities = 136/467 (29%), Positives = 166/467 (35%), Gaps = 73/467 (15%)
Query: 12 PGPQGP------PEVPAPLAER-----PGEPGAAGGEAEGPEGSEGAEEAPRGAAAVK-- 58
PG QGP P P E+ PG+PG G GP G G E PRG
Sbjct: 876 PGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRG--QRGPTGPRG-ERGPRGITGKPGP 932
Query: 59 --EAGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSG--AQQVEGASPG 114
+GG GP GP E RG G G T P+G P G + G Q+ E G
Sbjct: 933 KGNSGGDGP-AGPPGE-RGPNGPQGPTGFP--GPKGPPGPPGKDGLPGHPGQRGETGFQG 988
Query: 115 R-GAQGEPRGEAQREPEDSAAPERQEEAEQRPEVP-EGSASGEAGDSVDAEGPLGDNIEA 172
+ G G P + P P + P P E G AG EG GD A
Sbjct: 989 KTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGK----EGTKGDPGPA 1044
Query: 173 EGPAGDSVEA-EGRVGDSVDAEGPAG--DSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDS 229
P D G GD GP G EGP G GPAG S G G
Sbjct: 1045 GLPGKDGPPGLRGFPGDR-GLPGPVGALGLKGNEGPPGP----PGPAG-SPGERGPAG-- 1096
Query: 230 VDAEGPAG--DSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAG 287
A GP G +G G + E G P G + PAG +GP G GPAG
Sbjct: 1097 --AAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQG--PAGRD-GLQGPVG----LPGPAG 1147
Query: 288 RARRVSGEPQQSGD-GSLS-PQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEA 345
G P + GD G + P + + GE P + PG G++
Sbjct: 1148 PV----GPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQ----PGPSGAD-G 1198
Query: 346 APGDARADAGEDRVGD-GPQQEPGEDEERRERSPEGPREEEAAGGE--EESPDSSPHGEA 402
PG + GD GP+ PG + GP E+ G+ + P P
Sbjct: 1199 EPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRG 1258
Query: 403 SRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRALGQ 449
GA + +GP G G V + E GEA EP G+
Sbjct: 1259 PSGAPGADGP-------QGPPGGIGNPGAVGEKGEPGEAGEPGLPGE 1298
Score = 64.7 bits (156), Expect = 3e-10
Identities = 113/429 (26%), Positives = 155/429 (36%), Gaps = 71/429 (16%)
Query: 12 PGPQGPPEVPAPLAERPGEPGAAGGEAE-GPEGSEGAEEAPRGAAAVKEAGGGGPDRGPE 70
PGP GPP P G+ G G + E GP G G E PRG K G GP P
Sbjct: 648 PGPSGPPGPP-------GDDGERGDDGEVGPRGLPG-EPGPRGLLGPK--GPPGPPGPP- 696
Query: 71 AEARGTRGAHGETEAEEGA-PEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQREP 129
G G G+ + P+G P G + GAQ + G G GE +G +
Sbjct: 697 ----GVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGE-KGPLGKPG 751
Query: 130 EDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLG----------DNIEA-EGPAGD 178
E P G G+ +GP+G D I +G G+
Sbjct: 752 LPGMPGADGPPGHPGKEGPPGEKGGQGPPG--PQGPIGYPGPRGVKGADGIRGLKGTKGE 809
Query: 179 SVEAEGRVGDSVDAEGPAGD--SVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPA 236
E +G G D G GD + GP G+ +GP G +GR G + D GP
Sbjct: 810 KGE-DGFPGFKGDM-GIKGDRGEIGPPGPRGE----DGPEG----PKGRGGPNGD-PGPL 858
Query: 237 GDSVDAEGRVGDSVEAGDPAGDGVEA--GVPAGDSVEAEGPAGDSMDAEGPAGRARRVSG 294
G + +G++G G P G + G P E + GP G+ R +G
Sbjct: 859 GPPGE-KGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQ-RGPTG 916
Query: 295 EPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAE-EAEVPGVKG-----SEEAAPG 348
+ G ++ + + G+ PGE + + PG KG ++ PG
Sbjct: 917 PRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPG 976
Query: 349 --DARADAG-EDRVG----------DGPQQEPGEDEERRERSPEGPREEEA----AGGEE 391
R + G + + G GP E G ER P GP E+ AG E
Sbjct: 977 HPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEG 1036
Query: 392 ESPDSSPHG 400
D P G
Sbjct: 1037 TKGDPGPAG 1045
Score = 58.2 bits (139), Expect = 3e-08
Identities = 90/308 (29%), Positives = 113/308 (36%), Gaps = 55/308 (17%)
Query: 3 EAAEP----EGVAPGPQGP-----PEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRG 53
EA EP EG PGP+G P+ A PG G G + GP+GS G P
Sbjct: 1289 EAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDD--GPKGSPGPVGFPGD 1346
Query: 54 AAAVKE---AGGGGP--DRGPEAEARGTRGAHGET-EAEEGAPEGAEVPQGGEETSGAQQ 107
E AG GP D+G + E G G+ G T E P G P G G Q
Sbjct: 1347 PGPPGEPGPAGQDGPPGDKGDDGEP-GQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQG 1405
Query: 108 VEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRP-EVPEGSASGEAGDSVDAEGPL 166
+GA G +G P P+ + + P V E G G +GP
Sbjct: 1406 EKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPG----PDGPP 1461
Query: 167 GDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDS-----VDAEGPLGDNIQAEGPAGDSVD 221
G GP G G GDS GP G+ + GP G+ +G GD
Sbjct: 1462 G----PMGPPG----LPGLKGDS----GPKGEKGHPGLIGLIGPPGE----QGEKGDR-G 1504
Query: 222 AEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMD 281
G G S GP G+ +G G S G P G+ + + GP G +
Sbjct: 1505 LPGPQGSS----GPKGE----QGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGE 1556
Query: 282 A--EGPAG 287
A GP G
Sbjct: 1557 AGHPGPPG 1564
Score = 52.0 bits (123), Expect = 2e-06
Identities = 118/494 (23%), Positives = 166/494 (33%), Gaps = 97/494 (19%)
Query: 3 EAAEPEGVAPGPQGPP--------EVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGA 54
E E G P P P EVP L P E A PE SEGA +
Sbjct: 281 EDPEDLGKEPTPSKKPVEAAKETTEVPEELTPTPTEA------APMPETSEGAGKE---- 330
Query: 55 AAVKEAGGGGPDRGPEAEARGTRG----AHGETEAEEGAPE----GAEVPQGGEETSGAQ 106
++ G G D P + +GE E P GAE+P +TS +
Sbjct: 331 ---EDVGIGDYDYVPSEDYYTPSPYDDLTYGEGEENPDQPTDPGAGAEIPTSTADTSNSS 387
Query: 107 QVEGASPGRGA---QGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAE 163
PG GA +GE E R +++ + E+ G + +
Sbjct: 388 N-PAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQDTIYEGIG 446
Query: 164 GPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAE 223
GP G+ + PA + + EGP G EGP G GP G ++
Sbjct: 447 GPRGEKGQKGEPA--------IIEPGMLIEGPPGP----EGPAG----LPGPPG-TMGPT 489
Query: 224 GRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVP----AGDSVEAEGPAGDS 279
G+VGD + P GR G G P G +P G ++GP +
Sbjct: 490 GQVGDPGERGPP--------GRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSA 541
Query: 280 MDAE-------------GPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGEL 326
+++ GPAG ++G P G P + ++ G+ + P +
Sbjct: 542 QESQAQAILQQARLALRGPAG-PMGLTGRPGPVGP----PGSGGLKGEPGDVGPQGPRGV 596
Query: 327 AWDAAEEAEVPGVKGSEEAAPGDARADAGE-----DRVGDGPQQEPGEDEERRERSPEGP 381
+ PG +G A AR G+ DR DG PGE R + P GP
Sbjct: 597 QGPPGPAGK-PGRRG--RAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGP 653
Query: 382 REEEAAGGE-----EESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRR 436
GE E P P RG P+ GP +G + +
Sbjct: 654 PGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGP----PGPPGPPGVTGMDGQPGPKG 709
Query: 437 EDGEASEPRALGQE 450
G EP GQ+
Sbjct: 710 NVGPQGEPGPPGQQ 723
Score = 32.0 bits (71), Expect = 2.0
Identities = 22/57 (38%), Positives = 25/57 (43%), Gaps = 18/57 (31%)
Query: 13 GPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGP 69
GP GPP +P P PG GA G + GP G +G EAG GP P
Sbjct: 1528 GPPGPPGLPGP----PGPKGAKG--SSGPTGPKG------------EAGHPGPPGPP 1566
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 82.4 bits (202), Expect = 1e-15
Identities = 135/509 (26%), Positives = 187/509 (36%), Gaps = 87/509 (17%)
Query: 4 AAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAE-------GPEGSEG-----AEEAP 51
+A P G +PGPQG P + +PG+PG G + E GP G +G EE
Sbjct: 445 SAGPPG-SPGPQGSTG-PQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGK 502
Query: 52 RGAAAVKEAGGGGPDRGPEAE--ARGTRGAHGE--------TEAEEGAPEGAEVPQGGEE 101
RG + G GP GP E A G RG G + E G P G+ P+G +
Sbjct: 503 RGPRG--DPGTVGPP-GPVGERGAPGNRGFPGSDGLPGPKGAQGERG-PVGSSGPKGSQG 558
Query: 102 TSGAQQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVD 161
G G RG G P + PE P + RP P S+
Sbjct: 559 DPGRPGEPGLPGARGLTGNP---GVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMG 615
Query: 162 AEGPLGDNIEAEGPAGDSVEA-----------EGRVGDS--VDAEGPAGDSVDAEGPLGD 208
GP G + + G G++ A +G VG S V G AG+ + P
Sbjct: 616 LPGPKGSSGD-PGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPT 674
Query: 209 NIQA-EGPAGDSVDAEGRVGD-SVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGV--EAGV 264
Q GP G + G+ GD V + A + G G+ E G+P G+ E G+
Sbjct: 675 GFQGLPGPPGPPGEG-GKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGM 733
Query: 265 PAGDSVE----AEGPAGDSMDAEGPAG-----RARRVSGEPQQSGDGSLSPQAEAIEVAA 315
G + + GP+G D GP G R ++G P GD + A A
Sbjct: 734 AGGHGPDGPKGSPGPSGTPGDT-GPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAG 792
Query: 316 GESAGRSPGEL-----AWDAAEEAEVPGVKG-----SEEAAPGDARADAGEDRVG-DGPQ 364
+ A PG L A E+ E PG +G PG + VG GPQ
Sbjct: 793 NDGARGLPGPLGPPGPAGPTGEKGE-PGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQ 851
Query: 365 ---------QEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQL-- 413
EPGE ++ + GP+ + G P+ P + RG P
Sbjct: 852 GPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPG-PHGPNGVPGLKGGRGTQGPPGATGF 910
Query: 414 ---SNHLAEEGPAEGSGEAARVNGRREDG 439
+ + GPA G A + ++G
Sbjct: 911 PGSAGRVGPPGPAGAPGPAGPLGEPGKEG 939
Score = 78.2 bits (191), Expect = 2e-14
Identities = 137/457 (29%), Positives = 171/457 (37%), Gaps = 90/457 (19%)
Query: 12 PGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPE- 70
PGP+G P +PGE G AG G G+ G + E G GP P
Sbjct: 617 PGPKGSSGDPG----KPGEAGNAG--VPGQRGAPGKD---------GEVGPSGPVGPPGL 661
Query: 71 AEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGE-----A 125
A RG +G G T +G P G P G G Q V G PG PRGE
Sbjct: 662 AGERGEQGPPGPT-GFQGLP-GPPGPPGEGGKPGDQGVPG-DPGAVGPLGPRGERGNPGE 718
Query: 126 QREPEDSAAP-ERQEEAEQRPEVPEGS--ASGEAGDS--VDAEGPLGDN--IEAEGPAGD 178
+ EP + P E+ P+ P+GS SG GD+ +G G+ GP GD
Sbjct: 719 RGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGD 778
Query: 179 SVEAEGRVGDSVDAEGPAGD--SVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPA 236
G +G+ AEG AG+ + GPLG GPAG + G G+ GP
Sbjct: 779 ----RGGIGEK-GAEGTAGNDGARGLPGPLG----PPGPAGPT----GEKGE----PGP- 820
Query: 237 GDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEP 296
G VG G+P G P G +V GP G +G G + GEP
Sbjct: 821 ------RGLVGPPGSRGNPGSRGENG--PTG-AVGFAGPQG----PDGQPG-VKGEPGEP 866
Query: 297 QQSGD-GSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSE--EAAPGDARAD 353
Q GD GS PQ AG P VPG+KG + PG
Sbjct: 867 GQKGDAGSPGPQG-----LAGSPGPHGPN----------GVPGLKGGRGTQGPPGATGFP 911
Query: 354 AGEDRVG-DGPQQEPGEDEERRERSPEGP---REEEAAGGE--EESPDSSPHGEASRGAA 407
RVG GP PG E EGP R + + G + P P G +G
Sbjct: 912 GSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDP 971
Query: 408 EPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEP 444
+ Q GPA +G+ V + GE P
Sbjct: 972 GEDGQPGPD-GPPGPAGTTGQRGIVGMPGQRGERGMP 1007
Score = 77.8 bits (190), Expect = 3e-14
Identities = 129/474 (27%), Positives = 179/474 (37%), Gaps = 80/474 (16%)
Query: 7 PEGVA--PGPQGPPEVPA-----------------PLAERPGEPGAAGGEAEGPEG--SE 45
P+G+A PGP GP VP A R G PG AG A GP G E
Sbjct: 877 PQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAG--APGPAGPLGE 934
Query: 46 GAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGA 105
+E P G + G DRGP A G G G+ E+G P G + P G T+G
Sbjct: 935 PGKEGPPGLRGDPGSHGRVGDRGP-AGPPGGPGDKGD-PGEDGQP-GPDGPPGPAGTTGQ 991
Query: 106 QQVEGASPGRGAQGEP--RGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAE 163
+ + G RG +G P G A + ++ P P GS
Sbjct: 992 RGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGS-----------N 1040
Query: 164 GPLGDNIEAEGPAGD--SVEAEGRVGDSVDA--EGPAG--DSVDAEGPLGDNIQAEGPAG 217
GP+G+ EGPAG+ + +G VG+ D GPAG S A G G + A G AG
Sbjct: 1041 GPVGEP-GPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGP-VGAPGDAG 1098
Query: 218 DSVD--AEGRVGDSVDA--------EGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAG 267
D + G +G A +GP GD D G GD + G G++ G+P
Sbjct: 1099 QRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGD-HGDRGDRGQKGHRGFTGLQ-GLPGP 1156
Query: 268 DSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSP-QAEAIEVAAGESAGRSPGEL 326
E + GP G V ++ G L P + + GE+ P
Sbjct: 1157 PGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGP--- 1213
Query: 327 AWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEA 386
E PG G PG A G D +G DE + PE E++A
Sbjct: 1214 ----PGEPGPPGPPG----PPGHLTAALG-DIMGH-------YDESMPDPLPEF-TEDQA 1256
Query: 387 AGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGE 440
A ++ D H +++ E S +++ PA + + ++ GE
Sbjct: 1257 APDDKNKTDPGVHATLKSLSSQIETMRSPDGSKKHPARTCDDLKLCHSAKQSGE 1310
Score = 76.6 bits (187), Expect = 7e-14
Identities = 127/463 (27%), Positives = 159/463 (34%), Gaps = 53/463 (11%)
Query: 12 PGPQGPPEVPAPLAER--PGEPGAAGGEA-EGPEGSEGAEEAPRGAAAVKEAGGGGPDRG 68
PGP GPP P ER G PG G + +G G G AP G G R
Sbjct: 131 PGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRP 190
Query: 69 PEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQRE 128
A+ G G ++ G G+ P G G Q +G + G GEP
Sbjct: 191 FSAQMAGLDEKSG-LGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMG 249
Query: 129 PEDSAAPERQE-EAEQRPEVPEGSASGEAG--DSVDAEGPLG-----------DNIEAEG 174
P S PE + + E GE G S A G G + EG
Sbjct: 250 PIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEG 309
Query: 175 PAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEG 234
P G+ V A G G++ GP G + A GPLG G G+ GR+G A G
Sbjct: 310 PKGE-VGAPGSKGEA----GPTG-PMGAMGPLG----PRGMPGE----RGRLGPQ-GAPG 354
Query: 235 PAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAE-GPAGDSMDAEGPAGRARRVS 293
G A G G G P G +G P ++ E GP G + EGP G+ R +
Sbjct: 355 QRG----AHGMPGKPGPMG-PLGIPGSSGFPGNPGMKGEAGPTG-ARGPEGPQGQ-RGET 407
Query: 294 GEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELA-WDAAEEAEVPGVKGSEEAAPGDARA 352
G P G L + SPG +A PG +GS P R
Sbjct: 408 GPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGS--TGPQGIRG 465
Query: 353 DAGEDRVGD-----GPQQEPGEDEERRERSPEGPREEEAAGGEEESPDS-SPHGEASRGA 406
G+ V GP+ EPG + P GP EE G P + P G
Sbjct: 466 QPGDPGVPGFKGEAGPKGEPG---PHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERG 522
Query: 407 AEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRALGQ 449
A GP GE V G +P G+
Sbjct: 523 APGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGE 565
Score = 70.5 bits (171), Expect = 5e-12
Identities = 126/466 (27%), Positives = 163/466 (34%), Gaps = 92/466 (19%)
Query: 11 APGPQGPPEVPAPLA-ERPGEPGAAGGEAEGPEGSE-------GAEEAPRGAAAVKEAGG 62
APGP G P P P RP AG + + GS+ PRG ++ G
Sbjct: 172 APGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQG 231
Query: 63 GGPDRGPEAEARGTRGAHGE--TEAEEGAP-----EGAEVPQGGEETSGAQQVEGASPGR 115
G GP E G G G + EG P +G G G GA
Sbjct: 232 GAGPTGPPGEP-GDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFP 290
Query: 116 GAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDS--VDAEGPLGDNIEAE 173
GA G P + R + P + EV + GEAG + + A GPLG
Sbjct: 291 GAPGLPGLKGHRGHKGLEGP--------KGEVGAPGSKGEAGPTGPMGAMGPLG----PR 338
Query: 174 GPAGDSVEAEGRVG-DSVDAEGPAGDSVDAEGPLGD-NIQAEGPAGDSVDAEGRVGDSVD 231
G G+ GR+G + A GP+G I + +G G +
Sbjct: 339 GMPGE----RGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPT-G 393
Query: 232 AEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARR 291
A GP G +G+ G++ G G+ + + A+GP G S GP G A
Sbjct: 394 ARGPEG----PQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTG-SPGTSGPPGSA-- 446
Query: 292 VSGEPQQSG-DGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDA 350
G P G GS PQ I G+ PG VPG KG EA P
Sbjct: 447 --GPPGSPGPQGSTGPQ--GIRGQPGD-----PG-----------VPGFKG--EAGP--- 481
Query: 351 RADAGEDRVGDGPQQEPGEDEERRER------SPEGPREEEAAGGEEESP--DSSPHGEA 402
+ + G + GP PGE+ +R R P GP E A G P D P +
Sbjct: 482 KGEPGPHGI-QGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKG 540
Query: 403 SRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRALG 448
++G E GP SG GE P A G
Sbjct: 541 AQG-------------ERGPVGSSGPKGSQGDPGRPGEPGLPGARG 573
>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
Length = 1125
Score = 81.6 bits (200), Expect = 2e-15
Identities = 134/476 (28%), Positives = 179/476 (37%), Gaps = 91/476 (19%)
Query: 13 GPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAP--RGAAAVKEAGGGGPDRGPE 70
G +G P P P G PGA G +G +G G E P G V E G GP RGPE
Sbjct: 340 GNKGEPGPPGPY----GSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGP-RGPE 394
Query: 71 AEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGAS------------------ 112
G RG G EG P G + +G E +G Q ++G S
Sbjct: 395 G-VPGERGLPG-----EGFP-GPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMG 447
Query: 113 -PGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGD-SVDAEGPLGD-- 168
PG G+QGE + P P Q + EV + +G G + +GP G+
Sbjct: 448 IPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPG 507
Query: 169 NIEAEGPAGDSVE--AEGRVGDS--VDAEGPAGDSVDAE-GPLGDNIQAEGPAGDSVDAE 223
+I G G E A G+ G++ A GP G + GP GD EG G S +
Sbjct: 508 SIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGD----EGKKG-SKGNQ 562
Query: 224 GRVGDSVDAEGPAGDS--VDAEGRVGDSVEA-----GDPAGDGVEAGVPAGDSVEAEGPA 276
G+ G EGP G+ + G G S+ GD G G+ G + GP
Sbjct: 563 GQRG-LPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGI-PGFKGEPGLSIRGPK 620
Query: 277 GDSMDAEGPAGRARRVSGEPQQSGDGSLS-PQAEAIEVAAGESAGRSPGELAWDAAEEAE 335
G +GP G G P GDG P + G R G D + E
Sbjct: 621 G----VQGPRGPV----GAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVG----DTGAKGE 668
Query: 336 VPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAAGGE-EESP 394
PGV+G P R G G Q G+ ++ P GP + G + E+ P
Sbjct: 669 -PGVRG--PPGPSGPR--------GVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGP 717
Query: 395 DSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRALGQE 450
P + + G P Q H GE V + + GE EP + G++
Sbjct: 718 QGFPGPKGTMGHGLP-GQKGEH----------GERGDVGKKGDKGEIGEPGSPGKQ 762
Score = 71.6 bits (174), Expect = 2e-12
Identities = 117/442 (26%), Positives = 165/442 (37%), Gaps = 62/442 (14%)
Query: 28 PGEPGAAGGEAE-GPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEA-RGTRGAHGE--T 83
PG+PG G G +G G + P G A EAG GP P + +G RG G+
Sbjct: 247 PGDPGPPGTHGNPGIKGERGPKGNP-GNAQKGEAGERGPGGIPGYKGDKGERGECGKPGI 305
Query: 84 EAEEGA--PEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEA 141
+ ++G+ P G + P+G + +G G +G +GEP P +
Sbjct: 306 KGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEP------------GPPGPYGS 353
Query: 142 EQRPEVPEGSASGEAGDS--VDAEGPLGDNIEAE-GPAG-DSVEAE-GRVGDSVDAEGPA 196
P + + GE G A GP+G + GP G + V E G G+ GP
Sbjct: 354 PGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGF--PGPK 411
Query: 197 GDSVDAEGPLGDNIQAEGPAGDSVDAE-GRVGDSVDAEGPAG-DSVDAEGRVGDSVEAGD 254
G+ +EGP G +G G S+ E G +G V +GP G + ++G G G
Sbjct: 412 GEK-GSEGPTG----PQGLQGLSIKGEKGDIG-PVGPQGPMGIPGIGSQGEQGIQGPIGP 465
Query: 255 PAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVA 314
P G PAG + M GP G G G P+ E +
Sbjct: 466 PGPQG-----PAGQGLPGSKGEVGQMGPTGPRGPV----------GIGVQGPKGEPGSIG 510
Query: 315 AGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERR 374
G + A EA +PG +G E PG + D +G + G +R
Sbjct: 511 LPGQPGVPGEDGAAGKKGEAGLPGARG-PEGPPGKGQPGPKGD---EGKKGSKGNQGQRG 566
Query: 375 ERSPEGPREEEAAGGEEESPDSS------PHGEASRGAAEPEAQLSNHLAEEGPAEGSGE 428
PEGP+ E G P +S P G+ G P + L+ GP G
Sbjct: 567 LPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRG-GPGIPGFKGEPGLSIRGPKGVQGP 625
Query: 429 AARVN--GRREDGEASEPRALG 448
V G + DG P G
Sbjct: 626 RGPVGAPGLKGDGYPGVPGPRG 647
>gi|11386161 alpha 2 type IX collagen [Homo sapiens]
Length = 689
Score = 81.3 bits (199), Expect = 3e-15
Identities = 123/425 (28%), Positives = 158/425 (37%), Gaps = 67/425 (15%)
Query: 12 PGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEA 71
PGP G P V PG PG G GP G G P G GPD GP
Sbjct: 92 PGPMGIPGVKGQPG-LPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPD-GPSG 149
Query: 72 E--ARGTRGAHGETEAEEGAPE---GAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQ 126
G G G + EG+ + P G + G Q V+G + RG G+P + +
Sbjct: 150 PPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGK 209
Query: 127 REPEDSAAPERQEEAEQRPEVPEG--------SASGEAG--------DSVDAEGPLGDNI 170
P+ E+ P P+G GE G ++ A GP G+
Sbjct: 210 PGPKGDVGAS-GEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGE-- 266
Query: 171 EAEGPAGDSVEAEGRVGD--SVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGD 228
EGP G A G GD S GP G GP G A GP G ++ +
Sbjct: 267 --EGPRGPPGRA-GEKGDEGSPGIRGPQG----ITGPKG----ATGPPG--INGKDGTPG 313
Query: 229 SVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGR 288
+ +G AG + G G AG P G + G GD E GP G GP G+
Sbjct: 314 TPGMKGSAGQA-GQPGSPGHQGLAGVPGQPGTKGG--PGDQGE-PGPQG-LPGFSGPPGK 368
Query: 289 ARRVSGEPQQSGD-------GSLSPQAEAIEVAAGESAGRS--PGELAWDAAEEAE-VPG 338
GEP G+ G Q E V GR GE + +PG
Sbjct: 369 ----EGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPG 424
Query: 339 VKGSEEAAPGDARADAGEDRVGD-GPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSS 397
VKG ++ +PG +VGD G PGE E+ E GP+ ++ GE P
Sbjct: 425 VKG-DKGSPGKT---GPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYP--G 478
Query: 398 PHGEA 402
P G+A
Sbjct: 479 PSGDA 483
Score = 75.5 bits (184), Expect = 2e-13
Identities = 136/480 (28%), Positives = 182/480 (37%), Gaps = 90/480 (18%)
Query: 11 APGPQGPPEVPAPLAERPGEPGAAGGEAE-GPEGSEG-----------AEEAPRG--AAA 56
A G QG P P P R G PG AG + E GP G +G EE PRG A
Sbjct: 218 ASGEQGIPGPPGPQGIR-GYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRA 276
Query: 57 VKEAGGGGPD-RGPEAEARGTRGAHGE--TEAEEGAP-----------EGAEVPQGGEET 102
++ G P RGP+ G +GA G ++G P G G +
Sbjct: 277 GEKGDEGSPGIRGPQG-ITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGL 335
Query: 103 SGAQQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDA 162
+G G G G QGEP Q P S P ++ E R E+ G+ GD +
Sbjct: 336 AGVPGQPGTKGGPGDQGEP--GPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGE- 392
Query: 163 EGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLG-DNIQAEGPAGDSVD 221
GP+G GP G +G G+ +GP G GP G ++ + +
Sbjct: 393 RGPVGQ----PGPQG----RQGPKGE----QGPPG----IPGPQGLPGVKGDKGSPGKTG 436
Query: 222 AEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGV--EAGVPAGDSVEAEGPAGDS 279
G+VGD A P +G G+S E G GV E G P G S +A P
Sbjct: 437 PRGKVGDPGVAGLPG-----EKGEKGESGEPGPKGQQGVRGEPGYP-GPSGDAGAPGVQG 490
Query: 280 MDA-EGPAGRA--RRVSGEPQQSG-DGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEA- 334
GP G A R V G+P + G +G + ++VA + E+A A EA
Sbjct: 491 YPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVAL-KMLQEQLAEVAVSAKREAL 549
Query: 335 EVPGVKGSEEAAPGDARADAGEDRVG-DGPQQEPGEDEERRERSPEGPREEEAAGGEEES 393
G+ G PG + G GP+ PG + GP+ + GE+
Sbjct: 550 GAVGMMG-PPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKR---GEKGD 605
Query: 394 PDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAAR----VNGRREDGEASEPRALGQ 449
P GE RG H GP G R +NG+ DG+ P A G+
Sbjct: 606 P-----GEVGRG----------HPGMPGPPGIPGLPGRPGQAINGK--DGDRGSPGAPGE 648
Score = 69.7 bits (169), Expect = 8e-12
Identities = 134/498 (26%), Positives = 180/498 (36%), Gaps = 117/498 (23%)
Query: 12 PGPQGPPEVPAPLAERPGEPGAAGGEAE-GPEGSEGAEEAPRGAAAVKEAGGGGPDRGPE 70
PG +GPP P P PG PG+ G + + GP G G P+G +AG GPD P
Sbjct: 29 PGERGPPGPPGP----PGVPGSDGIDGDNGPPGKAG-PPGPKGEPG--KAGPDGPDGKPG 81
Query: 71 AEARGTRGAHGE--------TEAEEGAPEGAEVP----QGGEETSGAQQVEGASPGRGAQ 118
+ G GA GE + + G P +P G G + G RG +
Sbjct: 82 ID--GLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPK 139
Query: 119 GEPRGEAQREP-------------------EDSAAPERQEEAEQRPEVPEGSASGEAGDS 159
G+P + P D P + P +G G AG
Sbjct: 140 GDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQG-VKGHAG-- 196
Query: 160 VDAEGPLGD--NIEAEGPAGDSVEAEGRVGDSVDAEGPAGDS-----VDAEGPLGDNIQA 212
G LGD + GP GD V A G G GP G GP G+
Sbjct: 197 --KRGILGDPGHQGKPGPKGD-VGASGEQG----IPGPPGPQGIRGYPGMAGPKGET--- 246
Query: 213 EGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEA 272
GP G +G VG ++ A GP G+ G G + E GD G+ P G
Sbjct: 247 -GPHG----YKGMVG-AIGATGPPGEE-GPRGPPGRAGEKGDEGSPGIRG--PQG----I 293
Query: 273 EGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGR--SPGELAWDA 330
GP G A GP G ++G+ DG +P ++ +AG+ AG+ SPG
Sbjct: 294 TGPKG----ATGPPG----INGK-----DG--TPGTPGMKGSAGQ-AGQPGSPGHQGL-- 335
Query: 331 AEEAEVPGVKGSEEAAPGDARADAGEDRVG-DGPQQEPGEDEERRERSPEGPREEEAAGG 389
A VPG G+ + PGD + G GP + GE R E P+G ++ G
Sbjct: 336 ---AGVPGQPGT-KGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQG 391
Query: 390 E-----------------EESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARV 432
E E+ P P + G + G G A
Sbjct: 392 ERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGS-PGKTGPRGKVGDPGVAGLP 450
Query: 433 NGRREDGEASEPRALGQE 450
+ E GE+ EP GQ+
Sbjct: 451 GEKGEKGESGEPGPKGQQ 468
Score = 46.6 bits (109), Expect = 8e-05
Identities = 83/288 (28%), Positives = 106/288 (36%), Gaps = 27/288 (9%)
Query: 13 GPQGPPEVPAPLAERP--GEPGAAGGEAEGPEGSEGAE--EAPRGAAAVKEAGGGGPDRG 68
GPQG ER G+PG G +GP+G +G P+G VK G G
Sbjct: 379 GPQGIMGQKGDQGERGPVGQPGPQG--RQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTG 436
Query: 69 PEAEA--RGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQ 126
P + G G GE + E+G G P+G + G G S GA G
Sbjct: 437 PRGKVGDPGVAGLPGE-KGEKG-ESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGP 494
Query: 127 REPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRV 186
P A R V A+ + VD + AE EA G V
Sbjct: 495 PGPRGLAGNRGVPGQPGRQGVEGRDATDQ--HIVDVALKMLQEQLAEVAVSAKREALGAV 552
Query: 187 GDSVDAEGPAGDS--VDAEGPLGDNIQAEGPAG--DSVDAEGRVGDSVDAEGPAGDSVDA 242
G + GP G +GP G GP G V A G++G++ +G G+ D
Sbjct: 553 G-MMGPPGPPGPPGYPGKQGPHGH----PGPRGVPGIVGAVGQIGNT-GPKGKRGEKGD- 605
Query: 243 EGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGD--SMDAEGPAGR 288
G VG G P G+ G+P G GD S A G AGR
Sbjct: 606 PGEVGRG-HPGMPGPPGI-PGLPGRPGQAINGKDGDRGSPGAPGEAGR 651
>gi|22027593 alpha 1 type XIII collagen isoform 11 [Homo sapiens]
Length = 686
Score = 80.1 bits (196), Expect = 6e-15
Identities = 113/411 (27%), Positives = 155/411 (37%), Gaps = 44/411 (10%)
Query: 12 PGPQGPPEVPAPLAERPGEPGAAG-----GE--AEGPEGSEGAEEAPRGAAAVKEAGGGG 64
PGP GPP +P P + G+PG G GE G G GA+ AP A A + G
Sbjct: 271 PGPMGPPGLPGPPGPK-GDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGI 329
Query: 65 PDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGE 124
P E A G+ G G + + GG G + G PG + G+
Sbjct: 330 PGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPG-PPGPKGEAGVDGQ 388
Query: 125 AQREPEDSAAPERQEEAEQRPEVPEGSASGE--AGDSVDAEGPLGDNIE------AEGPA 176
+ ER EQ P+ P+GS GE G+ VD G + + ++ GP
Sbjct: 389 VGPPGQPGDKGERGAAGEQGPDGPKGS-KGEPGKGEMVDYNGNINEALQEIRTLALMGPP 447
Query: 177 G--DSVEAEGRVG-----DSVDAEGPAGDSVDAEGPLG--DNIQAEGPAGDSVDAEGRVG 227
G + G G + GP G + +GP G ++ GP G G+ G
Sbjct: 448 GLPGQIGPPGAPGIPGQKGEIGLPGPPGHDGE-KGPRGKPGDMGPPGPQG----PPGKDG 502
Query: 228 -DSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPA 286
V E S +G G++ +AG P G+ EAG E G G EGP
Sbjct: 503 PPGVKGENGHPGSPGEKGEKGETGQAGSP-GEKGEAGEKGNPGAEVPGLPG----PEGPP 557
Query: 287 GRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKG--SEE 344
G + G P G+ L A+ + GE R P L VPG G E
Sbjct: 558 G-PPGLQGVPGPKGEAGLD-GAKGEKGFQGEKGDRGPLGLP-GTPGPIGVPGPAGPKGER 614
Query: 345 AAPGDARADAGEDRVG-DGPQQEPGEDEERRERSPEGPREEEAAGGEEESP 394
+ GD G G PG+ R ER +G R + G++ +P
Sbjct: 615 GSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAP 665
Score = 58.5 bits (140), Expect = 2e-08
Identities = 112/445 (25%), Positives = 146/445 (32%), Gaps = 139/445 (31%)
Query: 12 PGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEA 71
PGP GPP PL PG PG G P G G P+G ++ G +RG
Sbjct: 253 PGPPGPPGPSGPLGH-PGLPGPMG-----PPGLPGPP-GPKGDPGIQGYHGRKGERGMPG 305
Query: 72 EA--RGTRGAHGETEA----EEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEA 125
G +GA G A E G P G + +G E + G + G +G G G
Sbjct: 306 MPGKHGAKGAPGIAVAGMKGEPGIP-GTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGG 364
Query: 126 QREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGR 185
+ EP P P G GEAG +G +G G GD E G
Sbjct: 365 RGEPGPPGLPG-----------PPGP-KGEAG----VDGQVGP----PGQPGDKGE-RGA 403
Query: 186 VGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDA------EGPAGDS 239
G+ +GP +GP G + E G+ VD G + +++ GP G
Sbjct: 404 AGE----QGP-------DGPKGS--KGEPGKGEMVDYNGNINEALQEIRTLALMGPPG-- 448
Query: 240 VDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAE-GPAGDSMDAEGPAGRARRVSGEPQQ 298
G++G G P G E G+P + E GP G D GP G G P +
Sbjct: 449 --LPGQIGPPGAPGIPGQKG-EIGLPGPPGHDGEKGPRGKPGDM-GPPGP----QGPPGK 500
Query: 299 SGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDR 358
G PGVKG E PG
Sbjct: 501 DGP-----------------------------------PGVKG-ENGHPGS--------- 515
Query: 359 VGDGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDS---------------------S 397
PGE E+ E G E+ GE+ +P +
Sbjct: 516 --------PGEKGEKGETGQAGSPGEKGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPG 567
Query: 398 PHGEASRGAAEPEAQLSNHLAEEGP 422
P GEA A+ E + GP
Sbjct: 568 PKGEAGLDGAKGEKGFQGEKGDRGP 592
Score = 55.5 bits (132), Expect = 2e-07
Identities = 131/572 (22%), Positives = 182/572 (31%), Gaps = 128/572 (22%)
Query: 13 GPQGPPEVPAP-----LAERPGEPGAAGGEAEGPEGSE---------------GAEEAPR 52
GP G P +P + R G PG AG GP G G + P
Sbjct: 125 GPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPGTRGFPGFPGPIGLDGKPG 184
Query: 53 GAAAVKEAGGGGP--DRGPEAEARGTRGAHGE---------------------------- 82
+ G GP GP+ + +G +G GE
Sbjct: 185 HPGPKGDMGLTGPPGQPGPQGQ-KGEKGQCGEYPHRLLPLLNSVRLAPPPVIKRRTFQGE 243
Query: 83 -TEAEEGAPEGAEVPQGGEETSGAQQVEG--ASPG----RGAQGEP--------RGE--- 124
++A P G P G G + G PG G +G+P +GE
Sbjct: 244 QSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLPGPPGPKGDPGIQGYHGRKGERGM 303
Query: 125 --------AQREPEDSAAPERQEE----------AEQRPEVPEGSASGEAGDSVDAEGPL 166
A+ P + A + E AE P +P G+ G+ DA +
Sbjct: 304 PGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLP--GLLGQKGEKGDAGNSI 361
Query: 167 GDNIEAEGPAG----DSVEAEGRVGDSVDAEGPAGD-----SVDAEGPLG-DNIQAEGPA 216
G GP G + E V V G GD + +GP G + E
Sbjct: 362 GGGRGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGK 421
Query: 217 GDSVDAEGRVGDSVD------AEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSV 270
G+ VD G + +++ GP G G++G G P G E G+P
Sbjct: 422 GEMVDYNGNINEALQEIRTLALMGPPG----LPGQIGPPGAPGIPGQKG-EIGLPGPPGH 476
Query: 271 EAE-GPAGDSMD-----AEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPG 324
+ E GP G D +GP G+ + + GS + E E S G G
Sbjct: 477 DGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEK-G 535
Query: 325 ELAWDAAEEAEVPGVKGSE--EAAPGDARADAGEDRVG-DGPQQEPGEDEERRERSPEG- 380
E AEVPG+ G E PG + G DG + E G E+ +R P G
Sbjct: 536 EAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGL 595
Query: 381 ---PREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRRE 437
P G + G+ A L G GE + R
Sbjct: 596 PGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGP 655
Query: 438 DGEASEPRALGQEHDITLFVKAGYDGESIGNC 469
G+ + A G + L G DG + C
Sbjct: 656 KGDKGDQGAPGLDAPCPL----GEDGLPVQGC 683
Score = 48.1 bits (113), Expect = 3e-05
Identities = 62/213 (29%), Positives = 75/213 (35%), Gaps = 43/213 (20%)
Query: 12 PGPQGPPEVPAPLAER-----PGEPGAAGGEAE-GPEGSEGAEEAPRGAAAVKEAGGGGP 65
PGPQGPP P + PG PG G + E G GS G E G G
Sbjct: 492 PGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPG------------EKGEAGE 539
Query: 66 DRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGE----- 120
P AE G G G P G QG G ++GA +G QGE
Sbjct: 540 KGNPGAEVPGLPGPEG--------PPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRG 591
Query: 121 PRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDS--VDAEGPLGD--NIEAEGPA 176
P G P P +R + +G G + GP GD N G
Sbjct: 592 PLG-LPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKK 650
Query: 177 GDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDN 209
G + G GD D P +DA PLG++
Sbjct: 651 G----SRGPKGDKGDQGAP---GLDAPCPLGED 676
>gi|22027587 alpha 1 type XIII collagen isoform 8 [Homo sapiens]
Length = 705
Score = 80.1 bits (196), Expect = 6e-15
Identities = 113/411 (27%), Positives = 155/411 (37%), Gaps = 44/411 (10%)
Query: 12 PGPQGPPEVPAPLAERPGEPGAAG-----GE--AEGPEGSEGAEEAPRGAAAVKEAGGGG 64
PGP GPP +P P + G+PG G GE G G GA+ AP A A + G
Sbjct: 290 PGPMGPPGLPGPPGPK-GDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGI 348
Query: 65 PDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGE 124
P E A G+ G G + + GG G + G PG + G+
Sbjct: 349 PGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPG-PPGPKGEAGVDGQ 407
Query: 125 AQREPEDSAAPERQEEAEQRPEVPEGSASGE--AGDSVDAEGPLGDNIE------AEGPA 176
+ ER EQ P+ P+GS GE G+ VD G + + ++ GP
Sbjct: 408 VGPPGQPGDKGERGAAGEQGPDGPKGS-KGEPGKGEMVDYNGNINEALQEIRTLALMGPP 466
Query: 177 G--DSVEAEGRVG-----DSVDAEGPAGDSVDAEGPLG--DNIQAEGPAGDSVDAEGRVG 227
G + G G + GP G + +GP G ++ GP G G+ G
Sbjct: 467 GLPGQIGPPGAPGIPGQKGEIGLPGPPGHDGE-KGPRGKPGDMGPPGPQG----PPGKDG 521
Query: 228 -DSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPA 286
V E S +G G++ +AG P G+ EAG E G G EGP
Sbjct: 522 PPGVKGENGHPGSPGEKGEKGETGQAGSP-GEKGEAGEKGNPGAEVPGLPG----PEGPP 576
Query: 287 GRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKG--SEE 344
G + G P G+ L A+ + GE R P L VPG G E
Sbjct: 577 G-PPGLQGVPGPKGEAGLD-GAKGEKGFQGEKGDRGPLGLP-GTPGPIGVPGPAGPKGER 633
Query: 345 AAPGDARADAGEDRVG-DGPQQEPGEDEERRERSPEGPREEEAAGGEEESP 394
+ GD G G PG+ R ER +G R + G++ +P
Sbjct: 634 GSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAP 684
Score = 58.5 bits (140), Expect = 2e-08
Identities = 112/445 (25%), Positives = 146/445 (32%), Gaps = 139/445 (31%)
Query: 12 PGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEA 71
PGP GPP PL PG PG G P G G P+G ++ G +RG
Sbjct: 272 PGPPGPPGPSGPLGH-PGLPGPMG-----PPGLPGPP-GPKGDPGIQGYHGRKGERGMPG 324
Query: 72 EA--RGTRGAHGETEA----EEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEA 125
G +GA G A E G P G + +G E + G + G +G G G
Sbjct: 325 MPGKHGAKGAPGIAVAGMKGEPGIP-GTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGG 383
Query: 126 QREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGR 185
+ EP P P G GEAG +G +G G GD E G
Sbjct: 384 RGEPGPPGLPG-----------PPGP-KGEAG----VDGQVGP----PGQPGDKGE-RGA 422
Query: 186 VGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDA------EGPAGDS 239
G+ +GP +GP G + E G+ VD G + +++ GP G
Sbjct: 423 AGE----QGP-------DGPKGS--KGEPGKGEMVDYNGNINEALQEIRTLALMGPPG-- 467
Query: 240 VDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAE-GPAGDSMDAEGPAGRARRVSGEPQQ 298
G++G G P G E G+P + E GP G D GP G G P +
Sbjct: 468 --LPGQIGPPGAPGIPGQKG-EIGLPGPPGHDGEKGPRGKPGDM-GPPGP----QGPPGK 519
Query: 299 SGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDR 358
G PGVKG E PG
Sbjct: 520 DGP-----------------------------------PGVKG-ENGHPGS--------- 534
Query: 359 VGDGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDS---------------------S 397
PGE E+ E G E+ GE+ +P +
Sbjct: 535 --------PGEKGEKGETGQAGSPGEKGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGVPG 586
Query: 398 PHGEASRGAAEPEAQLSNHLAEEGP 422
P GEA A+ E + GP
Sbjct: 587 PKGEAGLDGAKGEKGFQGEKGDRGP 611
Score = 48.1 bits (113), Expect = 3e-05
Identities = 62/213 (29%), Positives = 75/213 (35%), Gaps = 43/213 (20%)
Query: 12 PGPQGPPEVPAPLAER-----PGEPGAAGGEAE-GPEGSEGAEEAPRGAAAVKEAGGGGP 65
PGPQGPP P + PG PG G + E G GS G E G G
Sbjct: 511 PGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPG------------EKGEAGE 558
Query: 66 DRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGE----- 120
P AE G G G P G QG G ++GA +G QGE
Sbjct: 559 KGNPGAEVPGLPGPEG--------PPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRG 610
Query: 121 PRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDS--VDAEGPLGD--NIEAEGPA 176
P G P P +R + +G G + GP GD N G
Sbjct: 611 PLG-LPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKK 669
Query: 177 GDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDN 209
G + G GD D P +DA PLG++
Sbjct: 670 G----SRGPKGDKGDQGAP---GLDAPCPLGED 695
>gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]
Length = 540
Score = 79.7 bits (195), Expect = 8e-15
Identities = 112/410 (27%), Positives = 156/410 (38%), Gaps = 58/410 (14%)
Query: 12 PGPQGPPEVPAPLA--ERPGEPGAAGGEAE----GPEGSEGAEEAPRGAAAVKEAGGGGP 65
PG G P PL +PG PG G + GP G +G + GAA G
Sbjct: 138 PGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGDQGQD----GAAGPPGPPGPPG 193
Query: 66 DRGPEAEA--RGTRGAHGETEAE-EGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPR 122
RGP + G RGA G + E +G P+G G V G G +P
Sbjct: 194 ARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPPGPKGEPGVPGKKGDDGTPSQPG 253
Query: 123 GEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSV-- 180
+ S P + + P P+G D A GP G +G GD+V
Sbjct: 254 PPGPKGEPGSMGPRGENGVDGAPG-PKGEPGHRGTDG--AAGPRGAP-GLKGEQGDTVVI 309
Query: 181 EAEGRVGDSVDA----EGPAGDS--VDAEGPLGDNIQAEGPAGDSVDAE----GRVGDSV 230
+ +GR+ D++ +GP G A+G LG P +D E G+ GD
Sbjct: 310 DYDGRILDALKGPPGPQGPPGPPGIPGAKGELG------LPGAPGIDGEKGPKGQKGDPG 363
Query: 231 DAEGPAGDSVDAEGRVGDSVEAGDPAGDGV--EAGVPAGDSVEAEGPAGDSMDAEGPAGR 288
+ GPAG +G G+ +G P DG+ E G A DS++ + GP G
Sbjct: 364 E-PGPAG----LKGEAGEMGLSGLPGADGLKGEKGESASDSLQES--LAQLIVEPGPPG- 415
Query: 289 ARRVSGEPQQSG-DGSLSPQA-EAIEVAAGESAGRSPGELAWDAAEEAEV--PGVKGSEE 344
G P G G P+ + + G S R P L + PG KG E+
Sbjct: 416 ---PPGPPGPMGLQGIQGPKGLDGAKGEKGASGERGPSGLPGPVGPPGLIGLPGTKG-EK 471
Query: 345 AAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAAGGEEESP 394
PG+ D GP+ E G+ ER E+ G + G++ P
Sbjct: 472 GRPGEPGLDG-----FPGPRGEKGDRSERGEKGERGVPGRKGVKGQKGEP 516
Score = 42.7 bits (99), Expect = 0.001
Identities = 52/185 (28%), Positives = 69/185 (37%), Gaps = 12/185 (6%)
Query: 284 GPAGRARRVSGEPQQSG-DGSLS-PQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKG 341
GP G++ R G P G DG P + + A G+ R G+ D A P
Sbjct: 136 GPPGQSGR-DGYPGPLGLDGKPGLPGPKGEKGAPGDFGPR--GDQGQDGAAGPPGPPGPP 192
Query: 342 SEEAAPGDARADAGEDRVGD-GPQQEPGEDEERRERSPEGPREEEAAGGE--EESPDSSP 398
PGD D G GP+ EPG+D E + P GP+ E G+ ++ S P
Sbjct: 193 GARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPPGPKGEPGVPGKKGDDGTPSQP 252
Query: 399 HGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRALGQEHDITLFVK 458
+G EP + E G G R DG A A G + + V
Sbjct: 253 GPPGPKG--EPGSM--GPRGENGVDGAPGPKGEPGHRGTDGAAGPRGAPGLKGEQGDTVV 308
Query: 459 AGYDG 463
YDG
Sbjct: 309 IDYDG 313
Score = 42.4 bits (98), Expect = 0.001
Identities = 40/123 (32%), Positives = 57/123 (46%), Gaps = 26/123 (21%)
Query: 10 VAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGP 69
V PGP GPP P P+ G G +GP+G +GA + +GA+ + G GP
Sbjct: 409 VEPGPPGPPGPPGPM-------GLQG--IQGPKGLDGA-KGEKGASGERGPSGLPGPVGP 458
Query: 70 EAEARGTRGAHGETEAEEGAP-----EGAEVPQG--GEETSGAQQVEGASPGR----GAQ 118
G G G T+ E+G P +G P+G G+ + ++ E PGR G +
Sbjct: 459 P----GLIGLPG-TKGEKGRPGEPGLDGFPGPRGEKGDRSERGEKGERGVPGRKGVKGQK 513
Query: 119 GEP 121
GEP
Sbjct: 514 GEP 516
Score = 35.4 bits (80), Expect = 0.18
Identities = 28/73 (38%), Positives = 33/73 (45%), Gaps = 13/73 (17%)
Query: 7 PEGVAPGPQGPPEV---PAPLAE--RPGEPGAAGGEAEGPEGSEG-----AEEAPRGAAA 56
P G+ PGP GPP + P E RPGEPG G GP G +G E+ RG
Sbjct: 449 PSGL-PGPVGPPGLIGLPGTKGEKGRPGEPGLDG--FPGPRGEKGDRSERGEKGERGVPG 505
Query: 57 VKEAGGGGPDRGP 69
K G + GP
Sbjct: 506 RKGVKGQKGEPGP 518
>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
Length = 684
Score = 79.3 bits (194), Expect = 1e-14
Identities = 129/457 (28%), Positives = 165/457 (36%), Gaps = 82/457 (17%)
Query: 5 AEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEA-EGPEGSEGAEEAPRGAAAVKEAGGG 63
A P G+ PGP GP P +PG+PG AG G +G G + P A E G
Sbjct: 52 AGPPGL-PGPPGPKGAPG----KPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSL 106
Query: 64 GPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEG--ASPGRGAQGEP 121
GP P +G G GE G P GG G G PG P
Sbjct: 107 GPPGPPGLGGKGLPGPPGEA--------GVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGP 158
Query: 122 RGEAQREPEDSAAPERQEEAEQRPEVPEG--------SASGEAGDSVDAEGPLGDNIEAE 173
G PE + + P P G GE G+ V +G GD
Sbjct: 159 PGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGE-VGKDGEKGDP-GPP 216
Query: 174 GPAGDSVEAEGRVGDSVDAEGPAG--DSVDAEGPLGDN--IQAEGPAGDSVDAEGRVGDS 229
GPAG + SV +GP G GP GD I GP G A G+ GD
Sbjct: 217 GPAG--------LPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPG-IPGAPGKAGDR 267
Query: 230 VDA-----EGPAGD-----SVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDS 279
+ GP GD G G S E G P DG + GVP D + E +
Sbjct: 268 GERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDG-QNGVPGLDGQKGEAGRNGA 326
Query: 280 MDAEGPAGRARRVSGEPQQSGD-GSLSPQAEAIEVAAGESAGRS--PGELAWDAAEEAEV 336
+GP G + G P ++G G + A E+ +G PG+ A E E
Sbjct: 327 PGEKGPNG----LPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGD-AGMPGERGEA 381
Query: 337 PGVKGSEEA--------APGDARADAGEDRVGD----GPQQEPGEDEERRERSPEGPREE 384
G +GS A APG + +GD GPQ G+ +R GP+ +
Sbjct: 382 -GHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGD 440
Query: 385 EAAGGEEESPDS----------SPHGEA-SRGAAEPE 410
+ G + P P GE+ SRG P+
Sbjct: 441 QGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPK 477
Score = 77.8 bits (190), Expect = 3e-14
Identities = 134/468 (28%), Positives = 164/468 (35%), Gaps = 84/468 (17%)
Query: 12 PGPQGPPEVPAPLAER-----PGEPGAAGGEAE-GPEGSEGAE-----EAPRGAAAVKEA 60
PGP GPP P+ R PG PG AG E GPEG G + P+G V
Sbjct: 237 PGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGP 296
Query: 61 GG--GGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQ 118
G G P + + G G GE GAP G + P G G +G RG
Sbjct: 297 SGEPGMPGKDGQNGVPGLDGQKGEA-GRNGAP-GEKGPNGLPGLPGRAGSKGEKGERGRA 354
Query: 119 GE-----PRGEAQREPEDSAAPERQEEAEQR-------PEVPEGSASGEAGDSVDAEGPL 166
GE P GE P D+ P + EA R P+ P G A G G +G +
Sbjct: 355 GELGEAGPSGEPG-VPGDAGMPGERGEAGHRGSAGALGPQGPPG-APGVRGFQ-GQKGSM 411
Query: 167 GDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDN--IQAEGPAGDSVDAEG 224
GD GP G G VGD GP G A GP GD ++G GD +G
Sbjct: 412 GDP-GLPGPQG----LRGDVGD----RGPGG----AAGPKGDQGIAGSDGLPGD----KG 454
Query: 225 RVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEG 284
+G S GP G+S + G +G G GV+ GVP GP G
Sbjct: 455 ELGPS-GLVGPKGES-GSRGELGPKGTQGPNGTSGVQ-GVP--------GPPG------- 496
Query: 285 PAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEE 344
P G + V G P +G + P EA E E G E A P GS
Sbjct: 497 PLG-LQGVPGVPGITGKPGV-PGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSI- 553
Query: 345 AAPGDARADAGEDRVGD-------------GPQQEPGEDEERRERSPEGPREEEAAGGEE 391
PG A G GP E G+ R + G + AG +
Sbjct: 554 GRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDG 613
Query: 392 ESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDG 439
D P G + Q E GP G + + G
Sbjct: 614 PEGDQGPQGPQGVPGTSKDGQ-DGAPGEPGPPGDPGLPGAIGAQGTPG 660
Score = 62.0 bits (149), Expect = 2e-09
Identities = 85/293 (29%), Positives = 114/293 (38%), Gaps = 47/293 (16%)
Query: 11 APGPQGPPEVPAPLAERPGEPGAAGGEA-EGPEGSEG--AEEAPRGAAAVK-EAGGGGPD 66
A GPQGPP P + G+ G+ G GP+G G + P GAA K + G G D
Sbjct: 389 ALGPQGPPGAPGVRGFQ-GQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSD 447
Query: 67 RGP----EAEARGTRGAHGETEAE-EGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEP 121
P E G G GE+ + E P+G + P G TSG Q V G G QG P
Sbjct: 448 GLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNG---TSGVQGVPGPPGPLGLQGVP 504
Query: 122 RGEA----QREPEDSAAPERQEE------AEQRPEVPEGSASGEAGDSVDAEGPLGDNIE 171
P A+ +R E +EQ ++ A S+ GP G
Sbjct: 505 GVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAG---- 560
Query: 172 AEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVD 231
GP G G +G A GP G GP G+ + GP G+ D +
Sbjct: 561 PPGPPG----PPGSIGHP-GARGPPG----YRGPTGE-LGDPGPRGNQGDRGDKGAAGAG 610
Query: 232 AEGPAGD-------SVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAG 277
+GP GD V + G G+P G + G+P ++ A+G G
Sbjct: 611 LDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPG-DPGLPG--AIGAQGTPG 660
Score = 41.6 bits (96), Expect = 0.002
Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 21/112 (18%)
Query: 12 PGPQGPPEVPAPLAERP-----------GEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEA 60
PG +GPP P E G+ GAAG +GPEG +G + P+G +
Sbjct: 574 PGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQG-PQGPQGVPGTSKD 632
Query: 61 G--GGGPDRGPEAE-----ARGTRGAHG--ETEAEEGAPEGAEVPQGGEETS 103
G G + GP + A G +G G +T A +GA G + G +S
Sbjct: 633 GQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEKSGSRSS 684
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 77.8 bits (190), Expect = 3e-14
Identities = 125/420 (29%), Positives = 164/420 (39%), Gaps = 74/420 (17%)
Query: 13 GPQGPPEVPAPLAER-----------PGEPGAAGGEAEGPEGSEGA--EEAPRGAAAVKE 59
GPQGPP ER PG PG G GP G +GA E+ P+G A
Sbjct: 1060 GPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG--PPGPAGEKGAPGEKGPQGPAGRDG 1117
Query: 60 AGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQG 119
G GP A G+ G G+ + E G P G + +G + +G G GA G
Sbjct: 1118 VQGPVGLPGPAGPA-GSPGEDGD-KGEIGEP-GQKGSKGDKGENGPPGPPGLQGPVGAPG 1174
Query: 120 EPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDS 179
G+ + P Q+ E A G G GP+G GP G+
Sbjct: 1175 IAGGDGEPGPRGQQGMFGQKGDE--------GARGFPG----PPGPIGLQ-GLPGPPGE- 1220
Query: 180 VEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAG--DSVDAEGRVGDSVDA----- 232
+G GD V GP G GP G N A+GP G SV + G VG+ +
Sbjct: 1221 ---KGENGD-VGPMGPPGPP-GPRGPQGPN-GADGPQGPPGSVGSVGGVGEKGEPGEAGN 1274
Query: 233 EGPAGDS--VDAEGRVGDSVEAGDP--AGDGVEAGVPAGDSVEAE-GPAGDSMD-----A 282
GP G++ +G G+ EAG P AG G P D + GP G D
Sbjct: 1275 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1334
Query: 283 EGPAGRARRVSGEPQQSGD----GSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPG 338
GPAG+ V G+ + GD G P EA PG+ A AE G
Sbjct: 1335 PGPAGQ-DGVGGDKGEDGDPGQPGPPGPSGEA-------GPPGPPGKRGPPGAAGAE--G 1384
Query: 339 VKGSEEAAPGDARADAGEDRVG----DGPQQEPGEDEERRERSPEGPREEEAAGGEEESP 394
+G E+ A G+A A+ + G GP +PG + R P G + A G++ P
Sbjct: 1385 RQG-EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1443
Score = 75.1 bits (183), Expect = 2e-13
Identities = 135/485 (27%), Positives = 177/485 (36%), Gaps = 73/485 (15%)
Query: 7 PEGVAPGPQGPPEVPAPLAER-----PGEPGAAGGEAEGPEGSEGAEEAP-----RGAAA 56
P+G A GP G P E+ PG PG G +GP+GS G P +GA
Sbjct: 827 PKGRA-GPTGDPGPSGQAGEKGKLGVPGLPGYPG--RQGPKGSTGFPGFPGANGEKGARG 883
Query: 57 VKEAGGGGPDRGPEAEARGTRGAHGET-EAEEGAPEGAEVPQGGEETSGAQQVEGASPGR 115
V G RGP RG+RGA G T + G + P G G Q +G
Sbjct: 884 VAGKPGPRGQRGPTGP-RGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFP 942
Query: 116 GAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSAS--GEAGDSVDAEGPLGDNIEAE 173
G +G P G ++ +R E Q P G G G + + GP+G+
Sbjct: 943 GPKGPP-GPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET-GPIGERGHP- 999
Query: 174 GPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAG--------DSVDAEGR 225
GP G E +G G + EG GD GP G + + +GPAG A+G
Sbjct: 1000 GPPGPPGE-QGLPG-AAGKEGAKGDP----GPQGISGK-DGPAGLRGFPGERGLPGAQGA 1052
Query: 226 VGDSVDAEGPAGDS--VDAEGRVGDSVEAGD-----------PAGDGVEAGVPAGDSVEA 272
G EGP G V + G G + AG P G E G P
Sbjct: 1053 PGLK-GGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG--P 1109
Query: 273 EGPAGDS-----MDAEGPAGRARRVSGEPQQSGD-GSLS-PQAEAIEVAAGESAGRSPGE 325
+GPAG + GPAG A G P + GD G + P + + GE+ P
Sbjct: 1110 QGPAGRDGVQGPVGLPGPAGPA----GSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1165
Query: 326 LAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGD-GPQQEPGEDEERRERSPEGPREE 384
L PG+ G + PG + GD G + PG + GP E
Sbjct: 1166 LQGPVG----APGIAGGD-GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1220
Query: 385 EAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEP 444
+ G+ P P RG P +GP G V + E GEA P
Sbjct: 1221 KGENGDV-GPMGPPGPPGPRGPQGPNGADG----PQGPPGSVGSVGGVGEKGEPGEAGNP 1275
Query: 445 RALGQ 449
G+
Sbjct: 1276 GPPGE 1280
Score = 73.9 bits (180), Expect = 4e-13
Identities = 132/488 (27%), Positives = 178/488 (36%), Gaps = 96/488 (19%)
Query: 5 AEPEGVA--PGPQGPPEVPAPLAER--PGEPGAAGGEA--------------EGPEGSEG 46
A P G+ PG QGP P +R PG PG G + G +GS+G
Sbjct: 459 AGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG 518
Query: 47 ----AEEAPRGA----AAVKEAGGGGP----DRGPEAEARGTRGAHGET-EAEEGAPEGA 93
A+EA A A + G GP R G+ GA GE+ + P G
Sbjct: 519 PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGV 578
Query: 94 EVPQGGEETSGAQQVEGASPGRGAQGEP--RGEAQREPEDSAAPERQEEAEQRPEVPEGS 151
+ P G G + GA GRG GEP +G+ + ++ E+ P+ P G
Sbjct: 579 QGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGP 638
Query: 152 ASGEAGDSVDAE-GPLGDNIEAEGPAG-----DSVEAEGRVGDSVDAEGPAGDSVDAEGP 205
+ D E GP G EA GP G + A G+ G +GP G + GP
Sbjct: 639 PGDDGMRGEDGEIGPRGLPGEA-GPRGLLGPRGTPGAPGQPG-MAGVDGPPGPKGNM-GP 695
Query: 206 LGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVP 265
G+ GP G +G G GP +G +G E G P G AG+P
Sbjct: 696 QGE----PGPPGQ----QGNPGPQ-GLPGP-------QGPIGPPGEKG-PQGKPGLAGLP 738
Query: 266 AGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGD-GSLSPQAEAIEVAAGESAGRSPG 324
A+GP G G+ QSG+ G+L P + PG
Sbjct: 739 G---------------ADGPPGH----PGKEGQSGEKGALGPPGPQGPIG-------YPG 772
Query: 325 ELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREE 384
A+ V G+KGS+ D D G + E G+ R E PEGP+
Sbjct: 773 PRGVKGAD--GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGR 830
Query: 385 EAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAA--RVNGRR-EDGEA 441
G D P G+A L + +GP +G NG + G A
Sbjct: 831 AGPTG-----DPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 885
Query: 442 SEPRALGQ 449
+P GQ
Sbjct: 886 GKPGPRGQ 893
Score = 71.2 bits (173), Expect = 3e-12
Identities = 133/500 (26%), Positives = 173/500 (34%), Gaps = 79/500 (15%)
Query: 2 AEAAEPEGVAPGPQGPPEV---PAPLAE--RPGEPGAAGGE-------AEGPEGSEGAEE 49
+ A+ E PGPQGP V P P + + G PGA GG A+G G +G
Sbjct: 560 SSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPG 619
Query: 50 APRGAAAVKEAGGGGPDRGPEAEARGTRGAHGETEAE----EGAPEGAEVPQGGEETSGA 105
P E G GP GP + G RG GE E P G P+G T GA
Sbjct: 620 LPGDKGHRGERGPQGPP-GPPGD-DGMRGEDGEIGPRGLPGEAGPRGLLGPRG---TPGA 674
Query: 106 QQVEGASPGRGAQGEPRGEAQREPEDSAAPERQE--EAEQRPEVPEGSASGEAGDSVDAE 163
G + G G P + P+ P Q+ Q P+G +
Sbjct: 675 PGQPGMA---GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 731
Query: 164 GPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAG----DS 219
L A+GP G + EG+ G+ A GP G +GP+G GP G D
Sbjct: 732 PGLAGLPGADGPPGHPGK-EGQSGEK-GALGPPG----PQGPIG----YPGPRGVKGADG 781
Query: 220 V-DAEGRVGDSVDAEGPA--GDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPA 276
V +G G+ + P GD + +G G+ + G DG E P G + GP
Sbjct: 782 VRGLKGSKGEKGEDGFPGFKGD-MGLKGDRGEVGQIGPRGEDGPEG--PKGRA----GPT 834
Query: 277 GDSMDAEGPAGRARR--------VSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAW 328
GD GP+G+A + G P + G S A GE R
Sbjct: 835 GD----PGPSGQAGEKGKLGVPGLPGYPGRQGPKG-STGFPGFPGANGEKGARGVAGKPG 889
Query: 329 DAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAAG 388
+ G +GS A + GDGP PG ER P+GP+
Sbjct: 890 PRGQRGPT-GPRGSRGARGPTGKPGPKGTSGGDGPPGPPG------ERGPQGPQGPVGFP 942
Query: 389 GEEESP-----DSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASE 443
G + P D P RG E GP G GE
Sbjct: 943 GPKGPPGPPGKDGLPGHPGQRG----ETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGH 998
Query: 444 PRALGQEHDITLFVKAGYDG 463
P G + L AG +G
Sbjct: 999 PGPPGPPGEQGLPGAAGKEG 1018
Score = 69.3 bits (168), Expect = 1e-11
Identities = 127/491 (25%), Positives = 164/491 (33%), Gaps = 99/491 (20%)
Query: 12 PGPQGPPEVPAPLAERPGEPGAAGGEAE-------------------GPEGSEGAEEAPR 52
PG QGP G PG G E GP GS GA P
Sbjct: 858 PGRQGPKG-------STGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGA-RGPT 909
Query: 53 GAAAVKEAGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGAS 112
G K GG GP E RG +G G P+G P G + G G +
Sbjct: 910 GKPGPKGTSGGDGPPGPPGE-RGPQGPQGPVGFP--GPKGPPGPPGKDGLPGHPGQRGET 966
Query: 113 PGRGAQGEPR-----GEAQREPEDSAAPERQEEAEQRPEVPEG--SASGEAGDSVDAEGP 165
+G G P G E ER P +G A+G+ G D GP
Sbjct: 967 GFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGD-PGP 1025
Query: 166 LGDNIEAEGPAG--------DSVEAEGRVGDSVDAEGPAG-----------DSVDAEGPL 206
G + +GPAG A+G G EGP G S GP+
Sbjct: 1026 QGIS-GKDGPAGLRGFPGERGLPGAQGAPG-LKGGEGPQGPPGPVGSPGERGSAGTAGPI 1083
Query: 207 G--DNIQAEGPAGDSVDAEGRVGDSVDAEGPAG-DSVDAE-GRVGDSVEAGDPAGDGVEA 262
G +GP G + + +G G+ +GPAG D V G G + AG P DG +
Sbjct: 1084 GLPGRPGPQGPPGPAGE-KGAPGEK-GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKG 1141
Query: 263 GVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQA-EAIEVAAGESAGR 321
+ ++G G++ GP G V GDG P+ + + G+ R
Sbjct: 1142 EIGEPGQKGSKGDKGEN-GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1200
Query: 322 S----PGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERS 377
PG + +PG G E+ GD GP PG
Sbjct: 1201 GFPGPPGPIGLQG-----LPGPPG-EKGENGDV-----------GPMGPPG--------- 1234
Query: 378 PEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRRE 437
P GPR + G + P P S G + + GP +G R E
Sbjct: 1235 PPGPRGPQGPNG-ADGPQGPPGSVGSVGGVGEKGE-PGEAGNPGPPGEAGVGGPKGERGE 1292
Query: 438 DGEASEPRALG 448
GEA P A G
Sbjct: 1293 KGEAGPPGAAG 1303
Score = 68.2 bits (165), Expect = 2e-11
Identities = 106/344 (30%), Positives = 127/344 (36%), Gaps = 69/344 (20%)
Query: 7 PEGVAPGPQGPPEVPAPL-----------AERPGEPGAAGGEAEGPEGSEG--AEEAPRG 53
P G A GPQGPP + A PG PG AG GP+G G E P G
Sbjct: 1244 PNG-ADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG--VGGPKGERGEKGEAGPPG 1300
Query: 54 AAAVKEAGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASP 113
AA A G D GP+ G G G+ P G P G++ G + E P
Sbjct: 1301 AAGPPGAKGPPGDDGPKGNP-GPVGFPGDP-----GPPGEPGP-AGQDGVGGDKGEDGDP 1353
Query: 114 GRGAQGEPRGEA-QREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDN--I 170
G+ P GEA P P AE R E A GEAG AEGP G +
Sbjct: 1354 GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ--GEKGAKGEAG----AEGPPGKTGPV 1407
Query: 171 EAEGPAGDSVEAEGRVGDSVDAEGPAGD-----SVDAEGPLGDNIQAEGPAGDSVDAEGR 225
+GPAG EG G GP G+ + +GP G GP G G
Sbjct: 1408 GPQGPAG-KPGPEGLRG----IPGPVGEQGLPGAAGQDGPPG----PMGPPG----LPGL 1454
Query: 226 VGD--SVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAG------ 277
GD S +G G + G G+ E GD G + A GPAG
Sbjct: 1455 KGDPGSKGEKGHPG-LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPG 1513
Query: 278 --DSMDAEGPAGRARRVSGEPQQSGD-------GSLSPQAEAIE 312
+GP G + +G Q GD GS P E I+
Sbjct: 1514 PPGLPGPQGPKGN-KGSTGPAGQKGDSGLPGPPGSPGPPGEVIQ 1556
Score = 55.1 bits (131), Expect = 2e-07
Identities = 73/246 (29%), Positives = 98/246 (39%), Gaps = 30/246 (12%)
Query: 12 PGPQGPPEVPAPLAER--PGEPGAAGGEAE-GPEGSEGAEEAPRGAAAVKEAGGGGPDRG 68
PGP G P P +R PG GA G + E G +G GAE P V G G G
Sbjct: 1359 PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP-G 1417
Query: 69 PEAEARGTRGAHGETEAEEGAP--EGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQ 126
PE G RG G E+G P G + P G G ++G +G +G P
Sbjct: 1418 PE----GLRGIPGPV-GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL 1472
Query: 127 REPEDSAAPERQEEAEQRPEVPEGS--ASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEG 184
P E+ E+ ++ +GS A G+ G A GPLG GP G +G
Sbjct: 1473 IGPPG----EQGEKGDRGLPGTQGSPGAKGDGGIPGPA-GPLG----PPGPPG-LPGPQG 1522
Query: 185 RVGDSVDAEGPAGDSVDA--EGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDA 242
G+ + GPAG D+ GP G + GP G+ + + G DA
Sbjct: 1523 PKGNK-GSTGPAGQKGDSGLPGPPG----SPGPPGEVIQPLPILSSKKTRRHTEGMQADA 1577
Query: 243 EGRVGD 248
+ + D
Sbjct: 1578 DDNILD 1583
Score = 32.3 bits (72), Expect = 1.5
Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 12/65 (18%)
Query: 5 AEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGG 64
A+ +G PGP GP P P PG PG +GP+G++G+ P G ++G G
Sbjct: 1496 AKGDGGIPGPAGPLGPPGP----PGLPG-----PQGPKGNKGS-TGPAGQKG--DSGLPG 1543
Query: 65 PDRGP 69
P P
Sbjct: 1544 PPGSP 1548
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 77.8 bits (190), Expect = 3e-14
Identities = 125/420 (29%), Positives = 164/420 (39%), Gaps = 74/420 (17%)
Query: 13 GPQGPPEVPAPLAER-----------PGEPGAAGGEAEGPEGSEGA--EEAPRGAAAVKE 59
GPQGPP ER PG PG G GP G +GA E+ P+G A
Sbjct: 1009 GPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG--PPGPAGEKGAPGEKGPQGPAGRDG 1066
Query: 60 AGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQG 119
G GP A G+ G G+ + E G P G + +G + +G G GA G
Sbjct: 1067 VQGPVGLPGPAGPA-GSPGEDGD-KGEIGEP-GQKGSKGDKGENGPPGPPGLQGPVGAPG 1123
Query: 120 EPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDS 179
G+ + P Q+ E A G G GP+G GP G+
Sbjct: 1124 IAGGDGEPGPRGQQGMFGQKGDE--------GARGFPG----PPGPIGLQ-GLPGPPGE- 1169
Query: 180 VEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAG--DSVDAEGRVGDSVDA----- 232
+G GD V GP G GP G N A+GP G SV + G VG+ +
Sbjct: 1170 ---KGENGD-VGPMGPPGPP-GPRGPQGPN-GADGPQGPPGSVGSVGGVGEKGEPGEAGN 1223
Query: 233 EGPAGDS--VDAEGRVGDSVEAGDP--AGDGVEAGVPAGDSVEAE-GPAGDSMD-----A 282
GP G++ +G G+ EAG P AG G P D + GP G D
Sbjct: 1224 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1283
Query: 283 EGPAGRARRVSGEPQQSGD----GSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPG 338
GPAG+ V G+ + GD G P EA PG+ A AE G
Sbjct: 1284 PGPAGQ-DGVGGDKGEDGDPGQPGPPGPSGEA-------GPPGPPGKRGPPGAAGAE--G 1333
Query: 339 VKGSEEAAPGDARADAGEDRVG----DGPQQEPGEDEERRERSPEGPREEEAAGGEEESP 394
+G E+ A G+A A+ + G GP +PG + R P G + A G++ P
Sbjct: 1334 RQG-EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1392
Score = 75.1 bits (183), Expect = 2e-13
Identities = 135/485 (27%), Positives = 177/485 (36%), Gaps = 73/485 (15%)
Query: 7 PEGVAPGPQGPPEVPAPLAER-----PGEPGAAGGEAEGPEGSEGAEEAP-----RGAAA 56
P+G A GP G P E+ PG PG G +GP+GS G P +GA
Sbjct: 776 PKGRA-GPTGDPGPSGQAGEKGKLGVPGLPGYPG--RQGPKGSTGFPGFPGANGEKGARG 832
Query: 57 VKEAGGGGPDRGPEAEARGTRGAHGET-EAEEGAPEGAEVPQGGEETSGAQQVEGASPGR 115
V G RGP RG+RGA G T + G + P G G Q +G
Sbjct: 833 VAGKPGPRGQRGPTGP-RGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFP 891
Query: 116 GAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSAS--GEAGDSVDAEGPLGDNIEAE 173
G +G P G ++ +R E Q P G G G + + GP+G+
Sbjct: 892 GPKGPP-GPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET-GPIGERGHP- 948
Query: 174 GPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAG--------DSVDAEGR 225
GP G E +G G + EG GD GP G + + +GPAG A+G
Sbjct: 949 GPPGPPGE-QGLPG-AAGKEGAKGDP----GPQGISGK-DGPAGLRGFPGERGLPGAQGA 1001
Query: 226 VGDSVDAEGPAGDS--VDAEGRVGDSVEAGD-----------PAGDGVEAGVPAGDSVEA 272
G EGP G V + G G + AG P G E G P
Sbjct: 1002 PGLK-GGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG--P 1058
Query: 273 EGPAGDS-----MDAEGPAGRARRVSGEPQQSGD-GSLS-PQAEAIEVAAGESAGRSPGE 325
+GPAG + GPAG A G P + GD G + P + + GE+ P
Sbjct: 1059 QGPAGRDGVQGPVGLPGPAGPA----GSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1114
Query: 326 LAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGD-GPQQEPGEDEERRERSPEGPREE 384
L PG+ G + PG + GD G + PG + GP E
Sbjct: 1115 LQGPVG----APGIAGGD-GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1169
Query: 385 EAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEP 444
+ G+ P P RG P +GP G V + E GEA P
Sbjct: 1170 KGENGDV-GPMGPPGPPGPRGPQGPNGADG----PQGPPGSVGSVGGVGEKGEPGEAGNP 1224
Query: 445 RALGQ 449
G+
Sbjct: 1225 GPPGE 1229
Score = 73.9 bits (180), Expect = 4e-13
Identities = 132/488 (27%), Positives = 178/488 (36%), Gaps = 96/488 (19%)
Query: 5 AEPEGVA--PGPQGPPEVPAPLAER--PGEPGAAGGEA--------------EGPEGSEG 46
A P G+ PG QGP P +R PG PG G + G +GS+G
Sbjct: 408 AGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG 467
Query: 47 ----AEEAPRGA----AAVKEAGGGGP----DRGPEAEARGTRGAHGET-EAEEGAPEGA 93
A+EA A A + G GP R G+ GA GE+ + P G
Sbjct: 468 PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGV 527
Query: 94 EVPQGGEETSGAQQVEGASPGRGAQGEP--RGEAQREPEDSAAPERQEEAEQRPEVPEGS 151
+ P G G + GA GRG GEP +G+ + ++ E+ P+ P G
Sbjct: 528 QGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGP 587
Query: 152 ASGEAGDSVDAE-GPLGDNIEAEGPAG-----DSVEAEGRVGDSVDAEGPAGDSVDAEGP 205
+ D E GP G EA GP G + A G+ G +GP G + GP
Sbjct: 588 PGDDGMRGEDGEIGPRGLPGEA-GPRGLLGPRGTPGAPGQPG-MAGVDGPPGPKGNM-GP 644
Query: 206 LGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVP 265
G+ GP G +G G GP +G +G E G P G AG+P
Sbjct: 645 QGE----PGPPGQ----QGNPGPQ-GLPGP-------QGPIGPPGEKG-PQGKPGLAGLP 687
Query: 266 AGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGD-GSLSPQAEAIEVAAGESAGRSPG 324
A+GP G G+ QSG+ G+L P + PG
Sbjct: 688 G---------------ADGPPGH----PGKEGQSGEKGALGPPGPQGPIG-------YPG 721
Query: 325 ELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREE 384
A+ V G+KGS+ D D G + E G+ R E PEGP+
Sbjct: 722 PRGVKGAD--GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGR 779
Query: 385 EAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAA--RVNGRR-EDGEA 441
G D P G+A L + +GP +G NG + G A
Sbjct: 780 AGPTG-----DPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 834
Query: 442 SEPRALGQ 449
+P GQ
Sbjct: 835 GKPGPRGQ 842
Score = 71.2 bits (173), Expect = 3e-12
Identities = 133/500 (26%), Positives = 173/500 (34%), Gaps = 79/500 (15%)
Query: 2 AEAAEPEGVAPGPQGPPEV---PAPLAE--RPGEPGAAGGE-------AEGPEGSEGAEE 49
+ A+ E PGPQGP V P P + + G PGA GG A+G G +G
Sbjct: 509 SSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPG 568
Query: 50 APRGAAAVKEAGGGGPDRGPEAEARGTRGAHGETEAE----EGAPEGAEVPQGGEETSGA 105
P E G GP GP + G RG GE E P G P+G T GA
Sbjct: 569 LPGDKGHRGERGPQGPP-GPPGD-DGMRGEDGEIGPRGLPGEAGPRGLLGPRG---TPGA 623
Query: 106 QQVEGASPGRGAQGEPRGEAQREPEDSAAPERQE--EAEQRPEVPEGSASGEAGDSVDAE 163
G + G G P + P+ P Q+ Q P+G +
Sbjct: 624 PGQPGMA---GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 680
Query: 164 GPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAG----DS 219
L A+GP G + EG+ G+ A GP G +GP+G GP G D
Sbjct: 681 PGLAGLPGADGPPGHPGK-EGQSGEK-GALGPPG----PQGPIG----YPGPRGVKGADG 730
Query: 220 V-DAEGRVGDSVDAEGPA--GDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPA 276
V +G G+ + P GD + +G G+ + G DG E P G + GP
Sbjct: 731 VRGLKGSKGEKGEDGFPGFKGD-MGLKGDRGEVGQIGPRGEDGPEG--PKGRA----GPT 783
Query: 277 GDSMDAEGPAGRARR--------VSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAW 328
GD GP+G+A + G P + G S A GE R
Sbjct: 784 GD----PGPSGQAGEKGKLGVPGLPGYPGRQGPKG-STGFPGFPGANGEKGARGVAGKPG 838
Query: 329 DAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAAG 388
+ G +GS A + GDGP PG ER P+GP+
Sbjct: 839 PRGQRGPT-GPRGSRGARGPTGKPGPKGTSGGDGPPGPPG------ERGPQGPQGPVGFP 891
Query: 389 GEEESP-----DSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASE 443
G + P D P RG E GP G GE
Sbjct: 892 GPKGPPGPPGKDGLPGHPGQRG----ETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGH 947
Query: 444 PRALGQEHDITLFVKAGYDG 463
P G + L AG +G
Sbjct: 948 PGPPGPPGEQGLPGAAGKEG 967
Score = 69.3 bits (168), Expect = 1e-11
Identities = 127/491 (25%), Positives = 164/491 (33%), Gaps = 99/491 (20%)
Query: 12 PGPQGPPEVPAPLAERPGEPGAAGGEAE-------------------GPEGSEGAEEAPR 52
PG QGP G PG G E GP GS GA P
Sbjct: 807 PGRQGPKG-------STGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGA-RGPT 858
Query: 53 GAAAVKEAGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGAS 112
G K GG GP E RG +G G P+G P G + G G +
Sbjct: 859 GKPGPKGTSGGDGPPGPPGE-RGPQGPQGPVGFP--GPKGPPGPPGKDGLPGHPGQRGET 915
Query: 113 PGRGAQGEPR-----GEAQREPEDSAAPERQEEAEQRPEVPEG--SASGEAGDSVDAEGP 165
+G G P G E ER P +G A+G+ G D GP
Sbjct: 916 GFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGD-PGP 974
Query: 166 LGDNIEAEGPAG--------DSVEAEGRVGDSVDAEGPAG-----------DSVDAEGPL 206
G + +GPAG A+G G EGP G S GP+
Sbjct: 975 QGIS-GKDGPAGLRGFPGERGLPGAQGAPG-LKGGEGPQGPPGPVGSPGERGSAGTAGPI 1032
Query: 207 G--DNIQAEGPAGDSVDAEGRVGDSVDAEGPAG-DSVDAE-GRVGDSVEAGDPAGDGVEA 262
G +GP G + + +G G+ +GPAG D V G G + AG P DG +
Sbjct: 1033 GLPGRPGPQGPPGPAGE-KGAPGEK-GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKG 1090
Query: 263 GVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQA-EAIEVAAGESAGR 321
+ ++G G++ GP G V GDG P+ + + G+ R
Sbjct: 1091 EIGEPGQKGSKGDKGEN-GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1149
Query: 322 S----PGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERS 377
PG + +PG G E+ GD GP PG
Sbjct: 1150 GFPGPPGPIGLQG-----LPGPPG-EKGENGDV-----------GPMGPPG--------- 1183
Query: 378 PEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRRE 437
P GPR + G + P P S G + + GP +G R E
Sbjct: 1184 PPGPRGPQGPNG-ADGPQGPPGSVGSVGGVGEKGE-PGEAGNPGPPGEAGVGGPKGERGE 1241
Query: 438 DGEASEPRALG 448
GEA P A G
Sbjct: 1242 KGEAGPPGAAG 1252
Score = 68.2 bits (165), Expect = 2e-11
Identities = 106/344 (30%), Positives = 127/344 (36%), Gaps = 69/344 (20%)
Query: 7 PEGVAPGPQGPPEVPAPL-----------AERPGEPGAAGGEAEGPEGSEG--AEEAPRG 53
P G A GPQGPP + A PG PG AG GP+G G E P G
Sbjct: 1193 PNG-ADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG--VGGPKGERGEKGEAGPPG 1249
Query: 54 AAAVKEAGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASP 113
AA A G D GP+ G G G+ P G P G++ G + E P
Sbjct: 1250 AAGPPGAKGPPGDDGPKGNP-GPVGFPGDP-----GPPGEPGP-AGQDGVGGDKGEDGDP 1302
Query: 114 GRGAQGEPRGEA-QREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDN--I 170
G+ P GEA P P AE R E A GEAG AEGP G +
Sbjct: 1303 GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ--GEKGAKGEAG----AEGPPGKTGPV 1356
Query: 171 EAEGPAGDSVEAEGRVGDSVDAEGPAGD-----SVDAEGPLGDNIQAEGPAGDSVDAEGR 225
+GPAG EG G GP G+ + +GP G GP G G
Sbjct: 1357 GPQGPAG-KPGPEGLRG----IPGPVGEQGLPGAAGQDGPPG----PMGPPG----LPGL 1403
Query: 226 VGD--SVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAG------ 277
GD S +G G + G G+ E GD G + A GPAG
Sbjct: 1404 KGDPGSKGEKGHPG-LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPG 1462
Query: 278 --DSMDAEGPAGRARRVSGEPQQSGD-------GSLSPQAEAIE 312
+GP G + +G Q GD GS P E I+
Sbjct: 1463 PPGLPGPQGPKGN-KGSTGPAGQKGDSGLPGPPGSPGPPGEVIQ 1505
Score = 55.1 bits (131), Expect = 2e-07
Identities = 73/246 (29%), Positives = 98/246 (39%), Gaps = 30/246 (12%)
Query: 12 PGPQGPPEVPAPLAER--PGEPGAAGGEAE-GPEGSEGAEEAPRGAAAVKEAGGGGPDRG 68
PGP G P P +R PG GA G + E G +G GAE P V G G G
Sbjct: 1308 PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP-G 1366
Query: 69 PEAEARGTRGAHGETEAEEGAP--EGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQ 126
PE G RG G E+G P G + P G G ++G +G +G P
Sbjct: 1367 PE----GLRGIPGPV-GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL 1421
Query: 127 REPEDSAAPERQEEAEQRPEVPEGS--ASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEG 184
P E+ E+ ++ +GS A G+ G A GPLG GP G +G
Sbjct: 1422 IGPPG----EQGEKGDRGLPGTQGSPGAKGDGGIPGPA-GPLG----PPGPPG-LPGPQG 1471
Query: 185 RVGDSVDAEGPAGDSVDA--EGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDA 242
G+ + GPAG D+ GP G + GP G+ + + G DA
Sbjct: 1472 PKGNK-GSTGPAGQKGDSGLPGPPG----SPGPPGEVIQPLPILSSKKTRRHTEGMQADA 1526
Query: 243 EGRVGD 248
+ + D
Sbjct: 1527 DDNILD 1532
Score = 32.3 bits (72), Expect = 1.5
Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 12/65 (18%)
Query: 5 AEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGG 64
A+ +G PGP GP P P PG PG +GP+G++G+ P G ++G G
Sbjct: 1445 AKGDGGIPGPAGPLGPPGP----PGLPG-----PQGPKGNKGS-TGPAGQKG--DSGLPG 1492
Query: 65 PDRGP 69
P P
Sbjct: 1493 PPGSP 1497
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.129 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,488,754
Number of Sequences: 37866
Number of extensions: 2113126
Number of successful extensions: 24239
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 400
Number of HSP's successfully gapped in prelim test: 1663
Number of HSP's that attempted gapping in prelim test: 11050
Number of HSP's gapped (non-prelim): 8635
length of query: 686
length of database: 18,247,518
effective HSP length: 109
effective length of query: 577
effective length of database: 14,120,124
effective search space: 8147311548
effective search space used: 8147311548
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.