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Search of human proteins with 27597073
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27597073 epoxide hydrolase 2, cytoplasmic [Homo sapiens]
(555 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27597073 epoxide hydrolase 2, cytoplasmic [Homo sapiens] 1134 0.0
gi|218777837 abhydrolase domain containing 7 [Homo sapiens] 159 8e-39
gi|218777840 abhydrolase domain containing 9 [Homo sapiens] 134 2e-31
gi|13376164 abhydrolase domain containing 9 [Homo sapiens] 134 2e-31
gi|48976061 acyl-Coenzyme A dehydrogenase family, member 10 isof... 123 4e-28
gi|211971012 acyl-Coenzyme A dehydrogenase family, member 10 iso... 123 4e-28
gi|211971008 acyl-Coenzyme A dehydrogenase family, member 10 iso... 107 3e-23
gi|145611434 abhydrolase domain containing 8 [Homo sapiens] 58 3e-08
gi|23200012 abhydrolase domain containing 11 isoform 2 [Homo sap... 53 6e-07
gi|23200008 abhydrolase domain containing 11 isoform 1 [Homo sap... 53 8e-07
gi|18777795 serine hydrolase-like 2 [Homo sapiens] 49 2e-05
gi|223941839 abhydrolase domain containing 11 isoform 8 [Homo sa... 47 5e-05
gi|50658087 abhydrolase domain containing 4 [Homo sapiens] 45 1e-04
gi|31542303 abhydrolase domain containing 5 [Homo sapiens] 42 0.002
gi|29294639 mesoderm specific transcript isoform a [Homo sapiens] 42 0.002
gi|29294637 mesoderm specific transcript isoform b [Homo sapiens] 42 0.002
gi|29294635 mesoderm specific transcript isoform b [Homo sapiens] 42 0.002
gi|189027141 abhydrolase domain containing 6 [Homo sapiens] 40 0.007
gi|226443152 abhydrolase domain containing 14B [Homo sapiens] 38 0.021
gi|14249382 abhydrolase domain containing 14B [Homo sapiens] 38 0.021
gi|4503583 epoxide hydrolase 1 [Homo sapiens] 36 0.081
gi|209862837 epoxide hydrolase 1 [Homo sapiens] 36 0.081
gi|226437571 abhydrolase domain containing 14A [Homo sapiens] 34 0.31
gi|13654294 haloacid dehalogenase-like hydrolase domain containi... 34 0.31
gi|8923001 abhydrolase domain containing 10 [Homo sapiens] 34 0.40
gi|32528310 abhydrolase domain containing 12B isoform c [Homo sa... 32 1.2
gi|32451492 abhydrolase domain containing 12B isoform b [Homo sa... 32 1.2
gi|148005039 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncoge... 31 3.4
gi|4557695 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene... 31 3.4
gi|169218115 PREDICTED: similar to KIT protein [Homo sapiens] 31 3.4
>gi|27597073 epoxide hydrolase 2, cytoplasmic [Homo sapiens]
Length = 555
Score = 1134 bits (2934), Expect = 0.0
Identities = 555/555 (100%), Positives = 555/555 (100%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS
Sbjct: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 541 WLDSDARNPPVVSKM 555
>gi|218777837 abhydrolase domain containing 7 [Homo sapiens]
Length = 362
Score = 159 bits (401), Expect = 8e-39
Identities = 105/334 (31%), Positives = 170/334 (50%), Gaps = 48/334 (14%)
Query: 229 PTSC--NPSDMSHGYVTVKPR-VRLHFVELGSG--PAVCLCHGFPESWYSWRYQIPALAQ 283
P +C +PS +H YV +K +R H+V G P + L HGFPE WYSWRYQ+ +
Sbjct: 59 PPACLSDPSLGTHCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRYQLREF-K 117
Query: 284 AGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWY 343
+ YRV+A+D++GYGE+ AP + Y ++ L ++ LD LG S+ V IGHDWGGM+ W
Sbjct: 118 SEYRVVALDLRGYGETDAPIHRQNYKLDCLITDIKDILDSLGYSKCVLIGHDWGGMIAWL 177
Query: 344 MALFYPERVRAVASLNTPFIPANPNM-------SPLESIKANPVFDYQLYFQEPGVAEAE 396
+A+ YPE V + +N P +PN+ P + +K++ Y +FQ P E
Sbjct: 178 IAICYPEMVMKLIVINFP----HPNVFTEYILRHPAQLLKSS----YYYFFQIPWFPEFM 229
Query: 397 LEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKK 456
N + K LF + + K C+ +T E+++ Y+ F +
Sbjct: 230 FSINDFKVLKHLFTSHSTGI--GRKGCQ-----------------LTTEDLEAYIYVFSQ 270
Query: 457 SG-FRGPLNWYRNMERNWKWACKSL-GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHL 514
G GP+N YRN+ ++C L + P L++ E D + +M++ + ++ +
Sbjct: 271 PGALSGPINHYRNI-----FSCLPLKHHMVTTPTLLLWGENDAFMEVEMAEVTKIYVKNY 325
Query: 515 KRGHI-EDCGHWTQMDKPTEVNQILIKWLDSDAR 547
R I + HW Q D+P VN+++ +L + R
Sbjct: 326 FRLTILSEASHWLQQDQPDIVNKLIWTFLKEETR 359
>gi|218777840 abhydrolase domain containing 9 [Homo sapiens]
Length = 360
Score = 134 bits (338), Expect = 2e-31
Identities = 91/316 (28%), Positives = 155/316 (49%), Gaps = 35/316 (11%)
Query: 233 NPSDMSHGYVTVKPR-VRLHFVELG--SGPAVCLCHGFPESWYSWRYQIPALAQAGYRVL 289
+PS HG++ +K +RLH+V G +GP + HGFPE+W+SWRYQ+ Q+ + V+
Sbjct: 69 DPSLGEHGFLNLKSSGLRLHYVSAGRGNGPLMLFLHGFPENWFSWRYQLREF-QSRFHVV 127
Query: 290 AMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYP 349
A+D++GYG S AP +++ Y +++L ++ + LG S+ + + HDWG +L W+ +++YP
Sbjct: 128 AVDLRGYGPSDAPRDVDCYTIDLLLVDIKDVILGLGYSKCILVAHDWGALLAWHFSIYYP 187
Query: 350 ERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLF 409
V + ++ + + S L I Y FQ P + E L
Sbjct: 188 SLVERMVVVSGAPMSVYQDYS-LHHISQFFRSHYMFLFQLPWLPE------------KLL 234
Query: 410 RASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKK-SGFRGPLNWYRN 468
SD +L G+ P L T E++ ++ F + G GPLN+YRN
Sbjct: 235 SMSDFQILKTTLTHRKTGI-------PCL----TPSELEAFLYNFSQPGGLTGPLNYYRN 283
Query: 469 MERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHM-EDWIPHLKRGHI-EDCGHWT 526
+ RN+ +++ P L++ EKD L + + + ++P HI GHW
Sbjct: 284 LFRNFPLE----PQELTTPTLLLWGEKDTYLELGLVEAIGSRFVPGRLEAHILPGIGHWI 339
Query: 527 QMDKPTEVNQILIKWL 542
P E++Q + +L
Sbjct: 340 PQSNPQEMHQYMWAFL 355
>gi|13376164 abhydrolase domain containing 9 [Homo sapiens]
Length = 360
Score = 134 bits (338), Expect = 2e-31
Identities = 91/316 (28%), Positives = 155/316 (49%), Gaps = 35/316 (11%)
Query: 233 NPSDMSHGYVTVKPR-VRLHFVELG--SGPAVCLCHGFPESWYSWRYQIPALAQAGYRVL 289
+PS HG++ +K +RLH+V G +GP + HGFPE+W+SWRYQ+ Q+ + V+
Sbjct: 69 DPSLGEHGFLNLKSSGLRLHYVSAGRGNGPLMLFLHGFPENWFSWRYQLREF-QSRFHVV 127
Query: 290 AMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYP 349
A+D++GYG S AP +++ Y +++L ++ + LG S+ + + HDWG +L W+ +++YP
Sbjct: 128 AVDLRGYGPSDAPRDVDCYTIDLLLVDIKDVILGLGYSKCILVAHDWGALLAWHFSIYYP 187
Query: 350 ERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLF 409
V + ++ + + S L I Y FQ P + E L
Sbjct: 188 SLVERMVVVSGAPMSVYQDYS-LHHISQFFRSHYMFLFQLPWLPE------------KLL 234
Query: 410 RASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKK-SGFRGPLNWYRN 468
SD +L G+ P L T E++ ++ F + G GPLN+YRN
Sbjct: 235 SMSDFQILKTTLTHRKTGI-------PCL----TPSELEAFLYNFSQPGGLTGPLNYYRN 283
Query: 469 MERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHM-EDWIPHLKRGHI-EDCGHWT 526
+ RN+ +++ P L++ EKD L + + + ++P HI GHW
Sbjct: 284 LFRNFPLE----PQELTTPTLLLWGEKDTYLELGLVEAIGSRFVPGRLEAHILPGIGHWI 339
Query: 527 QMDKPTEVNQILIKWL 542
P E++Q + +L
Sbjct: 340 PQSNPQEMHQYMWAFL 355
>gi|48976061 acyl-Coenzyme A dehydrogenase family, member 10 isoform
b [Homo sapiens]
Length = 1059
Score = 123 bits (309), Expect = 4e-28
Identities = 81/222 (36%), Positives = 114/222 (51%), Gaps = 15/222 (6%)
Query: 2 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLS 61
T RA +FD+ GVL +P+ V E +P G + A +GG G R M+ EIT
Sbjct: 41 TYRAVIFDMGGVL-IPSPGRVAAEWEVQNRIPSGTILKALMEGGENGPWMRFMRAEITAE 99
Query: 62 QWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINR--PMLQAALMLRKKGFTT 119
++ E R CSE K +P + F S R + M +A +R KG T
Sbjct: 100 GFL---REFGRLCSEMLKTSVP----VDSFFSLLTSERVAKQFPVMTEAITQIRAKGLQT 152
Query: 120 AILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSE 179
A+L+N + + + + FD ++ESC G+ KP+P+IYK L+ L PSE
Sbjct: 153 AVLSNNFYLPNQK-----SFLPLDRKQFDVIVESCMEGICKPDPRIYKLCLEQLGLQPSE 207
Query: 180 VVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQL 221
+FLDD+G NLK A LG+ TI V D +TA+KELE + G L
Sbjct: 208 SIFLDDLGTNLKEAARLGIHTIKVNDPETAVKELEALLGFTL 249
>gi|211971012 acyl-Coenzyme A dehydrogenase family, member 10
isoform c [Homo sapiens]
Length = 890
Score = 123 bits (309), Expect = 4e-28
Identities = 81/222 (36%), Positives = 114/222 (51%), Gaps = 15/222 (6%)
Query: 2 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLS 61
T RA +FD+ GVL +P+ V E +P G + A +GG G R M+ EIT
Sbjct: 41 TYRAVIFDMGGVL-IPSPGRVAAEWEVQNRIPSGTILKALMEGGENGPWMRFMRAEITAE 99
Query: 62 QWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINR--PMLQAALMLRKKGFTT 119
++ E R CSE K +P + F S R + M +A +R KG T
Sbjct: 100 GFL---REFGRLCSEMLKTSVP----VDSFFSLLTSERVAKQFPVMTEAITQIRAKGLQT 152
Query: 120 AILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSE 179
A+L+N + + + + FD ++ESC G+ KP+P+IYK L+ L PSE
Sbjct: 153 AVLSNNFYLPNQK-----SFLPLDRKQFDVIVESCMEGICKPDPRIYKLCLEQLGLQPSE 207
Query: 180 VVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQL 221
+FLDD+G NLK A LG+ TI V D +TA+KELE + G L
Sbjct: 208 SIFLDDLGTNLKEAARLGIHTIKVNDPETAVKELEALLGFTL 249
>gi|211971008 acyl-Coenzyme A dehydrogenase family, member 10
isoform a [Homo sapiens]
Length = 1090
Score = 107 bits (267), Expect = 3e-23
Identities = 81/253 (32%), Positives = 114/253 (45%), Gaps = 46/253 (18%)
Query: 2 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLS 61
T RA +FD+ GVL +P+ V E +P G + A +GG G R M+ EIT
Sbjct: 41 TYRAVIFDMGGVL-IPSPGRVAAEWEVQNRIPSGTILKALMEGGENGPWMRFMRAEITAE 99
Query: 62 QWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINR--PMLQAALMLRKKGFTT 119
++ E R CSE K +P + F S R + M +A +R KG T
Sbjct: 100 GFL---REFGRLCSEMLKTSVP----VDSFFSLLTSERVAKQFPVMTEAITQIRAKGLQT 152
Query: 120 AILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSE 179
A+L+N + + + + FD ++ESC G+ KP+P+IYK L+ L PSE
Sbjct: 153 AVLSNNFYLPNQK-----SFLPLDRKQFDVIVESCMEGICKPDPRIYKLCLEQLGLQPSE 207
Query: 180 VVFLDDIGANLKPARDLGMVTI-------------------------------LVQDTDT 208
+FLDD+G NLK A LG+ TI V D +T
Sbjct: 208 SIFLDDLGTNLKEAARLGIHTIKRQGFAVLPKLVSNSWAQAIYPPYPPKVVRLQVNDPET 267
Query: 209 ALKELEKVTGIQL 221
A+KELE + G L
Sbjct: 268 AVKELEALLGFTL 280
>gi|145611434 abhydrolase domain containing 8 [Homo sapiens]
Length = 439
Score = 57.8 bits (138), Expect = 3e-08
Identities = 30/95 (31%), Positives = 45/95 (47%)
Query: 265 HGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKL 324
HG S W+ Q+ + GY V+A D+ G+G SSAP Y L ++M +
Sbjct: 182 HGVGGSLAIWKEQLDFFVRLGYEVVAPDLAGHGASSAPQVAAAYTFYALAEDMRAIFKRY 241
Query: 325 GLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLN 359
+ V IGH +G ++A YP+ V V +N
Sbjct: 242 AKKRNVLIGHSYGVSFCTFLAHEYPDLVHKVIMIN 276
>gi|23200012 abhydrolase domain containing 11 isoform 2 [Homo
sapiens]
Length = 308
Score = 53.1 bits (126), Expect = 6e-07
Identities = 48/171 (28%), Positives = 79/171 (46%), Gaps = 17/171 (9%)
Query: 234 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQ-AGYRVLAMD 292
PS S G +PR+ L PAV HG S ++ LAQ G RVL +D
Sbjct: 38 PSSSSGGRGGAEPRLLDGEAAL---PAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVD 94
Query: 293 MKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERV 352
+ +G+S P++ E++ +++ L +LGL V +GH GG +AL PE V
Sbjct: 95 ARNHGDSPHSPDMS---YEIMSQDLQDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPELV 151
Query: 353 RAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSR 403
+ ++ ++SP+ES + Y + +A+ EL ++ +R
Sbjct: 152 ERLIAV---------DISPVESTGVSHFATYVAAMRAINIAD-ELPRSRAR 192
>gi|23200008 abhydrolase domain containing 11 isoform 1 [Homo
sapiens]
Length = 315
Score = 52.8 bits (125), Expect = 8e-07
Identities = 49/175 (28%), Positives = 79/175 (45%), Gaps = 18/175 (10%)
Query: 234 PSDMSHGYVTVKPRVRLHFVELGSG----PAVCLCHGFPESWYSWRYQIPALAQ-AGYRV 288
PS S G +PR L G PAV HG S ++ LAQ G RV
Sbjct: 38 PSSSSGGRGGAEPRPLPLSYRLLDGEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRRV 97
Query: 289 LAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFY 348
L +D + +G+S P++ E++ +++ L +LGL V +GH GG +AL
Sbjct: 98 LTVDARNHGDSPHSPDMS---YEIMSQDLQDLLPQLGLVPCVVVGHSMGGKTAMLLALQR 154
Query: 349 PERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSR 403
PE V + ++ ++SP+ES + Y + +A+ EL ++ +R
Sbjct: 155 PELVERLIAV---------DISPVESTGVSHFATYVAAMRAINIAD-ELPRSRAR 199
>gi|18777795 serine hydrolase-like 2 [Homo sapiens]
Length = 314
Score = 48.5 bits (114), Expect = 2e-05
Identities = 48/161 (29%), Positives = 74/161 (45%), Gaps = 7/161 (4%)
Query: 258 GPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEM 317
GP V HG+ ++ S+ IP L Q Y V AMD G+G SS Y ++ E+
Sbjct: 32 GPPVLCLHGWLDNASSFDRLIPLLPQDFYYV-AMDFGGHGLSSHYSPGVPYYLQTFVSEI 90
Query: 318 VTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTP-FIPANPNMSPLESIK 376
+ L ++ +GH +GG++ +PE V + L+TP F+ + M L + K
Sbjct: 91 RRVVAALKWNRFSILGHSFGGVVGGMFFCTFPEMVDKLILLDTPLFLLESDEMENLLTYK 150
Query: 377 ANPVFDYQLYF---QEPGVAEAELEQNLSRTFKSLFRASDE 414
+ ++ L QEP L+Q L R KS S+E
Sbjct: 151 RRAI-EHVLQVEASQEPSHV-FSLKQLLQRLLKSNSHLSEE 189
>gi|223941839 abhydrolase domain containing 11 isoform 8 [Homo
sapiens]
Length = 258
Score = 47.0 bits (110), Expect = 5e-05
Identities = 37/118 (31%), Positives = 54/118 (45%), Gaps = 8/118 (6%)
Query: 234 PSDMSHGYVTVKPRVRLHFVELGSG----PAVCLCHGFPESWYSWRYQIPALAQ-AGYRV 288
PS S G +PR L G PAV HG S ++ LAQ G RV
Sbjct: 38 PSSSSGGRGGAEPRPLPLSYRLLDGEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRRV 97
Query: 289 LAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMAL 346
L +D + +G+S P++ E++ +++ L +LGL V +GH GG +AL
Sbjct: 98 LTVDARNHGDSPHSPDMS---YEIMSQDLQDLLPQLGLVPCVVVGHSMGGKTAMLLAL 152
>gi|50658087 abhydrolase domain containing 4 [Homo sapiens]
Length = 342
Score = 45.4 bits (106), Expect = 1e-04
Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 13/132 (9%)
Query: 242 VTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSA 301
VTV P E + + HGF W + +L+ A + D+ G+G SS
Sbjct: 59 VTVSP-------EQNDRTPLVMVHGFGGGVGLWILNMDSLS-ARRTLHTFDLLGFGRSSR 110
Query: 302 P--PEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLN 359
P P E + + T+ + +G+ + +GH GG L ++ YP+RV+ + ++
Sbjct: 111 PAFPRDPEGAEDEFVTSIETWRETMGIPSMILLGHSLGGFLATSYSIKYPDRVKHLILVD 170
Query: 360 T---PFIPANPN 368
P P NP+
Sbjct: 171 PWGFPLRPTNPS 182
>gi|31542303 abhydrolase domain containing 5 [Homo sapiens]
Length = 349
Score = 41.6 bits (96), Expect = 0.002
Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 11/114 (9%)
Query: 263 LCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAP------PEIEEYCMEVLCKE 316
L HGF W L V A D+ G+G SS P E+E +E
Sbjct: 80 LLHGFGGGLGLWALNFGDLC-TNRPVYAFDLLGFGRSSRPRFDSDAEEVENQFVE----S 134
Query: 317 MVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMS 370
+ + LGL + + +GH+ GG L +L YP RV + + P P+++
Sbjct: 135 IEEWRCALGLDKMILLGHNLGGFLAAAYSLKYPSRVNHLILVEPWGFPERPDLA 188
>gi|29294639 mesoderm specific transcript isoform a [Homo sapiens]
Length = 335
Score = 41.6 bits (96), Expect = 0.002
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 3/98 (3%)
Query: 255 LGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLC 314
+GS V L HGFP S Y W L +RV+A+D G+G S P Y +
Sbjct: 66 VGSPEIVVLLHGFPTSSYDWYKIWEGLTLRFHRVIALDFLGFGFSD-KPRPHHYSIFEQA 124
Query: 315 KEMVTFLDKLGLS--QAVFIGHDWGGMLVWYMALFYPE 350
+ L LGL + + HD+G ++ + Y +
Sbjct: 125 SIVEALLRHLGLQNRRINLLSHDYGDIVAQELLYRYKQ 162
>gi|29294637 mesoderm specific transcript isoform b [Homo sapiens]
Length = 326
Score = 41.6 bits (96), Expect = 0.002
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 3/98 (3%)
Query: 255 LGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLC 314
+GS V L HGFP S Y W L +RV+A+D G+G S P Y +
Sbjct: 57 VGSPEIVVLLHGFPTSSYDWYKIWEGLTLRFHRVIALDFLGFGFSD-KPRPHHYSIFEQA 115
Query: 315 KEMVTFLDKLGLS--QAVFIGHDWGGMLVWYMALFYPE 350
+ L LGL + + HD+G ++ + Y +
Sbjct: 116 SIVEALLRHLGLQNRRINLLSHDYGDIVAQELLYRYKQ 153
>gi|29294635 mesoderm specific transcript isoform b [Homo sapiens]
Length = 326
Score = 41.6 bits (96), Expect = 0.002
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 3/98 (3%)
Query: 255 LGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLC 314
+GS V L HGFP S Y W L +RV+A+D G+G S P Y +
Sbjct: 57 VGSPEIVVLLHGFPTSSYDWYKIWEGLTLRFHRVIALDFLGFGFSD-KPRPHHYSIFEQA 115
Query: 315 KEMVTFLDKLGLS--QAVFIGHDWGGMLVWYMALFYPE 350
+ L LGL + + HD+G ++ + Y +
Sbjct: 116 SIVEALLRHLGLQNRRINLLSHDYGDIVAQELLYRYKQ 153
>gi|189027141 abhydrolase domain containing 6 [Homo sapiens]
Length = 337
Score = 39.7 bits (91), Expect = 0.007
Identities = 53/295 (17%), Positives = 123/295 (41%), Gaps = 43/295 (14%)
Query: 256 GSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCK 315
G P++ + HGF W + L + ++ +DM G+ E + +++ ++ K
Sbjct: 69 GHKPSILMLHGFSAHKDMWLSVVKFLPK-NLHLVCVDMPGH-EGTTRSSLDDLSIDGQVK 126
Query: 316 EMVTFLDKLGLSQAVF--IGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLE 373
+ F++ L L++ F +G GG + A +YP V ++ + + + + ++
Sbjct: 127 RIHQFVECLKLNKKPFHLVGTSMGGQVAGVYAAYYPSDVSSLCLVCPAGLQYSTDNQFVQ 186
Query: 374 SIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSP 433
+K EL+ + + L ++ E + M ++C +V
Sbjct: 187 RLK-------------------ELQGSAAVEKIPLIPSTPEEMSEMLQLCS----YVRFK 223
Query: 434 EEPSLSRMVTEEEI---QFYVQQFKKS-GFRGPLNWYRNMERNWKWACKSLGRKILIPAL 489
+ + + + I FY + F + + + ++NM+ KI +P
Sbjct: 224 VPQQILQGLVDVRIPHNNFYRKLFLEIVSEKSRYSLHQNMD------------KIKVPTQ 271
Query: 490 MVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDS 544
++ ++D VL + + I + + +E+CGH M++P + +++I +L S
Sbjct: 272 IIWGKQDQVLDVSGADMLAKSIANCQVELLENCGHSVVMERPRKTAKLIIDFLAS 326
>gi|226443152 abhydrolase domain containing 14B [Homo sapiens]
Length = 210
Score = 38.1 bits (87), Expect = 0.021
Identities = 33/92 (35%), Positives = 43/92 (46%), Gaps = 11/92 (11%)
Query: 256 GSGPA---VCLCHGFPESWYSWRY--QIPALAQAGYRVLAMDMKGYG---ESSAPPEIEE 307
GSG A V L HG S +W+ + LAQAGYR +A+D+ G G E++AP I E
Sbjct: 27 GSGQARFSVLLLHGIRFSSETWQNLGTLHRLAQAGYRAVAIDLPGLGHSKEAAAPAPIGE 86
Query: 308 YCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGM 339
+ +D L L V I GM
Sbjct: 87 LAPGSF---LAAVVDALELGPPVVISPSLSGM 115
>gi|14249382 abhydrolase domain containing 14B [Homo sapiens]
Length = 210
Score = 38.1 bits (87), Expect = 0.021
Identities = 33/92 (35%), Positives = 43/92 (46%), Gaps = 11/92 (11%)
Query: 256 GSGPA---VCLCHGFPESWYSWRY--QIPALAQAGYRVLAMDMKGYG---ESSAPPEIEE 307
GSG A V L HG S +W+ + LAQAGYR +A+D+ G G E++AP I E
Sbjct: 27 GSGQARFSVLLLHGIRFSSETWQNLGTLHRLAQAGYRAVAIDLPGLGHSKEAAAPAPIGE 86
Query: 308 YCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGM 339
+ +D L L V I GM
Sbjct: 87 LAPGSF---LAAVVDALELGPPVVISPSLSGM 115
>gi|4503583 epoxide hydrolase 1 [Homo sapiens]
Length = 455
Score = 36.2 bits (82), Expect = 0.081
Identities = 27/113 (23%), Positives = 47/113 (41%), Gaps = 11/113 (9%)
Query: 263 LCHGFPESWYSWRYQIPALAQAG---------YRVLAMDMKGYGESSAPPEIEEYCMEVL 313
+ HG+P S+Y + IP L + V+ + GYG S A + + +
Sbjct: 146 MVHGWPGSFYEFYKIIPLLTDPKNHGLSDEHVFEVICPSIPGYGFSEASSK-KGFNSVAT 204
Query: 314 CKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN 366
+ + +LG + G DWG ++ MA P V+ + LN + +N
Sbjct: 205 ARIFYKLMLRLGFQEFYIQGGDWGSLICTNMAQLVPSHVKGL-HLNMALVLSN 256
>gi|209862837 epoxide hydrolase 1 [Homo sapiens]
Length = 455
Score = 36.2 bits (82), Expect = 0.081
Identities = 27/113 (23%), Positives = 47/113 (41%), Gaps = 11/113 (9%)
Query: 263 LCHGFPESWYSWRYQIPALAQAG---------YRVLAMDMKGYGESSAPPEIEEYCMEVL 313
+ HG+P S+Y + IP L + V+ + GYG S A + + +
Sbjct: 146 MVHGWPGSFYEFYKIIPLLTDPKNHGLSDEHVFEVICPSIPGYGFSEASSK-KGFNSVAT 204
Query: 314 CKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN 366
+ + +LG + G DWG ++ MA P V+ + LN + +N
Sbjct: 205 ARIFYKLMLRLGFQEFYIQGGDWGSLICTNMAQLVPSHVKGL-HLNMALVLSN 256
>gi|226437571 abhydrolase domain containing 14A [Homo sapiens]
Length = 271
Score = 34.3 bits (77), Expect = 0.31
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 8/66 (12%)
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRY--QIPALAQAGYRVLAMDMKGYGE 298
Y V P + H VE V L HG + ++W + L+Q GYR +A+D+ G+G
Sbjct: 83 YREVLPLNQAHRVE------VVLLHGKAFNSHTWEQLGTLQLLSQRGYRAVALDLPGFGN 136
Query: 299 SSAPPE 304
S+ E
Sbjct: 137 SAPSKE 142
>gi|13654294 haloacid dehalogenase-like hydrolase domain containing
3 [Homo sapiens]
Length = 251
Score = 34.3 bits (77), Expect = 0.31
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 16/97 (16%)
Query: 113 RKKGFTTAILTNTWLDDRAER--DGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLL 170
R +G A+++N D R E GL L+ HFDF++ S G KP+P+I++
Sbjct: 125 RTRGLRLAVISN--FDRRLEGILGGLG-----LREHFDFVLTSEAAGWPKPDPRIFQ--- 174
Query: 171 DTLKASPSEVVFLDDIGAN----LKPARDLGMVTILV 203
+ L+ + E V +G N + R +GM + LV
Sbjct: 175 EALRLAHMEPVVAAHVGDNYLCDYQGPRAVGMHSFLV 211
>gi|8923001 abhydrolase domain containing 10 [Homo sapiens]
Length = 306
Score = 33.9 bits (76), Expect = 0.40
Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Query: 285 GYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYM 344
G+ + D G G S EE + K++++ +D L + +G GG L+ +
Sbjct: 104 GHACIRFDYSGVGSSDG--NSEESTLGKWRKDVLSIIDDLADGPQILVGSSLGGWLMLHA 161
Query: 345 ALFYPERVRAVASLNT 360
A+ PE+V A+ + T
Sbjct: 162 AIARPEKVVALIGVAT 177
>gi|32528310 abhydrolase domain containing 12B isoform c [Homo
sapiens]
Length = 285
Score = 32.3 bits (72), Expect = 1.2
Identities = 16/60 (26%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Query: 278 IPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWG 337
+ L+ G+ VL++D +G+G+S+ P E + +C T + G++ GH G
Sbjct: 84 VKVLSDGGFHVLSVDYRGFGDSTGKPTEEGLTTDAICVYEWT-KARSGITPVCLWGHSLG 142
>gi|32451492 abhydrolase domain containing 12B isoform b [Homo
sapiens]
Length = 255
Score = 32.3 bits (72), Expect = 1.2
Identities = 16/60 (26%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Query: 278 IPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWG 337
+ L+ G+ VL++D +G+G+S+ P E + +C T + G++ GH G
Sbjct: 54 VKVLSDGGFHVLSVDYRGFGDSTGKPTEEGLTTDAICVYEWT-KARSGITPVCLWGHSLG 112
>gi|148005039 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene
homolog isoform 2 precursor [Homo sapiens]
Length = 972
Score = 30.8 bits (68), Expect = 3.4
Identities = 18/62 (29%), Positives = 27/62 (43%), Gaps = 1/62 (1%)
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV KP + L + L +G C+ GFPE W + + VL +D++ S
Sbjct: 408 YVNTKPEI-LTYDRLVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSG 466
Query: 301 AP 302
P
Sbjct: 467 PP 468
>gi|4557695 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene
homolog isoform 1 precursor [Homo sapiens]
Length = 976
Score = 30.8 bits (68), Expect = 3.4
Identities = 18/62 (29%), Positives = 27/62 (43%), Gaps = 1/62 (1%)
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV KP + L + L +G C+ GFPE W + + VL +D++ S
Sbjct: 408 YVNTKPEI-LTYDRLVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSG 466
Query: 301 AP 302
P
Sbjct: 467 PP 468
>gi|169218115 PREDICTED: similar to KIT protein [Homo sapiens]
Length = 245
Score = 30.8 bits (68), Expect = 3.4
Identities = 18/62 (29%), Positives = 27/62 (43%), Gaps = 1/62 (1%)
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV KP + L + L +G C+ GFPE W + + VL +D++ S
Sbjct: 91 YVNTKPEI-LTYDRLVNGMLQCVAPGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSG 149
Query: 301 AP 302
P
Sbjct: 150 PP 151
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,109,877
Number of Sequences: 37866
Number of extensions: 1006015
Number of successful extensions: 2027
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1977
Number of HSP's gapped (non-prelim): 42
length of query: 555
length of database: 18,247,518
effective HSP length: 107
effective length of query: 448
effective length of database: 14,195,856
effective search space: 6359743488
effective search space used: 6359743488
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.