Search of human proteins with 27552770

Search of human proteins with 27552770

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27552770 splA/ryanodine receptor domain and SOCS box
containing 3 [Homo sapiens]
         (355 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27552770 splA/ryanodine receptor domain and SOCS box containi...   748   0.0  
gi|18254460 splA/ryanodine receptor domain and SOCS box containi...    62   1e-09
gi|18141316 splA/ryanodine receptor domain and SOCS box containi...    61   2e-09
gi|226423903 splA/ryanodine receptor domain and SOCS box contain...    54   2e-07
gi|14249178 splA/ryanodine receptor domain and SOCS box containi...    54   2e-07
gi|157743247 F-box protein 45 [Homo sapiens]                           49   9e-06
gi|226423905 splA/ryanodine receptor domain and SOCS box contain...    45   1e-04
gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]       44   3e-04
gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens]     43   5e-04
gi|40538736 RAN binding protein 10 [Homo sapiens]                      41   0.001
gi|39812378 RAN binding protein 9 [Homo sapiens]                       41   0.002
gi|134288906 tripartite motif-containing 67 [Homo sapiens]             41   0.002
gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [H...    38   0.016
gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens]    37   0.035
gi|30410039 late cornified envelope 3A [Homo sapiens]                  33   0.39 
gi|14141161 heterogeneous nuclear ribonucleoprotein U isoform b ...    33   0.39 
gi|74136883 heterogeneous nuclear ribonucleoprotein U isoform a ...    33   0.39 
gi|46409324 SPRY domain containing 4 [Homo sapiens]                    32   0.66 
gi|41349476 PR domain containing 5 [Homo sapiens]                      32   1.1  
gi|239752834 PREDICTED: hypothetical protein [Homo sapiens]            31   1.5  
gi|239747378 PREDICTED: hypothetical protein XP_002346573 [Homo ...    31   1.5  
gi|239741203 PREDICTED: hypothetical protein XP_002342135 [Homo ...    31   1.5  
gi|13128998 sodium channel modifier 1 [Homo sapiens]                   30   2.5  
gi|13236585 fibronectin type III and SPRY domain containing 1 [H...    30   3.3  
gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens]        30   3.3  
gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens]           29   5.6  
gi|229577048 butyrophilin-like 8 isoform 6 [Homo sapiens]              29   5.6  
gi|229577043 butyrophilin-like 8 isoform 5 [Homo sapiens]              29   5.6  
gi|229577033 butyrophilin-like 8 isoform 3 precursor [Homo sapiens]    29   5.6  
gi|94957742 butyrophilin-like 8 isoform 2 precursor [Homo sapiens]     29   5.6  

>gi|27552770 splA/ryanodine receptor domain and SOCS box containing
           3 [Homo sapiens]
          Length = 355

 Score =  748 bits (1931), Expect = 0.0
 Identities = 355/355 (100%), Positives = 355/355 (100%)

Query: 1   MARRPRNSRAWHFVLSAARRDADARAVALAGSTNWGYDSDGQHSDSDSDPEYSTLPPSIP 60
           MARRPRNSRAWHFVLSAARRDADARAVALAGSTNWGYDSDGQHSDSDSDPEYSTLPPSIP
Sbjct: 1   MARRPRNSRAWHFVLSAARRDADARAVALAGSTNWGYDSDGQHSDSDSDPEYSTLPPSIP 60

Query: 61  SAVPVTGESFCDCAGQSEASFCSSLHSAHRGRDCRCGEEDEYFDWVWDDLNKSSATLLSC 120
           SAVPVTGESFCDCAGQSEASFCSSLHSAHRGRDCRCGEEDEYFDWVWDDLNKSSATLLSC
Sbjct: 61  SAVPVTGESFCDCAGQSEASFCSSLHSAHRGRDCRCGEEDEYFDWVWDDLNKSSATLLSC 120

Query: 121 DNRKVSFHMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRH 180
           DNRKVSFHMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRH
Sbjct: 121 DNRKVSFHMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRH 180

Query: 181 TFCSLLGRDEDSWGLSYTGLLHHKGDKTSFSSRFGQGSIIGVHLDTWHGTLTFFKNRKCI 240
           TFCSLLGRDEDSWGLSYTGLLHHKGDKTSFSSRFGQGSIIGVHLDTWHGTLTFFKNRKCI
Sbjct: 181 TFCSLLGRDEDSWGLSYTGLLHHKGDKTSFSSRFGQGSIIGVHLDTWHGTLTFFKNRKCI 240

Query: 241 GVAATKLQNKRFYPMVCSTAARSSMKVTRSCASATSLQYLCCHRLRQLRPDSGDTLEGLP 300
           GVAATKLQNKRFYPMVCSTAARSSMKVTRSCASATSLQYLCCHRLRQLRPDSGDTLEGLP
Sbjct: 241 GVAATKLQNKRFYPMVCSTAARSSMKVTRSCASATSLQYLCCHRLRQLRPDSGDTLEGLP 300

Query: 301 LPPGLKQVLHNKLGWVLSMSCSRRKAPVSDPQAATSAHPSSREPRPCQRKRCRRT 355
           LPPGLKQVLHNKLGWVLSMSCSRRKAPVSDPQAATSAHPSSREPRPCQRKRCRRT
Sbjct: 301 LPPGLKQVLHNKLGWVLSMSCSRRKAPVSDPQAATSAHPSSREPRPCQRKRCRRT 355


>gi|18254460 splA/ryanodine receptor domain and SOCS box containing
           4 [Homo sapiens]
          Length = 273

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 59/219 (26%), Positives = 91/219 (41%), Gaps = 20/219 (9%)

Query: 107 WDDLNKSSATLLSCDNRKVSFHMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMV 166
           W+  ++S    +  D+R        +  T  IRG      G H W+I   +   GT  +V
Sbjct: 56  WNPEDRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVV 115

Query: 167 GIGTSDVDLDKYRHTFCSLLGRDEDSWG--LSYTGLLHHKGDKTSFS--------SRFGQ 216
           G+ T+   L    +T  +L+G D +SWG  L  + L H   ++   +          F  
Sbjct: 116 GVATARAPLHSVGYT--ALVGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFLGPDEAFAL 173

Query: 217 GSIIGVHLDTWHGTLTFFKNRKCIGVAATKLQNKRFYPMVCSTAARSSMKVTRSCASATS 276
              + V LD   GTL+F  + + +GVA   L+ K+ YP+V  +A     +VT    +   
Sbjct: 174 PDSLLVVLDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVV--SAVWGHCEVTMRYINGLD 231

Query: 277 -----LQYLCCHRLRQ-LRPDSGDTLEGLPLPPGLKQVL 309
                L  LC   +R  L       +  LPLP  LK  L
Sbjct: 232 PEPLPLMDLCRRSIRSALGRQRLQDISSLPLPQSLKNYL 270


>gi|18141316 splA/ryanodine receptor domain and SOCS box containing
           1 [Homo sapiens]
          Length = 273

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 57/217 (26%), Positives = 92/217 (42%), Gaps = 16/217 (7%)

Query: 107 WDDLNKSSATLLSCDNRKVSFHMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMV 166
           W++ ++S    +  D++ +      +  T AIRG      G H W+I       GT  +V
Sbjct: 56  WNNNDRSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVV 115

Query: 167 GIGTSDVDLDKYRHTFCSLLGRDEDSWG--LSYTGLLHHKGDKTSFS--------SRFGQ 216
           G+ T+D  L    +T  +L+G + +SWG  L    L H   ++ S +          F  
Sbjct: 116 GVATADAPLHSVGYT--TLVGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIV 173

Query: 217 GSIIGVHLDTWHGTLTFFKNRKCIGVAATKLQNKRFYPMVCSTAARSSMK---VTRSCAS 273
                V LD   GTL+F  + + +GVA   L+ K+ YP+V +      ++   +      
Sbjct: 174 PDSFLVALDMDDGTLSFIVDGQYMGVAFRGLKGKKLYPVVSAVWGHCEIRMRYLNGLDPE 233

Query: 274 ATSLQYLCCHRLR-QLRPDSGDTLEGLPLPPGLKQVL 309
              L  LC   +R  L  +    +  LPLP  LK  L
Sbjct: 234 PLPLMDLCRRSVRLALGRERLGEIHTLPLPASLKAYL 270


>gi|226423903 splA/ryanodine receptor domain and SOCS box containing
           2 isoform 1 [Homo sapiens]
          Length = 263

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 53/189 (28%), Positives = 79/189 (41%), Gaps = 17/189 (8%)

Query: 135 TAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLGRDEDSWG 194
           T   RG +    G H WEI       GT  +VG+ T+   L      + +LLG + +SWG
Sbjct: 75  TDGARGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQ--TDHYAALLGSNSESWG 132

Query: 195 LSY-TGLLHH--KGDKTSFSSRFGQGSIIGVH------LDTWHGTLTFFKNRKCIGVAAT 245
                G L+H  KG          QG  + V       LD   GTL +      +G A  
Sbjct: 133 WDIGRGKLYHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGYAIGGTYLGPAFR 192

Query: 246 KLQNKRFYPMVCSTAARSSMKVTRSCASATSLQYLCCHRLRQ-LRPDSGDT----LEGLP 300
            L+ +  YP V +   +  +++ R      +  +   H  R  +R + GDT    +  LP
Sbjct: 193 GLKGRTLYPAVSAVWGQCQVRI-RYLGERRAEPHSLLHLSRLCVRHNLGDTRLGQVSALP 251

Query: 301 LPPGLKQVL 309
           LPP +K+ L
Sbjct: 252 LPPAMKRYL 260


>gi|14249178 splA/ryanodine receptor domain and SOCS box containing
           2 isoform 1 [Homo sapiens]
          Length = 263

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 53/189 (28%), Positives = 79/189 (41%), Gaps = 17/189 (8%)

Query: 135 TAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLGRDEDSWG 194
           T   RG +    G H WEI       GT  +VG+ T+   L      + +LLG + +SWG
Sbjct: 75  TDGARGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQ--TDHYAALLGSNSESWG 132

Query: 195 LSY-TGLLHH--KGDKTSFSSRFGQGSIIGVH------LDTWHGTLTFFKNRKCIGVAAT 245
                G L+H  KG          QG  + V       LD   GTL +      +G A  
Sbjct: 133 WDIGRGKLYHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGYAIGGTYLGPAFR 192

Query: 246 KLQNKRFYPMVCSTAARSSMKVTRSCASATSLQYLCCHRLRQ-LRPDSGDT----LEGLP 300
            L+ +  YP V +   +  +++ R      +  +   H  R  +R + GDT    +  LP
Sbjct: 193 GLKGRTLYPAVSAVWGQCQVRI-RYLGERRAEPHSLLHLSRLCVRHNLGDTRLGQVSALP 251

Query: 301 LPPGLKQVL 309
           LPP +K+ L
Sbjct: 252 LPPAMKRYL 260


>gi|157743247 F-box protein 45 [Homo sapiens]
          Length = 286

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 39/118 (33%), Positives = 55/118 (46%), Gaps = 10/118 (8%)

Query: 146 EGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLGRDEDSWG--LSYTGLLHH 203
           EG+H WE+    P+ GT  ++GI T    +      + +LLG D+ SWG  L    LLH+
Sbjct: 152 EGRHAWEVWWEGPL-GTVAVIGIATKRAPMQC--QGYVALLGSDDQSWGWNLVDNNLLHN 208

Query: 204 KGDKTSF-----SSRFGQGSIIGVHLDTWHGTLTFFKNRKCIGVAATKLQNKRFYPMV 256
                SF     + ++  G  I V LD    TL F +  + +GVA   L     YP V
Sbjct: 209 GEVNGSFPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKVCLYPAV 266


>gi|226423905 splA/ryanodine receptor domain and SOCS box containing
           2 isoform 2 [Homo sapiens]
          Length = 267

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 39/142 (27%), Positives = 58/142 (40%), Gaps = 11/142 (7%)

Query: 135 TAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLGRDEDSWG 194
           T   RG +    G H WEI       GT  +VG+ T+   L      + +LLG + +SWG
Sbjct: 75  TDGARGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQ--TDHYAALLGSNSESWG 132

Query: 195 LSY-TGLLHH--KGDKTSFSSRFGQGSIIGVH------LDTWHGTLTFFKNRKCIGVAAT 245
                G L+H  KG          QG  + V       LD   GTL +      +G A  
Sbjct: 133 WDIGRGKLYHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGYAIGGTYLGPAFR 192

Query: 246 KLQNKRFYPMVCSTAARSSMKV 267
            L+ +  YP V +   +  +++
Sbjct: 193 GLKGRTLYPAVSAVWGQCQVRI 214


>gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]
          Length = 710

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 39/156 (25%), Positives = 63/156 (40%), Gaps = 14/156 (8%)

Query: 105 WVWDDLNKSSATLLSCDNRKVSFHMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDM 164
           + +D  +  S  +LS DN  V+     S     + G     +G H+WE+ +       D 
Sbjct: 538 FAFDPGSAHSDIILSNDNLTVTCS---SYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDP 594

Query: 165 MVGIGTSDVDLDKYRHTFCSLLGRDEDSWGL----SYTGLLHHKGDKTSFSSRFGQGSII 220
             G+   DV  D        +LG+D+ +W +    + +  +H+            +G+ I
Sbjct: 595 AFGVARMDVMKDV-------MLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATI 647

Query: 221 GVHLDTWHGTLTFFKNRKCIGVAATKLQNKRFYPMV 256
           GV LD     LTFF N +  G  A       F+P V
Sbjct: 648 GVLLDLNRKNLTFFINDEQQGPIAFDNVEGLFFPAV 683


>gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens]
          Length = 740

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 33/119 (27%), Positives = 50/119 (42%), Gaps = 15/119 (12%)

Query: 139 RGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLGRDEDSWGLSYT 198
           R TK L +G+H++E+            VG  T    LD         LG D+  +G   T
Sbjct: 123 RATKGLMKGKHYYEVSCHDQGL---CRVGWSTMQASLD---------LGTDKFGFGFGGT 170

Query: 199 GLLHHKGDKTSFSSRFGQGSIIGVHLDTWHGTLTFFKNRKCIGVA---ATKLQNKRFYP 254
           G   H     ++   F     IG +LD   G + F KN K +G+A      ++N+  +P
Sbjct: 171 GKKSHNKQFDNYGEEFTMHDTIGCYLDIDKGHVKFSKNGKDLGLAFEIPPHMKNQALFP 229


>gi|40538736 RAN binding protein 10 [Homo sapiens]
          Length = 620

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 46/163 (28%), Positives = 72/163 (44%), Gaps = 28/163 (17%)

Query: 107 WDDLNKSSATLLSCDNRKVSF--HMEYSCGTAAIRGTKELGE--GQHFWEIKMTSPVYGT 162
           W   +K +   LS  N +V +  H +     A++R T  +    G +++E+K+ S   G 
Sbjct: 57  WSPKDKYNYIGLSQGNLRVHYKGHGKNHKDAASVRATHPIPAACGIYYFEVKIVSK--GR 114

Query: 163 DMMVGIGTSDVDLDKYRHTFCSLLGRDEDSWGLSYTGLLHHKGDKTSFSSR--------- 213
           D  +GIG S   ++  R     L G D+ S+G       +H  D  SF S          
Sbjct: 115 DGYMGIGLSAQGVNMNR-----LPGWDKHSYG-------YHGDDGHSFCSSGTGQPYGPT 162

Query: 214 FGQGSIIGVHLDTWHGTLTFFKNRKCIGVAATKLQNKRFYPMV 256
           F  G +IG  ++  +GT  + KN   +G+A T L     YP V
Sbjct: 163 FTTGDVIGCCVNLINGTCFYTKNGHSLGIAFTDLP-ANLYPTV 204


>gi|39812378 RAN binding protein 9 [Homo sapiens]
          Length = 729

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 46/163 (28%), Positives = 72/163 (44%), Gaps = 28/163 (17%)

Query: 107 WDDLNKSSATLLSCDNRKVSF--HMEYSCGTAAIRGTKELGE--GQHFWEIKMTSPVYGT 162
           W   +K S   LS +N +V +  H +     A++R T  +    G +++E+K+ S   G 
Sbjct: 169 WSPKDKFSYIGLSQNNLRVHYKGHGKTPKDAASVRATHPIPAACGIYYFEVKIVSK--GR 226

Query: 163 DMMVGIGTSDVDLDKYRHTFCSLLGRDEDSWGLSYTGLLHHKGDKTSFSSR--------- 213
           D  +GIG S   ++  R     L G D+ S+G       +H  D  SF S          
Sbjct: 227 DGYMGIGLSAQGVNMNR-----LPGWDKHSYG-------YHGDDGHSFCSSGTGQPYGPT 274

Query: 214 FGQGSIIGVHLDTWHGTLTFFKNRKCIGVAATKLQNKRFYPMV 256
           F  G +IG  ++  + T  + KN   +G+A T L     YP V
Sbjct: 275 FTTGDVIGCCVNLINNTCFYTKNGHSLGIAFTDLP-PNLYPTV 316


>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
          Length = 783

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 35/142 (24%), Positives = 58/142 (40%), Gaps = 14/142 (9%)

Query: 117 LLSCDNRKVSFHMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLD 176
           +LS DN+  +     S     + GT    +G H+WE+ +       D   G+  + V  D
Sbjct: 622 ILSNDNQTATCS---SYDDRVVLGTAAFSKGVHYWELHVDRYDNHPDPAFGVARASVVKD 678

Query: 177 KYRHTFCSLLGRDEDSWGL----SYTGLLHHKGDKTSFSSRFGQGSIIGVHLDTWHGTLT 232
                   +LG+D+ +W +    + +  +H             +G+ +GV LD    TLT
Sbjct: 679 M-------MLGKDDKAWAMYVDNNRSWFMHCNSHTNRTEGGVCKGATVGVLLDLNKHTLT 731

Query: 233 FFKNRKCIGVAATKLQNKRFYP 254
           FF N +  G  A    +  F P
Sbjct: 732 FFINGQQQGPTAFSHVDGVFMP 753


>gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [Homo
           sapiens]
          Length = 747

 Score = 37.7 bits (86), Expect = 0.016
 Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 2/60 (3%)

Query: 186 LGRDEDSWGLSYTGLLHHKGDKTSFSSRFGQGSIIG--VHLDTWHGTLTFFKNRKCIGVA 243
           LG DE S+G    GL    G    F   FG+  +IG   + +T    L+F KN + +GVA
Sbjct: 327 LGEDEFSYGFDGRGLKAENGQFEEFGQTFGENDVIGCFANFETEEVELSFSKNGEDLGVA 386


>gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens]
          Length = 4861

 Score = 36.6 bits (83), Expect = 0.035
 Identities = 23/72 (31%), Positives = 35/72 (48%)

Query: 196  SYTGLLHHKGDKTSFSSRFGQGSIIGVHLDTWHGTLTFFKNRKCIGVAATKLQNKRFYPM 255
            +Y+G L+H G++T   S F QG  I   LD    T++F KN +   +A   +     YP 
Sbjct: 2113 AYSGNLYHNGEQTLTLSSFTQGDFITCVLDMEARTISFGKNGEEPKLAFEDVDAAELYPC 2172

Query: 256  VCSTAARSSMKV 267
            V   ++    KV
Sbjct: 2173 VMFYSSNPGEKV 2184


>gi|30410039 late cornified envelope 3A [Homo sapiens]
          Length = 89

 Score = 33.1 bits (74), Expect = 0.39
 Identities = 17/42 (40%), Positives = 19/42 (45%), Gaps = 4/42 (9%)

Query: 55 LPPSIPSAVPVTGESFCDCAGQSEASFCSSLHSAHRGRDCRC 96
          LPP+  S  P +G     C   SE S C S H   R   CRC
Sbjct: 25 LPPASSSCAPSSG----GCGPSSERSCCLSHHRCRRSHRCRC 62


>gi|14141161 heterogeneous nuclear ribonucleoprotein U isoform b
           [Homo sapiens]
          Length = 806

 Score = 33.1 bits (74), Expect = 0.39
 Identities = 40/158 (25%), Positives = 73/158 (46%), Gaps = 16/158 (10%)

Query: 98  EEDEYFDWVWDDLNKSSATL---LSCDNRKVS-FHME-YSCGTAAIRGTKELGEGQHFWE 152
           EEDE+FD     L+  +  L   +S D    S   ME ++   A  R +  + +G+  +E
Sbjct: 259 EEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFE 318

Query: 153 IKMTSPVYGTDMMVGIGTSDVDLDKYR-----HTFCSLLGRDEDSWGLSYTGLLHHKGDK 207
           +K+T  +    +     T D+D+ + R      T   LLG +E S+G S  G+     + 
Sbjct: 319 MKVTEKIPVRHLY----TKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCET 374

Query: 208 TSFSSRFGQGSIIG--VHLDTWHGTLTFFKNRKCIGVA 243
             +  +F +  +I    + ++    L++ KN + +GVA
Sbjct: 375 EDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGVA 412


>gi|74136883 heterogeneous nuclear ribonucleoprotein U isoform a
           [Homo sapiens]
          Length = 825

 Score = 33.1 bits (74), Expect = 0.39
 Identities = 40/158 (25%), Positives = 73/158 (46%), Gaps = 16/158 (10%)

Query: 98  EEDEYFDWVWDDLNKSSATL---LSCDNRKVS-FHME-YSCGTAAIRGTKELGEGQHFWE 152
           EEDE+FD     L+  +  L   +S D    S   ME ++   A  R +  + +G+  +E
Sbjct: 278 EEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFE 337

Query: 153 IKMTSPVYGTDMMVGIGTSDVDLDKYR-----HTFCSLLGRDEDSWGLSYTGLLHHKGDK 207
           +K+T  +    +     T D+D+ + R      T   LLG +E S+G S  G+     + 
Sbjct: 338 MKVTEKIPVRHLY----TKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCET 393

Query: 208 TSFSSRFGQGSIIG--VHLDTWHGTLTFFKNRKCIGVA 243
             +  +F +  +I    + ++    L++ KN + +GVA
Sbjct: 394 EDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGVA 431


>gi|46409324 SPRY domain containing 4 [Homo sapiens]
          Length = 207

 Score = 32.3 bits (72), Expect = 0.66
 Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 10/81 (12%)

Query: 117 LLSCDNRKVSFHMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLD 176
           L+  +  KV+ ++E     A +     +  G+H+WE+ +            IG +DVD+ 
Sbjct: 56  LVGLEPTKVALNVERFREWAVVLADTAVTSGRHYWEVTVK-----RSQQFRIGVADVDMS 110

Query: 177 KYRHTFCSLLGRDEDSWGLSY 197
           +      S +G D+ SW  +Y
Sbjct: 111 R-----DSCIGVDDRSWVFTY 126


>gi|41349476 PR domain containing 5 [Homo sapiens]
          Length = 630

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 33/145 (22%), Positives = 58/145 (40%), Gaps = 12/145 (8%)

Query: 146 EGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLL--GRDEDSWGLSYTGLLHH 203
           EG++ + + +      T++++G   SD++ ++      +++  G  E+S   S  G    
Sbjct: 101 EGENIFYLAVEDIETDTELLIGYLDSDMEAEEEEQQIMTVIKEGEVENSRRQSTAGRKDR 160

Query: 204 KGDKTSFS-----SRFGQGSIIGVHLDTWHGTLTFFKNRKCIGVAATKLQNKRFYPMVCS 258
            G K  ++     S F    I+  HL T H   T  K  KC          +     V  
Sbjct: 161 LGCKEDYACPQCESSFTSEDILAEHLQTLHQKPTEEKEFKCKNCGKKFPVKQALQRHVLQ 220

Query: 259 TAARSSMKVTRSCASATSLQYLCCH 283
             A+SS+K      S+ S Q   C+
Sbjct: 221 CTAKSSLK-----ESSRSFQCSVCN 240


>gi|239752834 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 181

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 24/97 (24%), Positives = 37/97 (38%), Gaps = 7/97 (7%)

Query: 260 AARSSMKVTRSCASATSLQY-------LCCHRLRQLRPDSGDTLEGLPLPPGLKQVLHNK 312
           A RS+   + SC +A  L++         C  LR+ R +SG        PP L       
Sbjct: 66  AQRSAAASSGSCCAAAKLRHPDPLGTLTSCRELRESRRESGRGARAADCPPSLAGKRKVP 125

Query: 313 LGWVLSMSCSRRKAPVSDPQAATSAHPSSREPRPCQR 349
           LG   ++    +  P   P  A +   + R P+   R
Sbjct: 126 LGVPETLDYPHQADPAHSPSLAHTRAGTGRTPQQSAR 162


>gi|239747378 PREDICTED: hypothetical protein XP_002346573 [Homo
           sapiens]
          Length = 181

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 24/97 (24%), Positives = 37/97 (38%), Gaps = 7/97 (7%)

Query: 260 AARSSMKVTRSCASATSLQY-------LCCHRLRQLRPDSGDTLEGLPLPPGLKQVLHNK 312
           A RS+   + SC +A  L++         C  LR+ R +SG        PP L       
Sbjct: 66  AQRSAAASSGSCCAAAKLRHPDPLGTLTSCRELRESRRESGRGARAADCPPSLAGKRKVP 125

Query: 313 LGWVLSMSCSRRKAPVSDPQAATSAHPSSREPRPCQR 349
           LG   ++    +  P   P  A +   + R P+   R
Sbjct: 126 LGVPETLDYPHQADPAHSPSLAHTRAGTGRTPQQSAR 162


>gi|239741203 PREDICTED: hypothetical protein XP_002342135 [Homo
           sapiens]
          Length = 181

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 24/97 (24%), Positives = 37/97 (38%), Gaps = 7/97 (7%)

Query: 260 AARSSMKVTRSCASATSLQY-------LCCHRLRQLRPDSGDTLEGLPLPPGLKQVLHNK 312
           A RS+   + SC +A  L++         C  LR+ R +SG        PP L       
Sbjct: 66  AQRSAAASSGSCCAAAKLRHPDPLGTLTSCRELRESRRESGRGARAADCPPSLAGKRKVP 125

Query: 313 LGWVLSMSCSRRKAPVSDPQAATSAHPSSREPRPCQR 349
           LG   ++    +  P   P  A +   + R P+   R
Sbjct: 126 LGVPETLDYPHQADPAHSPSLAHTRAGTGRTPQQSAR 162


>gi|13128998 sodium channel modifier 1 [Homo sapiens]
          Length = 230

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 11/86 (12%)

Query: 267 VTRSCASATSLQYLCCHRLRQLRPDS-GDTLEGLPLPPGLKQVLHNKLGWVLSMSCSRRK 325
           +T+S          CC R  + RP++ G ++   P+PP   ++   K+        SR  
Sbjct: 113 ITQSALHRAPHYNSCCRR--KYRPEAPGPSVSLSPMPPSEVKLQSGKI--------SREP 162

Query: 326 APVSDPQAATSAHPSSREPRPCQRKR 351
            P + PQA  SA  S+  P    R+R
Sbjct: 163 EPAAGPQAEESATVSAPAPMSPTRRR 188


>gi|13236585 fibronectin type III and SPRY domain containing 1 [Homo
           sapiens]
          Length = 496

 Score = 30.0 bits (66), Expect = 3.3
 Identities = 26/117 (22%), Positives = 47/117 (40%), Gaps = 25/117 (21%)

Query: 131 YSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMV-GIGTSDVDLDKYRHTFCSLLGRD 189
           ++  +  + G   +  G+H+WE++     Y  D    G+G +   L ++       LG+ 
Sbjct: 338 FTAESYTVLGDTLIDGGEHYWEVR-----YEPDSKAFGVGVAYRSLGRFEQ-----LGKT 387

Query: 190 EDSWGLSYTGLLHHKGDKTSFSSRFGQG---------SIIGVHLDTWHGTLTFFKNR 237
             SW L     L     + SF+++               +GVH D   G L+F+  R
Sbjct: 388 AASWCLHVNNWL-----QVSFTAKHANKVKVLDAPVPDCLGVHCDFHQGLLSFYNAR 439


>gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens]
          Length = 882

 Score = 30.0 bits (66), Expect = 3.3
 Identities = 17/56 (30%), Positives = 30/56 (53%), Gaps = 2/56 (3%)

Query: 290 PDSGDTLEGLPLPPGLKQVLHNKLGWVLSMSCSRRKA-PVSDPQAATSAHPSSREP 344
           P   + + G PL  G+   +H   G + S++ + R A P++ PQ A + HP++  P
Sbjct: 533 PPRNNVVGGSPLAKGITTTMHPGSGSLSSLATATRPALPITTPQ-AHAQHPTASPP 587


>gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens]
          Length = 432

 Score = 29.3 bits (64), Expect = 5.6
 Identities = 28/112 (25%), Positives = 50/112 (44%), Gaps = 21/112 (18%)

Query: 131 YSC---GTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLG 187
           +SC    T+ +  ++ L  G+H+WE+   +    +   VG+ + ++  D+       +LG
Sbjct: 292 WSCERFSTSQVLCSQALSSGKHYWEVDTRN---CSHWAVGVASWEMSRDQ-------VLG 341

Query: 188 RDEDS----W-GLSYTGLLHHKGDKTSFSSRFGQGSIIGVHLDTWHGTLTFF 234
           R  DS    W G S     H   +    S R G   ++G+ L+   G L F+
Sbjct: 342 RTMDSCCVEWKGTSQLSAWHMVKETVLGSDRPG---VVGIWLNLEEGKLAFY 390


>gi|229577048 butyrophilin-like 8 isoform 6 [Homo sapiens]
          Length = 316

 Score = 29.3 bits (64), Expect = 5.6
 Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 9/109 (8%)

Query: 128 HMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLG 187
           H E      ++  ++    G+H+WE+      +     VG+   DVD  K   T    L 
Sbjct: 136 HSEKRFTRKSVVASQSFQAGKHYWEV---DGGHNKRWRVGVCRDDVDRRKEYVT----LS 188

Query: 188 RDEDSWGLSYTGLLHHKGDKTSFSSRFGQG--SIIGVHLDTWHGTLTFF 234
            D   W L   G   +      F S F +   + IGV LD   GT++FF
Sbjct: 189 PDHGYWVLRLNGEHLYFTLNPRFISVFPRTPPTKIGVFLDYECGTISFF 237


>gi|229577043 butyrophilin-like 8 isoform 5 [Homo sapiens]
          Length = 375

 Score = 29.3 bits (64), Expect = 5.6
 Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 9/109 (8%)

Query: 128 HMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLG 187
           H E      ++  ++    G+H+WE+      +     VG+   DVD  K   T    L 
Sbjct: 195 HSEKRFTRKSVVASQSFQAGKHYWEV---DGGHNKRWRVGVCRDDVDRRKEYVT----LS 247

Query: 188 RDEDSWGLSYTGLLHHKGDKTSFSSRFGQG--SIIGVHLDTWHGTLTFF 234
            D   W L   G   +      F S F +   + IGV LD   GT++FF
Sbjct: 248 PDHGYWVLRLNGEHLYFTLNPRFISVFPRTPPTKIGVFLDYECGTISFF 296


>gi|229577033 butyrophilin-like 8 isoform 3 precursor [Homo sapiens]
          Length = 384

 Score = 29.3 bits (64), Expect = 5.6
 Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 9/109 (8%)

Query: 128 HMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLG 187
           H E      ++  ++    G+H+WE+      +     VG+   DVD  K   T    L 
Sbjct: 204 HSEKRFTRKSVVASQSFQAGKHYWEV---DGGHNKRWRVGVCRDDVDRRKEYVT----LS 256

Query: 188 RDEDSWGLSYTGLLHHKGDKTSFSSRFGQG--SIIGVHLDTWHGTLTFF 234
            D   W L   G   +      F S F +   + IGV LD   GT++FF
Sbjct: 257 PDHGYWVLRLNGEHLYFTLNPRFISVFPRTPPTKIGVFLDYECGTISFF 305


>gi|94957742 butyrophilin-like 8 isoform 2 precursor [Homo sapiens]
          Length = 500

 Score = 29.3 bits (64), Expect = 5.6
 Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 9/109 (8%)

Query: 128 HMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLG 187
           H E      ++  ++    G+H+WE+      +     VG+   DVD  K   T    L 
Sbjct: 320 HSEKRFTRKSVVASQSFQAGKHYWEV---DGGHNKRWRVGVCRDDVDRRKEYVT----LS 372

Query: 188 RDEDSWGLSYTGLLHHKGDKTSFSSRFGQG--SIIGVHLDTWHGTLTFF 234
            D   W L   G   +      F S F +   + IGV LD   GT++FF
Sbjct: 373 PDHGYWVLRLNGEHLYFTLNPRFISVFPRTPPTKIGVFLDYECGTISFF 421


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.132    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,953,395
Number of Sequences: 37866
Number of extensions: 698167
Number of successful extensions: 2212
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 2186
Number of HSP's gapped (non-prelim): 40
length of query: 355
length of database: 18,247,518
effective HSP length: 103
effective length of query: 252
effective length of database: 14,347,320
effective search space: 3615524640
effective search space used: 3615524640
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.