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Search of human proteins with 27436933
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens]
(289 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens] 589 e-169
gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens] 582 e-166
gi|20070107 orthodenticle homeobox 1 [Homo sapiens] 334 6e-92
gi|4557489 cone-rod homeobox protein [Homo sapiens] 266 2e-71
gi|61969666 arginine-fifty homeobox [Homo sapiens] 101 7e-22
gi|46249382 paired-like homeobox 2a [Homo sapiens] 100 1e-21
gi|122937484 dorsal root ganglia homeobox [Homo sapiens] 96 5e-20
gi|12707580 paired-like homeobox 2b [Homo sapiens] 95 6e-20
gi|189083681 paired box gene 6 isoform a [Homo sapiens] 93 3e-19
gi|4580424 paired box gene 6 isoform b [Homo sapiens] 93 3e-19
gi|4505615 paired box gene 6 isoform a [Homo sapiens] 93 3e-19
gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Hom... 92 4e-19
gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Hom... 92 5e-19
gi|152963644 paired-like homeodomain transcription factor 1 [Hom... 91 9e-19
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 91 2e-18
gi|6031203 short stature homeobox isoform SHOXb [Homo sapiens] 90 2e-18
gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens] 90 2e-18
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 90 2e-18
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 90 2e-18
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 90 2e-18
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] 90 2e-18
gi|89145413 short stature homeobox 2 isoform a [Homo sapiens] 89 4e-18
gi|87044888 short stature homeobox 2 isoform b [Homo sapiens] 89 4e-18
gi|7706659 paired related homeobox 2 [Homo sapiens] 89 6e-18
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 88 1e-17
gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens] 88 1e-17
gi|14149760 orthopedia homeobox [Homo sapiens] 88 1e-17
gi|57232759 intestine-specific homeobox [Homo sapiens] 87 2e-17
gi|126116581 retina and anterior neural fold homeobox [Homo sapi... 86 3e-17
gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapi... 86 3e-17
>gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens]
Length = 289
Score = 589 bits (1519), Expect = e-169
Identities = 289/289 (100%), Positives = 289/289 (100%)
Query: 1 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKT 60
MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKT
Sbjct: 1 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKT 60
Query: 61 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPARE 120
RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPARE
Sbjct: 61 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPARE 120
Query: 121 VSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYT 180
VSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYT
Sbjct: 121 VSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYT 180
Query: 181 QASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLNQSPASLST 240
QASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLNQSPASLST
Sbjct: 181 QASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLNQSPASLST 240
Query: 241 QGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL 289
QGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL
Sbjct: 241 QGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL 289
>gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens]
Length = 297
Score = 582 bits (1500), Expect = e-166
Identities = 289/297 (97%), Positives = 289/297 (97%), Gaps = 8/297 (2%)
Query: 1 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYP--------ATPRKQRRERTTFTRAQLDV 52
MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYP ATPRKQRRERTTFTRAQLDV
Sbjct: 1 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV 60
Query: 53 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK 112
LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK
Sbjct: 61 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK 120
Query: 113 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ 172
KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ
Sbjct: 121 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ 180
Query: 173 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN 232
RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN
Sbjct: 181 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN 240
Query: 233 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL 289
QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL
Sbjct: 241 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL 297
>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
Length = 354
Score = 334 bits (856), Expect = 6e-92
Identities = 208/363 (57%), Positives = 230/363 (63%), Gaps = 83/363 (22%)
Query: 1 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKT 60
MMSYLKQPPY +NGL L MDLLHPSVGYPATPRKQRRERTTFTR+QLDVLEALFAKT
Sbjct: 1 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKT 60
Query: 61 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPARE 120
RYPDIFMREEVALKINLPESRVQVWFKNRRAKCR QQQQ+G K RPAKKK+SP RE
Sbjct: 61 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCR---QQQQSGSGTKSRPAKKKSSPVRE 117
Query: 121 VSSESGTSGQFTPP---SSTSVPTIASSS--------------------------APVSI 151
SS S +SGQFTPP SS S + ASSS A SI
Sbjct: 118 -SSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSI 176
Query: 152 WSPASISPLSDPLSTS----------SSCMQR-----------SYPMTYTQASGYSQGY- 189
WSPASISP S P S S +SCMQR SYPM+Y Q Y QGY
Sbjct: 177 WSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSYGQGYP 236
Query: 190 AGSTSYFGGMDCGSYLTPMH-HQLPGPGATLSPMGTNAVTSHLNQSPAS---LST----- 240
S+SYFGG+DC SYL PMH H P LSPM +++ H + P + LS
Sbjct: 237 TPSSSYFGGVDCSSYLAPMHSHHHP---HQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHH 293
Query: 241 --------QGYGASSLGFNSTTDCLDYKD-----QTASWKLNFNA-DCLDYKDQTSSWKF 286
QGYG S L FNS DCLDYK+ +++WKLNFN+ DCLDYKDQ +SW+F
Sbjct: 294 HHHHHHHHQGYGGSGLAFNS-ADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQ-ASWRF 351
Query: 287 QVL 289
QVL
Sbjct: 352 QVL 354
>gi|4557489 cone-rod homeobox protein [Homo sapiens]
Length = 299
Score = 266 bits (680), Expect = 2e-71
Identities = 158/309 (51%), Positives = 197/309 (63%), Gaps = 30/309 (9%)
Query: 1 MMSYLKQPP-YAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAK 59
MM+Y+ P Y+VN L+L+ +DL+H +V YP+ PRKQRRERTTFTR+QL+ LEALFAK
Sbjct: 1 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAK 60
Query: 60 TRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ-----QQQQQNGGQNKVRPAKKK 114
T+YPD++ REEVALKINLPESRVQVWFKNRRAKCRQQ QQQQ GGQ K RPAK+K
Sbjct: 61 TQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRK 120
Query: 115 TSPAREVSSE-----SGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDP-----L 164
+ S++ G S ++PP + ++ A VSIWSPAS SPL + +
Sbjct: 121 AGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLV 180
Query: 165 STSSSCMQRSYPMTYTQASGY---SQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSP 221
++ S Y MTY AS + Y +SYF G+D YL+PM QL GP LSP
Sbjct: 181 ASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLD--PYLSPMVPQLGGP--ALSP 236
Query: 222 MGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFN-ADCLDYKDQ 280
+ +V L QSP SLS Q YGA S D L++KD T +WK +N D LDYKDQ
Sbjct: 237 LSGPSVGPSLAQSPTSLSGQSYGA-----YSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQ 291
Query: 281 TSSWKFQVL 289
S+WKFQ+L
Sbjct: 292 -SAWKFQIL 299
>gi|61969666 arginine-fifty homeobox [Homo sapiens]
Length = 315
Score = 101 bits (252), Expect = 7e-22
Identities = 82/252 (32%), Positives = 127/252 (50%), Gaps = 30/252 (11%)
Query: 36 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
R++ +ERT+FT Q + LEALF++T +PD ++E++AL+++LPES V+VWF+NRR K ++
Sbjct: 76 RRRHKERTSFTHQQYEELEALFSQTMFPDRNLQEKLALRLDLPESTVKVWFRNRRFKLKK 135
Query: 96 QQQQQQNGGQNKVRPAKKK--TSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWS 153
QQQQQ +N++ P+KK TSP S + F+P S ++ S S W+
Sbjct: 136 QQQQQSAKQRNQILPSKKNVPTSPRTSPSPYA-----FSPVISDFYSSLPSQPLDPSNWA 190
Query: 154 PASISPLSDPLSTSSSCMQ--------RSYPMTYTQASG-------YSQGYAGSTSYFGG 198
S S STS MQ S P Y+ A Y+ S
Sbjct: 191 WNSTFTES---STSDFQMQDTQWERLVASVPALYSDAYDIFQIIELYNLPDENEISSSSF 247
Query: 199 MDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLD 258
YL+P +Q+ G G++LS AV Q+ ++++Q + A SL TD L+
Sbjct: 248 HCLYQYLSPTKYQVGGQGSSLSIFAGPAVGLSPAQTWPNMTSQAFEAYSL-----TDSLE 302
Query: 259 YKDQTASWKLNF 270
++ + L F
Sbjct: 303 FQKTSNMVDLGF 314
>gi|46249382 paired-like homeobox 2a [Homo sapiens]
Length = 284
Score = 100 bits (250), Expect = 1e-21
Identities = 74/183 (40%), Positives = 92/183 (50%), Gaps = 28/183 (15%)
Query: 8 PPYAVNGLSLTTSGMDLLHPSVGYPATP-------------RKQRRERTTFTRAQLDVLE 54
PP G S G H Y A P RKQRR RTTFT AQL LE
Sbjct: 47 PPCPALGSSNCALGALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELE 106
Query: 55 ALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKK- 113
+FA+T YPDI+ REE+ALKI+L E+RVQVWF+NRRAK R+Q++ G AKK
Sbjct: 107 RVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGAAGAKKG 166
Query: 114 --KTSPAREVSSESGTSGQFTPPSSTSV----------PTIASSSAPVSIWSPASISPLS 161
+ S + S ES S TP S+ S+ P ++ S PV++ S P
Sbjct: 167 EARCSSEDDDSKESTCSP--TPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGP 224
Query: 162 DPL 164
PL
Sbjct: 225 QPL 227
>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
Length = 268
Score = 95.5 bits (236), Expect = 5e-20
Identities = 48/89 (53%), Positives = 63/89 (70%), Gaps = 1/89 (1%)
Query: 36 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
RKQRR RTTFT QL+ LEA+FA+T YPD+F REE+A+KINL E+RVQVWF+NRRAK R+
Sbjct: 36 RKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRK 95
Query: 96 QQQQQQNGGQNKVRPAKKKT-SPAREVSS 123
++ + P + T P R ++S
Sbjct: 96 TERGASDQEPGAKEPMAEVTPPPVRNINS 124
>gi|12707580 paired-like homeobox 2b [Homo sapiens]
Length = 314
Score = 95.1 bits (235), Expect = 6e-20
Identities = 55/106 (51%), Positives = 70/106 (66%), Gaps = 4/106 (3%)
Query: 36 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
RKQRR RTTFT AQL LE +FA+T YPDI+ REE+ALKI+L E+RVQVWF+NRRAK R+
Sbjct: 96 RKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRK 155
Query: 96 QQQ-QQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVP 140
Q++ K + KK+ +R+ S+ S T P ST P
Sbjct: 156 QERAAAAAAAAAKNGSSGKKSDSSRDDESKEAKS---TDPDSTGGP 198
>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 92.8 bits (229), Expect = 3e-19
Identities = 62/186 (33%), Positives = 91/186 (48%), Gaps = 27/186 (14%)
Query: 36 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
RK +R RT+FT+ Q++ LE F +T YPD+F RE +A KI+LPE+R+QVWF NRRAK R+
Sbjct: 208 RKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRR 267
Query: 96 QQQQQQNGGQNKVRPAKKKTS-----------PAREVSSESGTSGQFTPPSSTSVPTIAS 144
+++ + Q P+ S P S TSG + T++ S
Sbjct: 268 EEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYS 327
Query: 145 SSAPVSIWSPASISPLSDP-----------LSTSSSCMQRSY-----PMTYTQASGYSQG 188
+ P+ ++ A+ P+ P L TS S RSY P T + G
Sbjct: 328 ALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMG 387
Query: 189 YAGSTS 194
+G+TS
Sbjct: 388 TSGTTS 393
>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
Length = 436
Score = 92.8 bits (229), Expect = 3e-19
Identities = 62/186 (33%), Positives = 91/186 (48%), Gaps = 27/186 (14%)
Query: 36 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
RK +R RT+FT+ Q++ LE F +T YPD+F RE +A KI+LPE+R+QVWF NRRAK R+
Sbjct: 222 RKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRR 281
Query: 96 QQQQQQNGGQNKVRPAKKKTS-----------PAREVSSESGTSGQFTPPSSTSVPTIAS 144
+++ + Q P+ S P S TSG + T++ S
Sbjct: 282 EEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYS 341
Query: 145 SSAPVSIWSPASISPLSDP-----------LSTSSSCMQRSY-----PMTYTQASGYSQG 188
+ P+ ++ A+ P+ P L TS S RSY P T + G
Sbjct: 342 ALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMG 401
Query: 189 YAGSTS 194
+G+TS
Sbjct: 402 TSGTTS 407
>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 92.8 bits (229), Expect = 3e-19
Identities = 62/186 (33%), Positives = 91/186 (48%), Gaps = 27/186 (14%)
Query: 36 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
RK +R RT+FT+ Q++ LE F +T YPD+F RE +A KI+LPE+R+QVWF NRRAK R+
Sbjct: 208 RKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRR 267
Query: 96 QQQQQQNGGQNKVRPAKKKTS-----------PAREVSSESGTSGQFTPPSSTSVPTIAS 144
+++ + Q P+ S P S TSG + T++ S
Sbjct: 268 EEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYS 327
Query: 145 SSAPVSIWSPASISPLSDP-----------LSTSSSCMQRSY-----PMTYTQASGYSQG 188
+ P+ ++ A+ P+ P L TS S RSY P T + G
Sbjct: 328 ALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMG 387
Query: 189 YAGSTS 194
+G+TS
Sbjct: 388 TSGTTS 393
>gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Homo
sapiens]
Length = 377
Score = 92.4 bits (228), Expect = 4e-19
Identities = 62/166 (37%), Positives = 82/166 (49%), Gaps = 17/166 (10%)
Query: 11 AVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREE 70
+V+ L+L D++ + Y + RKQRR RT FT QL+ LE F KT YPD+ MRE
Sbjct: 40 SVHALTLAERLADIILEA-RYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRER 98
Query: 71 VALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQ 130
+A+ NLPE+RVQVWFKNRRAK R++Q+ Q K++ +E G
Sbjct: 99 LAMCTNLPEARVQVWFKNRRAKFRKKQRSLQ----------KEQLQKQKEAEGSHGEGKA 148
Query: 131 FTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQRSYP 176
P T + T P + P S P LS S S P
Sbjct: 149 EAPTPDTQLDT----EQPPRL--PGSDPPAELHLSLSEQSASESAP 188
>gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Homo
sapiens]
Length = 382
Score = 92.0 bits (227), Expect = 5e-19
Identities = 58/146 (39%), Positives = 72/146 (49%), Gaps = 16/146 (10%)
Query: 31 YPATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRR 90
Y + RKQRR RT FT QL+ LE F KT YPD+ MRE +A+ NLPE+RVQVWFKNRR
Sbjct: 64 YGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRR 123
Query: 91 AKCRQQQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVS 150
AK R++Q+ Q K++ +E G P T + T P
Sbjct: 124 AKFRKKQRSLQ----------KEQLQKQKEAEGSHGEGKAEAPTPDTQLDT----EQPPR 169
Query: 151 IWSPASISPLSDPLSTSSSCMQRSYP 176
+ P S P LS S S P
Sbjct: 170 L--PGSDPPAELHLSLSEQSASESAP 193
>gi|152963644 paired-like homeodomain transcription factor 1 [Homo
sapiens]
Length = 314
Score = 91.3 bits (225), Expect = 9e-19
Identities = 63/148 (42%), Positives = 83/148 (56%), Gaps = 16/148 (10%)
Query: 32 PATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRA 91
PA +KQRR+RT FT QL LEA F + RYPD+ MREE+A+ NL E RV+VWFKNRRA
Sbjct: 83 PAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRA 142
Query: 92 KCRQQQQQQQ----NGGQNKVRPAKKKTSPAREV-----SSESGTSGQFTP-PSSTSVPT 141
K R++++ QQ GG V P +V S + + P P ST T
Sbjct: 143 KWRKRERNQQLDLCKGGY--VPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFT 200
Query: 142 IASSSAPVSIWS----PASISPLSDPLS 165
+S +P+S S P+SIS ++ P S
Sbjct: 201 FFNSMSPLSSQSMFSAPSSISSMTMPSS 228
>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
Length = 407
Score = 90.5 bits (223), Expect = 2e-18
Identities = 77/226 (34%), Positives = 105/226 (46%), Gaps = 45/226 (19%)
Query: 36 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
RKQRR RTTFT QL+ LE F +T YPDI+ REE+A + L E+RVQVWF NRRA+ R+
Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRK 276
Query: 96 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 155
Q Q N + P G F P T++PT+ + + + P
Sbjct: 277 QAGANQLMAFNHLIP------------------GGFPP---TAMPTLPTYQLSETSYQPT 315
Query: 156 SI-SPLSDPLST--------SSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLT 206
SI +SDP ST S+ Q + P +S Y ST + S++
Sbjct: 316 SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYC---LPSTRHGFSSYTDSFVP 372
Query: 207 PMHHQLPGPGATLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNS 252
P GP ++P N ++ Q P +S+Q SLGF S
Sbjct: 373 P-----SGPSNPMNPTIGNGLSP---QVPFIISSQ----ISLGFKS 406
>gi|6031203 short stature homeobox isoform SHOXb [Homo sapiens]
Length = 225
Score = 90.1 bits (222), Expect = 2e-18
Identities = 42/70 (60%), Positives = 52/70 (74%)
Query: 34 TPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKC 93
T KQRR RT FT QL+ LE LF +T YPD FMREE++ ++ L E+RVQVWF+NRRAKC
Sbjct: 113 TKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKC 172
Query: 94 RQQQQQQQNG 103
R+Q+ Q G
Sbjct: 173 RKQENQMHKG 182
>gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens]
Length = 292
Score = 90.1 bits (222), Expect = 2e-18
Identities = 42/70 (60%), Positives = 52/70 (74%)
Query: 34 TPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKC 93
T KQRR RT FT QL+ LE LF +T YPD FMREE++ ++ L E+RVQVWF+NRRAKC
Sbjct: 113 TKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKC 172
Query: 94 RQQQQQQQNG 103
R+Q+ Q G
Sbjct: 173 RKQENQMHKG 182
>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
Length = 483
Score = 90.1 bits (222), Expect = 2e-18
Identities = 72/209 (34%), Positives = 97/209 (46%), Gaps = 40/209 (19%)
Query: 36 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
RKQRR RTTFT QL+ LE F +T YPDI+ REE+A + L E+RVQVWF NRRA+ R+
Sbjct: 216 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRK 275
Query: 96 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 155
Q Q N + P G F P T++PT+ + + + P
Sbjct: 276 QAGANQLMAFNHLIP------------------GGFPP---TAMPTLPTYQLSETSYQPT 314
Query: 156 SI-SPLSDPLST--------SSSCMQRSYPMTYTQASGY-----SQGYAGSTSYFGGMDC 201
SI +SDP ST S+ Q + P +S Y G++ T F +
Sbjct: 315 SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSF--VPP 372
Query: 202 GSYLTPMHHQLPGPGATLSPMGTNAVTSH 230
PM+ P G LSP +T+H
Sbjct: 373 SGPSNPMN---PTIGNGLSPQVMGLLTNH 398
>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
Length = 505
Score = 90.1 bits (222), Expect = 2e-18
Identities = 72/209 (34%), Positives = 97/209 (46%), Gaps = 40/209 (19%)
Query: 36 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
RKQRR RTTFT QL+ LE F +T YPDI+ REE+A + L E+RVQVWF NRRA+ R+
Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRK 276
Query: 96 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 155
Q Q N + P G F P T++PT+ + + + P
Sbjct: 277 QAGANQLMAFNHLIP------------------GGFPP---TAMPTLPTYQLSETSYQPT 315
Query: 156 SI-SPLSDPLST--------SSSCMQRSYPMTYTQASGY-----SQGYAGSTSYFGGMDC 201
SI +SDP ST S+ Q + P +S Y G++ T F +
Sbjct: 316 SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSF--VPP 373
Query: 202 GSYLTPMHHQLPGPGATLSPMGTNAVTSH 230
PM+ P G LSP +T+H
Sbjct: 374 SGPSNPMN---PTIGNGLSPQVMGLLTNH 399
>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
Length = 484
Score = 90.1 bits (222), Expect = 2e-18
Identities = 72/209 (34%), Positives = 97/209 (46%), Gaps = 40/209 (19%)
Query: 36 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
RKQRR RTTFT QL+ LE F +T YPDI+ REE+A + L E+RVQVWF NRRA+ R+
Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRK 276
Query: 96 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 155
Q Q N + P G F P T++PT+ + + + P
Sbjct: 277 QAGANQLMAFNHLIP------------------GGFPP---TAMPTLPTYQLSETSYQPT 315
Query: 156 SI-SPLSDPLST--------SSSCMQRSYPMTYTQASGY-----SQGYAGSTSYFGGMDC 201
SI +SDP ST S+ Q + P +S Y G++ T F +
Sbjct: 316 SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSF--VPP 373
Query: 202 GSYLTPMHHQLPGPGATLSPMGTNAVTSH 230
PM+ P G LSP +T+H
Sbjct: 374 SGPSNPMN---PTIGNGLSPQVMGLLTNH 399
>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
Length = 479
Score = 90.1 bits (222), Expect = 2e-18
Identities = 72/209 (34%), Positives = 97/209 (46%), Gaps = 40/209 (19%)
Query: 36 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
RKQRR RTTFT QL+ LE F +T YPDI+ REE+A + L E+RVQVWF NRRA+ R+
Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRK 276
Query: 96 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 155
Q Q N + P G F P T++PT+ + + + P
Sbjct: 277 QAGANQLMAFNHLIP------------------GGFPP---TAMPTLPTYQLSETSYQPT 315
Query: 156 SI-SPLSDPLST--------SSSCMQRSYPMTYTQASGY-----SQGYAGSTSYFGGMDC 201
SI +SDP ST S+ Q + P +S Y G++ T F +
Sbjct: 316 SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSF--VPP 373
Query: 202 GSYLTPMHHQLPGPGATLSPMGTNAVTSH 230
PM+ P G LSP +T+H
Sbjct: 374 SGPSNPMN---PTIGNGLSPQVMGLLTNH 399
>gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]
Length = 331
Score = 89.0 bits (219), Expect = 4e-18
Identities = 42/70 (60%), Positives = 52/70 (74%)
Query: 34 TPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKC 93
T KQRR RT FT QL+ LE LF +T YPD FMREE++ ++ L E+RVQVWF+NRRAKC
Sbjct: 136 TKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKC 195
Query: 94 RQQQQQQQNG 103
R+Q+ Q G
Sbjct: 196 RKQENQLHKG 205
>gi|87044888 short stature homeobox 2 isoform b [Homo sapiens]
Length = 190
Score = 89.0 bits (219), Expect = 4e-18
Identities = 42/70 (60%), Positives = 52/70 (74%)
Query: 34 TPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKC 93
T KQRR RT FT QL+ LE LF +T YPD FMREE++ ++ L E+RVQVWF+NRRAKC
Sbjct: 7 TKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKC 66
Query: 94 RQQQQQQQNG 103
R+Q+ Q G
Sbjct: 67 RKQENQLHKG 76
>gi|7706659 paired related homeobox 2 [Homo sapiens]
Length = 253
Score = 88.6 bits (218), Expect = 6e-18
Identities = 51/139 (36%), Positives = 76/139 (54%), Gaps = 14/139 (10%)
Query: 36 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
+KQRR RTTF +QL LE +F +T YPD F+REE+A ++NL E+RVQVWF+NRRAK R+
Sbjct: 102 KKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRR 161
Query: 96 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVP-----TIASSSAPVS 150
+ + A + S + S E+ P + P T +S + V
Sbjct: 162 NE---------RAMLASRSASLLKSYSQEAAIEQPVAPRPTALSPDYLSWTASSPYSTVP 212
Query: 151 IWSPASISPLSDPLSTSSS 169
+SP S P + ++ ++S
Sbjct: 213 PYSPGSSGPATPGVNMANS 231
>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
Length = 403
Score = 87.8 bits (216), Expect = 1e-17
Identities = 71/212 (33%), Positives = 99/212 (46%), Gaps = 40/212 (18%)
Query: 36 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
RKQRR RTTFT QL+ LE F +T YPDI+ REE+A + L E+RVQVWF NRRA+ R+
Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRK 276
Query: 96 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 155
Q Q N + P G F P T++PT+ + + + P
Sbjct: 277 QAGANQLMAFNHLIP------------------GGFPP---TAMPTLPTYQLSETSYQPT 315
Query: 156 SI-SPLSDPLST--------SSSCMQRSYPMTYTQASGY-----SQGYAGSTSYFGGMDC 201
SI +SDP ST S+ Q + P +S Y G++ T F +
Sbjct: 316 SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSF--VPP 373
Query: 202 GSYLTPMHHQLPGPGATLSPMGTNAVTSHLNQ 233
PM+ P G LSP ++S +++
Sbjct: 374 SGPSNPMN---PTIGNGLSPQVPFIISSQISR 402
>gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]
Length = 325
Score = 87.8 bits (216), Expect = 1e-17
Identities = 42/63 (66%), Positives = 53/63 (84%)
Query: 36 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
+KQ+R RT FT AQL+ LE FAKT YPDIFMREE+AL+I L ESRVQVWF+NRRAK ++
Sbjct: 102 QKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKK 161
Query: 96 QQQ 98
+++
Sbjct: 162 RKK 164
>gi|14149760 orthopedia homeobox [Homo sapiens]
Length = 325
Score = 87.8 bits (216), Expect = 1e-17
Identities = 42/63 (66%), Positives = 53/63 (84%)
Query: 36 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
+KQ+R RT FT AQL+ LE FAKT YPDIFMREE+AL+I L ESRVQVWF+NRRAK ++
Sbjct: 102 QKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKK 161
Query: 96 QQQ 98
+++
Sbjct: 162 RKK 164
>gi|57232759 intestine-specific homeobox [Homo sapiens]
Length = 245
Score = 86.7 bits (213), Expect = 2e-17
Identities = 57/145 (39%), Positives = 80/145 (55%), Gaps = 7/145 (4%)
Query: 20 SGMDLLHPSVGYPATPRK-QRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLP 78
SG L P P RK +RR RTTFT QL LE +F T YPD+ +R ++A +INLP
Sbjct: 63 SGSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLP 122
Query: 79 ESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPAREVSSESGTS---GQFTPPS 135
E+RVQ+WF+N+RAK R+Q++ G ++ A +V+ + TS + PP+
Sbjct: 123 EARVQIWFQNQRAKWRKQEKIGNLGAPQQLSEASVALPTNLDVAGPTWTSTALRRLAPPT 182
Query: 136 STSVPTIASSSAPVSIWSPASISPL 160
S P+ A S W PA I+ L
Sbjct: 183 S-CCPSAQDQLA--SAWFPAWITLL 204
>gi|126116581 retina and anterior neural fold homeobox [Homo
sapiens]
Length = 346
Score = 86.3 bits (212), Expect = 3e-17
Identities = 54/128 (42%), Positives = 68/128 (53%), Gaps = 29/128 (22%)
Query: 27 PSVGYPATP--------------RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVA 72
PS G P P +K RR RTTFT QL LE F K+ YPD++ REE+A
Sbjct: 111 PSPGLPVGPATGEAKLSEEEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELA 170
Query: 73 LKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFT 132
K+NLPE RVQVWF+NRRAK R+Q++ + V K + SP S +
Sbjct: 171 GKVNLPEVRVQVWFQNRRAKWRRQEKLE-------VSSMKLQDSPLLSFSR--------S 215
Query: 133 PPSSTSVP 140
PPS+T P
Sbjct: 216 PPSATLSP 223
>gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo
sapiens]
Length = 245
Score = 86.3 bits (212), Expect = 3e-17
Identities = 54/139 (38%), Positives = 71/139 (51%), Gaps = 17/139 (12%)
Query: 36 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 95
RKQRR RTTF +QL LE +F +T YPD F+RE++A ++NL E+RVQVWF+NRRAK R+
Sbjct: 92 RKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRR 151
Query: 96 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 155
+ + A K S + SG T VP A W A
Sbjct: 152 NE---------RAMLANKNASLLKSY------SGDVTAVEQPIVPRPAPRPTDYLSWGTA 196
Query: 156 SISPLSDPLSTSSSCMQRS 174
SP S + S++C S
Sbjct: 197 --SPYSAMATYSATCANNS 213
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.125 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,294,275
Number of Sequences: 37866
Number of extensions: 592098
Number of successful extensions: 4224
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 311
Number of HSP's successfully gapped in prelim test: 231
Number of HSP's that attempted gapping in prelim test: 3137
Number of HSP's gapped (non-prelim): 1106
length of query: 289
length of database: 18,247,518
effective HSP length: 101
effective length of query: 188
effective length of database: 14,423,052
effective search space: 2711533776
effective search space used: 2711533776
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.