Guide to the Human Genome
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Search of human proteins with 12229217

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|12229217 activity-dependent neuroprotector [Homo sapiens]
         (1102 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31563503 activity-dependent neuroprotector [Homo sapiens]         2257   0.0  
gi|12229217 activity-dependent neuroprotector [Homo sapiens]         2257   0.0  
gi|7662346 ADNP homeobox 2 [Homo sapiens]                             249   8e-66
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    55   5e-07
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu...    48   4e-05
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre...    48   4e-05
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    47   8e-05
gi|114431236 zinc finger protein 462 [Homo sapiens]                    47   1e-04
gi|157676340 zinc finger protein 142 [Homo sapiens]                    46   2e-04
gi|169213065 PREDICTED: similar to hCG1654128 [Homo sapiens]           46   2e-04
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    45   5e-04
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    45   5e-04
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]      44   6e-04
gi|169213233 PREDICTED: similar to hCG1654128 [Homo sapiens]           44   6e-04
gi|169212742 PREDICTED: similar to hCG1654128 [Homo sapiens]           42   0.002
gi|109452595 zinc finger protein 205 [Homo sapiens]                    42   0.002
gi|109452593 zinc finger protein 205 [Homo sapiens]                    42   0.002
gi|197382841 zinc finger protein 485 [Homo sapiens]                    41   0.005
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           41   0.005
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    41   0.007
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    41   0.007
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    41   0.007
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo...    41   0.007
gi|24415404 MDN1, midasin homolog [Homo sapiens]                       41   0.007
gi|61743930 zinc finger and BTB domain containing 41 [Homo sapiens]    40   0.009
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           40   0.009
gi|16445033 ACRC protein [Homo sapiens]                                40   0.012
gi|40806227 zinc finger protein 64 isoform c [Homo sapiens]            40   0.016
gi|40806225 zinc finger protein 64 isoform b [Homo sapiens]            40   0.016
gi|40806223 zinc finger protein 64 isoform a [Homo sapiens]            40   0.016

>gi|31563503 activity-dependent neuroprotector [Homo sapiens]
          Length = 1102

 Score = 2257 bits (5849), Expect = 0.0
 Identities = 1102/1102 (100%), Positives = 1102/1102 (100%)

Query: 1    MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWD 60
            MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWD
Sbjct: 1    MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWD 60

Query: 61   PSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKT 120
            PSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKT
Sbjct: 61   PSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKT 120

Query: 121  LETHIKIFHAPNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIV 180
            LETHIKIFHAPNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIV
Sbjct: 121  LETHIKIFHAPNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIV 180

Query: 181  RKHIYREHFQHVAAPYIAKAGEKSLNGAVPLGSNAREESSIHCKRCLFMPKSYEALVQHV 240
            RKHIYREHFQHVAAPYIAKAGEKSLNGAVPLGSNAREESSIHCKRCLFMPKSYEALVQHV
Sbjct: 181  RKHIYREHFQHVAAPYIAKAGEKSLNGAVPLGSNAREESSIHCKRCLFMPKSYEALVQHV 240

Query: 241  IEDHERIGYQVTAMIGHTNVVVPRSKPLMLIAPKPQDKKSMGLPPRIGSLASGNVRSLPS 300
            IEDHERIGYQVTAMIGHTNVVVPRSKPLMLIAPKPQDKKSMGLPPRIGSLASGNVRSLPS
Sbjct: 241  IEDHERIGYQVTAMIGHTNVVVPRSKPLMLIAPKPQDKKSMGLPPRIGSLASGNVRSLPS 300

Query: 301  QQMVNRLSIPKPNLNSTGVNMMSSVHLQQNNYGVKSVGQGYSVGQSMRLGLGGNAPVSIP 360
            QQMVNRLSIPKPNLNSTGVNMMSSVHLQQNNYGVKSVGQGYSVGQSMRLGLGGNAPVSIP
Sbjct: 301  QQMVNRLSIPKPNLNSTGVNMMSSVHLQQNNYGVKSVGQGYSVGQSMRLGLGGNAPVSIP 360

Query: 361  QQSQSVKQLLPSGNGRSYGLGSEQRSQAPARYSLQSANASSLSSGQLKSPSLSQSQASRV 420
            QQSQSVKQLLPSGNGRSYGLGSEQRSQAPARYSLQSANASSLSSGQLKSPSLSQSQASRV
Sbjct: 361  QQSQSVKQLLPSGNGRSYGLGSEQRSQAPARYSLQSANASSLSSGQLKSPSLSQSQASRV 420

Query: 421  LGQSSSKPAAAATGPPPGNTSSTQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANY 480
            LGQSSSKPAAAATGPPPGNTSSTQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANY
Sbjct: 421  LGQSSSKPAAAATGPPPGNTSSTQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANY 480

Query: 481  IMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHIDEEM 540
            IMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHIDEEM
Sbjct: 481  IMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHIDEEM 540

Query: 541  GPKTDSTLSFDLTLQQGSHTNIHLLVTTYNLRDAPAESVAYHAQNNPPVPPKPQPKVQEK 600
            GPKTDSTLSFDLTLQQGSHTNIHLLVTTYNLRDAPAESVAYHAQNNPPVPPKPQPKVQEK
Sbjct: 541  GPKTDSTLSFDLTLQQGSHTNIHLLVTTYNLRDAPAESVAYHAQNNPPVPPKPQPKVQEK 600

Query: 601  ADIPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKL 660
            ADIPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKL
Sbjct: 601  ADIPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKL 660

Query: 661  TYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKTNAPSRLNQSPSLAPVKRTYE 720
            TYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKTNAPSRLNQSPSLAPVKRTYE
Sbjct: 661  TYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKTNAPSRLNQSPSLAPVKRTYE 720

Query: 721  QMEFPLLKKRKLDDDSDSPSFFEEKPEEPVVLALDPKGHEDDSYEARKSFLTKYFNKQPY 780
            QMEFPLLKKRKLDDDSDSPSFFEEKPEEPVVLALDPKGHEDDSYEARKSFLTKYFNKQPY
Sbjct: 721  QMEFPLLKKRKLDDDSDSPSFFEEKPEEPVVLALDPKGHEDDSYEARKSFLTKYFNKQPY 780

Query: 781  PTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDF 840
            PTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDF
Sbjct: 781  PTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDF 840

Query: 841  DAEWLFENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVE 900
            DAEWLFENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVE
Sbjct: 841  DAEWLFENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVE 900

Query: 901  PKISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQD 960
            PKISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQD
Sbjct: 901  PKISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQD 960

Query: 961  DVVEWKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQ 1020
            DVVEWKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQ
Sbjct: 961  DVVEWKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQ 1020

Query: 1021 GDREQLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNM 1080
            GDREQLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNM
Sbjct: 1021 GDREQLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNM 1080

Query: 1081 TDGVAEPMHGSLAGVKLSSQQA 1102
            TDGVAEPMHGSLAGVKLSSQQA
Sbjct: 1081 TDGVAEPMHGSLAGVKLSSQQA 1102


>gi|12229217 activity-dependent neuroprotector [Homo sapiens]
          Length = 1102

 Score = 2257 bits (5849), Expect = 0.0
 Identities = 1102/1102 (100%), Positives = 1102/1102 (100%)

Query: 1    MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWD 60
            MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWD
Sbjct: 1    MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWD 60

Query: 61   PSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKT 120
            PSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKT
Sbjct: 61   PSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKT 120

Query: 121  LETHIKIFHAPNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIV 180
            LETHIKIFHAPNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIV
Sbjct: 121  LETHIKIFHAPNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIV 180

Query: 181  RKHIYREHFQHVAAPYIAKAGEKSLNGAVPLGSNAREESSIHCKRCLFMPKSYEALVQHV 240
            RKHIYREHFQHVAAPYIAKAGEKSLNGAVPLGSNAREESSIHCKRCLFMPKSYEALVQHV
Sbjct: 181  RKHIYREHFQHVAAPYIAKAGEKSLNGAVPLGSNAREESSIHCKRCLFMPKSYEALVQHV 240

Query: 241  IEDHERIGYQVTAMIGHTNVVVPRSKPLMLIAPKPQDKKSMGLPPRIGSLASGNVRSLPS 300
            IEDHERIGYQVTAMIGHTNVVVPRSKPLMLIAPKPQDKKSMGLPPRIGSLASGNVRSLPS
Sbjct: 241  IEDHERIGYQVTAMIGHTNVVVPRSKPLMLIAPKPQDKKSMGLPPRIGSLASGNVRSLPS 300

Query: 301  QQMVNRLSIPKPNLNSTGVNMMSSVHLQQNNYGVKSVGQGYSVGQSMRLGLGGNAPVSIP 360
            QQMVNRLSIPKPNLNSTGVNMMSSVHLQQNNYGVKSVGQGYSVGQSMRLGLGGNAPVSIP
Sbjct: 301  QQMVNRLSIPKPNLNSTGVNMMSSVHLQQNNYGVKSVGQGYSVGQSMRLGLGGNAPVSIP 360

Query: 361  QQSQSVKQLLPSGNGRSYGLGSEQRSQAPARYSLQSANASSLSSGQLKSPSLSQSQASRV 420
            QQSQSVKQLLPSGNGRSYGLGSEQRSQAPARYSLQSANASSLSSGQLKSPSLSQSQASRV
Sbjct: 361  QQSQSVKQLLPSGNGRSYGLGSEQRSQAPARYSLQSANASSLSSGQLKSPSLSQSQASRV 420

Query: 421  LGQSSSKPAAAATGPPPGNTSSTQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANY 480
            LGQSSSKPAAAATGPPPGNTSSTQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANY
Sbjct: 421  LGQSSSKPAAAATGPPPGNTSSTQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANY 480

Query: 481  IMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHIDEEM 540
            IMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHIDEEM
Sbjct: 481  IMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHIDEEM 540

Query: 541  GPKTDSTLSFDLTLQQGSHTNIHLLVTTYNLRDAPAESVAYHAQNNPPVPPKPQPKVQEK 600
            GPKTDSTLSFDLTLQQGSHTNIHLLVTTYNLRDAPAESVAYHAQNNPPVPPKPQPKVQEK
Sbjct: 541  GPKTDSTLSFDLTLQQGSHTNIHLLVTTYNLRDAPAESVAYHAQNNPPVPPKPQPKVQEK 600

Query: 601  ADIPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKL 660
            ADIPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKL
Sbjct: 601  ADIPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKL 660

Query: 661  TYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKTNAPSRLNQSPSLAPVKRTYE 720
            TYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKTNAPSRLNQSPSLAPVKRTYE
Sbjct: 661  TYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKTNAPSRLNQSPSLAPVKRTYE 720

Query: 721  QMEFPLLKKRKLDDDSDSPSFFEEKPEEPVVLALDPKGHEDDSYEARKSFLTKYFNKQPY 780
            QMEFPLLKKRKLDDDSDSPSFFEEKPEEPVVLALDPKGHEDDSYEARKSFLTKYFNKQPY
Sbjct: 721  QMEFPLLKKRKLDDDSDSPSFFEEKPEEPVVLALDPKGHEDDSYEARKSFLTKYFNKQPY 780

Query: 781  PTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDF 840
            PTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDF
Sbjct: 781  PTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDF 840

Query: 841  DAEWLFENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVE 900
            DAEWLFENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVE
Sbjct: 841  DAEWLFENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVE 900

Query: 901  PKISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQD 960
            PKISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQD
Sbjct: 901  PKISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQD 960

Query: 961  DVVEWKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQ 1020
            DVVEWKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQ
Sbjct: 961  DVVEWKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQ 1020

Query: 1021 GDREQLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNM 1080
            GDREQLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNM
Sbjct: 1021 GDREQLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNM 1080

Query: 1081 TDGVAEPMHGSLAGVKLSSQQA 1102
            TDGVAEPMHGSLAGVKLSSQQA
Sbjct: 1081 TDGVAEPMHGSLAGVKLSSQQA 1102


>gi|7662346 ADNP homeobox 2 [Homo sapiens]
          Length = 1131

 Score =  249 bits (637), Expect = 8e-66
 Identities = 182/548 (33%), Positives = 257/548 (46%), Gaps = 102/548 (18%)

Query: 352  GGNAPVSIPQQSQSVKQLLPSGNGRSYGLGSEQRSQAPARYSLQSANASSLSSGQLKSPS 411
            GG A V+ PQ      QLLPSG            + AP   S+            + SP 
Sbjct: 629  GGLATVAPPQMPI---QLLPSG------------AAAPMAGSMPG----------MPSPP 663

Query: 412  LSQSQASRVLGQSSSKPAAAATGPPPGNTSSTQKWKICTICNELFPENVYSVHFEKEHK- 470
            +  + A  V  Q+SS  +AA T          ++WK C +CNELFP NVY VH E  HK 
Sbjct: 664  VLVNAAQSVFVQASS--SAADTNQV---LKQAKQWKTCPVCNELFPSNVYQVHMEVAHKH 718

Query: 471  ----------AEKVPAVANYIMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRST 520
                       EK+ A A ++  +   T +CL C   +  + L++H+L+HGL C +C  T
Sbjct: 719  SESKSGEKLEPEKLAACAPFLKWMREKTVRCLSCKCLVSEEELIHHLLMHGLGCLFCPCT 778

Query: 521  FNDVEKMAAHMRMVHIDEEMGPKTDSTLSFDLTLQ-QGSHTNIHLLVTTYNLRDAPAESV 579
            F+D++ ++ H R  H+ ++  P   S   F L +   G+    HL   T   ++   E  
Sbjct: 779  FHDIKGLSEHSRNRHLGKKKLPMDYSNRGFQLDVDANGNLLFPHLDFITILPKEKLGERE 838

Query: 580  AYHAQNNPPVPPKPQPKVQEKADIPV--KSSPQA-AVPYKKDVGKTLCPLCFSILKGPI- 635
             Y A             +  K+ +PV  K  PQA   P       + CP CF    GP  
Sbjct: 839  VYLAI---------LAGIHSKSLVPVYVKVRPQAEGTPGSTGKRVSTCPFCF----GPFV 885

Query: 636  -SDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQ 694
             ++A   HL+ERH ++ TVH V K   +KCIHC GVYT NMT + I +HLV CR   K  
Sbjct: 886  TTEAYELHLKERHHIMPTVHTVLKSPAFKCIHCCGVYTGNMTLAAIAVHLVRCRSAPK-D 944

Query: 695  NGQDKTNAPSRLNQSPSLAPVKRTYEQMEFPLLKKRKLDD---DSDSPSFFEEKP----- 746
            +  D    P  ++ S  L           F +  KRKL D    ++     EE+P     
Sbjct: 945  SSSDLQAQPGFIHNSELLLVSGEVMHDSSFSV--KRKLPDGHLGAEDQRHGEEQPPILNA 1002

Query: 747  ------------------------EEPVV-------LALDPKGHEDDSYEARKSFLTKYF 775
                                    E P+V       LALDPK +E  SYE +K FL  YF
Sbjct: 1003 DAAPGPEKVTSVVPFKRQRNESRTEGPIVKDEALQILALDPKKYEGRSYEEKKQFLKDYF 1062

Query: 776  NKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVK 835
            +K+PYP+++EIE L++  W+WK D+AS F  +R  C++  + +KP VLLGF+M EL  VK
Sbjct: 1063 HKKPYPSKKEIELLSSLFWVWKIDVASFFGKRRYICMKAIKNHKPSVLLGFDMSELKNVK 1122

Query: 836  HEMDFDAE 843
            H ++F+ E
Sbjct: 1123 HRLNFEYE 1130



 Score =  172 bits (436), Expect = 2e-42
 Identities = 110/379 (29%), Positives = 183/379 (48%), Gaps = 37/379 (9%)

Query: 1   MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWD 60
           MFQ+PV NL ++RK RK VK IL DIGL+ CKE ++D K F+P + Y  NT+W DV LW+
Sbjct: 1   MFQIPVENLDNIRKVRKKVKGILVDIGLDSCKELLKDLKGFDPGEKYFHNTSWGDVSLWE 60

Query: 61  PSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKT 120
           PS  K   YRTKP+CC  C +S+K  +++K+H    H ++ +  +++ CP C F +  K 
Sbjct: 61  PS-GKKVRYRTKPYCCGLCKYSTKVLTSFKNHLHRYHEDEIDQELVIPCPNCVFASQPKV 119

Query: 121 LETHIKIFHAPNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIV 180
           +  H ++FHAP     + +++   +       K  ++D +    + C KC + + LY  +
Sbjct: 120 VGRHFRMFHAPVRKVQNYTVNILGE------TKSSRSDVIS---FTCLKCNFSNTLYYSM 170

Query: 181 RKHIYREHFQHVAAPYIA----KAGEKSLNGAVPLGSNAREESSIHCKRCLFMPKSYEAL 236
           +KH+   HF ++   Y      + GE+                  +CK+C     S +AL
Sbjct: 171 KKHVLVAHFHYLINSYFGLRTEEMGEQPKTNDTVSIEKIPPPDKYYCKKCNANASSQDAL 230

Query: 237 VQHVI--EDHERIGYQVTAMIGHTNVVVPRSKPLML--IAPKPQDKKSMGLPPRIGSLAS 292
           + H++  + H  +  ++ ++I      + R+  L    IAPKP           + + A+
Sbjct: 231 MYHILTSDIHRDLENKLRSVISEH---IKRTGLLKQTHIAPKP--------AAHLAAPAN 279

Query: 293 GNVRSLPSQQMVNRLSIPKPNLNSTGVNMMSSVHLQQN-----NYGVKSVGQGYSVGQSM 347
           G+  S P+Q     L++P+   NS        V + Q       +   + GQ +    S 
Sbjct: 280 GSAPSAPAQPPCFHLALPQ---NSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSS 336

Query: 348 RLGLGGNAPVSIPQQSQSV 366
            L +G N+    P   Q V
Sbjct: 337 PLPVGQNSLTLQPPAPQPV 355


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 51/236 (21%), Positives = 100/236 (42%), Gaps = 25/236 (10%)

Query: 847  ENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISND 906
            ++ +  DS  ++   +    +    D S SDS ++ + +S++S +  D         S+D
Sbjct: 556  DSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD---------SSD 606

Query: 907  NPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWK 966
            + +         D+S+S +  D K D SK E+   ++  +K   + S+S  D  D  +  
Sbjct: 607  SSDS-------SDSSDSSDSSDSKSDSSKSES-DSSDSDSKSDSSDSNSS-DSSDNSDSS 657

Query: 967  DGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDREQL 1026
            D ++ S S   S   SD  D++        SD S  S+ + SS+ +    ++     +  
Sbjct: 658  DSSNSSNSSDSSDS-SDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSS 716

Query: 1027 KWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNMTD 1082
               NS+    +   S D S   N+S++ +   +      +++ DS D     N +D
Sbjct: 717  DSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS------SNSSDSSDSSDSSNSSD 766



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 51/247 (20%), Positives = 96/247 (38%), Gaps = 4/247 (1%)

Query: 839  DFDAEWLFENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFE 898
            D D+     + D  DS  + S  ++   +    D  SSDS ++   +S+ S    D    
Sbjct: 551  DSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDS 610

Query: 899  VEPKISNDNPEEHVLKVIPE-DASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSE- 956
             +   S+D+ +        E D+S+S+ K D  +  S   + +     +    N+SDS  
Sbjct: 611  SDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSD 670

Query: 957  -VDQDDVVEWKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKK 1015
              D  D     D ++ S+S   S   +  E +       + S +SS S ++ SS  +   
Sbjct: 671  SSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSS-DSDSS 729

Query: 1016 KATMQGDREQLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGE 1075
             ++   D       + S        S D S   N+S++ +   +      +++ DS D  
Sbjct: 730  NSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSS 789

Query: 1076 QFDNMTD 1082
               + +D
Sbjct: 790  NSSDSSD 796



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 50/235 (21%), Positives = 90/235 (38%), Gaps = 15/235 (6%)

Query: 847  ENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSP--FDPVFEVEPKIS 904
            ++ D  DS  + S  +D   +    D S+S    +  + SN S S    D     +   S
Sbjct: 711  DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770

Query: 905  NDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVE 964
            +D+ +         D+S S +  D        ++ + ++       ++SDS    D    
Sbjct: 771  SDSSDS-------SDSSNSSDSNDSSNSSDSSDSSNSSDSSNS--SDSSDSSDSSDSDSS 821

Query: 965  WKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDRE 1024
                +S S     S   SD  D++ +   G+ SD S++S+ + SS  +    ++   D  
Sbjct: 822  NSSDSSNSSDSSDSSNSSDSSDSS-DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS 880

Query: 1025 QLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDN 1079
                 N S    +   S D S   ++  +D   S+   +  NS+  SE     DN
Sbjct: 881  DSSDSNESSNSSD---SSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN 932



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 47/233 (20%), Positives = 92/233 (39%), Gaps = 21/233 (9%)

Query: 850  DEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPE 909
            D  DS  ++  ++    +   +   SSDS  + E   +   S  D     +   SN +  
Sbjct: 667  DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDS 726

Query: 910  EHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKDGA 969
            +        D+S S +  D  +  +  ++   ++       N+SDS  D  D  +  D +
Sbjct: 727  DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS-----NSSDSS-DSSDSSDSSDSS 780

Query: 970  SPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDREQLKWK 1029
            + S+S   S        N+ +    + S +SS S D+  S  ++   ++   D       
Sbjct: 781  NSSDSNDSS--------NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSD------S 826

Query: 1030 NSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNMTD 1082
            ++S    +   S D S   ++S+  +  S+ + +  NS+ DS D     N +D
Sbjct: 827  SNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSS-DSSDSSDSSNSSD 878



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 50/240 (20%), Positives = 96/240 (40%), Gaps = 19/240 (7%)

Query: 847  ENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEE-------ESNESGSPFDPVFEV 899
            ++ D  DS   +S ++D   +    D  SSDS  + +        +S+ES +  D     
Sbjct: 878  DSSDSSDSN-ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSS 936

Query: 900  EPKISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQ 959
            +   S+D+ +         D+S S +  +  +  +  ++       +    N+SDS  D 
Sbjct: 937  DSSNSSDSSDS-------SDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSS-DS 988

Query: 960  DDVVEWKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATM 1019
             D  +  D +  S S   S   SD  D++        SD S+ S+ + SS  +    ++ 
Sbjct: 989  SDSSDSSDSSDSSNSSDSSDS-SDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047

Query: 1020 QGDREQLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDN 1079
              D       + S    +   S D S   ++S++ E  S+   +  NS+  S+  +  D+
Sbjct: 1048 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSE--SSDSSDSSNSSDSSDSSDSSDS 1105



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 47/235 (20%), Positives = 81/235 (34%), Gaps = 9/235 (3%)

Query: 848  NHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDN 907
            N  +     N+S ++D   +    D S S    N  + S+ S S  D         SND+
Sbjct: 730  NSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS-DSSDSSNSSDSNDS 788

Query: 908  PEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKD 967
                       D+S S +  +  +     ++       +    N+SDS     D     D
Sbjct: 789  SNSSD----SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS----DSSNSSD 840

Query: 968  GASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDREQLK 1027
             +  S+S  GS   S    ++      + S +SS S D+  S  + +   +         
Sbjct: 841  SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNS 900

Query: 1028 WKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNMTD 1082
              + S        S D S   ++SE+     N      +++ DS D     N +D
Sbjct: 901  SDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSD 955



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 49/243 (20%), Positives = 92/243 (37%), Gaps = 35/243 (14%)

Query: 847  ENHDEKDSRVNASKTADKKLNLGK-------EDDSSSDSFENLEEESNESGSPFDPVFEV 899
            E+ +   SR +AS  +D+  + G        EDD S  + +    +SN +G         
Sbjct: 480  ESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNG--------- 530

Query: 900  EPKISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQ 959
                +N N +         D S+S +      D    ++ + ++       ++SDS    
Sbjct: 531  ----NNGNDD--------NDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSS 578

Query: 960  DDVVEWKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATM 1019
            D        +S S+S   S   S    N+ +    + S +SS S D+  SK  + K  + 
Sbjct: 579  D------SDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632

Query: 1020 QGDREQLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDN 1079
              D +  K  +S     +   + D S   N+S + +   +      +S+ DS +     +
Sbjct: 633  SSDSDS-KSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691

Query: 1080 MTD 1082
             +D
Sbjct: 692  SSD 694



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 45/236 (19%), Positives = 85/236 (36%), Gaps = 11/236 (4%)

Query: 847  ENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISND 906
            ++ D  DS  + S  +    N     DSS+ S ++ +   +  GS  D     +   S+D
Sbjct: 808  DSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS-DSSDSSDSSDGSDSDSSNRSDSSNSSD 866

Query: 907  NPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWK 966
            + +         D+S S +  D  +      +   ++       ++SDS    D      
Sbjct: 867  SSDS-------SDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSN 919

Query: 967  DGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDREQL 1026
               S   S       S    N+ +    + S  SS S ++  S  ++    +   D    
Sbjct: 920  SSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDS 979

Query: 1027 KWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNMTD 1082
               + S    +   S D S   N+S++ +  S+   +  NS+ DS +     N +D
Sbjct: 980  SNSSDSSDSSDSSDSSDSSDSSNSSDSSD--SSDSSDSSNSS-DSSNSSDSSNSSD 1032



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 48/249 (19%), Positives = 97/249 (38%), Gaps = 24/249 (9%)

Query: 847  ENHDEKDSRVNASKT----ADKKLNLGKEDDSSSDSFENLEE----------ESNESGSP 892
            ++ D  DS+ ++SK+    +D        D +SSDS +N +           +S++S   
Sbjct: 615  DSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDS 674

Query: 893  FDPVFEVEPKISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNA 952
             D     +   S+D+ +        E +  S+       D S     + ++  +    ++
Sbjct: 675  SDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDS 734

Query: 953  SDSEVDQDDVVEWKDGASPSESGPGSQQV--SDFEDNTCEMKPGTWSDESSQSEDARSSK 1010
            SDS  +  D  +  D ++ S+S   S     SD  D++ +    + S  SS S D+ +S 
Sbjct: 735  SDSS-NSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSS-DSSDSSDSSNSSDSNDSSNSS 792

Query: 1011 PAAKKKATMQGDREQLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTID 1070
             ++    +           +S     +   S D S   ++S++     +      + + D
Sbjct: 793  DSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS------SDSSD 846

Query: 1071 SEDGEQFDN 1079
            S DG   D+
Sbjct: 847  SSDGSDSDS 855



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 45/242 (18%), Positives = 87/242 (35%), Gaps = 10/242 (4%)

Query: 850  DEKDSRVNASKTADKKLNLGKEDDS--------SSDSFENLEEESNESGSPFDPVFEVEP 901
            D  DS  ++  +     + G + DS        SSDS ++  + SN S S          
Sbjct: 831  DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDS-SDSSNSSDSSDSSDSNESS 889

Query: 902  KISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDD 961
              S+ +   +       D+S S +  D        E+ + ++       + S    D  D
Sbjct: 890  NSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSD 949

Query: 962  VVEWKDGASPSESGPGSQQV-SDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQ 1020
                 D ++ S+S   S    S+  D++        SD S  S+ + SS  +    ++  
Sbjct: 950  SSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1009

Query: 1021 GDREQLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNM 1080
             D       + S    +   S D S   ++S++ +   +      +++ DS D     + 
Sbjct: 1010 SDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1069

Query: 1081 TD 1082
            +D
Sbjct: 1070 SD 1071



 Score = 39.7 bits (91), Expect = 0.016
 Identities = 49/246 (19%), Positives = 91/246 (36%), Gaps = 11/246 (4%)

Query: 850  DEKDSRVNASKTADKKLNLGKEDDSS--SDSFENLEEESNESGSPFDPVFEVEPKISNDN 907
            D  DS  + S  +    +     DSS  SDS ++ + +S+ S S  D         S+D+
Sbjct: 586  DSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDS 645

Query: 908  PEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKD 967
                       D S+S +  +        ++   ++  +    + S    D  D     +
Sbjct: 646  NSSD-----SSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSE 700

Query: 968  GASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSED-ARSSKPAAKKKATMQGDREQL 1026
             +  S+S       SD  D++      + S  SS S D + SS  +    ++   D    
Sbjct: 701  SSDSSDSSDSDS--SDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758

Query: 1027 KWKNSSYGKVEGFWSKDQSQWKNASE-NDERLSNPQIEWQNSTIDSEDGEQFDNMTDGVA 1085
               ++S    +   S D S   N+S+ ND   S+   +  NS+  S   +  D+     +
Sbjct: 759  SDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDS 818

Query: 1086 EPMHGS 1091
            +  + S
Sbjct: 819  DSSNSS 824



 Score = 39.7 bits (91), Expect = 0.016
 Identities = 44/229 (19%), Positives = 89/229 (38%), Gaps = 12/229 (5%)

Query: 857  NASKTADKKLNLGKEDDS-SSDSFENLEEESNESGSPFDPVFEVEPKISNDNPEEHVLKV 915
            N+S ++D   +    D S SSD  ++     ++S +  D     +   S+D+ +      
Sbjct: 828  NSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS----- 882

Query: 916  IPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKDGASPSESG 975
               D++ES    D  +  +  ++       +    ++S+S  D  +     D ++ S+S 
Sbjct: 883  --SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS-DSSESSNSSDNSNSSDSS 939

Query: 976  PGSQQVSDFED--NTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDREQLKWKNSSY 1033
              S   SD  D  N+ +    + S  SS S D+ SS  +    ++   D       + S 
Sbjct: 940  -NSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS 998

Query: 1034 GKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNMTD 1082
                   S D S   ++S + +  ++      + + DS D     + +D
Sbjct: 999  DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047



 Score = 34.7 bits (78), Expect = 0.51
 Identities = 43/214 (20%), Positives = 79/214 (36%), Gaps = 18/214 (8%)

Query: 870  KEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPEEHVLKVIPEDA-SESEEKLD 928
            K +  +     N   +SN  G  +D     +  +  D+P         +DA SES+    
Sbjct: 429  KSEPGNKVGHSNTGSDSNSDG--YDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSS 486

Query: 929  QKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKDGASPSESGPGSQQVSDFEDNT 988
             + D S         + +K   N SDS+  +DD  +     + S+S       +D  D +
Sbjct: 487  SRGDAS------YNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKS 540

Query: 989  CEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDREQLKWKNSSYGKVEGFWSKDQSQWK 1048
               K G      S S D+ +S  ++    +   D       +SS          D S   
Sbjct: 541  DSGK-GKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSS--------DSDSSDSS 591

Query: 1049 NASENDERLSNPQIEWQNSTIDSEDGEQFDNMTD 1082
            ++  +D   S+   +  +S+  S+  +  D+ +D
Sbjct: 592  DSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD 625


>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precursor
            [Homo sapiens]
          Length = 513

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 53/237 (22%), Positives = 102/237 (43%), Gaps = 30/237 (12%)

Query: 852  KDSRVNASKTADKKLNLGKED---DSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNP 908
            K      S + D  L+  + D   DS  DS ENL +E +++         V+   S  + 
Sbjct: 292  KSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQN---------VDGPSSESSQ 342

Query: 909  EEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKDG 968
            E ++     E++SES+E++  +  G         +  T  + +  DS+  ++D       
Sbjct: 343  EANLSS--QENSSESQEEVVSESRGDN------PDPTTSYVEDQEDSDSSEEDSSHTLSH 394

Query: 969  ASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDREQ--L 1026
            +        +   S    N  E  P +  DE+S S++   S  ++ +  + +   E+   
Sbjct: 395  SKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDS 454

Query: 1027 KWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSED----GEQFDN 1079
              ++SS  K +     + ++ K++SE D +L N +IE +  T+D+      G+Q DN
Sbjct: 455  DSQDSSRSKEDS----NSTESKSSSEEDGQLKNIEIESRKLTVDAYHNKPIGDQDDN 507



 Score = 32.3 bits (72), Expect = 2.5
 Identities = 51/255 (20%), Positives = 96/255 (37%), Gaps = 52/255 (20%)

Query: 847  ENHDEKDSR------VNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVE 900
            +N D  DS+         S++ +  +  G + +SS      L++E  +S  P      + 
Sbjct: 169  DNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPES----IR 224

Query: 901  PKISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQD 960
             +  N       +K   +++ E+ E+ + ++ G       L E P++ +   S    + D
Sbjct: 225  SERGNSRMNSAGMK--SKESGENSEQANTQDSGGS----QLLEHPSRKIFRKSRISEEDD 278

Query: 961  DVVEWKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQ 1020
                                 S+ +DN    +  + S E+S S D   S+P    K   Q
Sbjct: 279  R--------------------SELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQ 318

Query: 1021 GD-REQLKWKNSSYGKVEGFWSKDQ-----SQWKNASENDERL--------SNPQIEWQN 1066
             D +E L  + S    V+G  S+       S  +N+SE+ E +         +P   +  
Sbjct: 319  EDSKENLSQEESQ--NVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVE 376

Query: 1067 STIDSEDGEQFDNMT 1081
               DS+  E+  + T
Sbjct: 377  DQEDSDSSEEDSSHT 391



 Score = 31.6 bits (70), Expect = 4.3
 Identities = 29/121 (23%), Positives = 50/121 (41%), Gaps = 12/121 (9%)

Query: 848 NHDEKDSRVN-ASKTADKKLNLGKE-----DDSSSDSFENLEEESNESGSPFDPVFEVEP 901
           +H + +SR   A   + + LN  +E     +D +S S E L+  S+ + S  +     E 
Sbjct: 393 SHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSE-----ES 447

Query: 902 KISNDNPEEHVLKVIPEDASESEEKLDQKEDGS-KYETIHLTEEPTKLMHNASDSEVDQD 960
               D+ +        ED++ +E K   +EDG  K   I   +      HN    + D +
Sbjct: 448 HSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVDAYHNKPIGDQDDN 507

Query: 961 D 961
           D
Sbjct: 508 D 508


>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
            precursor [Homo sapiens]
          Length = 497

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 53/237 (22%), Positives = 102/237 (43%), Gaps = 30/237 (12%)

Query: 852  KDSRVNASKTADKKLNLGKED---DSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNP 908
            K      S + D  L+  + D   DS  DS ENL +E +++         V+   S  + 
Sbjct: 276  KSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQN---------VDGPSSESSQ 326

Query: 909  EEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKDG 968
            E ++     E++SES+E++  +  G         +  T  + +  DS+  ++D       
Sbjct: 327  EANLSS--QENSSESQEEVVSESRGDN------PDPTTSYVEDQEDSDSSEEDSSHTLSH 378

Query: 969  ASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDREQ--L 1026
            +        +   S    N  E  P +  DE+S S++   S  ++ +  + +   E+   
Sbjct: 379  SKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDS 438

Query: 1027 KWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSED----GEQFDN 1079
              ++SS  K +     + ++ K++SE D +L N +IE +  T+D+      G+Q DN
Sbjct: 439  DSQDSSRSKEDS----NSTESKSSSEEDGQLKNIEIESRKLTVDAYHNKPIGDQDDN 491



 Score = 32.3 bits (72), Expect = 2.5
 Identities = 51/255 (20%), Positives = 96/255 (37%), Gaps = 52/255 (20%)

Query: 847  ENHDEKDSR------VNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVE 900
            +N D  DS+         S++ +  +  G + +SS      L++E  +S  P      + 
Sbjct: 153  DNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPES----IR 208

Query: 901  PKISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQD 960
             +  N       +K   +++ E+ E+ + ++ G       L E P++ +   S    + D
Sbjct: 209  SERGNSRMNSAGMK--SKESGENSEQANTQDSGGS----QLLEHPSRKIFRKSRISEEDD 262

Query: 961  DVVEWKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQ 1020
                                 S+ +DN    +  + S E+S S D   S+P    K   Q
Sbjct: 263  R--------------------SELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQ 302

Query: 1021 GD-REQLKWKNSSYGKVEGFWSKDQ-----SQWKNASENDERL--------SNPQIEWQN 1066
             D +E L  + S    V+G  S+       S  +N+SE+ E +         +P   +  
Sbjct: 303  EDSKENLSQEESQ--NVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVE 360

Query: 1067 STIDSEDGEQFDNMT 1081
               DS+  E+  + T
Sbjct: 361  DQEDSDSSEEDSSHT 375



 Score = 31.6 bits (70), Expect = 4.3
 Identities = 29/121 (23%), Positives = 50/121 (41%), Gaps = 12/121 (9%)

Query: 848 NHDEKDSRVN-ASKTADKKLNLGKE-----DDSSSDSFENLEEESNESGSPFDPVFEVEP 901
           +H + +SR   A   + + LN  +E     +D +S S E L+  S+ + S  +     E 
Sbjct: 377 SHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSE-----ES 431

Query: 902 KISNDNPEEHVLKVIPEDASESEEKLDQKEDGS-KYETIHLTEEPTKLMHNASDSEVDQD 960
               D+ +        ED++ +E K   +EDG  K   I   +      HN    + D +
Sbjct: 432 HSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVDAYHNKPIGDQDDN 491

Query: 961 D 961
           D
Sbjct: 492 D 492


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
            sapiens]
          Length = 1220

 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 62/288 (21%), Positives = 123/288 (42%), Gaps = 19/288 (6%)

Query: 773  KYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELN 832
            K  NK    T+ +I+  A +  +  +  A     ++ K  +  EK K        +KEL 
Sbjct: 4    KQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELE 63

Query: 833  KVKHE---MDFDAEWLFENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNES 889
            ++  E   +  D E +     E +     SK   KK   GK+     +  E LE++ ++S
Sbjct: 64   ELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKS 123

Query: 890  GSPFDPVFEVEPKISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLM 949
                 P  +VE    +D+ ++     +P+ A    +K ++K DGS+ +  +  +   +  
Sbjct: 124  KKTAKP--KVEMYSGSDDDDD--FNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSR 179

Query: 950  HNASDSEVDQ-DDVVEWKDGASPSESG-PGSQQVSDFEDNTCEMKPGTWSDESSQSEDAR 1007
             N+S    D+ D+ ++ + G   ++   PG    S  ED+    K  T + + ++ ++ R
Sbjct: 180  INSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKE-R 238

Query: 1008 SSKPAAKKKATMQGDREQLKWKNSSYGKVEGFWSKDQSQWKNASENDE 1055
              K   ++KA ++  +E+ + +            KDQS+ K +    E
Sbjct: 239  ERKKRDEEKAKLRKLKEKEELETG---------KKDQSKQKESQRKFE 277



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 13/82 (15%)

Query: 880 ENLEEESNESGSPFDPVFEVEPKISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETI 939
           EN EEE  E         E E + S +  EE       E   E E+  D+K+ G      
Sbjct: 529 ENPEEEEEEEEE------EEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKT---- 578

Query: 940 HLTEEPTKLMHNASDSEVDQDD 961
            L ++P+K M  +SDSE D DD
Sbjct: 579 -LDKKPSKEM--SSDSEYDSDD 597



 Score = 32.0 bits (71), Expect = 3.3
 Identities = 38/214 (17%), Positives = 81/214 (37%), Gaps = 24/214 (11%)

Query: 830  ELNKVKHEMDFDAEWLFENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLE----EE 885
            + NK+  +    A+   +  D  +   + SK   ++  +    +S  +S E L+    ++
Sbjct: 142  DFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQK 201

Query: 886  SNESGSPFDPVFEVEPKISNDNPEEHV---LKVIPEDASESEEKLDQKEDGSKYETIHLT 942
             N+   P        P I + N ++     +K + +  +E +E+  +K D  K +   L 
Sbjct: 202  KNQKNKP-------GPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLK 254

Query: 943  EEPT-------KLMHNASDSEVDQDDV---VEWKDGASPSESGPGSQQVSDFEDNTCEMK 992
            E+         +     S  + +++ V   V    G  P+         +  +DN  + K
Sbjct: 255  EKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKK 314

Query: 993  PGTWSDESSQSEDARSSKPAAKKKATMQGDREQL 1026
                  +  + E+    K     KAT++  +E L
Sbjct: 315  KKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEAL 348



 Score = 31.2 bits (69), Expect = 5.7
 Identities = 22/99 (22%), Positives = 40/99 (40%), Gaps = 4/99 (4%)

Query: 843 EWLFENHDEKDSRVNASKT----ADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFE 898
           +W     DE+  +V  +K      +      +E++   +  E+ EEE  E  S      E
Sbjct: 505 DWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDE 564

Query: 899 VEPKISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYE 937
            + K+S++      L   P     S+ + D  +D +K E
Sbjct: 565 EDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEE 603


>gi|114431236 zinc finger protein 462 [Homo sapiens]
          Length = 2506

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 41/176 (23%), Positives = 75/176 (42%), Gaps = 16/176 (9%)

Query: 72   KPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNA-DKKTLETHIKIFHA 130
            KPF C  C F S + S  K+H    H+ +   +    C +C+F+      L+ H    H 
Sbjct: 2052 KPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYK----CSWCSFSTMTISQLKEHSLKVHG 2107

Query: 131  PNASAPSSSL-STFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHF 189
               + P   + S     + +   K   A+ VE +       +Y +P    V++ +   H+
Sbjct: 2108 KALTLPRPRIVSLLSSHSHHSSQKATPAEEVEDS----NDSSYSEP--PDVQQQL--NHY 2159

Query: 190  QHVA-APYIAKAGEKSLNGAVPLGSNAREESSIHCKRCLFMPKSYEALVQHVIEDH 244
            Q  A A   ++     L+GA   G+  + E+ +HC+ C F     +++ +H  + H
Sbjct: 2160 QSAALARNNSRVSPVPLSGAA-AGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKH 2214



 Score = 37.7 bits (86), Expect = 0.060
 Identities = 38/176 (21%), Positives = 63/176 (35%), Gaps = 43/176 (24%)

Query: 72   KPFCCSACPFSSKFFSAYKSHFRNVHSE-DFENRILLNCPYCTFNAD-KKTLETHIKIFH 129
            K F C  C F + F SA+  H    HS    E    L CP C ++   K+ +  HI + H
Sbjct: 2218 KLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHI-VLH 2276

Query: 130  APNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHF 189
                  P             +  + K +  ++  V+ C KCT+     E +++HI + + 
Sbjct: 2277 REERVVPI------------EVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHN- 2323

Query: 190  QHVAAPYIAKAGEKSLNGAVPLGSNAREESSIHCKRCLFMPKSYEALVQHVIEDHE 245
                                       E     C+ C +  K  E L  H+ ++H+
Sbjct: 2324 ---------------------------ELKPYKCQLCYYETKHTEELDSHLRDEHK 2352



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 36/179 (20%), Positives = 65/179 (36%), Gaps = 44/179 (24%)

Query: 74   FCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETH---IKIFHA 130
            F C  C + ++       H++  H +              F A+   +  H   I+    
Sbjct: 1193 FFCQHCDYGNRTVKGVLIHYQKKHRD--------------FKANADVIRQHTATIRSLCD 1238

Query: 131  PNASAPSSSL-----STFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIY 185
             N   P+S +     +  +DK K   LK             C++C+Y  P +  +RKHI 
Sbjct: 1239 RNQKKPASCVLVSPSNLERDKTKLRALK-------------CRQCSYTSPYFYALRKHIK 1285

Query: 186  REHFQHVAAPYIAKAGEKSLNGAVPLGSNAREESSIHCKRCLFMPKSYEALVQHVIEDH 244
            ++H   + A   +      L+G +        E+  HC+ C++       L+ H    H
Sbjct: 1286 KDH-PALKATVTSIMRWAFLDGLI--------EAGYHCEWCIYSHTEPNGLLLHYQRRH 1335



 Score = 35.4 bits (80), Expect = 0.30
 Identities = 39/205 (19%), Positives = 81/205 (39%), Gaps = 30/205 (14%)

Query: 68   DYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKI 127
            D  T+ + C  C +S++       H++  H E     I +   Y         +   ++ 
Sbjct: 1108 DLSTELYYCKHCSYSNRSVVGVLVHYQKRHPE-----IKVTAKYIRQAPPTAAMMRGVEG 1162

Query: 128  FH-APNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYR 186
               +P   AP   L+  +  ++ DG        VE  +++C+ C Y +   + V  H  +
Sbjct: 1163 PQGSPRPPAPIQQLN--RSSSERDG------PPVENEMFFCQHCDYGNRTVKGVLIHYQK 1214

Query: 187  EHF----------QHVAA--PYIAKAGEKSLNGAVPLGSNAREESS----IHCKRCLFMP 230
            +H           QH A       +  +K  +  +   SN   + +    + C++C +  
Sbjct: 1215 KHRDFKANADVIRQHTATIRSLCDRNQKKPASCVLVSPSNLERDKTKLRALKCRQCSYTS 1274

Query: 231  KSYEALVQHVIEDHERIGYQVTAMI 255
              + AL +H+ +DH  +   VT+++
Sbjct: 1275 PYFYALRKHIKKDHPALKATVTSIM 1299



 Score = 35.4 bits (80), Expect = 0.30
 Identities = 37/177 (20%), Positives = 61/177 (34%), Gaps = 42/177 (23%)

Query: 76   CSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLET-HIKIFHAPNAS 134
            C  C FSS +  + + H+R+ H      + L  C  C+F    K+  T H++  H+   +
Sbjct: 2193 CEFCEFSSGYIQSIRRHYRDKHG----GKKLFKCKDCSFYTGFKSAFTMHVEAGHS---A 2245

Query: 135  APSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAA 194
             P       +                      C  C Y       +  HI     + V  
Sbjct: 2246 VPEEGPKDLR----------------------CPLCLYHTKYKRNMIDHIVLHREERVVP 2283

Query: 195  PYIAKAG-EKSLNGAVPLGSNAREESSIHCKRCLFMPKSYEALVQHVIEDHERIGYQ 250
              + ++   K L G V             C +C F   S E+L QH+ + +E   Y+
Sbjct: 2284 IEVCRSKLSKYLQGVV-----------FRCDKCTFTCSSDESLQQHIEKHNELKPYK 2329



 Score = 31.6 bits (70), Expect = 4.3
 Identities = 29/129 (22%), Positives = 48/129 (37%), Gaps = 14/129 (10%)

Query: 76   CSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNASA 135
            C  C F+S    +   H++  H E+  +   +       + D+ +  + +         A
Sbjct: 1032 CDVCSFASPNMHSVLVHYQKKHPEEKASYFRIQKTMRMVSVDRGSALSQLSF----EVGA 1087

Query: 136  PSSSLSTFKDKNKNDGLKP---KQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQ-H 191
            P S       K  N G  P        +   +YYCK C+Y +     V  H  + H +  
Sbjct: 1088 PMS------PKMSNMGSPPPPQPPPPDLSTELYYCKHCSYSNRSVVGVLVHYQKRHPEIK 1141

Query: 192  VAAPYIAKA 200
            V A YI +A
Sbjct: 1142 VTAKYIRQA 1150


>gi|157676340 zinc finger protein 142 [Homo sapiens]
          Length = 1687

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 45/184 (24%), Positives = 74/184 (40%), Gaps = 28/184 (15%)

Query: 72   KPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNAD-------KKTLETH 124
            KP+ C  CP++    S  K H R +H E  E + L  CP C +            T  T 
Sbjct: 1478 KPYHCHLCPYACADPSRLKYHMR-IHKE--ERKYL--CPECGYKCKWVNQLKYHMTKHTG 1532

Query: 125  IKIFHAPNASAPSSSLSTFKDKNKNDGLKPKQADSVEQA-VYYCKKCTYRDPLYEIVRKH 183
            +K +  P     +         N+ D L+  Q     +A  + C++C        ++R H
Sbjct: 1533 LKPYQCPECEYCT---------NRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTH 1583

Query: 184  IYREHFQHVAAPYIAKAGEKSLNGAVPLGSNAREESSIH---CKRCLFMPKSYEALVQHV 240
            + R+H +  A PY+     ++   A  L  +A   +  H   C+ C +  K    +V+HV
Sbjct: 1584 L-RKHSE--AKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHV 1640

Query: 241  IEDH 244
               H
Sbjct: 1641 RRHH 1644



 Score = 38.1 bits (87), Expect = 0.046
 Identities = 43/196 (21%), Positives = 75/196 (38%), Gaps = 25/196 (12%)

Query: 76   CSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNAD-KKTLETHIKIFH----- 129
            CS+CP +    S  + H   VH +   +     CP C ++   +  +  H+   H     
Sbjct: 1230 CSSCPQTFGTNSKLRLHRLRVHDKTPTHF----CPLCDYSGYLRHDITRHVNSCHQGTPA 1285

Query: 130  --APNASAPSSSLSTFKDKNKNDGLKPKQ------ADSVEQAVYYCKKCTYRDPLYEIVR 181
                   A  SS +  K        +P Q      A++ E  ++ C +C    P    +R
Sbjct: 1286 FACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLH-CSRCGLLCPSPASLR 1344

Query: 182  KHIYREHFQHVAAPYIAKAGEKSLNGAVPLGSNAREESSIH-CKRCLFMPKSYEALVQHV 240
             H  ++H +         A +++    + L  + R++   H C+ C F  +    LV+H 
Sbjct: 1345 GHTRKQHPRLECG-----ACQEAFPSRLALDEHRRQQHFSHRCQLCDFAARERVGLVKHY 1399

Query: 241  IEDHERIGYQVTAMIG 256
            +E HE     V A  G
Sbjct: 1400 LEQHEETSAAVAASDG 1415



 Score = 34.7 bits (78), Expect = 0.51
 Identities = 39/172 (22%), Positives = 64/172 (37%), Gaps = 13/172 (7%)

Query: 76  CSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTF-NADKKTLETHIKIFHAPNAS 134
           C+ CPF++    AY+ H   +H+ +     +  CP C F  A K+ L  H+ +       
Sbjct: 374 CTFCPFATFNPVAYQDHVGKMHAHE----KIHQCPECNFATAHKRVLIRHMLLHTGEKPH 429

Query: 135 APSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAA 194
                  T +D +    L            Y C +C Y       +R H+ R+H   +  
Sbjct: 430 KCELCDFTCRDVSY---LSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHM-RKHAGDLR- 484

Query: 195 PYIAKAGEKSLNGAVPLGSN--AREESSIHCKRCLFMPKSYEALVQHVIEDH 244
            Y         + A  L S+    +  S+ C+ C F  K    L +H+   H
Sbjct: 485 -YQCNQCSYRCHRADQLSSHKLRHQGKSLMCEVCAFACKRKYELQKHMASQH 535


>gi|169213065 PREDICTED: similar to hCG1654128 [Homo sapiens]
          Length = 851

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 6/143 (4%)

Query: 869  GKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPEEHVL---KVIPEDASESEE 925
            G ED S ++   + +E+  E  SP +     E    + +P EH +   +  PEDA  +E 
Sbjct: 72   GPEDASPTEHGVDQQEDGPEDASPTEHGVNQEDGPEDASPTEHGVDQQEDGPEDARPTEH 131

Query: 926  KLDQKEDGSKYETI--HLTEEPTKLMHNASDSEVDQDDVVEWKDGASPSESGPGSQQVSD 983
             +DQ+EDG +  ++  H  ++      +AS +E   D   +  + ASP+E   G  Q  D
Sbjct: 132  GIDQEEDGPEDASLTEHGVDQQEDGPEDASPTEHGIDQEEDGPEDASPTEHEHGVDQEED 191

Query: 984  FEDNTCEMKPGTWSDESSQSEDA 1006
              ++    + G    E    EDA
Sbjct: 192  GPEDASPTEHGV-DQEEDGPEDA 213



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 41/155 (26%), Positives = 63/155 (40%), Gaps = 23/155 (14%)

Query: 869  GKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPEEHVLKVI--------PEDA 920
            G ED S ++   + +E+  E   P +   + E     D PE+  L           PEDA
Sbjct: 105  GPEDASPTEHGVDQQEDGPEDARPTEHGIDQE----EDGPEDASLTEHGVDQQEDGPEDA 160

Query: 921  SESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKDGASPSESGP---- 976
            S +E  +DQ+EDG +         PT+  H     E   +D    + G    E GP    
Sbjct: 161  SPTEHGIDQEEDGPE------DASPTEHEHGVDQEEDGPEDASPTEHGVDQEEDGPEDAS 214

Query: 977  GSQQVSDFEDNTCEMKPGTWS-DESSQSEDARSSK 1010
             ++   D ED   + +P     D+    EDAR ++
Sbjct: 215  PTEHGVDQEDGPEDARPTEHGVDQEDGPEDARPTE 249


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 51/240 (21%), Positives = 96/240 (40%), Gaps = 23/240 (9%)

Query: 857  NASKTADKKLNLGKEDDSSSDSFEN-------LEE-----ESNESGSPFDPVFEVEPKIS 904
            +  +   K + +  +DD   +  EN       LEE      S+E GS  D   E + +  
Sbjct: 1207 SGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTG 1266

Query: 905  NDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVE 964
              N E       P D  E++ +++ + D    E+         L H  + S+ +  +  +
Sbjct: 1267 KQNEEN------PGD-EEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKK 1319

Query: 965  WKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDRE 1024
             K        G   ++VS  +    + +    S+E S+SED +  +  + KKA ++ ++ 
Sbjct: 1320 TKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQR 1379

Query: 1025 QLKWKNSSYG-KVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNMTDG 1083
              K K      KV+       S+ K+ SE +E     + E +    + E+ E  D+ + G
Sbjct: 1380 SYKQKKKRRRIKVQ---EDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPG 1436



 Score = 38.1 bits (87), Expect = 0.046
 Identities = 69/300 (23%), Positives = 121/300 (40%), Gaps = 56/300 (18%)

Query: 733  DDDSDSPSFFEEK---PEEPVVLALDPKGHEDDSYEARKSFLTKYFNKQPYPTRREIEKL 789
            DDD+D  +   +K    E    L+ D  G  DD  E  K    K    +  P   E +  
Sbjct: 1224 DDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGK--QNEENPGDEEAKNQ 1281

Query: 790  AASLWLWKSDIASHFSNK---------RKKCVRDCE-----KYKPGVLLGFNMKELNKVK 835
              S    +SD  S  S K          K  V D E     K KP        +   KV 
Sbjct: 1282 VNS----ESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVS 1337

Query: 836  HEMDFDAEW--------LFENHDEKDSRVNASKTAD------------KKLNLGKEDDSS 875
             E   D+++        + E+ DE+  R  ++K A+            K+  +  ++DSS
Sbjct: 1338 SEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSS 1397

Query: 876  SDSFENLEEESNESGSPFDPVFEVEPKISNDNPEEHVLKVIPEDASESEEKLDQ--KEDG 933
            S++  N EEE  E     +   E E +  ++N +        +   +  +K+ +  K+D 
Sbjct: 1398 SENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDS-------KSPGKGRKKIRKILKDDK 1450

Query: 934  SKYETIHLTEEPTKLMHNASDSEVDQD---DVVEWKDGASPSESGPGSQQVSDFEDNTCE 990
             + ET +  +E  +     ++ E +++   +V+E +D ASP++    ++ V D ++ T E
Sbjct: 1451 LRTETQNALKEEEERRKRIAEREREREKLREVIEIED-ASPTKCPITTKLVLDEDEETKE 1509



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 53/241 (21%), Positives = 94/241 (39%), Gaps = 60/241 (24%)

Query: 851  EKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPEE 910
            EK S+    KT+ KK           D   +  E+S   G   D   + + K      E+
Sbjct: 1005 EKKSKKIRDKTSKKK-----------DELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREK 1053

Query: 911  HVLKVIP------EDASESE-EKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVV 963
               K++       +D S S+ EK   KEDG                 N+SD  + + ++ 
Sbjct: 1054 KRCKLLGKSSRKRQDCSSSDTEKYSMKEDGC----------------NSSDKRLKRIELR 1097

Query: 964  EWKDGASPSESGPGSQQVSDFEDNTCEMKPGTWS---DESSQSEDARSSKPAAKKKATMQ 1020
            E ++ +S              + NT E++ G+ S   +ESS+    +  + ++KKKA + 
Sbjct: 1098 ERRNLSS--------------KRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIV 1143

Query: 1021 GDREQLKWKNSSYGKVEGFWSKDQSQWKNASEN-------DERLSNPQIEWQNSTIDSED 1073
             ++++   + S+  K     S   S  ++  +N       DE+   P  E  N  + S  
Sbjct: 1144 KEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTE--NLVLSSHT 1201

Query: 1074 G 1074
            G
Sbjct: 1202 G 1202



 Score = 30.4 bits (67), Expect = 9.6
 Identities = 49/247 (19%), Positives = 88/247 (35%), Gaps = 44/247 (17%)

Query: 814  DCEKYKPGVLLGFNMKELNKVKHEMDFDAEWLFENHDEKDSRVNASKTADKKLNLGKEDD 873
            D +K K       + K+        ++D+E   E   +  S++ A++T  K++   K+ D
Sbjct: 753  DTKKGKSAKSSIISKKKRQTQSESSNYDSE--LEKEIKSMSKIGAARTTKKRIPNTKDFD 810

Query: 874  SSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPEEHVLKVIPEDASESEEKLDQKEDG 933
            SS D                    E   K   DN     LK   E +S+  E+  ++E  
Sbjct: 811  SSED--------------------EKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETF 850

Query: 934  SKYE--------TIHLTEE-PTKLMHNASDSEVDQ-------------DDVVEWKDGASP 971
            S  E         + L +  P K   +AS   VD+               V E K+ +  
Sbjct: 851  SSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKH 910

Query: 972  SESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDREQLKWKNS 1031
             ++    +      D   +      SDE+S+ +  +S K   +KK      ++ +K +  
Sbjct: 911  LKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQ 970

Query: 1032 SYGKVEG 1038
                 +G
Sbjct: 971  YESSSDG 977


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 51/240 (21%), Positives = 96/240 (40%), Gaps = 23/240 (9%)

Query: 857  NASKTADKKLNLGKEDDSSSDSFEN-------LEE-----ESNESGSPFDPVFEVEPKIS 904
            +  +   K + +  +DD   +  EN       LEE      S+E GS  D   E + +  
Sbjct: 1245 SGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTG 1304

Query: 905  NDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVE 964
              N E       P D  E++ +++ + D    E+         L H  + S+ +  +  +
Sbjct: 1305 KQNEEN------PGD-EEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKK 1357

Query: 965  WKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDRE 1024
             K        G   ++VS  +    + +    S+E S+SED +  +  + KKA ++ ++ 
Sbjct: 1358 TKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQR 1417

Query: 1025 QLKWKNSSYG-KVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNMTDG 1083
              K K      KV+       S+ K+ SE +E     + E +    + E+ E  D+ + G
Sbjct: 1418 SYKQKKKRRRIKVQ---EDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPG 1474



 Score = 38.1 bits (87), Expect = 0.046
 Identities = 69/300 (23%), Positives = 121/300 (40%), Gaps = 56/300 (18%)

Query: 733  DDDSDSPSFFEEK---PEEPVVLALDPKGHEDDSYEARKSFLTKYFNKQPYPTRREIEKL 789
            DDD+D  +   +K    E    L+ D  G  DD  E  K    K    +  P   E +  
Sbjct: 1262 DDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGK--QNEENPGDEEAKNQ 1319

Query: 790  AASLWLWKSDIASHFSNK---------RKKCVRDCE-----KYKPGVLLGFNMKELNKVK 835
              S    +SD  S  S K          K  V D E     K KP        +   KV 
Sbjct: 1320 VNS----ESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVS 1375

Query: 836  HEMDFDAEW--------LFENHDEKDSRVNASKTAD------------KKLNLGKEDDSS 875
             E   D+++        + E+ DE+  R  ++K A+            K+  +  ++DSS
Sbjct: 1376 SEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSS 1435

Query: 876  SDSFENLEEESNESGSPFDPVFEVEPKISNDNPEEHVLKVIPEDASESEEKLDQ--KEDG 933
            S++  N EEE  E     +   E E +  ++N +        +   +  +K+ +  K+D 
Sbjct: 1436 SENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDS-------KSPGKGRKKIRKILKDDK 1488

Query: 934  SKYETIHLTEEPTKLMHNASDSEVDQD---DVVEWKDGASPSESGPGSQQVSDFEDNTCE 990
             + ET +  +E  +     ++ E +++   +V+E +D ASP++    ++ V D ++ T E
Sbjct: 1489 LRTETQNALKEEEERRKRIAEREREREKLREVIEIED-ASPTKCPITTKLVLDEDEETKE 1547



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 53/241 (21%), Positives = 94/241 (39%), Gaps = 60/241 (24%)

Query: 851  EKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPEE 910
            EK S+    KT+ KK           D   +  E+S   G   D   + + K      E+
Sbjct: 1043 EKKSKKIRDKTSKKK-----------DELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREK 1091

Query: 911  HVLKVIP------EDASESE-EKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVV 963
               K++       +D S S+ EK   KEDG                 N+SD  + + ++ 
Sbjct: 1092 KRCKLLGKSSRKRQDCSSSDTEKYSMKEDGC----------------NSSDKRLKRIELR 1135

Query: 964  EWKDGASPSESGPGSQQVSDFEDNTCEMKPGTWS---DESSQSEDARSSKPAAKKKATMQ 1020
            E ++ +S              + NT E++ G+ S   +ESS+    +  + ++KKKA + 
Sbjct: 1136 ERRNLSS--------------KRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIV 1181

Query: 1021 GDREQLKWKNSSYGKVEGFWSKDQSQWKNASEN-------DERLSNPQIEWQNSTIDSED 1073
             ++++   + S+  K     S   S  ++  +N       DE+   P  E  N  + S  
Sbjct: 1182 KEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTE--NLVLSSHT 1239

Query: 1074 G 1074
            G
Sbjct: 1240 G 1240



 Score = 30.4 bits (67), Expect = 9.6
 Identities = 49/247 (19%), Positives = 88/247 (35%), Gaps = 44/247 (17%)

Query: 814  DCEKYKPGVLLGFNMKELNKVKHEMDFDAEWLFENHDEKDSRVNASKTADKKLNLGKEDD 873
            D +K K       + K+        ++D+E   E   +  S++ A++T  K++   K+ D
Sbjct: 791  DTKKGKSAKSSIISKKKRQTQSESSNYDSE--LEKEIKSMSKIGAARTTKKRIPNTKDFD 848

Query: 874  SSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPEEHVLKVIPEDASESEEKLDQKEDG 933
            SS D                    E   K   DN     LK   E +S+  E+  ++E  
Sbjct: 849  SSED--------------------EKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETF 888

Query: 934  SKYE--------TIHLTEE-PTKLMHNASDSEVDQ-------------DDVVEWKDGASP 971
            S  E         + L +  P K   +AS   VD+               V E K+ +  
Sbjct: 889  SSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKH 948

Query: 972  SESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDREQLKWKNS 1031
             ++    +      D   +      SDE+S+ +  +S K   +KK      ++ +K +  
Sbjct: 949  LKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQ 1008

Query: 1032 SYGKVEG 1038
                 +G
Sbjct: 1009 YESSSDG 1015


>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
          Length = 2382

 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 52/173 (30%), Positives = 73/173 (42%), Gaps = 38/173 (21%)

Query: 285 PRIGSLASGNVRS-----------LPSQQMVNRLSIPKPNLNSTGV---NMMSSVHLQQN 330
           P I  L+ G V S           + SQQ V+  S      +STG    ++ S+V  Q  
Sbjct: 645 PSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGS-QHEQAHSTGTVPGHIPSTVQAQSQ 703

Query: 331 NYGV---KSVGQGYSVGQ---SMRLGLGGNAPVSIPQQSQSVKQLLPSGNGRSYGLGSEQ 384
            +GV    SV QG S GQ   S   G+  + P+  PQQ Q ++Q  P             
Sbjct: 704 PHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAP------------- 750

Query: 385 RSQAPARYSLQSANASSLSSGQLKSPSLSQSQASRVLGQSSSKPAAAATGPPP 437
             Q   +YSL   + +S SS    +  +SQ QA +VL Q S+      + P P
Sbjct: 751 -PQQTVQYSL---SQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVP 799


>gi|169213233 PREDICTED: similar to hCG1654128 [Homo sapiens]
          Length = 1070

 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 42/160 (26%), Positives = 69/160 (43%), Gaps = 18/160 (11%)

Query: 869  GKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPEEHVL---KVIPEDASESEE 925
            G ED S ++   + +E+  E  SP +     E    + +P EH +   +  PEDA  +E 
Sbjct: 293  GPEDASPTEHGVDQQEDGPEDASPTEHGVNQEDGPEDASPTEHGVDQQEDGPEDARPTEH 352

Query: 926  KLDQKEDGSKYETI--HLTEEPTKLMHNASDSEVDQDDVVEWKDGASPSESG-------- 975
             +DQ+EDG +  ++  H  ++      +AS +E   D   +  + ASP+E G        
Sbjct: 353  GIDQEEDGPEDASLTEHGVDQQEDGPEDASPTEHGIDQEEDGPEDASPTEHGVDQEEDGP 412

Query: 976  ----PGSQQVSDFEDNTCEMKPGTWS-DESSQSEDARSSK 1010
                P    V   ED   +  P     D+    EDAR ++
Sbjct: 413  EDASPTEHGVDQEEDGPEDASPTEHGVDQEDGPEDARPTE 452



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 43/153 (28%), Positives = 67/153 (43%), Gaps = 21/153 (13%)

Query: 869  GKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPEEHVLKVI--------PEDA 920
            G ED S ++   + +E+  E   P +   + E     D PE+  L           PEDA
Sbjct: 326  GPEDASPTEHGVDQQEDGPEDARPTEHGIDQE----EDGPEDASLTEHGVDQQEDGPEDA 381

Query: 921  SESEEKLDQKEDGSK--YETIHLTEEPTKLMHNASDSEVDQDDVVEWKDGASPSESGPGS 978
            S +E  +DQ+EDG +    T H  ++      +AS +E   D   +  + ASP+E G   
Sbjct: 382  SPTEHGIDQEEDGPEDASPTEHGVDQEEDGPEDASPTEHGVDQEEDGPEDASPTEHG--- 438

Query: 979  QQVSDFEDNTCEMKPGTWS-DESSQSEDARSSK 1010
                D ED   + +P     D+    EDAR ++
Sbjct: 439  ---VDQEDGPEDARPTEHGVDQEDGPEDARPTE 468


>gi|169212742 PREDICTED: similar to hCG1654128 [Homo sapiens]
          Length = 1015

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 46/171 (26%), Positives = 74/171 (43%), Gaps = 33/171 (19%)

Query: 851  EKDSRVNASKT---ADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDN 907
            E+D   +AS T    D++ + G ED S ++   + +E+  E   P +   + E     D 
Sbjct: 249  EEDGPEDASPTEHGVDQQED-GPEDASPTEHGVDQQEDGPEDARPTEHGVDQE----EDG 303

Query: 908  PEEHVLKVI--------PEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQ 959
            PE+  L           PEDAS +E  +DQ+EDG +               +AS +E   
Sbjct: 304  PEDASLTEHGVDQQEDGPEDASPTEHGIDQEEDGPE---------------DASPTEHGV 348

Query: 960  DDVVEWKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSK 1010
            D   +  + ASP+E   G  Q  D  ++    + G   D+    EDAR ++
Sbjct: 349  DQEEDGPEDASPTEHEHGVDQEEDGPEDASPTEHGV--DQEDGPEDARPTE 397



 Score = 31.6 bits (70), Expect = 4.3
 Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 8/60 (13%)

Query: 917 PEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKDGASPSESGP 976
           PEDAS +E  + Q+EDG         E+ +   H     E   +D    + G    E GP
Sbjct: 236 PEDASPTEHDVGQEEDG--------PEDASPTEHGVDQQEDGPEDASPTEHGVDQQEDGP 287


>gi|109452595 zinc finger protein 205 [Homo sapiens]
          Length = 554

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 46/189 (24%), Positives = 72/189 (38%), Gaps = 29/189 (15%)

Query: 385 RSQAPARYSLQSANASSLSSGQLKSPSLSQSQASRVLGQSSSK----PAAAATGPPPGNT 440
           RS  PA+ S Q A            PS ++ Q  RV  + + +    P +   G  P + 
Sbjct: 243 RSSGPAKDSGQPAEPDRTPDAAPPDPSPTEPQEYRVPEKPNEEEKGAPESGEEGLAPDSE 302

Query: 441 SSTQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCN-RYLP 499
              + ++ C  C + F  + + V   + H  EK  A              C  C  R+  
Sbjct: 303 VGRKSYR-CEQCGKGFSWHSHLVTHRRTHTGEKPYA--------------CTDCGKRFGR 347

Query: 500 TDTLLNHMLIHG----LSCPYCRSTFNDVEKMAAHMRMVHIDEEMGPKTDSTLSF----D 551
           +  L+ H +IH      +CP CR +F+    +  H R +H  E+          F    D
Sbjct: 348 SSHLIQHQIIHTGEKPYTCPACRKSFSHHSTLIQHQR-IHTGEKPYVCDRCAKRFTRRSD 406

Query: 552 LTLQQGSHT 560
           L   QG+HT
Sbjct: 407 LVTHQGTHT 415


>gi|109452593 zinc finger protein 205 [Homo sapiens]
          Length = 554

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 46/189 (24%), Positives = 72/189 (38%), Gaps = 29/189 (15%)

Query: 385 RSQAPARYSLQSANASSLSSGQLKSPSLSQSQASRVLGQSSSK----PAAAATGPPPGNT 440
           RS  PA+ S Q A            PS ++ Q  RV  + + +    P +   G  P + 
Sbjct: 243 RSSGPAKDSGQPAEPDRTPDAAPPDPSPTEPQEYRVPEKPNEEEKGAPESGEEGLAPDSE 302

Query: 441 SSTQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCN-RYLP 499
              + ++ C  C + F  + + V   + H  EK  A              C  C  R+  
Sbjct: 303 VGRKSYR-CEQCGKGFSWHSHLVTHRRTHTGEKPYA--------------CTDCGKRFGR 347

Query: 500 TDTLLNHMLIHG----LSCPYCRSTFNDVEKMAAHMRMVHIDEEMGPKTDSTLSF----D 551
           +  L+ H +IH      +CP CR +F+    +  H R +H  E+          F    D
Sbjct: 348 SSHLIQHQIIHTGEKPYTCPACRKSFSHHSTLIQHQR-IHTGEKPYVCDRCAKRFTRRSD 406

Query: 552 LTLQQGSHT 560
           L   QG+HT
Sbjct: 407 LVTHQGTHT 415


>gi|197382841 zinc finger protein 485 [Homo sapiens]
          Length = 441

 Score = 41.2 bits (95), Expect = 0.005
 Identities = 39/177 (22%), Positives = 65/177 (36%), Gaps = 20/177 (11%)

Query: 406 QLKSPSLSQSQASRVLGQSSSKPAAAATGPPPGNTSSTQKWKICTICNELFPENVYSVHF 465
           + K  +L QS +   +    +K      G      SST+K   C  C ++F  N   +  
Sbjct: 89  ETKMSALKQSTSEASVLGERTKSVMMEKGLDWEGRSSTEKNYKCKECGKVFKYNSSFISH 148

Query: 466 EKEHKAEKVPAVANYIMKIHNFTS--------------KCLYCNRYLPT-DTLLNHMLIH 510
           ++ H +EK        +   N +S              +C+ C ++L    T +NH  IH
Sbjct: 149 QRNHTSEKPHKCKECGIAFMNSSSLLNHHKVHAGKQPYRCIECGKFLKKHSTFINHQRIH 208

Query: 511 GLSCPY----CRSTFNDVEKMAAHMRMVHIDEEMGPKTDSTLSFDLTLQQGSHTNIH 563
               P+    C  TF     + +H R +H  ++     D   +F        H  IH
Sbjct: 209 SREKPHKCIECGKTFRKNSILLSHQR-IHTGQKPYKCNDCGKAFAQNAALTRHERIH 264


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 41.2 bits (95), Expect = 0.005
 Identities = 47/194 (24%), Positives = 79/194 (40%), Gaps = 20/194 (10%)

Query: 853  DSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPEEHV 912
            D    +S ++D++ N  + ++   +     +EE  E     + V E   +   +  EE  
Sbjct: 182  DHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEE 241

Query: 913  LKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKDGASPS 972
             +   E+  E +E+ DQKE+G+ Y+T             ASDS     + V + DG+  S
Sbjct: 242  EEEEEEEEYEQDER-DQKEEGNDYDT----------RSEASDS---GSESVSFTDGSVRS 287

Query: 973  ESG-PGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDR----EQLK 1027
             SG  GS +          + P  + D S  S     +   +K K  +Q  R    +   
Sbjct: 288  GSGTDGSDEKKKERKRARGISPIVF-DRSGSSASESYADQTSKLKYVLQDARFFLIKSNN 346

Query: 1028 WKNSSYGKVEGFWS 1041
             +N S  K +G WS
Sbjct: 347  HENVSLAKAKGVWS 360


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
            sapiens]
          Length = 699

 Score = 40.8 bits (94), Expect = 0.007
 Identities = 49/200 (24%), Positives = 80/200 (40%), Gaps = 21/200 (10%)

Query: 856  VNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPEEHVLKV 915
            V A+ T  +K +    +DSSSD  E  ++       P+  V    P  S   P++ +   
Sbjct: 254  VKAATTPTRKSS--SSEDSSSDEEEEQKKPMKNKPGPYSSV----PPPSAPPPKKSLGTQ 307

Query: 916  IPEDASESEEKLDQKEDGSKYETIHLTEE---PTKLMHNASDSEVDQDDVVEWKDGASPS 972
             P+ A E ++ ++  ED S        EE   PTK + + + ++               +
Sbjct: 308  PPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPP--------AKKAA 359

Query: 973  ESGPGSQQVSDFEDNTCEMKP-GTWSDESSQSEDARSS---KPAAKKKATMQGDREQLKW 1028
            ES   S      ED+    KP GT  + S++      S   KPAA  K  + G ++ L  
Sbjct: 360  ESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTR 419

Query: 1029 KNSSYGKVEGFWSKDQSQWK 1048
            K  S    E   S ++ + K
Sbjct: 420  KADSSSSEEESSSSEEEKTK 439



 Score = 34.3 bits (77), Expect = 0.67
 Identities = 48/198 (24%), Positives = 76/198 (38%), Gaps = 21/198 (10%)

Query: 838  MDFDAEWLFENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVF 897
            +D  + WL ++    + ++ A+    KK    K+  SSSDS ++ EEE    G P     
Sbjct: 51   LDIYSFWL-KSAKVPERKLQANGPVAKK---AKKKASSSDSEDSSEEEEEVQGPPAKKA- 105

Query: 898  EVEPKISNDNPEEHVLKVIPEDASESEEKLDQKED--------GSKYETIHLTEEPTKLM 949
             V  K     P +   K     +SE     D +ED        G K +       P K  
Sbjct: 106  AVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAK 165

Query: 950  HNASDSEVDQDD--VVEWKDGASP------SESGPGSQQVSDFEDNTCEMKPGTWSDESS 1001
             + SDS+   +D      K   +P      +++ P   + +    N       + S  SS
Sbjct: 166  SSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSS 225

Query: 1002 QSEDARSSKPAAKKKATM 1019
             S+D+   K AA  K T+
Sbjct: 226  SSDDSEEEKAAATPKKTV 243



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 36/161 (22%), Positives = 62/161 (38%), Gaps = 17/161 (10%)

Query: 872  DDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPEEHVLKVIPEDAS-ESEEKLDQK 930
            + SSS+   + ++E ++   P     + + K +   P++        D+S E E   +QK
Sbjct: 125  ESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQK 184

Query: 931  EDGSKYETIHLTEEPTKLMHNA--------------SDSEVDQDDVVEWKDGASPSESGP 976
               +       T+ P K    A              S S    DD  E K  A+P ++ P
Sbjct: 185  PKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVP 244

Query: 977  GSQQV--SDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKK 1015
              Q V  +  +  T   +  + S++SS  E+    KP   K
Sbjct: 245  KKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNK 285


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
            [Homo sapiens]
          Length = 651

 Score = 40.8 bits (94), Expect = 0.007
 Identities = 58/298 (19%), Positives = 125/298 (41%), Gaps = 30/298 (10%)

Query: 797  KSDIASHFSNKRKKCVRDCEKYKPG------VLLGFNMKELNKVKHEMDFDAEWLF-ENH 849
            K+ + S   N++ K  +   +  P       V    + K+    K+    + E+L  +N+
Sbjct: 160  KTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNN 219

Query: 850  DEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPE 909
             +KD  +  SKT++  ++    ++S +  F  L  +S++    FD         S +N +
Sbjct: 220  PKKD--LKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLR---NYSQNNSK 274

Query: 910  EHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKDGA 969
             + LK       ++++   +  D    ++    ++  K+  N    +  +D  V+    +
Sbjct: 275  NYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKD--VKKDTES 332

Query: 970  SPSESGPGSQQVSDFEDNTCEMK-----------PGTWSDESSQSEDARSSK---PAAKK 1015
            + +ESG    +  D + +  ++K           P +   ES  ++DAR+       A K
Sbjct: 333  TDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASK 392

Query: 1016 KATMQGDREQLKWKNSSYGKVEGFWS-KDQSQWKNASENDERLSNPQIEWQNSTIDSE 1072
                + D +++ +   S  ++E   S KD+ + K  S+ D + S    E +++  DSE
Sbjct: 393  NDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDE-ESTDADSE 449



 Score = 38.5 bits (88), Expect = 0.035
 Identities = 45/230 (19%), Positives = 98/230 (42%), Gaps = 43/230 (18%)

Query: 847  ENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISND 906
            E+ D KD++ ++ K    K N+ K+DD   D  ++ E    ESG               D
Sbjct: 299  ESEDSKDAKKDSKKV---KKNV-KKDDKKKDVKKDTESTDAESG---------------D 339

Query: 907  NPEEHVLKVIPEDASESEEKL---DQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVV 963
            + +E       +D  + ++KL   D+K+D  KY        P      + D++  ++D  
Sbjct: 340  SKDER------KDTKKDKKKLKKDDKKKDTKKY--------PESTDTESGDAKDARNDSR 385

Query: 964  EWKDGASPSESGPGSQQVSDFEDNTCEMK-PGTWSDESSQSEDARSSKPAAKKKATMQGD 1022
              K  +   +    +++++   D+  E++   +  DE    +D+++    + K      D
Sbjct: 386  NLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTD 445

Query: 1023 REQLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSE 1072
             +     +S  GK      KD+ + K  S+ D++  + +   +++ ++S+
Sbjct: 446  ADSEPKGDSKKGK------KDEKKGKKDSKKDDKKKDAKKNAESTEMESD 489



 Score = 35.4 bits (80), Expect = 0.30
 Identities = 67/311 (21%), Positives = 121/311 (38%), Gaps = 48/311 (15%)

Query: 761  DDSYEARKSFLTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKP 820
            +DS +A+K       N +    +++++K   S     +D  S  S   +K   D +K K 
Sbjct: 301  EDSKDAKKDSKKVKKNVKKDDKKKDVKKDTES-----TDAESGDSKDERK---DTKKDKK 352

Query: 821  GVLLGFNMKELNKVKHEMDFDAEWLFENHDEKDSRVNASKTADKKLNLGK---EDDSSSD 877
             +      K+  K     D ++    +  ++  +   ASK  DKK +  K     DS S+
Sbjct: 353  KLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESE 412

Query: 878  SFENLEEESNESGSPFDPVFEVEPKISNDNPEEHVLKVIPEDA-----SESEEKLDQKED 932
              E+ E + +E     D   + +  + ND            D+      E + K D K+D
Sbjct: 413  -LESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKD 471

Query: 933  GSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKDGASPSESGPGSQQVSDFEDNTCEMK 992
              K +             NA  +E++ D  +E K     S+   GS++         ++K
Sbjct: 472  DKKKDA----------KKNAESTEMESD--LELKKDKKHSKEKKGSKK---------DIK 510

Query: 993  PGTWSD-ESSQSEDARSSKPAAKKKATMQG---DREQLKWKNSSYGKVEGFWSKDQSQWK 1048
                 D ES+ +E   SSK   K    ++G   + E+  +K  +  K+      D+S   
Sbjct: 511  KDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKI------DESDGT 564

Query: 1049 NASENDERLSN 1059
            +A+   E L +
Sbjct: 565  SANSKMEGLES 575



 Score = 31.2 bits (69), Expect = 5.7
 Identities = 40/207 (19%), Positives = 80/207 (38%), Gaps = 30/207 (14%)

Query: 904  SNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVV 963
            S  NPE    K + ++ S+ ++K  +    +  E +H    P K +  +  S     ++ 
Sbjct: 179  SETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEIC 238

Query: 964  EWKD---------GASPSESGPGSQQVSDFEDNTC-------------EMKPGTWSDESS 1001
                         G S  ES      + ++  N               + K        +
Sbjct: 239  SENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDA 298

Query: 1002 QSEDARSSKPAAK--KKATMQGDREQLKWKNSSYGKVEGFWSKDQ----SQWKNASENDE 1055
            +SED++ +K  +K  KK   + D+++   K++     E   SKD+     + K   + D+
Sbjct: 299  ESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDD 358

Query: 1056 RLSNPQIEWQNSTIDSEDGEQFDNMTD 1082
            +  + + ++  ST D+E G+  D   D
Sbjct: 359  KKKDTK-KYPEST-DTESGDAKDARND 383


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 40.8 bits (94), Expect = 0.007
 Identities = 70/333 (21%), Positives = 134/333 (40%), Gaps = 51/333 (15%)

Query: 711  SLAPVKRTYEQMEFPLLKKRKLDDDSDSPSFFEEKPEEPVVLALDPKGHEDDSYEARKSF 770
            SL PV++  E  +   L ++K    S +     +  +E  V+      H+  + E  +  
Sbjct: 588  SLKPVRKRQEHRKRASLSEKKSPFLSSAEGAVPKLDKEGKVVKKHKTKHKHKNKEKGQCS 647

Query: 771  LTKYFNKQPYPTRREIEKLAAS-LWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMK 829
            +++    + +    E  K  +    L ++D+++   NK K    D + +K         +
Sbjct: 648  ISQELKLKSFTYEYEDSKQKSDKAILLENDLSTE--NKLKVLKHDRDHFK-------KEE 698

Query: 830  ELNKVKHEMDFDAEWLFENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNES 889
            +L+K+K E   + EWLF+  DEK              +L +  D++ D   +  EE + S
Sbjct: 699  KLSKMKLE---EKEWLFK--DEK--------------SLKRIKDTNKDISRSFREEKDRS 739

Query: 890  GSPFDPVFEVEPKISNDNPEEHVLKVIPED--------ASESEEKLDQKEDG-SKYETIH 940
                    E E  +   +P+E  L++  E+         S+ E+K D KED  SK +   
Sbjct: 740  NKA-----EKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKEDKISKEKEKI 794

Query: 941  LTEEPTKLM-------HNASDSEVDQDDVVEWKDGASPSESGPGSQQVSDFEDNTCEMK- 992
              E+  KL         +A D   +++  +E +D           +  SD  D++ + K 
Sbjct: 795  FKEDKEKLKKEKVYREDSAFDEYCNKNQFLENEDTKFSLSDDQRDRWFSDLSDSSFDFKG 854

Query: 993  PGTWSDESSQSEDARSSKPAAKKKATMQGDREQ 1025
              +W    +   D +S   A     T++ D ++
Sbjct: 855  EDSWDSPVTDYRDMKSDSVAKLILETVKEDSKE 887



 Score = 31.2 bits (69), Expect = 5.7
 Identities = 49/253 (19%), Positives = 95/253 (37%), Gaps = 26/253 (10%)

Query: 797  KSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDFDAEWLFENHDEKDSRV 856
            KS    H   ++ K  RD  K +     G + KE              +FE H EK  + 
Sbjct: 1166 KSSDKQHPERQKDKEPRDRRKDRGAADAGRDKKEK-------------VFEKHKEKKDKE 1212

Query: 857  NASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPEEHVLKVI 916
            +  K  D+K     +      + + L E++ +  +  D   + + K    + +EH  +  
Sbjct: 1213 STEKYKDRKDRASVDSTQDKKNKQKLPEKAEKKHAAED---KAKSKHKEKSDKEHSKERK 1269

Query: 917  PEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKDGASPSESGP 976
               ++++E+ L +K    + E +H   E +    N   SEV  D   +   G  P  +  
Sbjct: 1270 SSRSADAEKSLLEK---LEEEALHEYREDS----NDKISEVSSDSFTD--RGQEPGLTAF 1320

Query: 977  GSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQ-GDREQLKWKNSSYGK 1035
                 ++   +    +     ++  + E  R S  ++KK    +   +E+ + K      
Sbjct: 1321 LEVSFTEPPGDDKPRESACLPEKLKEKERHRHSSSSSKKSHDRERAKKEKAEKKEKGEDY 1380

Query: 1036 VEGFWSKDQSQWK 1048
             EG   KD  Q++
Sbjct: 1381 KEGGSRKDSGQYE 1393


>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
            [Homo sapiens]
          Length = 666

 Score = 40.8 bits (94), Expect = 0.007
 Identities = 61/245 (24%), Positives = 92/245 (37%), Gaps = 30/245 (12%)

Query: 870  KEDDSSSDSF---ENLEEESNESGSPFDPVFEVEPKISNDNPEEHVLKVIPEDASESE-- 924
            K+ DS SDS    EN    SN SGS  D   + E   S     + +     ED   S   
Sbjct: 19   KDSDSGSDSDSDQENAASGSNASGSESD---QDERGDSGQPSNKELFGDDSEDEGASHHS 75

Query: 925  ------EKLDQKEDGSKYETIHLTEEPTKL-MHNASDSEVDQDDVVEWKDGASPSESGPG 977
                  E+ D + + S+  + H   +P+ +  H+ S++  D +D     DG S      G
Sbjct: 76   GSDNHSERSDNRSEASE-RSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEG 134

Query: 978  SQQV-SDFEDNTCEMKPGTWSDESSQSED------------ARSSKPAAKKKATMQGDRE 1024
            S++  SD E    E K     DE  Q+ D             ++S    K + T   +R 
Sbjct: 135  SEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERP 194

Query: 1025 QLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNMTDGV 1084
            QL          E   + D  +   AS+ND+   N   E Q    D E  +  D+     
Sbjct: 195  QLSDDERQQLSEEEKANSDDER-PVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQA 253

Query: 1085 AEPMH 1089
            ++  H
Sbjct: 254  SDEEH 258



 Score = 37.7 bits (86), Expect = 0.060
 Identities = 35/182 (19%), Positives = 70/182 (38%), Gaps = 17/182 (9%)

Query: 848  NHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPV--FEVEPKISN 905
            +H E +    A    +K     K D S  +  +N ++E    GS  D +   + + K+ N
Sbjct: 128  HHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQN 187

Query: 906  DNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQ---DDV 962
             + EE      P+ + +  ++L ++E  +  +   +  +      N+ D E  Q   ++ 
Sbjct: 188  TDDEER-----PQLSDDERQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQPQLSDEEK 242

Query: 963  VEWKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGD 1022
            ++  D   P  S    +   D E+            ES++  D+       K+K  +  D
Sbjct: 243  MQNSDDERPQASDEEHRHSDDEEEQ-------DHKSESARGSDSEDEVLRMKRKNAIASD 295

Query: 1023 RE 1024
             E
Sbjct: 296  SE 297



 Score = 35.0 bits (79), Expect = 0.39
 Identities = 53/221 (23%), Positives = 86/221 (38%), Gaps = 34/221 (15%)

Query: 847  ENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISND 906
            E  +  D R  AS   D+K N   E+       E ++   +E            P+ S+ 
Sbjct: 208  EKANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDE-----------RPQASD- 255

Query: 907  NPEEHVLKVIPEDASESEEKLDQKED---GSKYETIHLTEEPTKLMHNASDSEVDQDDVV 963
              EEH         S+ EE+ D K +   GS  E   L  +    +  ASDSE D D  V
Sbjct: 256  --EEH-------RHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAI--ASDSEADSDTEV 304

Query: 964  EWKDGASPSESGPGSQQVSDFEDNTCE-MKPGTWSDESSQSEDARSSKPAAKKKATMQGD 1022
              KD +   +   G+  +S   D   +   PG   DE+   +D +  +P  + +  ++  
Sbjct: 305  P-KDNSGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEEPIPETRIEVEIP 363

Query: 1023 REQLKWKNSSY-GKVEGFWSK-----DQSQWKNASENDERL 1057
            +      N  Y  K+  F S      D   +++  E++E L
Sbjct: 364  KVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEML 404


>gi|24415404 MDN1, midasin homolog [Homo sapiens]
          Length = 5596

 Score = 40.8 bits (94), Expect = 0.007
 Identities = 52/258 (20%), Positives = 104/258 (40%), Gaps = 27/258 (10%)

Query: 852  KDSRVNASKTADKKLNLGK-----EDDSSSDSFENLEEESNESGSPFDPVFEVEPKISND 906
            +D+ +  S+  D K++ G+     EDD  SDS E  + + +      +   +++ ++  D
Sbjct: 4723 EDNAIEMSEDFDGKMHDGELEEQEEDDEKSDS-EGGDLDKHMGDLNGEEADKLDERLWGD 4781

Query: 907  NPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWK 966
            + EE       ED  E + K ++   G   E   L  +   L    S+ +  Q D  E K
Sbjct: 4782 DDEE-------EDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEK 4834

Query: 967  DGASPSESGPGSQQVS------DFEDNTCEMKPGTWSDESSQSEDARS-----SKPAAKK 1015
            + A   + G G  +++      D+++N  E+ P   + E     +A       +  +  K
Sbjct: 4835 EEAEADDGGQGEDKINEQIDERDYDEN--EVDPYHGNQEKVPEPEALDLPDDLNLDSEDK 4892

Query: 1016 KATMQGDREQLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGE 1075
                  D E+ + +N    K +   +  +++ +  +E D+  S    E +    + +  E
Sbjct: 4893 NGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAE 4952

Query: 1076 QFDNMTDGVAEPMHGSLA 1093
              + M  G A+   G  A
Sbjct: 4953 GEEEMDTG-ADDQDGDAA 4969



 Score = 34.7 bits (78), Expect = 0.51
 Identities = 37/174 (21%), Positives = 74/174 (42%), Gaps = 16/174 (9%)

Query: 830  ELNKVKHEMDFDAEWL--FENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFEN------ 881
            ++N+   E D+D   +  +  + EK     A    D  LNL  ED +  +  +N      
Sbjct: 4848 KINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDD-LNLDSEDKNGGEDTDNEEGEEE 4906

Query: 882  ----LEEESNESGSPFDPVFEVEP-KISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKY 936
                ++E+  E+G   +   E E  +  + +P+E       +D +E EE++D   D    
Sbjct: 4907 NPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDG 4966

Query: 937  ETIHLTEEPTKLMHNASDSEVDQDDVVEWKDGASPSESGPGSQQVSDFEDNTCE 990
            +     EE ++    + + +  + D    ++G  P++ G   Q+  + ED+  E
Sbjct: 4967 DAAQHPEEHSEEQQQSVEEKDKEADEEGGENG--PADQGFQPQEEEEREDSDTE 5018


>gi|61743930 zinc finger and BTB domain containing 41 [Homo sapiens]
          Length = 909

 Score = 40.4 bits (93), Expect = 0.009
 Identities = 36/110 (32%), Positives = 47/110 (42%), Gaps = 10/110 (9%)

Query: 72  KPFCCSACPFSSKFFSAYKSHFRNVHSEDFE-NRILLNCPYCT-FNADKKTLETHIKIFH 129
           KPF C  C       S    H R  HS + E ++    CPYC   +A KKTL  H+K FH
Sbjct: 387 KPFECDICHQRYSTKSNLTVH-RKKHSNETEFHKKEHKCPYCNKLHASKKTLAKHVKRFH 445

Query: 130 APNASAPSSSLSTFKDKNKNDGLK---PKQADSVEQAVYYCK----KCTY 172
             NA    S   T  +  K D  K    ++    E  + + +    KCTY
Sbjct: 446 PENAQEFISIKKTKSESWKCDICKKSFTRRPHLEEHMILHSQDKPFKCTY 495



 Score = 38.5 bits (88), Expect = 0.035
 Identities = 28/102 (27%), Positives = 46/102 (45%), Gaps = 25/102 (24%)

Query: 444 QKWKI----CTICNELFP-ENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCNR-Y 497
           QK+K     C +C ++F  ++   +HF + H  EK                KC  CN+ +
Sbjct: 661 QKYKATFHQCDVCKKIFKGKSSLEMHF-RTHSGEK--------------PYKCQICNQSF 705

Query: 498 LPTDTLLNHMLIHG----LSCPYCRSTFNDVEKMAAHMRMVH 535
               TL  H++IH      +C +C +TF   +K+  H+  VH
Sbjct: 706 RIKKTLTKHLVIHSDARPFNCQHCNATFKRKDKLKYHIDHVH 747


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 40.4 bits (93), Expect = 0.009
 Identities = 47/211 (22%), Positives = 84/211 (39%), Gaps = 36/211 (17%)

Query: 853  DSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPEEHV 912
            D    +S ++D++ N  + ++   +     +EE  E     + V E   +   +  EE  
Sbjct: 182  DHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEE 241

Query: 913  LKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKDGASPS 972
             +   E+  E +E+ DQKE+G+ Y+T             ASDS     + V + DG+  S
Sbjct: 242  EEEEEEEEYEQDER-DQKEEGNDYDT----------RSEASDS---GSESVSFTDGSVRS 287

Query: 973  ESG-PGSQQVSDFEDNTCEMKP------GTWSDESSQSEDARSSKPAAKKKATMQGDREQ 1025
             SG  GS +          + P      G+ + ES    + +  K ++  +A  +    +
Sbjct: 288  GSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSK 347

Query: 1026 LKW---------------KNSSYGKVEGFWS 1041
            LK+               +N S  K +G WS
Sbjct: 348  LKYVLQDARFFLIKSNNHENVSLAKAKGVWS 378


>gi|16445033 ACRC protein [Homo sapiens]
          Length = 691

 Score = 40.0 bits (92), Expect = 0.012
 Identities = 36/172 (20%), Positives = 75/172 (43%), Gaps = 7/172 (4%)

Query: 847  ENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISND 906
            ++ +  D   + S+  D   +  +  D +SD  E  ++ S++S  P D   +     S+D
Sbjct: 144  DDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDD 203

Query: 907  NPEEHV-LKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEW 965
            + +++     +P+D S+  +  D   D S  +    + + ++   ++SD     DD  + 
Sbjct: 204  SSDDNSDDSDVPDDKSDDSDVPDDSSDDS--DVPDDSSDDSEAPDDSSDDSEAPDDSSD- 260

Query: 966  KDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKA 1017
             D  +P +S   S+   D  D++        SD+S  S+D+     A   K+
Sbjct: 261  -DSEAPDDSSDDSEAPDDSSDDSEASDDS--SDDSEASDDSSDDSEAPDDKS 309


>gi|40806227 zinc finger protein 64 isoform c [Homo sapiens]
          Length = 679

 Score = 39.7 bits (91), Expect = 0.016
 Identities = 43/179 (24%), Positives = 77/179 (43%), Gaps = 18/179 (10%)

Query: 72  KPFCCSACPFSSKFFSAYKSHFRNVHSED--FENRILLNCPYCTFNADKKTLETHIKIFH 129
           KP+ C  C +++   S+   H R +HS++  F+ +I   CPY + N+ + T+        
Sbjct: 199 KPYKCKTCDYAAADSSSLNKHLR-IHSDERPFKCQI---CPYASRNSSQLTVHLRSHTGD 254

Query: 130 APNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHF 189
           AP        L + K K  +D  +  +  S E+  + C+ C  R  +   ++ HI  +H 
Sbjct: 255 APF----QCWLCSAKFKISSDLKRHMRVHSGEKP-FKCEFCNVRCTMKGNLKSHIRIKHS 309

Query: 190 -QHVAAPYIAKAGEKSLNGAVPLGSNAREESSIHCKRCLFMPKSYEALVQHVIEDHERI 247
             +   P+    G+        L  ++R   S H ++C     SY    +  +  HERI
Sbjct: 310 GNNFKCPHCDFLGDSK----ATLRKHSRVHQSEHPEKC--SECSYSCSSKAALRIHERI 362



 Score = 37.7 bits (86), Expect = 0.060
 Identities = 39/161 (24%), Positives = 57/161 (35%), Gaps = 21/161 (13%)

Query: 72  KPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKK-TLETHIKIF-- 128
           KPF C  C          KSH R  HS +        CP+C F  D K TL  H ++   
Sbjct: 283 KPFKCEFCNVRCTMKGNLKSHIRIKHSGN-----NFKCPHCDFLGDSKATLRKHSRVHQS 337

Query: 129 -HAPNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYRE 187
            H    S  S S S+         L+  +        + C  C++       + KH+ + 
Sbjct: 338 EHPEKCSECSYSCSS------KAALRIHERIHCTDRPFKCNYCSFDTKQPSNLSKHMKKF 391

Query: 188 HFQHVAAPYIAK--AGEKSLNGAVPLGSNAREESSIHCKRC 226
           H   V    + +   G +S      L +    + S HC  C
Sbjct: 392 HGDMVKTEALERKDTGRQSSRQVAKLDA----KKSFHCDIC 428


>gi|40806225 zinc finger protein 64 isoform b [Homo sapiens]
          Length = 627

 Score = 39.7 bits (91), Expect = 0.016
 Identities = 43/179 (24%), Positives = 77/179 (43%), Gaps = 18/179 (10%)

Query: 72  KPFCCSACPFSSKFFSAYKSHFRNVHSED--FENRILLNCPYCTFNADKKTLETHIKIFH 129
           KP+ C  C +++   S+   H R +HS++  F+ +I   CPY + N+ + T+        
Sbjct: 147 KPYKCKTCDYAAADSSSLNKHLR-IHSDERPFKCQI---CPYASRNSSQLTVHLRSHTGD 202

Query: 130 APNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHF 189
           AP        L + K K  +D  +  +  S E+  + C+ C  R  +   ++ HI  +H 
Sbjct: 203 APF----QCWLCSAKFKISSDLKRHMRVHSGEKP-FKCEFCNVRCTMKGNLKSHIRIKHS 257

Query: 190 -QHVAAPYIAKAGEKSLNGAVPLGSNAREESSIHCKRCLFMPKSYEALVQHVIEDHERI 247
             +   P+    G+        L  ++R   S H ++C     SY    +  +  HERI
Sbjct: 258 GNNFKCPHCDFLGDSK----ATLRKHSRVHQSEHPEKC--SECSYSCSSKAALRIHERI 310



 Score = 37.7 bits (86), Expect = 0.060
 Identities = 39/161 (24%), Positives = 57/161 (35%), Gaps = 21/161 (13%)

Query: 72  KPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKK-TLETHIKIF-- 128
           KPF C  C          KSH R  HS +        CP+C F  D K TL  H ++   
Sbjct: 231 KPFKCEFCNVRCTMKGNLKSHIRIKHSGN-----NFKCPHCDFLGDSKATLRKHSRVHQS 285

Query: 129 -HAPNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYRE 187
            H    S  S S S+         L+  +        + C  C++       + KH+ + 
Sbjct: 286 EHPEKCSECSYSCSS------KAALRIHERIHCTDRPFKCNYCSFDTKQPSNLSKHMKKF 339

Query: 188 HFQHVAAPYIAK--AGEKSLNGAVPLGSNAREESSIHCKRC 226
           H   V    + +   G +S      L +    + S HC  C
Sbjct: 340 HGDMVKTEALERKDTGRQSSRQVAKLDA----KKSFHCDIC 376


>gi|40806223 zinc finger protein 64 isoform a [Homo sapiens]
          Length = 681

 Score = 39.7 bits (91), Expect = 0.016
 Identities = 43/179 (24%), Positives = 77/179 (43%), Gaps = 18/179 (10%)

Query: 72  KPFCCSACPFSSKFFSAYKSHFRNVHSED--FENRILLNCPYCTFNADKKTLETHIKIFH 129
           KP+ C  C +++   S+   H R +HS++  F+ +I   CPY + N+ + T+        
Sbjct: 201 KPYKCKTCDYAAADSSSLNKHLR-IHSDERPFKCQI---CPYASRNSSQLTVHLRSHTGD 256

Query: 130 APNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHF 189
           AP        L + K K  +D  +  +  S E+  + C+ C  R  +   ++ HI  +H 
Sbjct: 257 APF----QCWLCSAKFKISSDLKRHMRVHSGEKP-FKCEFCNVRCTMKGNLKSHIRIKHS 311

Query: 190 -QHVAAPYIAKAGEKSLNGAVPLGSNAREESSIHCKRCLFMPKSYEALVQHVIEDHERI 247
             +   P+    G+        L  ++R   S H ++C     SY    +  +  HERI
Sbjct: 312 GNNFKCPHCDFLGDSK----ATLRKHSRVHQSEHPEKC--SECSYSCSSKAALRIHERI 364



 Score = 37.7 bits (86), Expect = 0.060
 Identities = 39/161 (24%), Positives = 57/161 (35%), Gaps = 21/161 (13%)

Query: 72  KPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKK-TLETHIKIF-- 128
           KPF C  C          KSH R  HS +        CP+C F  D K TL  H ++   
Sbjct: 285 KPFKCEFCNVRCTMKGNLKSHIRIKHSGN-----NFKCPHCDFLGDSKATLRKHSRVHQS 339

Query: 129 -HAPNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYRE 187
            H    S  S S S+         L+  +        + C  C++       + KH+ + 
Sbjct: 340 EHPEKCSECSYSCSS------KAALRIHERIHCTDRPFKCNYCSFDTKQPSNLSKHMKKF 393

Query: 188 HFQHVAAPYIAK--AGEKSLNGAVPLGSNAREESSIHCKRC 226
           H   V    + +   G +S      L +    + S HC  C
Sbjct: 394 HGDMVKTEALERKDTGRQSSRQVAKLDA----KKSFHCDIC 430


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.128    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,931,173
Number of Sequences: 37866
Number of extensions: 2378197
Number of successful extensions: 11306
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 501
Number of HSP's that attempted gapping in prelim test: 9772
Number of HSP's gapped (non-prelim): 1944
length of query: 1102
length of database: 18,247,518
effective HSP length: 113
effective length of query: 989
effective length of database: 13,968,660
effective search space: 13815004740
effective search space used: 13815004740
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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