Guide to the Human Genome
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Name: VAV3 Sequence: fasta or formatted (847aa) NCBI GI: 120432044
Description:

vav 3 guanine nucleotide exchange factor isoform 1

Referenced in:

Rho and Rac

Other entries for this name:
alt prot [287aa] vav 3 guanine nucleotide exchange factor isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.1         43           2
 C cysteine            2.8         24           2
 D aspartate           5.7         48           1
 E glutamate           8.4         71           2
 F phenylalanine       4.4         37           2
 G glycine             5.5         47           2
 H histidine           2.6         22           2
 I isoleucine          5.0         42           2
 K lysine              7.9         67           3
 L leucine            10.9         92           3
 M methionine          2.0         17           1
 N asparagine          5.0         42           2
 P proline             4.3         36           3
 Q glutamine           4.5         38           2
 R arginine            5.7         48           2
 S serine              4.6         39           2
 T threonine           5.4         46           2
 V valine              5.3         45           2
 W tryptophan          1.2         10           2
 Y tyrosine            3.9         33           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   vav 3 guanine nucleotide exchange factor isoform 1 ... 
VAV1                  0.575   vav 1 guanine nucleotide exchange factor 
VAV2                  0.530   vav 2 guanine nucleotide exchange factor isoform 2 [...
VAV2                  0.520   vav 2 guanine nucleotide exchange factor isoform 1 ...
VAV3                  0.324   vav 3 guanine nucleotide exchange factor isoform 2 ...
SPATA13               0.043   spermatogenesis associated 13 
PREX1                 0.043   phosphatidylinositol-3,4,5-trisphosphate-dependent R...
PLEKHG1               0.042   pleckstrin homology domain containing, family G (wit...
GRAP                  0.041   GRB2-related adaptor protein 
PREX2                 0.041   DEP domain containing 2 isoform b 
PREX2                 0.041   DEP domain containing 2 isoform a 
ARHGEF4               0.040   Rho guanine nucleotide exchange factor 4 isoform a [...
ARHGEF4               0.040   Rho guanine nucleotide exchange factor 4 isoform b [...
ECT2                  0.037   epithelial cell transforming sequence 2 oncogene pro...
ARHGEF17              0.037   Rho guanine nucleotide exchange factor (GEF) 17 [Hom...
ARHGEF9               0.037   Cdc42 guanine exchange factor 9 
PLEKHG2               0.036   common-site lymphoma/leukemia guanine nucleotide ex...
PLCG2                 0.033   phospholipase C, gamma 2 
PLEKHG3               0.033   pleckstrin homology domain containing, family G, mem...
PLCG1                 0.032   phospholipase C, gamma 1 isoform a 
PLCG1                 0.032   phospholipase C, gamma 1 isoform b 
GRB2                  0.031   growth factor receptor-bound protein 2 isoform 1 [Hom...
TIAM2                 0.031   T-cell lymphoma invasion and metastasis 2 isoform b ...
TIAM2                 0.031   T-cell lymphoma invasion and metastasis 2 isoform a ...
TIAM1                 0.031   T-cell lymphoma invasion and metastasis 1 
FGD3                  0.031   FYVE, RhoGEF and PH domain containing 3 
FGD3                  0.031   FYVE, RhoGEF and PH domain containing 3 
MCF2                  0.029   MCF.2 cell line derived transforming sequence isofo...
MCF2                  0.029   MCF.2 cell line derived transforming sequence isofo...
ARHGEF3               0.029   Rho guanine nucleotide exchange factor 3 isoform 2 ...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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