BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|24308111 FGFR1 oncogene partner 2 [Homo sapiens] (253 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|24308111 FGFR1 oncogene partner 2 [Homo sapiens] 487 e-138 gi|156151377 suppressor of IKK epsilon isoform 2 [Homo sapiens] 185 4e-47 gi|156151379 suppressor of IKK epsilon isoform 1 [Homo sapiens] 182 2e-46 gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 50 2e-06 gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 50 2e-06 gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo... 50 2e-06 gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens] 49 4e-06 gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens] 48 7e-06 gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 48 9e-06 gi|21735548 centrosomal protein 2 [Homo sapiens] 47 1e-05 gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 47 2e-05 gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 47 2e-05 gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 47 2e-05 gi|62243374 MAD1-like 1 protein [Homo sapiens] 45 8e-05 gi|62243369 MAD1-like 1 protein [Homo sapiens] 45 8e-05 gi|62243332 MAD1-like 1 protein [Homo sapiens] 45 8e-05 gi|87298937 centrosomal protein 110kDa [Homo sapiens] 45 8e-05 gi|169208036 PREDICTED: similar to Golgin subfamily A member 8-l... 44 1e-04 gi|239745147 PREDICTED: similar to Golgin subfamily A member 8-l... 44 1e-04 gi|169208014 PREDICTED: Golgin subfamily A member 8-like protein... 44 1e-04 gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein... 44 1e-04 gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] 44 1e-04 gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 44 1e-04 gi|239745132 PREDICTED: similar to Golgin subfamily A member 8-l... 44 2e-04 gi|239745130 PREDICTED: similar to Golgin subfamily A member 8-l... 44 2e-04 gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 43 2e-04 gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 43 2e-04 gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] 43 2e-04 gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 43 2e-04 gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 43 3e-04 >gi|24308111 FGFR1 oncogene partner 2 [Homo sapiens] Length = 253 Score = 487 bits (1253), Expect = e-138 Identities = 253/253 (100%), Positives = 253/253 (100%) Query: 1 MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHR 60 MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHR Sbjct: 1 MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHR 60 Query: 61 PRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDP 120 PRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDP Sbjct: 61 PRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDP 120 Query: 121 GIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQIT 180 GIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQIT Sbjct: 121 GIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQIT 180 Query: 181 EMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDDASESTSLS 240 EMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDDASESTSLS Sbjct: 181 EMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDDASESTSLS 240 Query: 241 ALVTNSDLSLRKS 253 ALVTNSDLSLRKS Sbjct: 241 ALVTNSDLSLRKS 253 >gi|156151377 suppressor of IKK epsilon isoform 2 [Homo sapiens] Length = 207 Score = 185 bits (469), Expect = 4e-47 Identities = 107/246 (43%), Positives = 151/246 (61%), Gaps = 51/246 (20%) Query: 1 MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMK--------QYQEEIQE 52 MSCTIEK L DAK L+ERLR+HD AAESL++Q+ AL++RV AM+ QYQE+ + Sbjct: 1 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASD 60 Query: 53 LNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLL 112 + ++++++P L QEN QIR+LQQEN+EL SLEEHQ ALELIMSKYR+QM +L+ Sbjct: 61 MKDMSKYKPHILL----SQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM 116 Query: 113 MASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNEL 172 +A K D ++K + HS E+ Sbjct: 117 VAKKAVDAEPVLKAHQSHSA--------------------------------------EI 138 Query: 173 QAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDD 232 ++ +D+I EM VMRKA+++D+ Q CK QE++ QLE ENK LRE+L I+ ES L RK++ Sbjct: 139 ESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSES-LQARKEN 197 Query: 233 ASESTS 238 + ++ S Sbjct: 198 SMDTAS 203 >gi|156151379 suppressor of IKK epsilon isoform 1 [Homo sapiens] Length = 211 Score = 182 bits (462), Expect = 2e-46 Identities = 106/250 (42%), Positives = 151/250 (60%), Gaps = 55/250 (22%) Query: 1 MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQ------------YQE 48 MSCTIEK L DAK L+ERLR+HD AAESL++Q+ AL++RV AM++ YQE Sbjct: 1 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQE 60 Query: 49 EIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQM 108 + ++ ++++++P L QEN QIR+LQQEN+EL SLEEHQ ALELIMSKYR+QM Sbjct: 61 DASDMKDMSKYKPHILL----SQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQM 116 Query: 109 FRLLMASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEAN 168 +L++A K D ++K + HS Sbjct: 117 LQLMVAKKAVDAEPVLKAHQSHSA------------------------------------ 140 Query: 169 QNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNL 228 E+++ +D+I EM VMRKA+++D+ Q CK QE++ QLE ENK LRE+L I+ ES L Sbjct: 141 --EIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSES-LQA 197 Query: 229 RKDDASESTS 238 RK+++ ++ S Sbjct: 198 RKENSMDTAS 207 >gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sapiens] Length = 1843 Score = 50.1 bits (118), Expect = 2e-06 Identities = 51/247 (20%), Positives = 108/247 (43%), Gaps = 26/247 (10%) Query: 5 IEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRST 64 ++K + + K E++ + L + L K +++ K +++ L + Sbjct: 644 LQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEEN 703 Query: 65 L-----VMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYR-------------- 105 L V ++ + ++ +LQ ENKEL + E+ + LEL+ + ++ Sbjct: 704 LELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDI 763 Query: 106 --EQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERR 163 +++ + L S K + +L++ + + +N E L S LE Q E + Sbjct: 764 ENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEE---LKISSKRLE--QLEKENK 818 Query: 164 HLEANQNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRE 223 LE ++L+ Q+ + +R+ EI + + +I LE+ENK L + + I +E Sbjct: 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKE 878 Query: 224 SFLNLRK 230 S + L++ Sbjct: 879 SCVRLKE 885 Score = 43.5 bits (101), Expect = 2e-04 Identities = 50/234 (21%), Positives = 112/234 (47%), Gaps = 20/234 (8%) Query: 4 TIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRS 63 T++K L + K +RL + +SL ++T+ L K KQ ++E + L + A + + Sbjct: 795 TLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKD---KKQLEKENKRLRQQAEIKDTT 851 Query: 64 TLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGII 123 +++ N +I L++ENK L + ++ + + K E+ + L+ D + Sbjct: 852 -----LEENNVKIGNLEKENKTLSKEIGIYKESC--VRLKELEKENKELVKRATIDIKTL 904 Query: 124 MKLKEQHSKIDMVHRN-KSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQITE- 181 + L+E D+V K++ D + E + GL + L ++ ++ E Sbjct: 905 VTLRE-----DLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLES 959 Query: 182 -MAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESF--LNLRKDD 232 + + ++K++EI E++ + R+ + N+ LR+ L+ ++++ L R+D+ Sbjct: 960 KLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE 1013 Score = 41.2 bits (95), Expect = 9e-04 Identities = 54/253 (21%), Positives = 105/253 (41%), Gaps = 35/253 (13%) Query: 9 LADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMG 68 LADAKA + RLR E EQ + +E M+ + +Q+ N M Sbjct: 253 LADAKAKIRRLRQE---LEEKTEQLLDCKQELEQMEIELKRLQQEN------------MN 297 Query: 69 IQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQM-----FRLLMASKKDDPGII 123 + + R R + E LR LE +S+Y+E++ ++ + K+D ++ Sbjct: 298 LLSDARSARMYRDELDALREK-AVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVL 356 Query: 124 MKLKEQ--------HSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNE-LQA 174 ++ K ++ D +H + E L A H +E + ++R+ +E E + Sbjct: 357 LETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEM-ERDMDRKKIEELMEENMTL 415 Query: 175 HVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDDAS 234 + Q M + E+++ E + + Q++ G E+ ++T L L ++ S Sbjct: 416 EMAQKQSMDESLHLGWELEQISRTSE---LSEAPQKSLG-HEVNELTSSRLLKLEMENQS 471 Query: 235 ESTSLSALVTNSD 247 + ++ L T D Sbjct: 472 LTKTVEELRTTVD 484 Score = 40.8 bits (94), Expect = 0.001 Identities = 44/217 (20%), Positives = 91/217 (41%), Gaps = 22/217 (10%) Query: 47 QEEIQELNEVARHRPRSTLVMGIQQENRQIR----ELQQENKELRTSLEE--HQSALELI 100 Q E Q N A+ + +Q++N ++ +LQ EN L + +Q+A LI Sbjct: 1071 QLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLI 1130 Query: 101 MSKYREQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRH-ILEAPQHG 159 E ++ ++D + L + H K++++H ++ + S+H L++ Sbjct: 1131 QQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKN 1190 Query: 160 LERRH--LEANQNELQAHVDQITEMAAVMR-------------KAIEIDEQQGCKEQERI 204 LE H LE N+L Q+ ++ +++ + + + ++ C E +R+ Sbjct: 1191 LEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRL 1250 Query: 205 FQLEQENKGLREILQITRESFLNLRKDDASESTSLSA 241 + E+LQ ++ +L + E T L A Sbjct: 1251 NHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEA 1287 Score = 38.1 bits (87), Expect = 0.007 Identities = 46/246 (18%), Positives = 101/246 (41%), Gaps = 33/246 (13%) Query: 16 VERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQ 75 ++ LR+ + L + + +R+ ++ Y+ ++EL E + + ++ Q E + Sbjct: 312 LDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTR 371 Query: 76 IR-----ELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQH 130 R EL++EN +L+ L + + ++ K E M + + +++ ++ Sbjct: 372 ARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELM----------EENMTLEMAQKQ 421 Query: 131 SKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQN---ELQAHVDQITEMAAVMR 187 S + +H E + + + EAPQ L E + +L+ +T+ +R Sbjct: 422 SMDESLHLG-WELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR 480 Query: 188 KAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFL----------NLRKDDASEST 237 ++ E K I ++E+EN+ L + ++I + NL KD E Sbjct: 481 TTVDSVEGNASK----ILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKA 536 Query: 238 SLSALV 243 L + Sbjct: 537 QLEKTI 542 Score = 35.4 bits (80), Expect = 0.048 Identities = 51/237 (21%), Positives = 108/237 (45%), Gaps = 34/237 (14%) Query: 4 TIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAM-------KQYQEEIQELN-E 55 ++ K + + + V+ + + + ++ L+K+VE + KQ + Q L+ + Sbjct: 471 SLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKD 530 Query: 56 VARHRPRSTLVMGIQQEN--RQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLM 113 + + + + + +EN RQI+ L+QEN+ L ++ + ++ + + Sbjct: 531 LMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDI----- 585 Query: 114 ASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLER-RHLEANQNEL 172 +K++ + +KE SK+ + K R I + +H E+ E +NEL Sbjct: 586 --EKENKILHESIKETSSKLSKIEFEK---------RQIKKELEHYKEKGERAEELENEL 634 Query: 173 QAHVDQITEMAAVMRKAIEID-EQQGCKEQERIFQLEQENKGLREILQITRESFLNL 228 H+++ E+ ++I E+ EQE +LE+EN+ L++ T +SF NL Sbjct: 635 H-HLEKENELLQKKITNLKITCEKIEALEQEN-SELERENRKLKK----TLDSFKNL 685 >gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo sapiens] Length = 1870 Score = 50.1 bits (118), Expect = 2e-06 Identities = 51/247 (20%), Positives = 108/247 (43%), Gaps = 26/247 (10%) Query: 5 IEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRST 64 ++K + + K E++ + L + L K +++ K +++ L + Sbjct: 644 LQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEEN 703 Query: 65 L-----VMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYR-------------- 105 L V ++ + ++ +LQ ENKEL + E+ + LEL+ + ++ Sbjct: 704 LELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDI 763 Query: 106 --EQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERR 163 +++ + L S K + +L++ + + +N E L S LE Q E + Sbjct: 764 ENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEE---LKISSKRLE--QLEKENK 818 Query: 164 HLEANQNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRE 223 LE ++L+ Q+ + +R+ EI + + +I LE+ENK L + + I +E Sbjct: 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKE 878 Query: 224 SFLNLRK 230 S + L++ Sbjct: 879 SCVRLKE 885 Score = 43.9 bits (102), Expect = 1e-04 Identities = 49/233 (21%), Positives = 112/233 (48%), Gaps = 19/233 (8%) Query: 4 TIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRS 63 T++K L + K +RL + +SL ++T+ L K KQ ++E + L + A + + Sbjct: 795 TLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKD---KKQLEKENKRLRQQAEIKDTT 851 Query: 64 TLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGII 123 +++ N +I L++ENK L + ++ + + K E+ + L+ D + Sbjct: 852 -----LEENNVKIGNLEKENKTLSKEIGIYKESC--VRLKELEKENKELVKRATIDIKTL 904 Query: 124 MKLKEQHSKIDMVHRN-KSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQI-TE 181 + L+E D+V K++ D + E + GL + L ++ + ++ Sbjct: 905 VTLRE-----DLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESK 959 Query: 182 MAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESF--LNLRKDD 232 + + ++K++EI E++ + R+ + N+ LR+ L+ ++++ L R+D+ Sbjct: 960 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE 1012 Score = 41.2 bits (95), Expect = 9e-04 Identities = 54/253 (21%), Positives = 105/253 (41%), Gaps = 35/253 (13%) Query: 9 LADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMG 68 LADAKA + RLR E EQ + +E M+ + +Q+ N M Sbjct: 253 LADAKAKIRRLRQE---LEEKTEQLLDCKQELEQMEIELKRLQQEN------------MN 297 Query: 69 IQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQM-----FRLLMASKKDDPGII 123 + + R R + E LR LE +S+Y+E++ ++ + K+D ++ Sbjct: 298 LLSDARSARMYRDELDALREK-AVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVL 356 Query: 124 MKLKEQ--------HSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNE-LQA 174 ++ K ++ D +H + E L A H +E + ++R+ +E E + Sbjct: 357 LETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEM-ERDMDRKKIEELMEENMTL 415 Query: 175 HVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDDAS 234 + Q M + E+++ E + + Q++ G E+ ++T L L ++ S Sbjct: 416 EMAQKQSMDESLHLGWELEQISRTSE---LSEAPQKSLG-HEVNELTSSRLLKLEMENQS 471 Query: 235 ESTSLSALVTNSD 247 + ++ L T D Sbjct: 472 LTKTVEELRTTVD 484 Score = 40.8 bits (94), Expect = 0.001 Identities = 44/217 (20%), Positives = 91/217 (41%), Gaps = 22/217 (10%) Query: 47 QEEIQELNEVARHRPRSTLVMGIQQENRQIR----ELQQENKELRTSLEE--HQSALELI 100 Q E Q N A+ + +Q++N ++ +LQ EN L + +Q+A LI Sbjct: 1070 QLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLI 1129 Query: 101 MSKYREQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRH-ILEAPQHG 159 E ++ ++D + L + H K++++H ++ + S+H L++ Sbjct: 1130 QQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKN 1189 Query: 160 LERRH--LEANQNELQAHVDQITEMAAVMR-------------KAIEIDEQQGCKEQERI 204 LE H LE N+L Q+ ++ +++ + + + ++ C E +R+ Sbjct: 1190 LEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRL 1249 Query: 205 FQLEQENKGLREILQITRESFLNLRKDDASESTSLSA 241 + E+LQ ++ +L + E T L A Sbjct: 1250 NHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEA 1286 Score = 38.1 bits (87), Expect = 0.007 Identities = 46/246 (18%), Positives = 101/246 (41%), Gaps = 33/246 (13%) Query: 16 VERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQ 75 ++ LR+ + L + + +R+ ++ Y+ ++EL E + + ++ Q E + Sbjct: 312 LDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTR 371 Query: 76 IR-----ELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQH 130 R EL++EN +L+ L + + ++ K E M + + +++ ++ Sbjct: 372 ARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELM----------EENMTLEMAQKQ 421 Query: 131 SKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQN---ELQAHVDQITEMAAVMR 187 S + +H E + + + EAPQ L E + +L+ +T+ +R Sbjct: 422 SMDESLHLG-WELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR 480 Query: 188 KAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFL----------NLRKDDASEST 237 ++ E K I ++E+EN+ L + ++I + NL KD E Sbjct: 481 TTVDSVEGNASK----ILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKA 536 Query: 238 SLSALV 243 L + Sbjct: 537 QLEKTI 542 Score = 35.4 bits (80), Expect = 0.048 Identities = 51/237 (21%), Positives = 108/237 (45%), Gaps = 34/237 (14%) Query: 4 TIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAM-------KQYQEEIQELN-E 55 ++ K + + + V+ + + + ++ L+K+VE + KQ + Q L+ + Sbjct: 471 SLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKD 530 Query: 56 VARHRPRSTLVMGIQQEN--RQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLM 113 + + + + + +EN RQI+ L+QEN+ L ++ + ++ + + Sbjct: 531 LMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDI----- 585 Query: 114 ASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLER-RHLEANQNEL 172 +K++ + +KE SK+ + K R I + +H E+ E +NEL Sbjct: 586 --EKENKILHESIKETSSKLSKIEFEK---------RQIKKELEHYKEKGERAEELENEL 634 Query: 173 QAHVDQITEMAAVMRKAIEID-EQQGCKEQERIFQLEQENKGLREILQITRESFLNL 228 H+++ E+ ++I E+ EQE +LE+EN+ L++ T +SF NL Sbjct: 635 H-HLEKENELLQKKITNLKITCEKIEALEQEN-SELERENRKLKK----TLDSFKNL 685 >gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo sapiens] Length = 805 Score = 49.7 bits (117), Expect = 2e-06 Identities = 52/232 (22%), Positives = 108/232 (46%), Gaps = 33/232 (14%) Query: 11 DAKALVERLRDHDDAAESL-------IEQTTALNKRVEAMKQYQEEIQELNEVARHRPRS 63 + K L E+L+ D SL EQ +R+E +++Y ++ L++V Sbjct: 472 EKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDV------- 524 Query: 64 TLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGII 123 Q ++ Q++ L+++NK L+ +L + + LE I + +++ +L+ KK + ++ Sbjct: 525 ------QSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQLI-CQKKKEKELV 577 Query: 124 MKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQITEMA 183 ++ K++ R +G L +L+A Q E +L QNE + + ++ Sbjct: 578 TTVQSLQQKVE---RCLEDGIRLP----MLDAKQLQNENDNLR-QQNETASKIID-SQQD 628 Query: 184 AVMRKAIEIDEQQGCKEQERIF---QLEQENKGLREILQITRESFLNLRKDD 232 + R +EI QG +E++ +E+ K R + ++T+ N R+ D Sbjct: 629 EIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTD 680 >gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens] Length = 1133 Score = 48.9 bits (115), Expect = 4e-06 Identities = 57/245 (23%), Positives = 103/245 (42%), Gaps = 39/245 (15%) Query: 19 LRDHD-DAAESLIEQTTALNKRVEAMKQYQEEIQELN---EVARHRPRSTLVMGIQQENR 74 L+D + DAA S T +LN + M+++ + EL+ E + +GI+Q + Sbjct: 718 LKDREVDAATSATSHTRSLNSIIHQMEKFSSSLHELSSRVEASHLTTSQERELGIRQRDE 777 Query: 75 QIRELQQENKELRTSLEEHQSALELIMSKYR---EQMFRLLMASKKDDPGIIMKLKEQHS 131 Q+R LQ+ + + +EE +S + ++ K + RLL + ++ + S Sbjct: 778 QLRALQERLGQQQRDMEEERSRQQEVIGKMEARLNEQSRLLEQER-------WRVTAEQS 830 Query: 132 KIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQITEMAAVMRKAIE 191 K + + R E + + A Q +ER LE ++ L + E +VM K Sbjct: 831 KAESMQRALEE-------QRKVTAQQMAMERAELERAKSAL------LEEQKSVMLK--- 874 Query: 192 IDEQQGCKEQERIFQLEQENKGLREIL---QITRESFLNLRKDDASESTSLSALVTNSDL 248 C E+ R E ++ L + RE+ L+ D E T +S ++L Sbjct: 875 ------CGEERRRLAAEWAEFSAQQKLSKERAEREAERALQVDTQREGTLISLAKEQAEL 928 Query: 249 SLRKS 253 +R S Sbjct: 929 KIRAS 933 >gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens] Length = 731 Score = 48.1 bits (113), Expect = 7e-06 Identities = 62/238 (26%), Positives = 108/238 (45%), Gaps = 24/238 (10%) Query: 27 ESLIEQTTALNKRVEAMKQYQEEIQ-ELNEVARHRPRSTLVMGIQQ-----ENRQIRELQ 80 E L E L + E+ KQ Q E LN+V R + + + E +++ ELQ Sbjct: 352 ERLHEADATLKREQESYKQMQSEFAARLNKVEMERQNLAEAITLAERKYSDEKKRVDELQ 411 Query: 81 QENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRNK 140 Q+ K + +LE S ELI Y+++ R+L + +K +I LKE S + + + Sbjct: 412 QQVKLYKLNLES--SKQELI--DYKQKATRILQSKEK----LINSLKEG-SGFEGLDSST 462 Query: 141 SEGFFLDASRHILEAPQHGLERRHLEANQ--NELQ-AHVDQITEMAAVMRKAIEIDEQ-- 195 + L+ RH E + +++ + +Q +ELQ Q+ E + + ++ +Q Sbjct: 463 ASSMELEELRHEKEMQREEIQKLMGQIHQLRSELQDMEAQQVNEAESAREQLQDLHDQIA 522 Query: 196 -QGCKEQE---RIFQLEQENKGLREILQITRESFLNLRKDDASESTSLSALVTNSDLS 249 Q +QE + +L+QE + E L T+ + + KD E L +TN LS Sbjct: 523 GQKASKQELETELERLKQEFHYIEEDLYRTKNTLQSRIKDRDEEIQKLRNQLTNKTLS 580 Score = 33.5 bits (75), Expect = 0.18 Identities = 41/206 (19%), Positives = 95/206 (46%), Gaps = 10/206 (4%) Query: 29 LIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRT 88 L + +LN+ + ++ Q +E QE AR R + +R R L+ + +L Sbjct: 234 LRNEVQSLNQEMASLLQRSKETQEELNKARARVEKWNA-DHSKSDRMTRGLRAQVDDLTE 292 Query: 89 SLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQHSKI--DMVHRNKSEGFFL 146 ++ S L ++ K R Q L++++ + + L+ + S+I D N + L Sbjct: 293 AVAAKDSQLAVL--KVRLQEADQLLSTRTE---ALEALQSEKSRIMQDQSEGNSLQNQAL 347 Query: 147 DASRHILEAPQHGLERRH--LEANQNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERI 204 + L L+R + Q+E A ++++ + +AI + E++ E++R+ Sbjct: 348 QTFQERLHEADATLKREQESYKQMQSEFAARLNKVEMERQNLAEAITLAERKYSDEKKRV 407 Query: 205 FQLEQENKGLREILQITRESFLNLRK 230 +L+Q+ K + L+ +++ ++ ++ Sbjct: 408 DELQQQVKLYKLNLESSKQELIDYKQ 433 >gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo sapiens] Length = 1938 Score = 47.8 bits (112), Expect = 9e-06 Identities = 48/221 (21%), Positives = 96/221 (43%), Gaps = 19/221 (8%) Query: 5 IEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRST 64 +E A ++++L L +A E +++Q L + K QEEI +L E ++ Sbjct: 1471 LEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRE---NKNLQEEISDLTEQIAETGKN- 1526 Query: 65 LVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIM 124 +Q+ + + ++QE +L+ +LEE + +LE SK L + D +I Sbjct: 1527 ----LQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVI- 1581 Query: 125 KLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLE-----RRHLEANQNELQAHVDQI 179 E+ +I+ + RN +A + +L+A ++ +E + NE++ + Sbjct: 1582 ---EKDEEIEQLKRNSQRA--AEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHS 1636 Query: 180 TEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQI 220 A +K + + Q Q + + N+ L+E L I Sbjct: 1637 NRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAI 1677 Score = 33.9 bits (76), Expect = 0.14 Identities = 49/225 (21%), Positives = 95/225 (42%), Gaps = 24/225 (10%) Query: 23 DDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIR---EL 79 ++ ++L E+ TAL + + + + ++ +QE A + L + + N I+ +L Sbjct: 976 ENKVKNLSEEMTALEENISKLTKEKKSLQE----AHQQTLDDLQVEEDKVNGLIKINAKL 1031 Query: 80 QQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRN 139 +Q+ +L SLE+ + + E+ R L K IM L+ +I+ + Sbjct: 1032 EQQTDDLEGSLEQEKK-----LRADLERAKRKLEGDLKMSQESIMDLENDKQQIE--EKL 1084 Query: 140 KSEGFFLDASRHILEAPQ-HGLERRHLEANQNELQAHVDQI---TEMAAVMRKAIEIDEQ 195 K + F L + ++ Q H L+ + ELQA ++++ E +R IE Sbjct: 1085 KKKEFELSQLQAKIDDEQVHSLQ---FQKKIKELQARIEELEEEIEAEHTLRAKIEKQRS 1141 Query: 196 QGCKEQERIFQLEQENKGLREI---LQITRESFLNLRKDDASEST 237 +E E I + +E G + RE+ + D E+T Sbjct: 1142 DLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEAT 1186 Score = 31.2 bits (69), Expect = 0.91 Identities = 25/130 (19%), Positives = 59/130 (45%), Gaps = 16/130 (12%) Query: 6 EKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTL 65 +KA+ DA + E L+ D + L L + V+ ++ +E ++L Sbjct: 1760 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQL------------ 1807 Query: 66 VMGIQQENRQIRELQQENKELRTSLE-EHQSALELIMSKYR-EQMFRLLMASKKDDPGII 123 ++ +QI++L+ +EL L+ E + E + ++ E+ + + ++D I Sbjct: 1808 --ALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNI 1865 Query: 124 MKLKEQHSKI 133 ++L++ K+ Sbjct: 1866 LRLQDLVDKL 1875 >gi|21735548 centrosomal protein 2 [Homo sapiens] Length = 2442 Score = 47.4 bits (111), Expect = 1e-05 Identities = 62/255 (24%), Positives = 113/255 (44%), Gaps = 43/255 (16%) Query: 5 IEKALADAKALVERLRDHDDAAESLIEQTTA--------LNKRVEAMKQYQEEIQELNE- 55 + + LA+ + VE LR E E A L KR + + QE+IQEL + Sbjct: 1426 LTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKC 1485 Query: 56 --VARHRPRSTLVMGIQQ-------ENRQIRELQQENKELRTSLEEHQSALELIMSKYRE 106 V H P M +Q+ + QIREL+++ + R LE +L+ + ++ Sbjct: 1486 RSVLEHLP-----MAVQEREQKLTVQREQIRELEKDRETQRNVLEH-----QLLELEKKD 1535 Query: 107 QMFRLLMASKKDDPG-------IIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHG 159 QM +D + ++L+E H K++ + E L+ R Sbjct: 1536 QMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKE---LEGQRETQRVALTH 1592 Query: 160 LERRHLEANQNELQAHVDQITEM---AAVMRKAIEIDEQQGCKEQERIFQLEQENKGLRE 216 L LE ELQA QI ++ + V+ + ++ +Q+ ++E+I +L+++ + L + Sbjct: 1593 L-TLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQ 1651 Query: 217 ILQITRESFLNLRKD 231 L+ R+ L L+K+ Sbjct: 1652 DLE-RRDQELMLQKE 1665 Score = 45.1 bits (105), Expect = 6e-05 Identities = 51/209 (24%), Positives = 91/209 (43%), Gaps = 17/209 (8%) Query: 5 IEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRST 64 +E+A K L+DH + A L E+ +RV+A+ +E + +L +R + ++ Sbjct: 1847 LEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQAL---EEVLGDLRAESREQEKAL 1903 Query: 65 LVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIM 124 L + QQ Q +E + E + L+ S + Q+ L K R+Q L A + Sbjct: 1904 LALQ-QQCAEQAQEHEVETRALQDSWLQAQAVL-----KERDQELEALRAESQSSRHQEE 1957 Query: 125 KLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQITEMAA 184 + + + K+ +H+LE + R LEA+ LQA +D + Sbjct: 1958 AARARAEALQEA-LGKAHAALQGKEQHLLEQAELS---RSLEASTATLQASLDACQAHSR 2013 Query: 185 VMRKAIEIDE----QQGCKEQERIFQLEQ 209 + +A+ I E Q + QE + QL+Q Sbjct: 2014 QLEEALRIQEGEIQDQDLRYQEDVQQLQQ 2042 Score = 44.3 bits (103), Expect = 1e-04 Identities = 51/244 (20%), Positives = 109/244 (44%), Gaps = 19/244 (7%) Query: 7 KALADAKALVERLRDHDDAAESLIEQTTA-LNKRVEAMKQYQEEIQELNEVARHRPRSTL 65 + L+ AK L+E S+IE T L +++ + Q +E IQ + + Sbjct: 760 QGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTER 819 Query: 66 VMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYRE-----------QMFRLLMA 114 Q+ + R+L Q +E +T+LE+ ++A E +++ RE ++ + L + Sbjct: 820 SQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALES 879 Query: 115 SKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQA 174 +++ + M+LKEQ ++++ + + E S + ER L + Q Sbjct: 880 LEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQK 939 Query: 175 HVDQITEMAAVMRKAIEIDEQQGCKEQERI----FQLEQENKGLREILQITRESFLNLRK 230 + ++ +R+ +++ Q KEQE QL++ + L+E + R+ L++ Sbjct: 940 ELADASQQLERLRQDMKV---QKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQE 996 Query: 231 DDAS 234 + +S Sbjct: 997 ESSS 1000 Score = 43.9 bits (102), Expect = 1e-04 Identities = 55/241 (22%), Positives = 109/241 (45%), Gaps = 21/241 (8%) Query: 11 DAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQ 70 + KAL +RL+ ++L QT L V+++ + +E +Q+ E R + + ++ Sbjct: 429 EGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQ-----LEVLE 483 Query: 71 QENRQIR----ELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKL 126 QE ++R ELQ + + EE Q L L + + RE++ +LM + + +L Sbjct: 484 QEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAV-RERERLQEMLMGLEAKQSESLSEL 542 Query: 127 KEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLER--RHLEANQNELQAHVDQITEMA- 183 ++ H EG L + + A E+ L +++N L+ V + A Sbjct: 543 ITLREALESSH---LEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAV 599 Query: 184 --AVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDDASESTSLSA 241 + + +A+ +D + G +Q + QLE+EN+ + ++ ++ L+ D A A Sbjct: 600 KLSALNEALALD-KVGLNQQ--LLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREA 656 Query: 242 L 242 L Sbjct: 657 L 657 Score = 43.5 bits (101), Expect = 2e-04 Identities = 54/238 (22%), Positives = 104/238 (43%), Gaps = 31/238 (13%) Query: 1 MSCTIEKALADAKALVERLR-------DHDDAAESLIEQTT-ALNKRVEAMKQYQEEIQE 52 + +++ A ++ L E LR D D + ++Q AL +R E ++ QE Q Sbjct: 2001 LQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQL 2060 Query: 53 LNEVARHRPRSTLV-----MGIQQENRQIRELQQENKELRTSL-EEHQSALELIMSKYRE 106 L + R + ++ +G ++E +IR L Q +EL+ +L ++ Q LEL ++ R Sbjct: 2061 LEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRN 2120 Query: 107 QMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLE 166 + L S K P ++EQ K+D + + LE Q L R E Sbjct: 2121 NL-EALPHSHKTSP-----MEEQSLKLDSLE---------PRLQRELERLQAAL--RQTE 2163 Query: 167 ANQNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRES 224 A + E + + A + ++ ++ Q + + + E + L++ L++TR + Sbjct: 2164 AREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRA 2221 Score = 37.4 bits (85), Expect = 0.013 Identities = 49/217 (22%), Positives = 98/217 (45%), Gaps = 31/217 (14%) Query: 6 EKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVAR-HRPRST 64 +K LADA +ERLR + ++TT + Q QE +EL E AR HR Sbjct: 938 QKELADASQQLERLRQDMKVQKLKEQETTGI-----LQTQLQEAQRELKEAARQHRDD-- 990 Query: 65 LVMGIQQENRQI----RELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDP 120 + +Q+E+ + +LQ++ ++L++ L + L+ + +E+ + ++ Sbjct: 991 -LAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEK-----LRETQEYN 1044 Query: 121 GIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQIT 180 I +L+ + + + + K + R ++ + ++ L A + ++Q + Sbjct: 1045 RIQKELEREKASLTLSLMEKEQ-------RLLVLQEADSIRQQELSALRQDMQEAQGEQK 1097 Query: 181 EMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREI 217 E++A M +Q KE+E F L QE + L E+ Sbjct: 1098 ELSAQMELL-----RQEVKEKEADF-LAQEAQLLEEL 1128 Score = 33.9 bits (76), Expect = 0.14 Identities = 45/217 (20%), Positives = 91/217 (41%), Gaps = 33/217 (15%) Query: 4 TIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRS 63 T++ +AD +A +L ++A L LN+++ +++ + + E A + R+ Sbjct: 586 TLKTEVADLRAAAVKLSALNEA---LALDKVGLNQQLLQLEEENQSVCSRMEAAE-QARN 641 Query: 64 TLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGII 123 L + + + ++ L ++N L L++ + A + + R+ I Sbjct: 642 ALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRD----------------I 685 Query: 124 MKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEA-NQNELQAHVDQITEM 182 + KE+ K L SRH EA LE+ H EA Q E+ A Q E Sbjct: 686 QEEKEEIQKK------------LSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEA 733 Query: 183 AAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQ 219 + A+E+ Q ++++ + + Q +E+L+ Sbjct: 734 LVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLE 770 >gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] Length = 1684 Score = 47.0 bits (110), Expect = 2e-05 Identities = 56/240 (23%), Positives = 97/240 (40%), Gaps = 46/240 (19%) Query: 6 EKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTL 65 ++ +D L ++LR ++L+E L E + QE + EL Sbjct: 510 QQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQELVPELENT--------- 560 Query: 66 VMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMK 125 I+ LQ++N SL + + L+ + K + +KDD I K Sbjct: 561 ----------IKNLQEKNGVYLLSLSQRDTMLKELEGKINS------LTEEKDD--FINK 602 Query: 126 LKEQHSKIDMVHR--NKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHV------- 176 LK H ++D H+ + E L+ + + + Q+ E LE NEL + Sbjct: 603 LKNSHEEMDNFHKKCEREERLILELGKKVEQTIQYNSE---LEQKVNELTGGLEETLKEK 659 Query: 177 ---DQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITR--ESFLNLRKD 231 DQ E V K + D++ E + ++ E+ NK E Q++R E FL+ ++D Sbjct: 660 DQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLY--EENNKLSSEKKQLSRDLEVFLSQKED 717 Score = 39.7 bits (91), Expect = 0.003 Identities = 48/260 (18%), Positives = 116/260 (44%), Gaps = 20/260 (7%) Query: 1 MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHR 60 + C E+++ + L LRD++ L ++ + EA++ E++ NE R Sbjct: 815 IKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLE 874 Query: 61 PRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSK-YREQMFRLLM------ 113 ++ L+ +++ ++ + + N++ + ++EH++ L+ K R++ L++ Sbjct: 875 NQNLLIQ-VEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLA 933 Query: 114 --ASKKDDP-GIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQN 170 S K+DP + +L+E+ ++ + K E + + R+ + + Sbjct: 934 KSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKE 993 Query: 171 ELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRK 230 EL++ + +++A MR I QG + + + LE E + + ++ R + R Sbjct: 994 ELESLRSEKDQLSASMRDLI-----QGAESYKNLL-LEYEKQSEQLDVEKERANNFEHRI 1047 Query: 231 DDAS---ESTSLSALVTNSD 247 +D + +++L NSD Sbjct: 1048 EDLTRQLRNSTLQCETINSD 1067 Score = 38.9 bits (89), Expect = 0.004 Identities = 24/74 (32%), Positives = 41/74 (55%), Gaps = 4/74 (5%) Query: 37 NKRVEAMK-QYQEEIQELNEV---ARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEE 92 N+ V+++K Q+Q+EI ELNE + + TL+ IQ Q LQQE +E + E Sbjct: 423 NREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYES 482 Query: 93 HQSALELIMSKYRE 106 + +E++ ++ E Sbjct: 483 LREIMEILQTELGE 496 Score = 35.0 bits (79), Expect = 0.063 Identities = 48/228 (21%), Positives = 98/228 (42%), Gaps = 38/228 (16%) Query: 22 HDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQ 81 H + ++ TAL + A K Q + E + R + L QQ+N+ + + + Sbjct: 1288 HQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVLK---QQKNKSMSQAET 1344 Query: 82 ENK------------ELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQ 129 E +L+ L++ Q+ L++ +S+ + + S+ D L E+ Sbjct: 1345 EGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQT------LQSEHDT------LLER 1392 Query: 130 HSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEA-----NQNEL--QAHVDQITEM 182 H+K M+ S+ L +++ ++ H + +QNE+ + DQ+ + Sbjct: 1393 HNK--MLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHL 1450 Query: 183 AAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRK 230 RK +E +QQ K + ++FQL+ E + +++S NLR+ Sbjct: 1451 QEEHRKTVETLQQQLSKMEAQLFQLKNEPTTRSPV--SSQQSLKNLRE 1496 >gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] Length = 2115 Score = 46.6 bits (109), Expect = 2e-05 Identities = 51/214 (23%), Positives = 93/214 (43%), Gaps = 35/214 (16%) Query: 15 LVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENR 74 L + L+ + A++ L Q L+ ++ +Q +E+ E E R L ++ Sbjct: 535 LAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREA 594 Query: 75 QIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQHSKID 134 +RE K+L +E + LE++ +L +A++ D + + Sbjct: 595 SLRERDAALKQLEALEKEKAAKLEILQQ-------QLQVANEARD--------SAQTSVT 639 Query: 135 MVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQITEMAAVMRKAIEIDE 194 R K+E SR + E Q +E E Q+E QA Q+ E+ +R E Sbjct: 640 QAQREKAE-----LSRKV-EELQACVETARQE--QHEAQA---QVAELELQLR-----SE 683 Query: 195 QQGCKEQERIF----QLEQENKGLREILQITRES 224 QQ E+ER+ QL+++ + L+E L++T+ S Sbjct: 684 QQKATEKERVAQEKDQLQEQLQALKESLKVTKGS 717 Score = 33.5 bits (75), Expect = 0.18 Identities = 30/111 (27%), Positives = 44/111 (39%), Gaps = 21/111 (18%) Query: 6 EKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTL 65 ++ A L +L + AAE Q +A KQ +E+QE Sbjct: 1587 QRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQE------------- 1633 Query: 66 VMGIQQENRQIRELQQENKELRTSLEE--HQSALELIMSKYREQMFRLLMA 114 + R + +LQ+ENKELR E H+ + +K EQ R L A Sbjct: 1634 ------QLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTA 1678 Score = 31.2 bits (69), Expect = 0.91 Identities = 58/275 (21%), Positives = 116/275 (42%), Gaps = 48/275 (17%) Query: 10 ADAKALVERLRDH-DDAAESLIEQTTALNKRVEAMKQYQEEIQELN--------EVARHR 60 A+ + +E L+ ++ A+ L +AL + ++ ++Q+ + +VAR R Sbjct: 1158 AERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGR 1217 Query: 61 P----RSTLVMGIQQE----NRQIRELQQENKEL-RTSLEEHQSALELIMSKYREQMFRL 111 +++L+ +++E NRQ+ E + E+KEL R + E + + +L E+ RL Sbjct: 1218 QEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKL------EERLRL 1271 Query: 112 LMASKKDDPG-----------IIMKLKEQHSKIDMVHRNKSEGFFLDASR-----HILEA 155 L A + + L+E+ K + N + A R L+A Sbjct: 1272 LQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKA 1331 Query: 156 PQHGLERRHLEANQNELQAHVDQ--ITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENK- 212 Q ++ + +L+ Q ++E+ ++ +Q E+ +LEQ + Sbjct: 1332 WQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQA 1391 Query: 213 --GLR-EILQITRE--SFLNLRKDDASESTSLSAL 242 GLR E+L+ RE + LR+ A + + L Sbjct: 1392 AGGLRAELLRAQRELGELIPLRQKVAEQERTAQQL 1426 >gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] Length = 1498 Score = 46.6 bits (109), Expect = 2e-05 Identities = 56/250 (22%), Positives = 112/250 (44%), Gaps = 37/250 (14%) Query: 5 IEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVAR--HRPR 62 IE + D +A ++++ A++++E+ L +R+E + +E +Q + + A + Sbjct: 645 IEADMLDQEAAFMQIQE----AKTMVEED--LQRRLEEFEGERERLQRMADSAASLEQQL 698 Query: 63 STLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGI 122 + + + Q ++Q+ LQQE+ +L L Q AL+ REQ L + Sbjct: 699 EQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQS-----REQSLDALQTHYDELQAR 753 Query: 123 IMKLK-EQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLER--RHLEANQNELQAHVDQI 179 + +L+ E S+ D + ++E L+A+ ++ + L+R R LE E ++++ Sbjct: 754 LGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKL 813 Query: 180 TEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLN-------LRKDD 232 E A+ +E L+QE L++ +Q +E FL R+D Sbjct: 814 REELAIKSGQVE--------------HLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDA 859 Query: 233 ASESTSLSAL 242 S+ +S L Sbjct: 860 TSKDQLISEL 869 Score = 42.4 bits (98), Expect = 4e-04 Identities = 59/294 (20%), Positives = 122/294 (41%), Gaps = 47/294 (15%) Query: 5 IEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEA-MKQYQEEIQELN--------- 54 I++ K +VE R + + LI + A KR+++ +K+ ++E+ +++ Sbjct: 841 IKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAE 900 Query: 55 ------EVARHRPR------------------STLVMGIQQENRQIRELQQENKELRTSL 90 EVA+ R T + +Q + Q+ + + N+ L+ + Sbjct: 901 LSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQI 960 Query: 91 EEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFL---- 146 EE Q +++ +++M RL + K K + + ++ R E Sbjct: 961 EELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAA 1020 Query: 147 DASRHILEAPQHGLE-----RRHLEANQNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQ 201 DA L A + ++A + ELQA T + +++ I + Q+ + + Sbjct: 1021 DAELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKELQEVIALTSQELEESR 1080 Query: 202 ERIFQLE---QENKGLREILQITRESFLNLRKDDASESTSLSALVTNSDLSLRK 252 E++ +LE QE++G R+ ++ ES L + E L+ L S+ +LR+ Sbjct: 1081 EKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGL-GQSNAALRE 1133 Score = 36.6 bits (83), Expect = 0.022 Identities = 49/251 (19%), Positives = 97/251 (38%), Gaps = 50/251 (19%) Query: 13 KALVERLRDHDDAAESLIEQTTA-LNKRVEAMKQYQEEIQELNEVARHRPR--------- 62 +A+++R + D + L++ A L K E + +E++ A H R Sbjct: 1157 QAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLEL 1216 Query: 63 STLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGI 122 S + +Q + +++LQ E +L+ +H + ++ E +L + K+ Sbjct: 1217 SEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQFQAELAEARAQLQLLQKQ----- 1271 Query: 123 IMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQITEM 182 L EQ SK + ++ L+ VDQ Sbjct: 1272 ---LDEQLSKQPVGNQE-----------------------------MENLKWEVDQKERE 1299 Query: 183 AAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDDASESTSLSAL 242 +++ +++ EQQG KE E + QL Q ++ L++ +E +KD +S L Sbjct: 1300 IQSLKQQLDLTEQQGRKELEGLQQLLQ---NVKSELEMAQEDLSMTQKDKFMLQAKVSEL 1356 Query: 243 VTNSDLSLRKS 253 N L+++ Sbjct: 1357 KNNMKTLLQQN 1367 >gi|62243374 MAD1-like 1 protein [Homo sapiens] Length = 718 Score = 44.7 bits (104), Expect = 8e-05 Identities = 49/221 (22%), Positives = 95/221 (42%), Gaps = 24/221 (10%) Query: 9 LADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMG 68 + + +A E DH+ + L ++ + + +K + E+ L + R + Sbjct: 208 IQELQASQEARADHEQQIKDLEQKLSLQEQDAAIVKNMKSELVRLPRLERELKQ------ 261 Query: 69 IQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKE 128 +++E+ +RE+++ N L+ LE Q L +E+M L+ + ++ ++ KL + Sbjct: 262 LREESAHLREMRETNGLLQEELEGLQRKLGR-----QEKMQETLVGLELENERLLAKL-Q 315 Query: 129 QHSKIDMVHRNKSEGFFLDASRHILEAPQHGL-----------ERRHLEANQNELQAHVD 177 ++D S D SR ++E Q L R LE + +LQ + Sbjct: 316 SWERLDQT-MGLSIRTPEDLSRFVVELQQRELALKDKNSAVTSSARGLEKARQQLQEELR 374 Query: 178 QITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREIL 218 Q++ RK E E + Q+R+ L +E G+R IL Sbjct: 375 QVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAIL 415 >gi|62243369 MAD1-like 1 protein [Homo sapiens] Length = 718 Score = 44.7 bits (104), Expect = 8e-05 Identities = 49/221 (22%), Positives = 95/221 (42%), Gaps = 24/221 (10%) Query: 9 LADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMG 68 + + +A E DH+ + L ++ + + +K + E+ L + R + Sbjct: 208 IQELQASQEARADHEQQIKDLEQKLSLQEQDAAIVKNMKSELVRLPRLERELKQ------ 261 Query: 69 IQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKE 128 +++E+ +RE+++ N L+ LE Q L +E+M L+ + ++ ++ KL + Sbjct: 262 LREESAHLREMRETNGLLQEELEGLQRKLGR-----QEKMQETLVGLELENERLLAKL-Q 315 Query: 129 QHSKIDMVHRNKSEGFFLDASRHILEAPQHGL-----------ERRHLEANQNELQAHVD 177 ++D S D SR ++E Q L R LE + +LQ + Sbjct: 316 SWERLDQT-MGLSIRTPEDLSRFVVELQQRELALKDKNSAVTSSARGLEKARQQLQEELR 374 Query: 178 QITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREIL 218 Q++ RK E E + Q+R+ L +E G+R IL Sbjct: 375 QVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAIL 415 >gi|62243332 MAD1-like 1 protein [Homo sapiens] Length = 718 Score = 44.7 bits (104), Expect = 8e-05 Identities = 49/221 (22%), Positives = 95/221 (42%), Gaps = 24/221 (10%) Query: 9 LADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMG 68 + + +A E DH+ + L ++ + + +K + E+ L + R + Sbjct: 208 IQELQASQEARADHEQQIKDLEQKLSLQEQDAAIVKNMKSELVRLPRLERELKQ------ 261 Query: 69 IQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKE 128 +++E+ +RE+++ N L+ LE Q L +E+M L+ + ++ ++ KL + Sbjct: 262 LREESAHLREMRETNGLLQEELEGLQRKLGR-----QEKMQETLVGLELENERLLAKL-Q 315 Query: 129 QHSKIDMVHRNKSEGFFLDASRHILEAPQHGL-----------ERRHLEANQNELQAHVD 177 ++D S D SR ++E Q L R LE + +LQ + Sbjct: 316 SWERLDQT-MGLSIRTPEDLSRFVVELQQRELALKDKNSAVTSSARGLEKARQQLQEELR 374 Query: 178 QITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREIL 218 Q++ RK E E + Q+R+ L +E G+R IL Sbjct: 375 QVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAIL 415 >gi|87298937 centrosomal protein 110kDa [Homo sapiens] Length = 2325 Score = 44.7 bits (104), Expect = 8e-05 Identities = 47/243 (19%), Positives = 109/243 (44%), Gaps = 23/243 (9%) Query: 5 IEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMK-QYQEEIQELNEVARHRPRS 63 IEK + + ++ ++ H +++++ N ++ +K Q+ + + EL + Sbjct: 1677 IEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQ------ 1730 Query: 64 TLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGII 123 + + +E ++ LQQ +++ + +E + LE + + ++ R+ S+ + Sbjct: 1731 ---VAVLEEKLELENLQQISQQQKGEIEWQKQLLE----RDKREIERMTAESRALQSCVE 1783 Query: 124 MKLKEQHS---KIDMVHRNKSEGF-FLDASRHILEAPQHGLERRHLEANQNELQAHVDQI 179 KE+ K D+ + ++ L A+ + Q LE+ LE N +LQ +DQ+ Sbjct: 1784 CLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEK--LELNVRKLQQELDQL 1841 Query: 180 TEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDD---ASES 236 + I +QQ +++E + L++E +++ L + ++ L+ K SE Sbjct: 1842 NRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQ 1901 Query: 237 TSL 239 T L Sbjct: 1902 TRL 1904 Score = 32.7 bits (73), Expect = 0.31 Identities = 50/235 (21%), Positives = 93/235 (39%), Gaps = 15/235 (6%) Query: 7 KALADAKALVERLRDHD-DAAESLIEQTTALNKRVEAMKQYQEEIQELNEV-ARHRPRST 64 K L+ LV +LR D + +Q + + + +K Q I L+ +H Sbjct: 496 KQLSGRLQLVNKLRQEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKA 555 Query: 65 LVMGIQQE----NRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDP 120 G +Q+ N+Q ++L+ E+ + + + ++ + + E A KKD Sbjct: 556 QKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLE 615 Query: 121 GIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQIT 180 G+I L+E I K + L + L +R E Q Q + + Sbjct: 616 GVISGLQEYLGTI------KGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEI--VA 667 Query: 181 EMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDDASE 235 A MRK + + + +EQ + Q+ +G + E+ LNLR +A++ Sbjct: 668 MDAENMRKEL-AELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQ 721 Score = 30.4 bits (67), Expect = 1.5 Identities = 47/234 (20%), Positives = 95/234 (40%), Gaps = 40/234 (17%) Query: 6 EKALADAKALVERLRDHDDAAESLIEQ-TTALNKRVEAMKQYQEEIQELNEVAR------ 58 E+ ++ A ++ L+D ++ + ++ LN V+ + + +E ++E+ R Sbjct: 765 EQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGT 824 Query: 59 -----HRPRSTLVMGIQQENRQIREL-----------QQENKELRTSLEEHQSALELIMS 102 H P L + +Q E+ Q ++L+ + Q L Sbjct: 825 GEMNIHSPSDVLGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEMALQQEKLATGQE 884 Query: 103 KYREQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLER 162 ++R+ R L A D K QH + + ++E +L + +E Q GL Sbjct: 885 EFRQACERALEARMNFD-------KRQHEA--RIQQMENEIHYLQENLKSMEEIQ-GLTD 934 Query: 163 RHLEANQNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLRE 216 L+ E + + Q+ E+ +K +E K QE++F L++E K L++ Sbjct: 935 LQLQEADEEKERILAQLRELEK--KKKLE-----DAKSQEQVFGLDKELKKLKK 981 >gi|169208036 PREDICTED: similar to Golgin subfamily A member 8-like protein 1 isoform 2 [Homo sapiens] Length = 601 Score = 44.3 bits (103), Expect = 1e-04 Identities = 38/169 (22%), Positives = 81/169 (47%), Gaps = 20/169 (11%) Query: 69 IQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKE 128 I Q I+ L+Q+ K++ LEE + A + +++ R+L + + +++ Sbjct: 92 ISQLKNTIKSLKQQKKQVEHQLEEEKKA-----NNKKQKAKRVLEVQIQT-----LNIQK 141 Query: 129 QHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQITEMAAVMRK 188 + D+ H +S +F + S+ + QH L+R+ EL++ + + MA +K Sbjct: 142 EELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRK------GELESVLSNV--MATQKKK 193 Query: 189 AIEIDEQQGCKEQERIFQLEQENKGLREILQITRESF--LNLRKDDASE 235 A ++ + + + ++ Q +E L+ L +ESF + L +D+ SE Sbjct: 194 ANQLSSRSKARTEWKLEQSMREEALLKVQLTQLKESFQQVQLERDEYSE 242 >gi|239745147 PREDICTED: similar to Golgin subfamily A member 8-like protein 1 isoform 1 [Homo sapiens] Length = 630 Score = 44.3 bits (103), Expect = 1e-04 Identities = 38/169 (22%), Positives = 81/169 (47%), Gaps = 20/169 (11%) Query: 69 IQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKE 128 I Q I+ L+Q+ K++ LEE + A + +++ R+L + + +++ Sbjct: 93 ISQLKNTIKSLKQQKKQVEHQLEEEKKA-----NNKKQKAKRVLEVQIQT-----LNIQK 142 Query: 129 QHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQITEMAAVMRK 188 + D+ H +S +F + S+ + QH L+R+ EL++ + + MA +K Sbjct: 143 EELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRK------GELESVLSNV--MATQKKK 194 Query: 189 AIEIDEQQGCKEQERIFQLEQENKGLREILQITRESF--LNLRKDDASE 235 A ++ + + + ++ Q +E L+ L +ESF + L +D+ SE Sbjct: 195 ANQLSSRSKARTEWKLEQSMREEALLKVQLTQLKESFQQVQLERDEYSE 243 Score = 29.6 bits (65), Expect = 2.6 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 7/71 (9%) Query: 27 ESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKEL 86 E + EQ L K+ E +++ + +Q+L +P+S EN+ +L+Q+ KEL Sbjct: 341 ERIQEQEERLRKQEERIQEQHKSLQQLA-----KPQSVFEEP-NNENKNALQLEQQVKEL 394 Query: 87 RTSL-EEHQSA 96 + L EEH A Sbjct: 395 QEKLGEEHLEA 405 >gi|169208014 PREDICTED: Golgin subfamily A member 8-like protein 3 isoform 2 [Homo sapiens] Length = 602 Score = 43.9 bits (102), Expect = 1e-04 Identities = 38/169 (22%), Positives = 81/169 (47%), Gaps = 20/169 (11%) Query: 69 IQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKE 128 I Q I+ L+Q+ K++ LEE + A + +++ R+L + + +++ Sbjct: 92 ISQLKNTIKSLKQQKKQVEHQLEEEKKA-----NNKKQKAKRVLEVQIQT-----LNIQK 141 Query: 129 QHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQITEMAAVMRK 188 + D+ H +S +F + S+ + QH L+R+ EL++ + + MA +K Sbjct: 142 EELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRK------GELESVLSNV--MATQKKK 193 Query: 189 AIEIDEQQGCKEQERIFQLEQENKGLREILQITRESF--LNLRKDDASE 235 A ++ + + + ++ Q +E L+ L +ESF + L +D+ SE Sbjct: 194 ANQLSSRSKARTEWKLEQSMREEALLKVQLTQFKESFQQVQLERDEYSE 242 >gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein 3 isoform 1 [Homo sapiens] Length = 632 Score = 43.9 bits (102), Expect = 1e-04 Identities = 38/169 (22%), Positives = 81/169 (47%), Gaps = 20/169 (11%) Query: 69 IQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKE 128 I Q I+ L+Q+ K++ LEE + A + +++ R+L + + +++ Sbjct: 93 ISQLKNTIKSLKQQKKQVEHQLEEEKKA-----NNKKQKAKRVLEVQIQT-----LNIQK 142 Query: 129 QHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQITEMAAVMRK 188 + D+ H +S +F + S+ + QH L+R+ EL++ + + MA +K Sbjct: 143 EELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRK------GELESVLSNV--MATQKKK 194 Query: 189 AIEIDEQQGCKEQERIFQLEQENKGLREILQITRESF--LNLRKDDASE 235 A ++ + + + ++ Q +E L+ L +ESF + L +D+ SE Sbjct: 195 ANQLSSRSKARTEWKLEQSMREEALLKVQLTQFKESFQQVQLERDEYSE 243 Score = 29.6 bits (65), Expect = 2.6 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 7/71 (9%) Query: 27 ESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKEL 86 E + EQ L K+ E +++ + +Q+L +P+S EN+ +L+Q+ KEL Sbjct: 341 ERIREQEERLRKQEERIQEQHKSLQQLA-----KPQSVFKEP-NNENKNALQLEQQVKEL 394 Query: 87 RTSL-EEHQSA 96 + L EEH A Sbjct: 395 QEKLGEEHLEA 405 >gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] Length = 971 Score = 43.9 bits (102), Expect = 1e-04 Identities = 62/281 (22%), Positives = 116/281 (41%), Gaps = 43/281 (15%) Query: 5 IEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRST 64 +E L L + L +++ ++Q A + + ++ +E++EL E + R +S Sbjct: 570 VEDLLNQISLLKQNLEIQLSQSQTSLQQLQA--QFTQERQRLTQELEELEEQHQQRHKSL 627 Query: 65 LVMGIQQENRQIRELQQENKELRTSLEE-HQSALELIMSKYREQM--FRLLMASKK---- 117 + E ++E + L L++ H + L+ + +RE M FR+ M + Sbjct: 628 KEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLR 687 Query: 118 ---DDPGIIM------KLKEQHSK-IDMVHRNKSEGFF---------LDASR-----HIL 153 +D G M +L QH+ ID++ N + +D SR HI Sbjct: 688 FELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELAAAKMELERSIDISRRQSKEHIC 747 Query: 154 EAPQHGLERRHLEANQNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKG 213 E RH E + +EL V + E + + K +E K +E + + N+ Sbjct: 748 RITDLQEELRHREHHISELDKEVQHLHENISALTKELEF------KGKEILRIRSESNQQ 801 Query: 214 LREILQITRESFL--NLRKDDASESTSLSALVTNSDLSLRK 252 +R L+ E +L + +D T L A++T D ++K Sbjct: 802 IR--LEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKK 840 Score = 42.7 bits (99), Expect = 3e-04 Identities = 44/175 (25%), Positives = 85/175 (48%), Gaps = 18/175 (10%) Query: 70 QQENRQIRELQQE-NKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKE 128 +++ +QI EL+++ N+ RT E ++ L+ + S+ E++ +L A K + K Sbjct: 313 EEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELAWK--- 369 Query: 129 QHSKIDMVHRNKSEGFFLDASRHILEAP-QHGLERRHLEANQNELQAHVDQITEMAAVMR 187 H I+ VH N D + ++ QH ++ +LE ++N+LQ ++ + E V+ Sbjct: 370 HHMAIEAVHSNAIR----DKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKE---VLE 422 Query: 188 KAIEIDEQQGCKEQERIFQLEQ---ENKGLREILQITRESF---LNLRKDDASES 236 + Q+ Q+ + + EQ +GL LQ ++E L+L KD E+ Sbjct: 423 DKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKET 477 Score = 28.5 bits (62), Expect = 5.9 Identities = 38/204 (18%), Positives = 78/204 (38%), Gaps = 16/204 (7%) Query: 32 QTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQ---IRELQQENKELRT 88 + +LNK +E ++ ++++ E E ++ +S + R E Q +KE Sbjct: 106 EVESLNKMLEELRLERKKLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEA 165 Query: 89 SLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRN--------- 139 L + E I+ K ++ L + + ++ K ++ + + + N Sbjct: 166 DLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLD 225 Query: 140 -KSEGFFLDASRHILEAPQHGLERRHLEANQNEL---QAHVDQITEMAAVMRKAIEIDEQ 195 EG S+H + R L+ ++L +H+ + I+ E Sbjct: 226 DAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLES 285 Query: 196 QGCKEQERIFQLEQENKGLREILQ 219 + + ER+ QLE+E LR Q Sbjct: 286 EKSRVNERLSQLEEERAFLRSKTQ 309 >gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 [Homo sapiens] Length = 3259 Score = 43.9 bits (102), Expect = 1e-04 Identities = 59/259 (22%), Positives = 105/259 (40%), Gaps = 28/259 (10%) Query: 6 EKALADA-KALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRST 64 E+ +DA ++ E +R +D L +Q ++ +E +K ++ ++ + ++ Sbjct: 2212 ERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTE 2271 Query: 65 LVMGIQQENRQIRELQQENKELRTSLEE-----HQSALELIMSKYREQMFRLLMASKKDD 119 +Q + + LQ ENKEL + LEE H S EL E + L D Sbjct: 2272 ----VQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKL---ESELKSLKDQLTDL 2324 Query: 120 PGIIMKLKEQHSKIDMVHRNK-----SEGFFLDASRHILEAPQHGLERRHLEANQNE--- 171 + K KEQ ++ + R + + F + L+A + R H E N E Sbjct: 2325 SNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKI 2384 Query: 172 ---LQAHVDQITEMAAVMR----KAIEIDEQQGCKEQERIFQLEQENKGLREILQITRES 224 L + I A +R K I+ E +E+E LE+ENK + E+ Sbjct: 2385 ISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMET 2444 Query: 225 FLNLRKDDASESTSLSALV 243 ++K++ + L + V Sbjct: 2445 LKTIKKENIQQKAQLDSFV 2463 Score = 40.4 bits (93), Expect = 0.001 Identities = 59/281 (20%), Positives = 123/281 (43%), Gaps = 44/281 (15%) Query: 5 IEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEA-MKQYQEEIQELNEVARHRPRS 63 I++A A+ L E +R S ++ + N +++A + QY+E++ ++ + + + Sbjct: 2498 IQEAAAENNKLKEEIR----GLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQ 2553 Query: 64 TLVMGIQQ----ENR------QIRELQQENKELRTSL----EEHQS------ALELIMSK 103 L + +QQ EN+ +++E ++ N++LR S EE Q +L++ +S+ Sbjct: 2554 LLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQ 2613 Query: 104 YREQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGL--- 160 Q+ L +K+KE+ VHR + F + + I E + + Sbjct: 2614 LTRQVTALQEEGTLGLYHAQLKVKEEE-----VHRLSA--LFSSSQKRIAELEEELVCVQ 2666 Query: 161 --ERRHLEANQNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQ-------EN 211 + + +++L+ + + A +MR E E++ + + ++EQ EN Sbjct: 2667 KEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKEN 2726 Query: 212 KGLREILQITRESFLNLRKDDASESTSLSALVTNSDLSLRK 252 KGL +Q S +L+ + L L D SL++ Sbjct: 2727 KGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKE 2767 Score = 38.9 bits (89), Expect = 0.004 Identities = 51/227 (22%), Positives = 101/227 (44%), Gaps = 36/227 (15%) Query: 6 EKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTL 65 ++AL + K+L E L E L + + +V A + ++ + L Sbjct: 1493 KEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVL-----------GRL 1541 Query: 66 VMGIQQENRQIRELQQ---ENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGI 122 + ++ ++ I E+ + EN+ L +S E + ALE + ++ +E++ + + + K Sbjct: 1542 ALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGL-TEDKEKLVKEIESLKSSKIAE 1600 Query: 123 IMKLKEQHSKIDMVHR---NKSEGFFLDASR--HILEAPQHGLER-----RHLEANQNE- 171 + +E+H ++ + E +A R H++EA + + R EAN+ E Sbjct: 1601 STEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKET 1660 Query: 172 ---LQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLR 215 LQ ++ EM MRK + +Q++I +LE+EN LR Sbjct: 1661 EKQLQEAEQEMEEMKEKMRKFAK-------SKQQKILELEEENDRLR 1700 Score = 32.0 bits (71), Expect = 0.53 Identities = 43/226 (19%), Positives = 108/226 (47%), Gaps = 39/226 (17%) Query: 10 ADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGI 69 ++ K L + + + ++ + L+++ T + + K+Y E+IQ + ++ + + + Sbjct: 1956 SEMKNLKKCVSELEEEKQQLVKEKTKVESEIR--KEYLEKIQGAQKEPGNKSHAKELQEL 2013 Query: 70 QQENRQ-IRELQQE---NKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMK 125 +E +Q +++LQ++ +E ++LE ALE + ++ S+KD ++ Sbjct: 2014 LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTE-----------SQKD-----LE 2057 Query: 126 LKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLER---------RHLEANQNELQAHV 176 + +++ + HR K++ L + + +L+ Q R + L++N+ +++ + Sbjct: 2058 ITKENLAQAVEHRKKAQA-ELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQM 2116 Query: 177 DQITEMAAVMRKAIEIDEQQGCKE----QERIFQLEQENKGLREIL 218 Q E + + +E E++ KE QE++ L +E L E + Sbjct: 2117 KQKDE---DLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETI 2159 Score = 29.3 bits (64), Expect = 3.4 Identities = 52/257 (20%), Positives = 102/257 (39%), Gaps = 28/257 (10%) Query: 24 DAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQEN 83 D S I NKR + ++ +++ E +H+ S L++ +++ +I L+ + Sbjct: 521 DREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQL 580 Query: 84 KELRTSLEEHQSALELIMSKYR-EQMFRLLMASKKDDPG-----------IIMKLKEQHS 131 + R +H+ + M + E + + M +D G + ++++ + Sbjct: 581 QGKRAEEADHEVLDQKEMKQMEGEGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQA 640 Query: 132 KIDMVHRNKSEGFFLDASRHILEAPQHGLERRHL-----EANQNELQAHVDQITEMAAVM 186 + R E DA + Q G + + +Q+EL+ QI E+ Sbjct: 641 STEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNF 700 Query: 187 RKAIEIDEQ---QGCKEQERIFQLEQE-------NKGLREILQITRESFLNLRKDDASES 236 KA EI E+ + KE + QL +E N L R+ L+ K + S Sbjct: 701 HKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVK-ELSMV 759 Query: 237 TSLSALVTNSDLSLRKS 253 T L A V +++L ++ Sbjct: 760 TELRAQVKQLEMNLAEA 776 Score = 29.3 bits (64), Expect = 3.4 Identities = 26/106 (24%), Positives = 48/106 (45%), Gaps = 14/106 (13%) Query: 15 LVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENR 74 +VE +R + T A K E KQ QE QE+ E+ + + + + Sbjct: 1635 VVEAVRQEKQELYGKLRSTEANKKETE--KQLQEAEQEMEEMKEKMRKFA-----KSKQQ 1687 Query: 75 QIRELQQENKELRTSL----EEHQSALELIMS---KYREQMFRLLM 113 +I EL++EN LR + + + +E ++S +E++ R+ M Sbjct: 1688 KILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKM 1733 >gi|239745132 PREDICTED: similar to Golgin subfamily A member 8-like protein 1 [Homo sapiens] Length = 602 Score = 43.5 bits (101), Expect = 2e-04 Identities = 41/171 (23%), Positives = 80/171 (46%), Gaps = 24/171 (14%) Query: 69 IQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKE 128 I Q I+ L+Q+ K++ LEE + A + +++ R+L I L Sbjct: 92 ISQLKNTIKSLKQQKKQVEHQLEEEKKA-----NNKKQKAKRVLEVQ-------IQTLNI 139 Query: 129 QHSKI--DMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQITEMAAVM 186 Q K+ D+ H +S +F + S+ + QH L+R+ EL++ + + MA Sbjct: 140 QKGKLNTDLYHMKRSLRYFEEKSKDLAVCLQHSLQRK------GELESVLSNV--MATQK 191 Query: 187 RKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESF--LNLRKDDASE 235 +KA ++ + + + ++ Q +E L+ L +ESF + L +D+ +E Sbjct: 192 KKANQLSSRSKARTEWKLEQSMREEALLKVQLTQLKESFQQVQLERDECAE 242 >gi|239745130 PREDICTED: similar to Golgin subfamily A member 8-like protein 1 isoform 1 [Homo sapiens] Length = 632 Score = 43.5 bits (101), Expect = 2e-04 Identities = 41/171 (23%), Positives = 80/171 (46%), Gaps = 24/171 (14%) Query: 69 IQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKE 128 I Q I+ L+Q+ K++ LEE + A + +++ R+L I L Sbjct: 93 ISQLKNTIKSLKQQKKQVEHQLEEEKKA-----NNKKQKAKRVLEVQ-------IQTLNI 140 Query: 129 QHSKI--DMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQITEMAAVM 186 Q K+ D+ H +S +F + S+ + QH L+R+ EL++ + + MA Sbjct: 141 QKGKLNTDLYHMKRSLRYFEEKSKDLAVCLQHSLQRK------GELESVLSNV--MATQK 192 Query: 187 RKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESF--LNLRKDDASE 235 +KA ++ + + + ++ Q +E L+ L +ESF + L +D+ +E Sbjct: 193 KKANQLSSRSKARTEWKLEQSMREEALLKVQLTQLKESFQQVQLERDECAE 243 Score = 29.6 bits (65), Expect = 2.6 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 7/71 (9%) Query: 27 ESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKEL 86 E + EQ L K+ E +++ + +Q+L +P+S EN+ +L+Q+ KEL Sbjct: 341 ERIQEQEERLRKQEERIQEQHKSLQQLA-----KPQSVFEEP-NNENKNALQLEQQVKEL 394 Query: 87 RTSL-EEHQSA 96 + L EEH A Sbjct: 395 QEKLGEEHLEA 405 >gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo sapiens] Length = 1591 Score = 43.1 bits (100), Expect = 2e-04 Identities = 59/240 (24%), Positives = 111/240 (46%), Gaps = 44/240 (18%) Query: 6 EKALADAKALVERLRDHDDAAESLIEQTTALNKRVE-AMKQYQ-EEIQELNEVARHRPRS 63 EK L + K V L D T VE A+K+ + +EI+ L E +R + + Sbjct: 1040 EKQLQELKLKVSDLSD------------TRCKLEVELALKEAETDEIKILLEESRAQQKE 1087 Query: 64 TLVMGIQQENRQIR-ELQQENKELRTSLEEHQ---SALELIMSKYREQMFRLLMASKKDD 119 TL ++QE +R E+ + N++++ + E +Q + L +M+ ++Q L++ +++ Sbjct: 1088 TLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEE 1147 Query: 120 PGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQI 179 I LK + +K+ +H E ++L+ ELQ+ +D Sbjct: 1148 SNI---LKAELNKVTSLHNQAFE------------------IEKNLKEQIIELQSKLD-- 1184 Query: 180 TEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESF---LNLRKDDASES 236 +E++A+ R+ E QQ K + I LE++ + L + RE LN KD+A ++ Sbjct: 1185 SELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQT 1244 >gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo sapiens] Length = 1594 Score = 43.1 bits (100), Expect = 2e-04 Identities = 59/240 (24%), Positives = 111/240 (46%), Gaps = 44/240 (18%) Query: 6 EKALADAKALVERLRDHDDAAESLIEQTTALNKRVE-AMKQYQ-EEIQELNEVARHRPRS 63 EK L + K V L D T VE A+K+ + +EI+ L E +R + + Sbjct: 1040 EKQLQELKLKVSDLSD------------TRCKLEVELALKEAETDEIKILLEESRAQQKE 1087 Query: 64 TLVMGIQQENRQIR-ELQQENKELRTSLEEHQ---SALELIMSKYREQMFRLLMASKKDD 119 TL ++QE +R E+ + N++++ + E +Q + L +M+ ++Q L++ +++ Sbjct: 1088 TLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEE 1147 Query: 120 PGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQI 179 I LK + +K+ +H E ++L+ ELQ+ +D Sbjct: 1148 SNI---LKAELNKVTSLHNQAFE------------------IEKNLKEQIIELQSKLD-- 1184 Query: 180 TEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESF---LNLRKDDASES 236 +E++A+ R+ E QQ K + I LE++ + L + RE LN KD+A ++ Sbjct: 1185 SELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQT 1244 >gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] Length = 495 Score = 43.1 bits (100), Expect = 2e-04 Identities = 38/169 (22%), Positives = 78/169 (46%), Gaps = 10/169 (5%) Query: 17 ERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQI 76 +R+ + E ++ AL +++E M + +E+++++ + ++ + +E + Sbjct: 283 DRMAKVQENEEKRLQLQNALTQKLEEMLRQREDLEQVRQELYQEEQAEIYKSKLKEEAEK 342 Query: 77 RELQQENKELRTSLEEHQSALELIM--SKYREQMFRLLMASK--KDDPGIIMKLKEQHSK 132 + +Q KE++ EE + EL++ +K E+ FR M +K +DD +M ++Q K Sbjct: 343 KLRKQ--KEMKQDFEEQMALKELVLQAAKEEEENFRKTMLAKFAEDDRIELMNAQKQRMK 400 Query: 133 IDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQITE 181 + HR E + + L Q LE L Q Q ++ I E Sbjct: 401 -QLEHRRAVEKLIEERRQQFLADKQRELEEWQL---QQRRQGFINAIIE 445 >gi|88196790 coiled-coil domain containing 88 [Homo sapiens] Length = 1476 Score = 43.1 bits (100), Expect = 2e-04 Identities = 62/241 (25%), Positives = 106/241 (43%), Gaps = 52/241 (21%) Query: 9 LADAKALVERLRDH-DDAAESLIE-----------------QTTALNKRVEAMKQYQEEI 50 LA+AKA + RLR ++ AE L++ + AL+ + + + Y+EE Sbjct: 260 LANAKAQLRRLRQELEEKAELLLDSQAEVQGLEAEIRRLRQEAQALSGQAKRAELYREEA 319 Query: 51 QELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQ----------SALELI 100 + L E A PR +Q+E R+ RE Q + ++ LEE + + LE Sbjct: 320 EALRERAGRLPR------LQEELRRCRERLQAAEAYKSQLEEERVLSGVLEASKALLEEQ 373 Query: 101 MSKYREQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGL 160 + RE+ RL +++++ + +L E H++ LD+ RH + Q Sbjct: 374 LEAARERCARL-HETQRENLLLRTRLGEAHAE-------------LDSLRH--QVDQLAE 417 Query: 161 ERRHLEAN-QNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQ 219 E LE Q L+ E A + A + ++ E R+ LE+EN+ LR +LQ Sbjct: 418 ENVELELELQRSLEPPPGSPGE-APLAGAAPSLQDEVREAEAGRLRTLERENRELRGLLQ 476 Query: 220 I 220 + Sbjct: 477 V 477 Score = 33.9 bits (76), Expect = 0.14 Identities = 50/222 (22%), Positives = 104/222 (46%), Gaps = 22/222 (9%) Query: 4 TIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEI-QELNEVARHRPR 62 ++ +A+ +AL E + AE+L ++ A +++EA + +EL + R Sbjct: 719 SLASGVAEQEALREEVAQLRRKAEALGDELEAQARKLEAQNTEAARLSKELAQARRAEAE 778 Query: 63 STLVMGIQQ-ENRQIRE-LQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDP 120 + Q E ++RE ++ +EL ++ +E ++ +E + + RE+ + + Sbjct: 779 AHREAEAQAWEQARLREAVEAAGQELESASQEREALVEALAAAGRERR-------QWERE 831 Query: 121 GIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQIT 180 G ++ + + ++ + + +SEG +H+ EA + ERR EA Q EL+ V + Sbjct: 832 GSRLRAQSEAAE-ERMQVLESEG-----RQHLEEAER---ERREKEALQAELEKAVVRGK 882 Query: 181 EMAAVMRKAIEIDEQQGCKEQERIFQLE---QENKGLREILQ 219 E+ A + EQ + QE + + E Q +GL + L+ Sbjct: 883 ELGARLEHLQRELEQAALERQEFLREKESQHQRYQGLEQRLE 924 Score = 32.0 bits (71), Expect = 0.53 Identities = 47/228 (20%), Positives = 97/228 (42%), Gaps = 26/228 (11%) Query: 9 LADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQ-------------ELNE 55 L D KAL + R + E L+ + L + A++ E+Q E E Sbjct: 1075 LRDHKALAQLQRRQEAELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRASVEAQE 1134 Query: 56 VARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMAS 115 VA R L+ Q+ + R L++E + L++ EH A L+ RE+ L Sbjct: 1135 VALLAERERLM----QDGHRQRGLEEELRRLQS---EHDRAQMLLAELSRER--GELQGE 1185 Query: 116 KKDDPGIIMKLKEQHSKIDMVH---RNKSEGFFLDASRHILEAPQHGLERRHLEANQNEL 172 + + G + +L+ + ++++M R ++ L A R + R E +L Sbjct: 1186 RGELRGRLARLELERAQLEMQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENRQL 1245 Query: 173 QAHVDQIT-EMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQ 219 A V ++ E ++ +++E + +++E + QL + +++++ Sbjct: 1246 LAEVQALSRENRELLERSLESRDHLHREQREYLDQLNALRREKQKLVE 1293 Score = 31.6 bits (70), Expect = 0.69 Identities = 35/167 (20%), Positives = 64/167 (38%), Gaps = 14/167 (8%) Query: 65 LVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIM 124 L++ Q+ LQ E L +E LE++ E+ R S+++ G Sbjct: 1018 LLLQSQRAQEHSSRLQAEKSVLEIQGQELHRKLEVL-----EEEVRAARQSQEETRGQQQ 1072 Query: 125 KLKEQHSKIDMVHRNKS---EGFF-----LDASRHILEAPQHGLERRHLEANQNELQAHV 176 L H + + R + EG L A+ LE L+ RH + Sbjct: 1073 ALLRDHKALAQLQRRQEAELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRASVEA 1132 Query: 177 DQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRE 223 ++ +A R + Q+G +E+ R Q E + + + +++RE Sbjct: 1133 QEVALLAERERLMQDGHRQRGLEEELRRLQSEHDRAQML-LAELSRE 1178 >gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 42.7 bits (99), Expect = 3e-04 Identities = 63/277 (22%), Positives = 120/277 (43%), Gaps = 44/277 (15%) Query: 5 IEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNE-VARHRPRS 63 +E + +A++L L +A E ++Q L + K Q+EI +L E +A R Sbjct: 1473 LEASQKEARSLGTELFKIKNAYEESLDQLETLKRE---NKNLQQEISDLTEQIAEGGKR- 1528 Query: 64 TLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGII 123 I + + ++++QE EL+ +LEE +++LE K + R+ + + + Sbjct: 1529 -----IHELEKIKKQVEQEKCELQAALEEAEASLEHEEGK----ILRIQLELNQVKSEVD 1579 Query: 124 MKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLE-----RRHLEANQNELQAHVDQ 178 K+ E+ +ID + RN +++ + L+A ++ +E + NE++ ++ Sbjct: 1580 RKIAEKDEEIDQLKRNHIR--IVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNH 1637 Query: 179 ITEMAA------------VMRKAIEIDE----QQGCKEQ-----ERIFQLEQENKGLREI 217 MAA + I +D+ Q+ KEQ R L+ E + LR Sbjct: 1638 ANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRAT 1697 Query: 218 LQITRESFLNLRKD--DASESTSLSALVTNSDLSLRK 252 L+ T S ++ DASE L S ++ +K Sbjct: 1698 LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKK 1734 Score = 38.9 bits (89), Expect = 0.004 Identities = 46/209 (22%), Positives = 85/209 (40%), Gaps = 8/209 (3%) Query: 23 DDAA---ESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIREL 79 DDA E L EQ + +R + Q EI+EL RS + +QE E Sbjct: 1664 DDALRSQEDLKEQLAMVERRANLL---QAEIEELRATLEQTERSRKIA--EQELLDASER 1718 Query: 80 QQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRN 139 Q TSL + LE +S+ + +M +L ++ + + + + + + Sbjct: 1719 VQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKE 1778 Query: 140 KSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQITEMAAVMRKAIEIDEQQGCK 199 + L+ + +E L+ R EA Q L+ QI ++ A +R+ E + + Sbjct: 1779 QDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKR 1838 Query: 200 EQERIFQLEQENKGLREILQITRESFLNL 228 E + L + + ++E+ T E N+ Sbjct: 1839 NAEAVKGLRKHERRVKELTYQTEEDRKNI 1867 Score = 28.1 bits (61), Expect = 7.7 Identities = 19/106 (17%), Positives = 45/106 (42%), Gaps = 3/106 (2%) Query: 5 IEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMK-QYQEEIQELNEVARH--RP 61 +EK + + L+ ++ + LI TA R++ ++ ++ E + R Sbjct: 1251 LEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRG 1310 Query: 62 RSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQ 107 + I++ RQ+ E + L +L+ + +L+ +Y E+ Sbjct: 1311 KQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEE 1356 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.127 0.331 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,646,667 Number of Sequences: 37866 Number of extensions: 305852 Number of successful extensions: 3315 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 110 Number of HSP's successfully gapped in prelim test: 488 Number of HSP's that attempted gapping in prelim test: 2188 Number of HSP's gapped (non-prelim): 1361 length of query: 253 length of database: 18,247,518 effective HSP length: 100 effective length of query: 153 effective length of database: 14,460,918 effective search space: 2212520454 effective search space used: 2212520454 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.