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Search of human proteins with 24308075
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308075 RAB11 family interacting protein 5 (class I) [Homo
sapiens]
(653 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308075 RAB11 family interacting protein 5 (class I) [Homo s... 1288 0.0
gi|50363228 RAB11 family interacting protein 1 isoform 1 [Homo s... 311 1e-84
gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo s... 265 1e-70
gi|7662394 RAB11 family interacting protein 2 (class I) [Homo sa... 198 1e-50
gi|50363230 RAB11 family interacting protein 1 isoform 2 [Homo s... 72 2e-12
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 48 3e-05
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 47 6e-05
gi|222537747 hypothetical protein LOC342979 [Homo sapiens] 42 0.002
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 42 0.002
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 41 0.004
gi|28460688 taxilin [Homo sapiens] 40 0.007
gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo... 40 0.007
gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Hom... 40 0.007
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] 39 0.012
gi|42518068 trans-golgi network protein 2 [Homo sapiens] 39 0.015
gi|60097902 filaggrin [Homo sapiens] 39 0.020
gi|214010165 rab11-family interacting protein 3 isoform 2 [Homo ... 37 0.044
gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo sa... 37 0.044
gi|56699475 zinc finger protein 202 [Homo sapiens] 37 0.044
gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo sapi... 37 0.057
gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo sapi... 37 0.057
gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B ... 37 0.075
gi|122937247 unc-13 homolog A [Homo sapiens] 37 0.075
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 37 0.075
gi|122937514 unc-13 homolog C [Homo sapiens] 36 0.098
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 36 0.098
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 36 0.098
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 36 0.098
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 36 0.13
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 36 0.13
>gi|24308075 RAB11 family interacting protein 5 (class I) [Homo
sapiens]
Length = 653
Score = 1288 bits (3333), Expect = 0.0
Identities = 653/653 (100%), Positives = 653/653 (100%)
Query: 1 MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV 60
MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV
Sbjct: 1 MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV 60
Query: 61 EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV 120
EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV
Sbjct: 61 EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV 120
Query: 121 DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL 180
DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL
Sbjct: 121 DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL 180
Query: 181 SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL 240
SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL
Sbjct: 181 SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL 240
Query: 241 RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF 300
RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF
Sbjct: 241 RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF 300
Query: 301 THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG 360
THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG
Sbjct: 301 THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG 360
Query: 361 SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP 420
SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP
Sbjct: 361 SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP 420
Query: 421 GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR 480
GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR
Sbjct: 421 GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR 480
Query: 481 SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHPVKPLSAAPVEGSPD 540
SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHPVKPLSAAPVEGSPD
Sbjct: 481 SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHPVKPLSAAPVEGSPD 540
Query: 541 RKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSAVLDQSAKYYHL 600
RKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSAVLDQSAKYYHL
Sbjct: 541 RKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSAVLDQSAKYYHL 600
Query: 601 THDELISLLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQIPPGPPK 653
THDELISLLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQIPPGPPK
Sbjct: 601 THDELISLLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQIPPGPPK 653
>gi|50363228 RAB11 family interacting protein 1 isoform 1 [Homo
sapiens]
Length = 649
Score = 311 bits (797), Expect = 1e-84
Identities = 238/669 (35%), Positives = 339/669 (50%), Gaps = 80/669 (11%)
Query: 16 WLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVEKTHGCPEWREECSF 75
W PTHVQVTVL+ARGLR K G G TSDAY VIQVG+EKY+TSV E++ G P WREE +F
Sbjct: 15 WSPTHVQVTVLQARGLRAK--GPGGTSDAYAVIQVGKEKYATSVSERSLGAPVWREEATF 72
Query: 76 ELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGVDKFLGQATVALDEVF 135
ELP LL +GPA AA L LT +HR+L+G+DKFLG+A V L ++
Sbjct: 73 ELP-----SLL-----SSGPA-------AAATLQLTVLHRALLGLDKFLGRAEVDLRDLH 115
Query: 136 GAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDLSMKDKPRSPFSKIRD 195
+ TQWYKL SKPGKK+KERGEIEV IQF RNN++ASMFDLSMKDK R+PF K++D
Sbjct: 116 RDQGRRKTQWYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKD 175
Query: 196 KMKGKKK-YDLESASAILPSSAIE-DPDLGSLGKMGKAKGFFLRNKLRKSSLTQSNTSLG 253
K+KGK K ++ASAI+PS+ D D S+ K K K ++ L KS+L +
Sbjct: 176 KIKGKNKDSGSDTASAIIPSTTPSVDSDDESVVK-DKKKKSKIKTLLSKSNLQK------ 228
Query: 254 SDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLFTHKRTYSDEANQM 313
+ LS + L P LL +S W + +S+ + + +HKRT S + Q+
Sbjct: 229 --TPLSQSMSVLPTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQL 286
Query: 314 R----VAPPRALLDLQGHL----DAASRSSLCVNGSHIYNEEPQGPVRHRSSISGSLPSS 365
P + L G L D SRS++C+NG+H+Y E+P+ + S S PS
Sbjct: 287 NQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSP 346
Query: 366 GSLQAVSSRFSEEGPRSTDDTWPRGSRSNS-SSEAVLGQEELSAQAKVLAPGASHPGEEE 424
+ S E + +W + SS+ L + K + + P
Sbjct: 347 KGFRKKHLFSSTENLAA--GSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRP---- 400
Query: 425 GARLPEGKPVQVATPIVASSEAVAE-KEGARKEERKPRMGLFHHHHQGLSRSELGRRSSL 483
A L G + P A+SEA E KE + E R+ + + +++ G
Sbjct: 401 -APLVSGDLRENMAP--ANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLT 457
Query: 484 ---GEKGGPILGASPHHSSSGEEK---------------AKSSWFGLREAKDPTQKPSPH 525
EK G ++G P +SG + + S L E T+ P
Sbjct: 458 VPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITE-PEAE 516
Query: 526 PVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRL 585
P P SP Q+R A+ L +K + + + + V + ++ L
Sbjct: 517 PESKSEPRPPISSPRAPQTR-----AVKPRLHPVKPMNATATK-VANCSLGTATIISENL 570
Query: 586 KDSAVL------DQSAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIME 639
+ ++ D + Y LTHDELI L+L+++ +S+++ V+ELE YID LLVR+ME
Sbjct: 571 NNEVMMKKYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVME 630
Query: 640 TSPTLLQIP 648
+P +L+IP
Sbjct: 631 ETPNILRIP 639
>gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo
sapiens]
Length = 1283
Score = 265 bits (676), Expect = 1e-70
Identities = 193/501 (38%), Positives = 264/501 (52%), Gaps = 52/501 (10%)
Query: 16 WLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVEKTHGCPEWREECSF 75
W PTHVQVTVL+ARGLR K G G TSDAY VIQVG+EKY+TSV E++ G P WREE +F
Sbjct: 15 WSPTHVQVTVLQARGLRAK--GPGGTSDAYAVIQVGKEKYATSVSERSLGAPVWREEATF 72
Query: 76 ELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGVDKFLGQATVALDEVF 135
ELP LL +GPA AA L LT +HR+L+G+DKFLG+A V L ++
Sbjct: 73 ELP-----SLL-----SSGPA-------AAATLQLTVLHRALLGLDKFLGRAEVDLRDLH 115
Query: 136 GAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDLSMKDKPRSPFSKIRD 195
+ TQWYKL SKPGKK+KERGEIEV IQF RNN++ASMFDLSMKDK R+PF K++D
Sbjct: 116 RDQGRRKTQWYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKD 175
Query: 196 KMKGKKK-YDLESASAILPSSAIE-DPDLGSLGKMGKAKGFFLRNKLRKSSLTQSNTSLG 253
K+KGK K ++ASAI+PS+ D D S+ K K K ++ L KS+L +
Sbjct: 176 KIKGKNKDSGSDTASAIIPSTTPSVDSDDESVVK-DKKKKSKIKTLLSKSNLQK------ 228
Query: 254 SDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLFTHKRTYSDEANQM 313
+ LS + L P LL +S W + +S+ + + +HKRT S + Q+
Sbjct: 229 --TPLSQSMSVLPTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQL 286
Query: 314 R----VAPPRALLDLQGHL----DAASRSSLCVNGSHIYNEEPQGPVRHRSSISGSLPSS 365
P + L G L D SRS++C+NG+H+Y E+P+ + S S PS
Sbjct: 287 NQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSP 346
Query: 366 GSLQAVSSRFSEEGPRSTDDTWPRGSRSNS-SSEAVLGQEELSAQAKVLAPGASHPGEEE 424
+ S E + +W + SS+ L + K + + P
Sbjct: 347 KGFRKKHLFSSTENLAA--GSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRP---- 400
Query: 425 GARLPEGKPVQVATPIVASSEAVAE-KEGARKEERKPRMGLFHHHHQGLSRSELGRRSSL 483
A L G + P A+SEA E KE + E R+ + + +++ G
Sbjct: 401 -APLVSGDLRENMAP--ANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLT 457
Query: 484 ---GEKGGPILGASPHHSSSG 501
EK G ++G P +SG
Sbjct: 458 VPGREKEGMLMGVKPGEDASG 478
Score = 72.0 bits (175), Expect = 2e-12
Identities = 49/161 (30%), Positives = 85/161 (52%), Gaps = 14/161 (8%)
Query: 496 HHSSSGEEKAKSSWFGL--REAKDPTQKP------SPHPVKPLSAAPVEGSPDRKQSRSS 547
HH+S+ E + K++ G R +KP SP P+SA P G+ K
Sbjct: 1119 HHTSTAESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPGAGTGSAKHRLHP 1178
Query: 548 LSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSAVLDQSAKYYHLTHDELIS 607
+ +++ K+ + G+ +++ + + +K + D + Y LTHDELI
Sbjct: 1179 VK-PMNATATKVANCSLGTATIISE-----NLNNEVMMKKYSPSDPAFAYAQLTHDELIQ 1232
Query: 608 LLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQIP 648
L+L+++ +S+++ V+ELE YID LLVR+ME +P +L+IP
Sbjct: 1233 LVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRIP 1273
>gi|7662394 RAB11 family interacting protein 2 (class I) [Homo
sapiens]
Length = 512
Score = 198 bits (504), Expect = 1e-50
Identities = 129/315 (40%), Positives = 177/315 (56%), Gaps = 38/315 (12%)
Query: 15 RWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVEKTHGCPEWREECS 74
+W PTHVQVTVL+A+ L+ K G T+D YT+IQ+G+EKYSTSV EKT P W+EE S
Sbjct: 9 KWFPTHVQVTVLQAKDLKPK--GKSGTNDTYTIIQLGKEKYSTSVAEKTLE-PVWKEEAS 65
Query: 75 FELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGVDKFLGQATVALDEV 134
FELP + G S L L MHRSL+G+DKFLGQ + L+++
Sbjct: 66 FELPGLLIQG-----------------SPEKYILFLIVMHRSLVGLDKFLGQVAINLNDI 108
Query: 135 FGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDLSMKDKPRSPFSKIR 194
F + + T+W++L SK GK+ K RGEI+V IQF RNN++ASMFDLSMKDK RSPF+K++
Sbjct: 109 FEDKQRRKTEWFRLESKQGKRIKNRGEIKVNIQFMRNNMTASMFDLSMKDKTRSPFAKLK 168
Query: 195 DKMKGKKKYDL--ESASAILPSSAIEDPD----LGSLGKMGKAKGFFLRNKLRKSSLTQS 248
DKMKG+K +++SAI+PS+ + D + G + K K FL R SS
Sbjct: 169 DKMKGRKNDGTFSDTSSAIIPSTHMPDANSEFSSGEIQMKSKPKKPFLLGPQRLSSAHSM 228
Query: 249 NTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLFTHKRTYSD 308
+ GS + Q LL + G S +SP H+RT S
Sbjct: 229 SDLSGSHMSSEKLKAGTIGQ---THLLGHQLDSFGTVPESG---SLKSP----HRRTLSF 278
Query: 309 EANQMRVAPPRALLD 323
+ ++M P +++D
Sbjct: 279 DTSKMN--QPDSIVD 291
Score = 67.0 bits (162), Expect = 5e-11
Identities = 29/73 (39%), Positives = 51/73 (69%)
Query: 581 DTKRLKDSAVLDQSAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIMET 640
D +++ DS D +A Y LT++E++ L++ + L ++D H++ELE YID LLVR+ME
Sbjct: 432 DLRKIPDSNPFDATAGYRSLTYEEVLQELVKHKELLRRKDTHIRELEDYIDNLLVRVMEE 491
Query: 641 SPTLLQIPPGPPK 653
+P++L++P P +
Sbjct: 492 TPSILRVPYEPSR 504
>gi|50363230 RAB11 family interacting protein 1 isoform 2 [Homo
sapiens]
Length = 612
Score = 71.6 bits (174), Expect = 2e-12
Identities = 49/161 (30%), Positives = 85/161 (52%), Gaps = 14/161 (8%)
Query: 496 HHSSSGEEKAKSSWFGL--REAKDPTQKP------SPHPVKPLSAAPVEGSPDRKQSRSS 547
HH+S+ E + K++ G R +KP SP P+SA P G+ K
Sbjct: 448 HHTSTAESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPGAGTGSAKHRLHP 507
Query: 548 LSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSAVLDQSAKYYHLTHDELIS 607
+ +++ K+ + G+ +++ + + +K + D + Y LTHDELI
Sbjct: 508 VK-PMNAMATKVANCSLGTATIISE-----NLNNEVMMKKYSPSDPAFAYAQLTHDELIQ 561
Query: 608 LLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQIP 648
L+L+++ +S+++ V+ELE YID LLVR+ME +P +L+IP
Sbjct: 562 LVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRIP 602
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 47.8 bits (112), Expect = 3e-05
Identities = 83/370 (22%), Positives = 148/370 (40%), Gaps = 44/370 (11%)
Query: 227 KMGKAKGFFLRNKLRKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSP------- 279
K +A K SS + S++S DS A+ + P +++ ++P
Sbjct: 201 KPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTP 260
Query: 280 SRSSWLSTEGGRDSAQSPK--LFTHKRTYSD--------EANQMRVAPPRALLDLQGHLD 329
+R S S + D + K + YS + PP+ ++ Q ++
Sbjct: 261 TRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVE 320
Query: 330 AASRSSLCVNGSHIYNEEPQGPVRHRSSISGSLPSSGSLQAVSSRFSEEGPRSTDD---T 386
++ SS + S EE + P + S + + P A SS S + S DD +
Sbjct: 321 SSEDSSDESDSSS--EEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPS 378
Query: 387 WPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHPGEEEGARLPEGKPVQVATPIVASSEA 446
P G+ NSS++ + + ++ + P A+ + P G ++ T SS +
Sbjct: 379 KPAGTTKNSSNKPAV-----TTKSPAVKPAAA-------PKQPVGGGQKLLTRKADSSSS 426
Query: 447 VAEKEGARKEERKPRMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKAK 506
E+E + EE K + + + +++ L + +G + SSS EE+ K
Sbjct: 427 --EEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEK 484
Query: 507 SSWFGLREAKDPTQKPSPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGS 566
+S +++ K P KP SA + +S +S S SS E+ K GS
Sbjct: 485 TSKSAVKK-KPQKVAGGAAPSKPASA-----KKGKAESSNSSSSDDSSEEEEEKLKGKGS 538
Query: 567 IQPVTQAPQA 576
+P QAP+A
Sbjct: 539 PRP--QAPKA 546
Score = 33.9 bits (76), Expect = 0.48
Identities = 57/281 (20%), Positives = 98/281 (34%), Gaps = 62/281 (22%)
Query: 348 PQGPVRHRSSISGSLPSSGSLQAVSSRFSEEGPRSTDDTWPRGS---------------- 391
P P R I+ +S S + SS S++ P+ +
Sbjct: 199 PPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAAT 258
Query: 392 ---RSNSSSEAVLGQEELSAQ----------AKVLAPGASHPGEEEGARLPEGKPVQVAT 438
R +SSSE EE + + V P A P + G + P+ K V+
Sbjct: 259 TPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPK-KAVEKQQ 317
Query: 439 PIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASPHHS 498
P+ +S ++ E + + +EE+KP S+ + +K S
Sbjct: 318 PVESSEDSSDESDSSSEEEKKPPTKAV--------VSKATTKPPPAKKAAESSSDSSDSD 369
Query: 499 SSGEEKAKSSWFGLRE---------AKDPTQKPSPHPVKPL------------SAAPVEG 537
SS +++A S G + K P KP+ P +P+ S++ E
Sbjct: 370 SSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEE 429
Query: 538 SPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQ 578
S ++ ++ +A + K S P QAPQ +
Sbjct: 430 SSSSEEEKTKKMVATTKPKATAKAALS---LPAKQAPQGSR 467
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 47.0 bits (110), Expect = 6e-05
Identities = 53/207 (25%), Positives = 84/207 (40%), Gaps = 14/207 (6%)
Query: 254 SDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLFTHKRTYSDEANQM 313
S+S+ SS+SGS + + S S SS TEG + ++ + A
Sbjct: 2557 SESSSSSSSGSSS---------SSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASS 2607
Query: 314 RVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISGSLPSSGSLQAVSS 373
R A P + ++S SS + S + SS S S SS S + SS
Sbjct: 2608 RAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2667
Query: 374 RFS----EEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHPGEEEGARLP 429
S E+ S+DD + S++A L + + QA P A PG++ A P
Sbjct: 2668 SSSSTTDEDSSCSSDDEAAPAPTAGPSAQAAL-PTKATKQAGKARPSAHSPGKKTPAPQP 2726
Query: 430 EGKPVQVATPIVASSEAVAEKEGARKE 456
+ P Q P+ ++A A+ ++E
Sbjct: 2727 QAPPPQPTQPLQPKAQAGAKSRPKKRE 2753
Score = 35.4 bits (80), Expect = 0.17
Identities = 58/237 (24%), Positives = 84/237 (35%), Gaps = 51/237 (21%)
Query: 355 RSSISGSLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLA 414
RSS S S S S EE +D EA G L A+ + L+
Sbjct: 1810 RSSFSDSSEESFDQDESSEEEDEEEELEEED------------EASGGGYRLGARERALS 1857
Query: 415 PGASHPGEEEGARLPEGK-PVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLS 473
PG G AR P P ++ + A+++ +KEER+ +G + S
Sbjct: 1858 PGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSES 1917
Query: 474 RSELGRRSSLG----EKG----GPILGA-----------SPHHSSSGEEKAKSSWFGLRE 514
++ +RS G +KG GP L A SP + EK + + LR
Sbjct: 1918 EVKVRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKA-RKLRG 1976
Query: 515 AKDPTQKPSP------------------HPVKPLSAAPVEGSPDRKQSRSSLSIALS 553
K+P + P H + APV +P K SR + LS
Sbjct: 1977 PKEPGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVSTAPATKTSRCAKGGPLS 2033
Score = 33.5 bits (75), Expect = 0.63
Identities = 42/228 (18%), Positives = 75/228 (32%), Gaps = 6/228 (2%)
Query: 347 EPQGPVRHRSSISGSLPSSGSLQAVSSRFSE-----EGPRSTDDTWPRGSRSNSSSEAVL 401
E G SS S S SS S + SS SE EG ++ D G R+ S++ +
Sbjct: 2550 EQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRA 2609
Query: 402 GQEELSAQAKVLAPGASHPGEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPR 461
S+ + + +S + ++ +SS + + +
Sbjct: 2610 ASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2669
Query: 462 MGLFHHHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQK 521
S E + G L +G+ + + G + Q
Sbjct: 2670 SSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKAT-KQAGKARPSAHSPGKKTPAPQPQA 2728
Query: 522 PSPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQP 569
P P P +PL G+ R + R + + + L K + + S +P
Sbjct: 2729 PPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSVENRP 2776
>gi|222537747 hypothetical protein LOC342979 [Homo sapiens]
Length = 673
Score = 41.6 bits (96), Expect = 0.002
Identities = 41/179 (22%), Positives = 71/179 (39%), Gaps = 22/179 (12%)
Query: 371 VSSRFSEEGPRSTDDTWP---RGSRSNSSSEAVLGQEELSAQAKVLAPGASH--PGEEEG 425
V + EE P +T + +G +E G+E L + G + G EG
Sbjct: 488 VEKKGGEEEPEATKEPLEAERKGGEETLEAEKRGGEESLETEKTQGTEGDLNLEQGSREG 547
Query: 426 ARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRRSSLGE 485
+ + + P+ A++E EKEG + +E+ G E + + E
Sbjct: 548 SESQAEEMNEAGPPLEANTETRPEKEGPQPQEKP----------VGALEEEGVKPQTAAE 597
Query: 486 KGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHPV-------KPLSAAPVEG 537
GP+ A+P + + + + L + + P+ PS HPV +P +AP EG
Sbjct: 598 GQGPLGDATPLLAETPAPEQPAECQPLLQGEGPSANPSAHPVPTYAPARQPEPSAPTEG 656
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 41.6 bits (96), Expect = 0.002
Identities = 62/246 (25%), Positives = 94/246 (38%), Gaps = 34/246 (13%)
Query: 349 QGPVRHRSSISGSLPSSGSLQAVSSRFSEE---GPRSTDDTWPRGSRSNSSSEAVLGQEE 405
QG + +S S +SG A R EE GP + P S + SE+ + EE
Sbjct: 858 QGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEV-LEE 916
Query: 406 LSAQAKVLAPGASHPGEEEGARLPEGKPVQVAT-----PIVASSEA--VAEKEGARKEER 458
+S + L + + +P T P A EA VA G+ K +
Sbjct: 917 ISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQ 976
Query: 459 KPRMGLFHHHHQGLSRSELGRRSSLG----------EKGGPILGASPHHSSS--GEEKAK 506
K H H+ + +GRR G EK +LG S G EK++
Sbjct: 977 KEHQKE-HRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSR 1035
Query: 507 SSWFGLREAKDPT-------QKPSPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKL 559
G +AK PT PS P P +A V G R+++ ++ + L KL
Sbjct: 1036 PDLGGASKAKPPTAPAPPSAPAPSAQPTPP--SASVPGKKAREEAPGPPGVSRADML-KL 1092
Query: 560 KTVTSG 565
++++ G
Sbjct: 1093 RSLSEG 1098
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 40.8 bits (94), Expect = 0.004
Identities = 80/344 (23%), Positives = 118/344 (34%), Gaps = 48/344 (13%)
Query: 181 SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPD----LGSLGKMGKAKGFFL 236
S DKP SP ++RDK +A+ P+ E P S G+ G+A G
Sbjct: 333 SPPDKPSSPSPRVRDK--------AAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAG 384
Query: 237 RNKLRKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQS 296
R + R+ +S +S + A + L+R+ S S S G
Sbjct: 385 RRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPE 444
Query: 297 PKLFTHKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRS 356
P +R + + + PPR A S+ G+H P+G RS
Sbjct: 445 P---GSERGHGGHGKRAKERPPR----------ARPASTSPSPGAHGRRGGPEGKSSSRS 491
Query: 357 --SISGSLPSSGSLQAVSSRFSEEGPRS-----------TDDTWPRGSRSNSSSEAVLGQ 403
S SS S SR +E+ P S + D G +S +EA +
Sbjct: 492 PGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRAR 551
Query: 404 EELSAQAKVLAPGASHPGEEEGARLPEG--KPVQVATPIVASSEAVAEKE-GARKEERKP 460
+ + + P E R+ +P+ P +SS + + R R P
Sbjct: 552 RRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSP 611
Query: 461 RMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASP-HHSSSGEE 503
G H H S G RS P SP +HS S E
Sbjct: 612 SPG---HSHGSYSSRSHGTRS---RTRSPSRTPSPSYHSRSSSE 649
>gi|28460688 taxilin [Homo sapiens]
Length = 546
Score = 40.0 bits (92), Expect = 0.007
Identities = 57/235 (24%), Positives = 98/235 (41%), Gaps = 23/235 (9%)
Query: 403 QEELSAQAKVLAPGASHPGEEEGARLPEG---KPVQVATPIVA----SSEAVAEKEGARK 455
Q++ + AK P +S PG+ E PEG +P Q A + A SS+A + EGA
Sbjct: 4 QDKKNGAAKQSNPKSS-PGQPEAG--PEGAQERPSQAAPAVEAEGPGSSQAPRKPEGA-- 58
Query: 456 EERKPRMGLFHHHHQGLSRSELGRRSSL---GEKGGPILGASPHHSSSGEEKAKSSWFGL 512
+ R + G + LSR S+ +GGP + + E+ KS +
Sbjct: 59 QARTAQSGALRDVSEELSRQLEDILSTYCVDNNQGGPGEDGAQGEPAEPEDAEKSRTYVA 118
Query: 513 REAKDPTQKPSPHPVKPLSAAPVEGSPDRKQSRSSLSIA-LSSGLEKLKTVTSGSIQPVT 571
R + P P PV P +G P+ ++ R S + + K G + +T
Sbjct: 119 RNGE-----PEPTPVVNGEKEPSKGDPNTEEIRQSDEVGDRDHRRPQEKKKAKGLGKEIT 173
Query: 572 QAPQAGQMVDTKRLKDSAVLDQSAKYY--HLTHDELISLLLQRERELSQRDEHVQ 624
Q + T K +A+ + A+ H + + LL +++ +L Q +H++
Sbjct: 174 LLMQTLNTLSTPEEKLAALCKKYAELLEEHRNSQKQMKLLQKKQSQLVQEKDHLR 228
>gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo
sapiens]
Length = 778
Score = 40.0 bits (92), Expect = 0.007
Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 8/77 (10%)
Query: 21 VQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVEKTHGCPEWREECSFEL--- 77
V +T++ R L+ S SD Y ++G +KY + ++ KT P+WRE+ F L
Sbjct: 251 VSITLIEGRDLKAMDSNG--LSDPYVKFRLGHQKYKSKIMPKTLN-PQWREQFDFHLYEE 307
Query: 78 PPGALDGLLRAQEADAG 94
G +D + A + DAG
Sbjct: 308 RGGVID--ITAWDKDAG 322
>gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Homo
sapiens]
Length = 999
Score = 40.0 bits (92), Expect = 0.007
Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 8/77 (10%)
Query: 21 VQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVEKTHGCPEWREECSFEL--- 77
V +T++ R L+ S SD Y ++G +KY + ++ KT P+WRE+ F L
Sbjct: 472 VSITLIEGRDLKAMDSNG--LSDPYVKFRLGHQKYKSKIMPKTLN-PQWREQFDFHLYEE 528
Query: 78 PPGALDGLLRAQEADAG 94
G +D + A + DAG
Sbjct: 529 RGGVID--ITAWDKDAG 543
>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
Length = 1499
Score = 39.3 bits (90), Expect = 0.012
Identities = 76/301 (25%), Positives = 117/301 (38%), Gaps = 56/301 (18%)
Query: 379 GPRSTDDTWPRGSRSN--------SSSEAVLGQEELSAQAKVLAPGASH----------P 420
GP S +D P G+ N ++ + GQ ++ PGA H P
Sbjct: 163 GPDSEEDDKPIGATHNCNVADPAMAAPQLGPGQTTQLPLSESSVPGAPHGPPPGLRPDAP 222
Query: 421 GEEEGARLPEGKP----VQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSE 476
G G GKP V V T +A++ A A +G + +H Q + R++
Sbjct: 223 GGGGGGGGVPGKPPSQFVYVFTTHLANTAAEAVLQGRADS-------ILAYHQQNVPRAK 275
Query: 477 LGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHPVKPLSAAPV- 535
L + + P+ ++P S+G +++ P P P P P SA P
Sbjct: 276 LDQAPKVPPTPEPLPLSTP---SAGTPQSQ-----------PPPLPPPPPPAPGSAPPAL 321
Query: 536 --EGSP-DRKQSRSSLSIALSS---GLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSA 589
EG P D Q + S+ +S G T + P G D A
Sbjct: 322 PPEGPPEDSSQDLAPNSVGAASTGGGTGGTHPNTPTATTANNPLPPGG---DPSSAPGPA 378
Query: 590 VLDQSAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQIPP 649
+L ++A + + S L +E +L R+ +Q L I+RLL+R ET P L+ PP
Sbjct: 379 LLGEAAAPGNGQRSLVGSEGLSKE-QLEHRERSLQTLRD-IERLLLRSGETEP-FLKGPP 435
Query: 650 G 650
G
Sbjct: 436 G 436
>gi|42518068 trans-golgi network protein 2 [Homo sapiens]
Length = 437
Score = 38.9 bits (89), Expect = 0.015
Identities = 75/343 (21%), Positives = 125/343 (36%), Gaps = 73/343 (21%)
Query: 238 NKLRKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSP 297
NK + TQ ++S S + + GS + G A+ S S+S Q+P
Sbjct: 82 NKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKS--------HPELQTP 133
Query: 298 KLFTHKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSS 357
K T K EA +P R+ + + D+ S+S GS + V ++S
Sbjct: 134 KDSTGKS--GAEAQTPEDSPNRSGAEAKTQKDSPSKS-----GSEAQTTKD---VPNKSG 183
Query: 358 ISGSLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVL---GQEELSAQAKVLA 414
G P GS ++ +D P+ + S +E G + A+ +
Sbjct: 184 ADGQTPKDGSSKS-----------GAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPI 232
Query: 415 PGASHPGEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSR 474
G S G EE S V ++ +RK+ KP ++ L +
Sbjct: 233 DGPSKSGAEEQTSKD-------------SPNKVVPEQPSRKDHSKPISN--PSDNKELPK 277
Query: 475 SELGRRSSLGEKGGPILGASPH--HSSSGEE---------KAKSSWFGLREAKDPTQKPS 523
++ + + G+ SPH + SGEE + KSS +PT+
Sbjct: 278 ADTNQLADKGK-------LSPHAFKTESGEETDLISPPQEEVKSS--------EPTEDVE 322
Query: 524 PHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGS 566
P + P EGSP +++ A S E + ++GS
Sbjct: 323 PKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGS 365
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 38.5 bits (88), Expect = 0.020
Identities = 55/191 (28%), Positives = 71/191 (37%), Gaps = 26/191 (13%)
Query: 325 QGHLDAASRSSLCVNGSH-IYNEEPQGPVRHRSSISGSLPSSGSLQAVSSRFSEEGPRST 383
QG DA+ S + S NEE G S SGS S QA SSR S+ G
Sbjct: 3794 QGRSDASHGQSGSRSASRETRNEEQSGD---GSRHSGSRHHEASTQADSSRHSQSG--QG 3848
Query: 384 DDTWPRGSR-------SNSSSEAVL-GQEELSAQAKVLAPGASHPGEEEGARLPEGKPVQ 435
+ R SR +S SEA E S A G+S +G+R P
Sbjct: 3849 ESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRD 3908
Query: 436 VATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASP 495
A+ + S V KE H H LS+ S + +G P +S
Sbjct: 3909 TASHV--QSSPVQSDSSTAKE---------HGHFSSLSQDS-AYHSGIQSRGSPHSSSSY 3956
Query: 496 HHSSSGEEKAK 506
H+ S G E+ K
Sbjct: 3957 HYQSEGTERQK 3967
>gi|214010165 rab11-family interacting protein 3 isoform 2 [Homo
sapiens]
Length = 460
Score = 37.4 bits (85), Expect = 0.044
Identities = 19/54 (35%), Positives = 37/54 (68%), Gaps = 7/54 (12%)
Query: 594 SAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQI 647
+A+ ++ DEL+ + Q++ E++ R L+ YIDR++V IMET+P++L++
Sbjct: 413 AAEISSVSRDELMEAI-QKQEEINFR------LQDYIDRIIVAIMETNPSILEV 459
>gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo
sapiens]
Length = 756
Score = 37.4 bits (85), Expect = 0.044
Identities = 19/54 (35%), Positives = 37/54 (68%), Gaps = 7/54 (12%)
Query: 594 SAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQI 647
+A+ ++ DEL+ + Q++ E++ R L+ YIDR++V IMET+P++L++
Sbjct: 709 AAEISSVSRDELMEAI-QKQEEINFR------LQDYIDRIIVAIMETNPSILEV 755
>gi|56699475 zinc finger protein 202 [Homo sapiens]
Length = 648
Score = 37.4 bits (85), Expect = 0.044
Identities = 42/133 (31%), Positives = 55/133 (41%), Gaps = 15/133 (11%)
Query: 442 ASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSE----LG-RRSSLGEKGGPILGASPH 496
+ EAV EG +K+ R+PR + H H SE LG S E P+ ++P
Sbjct: 113 SGEEAVTLVEGLQKQPRRPRRWVTVHVHGQEVLSEETVHLGVEPESPNELQDPVQSSTPE 172
Query: 497 HSSSGEEKAKSSWFGLREAKDPTQKPSPHPVKPLSAAPVEGSPDRKQSRSS-------LS 549
S EE +S G + P Q+ ++ S PV PD RSS L
Sbjct: 173 QSP--EETTQSPDLGAPAEQRPHQEEELQTLQE-SEVPVPEDPDLPAERSSGDSEMVALL 229
Query: 550 IALSSGLEKLKTV 562
ALS GL K V
Sbjct: 230 TALSQGLVTFKDV 242
>gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo
sapiens]
Length = 678
Score = 37.0 bits (84), Expect = 0.057
Identities = 31/124 (25%), Positives = 46/124 (37%), Gaps = 6/124 (4%)
Query: 429 PEGKPVQVATPIVASSEAVAEKEGARKEE--RKPRMGLFHHHHQGLSRSELGRRSSLGEK 486
P P + P GAR+ + +K F H +GL R R S G
Sbjct: 106 PRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHS 165
Query: 487 GGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHPVKPL---SAAPVEGSPDRKQ 543
P A P + +G W E+ DP+ P P P P ++ P +P ++Q
Sbjct: 166 A-PEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQ 224
Query: 544 SRSS 547
S+
Sbjct: 225 CVSA 228
>gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo
sapiens]
Length = 650
Score = 37.0 bits (84), Expect = 0.057
Identities = 31/124 (25%), Positives = 46/124 (37%), Gaps = 6/124 (4%)
Query: 429 PEGKPVQVATPIVASSEAVAEKEGARKEE--RKPRMGLFHHHHQGLSRSELGRRSSLGEK 486
P P + P GAR+ + +K F H +GL R R S G
Sbjct: 106 PRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHS 165
Query: 487 GGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHPVKPL---SAAPVEGSPDRKQ 543
P A P + +G W E+ DP+ P P P P ++ P +P ++Q
Sbjct: 166 A-PEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQ 224
Query: 544 SRSS 547
S+
Sbjct: 225 CVSA 228
>gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B
subunit [Homo sapiens]
Length = 2339
Score = 36.6 bits (83), Expect = 0.075
Identities = 79/330 (23%), Positives = 125/330 (37%), Gaps = 56/330 (16%)
Query: 256 STLSSASGSLAY-QGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLFTHKRTYSDEANQMR 314
S +S+A+ S+A Q A+ + R+S L + R S ++ L++ D ++R
Sbjct: 745 SPMSAANISIAARQQNSAKARSVWEQRASQLRLQNLRASCEA--LYSEM----DPEERLR 798
Query: 315 VAPPRALL-DLQGHLDAASRSSLCVNGSH---------IYNEEPQG--PVR--HRSSISG 360
A R L D++ HLD L +G+ E P+G P R HR
Sbjct: 799 FATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAAEAPEGVDPPRRHHRHRDKD 858
Query: 361 SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP 420
P++G + +E G + PR RS+S +E + + + P
Sbjct: 859 KTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHS--------KEAAGPPEARSERGRGP 910
Query: 421 GEEEGAR-LPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGR 479
G E G R G P +E A +E R+ R H HQ S+ G
Sbjct: 911 GPEGGRRHHRRGSP----------------EEAAEREPRRHRA----HRHQDPSKECAGA 950
Query: 480 RSS--LGEKGGPILGASPHHSSSGEEKAK--SSWFGLREAKDPTQKPSPHPVKPLSAAPV 535
+ +GGP A P + SGEE A+ + + A + +K + A +
Sbjct: 951 KGERRARHRGGP--RAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEI 1008
Query: 536 EGSPDRKQSRSSLSIALSSGLEKLKTVTSG 565
+ K+ R+ LE TVT G
Sbjct: 1009 VEADKEKELRNHQPREPHCDLETSGTVTVG 1038
>gi|122937247 unc-13 homolog A [Homo sapiens]
Length = 1791
Score = 36.6 bits (83), Expect = 0.075
Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
Query: 12 GPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVEKTHGCPEWRE 71
G S+W + +TV+ A+GL+ K +SD Y +QVG+ K T + P W E
Sbjct: 758 GTSKW-SAKISITVVCAQGLQAKDKTG--SSDPYVTVQVGKTKKRTKTIYGNLN-PVWEE 813
Query: 72 ECSFE 76
FE
Sbjct: 814 NFHFE 818
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 36.6 bits (83), Expect = 0.075
Identities = 61/235 (25%), Positives = 84/235 (35%), Gaps = 17/235 (7%)
Query: 256 STLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLFTHKRTYSD-EANQMR 314
ST + +LA P E RS S SS S+ S+ S + + SD E + +
Sbjct: 2512 STGAQQPSALAALQPAKE--RRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLP 2569
Query: 315 VAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISGSLPSSGSLQAVSSR 374
V P AL + A + EP R R S S S SS S + SS
Sbjct: 2570 VQPEVALKRVPSPTPAPKEAV-----REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSS 2624
Query: 375 FSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHPGEEEGARLPEGKPV 434
S S+ + S S+SSS + A K +P PGE +R P KP+
Sbjct: 2625 SSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERR-SRSPR-KPI 2682
Query: 435 QVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRRSSLGEKGGP 489
+ S + E+ R+P Q S RR G+ P
Sbjct: 2683 DSLRDSRSLSYSPVER-------RRPSPQPSPRDQQSSSSERGSRRGQRGDSRSP 2730
Score = 36.2 bits (82), Expect = 0.098
Identities = 45/162 (27%), Positives = 64/162 (39%), Gaps = 18/162 (11%)
Query: 389 RGSRSNSSSEAVLGQEELSAQAKVLAPGASHPGEEEGARLPEGKPV---QVATPIVASSE 445
R S S+SSS + S+ + + G+S + EG+ LP V +V +P A E
Sbjct: 2530 RRSSSSSSSSSSSSSSSSSSSSSSSSSGSSS-SDSEGSSLPVQPEVALKRVPSPTPAPKE 2588
Query: 446 AVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKA 505
AV E R E P S S SS +S SSS +
Sbjct: 2589 AVRE---GRPPEPTPAKRKRRSSSSSSSSSSSSSSSS---------SSSSSSSSSSSSSS 2636
Query: 506 KSSWFGLREAKDPT-QKPSPHPVKPLSAAPVEGSPDRKQSRS 546
SS + P+ KP P + P A+P + P ++SRS
Sbjct: 2637 SSSSSSSSSSSSPSPAKPGPQAL-PKPASPKKPPPGERRSRS 2677
Score = 30.4 bits (67), Expect = 5.4
Identities = 58/242 (23%), Positives = 75/242 (30%), Gaps = 32/242 (13%)
Query: 356 SSISGSLPSSGSL--------QAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVL----GQ 403
SS G PS L V S FS++ T P + SS AV
Sbjct: 2428 SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSA 2487
Query: 404 EELSAQAKVLAPGASHPGEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMG 463
+ + V APG H E P Q + + A A KE R
Sbjct: 2488 GDHNGMLSVPAPGVPHSDVGEP---PASTGAQQPSALAALQPA--------KERRSSSSS 2536
Query: 464 LFHHHHQGLSRSELGRRSSLGEKGGPILGAS-PHHSSSGEEKAKSSWFGLREAKDPTQKP 522
S S SS G G+S P ++ S +EA + P
Sbjct: 2537 SSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPP 2596
Query: 523 SPHPVK--------PLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAP 574
P P K S++ S S SS S + SS + +S S P P
Sbjct: 2597 EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP 2656
Query: 575 QA 576
QA
Sbjct: 2657 QA 2658
>gi|122937514 unc-13 homolog C [Homo sapiens]
Length = 2214
Score = 36.2 bits (82), Expect = 0.098
Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 4/65 (6%)
Query: 12 GPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVEKTHGCPEWRE 71
G S+W + +TV+ A+GL+ K +SD Y +QVG+ K T + P W E
Sbjct: 1214 GTSKW-SAKITITVVSAQGLQAKDKTG--SSDPYVTVQVGKNKRRTKTIFGNLN-PVWDE 1269
Query: 72 ECSFE 76
+ FE
Sbjct: 1270 KFYFE 1274
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 36.2 bits (82), Expect = 0.098
Identities = 26/71 (36%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
Query: 237 RNKLRKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQS 296
RNK KS S++S S S+ SS+SGS + G + S S SS S RDS+ S
Sbjct: 567 RNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSS--RSSSSSSSSTSGSSSRDSSSS 624
Query: 297 PKLFTHKRTYS 307
+ R+ S
Sbjct: 625 TSSSSESRSRS 635
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 36.2 bits (82), Expect = 0.098
Identities = 24/83 (28%), Positives = 33/83 (39%)
Query: 467 HHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHP 526
H H G R+E+ + S GG AS SSS K + S K + PS +
Sbjct: 235 HSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYK 294
Query: 527 VKPLSAAPVEGSPDRKQSRSSLS 549
P + + P + R SLS
Sbjct: 295 EPPKAYREDKTEPKAYRRRRSLS 317
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 36.2 bits (82), Expect = 0.098
Identities = 24/83 (28%), Positives = 33/83 (39%)
Query: 467 HHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHP 526
H H G R+E+ + S GG AS SSS K + S K + PS +
Sbjct: 235 HSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYK 294
Query: 527 VKPLSAAPVEGSPDRKQSRSSLS 549
P + + P + R SLS
Sbjct: 295 EPPKAYREDKTEPKAYRRRRSLS 317
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 35.8 bits (81), Expect = 0.13
Identities = 71/312 (22%), Positives = 106/312 (33%), Gaps = 39/312 (12%)
Query: 121 DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL 180
D+ G + + +E G+AQ + S+ K KE+ E +L
Sbjct: 145 DRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKER--------------EL 190
Query: 181 SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKG--FFLRN 238
K RS + R+ K K D + P D G + G + L
Sbjct: 191 KSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSP 250
Query: 239 KLRKSSLTQSNTSLGSDSTLSSASGSLAYQGPGA-ELLTRSPS--------------RSS 283
+S + ST S S Y+ P A + TRSPS R S
Sbjct: 251 SRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRS 310
Query: 284 WLSTEGGRDSAQSPKLFTHKRTYSDEANQMRVA----PPRALLDLQGHLDAASRSSLCVN 339
G S +SP + +R+ S ++ ++ P R + + A SR S
Sbjct: 311 SSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHS---- 366
Query: 340 GSHIYNEEPQGPVRHRSSISGSLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEA 399
SH + RH S LP + SL A SR +E + G S S
Sbjct: 367 SSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVF 426
Query: 400 VLGQEELSAQAK 411
+ +E S +AK
Sbjct: 427 LPRKENSSVEAK 438
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 35.8 bits (81), Expect = 0.13
Identities = 71/312 (22%), Positives = 106/312 (33%), Gaps = 39/312 (12%)
Query: 121 DKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDL 180
D+ G + + +E G+AQ + S+ K KE+ E +L
Sbjct: 145 DRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKER--------------EL 190
Query: 181 SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKG--FFLRN 238
K RS + R+ K K D + P D G + G + L
Sbjct: 191 KSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSP 250
Query: 239 KLRKSSLTQSNTSLGSDSTLSSASGSLAYQGPGA-ELLTRSPS--------------RSS 283
+S + ST S S Y+ P A + TRSPS R S
Sbjct: 251 SRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRS 310
Query: 284 WLSTEGGRDSAQSPKLFTHKRTYSDEANQMRVA----PPRALLDLQGHLDAASRSSLCVN 339
G S +SP + +R+ S ++ ++ P R + + A SR S
Sbjct: 311 SSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHS---- 366
Query: 340 GSHIYNEEPQGPVRHRSSISGSLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEA 399
SH + RH S LP + SL A SR +E + G S S
Sbjct: 367 SSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVF 426
Query: 400 VLGQEELSAQAK 411
+ +E S +AK
Sbjct: 427 LPRKENSSVEAK 438
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.126 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,174,309
Number of Sequences: 37866
Number of extensions: 1319152
Number of successful extensions: 5658
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 212
Number of HSP's that attempted gapping in prelim test: 5382
Number of HSP's gapped (non-prelim): 495
length of query: 653
length of database: 18,247,518
effective HSP length: 109
effective length of query: 544
effective length of database: 14,120,124
effective search space: 7681347456
effective search space used: 7681347456
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.