Guide to the Human Genome
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Name: PITX2 Sequence: fasta or formatted (271aa) NCBI GI: 24234711
Description:

paired-like homeodomain transcription factor 2 isoform a

Referenced in:

Homeobox and Related Proteins
Left-Right Axis
Pituitary

Other entries for this name:
alt prot [324aa] paired-like homeodomain transcription factor 2 isoform c
alt prot [317aa] paired-like homeodomain transcription factor 2 isoform b
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.4         20           2
 C cysteine            2.2          6           1
 D aspartate           3.0          8           2
 E glutamate           4.1         11           2
 F phenylalanine       3.7         10           2
 G glycine             3.7         10           1
 H histidine           0.7          2           1
 I isoleucine          0.7          2           1
 K lysine              5.5         15           3
 L leucine             7.0         19           1
 M methionine          3.3          9           1
 N asparagine          8.5         23           2
 P proline             7.7         21           2
 Q glutamine           6.3         17           2
 R arginine            6.6         18           2
 S serine             14.0         38           3
 T threonine           4.8         13           1
 V valine              5.5         15           1
 W tryptophan          1.5          4           1
 Y tyrosine            3.7         10           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   paired-like homeodomain transcription factor 2 isofo... 
PITX2                 0.958   paired-like homeodomain transcription factor 2 isofo...
PITX2                 0.943   paired-like homeodomain transcription factor 2 isofo...
PITX1                 0.633   paired-like homeodomain transcription factor 1 [Hom...
PITX3                 0.514   paired-like homeodomain 3 
ALX1                  0.180   cartilage paired-class homeoprotein 1 
ALX4                  0.164   aristaless-like homeobox 4 
ARX                   0.155   aristaless related homeobox 
DRGX                  0.151   dorsal root ganglia homeobox 
PAX7                  0.149   paired box 7 isoform 3 
PAX7                  0.147   paired box 7 isoform 1 
PAX7                  0.147   paired box 7 isoform 2 
ALX3                  0.142   aristaless-like homeobox 3 
RAX                   0.142   retina and anterior neural fold homeobox 
PAX3                  0.129   paired box 3 isoform PAX3i 
PAX3                  0.129   paired box 3 isoform PAX3e 
PAX3                  0.129   paired box 3 isoform PAX3d 
PAX3                  0.129   paired box 3 isoform PAX3 
DMBX1                 0.129   diencephalon/mesencephalon homeobox 1 isoform b [Hom...
DMBX1                 0.129   diencephalon/mesencephalon homeobox 1 isoform a [Hom...
PAX3                  0.127   paired box 3 isoform PAX3g 
PAX3                  0.127   paired box 3 isoform PAX3h 
OTP                   0.125   PREDICTED: orthopedia homeobox 
OTP                   0.125   orthopedia homeobox 
PRRX1                 0.123   paired mesoderm homeobox 1 isoform pmx-1a 
PRRX1                 0.123   paired mesoderm homeobox 1 isoform pmx-1b 
PHOX2B                0.117   paired-like homeobox 2b 
VSX1                  0.117   visual system homeobox 1 isoform a 
OTX1                  0.117   orthodenticle homeobox 1 
PHOX2A                0.117   paired-like homeobox 2a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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