Search of human proteins with 239756966

Search of human proteins with 239756966

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239756966 PREDICTED: similar to arg tyrosine kinase [Homo
sapiens]
         (243 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239756966 PREDICTED: similar to arg tyrosine kinase [Homo sap...   502   e-142
gi|187937179 apoptosis-associated tyrosine kinase [Homo sapiens]      212   2e-55
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                   136   2e-32
gi|38016937 lemur tyrosine kinase 2 [Homo sapiens]                    121   5e-28
gi|15826840 PTK7 protein tyrosine kinase 7 isoform a precursor [...    77   1e-14
gi|22902130 PTK7 protein tyrosine kinase 7 isoform d precursor [...    77   1e-14
gi|22902128 PTK7 protein tyrosine kinase 7 isoform c precursor [...    77   1e-14
gi|22902126 PTK7 protein tyrosine kinase 7 isoform b precursor [...    77   1e-14
gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]              74   9e-14
gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]                74   9e-14
gi|209862778 arg tyrosine kinase isoform e [Homo sapiens]              74   9e-14
gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]              74   9e-14
gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]              74   9e-14
gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a...    72   3e-13
gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b...    72   3e-13
gi|119395738 insulin receptor isoform Short precursor [Homo sapi...    72   6e-13
gi|119395736 insulin receptor isoform Long precursor [Homo sapiens]    72   6e-13
gi|31657140 insulin receptor-related receptor precursor [Homo sa...    70   1e-12
gi|4557665 insulin-like growth factor 1 receptor precursor [Homo...    70   2e-12
gi|62420886 discoidin domain receptor family, member 2 precursor...    68   8e-12
gi|62420884 discoidin domain receptor family, member 2 precursor...    68   8e-12
gi|29029632 anaplastic lymphoma kinase [Homo sapiens]                  65   5e-11
gi|59889558 neurotrophic tyrosine kinase, receptor, type 1 isofo...    64   2e-10
gi|4585712 neurotrophic tyrosine kinase, receptor, type 1 isofor...    64   2e-10
gi|56118210 neurotrophic tyrosine kinase, receptor, type 1 isofo...    64   2e-10
gi|208879423 leukocyte receptor tyrosine kinase isoform 3 precur...    64   2e-10
gi|42544153 leukocyte receptor tyrosine kinase isoform 1 precurs...    64   2e-10
gi|46249416 leukocyte receptor tyrosine kinase isoform 2 precurs...    64   2e-10
gi|54607018 RYK receptor-like tyrosine kinase isoform 2 [Homo sa...    63   2e-10
gi|54607020 RYK receptor-like tyrosine kinase isoform 1 [Homo sa...    63   2e-10

>gi|239756966 PREDICTED: similar to arg tyrosine kinase [Homo
           sapiens]
          Length = 243

 Score =  502 bits (1292), Expect = e-142
 Identities = 243/243 (100%), Positives = 243/243 (100%)

Query: 1   MQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDP 60
           MQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDP
Sbjct: 1   MQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDP 60

Query: 61  RTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKIDPAAPAPAAPTPTPAPFS 120
           RTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKIDPAAPAPAAPTPTPAPFS
Sbjct: 61  RTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKIDPAAPAPAAPTPTPAPFS 120

Query: 121 RFTVSPAPTSRFSITHVSDSDAESKRDLRQALSPEPSQPEVPADPGPTVPRPHGAQDLKL 180
           RFTVSPAPTSRFSITHVSDSDAESKRDLRQALSPEPSQPEVPADPGPTVPRPHGAQDLKL
Sbjct: 121 RFTVSPAPTSRFSITHVSDSDAESKRDLRQALSPEPSQPEVPADPGPTVPRPHGAQDLKL 180

Query: 181 VPGVRVKRLETWAAPAPQGWRHRSPCQAAARMVTEKVGTTSWWLLAADSGASAPRGVLEK 240
           VPGVRVKRLETWAAPAPQGWRHRSPCQAAARMVTEKVGTTSWWLLAADSGASAPRGVLEK
Sbjct: 181 VPGVRVKRLETWAAPAPQGWRHRSPCQAAARMVTEKVGTTSWWLLAADSGASAPRGVLEK 240

Query: 241 PVG 243
           PVG
Sbjct: 241 PVG 243


>gi|187937179 apoptosis-associated tyrosine kinase [Homo sapiens]
          Length = 1374

 Score =  212 bits (540), Expect = 2e-55
 Identities = 102/102 (100%), Positives = 102/102 (100%)

Query: 1   MQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDP 60
           MQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDP
Sbjct: 168 MQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDP 227

Query: 61  RTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
           RTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI
Sbjct: 228 RTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 269



 Score = 94.4 bits (233), Expect = 8e-20
 Identities = 45/51 (88%), Positives = 47/51 (92%)

Query: 96   ADLTVKIDPAAPAPAAPTPTPAPFSRFTVSPAPTSRFSITHVSDSDAESKR 146
            A   + +DPAAPAPAAPTPTPAPFSRFTVSPAPTSRFSITHVSDSDAESKR
Sbjct: 1311 AAFAMALDPAAPAPAAPTPTPAPFSRFTVSPAPTSRFSITHVSDSDAESKR 1361


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score =  136 bits (342), Expect = 2e-32
 Identities = 65/106 (61%), Positives = 81/106 (76%), Gaps = 5/106 (4%)

Query: 2   QFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAP--- 58
           +F+ E QPYR+L+H N+LQCL  C E  P+LL+MEFC LGDLK YLR+ R  E ++P   
Sbjct: 206 KFISEAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQLGDLKRYLRAQRPPEGLSPELP 265

Query: 59  --DPRTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
             D RTLQRM  E+A G+ HLH +N+VHSDLALRNCLLT+DLTV+I
Sbjct: 266 PRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRI 311


>gi|38016937 lemur tyrosine kinase 2 [Homo sapiens]
          Length = 1503

 Score =  121 bits (304), Expect = 5e-28
 Identities = 61/102 (59%), Positives = 74/102 (72%), Gaps = 4/102 (3%)

Query: 3   FLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDPRT 62
           FL+  +PY  L+H N+LQC+ QC E  PYLLV EFC LGDLK YLRS    E M  D +T
Sbjct: 182 FLKNGEPYYILQHPNILQCVGQCVEAIPYLLVFEFCDLGDLKAYLRS--EQEHMRGDSQT 239

Query: 63  --LQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
             LQRMACEVA G+  +H+ +F+HSDLALRNC LT+DL VK+
Sbjct: 240 MLLQRMACEVAAGLAAMHKLHFLHSDLALRNCFLTSDLNVKV 281



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 21/41 (51%), Positives = 28/41 (68%), Gaps = 4/41 (9%)

Query: 107  PAPAAPT----PTPAPFSRFTVSPAPTSRFSITHVSDSDAE 143
            P PA  T    P  AP+SRF++SPA  + FS+TH++DSD E
Sbjct: 1452 PPPARSTEQSWPHSAPYSRFSISPANIASFSLTHLTDSDIE 1492


>gi|15826840 PTK7 protein tyrosine kinase 7 isoform a precursor
           [Homo sapiens]
          Length = 1070

 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 43/106 (40%), Positives = 64/106 (60%), Gaps = 4/106 (3%)

Query: 1   MQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLR-SCRVAESMAPD 59
           + F  E++ +  L H+N+++ L  C E  P+ +V+E+  LGDLK +LR S    E +   
Sbjct: 841 LDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQ 900

Query: 60  P-RTLQRMA--CEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
           P  T Q++A   +VA G+ HL  N FVH DLA RNCL++A   VK+
Sbjct: 901 PLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKV 946


>gi|22902130 PTK7 protein tyrosine kinase 7 isoform d precursor
           [Homo sapiens]
          Length = 1014

 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 43/106 (40%), Positives = 64/106 (60%), Gaps = 4/106 (3%)

Query: 1   MQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLR-SCRVAESMAPD 59
           + F  E++ +  L H+N+++ L  C E  P+ +V+E+  LGDLK +LR S    E +   
Sbjct: 785 LDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQ 844

Query: 60  P-RTLQRMA--CEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
           P  T Q++A   +VA G+ HL  N FVH DLA RNCL++A   VK+
Sbjct: 845 PLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKV 890


>gi|22902128 PTK7 protein tyrosine kinase 7 isoform c precursor
           [Homo sapiens]
          Length = 940

 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 43/106 (40%), Positives = 64/106 (60%), Gaps = 4/106 (3%)

Query: 1   MQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLR-SCRVAESMAPD 59
           + F  E++ +  L H+N+++ L  C E  P+ +V+E+  LGDLK +LR S    E +   
Sbjct: 711 LDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQ 770

Query: 60  P-RTLQRMA--CEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
           P  T Q++A   +VA G+ HL  N FVH DLA RNCL++A   VK+
Sbjct: 771 PLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKV 816


>gi|22902126 PTK7 protein tyrosine kinase 7 isoform b precursor
           [Homo sapiens]
          Length = 1030

 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 43/106 (40%), Positives = 64/106 (60%), Gaps = 4/106 (3%)

Query: 1   MQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLR-SCRVAESMAPD 59
           + F  E++ +  L H+N+++ L  C E  P+ +V+E+  LGDLK +LR S    E +   
Sbjct: 801 LDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQ 860

Query: 60  P-RTLQRMA--CEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
           P  T Q++A   +VA G+ HL  N FVH DLA RNCL++A   VK+
Sbjct: 861 PLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKV 906


>gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]
          Length = 1167

 Score = 74.3 bits (181), Expect = 9e-14
 Identities = 38/101 (37%), Positives = 57/101 (56%), Gaps = 3/101 (2%)

Query: 2   QFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDPR 61
           +FL+E    + +KH NL+Q L  C    P+ +V E+ P G+L  YLR C   E  A    
Sbjct: 313 EFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAV--- 369

Query: 62  TLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
            L  MA +++  + +L + NF+H DLA RNCL+  +  VK+
Sbjct: 370 VLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKV 410


>gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]
          Length = 1182

 Score = 74.3 bits (181), Expect = 9e-14
 Identities = 38/101 (37%), Positives = 57/101 (56%), Gaps = 3/101 (2%)

Query: 2   QFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDPR 61
           +FL+E    + +KH NL+Q L  C    P+ +V E+ P G+L  YLR C   E  A    
Sbjct: 328 EFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAV--- 384

Query: 62  TLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
            L  MA +++  + +L + NF+H DLA RNCL+  +  VK+
Sbjct: 385 VLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKV 425


>gi|209862778 arg tyrosine kinase isoform e [Homo sapiens]
          Length = 542

 Score = 74.3 bits (181), Expect = 9e-14
 Identities = 38/101 (37%), Positives = 57/101 (56%), Gaps = 3/101 (2%)

Query: 2   QFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDPR 61
           +FL+E    + +KH NL+Q L  C    P+ +V E+ P G+L  YLR C   E  A    
Sbjct: 307 EFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAV--- 363

Query: 62  TLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
            L  MA +++  + +L + NF+H DLA RNCL+  +  VK+
Sbjct: 364 VLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKV 404


>gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]
          Length = 1064

 Score = 74.3 bits (181), Expect = 9e-14
 Identities = 38/101 (37%), Positives = 57/101 (56%), Gaps = 3/101 (2%)

Query: 2   QFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDPR 61
           +FL+E    + +KH NL+Q L  C    P+ +V E+ P G+L  YLR C   E  A    
Sbjct: 313 EFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAV--- 369

Query: 62  TLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
            L  MA +++  + +L + NF+H DLA RNCL+  +  VK+
Sbjct: 370 VLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKV 410


>gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]
          Length = 1146

 Score = 74.3 bits (181), Expect = 9e-14
 Identities = 38/101 (37%), Positives = 57/101 (56%), Gaps = 3/101 (2%)

Query: 2   QFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDPR 61
           +FL+E    + +KH NL+Q L  C    P+ +V E+ P G+L  YLR C   E  A    
Sbjct: 292 EFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAV--- 348

Query: 62  TLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
            L  MA +++  + +L + NF+H DLA RNCL+  +  VK+
Sbjct: 349 VLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKV 389


>gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a
           [Homo sapiens]
          Length = 1130

 Score = 72.4 bits (176), Expect = 3e-13
 Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 3/101 (2%)

Query: 2   QFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDPR 61
           +FL+E    + +KH NL+Q L  C    P+ ++ EF   G+L  YLR C   E  A    
Sbjct: 282 EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAV--- 338

Query: 62  TLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
            L  MA +++  + +L + NF+H DLA RNCL+  +  VK+
Sbjct: 339 VLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKV 379


>gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b
           [Homo sapiens]
          Length = 1149

 Score = 72.4 bits (176), Expect = 3e-13
 Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 3/101 (2%)

Query: 2   QFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDPR 61
           +FL+E    + +KH NL+Q L  C    P+ ++ EF   G+L  YLR C   E  A    
Sbjct: 301 EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAV--- 357

Query: 62  TLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
            L  MA +++  + +L + NF+H DLA RNCL+  +  VK+
Sbjct: 358 VLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKV 398


>gi|119395738 insulin receptor isoform Short precursor [Homo sapiens]
          Length = 1370

 Score = 71.6 bits (174), Expect = 6e-13
 Identities = 43/107 (40%), Positives = 60/107 (56%), Gaps = 5/107 (4%)

Query: 1    MQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPD- 59
            ++FL E    +     ++++ L   ++  P L+VME    GDLK YLRS R      P  
Sbjct: 1057 IEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGR 1116

Query: 60   -PRTLQ---RMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
             P TLQ   +MA E+A G+ +L+   FVH DLA RNC++  D TVKI
Sbjct: 1117 PPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKI 1163


>gi|119395736 insulin receptor isoform Long precursor [Homo sapiens]
          Length = 1382

 Score = 71.6 bits (174), Expect = 6e-13
 Identities = 43/107 (40%), Positives = 60/107 (56%), Gaps = 5/107 (4%)

Query: 1    MQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPD- 59
            ++FL E    +     ++++ L   ++  P L+VME    GDLK YLRS R      P  
Sbjct: 1069 IEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGR 1128

Query: 60   -PRTLQ---RMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
             P TLQ   +MA E+A G+ +L+   FVH DLA RNC++  D TVKI
Sbjct: 1129 PPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKI 1175


>gi|31657140 insulin receptor-related receptor precursor [Homo
            sapiens]
          Length = 1297

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 42/107 (39%), Positives = 65/107 (60%), Gaps = 5/107 (4%)

Query: 1    MQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRV-AESMAPD 59
            ++FL+E    +A K  ++++ L   ++  P L++ME    GDLK +LRS R  AE+    
Sbjct: 1025 IEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGL 1084

Query: 60   PRT----LQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
            P+     + +MA E+A G+ +L  N FVH DLA RNC+++ D TVKI
Sbjct: 1085 PQPALGEMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQDFTVKI 1131


>gi|4557665 insulin-like growth factor 1 receptor precursor [Homo
            sapiens]
          Length = 1367

 Score = 69.7 bits (169), Expect = 2e-12
 Identities = 41/107 (38%), Positives = 60/107 (56%), Gaps = 5/107 (4%)

Query: 1    MQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAP-- 58
            ++FL E    +     ++++ L   ++  P L++ME    GDLK YLRS R      P  
Sbjct: 1045 IEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVL 1104

Query: 59   DPRTLQRM---ACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
             P +L +M   A E+A G+ +L+ N FVH DLA RNC++  D TVKI
Sbjct: 1105 APPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKI 1151


>gi|62420886 discoidin domain receptor family, member 2 precursor
           [Homo sapiens]
          Length = 855

 Score = 67.8 bits (164), Expect = 8e-12
 Identities = 39/105 (37%), Positives = 57/105 (54%), Gaps = 5/105 (4%)

Query: 3   FLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDPRT 62
           FL+E++    LK  N++  LA C    P  ++ E+   GDL  +L       S + D RT
Sbjct: 622 FLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRT 681

Query: 63  -----LQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
                L+ MA ++A G+ +L   NFVH DLA RNCL+  + T+KI
Sbjct: 682 VSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKI 726


>gi|62420884 discoidin domain receptor family, member 2 precursor
           [Homo sapiens]
          Length = 855

 Score = 67.8 bits (164), Expect = 8e-12
 Identities = 39/105 (37%), Positives = 57/105 (54%), Gaps = 5/105 (4%)

Query: 3   FLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDPRT 62
           FL+E++    LK  N++  LA C    P  ++ E+   GDL  +L       S + D RT
Sbjct: 622 FLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRT 681

Query: 63  -----LQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
                L+ MA ++A G+ +L   NFVH DLA RNCL+  + T+KI
Sbjct: 682 VSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKI 726


>gi|29029632 anaplastic lymphoma kinase [Homo sapiens]
          Length = 1620

 Score = 65.1 bits (157), Expect = 5e-11
 Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 2/97 (2%)

Query: 1    MQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDP 60
            + FL E        H N+++C+    +  P  +++E    GDLK +LR  R   S     
Sbjct: 1162 LDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSL 1221

Query: 61   RTLQ--RMACEVACGVLHLHRNNFVHSDLALRNCLLT 95
              L    +A ++ACG  +L  N+F+H D+A RNCLLT
Sbjct: 1222 AMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLT 1258


>gi|59889558 neurotrophic tyrosine kinase, receptor, type 1 isoform
           1 [Homo sapiens]
          Length = 790

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 40/110 (36%), Positives = 58/110 (52%), Gaps = 10/110 (9%)

Query: 3   FLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRS-------CRVAES 55
           F  E +    L+H ++++    C E  P L+V E+   GDL  +LRS           E 
Sbjct: 551 FQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGED 610

Query: 56  MAPDPRTLQRM---ACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
           +AP P  L ++   A +VA G+++L   +FVH DLA RNCL+   L VKI
Sbjct: 611 VAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKI 660


>gi|4585712 neurotrophic tyrosine kinase, receptor, type 1 isoform 2
           [Homo sapiens]
          Length = 796

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 40/110 (36%), Positives = 58/110 (52%), Gaps = 10/110 (9%)

Query: 3   FLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRS-------CRVAES 55
           F  E +    L+H ++++    C E  P L+V E+   GDL  +LRS           E 
Sbjct: 557 FQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGED 616

Query: 56  MAPDPRTLQRM---ACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
           +AP P  L ++   A +VA G+++L   +FVH DLA RNCL+   L VKI
Sbjct: 617 VAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKI 666


>gi|56118210 neurotrophic tyrosine kinase, receptor, type 1 isoform
           3 [Homo sapiens]
          Length = 760

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 40/110 (36%), Positives = 58/110 (52%), Gaps = 10/110 (9%)

Query: 3   FLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRS-------CRVAES 55
           F  E +    L+H ++++    C E  P L+V E+   GDL  +LRS           E 
Sbjct: 521 FQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGED 580

Query: 56  MAPDPRTLQRM---ACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
           +AP P  L ++   A +VA G+++L   +FVH DLA RNCL+   L VKI
Sbjct: 581 VAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKI 630


>gi|208879423 leukocyte receptor tyrosine kinase isoform 3 precursor
           [Homo sapiens]
          Length = 734

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 34/98 (34%), Positives = 54/98 (55%), Gaps = 4/98 (4%)

Query: 1   MQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDP 60
           + FL E       +H N+++C+      TP L+++E    GD+K +LR  R      P P
Sbjct: 426 LDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHLGQ-PSP 484

Query: 61  ---RTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLT 95
              R L ++A ++A G  +L  N+F+H D+A RNCLL+
Sbjct: 485 LVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLS 522


>gi|42544153 leukocyte receptor tyrosine kinase isoform 1 precursor
           [Homo sapiens]
          Length = 864

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 34/98 (34%), Positives = 54/98 (55%), Gaps = 4/98 (4%)

Query: 1   MQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDP 60
           + FL E       +H N+++C+      TP L+++E    GD+K +LR  R      P P
Sbjct: 556 LDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHLGQ-PSP 614

Query: 61  ---RTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLT 95
              R L ++A ++A G  +L  N+F+H D+A RNCLL+
Sbjct: 615 LVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLS 652


>gi|46249416 leukocyte receptor tyrosine kinase isoform 2 precursor
           [Homo sapiens]
          Length = 803

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 34/98 (34%), Positives = 54/98 (55%), Gaps = 4/98 (4%)

Query: 1   MQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDP 60
           + FL E       +H N+++C+      TP L+++E    GD+K +LR  R      P P
Sbjct: 495 LDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHLGQ-PSP 553

Query: 61  ---RTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLT 95
              R L ++A ++A G  +L  N+F+H D+A RNCLL+
Sbjct: 554 LVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLS 591


>gi|54607018 RYK receptor-like tyrosine kinase isoform 2 [Homo
           sapiens]
          Length = 607

 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 37/103 (35%), Positives = 55/103 (53%), Gaps = 4/103 (3%)

Query: 4   LEEVQPYRALKHSNLLQCLAQCAEVTPY-LLVMEFCPLGDLKGYLRSCRVAESMAPDP-- 60
           L E    R L H NLL     C E     ++++ +   G+LK +LR C++ E+  P    
Sbjct: 379 LTESCKLRGLHHRNLLPITHVCIEEGEKPMVILPYMNWGNLKLFLRQCKLVEANNPQAIS 438

Query: 61  -RTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
            + L  MA ++ACG+ +L R   +H DLA RNC++   L VKI
Sbjct: 439 QQDLVHMAIQIACGMSYLARREVIHKDLAARNCVIDDTLQVKI 481


>gi|54607020 RYK receptor-like tyrosine kinase isoform 1 [Homo
           sapiens]
          Length = 610

 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 37/103 (35%), Positives = 55/103 (53%), Gaps = 4/103 (3%)

Query: 4   LEEVQPYRALKHSNLLQCLAQCAEVTPY-LLVMEFCPLGDLKGYLRSCRVAESMAPDP-- 60
           L E    R L H NLL     C E     ++++ +   G+LK +LR C++ E+  P    
Sbjct: 382 LTESCKLRGLHHRNLLPITHVCIEEGEKPMVILPYMNWGNLKLFLRQCKLVEANNPQAIS 441

Query: 61  -RTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKI 102
            + L  MA ++ACG+ +L R   +H DLA RNC++   L VKI
Sbjct: 442 QQDLVHMAIQIACGMSYLARREVIHKDLAARNCVIDDTLQVKI 484


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.132    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,820,501
Number of Sequences: 37866
Number of extensions: 696878
Number of successful extensions: 8099
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 384
Number of HSP's successfully gapped in prelim test: 547
Number of HSP's that attempted gapping in prelim test: 5918
Number of HSP's gapped (non-prelim): 2127
length of query: 243
length of database: 18,247,518
effective HSP length: 99
effective length of query: 144
effective length of database: 14,498,784
effective search space: 2087824896
effective search space used: 2087824896
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.