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Search of human proteins with 119395742
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|119395742 integrin alpha chain, alpha 6 isoform b precursor
[Homo sapiens]
(1073 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 2172 0.0
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 2118 0.0
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 1027 0.0
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 990 0.0
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 902 0.0
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 650 0.0
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 631 0.0
gi|49170034 integrin, alpha 8 [Homo sapiens] 369 e-102
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 333 4e-91
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 318 2e-86
gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 315 1e-85
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 307 3e-83
gi|56237029 integrin alpha 5 precursor [Homo sapiens] 305 2e-82
gi|67191027 integrin alpha 4 precursor [Homo sapiens] 286 9e-77
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 236 9e-62
gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 218 3e-56
gi|116295258 integrin alpha 2 precursor [Homo sapiens] 204 4e-52
gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 188 3e-47
gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 181 3e-45
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 157 7e-38
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 155 1e-37
gi|148728188 integrin, alpha E precursor [Homo sapiens] 148 2e-35
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 142 2e-33
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 139 2e-32
gi|34452173 integrin alpha X precursor [Homo sapiens] 137 4e-32
gi|62548866 integrin, alpha D precursor [Homo sapiens] 127 6e-29
gi|29171717 glycosylphosphatidylinositol specific phospholipase ... 59 2e-08
gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ... 39 0.034
gi|109891938 disks large-associated protein 4 isoform c [Homo sa... 35 0.50
gi|34335251 disks large-associated protein 4 isoform b [Homo sap... 35 0.50
>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo
sapiens]
Length = 1073
Score = 2172 bits (5628), Expect = 0.0
Identities = 1073/1073 (100%), Positives = 1073/1073 (100%)
Query: 1 MAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKR 60
MAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKR
Sbjct: 1 MAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKR 60
Query: 61 LLLVGAPRAEALPLQRANRTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQ 120
LLLVGAPRAEALPLQRANRTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQ
Sbjct: 61 LLLVGAPRAEALPLQRANRTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQ 120
Query: 121 SQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLR 180
SQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLR
Sbjct: 121 SQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLR 180
Query: 181 GHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVG 240
GHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVG
Sbjct: 181 GHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVG 240
Query: 241 GETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAH 300
GETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAH
Sbjct: 241 GETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAH 300
Query: 301 LLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGR 360
LLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGR
Sbjct: 301 LLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGR 360
Query: 361 WNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTK 420
WNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTK
Sbjct: 361 WNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTK 420
Query: 421 PTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNR 480
PTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNR
Sbjct: 421 PTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNR 480
Query: 481 IDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFR 540
IDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFR
Sbjct: 481 IDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFR 540
Query: 541 NQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSL 600
NQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSL
Sbjct: 541 NQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSL 600
Query: 601 PEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKG 660
PEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKG
Sbjct: 601 PEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKG 660
Query: 661 VPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFP 720
VPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFP
Sbjct: 661 VPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFP 720
Query: 721 EKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQD 780
EKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQD
Sbjct: 721 EKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQD 780
Query: 781 NLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLG 840
NLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLG
Sbjct: 781 NLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLG 840
Query: 841 KPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRK 900
KPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRK
Sbjct: 841 KPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRK 900
Query: 901 KREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNST 960
KREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNST
Sbjct: 901 KREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNST 960
Query: 961 FLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILV 1020
FLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILV
Sbjct: 961 FLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILV 1020
Query: 1021 AILAGILMLALLVFILWKCGFFKRNKKDHYDATYHKAEIHAQPSDKERLTSDA 1073
AILAGILMLALLVFILWKCGFFKRNKKDHYDATYHKAEIHAQPSDKERLTSDA
Sbjct: 1021 AILAGILMLALLVFILWKCGFFKRNKKDHYDATYHKAEIHAQPSDKERLTSDA 1073
>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo
sapiens]
Length = 1091
Score = 2118 bits (5489), Expect = 0.0
Identities = 1048/1062 (98%), Positives = 1051/1062 (98%)
Query: 1 MAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKR 60
MAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKR
Sbjct: 1 MAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKR 60
Query: 61 LLLVGAPRAEALPLQRANRTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQ 120
LLLVGAPRAEALPLQRANRTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQ
Sbjct: 61 LLLVGAPRAEALPLQRANRTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQ 120
Query: 121 SQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLR 180
SQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLR
Sbjct: 121 SQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLR 180
Query: 181 GHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVG 240
GHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVG
Sbjct: 181 GHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVG 240
Query: 241 GETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAH 300
GETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAH
Sbjct: 241 GETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAH 300
Query: 301 LLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGR 360
LLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGR
Sbjct: 301 LLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGR 360
Query: 361 WNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTK 420
WNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTK
Sbjct: 361 WNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTK 420
Query: 421 PTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNR 480
PTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNR
Sbjct: 421 PTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNR 480
Query: 481 IDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFR 540
IDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFR
Sbjct: 481 IDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFR 540
Query: 541 NQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSL 600
NQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSL
Sbjct: 541 NQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSL 600
Query: 601 PEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKG 660
PEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKG
Sbjct: 601 PEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKG 660
Query: 661 VPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFP 720
VPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFP
Sbjct: 661 VPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFP 720
Query: 721 EKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQD 780
EKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQD
Sbjct: 721 EKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQD 780
Query: 781 NLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLG 840
NLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLG
Sbjct: 781 NLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLG 840
Query: 841 KPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRK 900
KPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRK
Sbjct: 841 KPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRK 900
Query: 901 KREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNST 960
KREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNST
Sbjct: 901 KREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNST 960
Query: 961 FLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILV 1020
FLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILV
Sbjct: 961 FLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILV 1020
Query: 1021 AILAGILMLALLVFILWKCGFFKRNKKDHYDATYHKAEIHAQ 1062
AILAGILMLALLVFILWKCGFFKR++ D YH I +
Sbjct: 1021 AILAGILMLALLVFILWKCGFFKRSRYDDSVPRYHAVRIRKE 1062
>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 1141
Score = 1027 bits (2655), Expect = 0.0
Identities = 534/1086 (49%), Positives = 733/1086 (67%), Gaps = 40/1086 (3%)
Query: 4 AGQLCLLY--LSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRL 61
A +C L+ L LL AFNLD +RK G+PGSLFGFS+A+H QLQP +
Sbjct: 12 ASGICYLFGSLLVELLFSRAVAFNLDVM--GALRKEGEPGSLFGFSVALHRQLQPRPQSW 69
Query: 62 LLVGAPRAEALPLQRANRTGGLYSCDITARGP-CTRIEFDNDADPTSESKEDQWMGVTVQ 120
LLVGAP+A ALP Q+ANRTGGL++C ++ C R++ D AD ESKE+QW+GV+V+
Sbjct: 70 LLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVR 129
Query: 121 SQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLR 180
SQGPGGK+VTCAHRYE RQ V+ E+RD+ GRC+VLSQ+L I D++DGG+W FC+GR +
Sbjct: 130 SQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQ 189
Query: 181 GHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVG 240
GHE+FG CQQG AA F+ D HY++FGAPGTYNWKG RVE D+ +DGPYE G
Sbjct: 190 GHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAG 249
Query: 241 GETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAH 300
GE E D L+PVPANSY GFS+DSGKG+V +E++FV+GAPRANH GAVV+L++D ++
Sbjct: 250 GEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKD-SASR 308
Query: 301 LLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGR 360
L+PE + GE L S FGY +AV DLN DGW D+++GAP +F+R E+GGAVYVY+NQ G
Sbjct: 309 LVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGH 368
Query: 361 WNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTK 420
W + P+RL G+ DSMFGI++ +GD+NQDG+PDIAVGAP+D GKVFIYHGS+ G+ K
Sbjct: 369 WAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAK 428
Query: 421 PTQVLKGIS---PYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVT 477
P+QVL+G + FGYS++G++D+D N YPD+ VGSL+D+ +FR+RP++++ +++
Sbjct: 429 PSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIA 488
Query: 478 PNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRV 537
P IDL Q G S +C+ ++ CF Y A P+ Y+P++++ L+A+ +RR G RV
Sbjct: 489 PRSIDLEQPNCAGGHS-VCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRV 547
Query: 538 QFRNQG-SEPKYTQELT--LKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSR 594
F ++ EPK+ T LK Q +VC + LQ+N++DKLR I +T S +Q P R
Sbjct: 548 TFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLR 607
Query: 595 RRV--NSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKL-EYKFCTREGNQDK 651
R+ LP V PILN+ +P T ++HFLK+GCG+D +C SNL+L +FCTR + +
Sbjct: 608 RQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTE- 666
Query: 652 FSYLPIQ-KGVPEL-VLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLT 709
F LP+ G L L Q I LE+ VTN PS+P P DGDDAHEA+L+ PD+L
Sbjct: 667 FQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLH 726
Query: 710 YSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDI 769
YS R L P ++ C++N+N S +CELGNP KR + VTFYL+LST+ ++ +T +L++
Sbjct: 727 YSGVRALD--PAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEV 784
Query: 770 NLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSL 829
L L T S Q+ L P++A+A+V IEL LS++G+A P Q++F G V GE+AM+SE +VGS
Sbjct: 785 ELLLATISEQE-LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSK 843
Query: 830 IEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKG----LEKVTCEPQK 885
++YE V N G+ L LG+A LNI WP EI+NGKWLLY ++VE +G +K C P+
Sbjct: 844 VKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRP 903
Query: 886 EINSLNLTESHNSRKKREITEKQIDDNRK--------FSLFAERKYQTLNCS-VNVNCVN 936
I L++ R++ E E+Q R+ S ++K TL+C+ NCV
Sbjct: 904 NILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVV 963
Query: 937 IRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQ 996
CPL D A L + RLWNSTFLEEYS + L++++RA I V ++ +N+ L +A T
Sbjct: 964 FSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTV 1023
Query: 997 VRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNKKDHYDAT--- 1053
+ V V+ GVPWW+IL+A+LAG+L+LALLV +LWK GFFKR K H +AT
Sbjct: 1024 IPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK--HPEATVPQ 1081
Query: 1054 YHKAEI 1059
YH +I
Sbjct: 1082 YHAVKI 1087
>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
Length = 1137
Score = 990 bits (2559), Expect = 0.0
Identities = 524/1091 (48%), Positives = 726/1091 (66%), Gaps = 54/1091 (4%)
Query: 4 AGQLCLLY--LSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRL 61
A +C L+ L LL AFNLD +RK G+PGSLFGFS+A+H QLQP +
Sbjct: 12 ASGICYLFGSLLVELLFSRAVAFNLDVM--GALRKEGEPGSLFGFSVALHRQLQPRPQSW 69
Query: 62 LLVGAPRAEALPLQRANRTGGLYSCDITARGP-CTRIEFDNDADPTSESKEDQWMGVTVQ 120
LLVGAP+A ALP Q+ANRTGGL++C ++ C R++ D AD ESKE+QW+GV+V+
Sbjct: 70 LLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVR 129
Query: 121 SQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLR 180
SQGPGGK+VTCAHRYE RQ V+ E+RD+ GRC+VLSQ+L I D++DGG+W FC+GR +
Sbjct: 130 SQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQ 189
Query: 181 GHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVG 240
GHE+FG CQQG AA F+ D HY++FGAPGTYNWKG++ F NI P ++
Sbjct: 190 GHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLL---------FVTNIDSSDPDQLV 240
Query: 241 GETEHDESLVPVPA-----NSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRD 295
+T +P PA NSYLGFS+DSGKG+V +E++FV+GAPRANH GAVV+L++D
Sbjct: 241 YKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKD 300
Query: 296 MKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYM 355
++ L+PE + GE L S FGY +AV DLN DGW D+++GAP +F+R E+GGAVYVY+
Sbjct: 301 -SASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYL 359
Query: 356 NQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSAN 415
NQ G W + P+RL G+ DSMFGI++ +GD+NQDG+PDIAVGAP+D GKVFIYHGS+
Sbjct: 360 NQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSL 419
Query: 416 GINTKPTQVLKGIS---PYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQK 472
G+ KP+QVL+G + FGYS++G++D+D N YPD+ VGSL+D+ +FR+RP++++
Sbjct: 420 GVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSH 479
Query: 473 TITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSG 532
+++ P IDL Q G S +C+ ++ CF Y A P+ Y+P++++ L+A+ +RR G
Sbjct: 480 EVSIAPRSIDLEQPNCAGGHS-VCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRG 538
Query: 533 LSSRVQFRNQG-SEPKYTQELT--LKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQ 589
RV F ++ EPK+ T LK Q +VC + LQ+N++DKLR I +T S +Q
Sbjct: 539 QVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQ 598
Query: 590 EPSSRRRV--NSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKL-EYKFCTRE 646
P RR+ LP V PILN+ +P T ++HFLK+GCG+D +C SNL+L +FCTR
Sbjct: 599 TPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRV 658
Query: 647 GNQDKFSYLPIQ-KGVPEL-VLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATF 704
+ + F LP+ G L L Q I LE+ VTN PS+P P DGDDAHEA+L+
Sbjct: 659 SDTE-FQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVML 717
Query: 705 PDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDT 764
PD+L YS R L P ++ C++N+N S +CELGNP KR + VTFYL+LST+ ++ +T
Sbjct: 718 PDSLHYSGVRALD--PAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIET 775
Query: 765 PDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSED 824
+L++ L L T S Q+ L P++A+A+V IEL LS++G+A P Q++F G V GE+AM+SE
Sbjct: 776 TELEVELLLATISEQE-LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSER 834
Query: 825 EVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKG----LEKVT 880
+VGS ++YE V N G+ L LG+A LNI WP EI+NGKWLLY ++VE +G +K
Sbjct: 835 DVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGL 894
Query: 881 CEPQKEINSLNLTESHNSRKKREITEKQIDDNRK--------FSLFAERKYQTLNCS-VN 931
C P+ I L++ R++ E E+Q R+ S ++K TL+C+
Sbjct: 895 CSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGT 954
Query: 932 VNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLP 991
NCV CPL D A L + RLWNSTFLEEYS + L++++RA I V ++ +N+ L
Sbjct: 955 ANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLR 1014
Query: 992 NAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNKKDHYD 1051
+A T + V V+ GVPWW+IL+A+LAG+L+LALLV +LWK GFFKR K H +
Sbjct: 1015 DASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK--HPE 1072
Query: 1052 AT---YHKAEI 1059
AT YH +I
Sbjct: 1073 ATVPQYHAVKI 1083
>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
Length = 1044
Score = 902 bits (2331), Expect = 0.0
Identities = 465/957 (48%), Positives = 644/957 (67%), Gaps = 35/957 (3%)
Query: 130 TCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEKFGSCQ 189
TCAHRYE RQ V+ E+RD+ GRC+VLSQ+L I D++DGG+W FC+GR +GHE+FG CQ
Sbjct: 42 TCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQ 101
Query: 190 QGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESL 249
QG AA F+ D HY++FGAPGTYNWKG RVE D+ +DGPYE GGE E D L
Sbjct: 102 QGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRL 161
Query: 250 VPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDG 309
+PVPANSY GFS+DSGKG+V +E++FV+GAPRANH GAVV+L++D ++ L+PE + G
Sbjct: 162 IPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKD-SASRLVPEVMLSG 220
Query: 310 EGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRL 369
E L S FGY +AV DLN DGW D+++GAP +F+R E+GGAVYVY+NQ G W + P+RL
Sbjct: 221 ERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRL 280
Query: 370 NGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLKGIS 429
G+ DSMFGI++ +GD+NQDG+PDIAVGAP+D GKVFIYHGS+ G+ KP+QVL+G +
Sbjct: 281 CGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEA 340
Query: 430 ---PYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQK 486
FGYS++G++D+D N YPD+ VGSL+D+ +FR+RP++++ +++ P IDL Q
Sbjct: 341 VGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQP 400
Query: 487 TACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQG-SE 545
G S +C+ ++ CF Y A P+ Y+P++++ L+A+ +RR G RV F ++ E
Sbjct: 401 NCAGGHS-VCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEE 459
Query: 546 PKYTQELT--LKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRV--NSLP 601
PK+ T LK Q +VC + LQ+N++DKLR I +T S +Q P RR+ LP
Sbjct: 460 PKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLP 519
Query: 602 EVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKL-EYKFCTREGNQDKFSYLPIQ-K 659
V PILN+ +P T ++HFLK+GCG+D +C SNL+L +FCTR + + F LP+
Sbjct: 520 PVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTE-FQPLPMDVD 578
Query: 660 GVPEL-VLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRA 718
G L L Q I LE+ VTN PS+P P DGDDAHEA+L+ PD+L YS R L
Sbjct: 579 GTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALD- 637
Query: 719 FPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSN 778
P ++ C++N+N S +CELGNP KR + VTFYL+LST+ ++ +T +L++ L L T S
Sbjct: 638 -PAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISE 696
Query: 779 QDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVIN 838
Q+ L P++A+A+V IEL LS++G+A P Q++F G V GE+AM+SE +VGS ++YE V N
Sbjct: 697 QE-LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSN 755
Query: 839 LGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKG----LEKVTCEPQKEINSLNLTE 894
G+ L LG+A LNI WP EI+NGKWLLY ++VE +G +K C P+ I L++
Sbjct: 756 QGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDS 815
Query: 895 SHNSRKKREITEKQIDDNRK--------FSLFAERKYQTLNCS-VNVNCVNIRCPLRGLD 945
R++ E E+Q R+ S ++K TL+C+ NCV CPL D
Sbjct: 816 RDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFD 875
Query: 946 SKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRVTVFPSK 1005
A L + RLWNSTFLEEYS + L++++RA I V ++ +N+ L +A T + V V+
Sbjct: 876 RAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDP 935
Query: 1006 TVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNKKDHYDAT---YHKAEI 1059
GVPWW+IL+A+LAG+L+LALLV +LWK GFFKR K H +AT YH +I
Sbjct: 936 MAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK--HPEATVPQYHAVKI 990
>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
Length = 1051
Score = 650 bits (1677), Expect = 0.0
Identities = 416/1094 (38%), Positives = 600/1094 (54%), Gaps = 87/1094 (7%)
Query: 7 LCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGA 66
LC L L + +AFNLDTR V+++ G+PGSLFG+S+A+H Q + + + LLL GA
Sbjct: 16 LCALALMVAAGGCVVSAFNLDTRF-LVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGA 74
Query: 67 PRAEALPLQRANRTGGLYSCDITA-RGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPG 125
PR A+P NRTG +Y C +TA + C R+ DP ED W+GVTV SQGP
Sbjct: 75 PRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIEDMWLGVTVASQGPA 134
Query: 126 GKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIE--DDMDGGDWSFCDGRLRGHE 183
G+V+ CAHRY + ++ + R + G+CYV +L ++ DD C+ +
Sbjct: 135 GRVLVCAHRYTQVLWSGSEDQRRMV-GKCYVRGNDLELDSSDDWQTYHNEMCNSNT-DYL 192
Query: 184 KFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGET 243
+ G CQ G + FT++ Y FGAPG YNWKG + Q+ ++D P + G
Sbjct: 193 ETGMCQLGTSGGFTQNTVY--FGAPGAYNWKGNSYMIQRKEWDLSEYSYKD-PEDQG--- 246
Query: 244 EHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLP 303
N Y+G+++ G I+ IT V+GAPR H GAV LL ++ L
Sbjct: 247 -----------NLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEA-GGDLRR 294
Query: 304 EHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNN 363
+ +G + + FG +A+ DLN DGWQD+++GAP YF+R EVGGA+YV+MNQ G
Sbjct: 295 RQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFP 354
Query: 364 VKP-IRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPT 422
P + L+G S FG++V +IGDINQDG+ DIAVGAP++ LGKV+IYH S+ G+ +P
Sbjct: 355 AHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQ 414
Query: 423 QVLKGIS------PYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINI-QKTIT 475
QV+ G FGYS++G MD+D N YPD+ VGSLSD + + R+RPVINI KT+
Sbjct: 415 QVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLV 474
Query: 476 VTPNRIDLRQKTACGAPSGICLQVKSCFEY--TANPAGYNPSISIVGTLEAEKERRKSGL 533
P +D C A S C+QV+ CF Y +A Y +I++ TLEA+++RR L
Sbjct: 475 PRPAVLD---PALCTATS--CVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRL 529
Query: 534 SSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITA--SVEIQEP 591
R GSE + + C + L L DN+RDKLRPI I+ S+ ++ P
Sbjct: 530 ------RFAGSESAVFHGFFSMPEMR--CQKLELLLMDNLRDKLRPIIISMNYSLPLRMP 581
Query: 592 SSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDK 651
R + PILN + H +V F KE CG DN C SNL++ F + + Q K
Sbjct: 582 DRPRLGLRSLDAYPILNQAQALENHTEVQFQKE-CGPDNKCESNLQMRAAFVSEQ--QQK 638
Query: 652 FSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYS 711
S L + V +L+L I VTN+ ++ R+ G+DAHEA L P L S
Sbjct: 639 LSRLQYSRDVRKLLLS--------INVTNTRTSERS----GEDAHEALLTLVVPPALLLS 686
Query: 712 AYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINL 771
+ R A C AN+ CELGNPFKRN + + VT T DL + L
Sbjct: 687 SVRPPGA-------CQANET---IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQL 736
Query: 772 KLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIE 831
+L T+S+QDNL P+ V L S+S V Q +FGGTV+GE MK+ ++VGS ++
Sbjct: 737 QLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLK 796
Query: 832 YEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKE-INSL 890
YEF+V +G+ L LGT L ++WP E+SNGKWLLY ++ G C P + IN L
Sbjct: 797 YEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPL 856
Query: 891 NLT-------ESHNSRKKREITEKQIDDNRKFSLFAERKYQT---LNCSV-NVNCVNIRC 939
NLT S R++R++ +L A +K ++ L C+ +CV + C
Sbjct: 857 NLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLEC 916
Query: 940 PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRV 999
P+ ++ +++R+WNSTF+E+Y + + + A + + + I + N T V
Sbjct: 917 PIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSV 976
Query: 1000 TVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNK-KDHYDATYHKAE 1058
+ + + W++LVA+ AG+L+L L++ +LWKCGFFKR + + Y+A KAE
Sbjct: 977 DIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRARTRALYEAKRQKAE 1036
Query: 1059 IHAQPSDKERLTSD 1072
+ +QPS+ ERLT D
Sbjct: 1037 MKSQPSETERLTDD 1050
>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
Length = 1066
Score = 631 bits (1628), Expect = 0.0
Identities = 405/1083 (37%), Positives = 585/1083 (54%), Gaps = 86/1083 (7%)
Query: 7 LCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGA 66
LC L L + +AFNLDTR V+++ G+PGSLFG+S+A+H Q + + + LLL GA
Sbjct: 16 LCALALMVAAGGCVVSAFNLDTRF-LVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGA 74
Query: 67 PRAEALPLQRANRTGGLYSCDITA-RGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPG 125
PR A+P NRTG +Y C +TA + C R+ DP ED W+GVTV SQGP
Sbjct: 75 PRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIEDMWLGVTVASQGPA 134
Query: 126 GKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIE--DDMDGGDWSFCDGRLRGHE 183
G+V+ CAHRY + ++ + R + G+CYV +L ++ DD C+ +
Sbjct: 135 GRVLVCAHRYTQVLWSGSEDQRRMV-GKCYVRGNDLELDSSDDWQTYHNEMCNSNT-DYL 192
Query: 184 KFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGET 243
+ G CQ G + FT++ Y FGAPG YNWKG + Q+ ++D P + G
Sbjct: 193 ETGMCQLGTSGGFTQNTVY--FGAPGAYNWKGNSYMIQRKEWDLSEYSYKD-PEDQG--- 246
Query: 244 EHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLP 303
N Y+G+++ G I+ IT V+GAPR H GAV LL ++ L
Sbjct: 247 -----------NLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEA-GGDLRR 294
Query: 304 EHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNN 363
+ +G + + FG +A+ DLN DGWQD+++GAP YF+R EVGGA+YV+MNQ G
Sbjct: 295 RQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFP 354
Query: 364 VKP-IRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPT 422
P + L+G S FG++V +IGDINQDG+ DIAVGAP++ LGKV+IYH S+ G+ +P
Sbjct: 355 AHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQ 414
Query: 423 QVLKGIS------PYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINI-QKTIT 475
QV+ G FGYS++G MD+D N YPD+ VGSLSD + + R+RPVINI KT+
Sbjct: 415 QVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLV 474
Query: 476 VTPNRIDLRQKTACGAPSGICLQVKSCFEY--TANPAGYNPSISIVGTLEAEKERRKSGL 533
P +D C A S C+QV+ CF Y +A Y +I++ TLEA+++RR L
Sbjct: 475 PRPAVLD---PALCTATS--CVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRL 529
Query: 534 SSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITA--SVEIQEP 591
R GSE + + C + L L DN+RDKLRPI I+ S+ ++ P
Sbjct: 530 ------RFAGSESAVFHGFFSMPEMR--CQKLELLLMDNLRDKLRPIIISMNYSLPLRMP 581
Query: 592 SSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDK 651
R + PILN + H +V F KE CG DN C SNL++ F + + Q K
Sbjct: 582 DRPRLGLRSLDAYPILNQAQALENHTEVQFQKE-CGPDNKCESNLQMRAAFVSEQ--QQK 638
Query: 652 FSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYS 711
S L + V +L+L I VTN+ ++ R+ G+DAHEA L P L S
Sbjct: 639 LSRLQYSRDVRKLLLS--------INVTNTRTSERS----GEDAHEALLTLVVPPALLLS 686
Query: 712 AYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINL 771
+ R A C AN+ CELGNPFKRN + + VT T DL + L
Sbjct: 687 SVRPPGA-------CQANET---IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQL 736
Query: 772 KLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIE 831
+L T+S+QDNL P+ V L S+S V Q +FGGTV+GE MK+ ++VGS ++
Sbjct: 737 QLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLK 796
Query: 832 YEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKE-INSL 890
YEF+V +G+ L LGT L ++WP E+SNGKWLLY ++ G C P + IN L
Sbjct: 797 YEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPL 856
Query: 891 NLT-------ESHNSRKKREITEKQIDDNRKFSLFAERKYQT---LNCSV-NVNCVNIRC 939
NLT S R++R++ +L A +K ++ L C+ +CV + C
Sbjct: 857 NLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLEC 916
Query: 940 PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRV 999
P+ ++ +++R+WNSTF+E+Y + + + A + + + I + N T V
Sbjct: 917 PIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSV 976
Query: 1000 TVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNKKDHYDATYHKAEI 1059
+ + + W++LVA+ AG+L+L L++ +LWKC FFKR + YH I
Sbjct: 977 DIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCDFFKRTRYYQIMPKYHAVRI 1036
Query: 1060 HAQ 1062
+
Sbjct: 1037 REE 1039
>gi|49170034 integrin, alpha 8 [Homo sapiens]
Length = 1063
Score = 369 bits (948), Expect = e-102
Identities = 315/1119 (28%), Positives = 519/1119 (46%), Gaps = 133/1119 (11%)
Query: 7 LCLLYLSAGLL--SRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLV 64
LC + G+L S AFNLD + V G GS FG+++ H + +LV
Sbjct: 20 LCCAAAALGMLLWSPACQAFNLDVEKLTVYS--GPKGSYFGYAVDFH--IPDARTASVLV 75
Query: 65 GAPRAEALPLQRANRTGGLYSCDITARGP--CTRIEFD---------NDADPTSESKEDQ 113
GAP+A G +Y C A G C +I FD N E K +Q
Sbjct: 76 GAPKANTSQPDIVEG-GAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKEPIEFKSNQ 134
Query: 114 WMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWS 173
W G TV++ GKVV CA Y R T + +D G CYV QN ++S
Sbjct: 135 WFGATVKAHK--GKVVACAPLYHWRTLKPTPE--KDPVGTCYVAIQNFSAY-----AEFS 185
Query: 174 FCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFE 233
C E G CQ G + F K+ IV G PG++ W+G V + + + F+
Sbjct: 186 PCRNSNADPEGQGYCQAGFSLDFYKNGDLIV-GGPGSFYWQGQVITASVADIIANYS-FK 243
Query: 234 DGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLK 293
D ++ GE + + + +SYLG+S+ +G+ + V+G PR + V +
Sbjct: 244 DILRKLAGEKQTEVAPASYD-DSYLGYSVAAGE-FTGDSQQELVAGIPRGAQNFGYVSI- 300
Query: 294 RDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVG----G 349
+ S + F GE +AS FGY V V D+N DG D+++GAP + +R+ E G
Sbjct: 301 --INSTDMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVG 358
Query: 350 AVYVYMNQQGRWNNVKPIRLNGTKD-SMFGIAVKNIGDINQDGYPDIAVGAPY---DDLG 405
+Y+Y+ P L GT+ FG A+ ++GD+NQDGY DIA+G P+ D G
Sbjct: 359 QIYLYLQVSSLLFR-DPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRG 417
Query: 406 KVFIYHGSANGINTKPTQVLKGI------SPYFGYSIAGNMDLDRNSYPDVAVGSL-SDS 458
KV IY+G+ +G+NTKP+QVL+G+ FG+++ G+ D+D+N YPD+ VG+ +
Sbjct: 418 KVLIYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGK 477
Query: 459 VTIFRSRPVINIQKTITVTPNRIDLRQKTACGAP----SGICLQVKSCFEYTANPAGYNP 514
V ++R+RPV+ + + + P I+L KT C P S C ++ C T
Sbjct: 478 VAVYRARPVVTVDAQLLLHPMIINLENKT-CQVPDSMTSAACFSLRVCASVTGQSIAN-- 534
Query: 515 SISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDN-- 572
+I ++ ++ + ++K + + N + + L +KRQK C + ++L+D
Sbjct: 535 TIVLMAEVQLDSLKQKGAIKRTLFLDNHQAHRVFP--LVIKRQKSHQCQDFIVYLRDETE 592
Query: 573 IRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVC 632
RDKL PI I+ + + E + + + EV PILN H L + CG+DN+C
Sbjct: 593 FRDKLSPINISLNYSLDESTFKEGL----EVKPILNYYRENIVSEQAHILVD-CGEDNLC 647
Query: 633 NSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDG 692
+LKL + DK ++++ D+ + L I N +G
Sbjct: 648 VPDLKLSAR-------PDKH----------QVIIGDENHLMLIINARN----------EG 680
Query: 693 DDAHEAKLIATFPDTLTYSAY-RELRAFPEKQLSCVANQNG--SQADCELGNPFKRNSNV 749
+ A+EA+L P+ Y R + F + LSC C+LGNP +N
Sbjct: 681 EGAYEAELFVMIPEEADYVGIERNNKGF--RPLSCEYKMENVTRMVVCDLGNPMVSGTNY 738
Query: 750 TFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAP--ITAKAKVVIELLLSVSGVAKPSQ 807
+ L + + ++ +L++ + SN+DN ++ + + + + GV+ P Q
Sbjct: 739 SLGLRFAVPRLEKTNMSINFDLQIRS-SNKDNPDSNFVSLQINITAVAQVEIRGVSHPPQ 797
Query: 808 VYFG-GTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLL 866
+ E+ E+EVG L+E+ + + N+G + + L + WP + ++LL
Sbjct: 798 IVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGP--STISDTILEVGWPFS-ARDEFLL 854
Query: 867 YLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITE----------KQIDDNRKFS 916
Y+ +++ G + C+P IN ++ + + E++ + D
Sbjct: 855 YIFHIQTLG--PLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVE 912
Query: 917 LFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLIL--RSRLWNSTFLEEYSKLNYLDIL 974
+ + LNC+ N+ C+ I C + L+ S +L RSRLW TFL+ + L L
Sbjct: 913 FHRQSPAKILNCT-NIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALASL 971
Query: 975 MRAFIDVTAAAEN-IRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLV 1033
+ + + +LP ++ +V + +S +P W+I++AIL G+L+LA+L
Sbjct: 972 VSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFS-IPLWVIILAILLGLLVLAILT 1030
Query: 1034 FILWKCGFFKRNKKDHYDATYHKAEIHAQPSDKERLTSD 1072
LWKCGFF R + D T D+E+LT+D
Sbjct: 1031 LALWKCGFFDRARPPQEDMT-----------DREQLTND 1058
>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
Length = 1048
Score = 333 bits (855), Expect = 4e-91
Identities = 302/1075 (28%), Positives = 507/1075 (47%), Gaps = 112/1075 (10%)
Query: 12 LSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEA 71
L +GLL L AFNLD D+ G GS FGF++ + + LLVGAP+A
Sbjct: 19 LLSGLLLPLCRAFNLDV--DSPAEYSGPEGSYFGFAVDF-FVPSASSRMFLLVGAPKANT 75
Query: 72 LPLQRANRTGG-LYSCDITARGPCTRIEFDNDA------DPTSESKEDQWMGVTVQSQGP 124
Q GG + CD ++ C IEFD D E K QW G +V+S+
Sbjct: 76 T--QPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQD 133
Query: 125 GGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEK 184
K++ CA Y R + KQE R+ G C+ ++D +++ C + +
Sbjct: 134 --KILACAPLYHWRTEM--KQE-REPVGTCF-------LQDGTKTVEYAPCRSQDIDADG 181
Query: 185 FGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTF--FDMNIFEDGPYEVGGE 242
G CQ G + FTK ++ G PG++ W+G + +Q +D N++ Y
Sbjct: 182 QGFCQGGFSIDFTKADR-VLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSI-KYNNQLA 239
Query: 243 TEHDESLVPVPANSYLGFSLDSGKGIVSKDEIT-FVSGAPRANHSGAVVLLKRDMKSAHL 301
T +++ +SYLG+S+ G + D I FVSG PRA + +V + + L
Sbjct: 240 TRTAQAIFD---DSYLGYSVAVGD--FNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL 294
Query: 302 LPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDR--DGEVGGAVYVYMNQQG 359
+ F GE +A+ FG+ VA D+N D + D+ IGAP + DR DG++ V ++ Q
Sbjct: 295 ---YNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQR 351
Query: 360 RWNNVKPIRLNGTKD-SMFGIAVKNIGDINQDGYPDIAVGAPY---DDLGKVFIYHGSAN 415
+ + +LNG + + FG A+ +GD++QDG+ DIA+ APY D G V+I++G +
Sbjct: 352 ASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRST 411
Query: 416 GINTKPTQVLKG------ISPYFGYSIAGNMDLDRNSYPDVAVGSLS-DSVTIFRSRPVI 468
G+N P+Q+L+G + P FGYS+ G D+D+N YPD+ VG+ D ++R+RPVI
Sbjct: 412 GLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVI 471
Query: 469 NIQKTITVTPNRIDLRQKTACGAPSGI----CLQVKSCFEYTANPAGYNP-SISIVGTLE 523
+ + V P+ ++ KT C P C V+ C + A+ G P ++ L
Sbjct: 472 TVNAGLEVYPSILNQDNKT-CSLPGTALKVSCFNVRFCLK--ADGKGVLPRKLNFQVELL 528
Query: 524 AEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDN--IRDKLRPIP 581
+K ++K G R F S P +++ +T+ R C E +L+D RDKL PI
Sbjct: 529 LDKLKQK-GAIRRALFLYSRS-PSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPIT 586
Query: 582 ITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYK 641
I + R + PILN P H L + CG+DNVC L++
Sbjct: 587 IFMEYRLDY----RTAADTTGLQPILNQFTPANISRQAHILLD-CGEDNVCKPKLEVSV- 640
Query: 642 FCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLI 701
+ +Q K + + D + L + N G+ A+EA+LI
Sbjct: 641 ----DSDQKK------------IYIGDDNPLTLIVKAQNQ----------GEGAYEAELI 674
Query: 702 ATFPDTLTY-SAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEV 760
+ P + R A + Q C+LGNP K + + L S +
Sbjct: 675 VSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQ 734
Query: 761 TFDTPDLDINLKLETTSNQDNLAPITA-KAKVVIELLLSVSGVAKPSQVYFG-GTVVGEQ 818
+ + +L++++++ D ++P+ + K + + + + GV+ P ++ ++
Sbjct: 735 SEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKE 794
Query: 819 AMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEK 878
++E++VG ++++ + + N G ++ A L++QWP + +N LLY++ + G
Sbjct: 795 NPETEEDVGPVVQHIYELRNNGP--SSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG--P 849
Query: 879 VTCEPQKEINSLNLTESHNSRKKREIT-----EKQIDDNRKFSLFAERKYQTLNCSVNVN 933
+ C EIN L + S ++ T E+ ++ +E TL C V
Sbjct: 850 MNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGV-AQ 908
Query: 934 CVNIRCPLRGLDSKASLIL--RSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAA-ENIRL 990
C+ I C + LD S IL +S LW TF+ + ++ + + A +V +N+ +
Sbjct: 909 CLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPI 968
Query: 991 PNAGTQVRVTVFPSKTVAQYS-GVPWWIILVAILAGILMLALLVFILWKCGFFKR 1044
+ VT + + VP W+I++A+LAG+L+LA+LVF++++ GFFKR
Sbjct: 969 EDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKR 1023
>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
Length = 1002
Score = 318 bits (815), Expect = 2e-86
Identities = 285/1028 (27%), Positives = 485/1028 (47%), Gaps = 109/1028 (10%)
Query: 59 KRLLLVGAPRAEALPLQRANRTGG-LYSCDITARGPCTRIEFDNDA------DPTSESKE 111
+ LLVGAP+A Q GG + CD ++ C IEFD D E K
Sbjct: 17 RMFLLVGAPKANTT--QPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS 74
Query: 112 DQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGD 171
QW G +V+S+ K++ CA Y R + KQE R+ G C+ ++D +
Sbjct: 75 HQWFGASVRSKQD--KILACAPLYHWRTEM--KQE-REPVGTCF-------LQDGTKTVE 122
Query: 172 WSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTF--FDM 229
++ C + + G CQ G + FTK ++ G PG++ W+G + +Q +D
Sbjct: 123 YAPCRSQDIDADGQGFCQGGFSIDFTKADR-VLLGGPGSFYWQGQLISDQVAEIVSKYDP 181
Query: 230 NIFEDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEIT-FVSGAPRANHSGA 288
N++ Y T +++ +SYLG+S+ G + D I FVSG PRA +
Sbjct: 182 NVYSI-KYNNQLATRTAQAIFD---DSYLGYSVAVGD--FNGDGIDDFVSGVPRAARTLG 235
Query: 289 VVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDR--DGE 346
+V + + L + F GE +A+ FG+ VA D+N D + D+ IGAP + DR DG+
Sbjct: 236 MVYIYDGKNMSSL---YNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGK 292
Query: 347 VGGAVYVYMNQQGRWNNVKPIRLNGTKD-SMFGIAVKNIGDINQDGYPDIAVGAPY---D 402
+ V ++ Q + + +LNG + + FG A+ +GD++QDG+ DIA+ APY D
Sbjct: 293 LQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGED 352
Query: 403 DLGKVFIYHGSANGINTKPTQVLKG------ISPYFGYSIAGNMDLDRNSYPDVAVGSLS 456
G V+I++G + G+N P+Q+L+G + P FGYS+ G D+D+N YPD+ VG+
Sbjct: 353 KKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFG 412
Query: 457 -DSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGI----CLQVKSCFEYTANPAG 511
D ++R+RPVI + + V P+ ++ KT C P C V+ C + A+ G
Sbjct: 413 VDRAILYRARPVITVNAGLEVYPSILNQDNKT-CSLPGTALKVSCFNVRFCLK--ADGKG 469
Query: 512 YNP-SISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQ 570
P ++ L +K ++K G R F S P +++ +T+ R C E +L+
Sbjct: 470 VLPRKLNFQVELLLDKLKQK-GAIRRALFLYSRS-PSHSKNMTISRGGLMQCEELIAYLR 527
Query: 571 DN--IRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGD 628
D RDKL PI I + R + PILN P H L + CG+
Sbjct: 528 DESEFRDKLTPITIFMEYRLDY----RTAADTTGLQPILNQFTPANISRQAHILLD-CGE 582
Query: 629 DNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNP 688
DNVC L++ + +Q K + + D + L + N
Sbjct: 583 DNVCKPKLEVSV-----DSDQKK------------IYIGDDNPLTLIVKAQNQ------- 618
Query: 689 TKDGDDAHEAKLIATFPDTLTY-SAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNS 747
G+ A+EA+LI + P + R A + Q C+LGNP K +
Sbjct: 619 ---GEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGT 675
Query: 748 NVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPITA-KAKVVIELLLSVSGVAKPS 806
+ L S + + + +L++++++ D ++P+ + K + + + + GV+ P
Sbjct: 676 QLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPD 735
Query: 807 QVYFG-GTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWL 865
++ ++ ++E++VG ++++ + + N G ++ A L++QWP + +N L
Sbjct: 736 HIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGP--SSFSKAMLHLQWPYKYNNNT-L 792
Query: 866 LYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREIT-----EKQIDDNRKFSLFAE 920
LY++ + G + C EIN L + S ++ T E+ ++ +E
Sbjct: 793 LYILHYDIDG--PMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSE 850
Query: 921 RKYQTLNCSVNVNCVNIRCPLRGLDSKASLIL--RSRLWNSTFLEEYSKLNYLDILMRAF 978
TL C V C+ I C + LD S IL +S LW TF+ + ++ + + A
Sbjct: 851 GDIHTLGCGV-AQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSAS 909
Query: 979 IDVTAAA-ENIRLPNAGTQVRVTVFPSKTVAQYS-GVPWWIILVAILAGILMLALLVFIL 1036
+V +N+ + + VT + + VP W+I++A+LAG+L+LA+LVF++
Sbjct: 910 FNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVM 969
Query: 1037 WKCGFFKR 1044
++ GFFKR
Sbjct: 970 YRMGFFKR 977
>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
Length = 1035
Score = 315 bits (807), Expect = 1e-85
Identities = 282/1098 (25%), Positives = 504/1098 (45%), Gaps = 127/1098 (11%)
Query: 4 AGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLL 63
AG+L L L+ + A+NLD + + G S FG+++ H+ ++ R +L
Sbjct: 10 AGRLRALLLALVVAGIPAGAYNLDPQRP--VHFQGPADSFFGYAVLEHFH---DNTRWVL 64
Query: 64 VGAPRAEALPLQRANRTGGLYSCDITARGP--CTRIEFDNDADPTS-------ESKEDQW 114
VGAP+A++ G ++ C + CT ++ + + E ++D+W
Sbjct: 65 VGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEW 124
Query: 115 MGVTVQSQGPG-GKVVTCAHRYEKRQHVNTKQESRDIF--GRCYVLSQNLRIEDDMDGGD 171
MGV++ Q G+V+ CAHR++ N E+ I G CY++ NL+ + G
Sbjct: 125 MGVSLARQPKADGRVLACAHRWK-----NIYYEADHILPHGFCYIIPSNLQAK----GRT 175
Query: 172 WSFC--DGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRV-EQKNNTFFD 228
C + + + E+ GSCQ G+A FT++ +V GAPG++ W G ++V +NT+
Sbjct: 176 LIPCYEEYKKKYGEEHGSCQAGIAGFFTEEL--VVMGAPGSFYWAGTIKVLNLTDNTYLK 233
Query: 229 MNIFEDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGA 288
+N + ++ +YLG+++ +G I V GAP+ G
Sbjct: 234 LN----------------DEVIMNRRYTYLGYAVTAGH-FSHPSTIDVVGGAPQDKGIGK 276
Query: 289 VVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVG 348
V + + D +S L+ G+ + S FG + VDLN DG D+++GAP + + E
Sbjct: 277 VYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDE-- 334
Query: 349 GAVYVYMNQ-QGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDD--LG 405
G V VY+N+ G + +G ++ FG ++ ++ D++ DG+PD+A+GAP +D G
Sbjct: 335 GQVTVYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAG 394
Query: 406 KVFIYHGSANGINTKPTQVLKG--ISP---YFGYSIAGNMDLDRNSYPDVAVGS-LSDSV 459
V+IYHG A GI + + L G I+P FG SI+G +D+D N YPDV VG+ +SDSV
Sbjct: 395 AVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSV 454
Query: 460 TIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGI-CLQVKSCFEYTANPAGYNPSISI 518
+ R+RPVI + +I + P I++ + CL V +CF + ++
Sbjct: 455 VLLRARPVITVDVSIFL-PGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPGEIGLNY 513
Query: 519 VGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLR 578
V L A+ +++ G RV F G E ++ C ++ ++D +
Sbjct: 514 V--LMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVKRRVQDVIS 571
Query: 579 PIPITASVEIQEPSSRRRVNSLPEVLPILN-SDEPKTAHIDVHFLKEGCGDDNVCNSNLK 637
PI A+ + E + LP + P+L K A + + C ++ C ++L+
Sbjct: 572 PIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSED-CAADLQ 630
Query: 638 LEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHE 697
L+ K +K Y L L K+I+L I+++N GDDA++
Sbjct: 631 LQGKLLL-SSMDEKTLY---------LALGAVKNISLNISISNL----------GDDAYD 670
Query: 698 AKLIATFPDTLTYSAYRELRAF-----PEKQLSCVANQNGSQADCELGNPFKRN-SNVTF 751
A ++++ REL E +SC ++ C +G PF R+ S F
Sbjct: 671 A--------NVSFNVSRELFFINMWQKEEMGISCELLES-DFLKCSVGFPFMRSKSKYEF 721
Query: 752 YLVLSTTEVTFDTPDLD--INLKLETTSNQDNLAPITAKAKVVI--ELLLSVSGVAKPSQ 807
++ T+ ++ + L + + T ++L T V + E+ S++G+ P+
Sbjct: 722 SVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTS 781
Query: 808 VYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATL-----NIQWPKEISNG 862
+G +V ++ +D +E F+ IN+ + N G +TL +I +P +S+G
Sbjct: 782 FVYGESVDAANFIQLDD-----LECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSG 836
Query: 863 KWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERK 922
++ V+ G EK C QK + + E++ + F+ F +
Sbjct: 837 GAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQ-----------EQENIFHTIFAFFTKSG 885
Query: 923 YQTLNC-SVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDV 981
+ L+C ++C+ C L + S + + +T + + + + + RA + V
Sbjct: 886 RKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKV 945
Query: 982 TAAAENIRLPNAGTQVRVTVFPSKTVAQYSG-VPWWIILVAILAGILMLALLVFILWKCG 1040
A + + + + VF + + G V WII +++L GIL+ LL +LWK G
Sbjct: 946 DPALRVVEIAHGNPEEVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMG 1005
Query: 1041 FFKRNKKDHYDATYHKAE 1058
FF+R K+ +A ++ E
Sbjct: 1006 FFRRRYKEIIEAEKNRKE 1023
>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
Length = 1012
Score = 307 bits (787), Expect = 3e-83
Identities = 294/1073 (27%), Positives = 490/1073 (45%), Gaps = 144/1073 (13%)
Query: 12 LSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEA 71
L +GLL L AFNLD D+ G GS FGF++ + + LLVGAP+A
Sbjct: 19 LLSGLLLPLCRAFNLDV--DSPAEYSGPEGSYFGFAVDF-FVPSASSRMFLLVGAPKANT 75
Query: 72 LPLQRANRTGG-LYSCDITARGPCTRIEFDNDA------DPTSESKEDQWMGVTVQSQGP 124
Q GG + CD ++ C IEFD D E K QW G +V+S+
Sbjct: 76 T--QPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQD 133
Query: 125 GGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEK 184
K++ CA Y R + KQE R+ G C+ ++D +++ C R +
Sbjct: 134 --KILACAPLYHWRTEM--KQE-REPVGTCF-------LQDGTKTVEYAPC----RSRQL 177
Query: 185 FGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETE 244
+ + + + + I YN + R Q IF+D
Sbjct: 178 ISDQVAEIVSKYDPNVYSI------KYNNQLATRTAQA--------IFDD---------- 213
Query: 245 HDESLVPVPANSYLGFSLDSGKGIVSKDEIT-FVSGAPRANHSGAVVLLKRDMKSAHLLP 303
SYLG+S+ G + D I FVSG PRA + +V + + L
Sbjct: 214 -----------SYLGYSVAVGD--FNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSL-- 258
Query: 304 EHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDR--DGEVGGAVYVYMNQQGRW 361
+ F GE +A+ FG+ VA D+N D + D+ IGAP + DR DG++ V ++ Q
Sbjct: 259 -YNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRAS 317
Query: 362 NNVKPIRLNGTKD-SMFGIAVKNIGDINQDGYPDIAVGAPY---DDLGKVFIYHGSANGI 417
+ + +LNG + + FG A+ +GD++QDG+ DIA+ APY D G V+I++G + G+
Sbjct: 318 GDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGL 377
Query: 418 NTKPTQVLKG------ISPYFGYSIAGNMDLDRNSYPDVAVGSLS-DSVTIFRSRPVINI 470
N P+Q+L+G + P FGYS+ G D+D+N YPD+ VG+ D ++R+RPVI +
Sbjct: 378 NAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITV 437
Query: 471 QKTITVTPNRIDLRQKTACGAPSGI----CLQVKSCFEYTANPAGYNP-SISIVGTLEAE 525
+ V P+ ++ KT C P C V+ C + A+ G P ++ L +
Sbjct: 438 NAGLEVYPSILNQDNKT-CSLPGTALKVSCFNVRFCLK--ADGKGVLPRKLNFQVELLLD 494
Query: 526 KERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDN--IRDKLRPIPIT 583
K ++K G R F S P +++ +T+ R C E +L+D RDKL PI I
Sbjct: 495 KLKQK-GAIRRALFLYSRS-PSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIF 552
Query: 584 ASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFC 643
+ R + PILN P H L + CG+DNVC L++
Sbjct: 553 MEYRLDY----RTAADTTGLQPILNQFTPANISRQAHILLD-CGEDNVCKPKLEVSV--- 604
Query: 644 TREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIAT 703
+ +Q K + + D + L + N G+ A+EA+LI +
Sbjct: 605 --DSDQKK------------IYIGDDNPLTLIVKAQNQ----------GEGAYEAELIVS 640
Query: 704 FPDTLTY-SAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTF 762
P + R A + Q C+LGNP K + + L S + +
Sbjct: 641 IPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSE 700
Query: 763 DTPDLDINLKLETTSNQDNLAPITA-KAKVVIELLLSVSGVAKPSQVYFG-GTVVGEQAM 820
+ +L++++++ D ++P+ + K + + + + GV+ P ++ ++
Sbjct: 701 MDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENP 760
Query: 821 KSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVT 880
++E++VG ++++ + + N G ++ A L++QWP + +N LLY++ + G +
Sbjct: 761 ETEEDVGPVVQHIYELRNNGP--SSFSKAMLHLQWPYKYNNNT-LLYILHYDIDG--PMN 815
Query: 881 CEPQKEINSLNLTESHNSRKKREIT-----EKQIDDNRKFSLFAERKYQTLNCSVNVNCV 935
C EIN L + S ++ T E+ ++ +E TL C V C+
Sbjct: 816 CTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGV-AQCL 874
Query: 936 NIRCPLRGLDSKASLIL--RSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAA-ENIRLPN 992
I C + LD S IL +S LW TF+ + ++ + + A +V +N+ + +
Sbjct: 875 KIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIED 934
Query: 993 AGTQVRVTVFPSKTVAQYS-GVPWWIILVAILAGILMLALLVFILWKCGFFKR 1044
VT + + VP W+I++A+LAG+L+LA+LVF++++ GFFKR
Sbjct: 935 ITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKR 987
>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
Length = 1049
Score = 305 bits (781), Expect = 2e-82
Identities = 310/1104 (28%), Positives = 489/1104 (44%), Gaps = 150/1104 (13%)
Query: 24 FNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQP-EDKRLLLVGAPRAEALPLQRANRTGG 82
FNLD V+ G PGS FGFS+ + +P D +LVGAP+A + G
Sbjct: 42 FNLDAEAPAVLS--GPPGSFFGFSVEFY---RPGTDGVSVLVGAPKANTSQ-PGVLQGGA 95
Query: 83 LYSCDITARGP-CTRIEFDNDADPTSES-------------KEDQWMGVTVQSQGPGGKV 128
+Y C A CT IEFD+ ES K QW G TV++ G +
Sbjct: 96 VYLCPWGASPTQCTPIEFDSKGSRLLESSLSSSEGEEPVEYKSLQWFGATVRAHG--SSI 153
Query: 129 VTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLR--IEDDMDGGDWSFCDGRLRGHEKFG 186
+ CA Y R K+ D G CY+ + N +E D+S+ G+ G
Sbjct: 154 LACAPLYSWRTE---KEPLSDPVGTCYLSTDNFTRILEYAPCRSDFSWAAGQ-------G 203
Query: 187 SCQQGVAATFTKDFHYIVFGAPGTYNWKGIV---RVEQKNNTFFDMNIFEDGPYEVGGET 243
CQ G +A FTK +V G PG+Y W+G + EQ +++ + V G+
Sbjct: 204 YCQGGFSAEFTKTGR-VVLGGPGSYFWQGQILSATQEQIAESYYPEYLIN----LVQGQL 258
Query: 244 EHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLP 303
+ ++ + +SYLG+S+ G+ D FV+G P+ N + V + + + +
Sbjct: 259 QTRQAS-SIYDDSYLGYSVAVGE-FSGDDTEDFVAGVPKGNLTYGYVTI---LNGSDIRS 313
Query: 304 EHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDR--DG--EVGGAVYVYMNQQG 359
+ F GE +AS FGY VA D+N DG D+++GAP DR DG + G VYVY+
Sbjct: 314 LYNFSGEQMASYFGYAVAATDVNGDGLDDLLVGAPLLMDRTPDGRPQEVGRVYVYLQHPA 373
Query: 360 RWNNVKPIRLNGTKD-SMFGIAVKNIGDINQDGYPDIAVGAPYD---DLGKVFIYHGSAN 415
+ L G + FG ++ +GD++QDGY D+A+GAP+ G VF++ G
Sbjct: 374 GIEPTPTLTLTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGPG 433
Query: 416 GINTKPTQVLKGI------SPYFGYSIAGNMDLDRNSYPDVAVGSLS-DSVTIFRSRPVI 468
G+ +KP+QVL+ + +FG ++ G DLD N YPD+ VGS D ++R RP++
Sbjct: 434 GLGSKPSQVLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPIV 493
Query: 469 NIQKTITVTPNRIDLRQKTAC--GAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEK 526
+ ++T+ P + +++ G P C+ + C N +G + + SI T+E +
Sbjct: 494 SASASLTIFPAMFNPEERSCSLEGNPVA-CINLSFCL----NASGKHVADSIGFTVELQL 548
Query: 527 ERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDN--IRDKLRPIPITA 584
+ +K R + TQ L ++ ++ C E ++L++ RDKL PI I
Sbjct: 549 DWQKQKGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIAL 608
Query: 585 --SVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKF 642
S++ Q P + P L+ L + CG+DN+C +L+LE
Sbjct: 609 NFSLDPQAPVDSHGLR------PALHYQSKSRIEDKAQILLD-CGEDNICVPDLQLE--- 658
Query: 643 CTREGNQDKFSYLPIQKGVPELVLKDQKDIAL-EITVTNSPSNPRNPTKDGDDAHEAKLI 701
V +Q + L + N + +N + G A+EA+L
Sbjct: 659 ----------------------VFGEQNHVYLGDKNALNLTFHAQNVGEGG--AYEAELR 694
Query: 702 ATFPDTLTYSAY-RELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEV 760
T P YS R F A C+LGNP K +++ L + +
Sbjct: 695 VTAPPEAEYSGLVRHPGNFSSLSCDYFAVNQSRLLVCDLGNPMKAGASLWGGLRFTVPHL 754
Query: 761 --TFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYF--GGTVVG 816
T T D + L N ++ + V + ++++GV+KP V F
Sbjct: 755 RDTKKTIQFDFQI-LSKNLNNSQSDVVSFRLSVEAQAQVTLNGVSKPEAVLFPVSDWHPR 813
Query: 817 EQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGL 876
+Q K ED +G + + + +IN G +++ L + P+ + G+ LLY+ +V
Sbjct: 814 DQPQKEED-LGPAVHHVYELINQGP--SSISQGVLELSCPQALE-GQQLLYVTRVTG--- 866
Query: 877 EKVTCEPQKEIN----SLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNV 932
+ C IN L+ S + ++KRE + A Q L C
Sbjct: 867 --LNCTTNHPINPKGLELDPEGSLHHQQKREAPSRSS---------ASSGPQILKCP-EA 914
Query: 933 NCVNIRCPLRGLDSKAS--LILRSRLWNSTFLE-EYSKLNYLDILMRAFIDVTAAAENIR 989
C +RC L L + S L L R+W TFL+ E+ + + + + +
Sbjct: 915 ECFRLRCELGPLHQQESQSLQLHFRVWAKTFLQREHQPFSLQCEAVYKALKMPYRILPRQ 974
Query: 990 LPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNKKDH 1049
LP QV V +K Y GVP WII++AIL G+L+L LL++IL+K GFFKR+
Sbjct: 975 LPQKERQVATAVQWTKAEGSY-GVPLWIIILAILFGLLLLGLLIYILYKLGFFKRSLP-- 1031
Query: 1050 YDATYHKAEIHAQPSDKERLTSDA 1073
Y KA++ K TSDA
Sbjct: 1032 YGTAMEKAQL------KPPATSDA 1049
>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
Length = 1032
Score = 286 bits (731), Expect = 9e-77
Identities = 282/1086 (25%), Positives = 473/1086 (43%), Gaps = 129/1086 (11%)
Query: 2 AAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRL 61
AA + +L L G+ + G +N+DT ++ + G +LFG+S+ +H R
Sbjct: 14 AAVRETVMLLLCLGVPT--GRPYNVDT--ESALLYQGPHNTLFGYSVVLH---SHGANRW 66
Query: 62 LLVGAPRAEALPLQRANRTGGLYSCDITARGP---CTRIEFDN-DADPTS----ESKEDQ 113
LLVGAP A L G +Y C I + P C +++ + + +P E +++Q
Sbjct: 67 LLVGAPTANWLANASVINPGAIYRCRI-GKNPGQTCEQLQLGSPNGEPCGKTCLEERDNQ 125
Query: 114 WMGVTVQSQ-GPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDW 172
W+GVT+ Q G G +VTC HR++ ++ K E++ G CY + +LR E
Sbjct: 126 WLGVTLSRQPGENGSIVTCGHRWKNIFYI--KNENKLPTGGCYGVPPDLRTELSKRIAP- 182
Query: 173 SFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIF 232
+ D + E F SCQ G+++ +TKD IV GAPG+ W G + V + +
Sbjct: 183 CYQDYVKKFGENFASCQAGISSFYTKDL--IVMGAPGSSYWTGSLFVYNITTNKYKAFLD 240
Query: 233 EDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLL 292
+ + G SYLG+S+ +G S+ V GAP+ G +
Sbjct: 241 KQNQVKFG---------------SYLGYSVGAGH-FRSQHTTEVVGGAPQHEQIGKAYIF 284
Query: 293 KRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVY 352
D K ++L H G+ L S FG V VDLN DG+ D+++GAP E G V+
Sbjct: 285 SIDEKELNIL--HEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIREE--GRVF 340
Query: 353 VYMNQ-QGRWNNVKPIRLNGTKD--SMFGIAVKNIGDINQDGYPDIAVGAPYDD--LGKV 407
VY+N G N L G+ + FG ++ N+GDI+ DG+ D+A+GAP +D G +
Sbjct: 341 VYINSGSGAVMNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAI 400
Query: 408 FIYHGSANGINTKPTQVLKGIS-----PYFGYSIAGNMDLDRNSYPDVAVGSL-SDSVTI 461
+IY+G A+GI++ +Q ++G+ FG SI+G +D D N Y DVAVG+ SDS +
Sbjct: 401 YIYNGRADGISSTFSQRIEGLQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVL 460
Query: 462 FRSRPVINIQKTITVTPNRIDLRQKTAC---GAPSGICLQVKSCFEYTANPAG------Y 512
R+RPV+ + +++ P ++ R K C G PS +C+ + CF Y Y
Sbjct: 461 LRTRPVVIVDASLS-HPESVN-RTKFDCVENGWPS-VCIDLTLCFSYKGKEVPGYIVLFY 517
Query: 513 NPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDN 572
N S+ + RK+ R F + G+ T + + ++ C +++ +
Sbjct: 518 NMSLDV---------NRKAESPPRFYFSSNGTSDVITGSIQVS-SREANCRTHQAFMRKD 567
Query: 573 IRDKLRPIPITASVEI-QEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNV 631
+RD L PI I A+ + S+R P + PIL + K C +N
Sbjct: 568 VRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN- 626
Query: 632 CNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKD 691
C+++L++ K +L + L + K + L +++ N+
Sbjct: 627 CSADLQV----------SAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNA---------- 666
Query: 692 GDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGS--QADCELGNPF---KRN 746
GDDA+E L P L + EL EKQ++C N Q DC +G +
Sbjct: 667 GDDAYETTLHVKLPVGLYFIKILELE---EKQINCEVTDNSGVVQLDCSIGYIYVDHLSR 723
Query: 747 SNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNL--APITAKAKVVIELLLSVSGVAK 804
+++F L +S+ + + ++ E DNL + +T + E+ L+V G
Sbjct: 724 IDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVN 783
Query: 805 PSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKW 864
P+ +G E E + + F VIN G + ++ I P S
Sbjct: 784 PTSFVYGSNDENE----PETCMVEKMNLTFHVINTGNSMA--PNVSVEIMVPNSFSPQTD 837
Query: 865 LLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQ 924
L+ + + E + + +L +S K + D R
Sbjct: 838 KLFNILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKR----------- 886
Query: 925 TLNC-SVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRA--FIDV 981
L C + +C+N C ++S + +L + E + + L +RA F +
Sbjct: 887 LLYCIKADPHCLNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEP 946
Query: 982 TAAAENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGF 1041
+ V + + +Y + II ++L G+++L L+ +++WK GF
Sbjct: 947 NPRVIELNKDENVAHVLLEGLHHQRPKRYFTIV--IISSSLLLGLIVLLLISYVMWKAGF 1004
Query: 1042 FKRNKK 1047
FKR K
Sbjct: 1005 FKRQYK 1010
>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
Length = 1039
Score = 236 bits (602), Expect = 9e-62
Identities = 271/1072 (25%), Positives = 469/1072 (43%), Gaps = 150/1072 (13%)
Query: 38 GDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGLYSCDITARG-PCTR 96
G GS FGFSL H + ++VGAPR P Q TGG++ C A G C
Sbjct: 44 GPNGSQFGFSLDFH--KDSHGRVAIVVGAPRTLG-PSQE--ETGGVFLCPWRAEGGQCPS 98
Query: 97 IEFD------NDADPTSES-KEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRD 149
+ FD N T ++ K Q +G +V S +V CA T++ +
Sbjct: 99 LLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSD--VIVACAPWQHWNVLEKTEEAEKT 156
Query: 150 IFGRCYVLSQNLRIEDDMDGGDWSFCDG----RLRGHEKFG----SCQQGVAATFTKDFH 201
G C++ + ++S C G R+ F C+ G ++ T+
Sbjct: 157 PVGSCFLAQP-----ESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGE 211
Query: 202 YIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGP--YEVGGETEHDESLVPVPANSYLG 259
+V GAPG Y + G++ + F + + G + V ++ +S P + Y G
Sbjct: 212 -LVLGAPGGYYFLGLLAQAPVADIF---SSYRPGILLWHVSSQSLSFDSSNPEYFDGYWG 267
Query: 260 FSLDSGKGIVSKDEITFVSGAPRANHS-GAVVLLKRDMKSAHLLPEHIFDGEGLASSFGY 318
+S+ G+ + +V GAP + + GAV +L + H L GE +AS FG+
Sbjct: 268 YSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLR-----GEQMASYFGH 322
Query: 319 DVAVVDLNKDGWQDIVIGAPQYF----DRDGEVGGAVYVYMNQQGRWNNVKP-IRLNGTK 373
VAV D+N DG D+++GAP Y DR G VY+++ +G P + L GT+
Sbjct: 323 SVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQ 382
Query: 374 -DSMFGIAVKNIGDINQDGYPDIAVGAPY---DDLGKVFIYHGSANGINTKPTQVLKGIS 429
FG A+ +GD+++DGY DIAV APY G+V ++ G + G+ ++P+QVL
Sbjct: 383 LYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPF 442
Query: 430 PY---FGYSIAGNMDLDRNSYPDVAVGSL-SDSVTIFRSRPVINIQKTITVTPNRIDLRQ 485
P FG+S+ G +D+D N YPD+ VG+ ++ V ++R++PV+ + V + +
Sbjct: 443 PTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVK 502
Query: 486 KTACGAPSG----ICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRN 541
+C P C ++ C T G+N + E + +R+K RV
Sbjct: 503 --SCVLPQTKTPVSCFNIQMCVGAT----GHNIPQKLSLNAELQLDRQKPRQGRRVLLLG 556
Query: 542 QGSEPKYTQELTLKRQKQKVCMEETLWLQD--NIRDKLRPIPITASVEIQEPSSRRRVNS 599
+ T L L + +C +L+D + RDKL PI ++ +V + +
Sbjct: 557 S-QQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEA----GM 611
Query: 600 LPEVLPILNSDEPKTAHIDVHFLKE-----GCGDDNVCNSNLKLEYKFCTREGNQDKFSY 654
P V+ H D H ++ CG+D+VC L+L
Sbjct: 612 APAVV----------LHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVT----------- 650
Query: 655 LPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYS-AY 713
G P LV D + L++ N +G+ A+EA+L P Y A
Sbjct: 651 -----GSPLLVGADNV-LELQMDAAN----------EGEGAYEAELAVHLPQGAHYMRAL 694
Query: 714 RELRAFPEKQLSCVANQNGSQAD-CELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLK 772
+ F E+ + +N ++ CELGNP K+N+ + +++S + + L+
Sbjct: 695 SNVEGF-ERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQ 753
Query: 773 LETTSNQD-NLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIE 831
+ + ++Q+ N + V E + + G + P+ + GE+ S D G +E
Sbjct: 754 IRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEE-GEREQNSLDSWGPKVE 812
Query: 832 YEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLN 891
+ + + N G N L+I P + S LLY++ ++ +G + C PQ +N L
Sbjct: 813 HTYELHNNGPGTVN--GLHLSIHLPGQ-SQPSDLLYILDIQPQG--GLQCFPQPPVNPLK 867
Query: 892 LT------------ESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRC 939
+ +H+ R +R+I + + + + ++C + C ++C
Sbjct: 868 VDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRL-----QDPVLVSCD-SAPCTVVQC 921
Query: 940 PLRGL--DSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTA---AAENIRLPNAG 994
L+ + +A + + + LW + + L+ + A+ +V++ A + LP
Sbjct: 922 DLQEMARGQRAMVTVLAFLWLPSLYQR--PLDQFVLQSHAWFNVSSLPYAVPPLSLPRGE 979
Query: 995 TQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNK 1046
QV + + + +P W +LV +L G+L+L +LV +WK GFFKRN+
Sbjct: 980 AQVWTQLLRA---LEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNR 1028
>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
Length = 1179
Score = 218 bits (554), Expect = 3e-56
Identities = 213/898 (23%), Positives = 389/898 (43%), Gaps = 141/898 (15%)
Query: 189 QQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDES 248
Q G +A +++D +++ GA G Y+W G V +++ + N + V +++
Sbjct: 379 QTGFSAHYSQD--WVMLGAVGAYDWNGTVVMQKASQIIIPRNT----TFNVESTKKNE-- 430
Query: 249 LVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFD 308
P SYLG++++S S ++ +++G PR NH+G V++ + + + +L
Sbjct: 431 ----PLASYLGYTVNSATA--SSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKIL--QTLS 482
Query: 309 GEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYMNQQGRWN---NV 364
GE + S FG + D++KD DI+ +GAP Y + E G VYVY Q R+ ++
Sbjct: 483 GEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSL 542
Query: 365 KPIRL----------------NGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDL--GK 406
+PI+ N + FG A+ + D+N DG+ DI +GAP +D G
Sbjct: 543 EPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGA 602
Query: 407 VFIYHGSANGINTKPTQVLKG-----ISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTI 461
V+IYHGS I + Q + +FG SI G MDL+ + DV +G L + +
Sbjct: 603 VYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAA-L 661
Query: 462 FRSRPVINIQKTITVTPNRIDLRQKTA-CGAPSGICLQVKSCFEY---TANPAGYNPSIS 517
F SR V ++ T+ PN++++++K +C+ CF+ + Y +
Sbjct: 662 FWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEADLQ 721
Query: 518 IVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKL 577
TL++ ++ +S S E K + +T+++ + C + + ++ D D
Sbjct: 722 YRVTLDSLRQISRSFFSGT-------QERKVQRNITVRKSE---CTKHSFYMLDK-HDFQ 770
Query: 578 RPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLK 637
+ IT + +P + P+L+ P + H + F K+ CG+ C S+L
Sbjct: 771 DSVRITLDFNLTDPENG----------PVLDDSLPNSVHEYIPFAKD-CGNKEKCISDLS 819
Query: 638 LEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKD-IALEITVTNSPSNPRNPTKDGDDAH 696
L ++ L+++ Q D + +TV N+ D A+
Sbjct: 820 LHVATTEKD----------------LLIVRSQNDKFNVSLTVKNTK----------DSAY 853
Query: 697 EAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLS 756
+ I + L +S ++ + SC +N N C++G PF R + + +L
Sbjct: 854 NTRTIVHYSPNLVFSGIEAIQ-----KDSCESNHN---ITCKVGYPFLRRGEMVTFKILF 905
Query: 757 TTEVTFDTPDLDINLKLETTSNQ------DNLAPITAKAKVVIELLLSVSGVAKPSQVYF 810
++ ++ I L + S + DN+ I+ K + L S +
Sbjct: 906 QFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAA 965
Query: 811 GGTVVGEQAMKSEDEVGSLIEYEFRVINLGK-PLTNLGTATLNIQWPKEISNGKWLLYLV 869
TV + + S +++G+ I + + G P+ L L+I +P SNG +LY
Sbjct: 966 NETV--PEVINSTEDIGNEINIFYLIRKSGSFPMPEL---KLSISFPNMTSNGYPVLYPT 1020
Query: 870 KVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCS 929
+ S E C P + ++ NS KK + + K+ T+ C+
Sbjct: 1021 GLSSS--ENANCRPHIFEDPFSI----NSGKKMTTSTDHLKRGTILDCNT-CKFATITCN 1073
Query: 930 VNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIR 989
+ + ++ SLIL W TF++ Y + L++ +R + A+ +
Sbjct: 1074 LTSSDIS--------QVNVSLIL----WKPTFIKSY--FSSLNLTIRGELRSENASLVLS 1119
Query: 990 LPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNKK 1047
N ++ + + + VP W+IL++ AG+L+L LL+ LWK GFFKR K
Sbjct: 1120 SSNQKRELAIQISKDGLPGR---VPLWVILLSAFAGLLLLMLLILALWKIGFFKRPLK 1174
Score = 42.0 bits (97), Expect = 0.003
Identities = 37/125 (29%), Positives = 62/125 (49%), Gaps = 16/125 (12%)
Query: 19 RLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRAN 78
R +FN+D + N + G +FG+++ Q + E+ + +L+G+P L Q N
Sbjct: 24 RCCVSFNVDVK--NSMTFSGPVEDMFGYTVQ---QYENEEGKWVLIGSP----LVGQPKN 74
Query: 79 RTGGLYSCDITARG---PCTRIEFD-NDADP-TSESKEDQWMGVTVQSQGPGGKVVTCAH 133
RTG +Y C + RG PC +++ N + P +E KE+ G T+ + P G + C
Sbjct: 75 RTGDVYKCPV-GRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVT-NPNGGFLACGP 132
Query: 134 RYEKR 138
Y R
Sbjct: 133 LYAYR 137
>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
Length = 1181
Score = 204 bits (519), Expect = 4e-52
Identities = 218/904 (24%), Positives = 393/904 (43%), Gaps = 142/904 (15%)
Query: 176 DGRLRGHEKFGS--CQQGVAATFTKDFHYIVFGAPGTYNWKG-IVRVEQKNNTFFDMNIF 232
+G ++G + F Q G +A ++ ++ GA G + W G IV+ + F F
Sbjct: 365 EGTVQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAF 424
Query: 233 EDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEIT-FVSGAPRANHSGAVVL 291
D+ L +SYLG+S+ + +S E T FV+GAPRAN++G +VL
Sbjct: 425 -------------DQILQDRNHSSYLGYSVAA----ISTGESTHFVAGAPRANYTGQIVL 467
Query: 292 LKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGA 350
+ ++ ++ G+ + S FG + VD++KD D++ +GAP Y + G
Sbjct: 468 YSVN-ENGNITVIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGR 526
Query: 351 VYVYMNQQGRWNNVKPIR-LNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDL--GKV 407
VY++ ++G + + G +++ FG A+ + DIN DG+ D+ VG+P ++ G V
Sbjct: 527 VYLFTIKEGILGQHQFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAV 586
Query: 408 FIYHGSANGINTKPTQVLKGIS-------PYFGYSIAGNMDLDRNSYPDVAVGSLSDSVT 460
+IY+G I TK +Q + G YFG S+ G DL+ +S DV++G+ V
Sbjct: 587 YIYNGHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQ 646
Query: 461 IFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVG 520
++ S+ + ++ + TP +I L K A + +K CF P N ++IV
Sbjct: 647 LW-SQSIADVAIEASFTPEKITLVNKNAQ-------IILKLCFSAKFRPTKQNNQVAIVY 698
Query: 521 TLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPI 580
+ + + S ++SR F+ + Q+ + Q Q C E +++Q+ D + +
Sbjct: 699 NITLDADGFSSRVTSRGLFKENNE--RCLQKNMVVNQAQS-CPEHIIYIQEP-SDVVNSL 754
Query: 581 PITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEY 640
+ + ++ P + + + E + + + F K+ CG+D +C S+L L+
Sbjct: 755 DLRVDISLENPGTSPALEAYSETAKVFS----------IPFHKD-CGEDGLCISDLVLDV 803
Query: 641 KFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKL 700
+ +P + P +V K + +T+ N + A+ +
Sbjct: 804 R------------QIPAAQEQPFIVSNQNKRLTFSVTLKNKR----------ESAYNTGI 841
Query: 701 IATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNP-FKRNSNVTFYLVLSTTE 759
+ F + L ++++ +++C + C++G P KR VTF T
Sbjct: 842 VVDFSENLFFASFS--LPVDGTEVTCQVAASQKSVACDVGYPALKREQQVTF-----TIN 894
Query: 760 VTFDTPDLDINLKLE----TTSNQDNLAPITAKAKVVI----ELLLSVSGVAKPSQVYFG 811
F+ +L L + S ++N A K+ + E+ L+ S ++
Sbjct: 895 FDFNLQNLQNQASLSFQALSESQEENKADNLVNLKIPLLYDAEIHLTRSTNINFYEISSD 954
Query: 812 GTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKV 871
G V + S ++VG + +V P++ AT+ I P+ L+YL V
Sbjct: 955 GNV--PSIVHSFEDVGPKFIFSLKVTTGSVPVS---MATVIIHIPQYTKEKNPLMYLTGV 1009
Query: 872 ESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVN 931
++ ++C +IN L + ++ +S F R + LNC
Sbjct: 1010 QTDKAGDISCNA--DINPLKIGQTSSSVS--------------FKSENFRHTKELNCRT- 1052
Query: 932 VNCVNIRCPLRGLDSKASLILR--SRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIR 989
+C N+ C L+ + K + +R+WN TF + + +TAAAE I
Sbjct: 1053 ASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFASSTFQT----------VQLTAAAE-IN 1101
Query: 990 LPNAGTQVRVTVFPSKTVA---------QYSGVPWWIILVAILAGILMLALLVFILWKCG 1040
N + V TV + + VP +I+ +I+AGIL+L LV ILWK G
Sbjct: 1102 TYNP----EIYVIEDNTVTIPLMIMKPDEKAEVPTGVIIGSIIAGILLLLALVAILWKLG 1157
Query: 1041 FFKR 1044
FFKR
Sbjct: 1158 FFKR 1161
>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
Length = 1167
Score = 188 bits (477), Expect = 3e-47
Identities = 226/884 (25%), Positives = 369/884 (41%), Gaps = 131/884 (14%)
Query: 203 IVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYLGFSL 262
I+FG G Y+W G V + + F P + E E +L A YLG+S+
Sbjct: 386 ILFGMVGAYDWGGSVLWLEGGHRLF--------PPRMALEDEFPPALQNHAA--YLGYSV 435
Query: 263 DSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAV 322
S ++ F+SGAPR H G V+ + A + + + GE + S FG ++
Sbjct: 436 SSM--LLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSL-QGEQIGSYFGSELCP 492
Query: 323 VDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYM-NQQGRWNNVKPIRLNGTKDSMFGIA 380
+D ++DG D++ + AP + + G VYVY+ QQ ++ +D+ FG A
Sbjct: 493 LDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQPEPPQDARFGFA 552
Query: 381 VKNIGDINQDGYPDIAVGAPYDD--LGKVFIYHGSANGINTKPTQVLKGIS-----PYFG 433
+ + D+NQDG+ D+AVGAP +D G +++YHG+ +G+ P Q + S YFG
Sbjct: 553 MGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYFG 612
Query: 434 YSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTA-CGAP 492
S+ G +DLD + DVAVG+ ++ + SRP++++ ++ VTP I + Q+
Sbjct: 613 RSVDGRLDLDGDDLVDVAVGAQGAAI-LLSSRPIVHLTPSLEVTPQAISVVQRDCRRRGQ 671
Query: 493 SGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQEL 552
+CL CF+ T+ G A + +G + Q P+
Sbjct: 672 EAVCLTAALCFQVTSRTPG-RWDHQFYMRFTASLDEWTAGARAAFDGSGQRLSPR----- 725
Query: 553 TLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEP 612
L+ V E+ + + D LRP+ +T + + + P+LN P
Sbjct: 726 RLRLSVGNVTCEQLHFHVLDTSDYLRPVALTVTFALDNTTKPG---------PVLNEGSP 776
Query: 613 KTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDI 672
+ V F K+ CG DN C ++L L+ R + P +V ++ +
Sbjct: 777 TSIQKLVPFSKD-CGPDNECVTDLVLQVNMDIRGSRK-----------APFVVRGGRRKV 824
Query: 673 ALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNG 732
+ T+ N N A+ L F L ++ R P K + C A
Sbjct: 825 LVSTTLENRKEN----------AYNTSLSLIFSRNLHLASLTPQRESPIK-VECAAPSAH 873
Query: 733 SQADCELGNP-FKRNSNVTFYLVLSTTEVTFDTPDL--DINLKLETTSN--------QDN 781
++ C +G+P F+ + VTF L E F L + +KL +S+ QDN
Sbjct: 874 ARL-CSVGHPVFQTGAKVTFLL-----EFEFSCSSLLSQVFVKLTASSDSLERNGTLQDN 927
Query: 782 LAPITAKAKVVIELLLSVSGVAKPSQVYFGGTV-VGEQAMKSEDEVGSLIEYEFRVINLG 840
A +A + LL S +V+ GT+ VG G + RV NLG
Sbjct: 928 TAQTSAYIQYEPHLLFSSESTLHRYEVHPYGTLPVGP---------GPEFKTTLRVQNLG 978
Query: 841 KPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRK 900
+ + ++ P G + L L +V + +C Q NLTE
Sbjct: 979 CYV--VSGLIISALLPAVAHGGNYFLSLSQVIT---NNASCIVQ------NLTEPPGPPV 1027
Query: 901 KREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPL----RGLDSKASLILRSRL 956
E + NR LN S N C +RC L +G + L+ RL
Sbjct: 1028 HPEELQ---HTNR------------LNGS-NTQCQVVRCHLGQLAKGTEVSVGLL---RL 1068
Query: 957 WNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAG--TQVRVTVFPSKTVAQYSGVP 1014
++ F +K L + + F T ++L A ++ + V ++ + +
Sbjct: 1069 VHNEFFRR-AKFKSLTV-VSTFELGTEEGSVLQLTEASRWSESLLEVVQTRPIL----IS 1122
Query: 1015 WWIILVAILAGILMLALLVFILWKCGFFKRNKKDHYDATYHKAE 1058
WI++ ++L G+L+LALLVF LWK GFF K + K E
Sbjct: 1123 LWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPEEEKREEKLE 1166
>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
Length = 1188
Score = 181 bits (460), Expect = 3e-45
Identities = 226/927 (24%), Positives = 388/927 (41%), Gaps = 132/927 (14%)
Query: 163 IEDDMDG-GDWSFC-DGRLRGHEKFG--SCQQGVAATFTKDFHYIVFGAPGTYNWKGIVR 218
++D +D GD F +G + FG Q G ++ +D ++ GA G Y+W G V
Sbjct: 338 LKDIVDALGDRIFSLEGTNKNETSFGLEMSQTGFSSHVVEDG--VLLGAVGAYDWNGAVL 395
Query: 219 VEQKNNTFFDM--NIFEDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITF 276
E + + ++ P E+ +YLG+++ S + S+ +
Sbjct: 396 KETSAGKVIPLRESYLKEFPEELKNH------------GAYLGYTVTSV--VSSRQGRVY 441
Query: 277 VSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIV-I 335
V+GAPR NH+G V+L + L G+ + S FG ++ VD++ DG D++ +
Sbjct: 442 VAGAPRFNHTGKVILFTMH-NNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGVTDVLLV 500
Query: 336 GAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGT-KDS------MFGIAVKNIGDIN 388
GAP YF+ +G G VYVY +Q + NGT KDS FG ++ ++ D+N
Sbjct: 501 GAPMYFN-EGRERGKVYVYELRQNLFV------YNGTLKDSHSYQNARFGSSIASVRDLN 553
Query: 389 QDGYPDIAVGAPYDD--LGKVFIYHGSANGINTKPTQVLKGIS-----PYFGYSIAGNMD 441
QD Y D+ VGAP +D G ++I+HG I P Q + YFG SI G +D
Sbjct: 554 QDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATGLQYFGCSIHGQLD 613
Query: 442 LDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDL-RQKTACGAPSGICLQVK 500
L+ + D+AVG+L ++V ++ SRPV+ I ++ P++I++ + CL
Sbjct: 614 LNEDGLIDLAVGALGNAVILW-SRPVVQINASLHFEPSKINIFHRDCKRSGRDATCLAAF 672
Query: 501 SCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQK 560
CF + + + ERR + R G ++T L Q+
Sbjct: 673 LCFTPIFLAPHFQTTTVGIRYNATMDERR---YTPRAHLDEGGD--RFTNRAVLLSSGQE 727
Query: 561 VCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVH 620
+C + D D ++P+ + +++P P+L+ P T + V
Sbjct: 728 LCERINFHVLDT-ADYVKPVTFSVEYSLEDPDHG----------PMLDDGWPTTLRVSVP 776
Query: 621 FLKEGCGDDNVC--------NSNLKLEYKFC---TREGNQDKFSYLPIQKGVPELVLKDQ 669
F GC +D C S+L ++C R+ QD +Y ++ +
Sbjct: 777 FW-NGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTR 835
Query: 670 KDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVAN 729
+ +A+E T+ N G++A+ L + L +++ + + + + CV
Sbjct: 836 QRVAVEATLENR----------GENAYSTVLNISQSANLQFASLIQ-KEDSDGSIECVNE 884
Query: 730 QNGSQAD-CELGNPFKR-NSNVTFYLVLSTTEVTFDTPDLDINLKLETTSN------QDN 781
+ Q C + PF R + V F L ++ F L+I L + SN +DN
Sbjct: 885 ERRLQKQVCNVSYPFFRAKAKVAFRLDFEFSKSIF-LHHLEIELAAGSDSNERDSTKEDN 943
Query: 782 LAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGK 841
+AP+ K ++L + S + V +++ D +G FR+ NLG
Sbjct: 944 VAPLRFHLKYEADVLFTRSSSLSHYE------VKPNSSLERYDGIGPPFSCIFRIQNLG- 996
Query: 842 PLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSL-NLTESHNSRK 900
L + + I P +G LL L + +T E N N TE +
Sbjct: 997 -LFPIHGMMMKITIPIATRSGNRLLKL-------RDFLTDEANTSCNIWGNSTEYRPTPV 1048
Query: 901 KREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNST 960
+ ++ R+ LN S N + V+I C +R + ++ + L +
Sbjct: 1049 EEDL----------------RRAPQLNHS-NSDVVSINCNIRLVPNQE---INFHLLGNL 1088
Query: 961 FLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILV 1020
+L L Y + + + + + R VF + VP WII+
Sbjct: 1089 WLRSLKALKYKSMKIMVNAALQRQFHSPFIFREEDPSRQIVFEISKQEDWQ-VPIWIIVG 1147
Query: 1021 AILAGILMLALLVFILWKCGFFKRNKK 1047
+ L G+L+LALLV LWK GFF+ ++
Sbjct: 1148 STLGGLLLLALLVLALWKLGFFRSARR 1174
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 157 bits (396), Expect = 7e-38
Identities = 216/903 (23%), Positives = 387/903 (42%), Gaps = 157/903 (17%)
Query: 189 QQGVAATFTKDFHYIVFGAPGTYNWKG--IVRVEQKNNTFFDMNIFEDGPYEVGGETEHD 246
Q+G +A T + + G+Y+W G + ++ +TF +M T D
Sbjct: 352 QEGFSAAITSNGPLL--STVGSYDWAGGVFLYTSKEKSTFINM-------------TRVD 396
Query: 247 ESLVPVPANSYLGFSLDSGKGIVSKDEI-TFVSGAPRANHSGAVVLLKRDM----KSAHL 301
+ ++YLG++ I+ ++ + + V GAPR H G V + +++ +A++
Sbjct: 397 SDM----NDAYLGYAA----AIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV 448
Query: 302 LPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVY---MNQ 357
G + + FG + VD++ +G D+V IGAP Y+++ GG V V Q
Sbjct: 449 ------KGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGQ 500
Query: 358 QGRWN-NVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAP--YDDLGKVFIYHG-S 413
+ RW + G FG A+ +GD+N D D+A+GAP D+ G V+++HG S
Sbjct: 501 RARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTS 560
Query: 414 ANGINTKPTQVLKG--ISP---YFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVI 468
+GI+ +Q + G +SP YFG S++G DL + D+ VG+ V + RS+PV+
Sbjct: 561 GSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGA-QGHVLLLRSQPVL 619
Query: 469 NIQKTITVTPNRI-----DLRQKTACGAPSG---ICLQVKSCFEYTANPAGYNPSISIVG 520
++ + P + + + G +G +CL V+ ++
Sbjct: 620 RVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDL 679
Query: 521 TLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPI 580
L++ + ++ + + S + TQ L L + C L L + I D + PI
Sbjct: 680 ALDSGRPHSRAVFNE-----TKNSTRRQTQVLGLTQ----TCETLKLQLPNCIEDPVSPI 730
Query: 581 PITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEY 640
+ + + +++ + P+L D + F K CG+DN+C +L + +
Sbjct: 731 VLRLNFSLVGTP----LSAFGNLRPVLAEDAQRLFTALFPFEKN-CGNDNICQDDLSITF 785
Query: 641 KFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKL 700
F + + LV+ ++ + +TV N DG+D++ ++
Sbjct: 786 SFMSLDC----------------LVVGGPREFNVTVTVRN----------DGEDSYRTQV 819
Query: 701 IATFPDTLTY---SAYRELRAFPEKQLSCVANQNGS------QADCELGNP-FKRNSNVT 750
FP L+Y S + R+ +L+C + + C + +P F NS VT
Sbjct: 820 TFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVT 879
Query: 751 FYLVLSTTEVTFDTPD---LDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQ 807
F +TFD L L L+ +N P T K + +EL + +
Sbjct: 880 F-------NITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKYA------- 925
Query: 808 VYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLY 867
VY VV + ++ + E RV+ ++NLG +L I L++
Sbjct: 926 VYM---VVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPIS----------LVF 972
Query: 868 LVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLN 927
LV V + V + + S NL+ + + T++++ + F L RK +N
Sbjct: 973 LVPVRLN--QTVIWDRPQVTFSENLSSTCH-------TKERLPSHSDF-LAELRKAPVVN 1022
Query: 928 CSVNVNCVNIRC--PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAA 985
CS+ V C I+C P G+ + + L+ L +++ + N+L I+ A I +
Sbjct: 1023 CSIAV-CQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTAEILFNDSV 1079
Query: 986 ENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRN 1045
+ LP G VR +K P +I+ + + G+L+LAL+ L+K GFFKR
Sbjct: 1080 FTL-LPGQGAFVRSQT-ETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQ 1137
Query: 1046 KKD 1048
KD
Sbjct: 1138 YKD 1140
Score = 31.6 bits (70), Expect = 4.2
Identities = 35/139 (25%), Positives = 59/139 (42%), Gaps = 24/139 (17%)
Query: 24 FNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGL 83
FNLDT + + FG S+ QLQ ++VGAP+ + AN+ G L
Sbjct: 17 FNLDTEN---AMTFQENARGFGQSVV---QLQGSR---VVVGAPQE----IVAANQRGSL 63
Query: 84 YSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNT 143
Y CD + G C I + + S +G+++ + +++ C + T
Sbjct: 64 YQCDYST-GSCEPIRLQVPVEAVNMS-----LGLSLAATTSPPQLLACGPTVHQ-----T 112
Query: 144 KQESRDIFGRCYVLSQNLR 162
E+ + G C++ NLR
Sbjct: 113 CSENTYVKGLCFLFGSNLR 131
>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
Length = 1152
Score = 155 bits (393), Expect = 1e-37
Identities = 216/902 (23%), Positives = 387/902 (42%), Gaps = 156/902 (17%)
Query: 189 QQGVAATFTKDFHYIVFGAPGTYNWKG--IVRVEQKNNTFFDMNIFEDGPYEVGGETEHD 246
Q+G +A T + + G+Y+W G + ++ +TF +M T D
Sbjct: 352 QEGFSAAITSNGPLL--STVGSYDWAGGVFLYTSKEKSTFINM-------------TRVD 396
Query: 247 ESLVPVPANSYLGFSLDSGKGIVSKDEI-TFVSGAPRANHSGAVVLLKRDM----KSAHL 301
+ ++YLG++ I+ ++ + + V GAPR H G V + +++ +A++
Sbjct: 397 SDM----NDAYLGYAA----AIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV 448
Query: 302 LPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYMNQQGR 360
G + + FG + VD++ +G D+V IGAP Y+++ GG V V +GR
Sbjct: 449 ------KGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGR 500
Query: 361 WNNVKPIRLNGTKDS---MFGIAVKNIGDINQDGYPDIAVGAP--YDDLGKVFIYHG-SA 414
L G + FG A+ +GD+N D D+A+GAP D+ G V+++HG S
Sbjct: 501 ARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSG 560
Query: 415 NGINTKPTQVLKG--ISP---YFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVIN 469
+GI+ +Q + G +SP YFG S++G DL + D+ VG+ V + RS+PV+
Sbjct: 561 SGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGA-QGHVLLLRSQPVLR 619
Query: 470 IQKTITVTPNRI-----DLRQKTACGAPSG---ICLQVKSCFEYTANPAGYNPSISIVGT 521
++ + P + + + G +G +CL V+ ++
Sbjct: 620 VKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLA 679
Query: 522 LEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIP 581
L++ + ++ + + S + TQ L L + C L L + I D + PI
Sbjct: 680 LDSGRPHSRAVFNE-----TKNSTRRQTQVLGLTQ----TCETLKLQLPNCIEDPVSPIV 730
Query: 582 ITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYK 641
+ + + +++ + P+L D + F K CG+DN+C +L + +
Sbjct: 731 LRLNFSLVGTP----LSAFGNLRPVLAEDAQRLFTALFPFEKN-CGNDNICQDDLSITFS 785
Query: 642 FCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLI 701
F + + LV+ ++ + +TV N DG+D++ ++
Sbjct: 786 FMSLDC----------------LVVGGPREFNVTVTVRN----------DGEDSYRTQVT 819
Query: 702 ATFPDTLTY---SAYRELRAFPEKQLSCVANQNGS------QADCELGNP-FKRNSNVTF 751
FP L+Y S + R+ +L+C + + C + +P F NS VTF
Sbjct: 820 FFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTF 879
Query: 752 YLVLSTTEVTFDTPD---LDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQV 808
+TFD L L L+ +N P T K + +EL + + V
Sbjct: 880 -------NITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKYA-------V 925
Query: 809 YFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYL 868
Y VV + ++ + E RV+ ++NLG +L I L++L
Sbjct: 926 YM---VVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPIS----------LVFL 972
Query: 869 VKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNC 928
V V + V + + S NL+ + + T++++ + F L RK +NC
Sbjct: 973 VPVRLN--QTVIWDRPQVTFSENLSSTCH-------TKERLPSHSDF-LAELRKAPVVNC 1022
Query: 929 SVNVNCVNIRC--PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAE 986
S+ V C I+C P G+ + + L+ L +++ + N+L I+ A I +
Sbjct: 1023 SIAV-CQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTAEILFNDSVF 1079
Query: 987 NIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNK 1046
+ LP G VR +K P +I+ + + G+L+LAL+ L+K GFFKR
Sbjct: 1080 TL-LPGQGAFVRSQT-ETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQY 1137
Query: 1047 KD 1048
KD
Sbjct: 1138 KD 1139
Score = 31.6 bits (70), Expect = 4.2
Identities = 35/139 (25%), Positives = 59/139 (42%), Gaps = 24/139 (17%)
Query: 24 FNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGL 83
FNLDT + + FG S+ QLQ ++VGAP+ + AN+ G L
Sbjct: 17 FNLDTEN---AMTFQENARGFGQSVV---QLQGSR---VVVGAPQE----IVAANQRGSL 63
Query: 84 YSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNT 143
Y CD + G C I + + S +G+++ + +++ C + T
Sbjct: 64 YQCDYST-GSCEPIRLQVPVEAVNMS-----LGLSLAATTSPPQLLACGPTVHQ-----T 112
Query: 144 KQESRDIFGRCYVLSQNLR 162
E+ + G C++ NLR
Sbjct: 113 CSENTYVKGLCFLFGSNLR 131
>gi|148728188 integrin, alpha E precursor [Homo sapiens]
Length = 1179
Score = 148 bits (374), Expect = 2e-35
Identities = 147/617 (23%), Positives = 273/617 (44%), Gaps = 107/617 (17%)
Query: 199 DFHYIVFGAPGTYNWKG---IVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPAN 255
D ++ GA G ++W G + + F + E
Sbjct: 412 DERQVLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAA-------------QY 458
Query: 256 SYLGFSLDSGKGIVSKD-EITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLAS 314
SYLG+++ ++ K +++++GAPR H GAV L+++ + A LP + +GE + S
Sbjct: 459 SYLGYAV----AVLHKTCSLSYIAGAPRYKHHGAVFELQKEGREASFLP--VLEGEQMGS 512
Query: 315 SFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYM--NQQGRWNNVKPIRLN-G 371
FG ++ VD++ DG D ++ A ++ GE G VYVY Q G ++ + + + G
Sbjct: 513 YFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEG-RVYVYRLSEQDGSFSLARILSGHPG 571
Query: 372 TKDSMFGIAVKNIGDINQDGYPDIAVGAPYD--------DLGKVFIYHGSANGINTKPTQ 423
++ FG A+ +GD++QD D+A+GAP + G V+IY+G +G++ P+Q
Sbjct: 572 FTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSASPSQ 631
Query: 424 VLKG--ISP---YFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTP 478
++ ++P YFG S+AG D+ + D+ VG+L +V +FRSRPV+ ++ ++ TP
Sbjct: 632 RIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQAV-VFRSRPVVRLKVSMAFTP 690
Query: 479 NRIDLRQKTACGAPSGICLQVKSCFEY----TANPAGYNPS-ISIVGTLEAEKERRKSGL 533
+ + + +G+ + V+ CFE TA+ +G + ++ ++ K+RR+
Sbjct: 691 SALPI-------GFNGV-VNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQC 742
Query: 534 SSRVQ----FRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQ 589
S R S + ++L L + ++C E D + S ++Q
Sbjct: 743 SDVRSCLGCLREWSSGSQLCEDLLLMPTEGELCEE----------DCFSNASVKVSYQLQ 792
Query: 590 EPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQ 649
P + P+ PIL+ A + + + C + L FC E
Sbjct: 793 TPEGQ---TDHPQ--PILDRYTEPFAIFQLPY-------EKACKNKL-----FCVAE--- 832
Query: 650 DKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLT 709
L ELV+ K++ L I +TNS G+D++ + +P L
Sbjct: 833 ---LQLATTVSQQELVVGLTKELTLNINLTNS----------GEDSYMTSMALNYPRNL- 878
Query: 710 YSAYRELRAFPEKQLSCVANQNGSQA---DCELGNPFKRNSNVTFYLVLSTTEVTFDTPD 766
+ ++ P + C Q + +C +G+P + S+ +V E F
Sbjct: 879 --QLKRMQKPPSPNIQCDDPQPVASVLIMNCRIGHPVLKRSSAHVSVVWQLEENAFPNRT 936
Query: 767 LDINLKLETTSNQDNLA 783
DI + + ++ + +LA
Sbjct: 937 ADITVTVTNSNERRSLA 953
Score = 38.1 bits (87), Expect = 0.045
Identities = 22/77 (28%), Positives = 42/77 (54%), Gaps = 5/77 (6%)
Query: 986 ENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRN 1045
E + N T++ V + +Y +P II+ + G+L+L +++ IL+KCGFFKR
Sbjct: 1101 EGLNAENHRTKITVVFLKDE---KYHSLP--IIIKGSVGGLLVLIVILVILFKCGFFKRK 1155
Query: 1046 KKDHYDATYHKAEIHAQ 1062
+ + KA++ ++
Sbjct: 1156 YQQLNLESIRKAQLKSE 1172
>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
Length = 1086
Score = 142 bits (357), Expect = 2e-33
Identities = 156/643 (24%), Positives = 276/643 (42%), Gaps = 105/643 (16%)
Query: 191 GVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLV 250
G++A ++ + V GA G +W G F D+ +G +E L
Sbjct: 270 GISADLSRG--HAVVGAVGAKDWAG---------GFLDLKADLQDDTFIG-----NEPLT 313
Query: 251 PVPANSYLGFSLDSGKGIVSKDEITFV-SGAPRANHSGAVVLLKRDMKSAHLLPEHIFDG 309
P YLG+++ + S+ + + + SGAPR H G V+L + H G
Sbjct: 314 PEVRAGYLGYTVT---WLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHG 370
Query: 310 EGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIR 368
+ S FG ++ VD+++DG +++ IGAP ++ + GG V++Y +Q + V ++
Sbjct: 371 TQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGE--QRGGRVFIYQRRQLGFEEVSELQ 428
Query: 369 LN-GTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKP------ 421
+ G FG A+ + DIN DG D+AVGAP ++ G V+I++G G++ +P
Sbjct: 429 GDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEG 488
Query: 422 TQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRI 481
TQVL GI +FG SI G DL+ + DVAVG+ S + + SRPV+++ ++ +P I
Sbjct: 489 TQVLSGIQ-WFGRSIHGVKDLEGDGLADVAVGAESQMI-VLSSRPVVDMVTLMSFSPAEI 546
Query: 482 DLRQ---------KTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSG 532
+ + K G IC Q+KS N + TL+ + R
Sbjct: 547 PVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVAN----LTYTLQLDGHRT--- 599
Query: 533 LSSRVQFRNQGSEPKYTQEL--TLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQE 590
R +G P EL + C + + ++D + PI ++ + + E
Sbjct: 600 -------RRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWE 652
Query: 591 ----PSSRRRVNSLPEVL-PILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTR 645
P +R +P +L P L+S+ + ++ CG+D C +NL++ +
Sbjct: 653 EEGTPRDQRAGKDIPPILRPSLHSETWEIP------FEKNCGEDKKCEANLRVSF----- 701
Query: 646 EGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFP 705
+ AL +T S S + + +DA+ +L FP
Sbjct: 702 ---------------------SPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFP 740
Query: 706 DTLTYSAYRELRAFPEKQLSCVANQNGSQ-----ADCELGNP-FKRNSNVTFYLVLST-- 757
L++ L+ + +SC S+ C + +P FK +V ++ +T
Sbjct: 741 PGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLV 800
Query: 758 TEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVS 800
D+ +L N+ T +N+D+ A +I +L ++
Sbjct: 801 NSSWGDSVELHANV---TCNNEDSDLLEDNSATTIIPILYPIN 840
Score = 36.2 bits (82), Expect = 0.17
Identities = 14/37 (37%), Positives = 27/37 (72%)
Query: 1016 WIILVAILAGILMLALLVFILWKCGFFKRNKKDHYDA 1052
++ +++ + G+L+L L+ +L+K GFFKRN K+ +A
Sbjct: 1007 YLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEA 1043
>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
Length = 1170
Score = 139 bits (349), Expect = 2e-32
Identities = 155/644 (24%), Positives = 275/644 (42%), Gaps = 106/644 (16%)
Query: 191 GVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLV 250
G++A ++ + V GA G +W G F D+ +G +E L
Sbjct: 353 GISADLSRG--HAVVGAVGAKDWAG---------GFLDLKADLQDDTFIG-----NEPLT 396
Query: 251 PVPANSYLGFSLDSGKGIVSKDEITFV-SGAPRANHSGAVVLLKRDMKSAHLLPEHIFDG 309
P YLG+++ + S+ + + + SGAPR H G V+L + H G
Sbjct: 397 PEVRAGYLGYTVT---WLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHG 453
Query: 310 EGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIR 368
+ S FG ++ VD+++DG +++ IGAP ++ + GG V++Y +Q + V ++
Sbjct: 454 TQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGE--QRGGRVFIYQRRQLGFEEVSELQ 511
Query: 369 LN-GTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKP------ 421
+ G FG A+ + DIN DG D+AVGAP ++ G V+I++G G++ +P
Sbjct: 512 GDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEG 571
Query: 422 TQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRI 481
TQVL GI +FG SI G DL+ + DVAVG+ S + + SRPV+++ ++ +P I
Sbjct: 572 TQVLSGIQ-WFGRSIHGVKDLEGDGLADVAVGAESQMI-VLSSRPVVDMVTLMSFSPAEI 629
Query: 482 DLRQ---------KTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSG 532
+ + K G IC Q+KS N + TL+ + R
Sbjct: 630 PVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVAN----LTYTLQLDGHRT--- 682
Query: 533 LSSRVQFRNQGSEPKYTQEL--TLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQE 590
R +G P EL + C + + ++D + PI ++ + + E
Sbjct: 683 -------RRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWE 735
Query: 591 P-----SSRRRVNSLPEVL-PILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCT 644
R + +P +L P L+S+ + ++ CG+D C +NL++ +
Sbjct: 736 EEGTPRDQRAQGKDIPPILRPSLHSETWEIP------FEKNCGEDKKCEANLRVSF---- 785
Query: 645 REGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATF 704
+ AL +T S S + + +DA+ +L F
Sbjct: 786 ----------------------SPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHF 823
Query: 705 PDTLTYSAYRELRAFPEKQLSCVANQNGSQ-----ADCELGNP-FKRNSNVTFYLVLST- 757
P L++ L+ + +SC S+ C + +P FK +V ++ +T
Sbjct: 824 PPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTL 883
Query: 758 -TEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVS 800
D+ +L N+ T +N+D+ A +I +L ++
Sbjct: 884 VNSSWGDSVELHANV---TCNNEDSDLLEDNSATTIIPILYPIN 924
Score = 36.2 bits (82), Expect = 0.17
Identities = 14/37 (37%), Positives = 27/37 (72%)
Query: 1016 WIILVAILAGILMLALLVFILWKCGFFKRNKKDHYDA 1052
++ +++ + G+L+L L+ +L+K GFFKRN K+ +A
Sbjct: 1091 YLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEA 1127
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 137 bits (346), Expect = 4e-32
Identities = 215/914 (23%), Positives = 378/914 (41%), Gaps = 181/914 (19%)
Query: 189 QQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDES 248
Q+G +A FT D V GA G++ W G + N + +N+ ++
Sbjct: 353 QEGFSAVFTPDGP--VLGAVGSFTWSGGAFLYPPNMSPTFINMSQENVDM---------- 400
Query: 249 LVPVPANSYLGFSLDSG--KGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHI 306
+SYLG+S + KG+ S V GAPR H+G V+ + + + E
Sbjct: 401 -----RDSYLGYSTELALWKGVQS-----LVLGAPRYQHTGKAVIFTQVSRQWRMKAE-- 448
Query: 307 FDGEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYMNQQGR---WN 362
G + S FG + VD++ DG D+V IGAP Y+++ GG V V +G W
Sbjct: 449 VTGTQIGSYFGASLCSVDVDSDGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGWRRWWC 506
Query: 363 NVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAP--YDDLGKVFIYHGSAN-GINT 419
+ G FG A+ +GD+N D D+ +GAP ++ G V+++HG I+
Sbjct: 507 DAVLYGEQGHPWGRFGAALTVLGDVNGDKLTDVVIGAPGEEENRGAVYLFHGVLGPSISP 566
Query: 420 KPTQVLKGIS-----PYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTI 474
+Q + G YFG +++G DL ++ D+AVG+ V + R+RPV+ + ++
Sbjct: 567 SHSQRIAGSQLSSRLQYFGQALSGGQDLTQDGLVDLAVGA-RGQVLLLRTRPVLWVGVSM 625
Query: 475 TVTPNRI-----DLRQKTACG---APSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEK 526
P I + R++ S ICL + + S+++ L+ +
Sbjct: 626 QFIPAEIPRSAFECREQVVSEQTLVQSNICLYIDKRSKNLLGSRDLQSSVTLDLALDPGR 685
Query: 527 ERRKSGLSSRVQFRNQGSEPKYTQELTLKRQK----QKVCMEETLWLQDNIRDKLRPIPI 582
LS R F+ T+ +L R + + C L L + D + PI +
Sbjct: 686 ------LSPRATFQE-------TKNRSLSRVRVLGLKAHCENFNLLLPSCVEDSVTPITL 732
Query: 583 TASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKF 642
+ + + + + + P+L +D + + F ++ CG D++C NL + + F
Sbjct: 733 RLNFTL----VGKPLLAFRNLRPMLAADAQRYFTASLPF-EKNCGADHICQDNLGISFSF 787
Query: 643 CTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIA 702
G+ L++ ++ E+ V N DG+D++ +
Sbjct: 788 ----------------PGLKSLLVGSNLELNAEVMVWN----------DGEDSYGTTITF 821
Query: 703 TFPDTLTYSAYRE------LRAFPEKQLSCVANQNGSQ----ADCELGN-PFKRNSNVTF 751
+ P L+Y E LR+ L+C + GSQ C + + F+ + +TF
Sbjct: 822 SHPAGLSYRYVAEGQKQGQLRSL---HLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITF 878
Query: 752 YLVLSTTEVTFDTPDLDINLKLETTSN--QDNLAPITAKAKVVIELLLSVSGVAKPSQVY 809
L+T +V +P + +L T+N +N P T+K +EL + + VY
Sbjct: 879 ---LATFDV---SPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYA-------VY 925
Query: 810 FGGTVVG--EQAMK------SEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISN 861
TVV EQ K SE++ + + ++V NLG Q +S
Sbjct: 926 ---TVVSSHEQFTKYLNFSESEEKESHVAMHRYQVNNLG-------------QRDLPVSI 969
Query: 862 GKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAER 921
W V E +E +++ SH + ++I L +
Sbjct: 970 NFW--------------VPVELNQEAVWMDVEVSHPQNPSLRCSSEKIAPPASDFLAHIQ 1015
Query: 922 KYQTLNCSVNVNCVNIRC--PLRGLDSKASLILRSRL---WNSTFLEEYSKLNYLDILMR 976
K L+CS+ C+ RC P + + L+ L W L++ K++ + +
Sbjct: 1016 KNPVLDCSI-AGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQK--KVSVVSVAEI 1072
Query: 977 AFIDVTAAAENIRLPNAGTQVRVTVFPSKTVAQYSGV--PWWIILVAILAGILMLALLVF 1034
F D + ++ LP +R + TV + V P +I+ + + G+L+LAL+
Sbjct: 1073 TF-DTSVYSQ---LPGQEAFMRA---QTTTVLEKYKVHNPTPLIVGSSIGGLLLLALITA 1125
Query: 1035 ILWKCGFFKRNKKD 1048
+L+K GFFKR K+
Sbjct: 1126 VLYKVGFFKRQYKE 1139
Score = 32.0 bits (71), Expect = 3.2
Identities = 34/122 (27%), Positives = 53/122 (43%), Gaps = 21/122 (17%)
Query: 10 LYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRA 69
L L L + LG FNLDT E R + FG S+ + ++VGAP+
Sbjct: 8 LLLFTALATSLG--FNLDTEELTAFRV---DSAGFGDSVVQY------ANSWVVVGAPQK 56
Query: 70 EALPLQRANRTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVV 129
+ AN+TGGLY C + G C I + + S +G+++ S +++
Sbjct: 57 ----ITAANQTGGLYQCGYST-GACEPIGLQVPPEAVNMS-----LGLSLASTTSPSQLL 106
Query: 130 TC 131
C
Sbjct: 107 AC 108
>gi|62548866 integrin, alpha D precursor [Homo sapiens]
Length = 1161
Score = 127 bits (319), Expect = 6e-29
Identities = 204/901 (22%), Positives = 377/901 (41%), Gaps = 159/901 (17%)
Query: 189 QQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDES 248
Q+G + T D ++ GA G+++W G + N + +N+ ++
Sbjct: 352 QEGFSTALTMDGLFL--GAVGSFSWSGGAFLYPPNMSPTFINMSQENVDM---------- 399
Query: 249 LVPVPANSYLGFSLDSG--KGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHI 306
+SYLG+S + KG+ + V GAPR H+G V+ + + E
Sbjct: 400 -----RDSYLGYSTELALWKGVQN-----LVLGAPRYQHTGKAVIFTQVSRQWRKKAE-- 447
Query: 307 FDGEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYMNQQGR--WNN 363
G + S FG + VD++ DG D++ IGAP Y+++ GG V V +GR W
Sbjct: 448 VTGTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYEQTR--GGQVSVCPLPRGRVQWQC 505
Query: 364 VKPIR-LNGTKDSMFGIAVKNIGDINQDGYPDIAVGAP--YDDLGKVFIYHG-SANGINT 419
+R G FG A+ +GD+N+D D+A+GAP ++ G V+++HG S +GI+
Sbjct: 506 DAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLFHGASESGISP 565
Query: 420 KPTQVLKG--ISP---YFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTI 474
+Q + +SP YFG +++G DL ++ D+AVG+ V + RS PV+ + +
Sbjct: 566 SHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVGA-RGQVLLLRSLPVLKVGVAM 624
Query: 475 TVTPNRI--------DLRQKTACGAPSGICLQV-KSCFEYTANPAGYNPSISIVGTLEAE 525
+P + + + + +CL + KS + + I ++ +
Sbjct: 625 RFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQKSSLDQLGD---------IQSSVRFD 675
Query: 526 KERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITAS 585
L+SR F N+ P T+ TL C L L D + D + PI + +
Sbjct: 676 LALDPGRLTSRAIF-NETKNPTLTRRKTLGLGIH--CETLKLLLPDCVEDVVSPIILHLN 732
Query: 586 VEIQEPSSRRRVNSLPEVLPIL--NSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFC 643
+ R + S + P+L S + TA + ++ CG D +C +L + F
Sbjct: 733 FSL----VREPIPSPQNLRPVLAVGSQDLFTASLP---FEKNCGQDGLCEGDLGVTLSF- 784
Query: 644 TREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIAT 703
G+ L + ++ + +TV N+ G+D++ +
Sbjct: 785 ---------------SGLQTLTVGSSLELNVIVTVWNA----------GEDSYGTVVSLY 819
Query: 704 FPDTLTYSAYRELRAFPEK---QLSC----VANQNGSQADCELGNP-FKRNSNVTFYLVL 755
+P L++ + P + +L+C ++ + C + +P F SN TF +
Sbjct: 820 YPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSRCSVNHPIFHEGSNGTF---I 876
Query: 756 STTEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIEL-----LLSVSGVAKPSQVYF 810
T +V++ D L + S+++N A ++KA +EL + ++ + S YF
Sbjct: 877 VTFDVSYKATLGDRMLMRASASSENNKAS-SSKATFQLELPVKYAVYTMISRQEESTKYF 935
Query: 811 GGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVK 870
E+ MK E+ +RV NL + + ++N W + NG ++ V
Sbjct: 936 NFATSDEKKMKE-------AEHRYRVNNLSQRDLAI---SINF-WVPVLLNGV-AVWDVV 983
Query: 871 VESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSV 930
+E+ + + C ++E++ + F R L+CS+
Sbjct: 984 MEAPS-QSLPC----------------------VSERKPPQHSDFLTQISRS-PMLDCSI 1019
Query: 931 NVNCVNIRC--PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENI 988
+C+ RC P + + L+ L E K + + D + ++
Sbjct: 1020 -ADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQ-- 1076
Query: 989 RLPNAGTQVRVTV-FPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNKK 1047
LP +R + + Y+ +P II+ + + +L+LAL+ L+K GFFKR+ K
Sbjct: 1077 -LPGQEAFMRAQMEMVLEEDEVYNAIP--IIMGSSVGALLLLALITATLYKLGFFKRHYK 1133
Query: 1048 D 1048
+
Sbjct: 1134 E 1134
Score = 33.5 bits (75), Expect = 1.1
Identities = 36/118 (30%), Positives = 54/118 (45%), Gaps = 21/118 (17%)
Query: 16 LLSRLGA--AFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALP 73
LLS L + FNLD E + ++ D G FG S+ + L+VGAP L
Sbjct: 8 LLSVLASYHGFNLDVEEPTIFQE--DAGG-FGQSVVQFGGSR------LVVGAP----LE 54
Query: 74 LQRANRTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTC 131
+ AN+TG LY C A G C I + + S +G+T+ + G +++ C
Sbjct: 55 VVAANQTGRLYDC-AAATGMCQPIPLHIRPEAVNMS-----LGLTLAASTNGSRLLAC 106
>gi|29171717 glycosylphosphatidylinositol specific phospholipase D1
isoform 1 precursor [Homo sapiens]
Length = 840
Score = 59.3 bits (142), Expect = 2e-08
Identities = 52/160 (32%), Positives = 81/160 (50%), Gaps = 29/160 (18%)
Query: 317 GYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVG-GAVY-VYMNQQGRWNNVKPIRLNGTKD 374
G+ + DLN+DG D+V+GAP Y R G + G VY +Y N G + P+ L+ K+
Sbjct: 382 GWAMTSADLNQDGHGDLVVGAPGY-SRPGHIHIGRVYLIYGNDLG----LPPVDLDLDKE 436
Query: 375 S-----------MFGIAVKNIGDINQDGYPDIAVGAP------YDDLGKVFIYHGS-ANG 416
+ FG A+ + D N DG PD+AVGAP G V++Y GS G
Sbjct: 437 AHRILEGFQPSGRFGSALA-VLDFNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSKQGG 495
Query: 417 INTKPTQVLKGISPY--FGYSIAGNMDLDRNSYPDVAVGS 454
+++ P + Y G+++ D++ +S PD+ +GS
Sbjct: 496 MSSSPNITISCQDIYCNLGWTLLA-ADVNGDSEPDLVIGS 534
Score = 49.7 bits (117), Expect = 1e-05
Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 5/106 (4%)
Query: 297 KSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMN 356
K AH I +G + FG +AV+D N DG D+ +GAP GAVYVY
Sbjct: 435 KEAH----RILEGFQPSGRFGSALAVLDFNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFG 490
Query: 357 QQGRWNNVKPIRLNGTKDSMFGIAVKNI-GDINQDGYPDIAVGAPY 401
+ + P +D + + D+N D PD+ +G+P+
Sbjct: 491 SKQGGMSSSPNITISCQDIYCNLGWTLLAADVNGDSEPDLVIGSPF 536
Score = 32.0 bits (71), Expect = 3.2
Identities = 32/119 (26%), Positives = 48/119 (40%), Gaps = 18/119 (15%)
Query: 258 LGFSLDSGK-------------GIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPE 304
LG SL SG G + D+++ V+ H G + A L
Sbjct: 647 LGTSLSSGHVLMNGTLKQVLLVGAPTYDDVSKVAFLTVTLHQGGATRMYALTSDAQPLLL 706
Query: 305 HIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFD--RDGEVG---GAVYVYMNQQ 358
F G+ S FG + + DL+ DG +I++ AP G +G G VYVY ++
Sbjct: 707 STFSGDRRFSRFGGVLHLSDLDDDGLDEIIMAAPLRIADVTSGLIGGEDGRVYVYNGKE 765
>gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
sapiens]
Length = 462
Score = 38.5 bits (88), Expect = 0.034
Identities = 105/478 (21%), Positives = 184/478 (38%), Gaps = 108/478 (22%)
Query: 623 KEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSP 682
++ CG D++C NL + + F G+ L++ ++ E+ V N
Sbjct: 17 EKNCGADHICQDNLGISFSF----------------PGLKSLLVGSNLELNAEVMVWN-- 58
Query: 683 SNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRE------LRAFPEKQLSCVANQNGSQA- 735
DG+D++ + + P L+Y E LR+ L+C + GSQ
Sbjct: 59 --------DGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSL---HLTCDSAPVGSQGT 107
Query: 736 ---DCELGNP-FKRNSNVTFYLVLSTTEVTFD-TPDLDINLKLETTSNQDNLAPITAKAK 790
C + + F+ + +TF TFD +P + +L T+N + +K
Sbjct: 108 WSTSCRINHLIFRGGAQITFL-------ATFDVSPKAVLGDRLLLTANVSSENNTPRTSK 160
Query: 791 VVIELLLSVSGVAKPSQVYFGGTVVG--EQAMK------SEDEVGSLIEYEFR------- 835
+L L V Y TVV EQ K SE++ + + ++
Sbjct: 161 TTFQLELPVK--------YAVYTVVSSHEQFTKYLNFSESEEKESHVAMHRYQAGGGDAG 212
Query: 836 ----VINLGK-----------PLTNLGTAT---LNIQWPKEISNGKWLLYLVKVESKGLE 877
V NLG+ P+ A + + P+ + WLL+ L
Sbjct: 213 DWAGVNNLGQRDLPVSINFWVPVELNQEAVWMDVEVSHPQVPKDCMWLLHECPFYLDSLC 272
Query: 878 KVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNI 937
+ P +L L + R +EK F L +K L+CS+ C+
Sbjct: 273 PMWV-PDVPAETLVLCIFPQNPSLRCSSEKIAPPASDF-LAHIQKNPVLDCSI-AGCLRF 329
Query: 938 RC--PLRGLDSKASLILRSRL---WNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPN 992
RC P + + L+ L W L++ K++ + + F D + ++ LP
Sbjct: 330 RCDVPSFSVQEELDFTLKGNLSFGWVRQILQK--KVSVVSVAEITF-DTSVYSQ---LPG 383
Query: 993 AGTQVRVTVFPSKTVAQYSGV--PWWIILVAILAGILMLALLVFILWKCGFFKRNKKD 1048
+R + TV + V P +I+ + + G+L+LAL+ +L+K GFFKR K+
Sbjct: 384 QEAFMRAQ---TTTVLEKYKVHNPTPLIVGSSIGGLLLLALITAVLYKVGFFKRQYKE 438
>gi|109891938 disks large-associated protein 4 isoform c [Homo
sapiens]
Length = 285
Score = 34.7 bits (78), Expect = 0.50
Identities = 21/71 (29%), Positives = 33/71 (46%)
Query: 861 NGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAE 920
+G W L L++ E++ LE C+ KE NL+E + + Q+ ++KF F
Sbjct: 96 DGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRG 155
Query: 921 RKYQTLNCSVN 931
Q LN N
Sbjct: 156 LCEQNLNPDAN 166
>gi|34335251 disks large-associated protein 4 isoform b [Homo
sapiens]
Length = 453
Score = 34.7 bits (78), Expect = 0.50
Identities = 21/71 (29%), Positives = 33/71 (46%)
Query: 861 NGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAE 920
+G W L L++ E++ LE C+ KE NL+E + + Q+ ++KF F
Sbjct: 264 DGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRG 323
Query: 921 RKYQTLNCSVN 931
Q LN N
Sbjct: 324 LCEQNLNPDAN 334
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,676,921
Number of Sequences: 37866
Number of extensions: 1951417
Number of successful extensions: 4689
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 4297
Number of HSP's gapped (non-prelim): 82
length of query: 1073
length of database: 18,247,518
effective HSP length: 113
effective length of query: 960
effective length of database: 13,968,660
effective search space: 13409913600
effective search space used: 13409913600
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.