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Search of human proteins with 239755176
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239755176 PREDICTED: similar to solute carrier family 25,
member 25 isoform 2 [Homo sapiens]
(469 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 937 0.0
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 937 0.0
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 832 0.0
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 832 0.0
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 832 0.0
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 731 0.0
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 605 e-173
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 585 e-167
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 584 e-167
gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 324 1e-88
gi|60460887 solute carrier family 25, member 42 [Homo sapiens] 176 4e-44
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 171 1e-42
gi|21687151 mitochondrial solute carrier protein [Homo sapiens] 125 1e-28
gi|13775208 solute carrier family 25 (mitochondrial carrier; ade... 116 5e-26
gi|156071459 solute carrier family 25, member 5 [Homo sapiens] 115 7e-26
gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 115 1e-25
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 115 1e-25
gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 115 1e-25
gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 115 1e-25
gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 113 3e-25
gi|55749577 solute carrier family 25 (mitochondrial carrier; ade... 113 4e-25
gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 108 8e-24
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 106 5e-23
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 106 5e-23
gi|157388991 solute carrier family 25, member 36 isoform b [Homo... 105 1e-22
gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens] 102 1e-21
gi|58197562 solute carrier family 25, member 30 [Homo sapiens] 100 5e-21
gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 93 5e-19
gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo ... 93 6e-19
gi|149274643 solute carrier family 25, member 28 [Homo sapiens] 92 1e-18
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 937 bits (2423), Expect = 0.0
Identities = 469/469 (100%), Positives = 469/469 (100%)
Query: 1 MLCLCLYVPVIGEAQTEFQYFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGD 60
MLCLCLYVPVIGEAQTEFQYFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGD
Sbjct: 1 MLCLCLYVPVIGEAQTEFQYFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGD 60
Query: 61 KDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAE 120
KDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAE
Sbjct: 61 KDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAE 120
Query: 121 KILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEE 180
KILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEE
Sbjct: 121 KILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEE 180
Query: 181 RQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 240
RQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR
Sbjct: 181 RQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 240
Query: 241 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 300
SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP
Sbjct: 241 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 300
Query: 301 MEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 360
MEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL
Sbjct: 301 MEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 360
Query: 361 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMS 420
KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMS
Sbjct: 361 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMS 420
Query: 421 SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR
Sbjct: 421 SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 937 bits (2423), Expect = 0.0
Identities = 469/469 (100%), Positives = 469/469 (100%)
Query: 1 MLCLCLYVPVIGEAQTEFQYFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGD 60
MLCLCLYVPVIGEAQTEFQYFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGD
Sbjct: 1 MLCLCLYVPVIGEAQTEFQYFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGD 60
Query: 61 KDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAE 120
KDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAE
Sbjct: 61 KDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAE 120
Query: 121 KILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEE 180
KILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEE
Sbjct: 121 KILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEE 180
Query: 181 RQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 240
RQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR
Sbjct: 181 RQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 240
Query: 241 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 300
SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP
Sbjct: 241 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 300
Query: 301 MEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 360
MEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL
Sbjct: 301 MEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 360
Query: 361 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMS 420
KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMS
Sbjct: 361 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMS 420
Query: 421 SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR
Sbjct: 421 SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 832 bits (2150), Expect = 0.0
Identities = 417/420 (99%), Positives = 419/420 (99%)
Query: 50 QWKQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRD 109
Q+ +KIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRD
Sbjct: 70 QFPKKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRD 129
Query: 110 LGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGEN 169
LGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGEN
Sbjct: 130 LGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGEN 189
Query: 170 LTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGG 229
LTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGG
Sbjct: 190 LTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGG 249
Query: 230 FTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSL 289
FTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSL
Sbjct: 250 FTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSL 309
Query: 290 AGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPY 349
AGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPY
Sbjct: 310 AGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPY 369
Query: 350 AGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQA 409
AGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQA
Sbjct: 370 AGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQA 429
Query: 410 SIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
SIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR
Sbjct: 430 SIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 489
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 832 bits (2149), Expect = 0.0
Identities = 417/417 (100%), Positives = 417/417 (100%)
Query: 53 QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 112
QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV
Sbjct: 87 QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 146
Query: 113 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 172
KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV
Sbjct: 147 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 206
Query: 173 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 232
PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ
Sbjct: 207 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 266
Query: 233 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 292
MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA
Sbjct: 267 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 326
Query: 293 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 352
IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI
Sbjct: 327 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 386
Query: 353 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 412
DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE
Sbjct: 387 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 446
Query: 413 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR
Sbjct: 447 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 503
Score = 39.7 bits (91), Expect = 0.006
Identities = 20/65 (30%), Positives = 38/65 (58%)
Query: 78 DHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWN 137
DH +L +F++LD DG + ++ LR LG+ +E + +KI+++ DK+ +D+
Sbjct: 45 DHRLRLWRLFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFE 104
Query: 138 EWRDY 142
E+ Y
Sbjct: 105 EFVHY 109
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 832 bits (2149), Expect = 0.0
Identities = 417/417 (100%), Positives = 417/417 (100%)
Query: 53 QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 112
QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV
Sbjct: 87 QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 146
Query: 113 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 172
KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV
Sbjct: 147 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 206
Query: 173 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 232
PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ
Sbjct: 207 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 266
Query: 233 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 292
MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA
Sbjct: 267 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 326
Query: 293 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 352
IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI
Sbjct: 327 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 386
Query: 353 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 412
DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE
Sbjct: 387 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 446
Query: 413 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR
Sbjct: 447 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 503
Score = 39.7 bits (91), Expect = 0.006
Identities = 20/65 (30%), Positives = 38/65 (58%)
Query: 78 DHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWN 137
DH +L +F++LD DG + ++ LR LG+ +E + +KI+++ DK+ +D+
Sbjct: 45 DHRLRLWRLFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFE 104
Query: 138 EWRDY 142
E+ Y
Sbjct: 105 EFVHY 109
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 731 bits (1886), Expect = 0.0
Identities = 366/366 (100%), Positives = 366/366 (100%)
Query: 104 MQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTI 163
MQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTI
Sbjct: 1 MQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTI 60
Query: 164 FDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNN 223
FDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNN
Sbjct: 61 FDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNN 120
Query: 224 MGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHER 283
MGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHER
Sbjct: 121 MGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHER 180
Query: 284 LVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNM 343
LVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNM
Sbjct: 181 LVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNM 240
Query: 344 LGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRT 403
LGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRT
Sbjct: 241 LGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRT 300
Query: 404 RMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKIT 463
RMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKIT
Sbjct: 301 RMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKIT 360
Query: 464 LGVQSR 469
LGVQSR
Sbjct: 361 LGVQSR 366
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 605 bits (1560), Expect = e-173
Identities = 296/418 (70%), Positives = 344/418 (82%)
Query: 52 KQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLG 111
+Q I GD D DG LD EEF YLQ+ E++L L+F SLD+ DG ID EI QS R LG
Sbjct: 51 QQGISSEGDADPDGGLDLEEFSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRALG 110
Query: 112 VKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLT 171
+ IS +QAEKIL SMD++GTMTIDW EWRD+ LLH +EN+ +++ +WKHST+ D+GE LT
Sbjct: 111 ISISLEQAEKILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLT 170
Query: 172 VPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFT 231
VPDEF+ +E+ TGMWW+ LVAG AGAVSRT TAPLDRLKV MQVHAS++N + I+GG
Sbjct: 171 VPDEFSKQEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLR 230
Query: 232 QMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAG 291
M+ EGG RSLWRGNGINVLKIAPESAIKFMAYEQIKR + QETL + ER VAGSLAG
Sbjct: 231 SMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAG 290
Query: 292 AIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
A AQ+ IYPMEVLKTR+ LR+TGQY G+LDCARRIL REG AFY+GY+PN+LGIIPYAG
Sbjct: 291 ATAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAG 350
Query: 352 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 411
IDLAVYETLKN WLQ Y+ +SADPG+ VLLACGT+SSTCGQ+ASYPLALVRTRMQAQASI
Sbjct: 351 IDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASI 410
Query: 412 EGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
EG P+++M L +HIL EG GLYRG+APNFMKVIPAVSISYVVYEN+K LGV SR
Sbjct: 411 EGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR 468
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 585 bits (1507), Expect = e-167
Identities = 276/418 (66%), Positives = 347/418 (83%)
Query: 52 KQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLG 111
++KI GD + DG+LDFEEF+ YL+DHEKK++L FKSLDK NDG+I+A EI+QSL+ LG
Sbjct: 60 EEKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLG 119
Query: 112 VKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLT 171
+ ISEQQAE IL+S+D +GTMT+DWNEWRDY L +PV +I EII +WKHST D+G++LT
Sbjct: 120 LTISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLT 179
Query: 172 VPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFT 231
+PDEFT +E+++G WWR L+AGG AGAVSRT TAPLDRLK++MQVH S+S+ M I GGF
Sbjct: 180 IPDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFR 239
Query: 232 QMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAG 291
QM++EGG RSLWRGNG NV+KIAPE+A+KF AYEQ K+L+ + + + ER ++GS+AG
Sbjct: 240 QMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAG 299
Query: 292 AIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
A AQ+ IYPMEV+KTR+A+ KTGQYSG+ DCA++IL EG+ AFYKGYVPN+LGIIPYAG
Sbjct: 300 ATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAG 359
Query: 352 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 411
IDLAVYE LK+ WL ++A +S +PGV VLL CG +SSTCGQLASYPLALVRTRMQAQA +
Sbjct: 360 IDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAML 419
Query: 412 EGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
EG+P++ M LF+ I+ EG GLYRG+ PNFMKV+PAV ISYVVYEN+K TLGV +
Sbjct: 420 EGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 477
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 584 bits (1505), Expect = e-167
Identities = 276/417 (66%), Positives = 346/417 (82%)
Query: 53 QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 112
+KI GD + DG+LDFEEF+ YL+DHEKK++L FKSLDK NDG+I+A EI+QSL+ LG+
Sbjct: 42 KKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGL 101
Query: 113 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 172
ISEQQAE IL+S+D +GTMT+DWNEWRDY L +PV +I EII +WKHST D+G++LT+
Sbjct: 102 TISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTI 161
Query: 173 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 232
PDEFT +E+++G WWR L+AGG AGAVSRT TAPLDRLK++MQVH S+S+ M I GGF Q
Sbjct: 162 PDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQ 221
Query: 233 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 292
M++EGG RSLWRGNG NV+KIAPE+A+KF AYEQ K+L+ + + + ER ++GS+AGA
Sbjct: 222 MVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGA 281
Query: 293 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 352
AQ+ IYPMEV+KTR+A+ KTGQYSG+ DCA++IL EG+ AFYKGYVPN+LGIIPYAGI
Sbjct: 282 TAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGI 341
Query: 353 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 412
DLAVYE LK+ WL ++A +S +PGV VLL CG +SSTCGQLASYPLALVRTRMQAQA +E
Sbjct: 342 DLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLE 401
Query: 413 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
G+P++ M LF+ I+ EG GLYRG+ PNFMKV+PAV ISYVVYEN+K TLGV +
Sbjct: 402 GSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 458
>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
Length = 370
Score = 324 bits (830), Expect = 1e-88
Identities = 172/304 (56%), Positives = 217/304 (71%), Gaps = 3/304 (0%)
Query: 163 IFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSN 222
+ D GE L VP E + + +W + L++G AGAVSRT TAPLDR KV MQV++S++N
Sbjct: 70 VLDTGEQLMVPVEVLEVDNKEALW-KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTN 128
Query: 223 NMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHE 282
++GG M++EGG RSLWRGNGINVLKIAPE AIKF +EQ K Q + E
Sbjct: 129 FTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQE 188
Query: 283 RLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPN 342
RL+AGSLA AI+Q+ I PMEVLKTR+ LR+TGQY G+LDCAR+IL REG A Y+GY+PN
Sbjct: 189 RLLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPN 248
Query: 343 MLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVR 402
MLGIIPYA DLAVYE L+ W++ + DP V L+ T+S+TCGQ+ASYPL LVR
Sbjct: 249 MLGIIPYACTDLAVYEMLQCFWVKS-GRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVR 307
Query: 403 TRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 462
TRMQAQ ++EG+ TM + + IL +G GLYRG+ P +KV+PA ISYVVYE +K
Sbjct: 308 TRMQAQDTVEGS-NPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
Query: 463 TLGV 466
TLG+
Sbjct: 367 TLGI 370
>gi|60460887 solute carrier family 25, member 42 [Homo sapiens]
Length = 318
Score = 176 bits (446), Expect = 4e-44
Identities = 106/280 (37%), Positives = 157/280 (56%), Gaps = 8/280 (2%)
Query: 190 LVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGIN 249
L+ G AGA+++T APLDR K++ QV + R + G SLWRGN
Sbjct: 37 LLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSAT 96
Query: 250 VLKIAPESAIKFMAYEQIKRLVGSDQ----ETLRIHERLVAGSLAGAIAQSSIYPMEVLK 305
++++ P +AI+F A+E+ KR++GS E L RL AG+LAG A S YP+++++
Sbjct: 97 MVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVR 156
Query: 306 TRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWL 365
RMA+ YS + RI EG+ Y G++P +LG+IPYAG+ YETLK+ L
Sbjct: 157 ARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKS--L 214
Query: 366 QHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKH 425
P F + G + GQ ASYPL +VR RMQ A + G P +++ +
Sbjct: 215 HREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQT-AGVTGYPRASIARTLRT 273
Query: 426 ILRTEGAF-GLYRGLAPNFMKVIPAVSISYVVYENLKITL 464
I+R EGA GLY+GL+ N++K AV IS+ ++ ++I L
Sbjct: 274 IVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQIML 313
Score = 77.8 bits (190), Expect = 2e-14
Identities = 53/197 (26%), Positives = 93/197 (47%), Gaps = 14/197 (7%)
Query: 271 VGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRI---L 327
V S ++ ++ L+ G+LAGA+A++++ P++ +T++ + + + + R +
Sbjct: 24 VSSKRDHRQVLSSLLPGALAGALAKTAVAPLD--RTKIIFQVSSKRFSAKEAFRVLYYTY 81
Query: 328 AREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMS 387
EG + ++G M+ ++PYA I + +E K +Y + L G ++
Sbjct: 82 LNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALA 141
Query: 388 STCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFK---HILRTEGAFGLYRGLAPNFM 444
T +YPL LVR RM P+ S++F I R EG LY G P +
Sbjct: 142 GTTAASLTYPLDLVRARMAV------TPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVL 195
Query: 445 KVIPAVSISYVVYENLK 461
VIP +S+ YE LK
Sbjct: 196 GVIPYAGLSFFTYETLK 212
Score = 30.4 bits (67), Expect = 3.6
Identities = 19/82 (23%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 384 GTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNF 443
G ++ + A PL + Q + A E + ++ EG L+RG +
Sbjct: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYL--NEGFLSLWRGNSATM 97
Query: 444 MKVIPAVSISYVVYENLKITLG 465
++V+P +I + +E K LG
Sbjct: 98 VRVVPYAAIQFSAHEEYKRILG 119
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 171 bits (434), Expect = 1e-42
Identities = 102/296 (34%), Positives = 164/296 (55%), Gaps = 15/296 (5%)
Query: 181 RQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 240
R+ W R +AGG AG ++T APLDR+KVL+Q H ++G+ + ++ G
Sbjct: 31 RRDFYWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFL 90
Query: 241 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 300
L++GNG +++I P AI+FMA+E K L+ + RL+AGS+AG A YP
Sbjct: 91 GLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMTAVICTYP 150
Query: 301 MEVLKTRMALRKTGQ--YSGMLDCARRILARE-GVAAFYKGYVPNMLGIIPYAGIDLAVY 357
+++++ R+A + G+ Y+G++ + I A+E G FY+G +P +LG+ PYAG+ +
Sbjct: 151 LDMVRVRLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTF 210
Query: 358 ETLKNAWLQHYAV-----NSADPGVFVL-----LACGTMSSTCGQLASYPLALVRTRMQA 407
TLK+ L H +S +P V VL L CG ++ Q SYP + R RMQ
Sbjct: 211 GTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTRRRMQL 270
Query: 408 QASI-EGAPEVTMSSLFKHILRTEG-AFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
+ E +TM K++ G GLYRGL+ N+++ IP+ ++++ YE +K
Sbjct: 271 GTVLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMK 326
Score = 37.7 bits (86), Expect = 0.023
Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 14/90 (15%)
Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHA---------SRSNNMGIVGGFTQMIREGGA 239
+L+ GG AGA+++T + P D + MQ+ + + M V G G
Sbjct: 243 NLLCGGVAGAIAQTISYPFDVTRRRMQLGTVLPEFEKCLTMRDTMKYVYG-----HHGIR 297
Query: 240 RSLWRGNGINVLKIAPESAIKFMAYEQIKR 269
+ L+RG +N ++ P A+ F YE +K+
Sbjct: 298 KGLYRGLSLNYIRCIPSQAVAFTTYELMKQ 327
>gi|21687151 mitochondrial solute carrier protein [Homo sapiens]
Length = 341
Score = 125 bits (313), Expect = 1e-28
Identities = 84/285 (29%), Positives = 139/285 (48%), Gaps = 18/285 (6%)
Query: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 247
+ L+ G AG +S + TAPL+ VL QV R + G ++ R G R+LW+GN
Sbjct: 14 QRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNA 73
Query: 248 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 307
+ L++ P SA++ AY + L D + ++AGSLAG ++ YP +++KTR
Sbjct: 74 VACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTR 133
Query: 308 MALRK--TGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWL 365
+ ++ Y G+L I +EG A Y+G ++G +P++ L VY L+ W
Sbjct: 134 LIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIW- 192
Query: 366 QHYAVNSADPGVFVL---LACGTMSSTCGQLASYPLALVRTRMQAQASI---EGAPEVTM 419
+ F L A +++ Q S+P V+ +MQAQ+ G +V
Sbjct: 193 ------NGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHF 246
Query: 420 S---SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
S F+ I++ +G GL+ GL N +K++P I + +E K
Sbjct: 247 SGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCK 291
Score = 84.3 bits (207), Expect = 2e-16
Identities = 52/189 (27%), Positives = 93/189 (49%), Gaps = 10/189 (5%)
Query: 187 WRHLVAGGGAGAVSRTCTAPLDRLKV-LMQVHASRSNNMGIVGGFTQMIREGGARSLWRG 245
W ++AG AG VS T P D +K L+ + + G++ F+ + ++ G +L+RG
Sbjct: 107 WSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRG 166
Query: 246 NGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLK 305
+ V+ P SA + Y ++++ ++ + + LA A+ Q+ +P E +K
Sbjct: 167 VSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVK 226
Query: 306 TRMA-----LRKTG----QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAV 356
+M L +G +SG +DC R+I+ +GV + G N+L I+PY GI +
Sbjct: 227 RKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFST 286
Query: 357 YETLKNAWL 365
+E K L
Sbjct: 287 FEFCKRICL 295
>gi|13775208 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 31 [Homo
sapiens]
Length = 315
Score = 116 bits (290), Expect = 5e-26
Identities = 83/290 (28%), Positives = 137/290 (47%), Gaps = 22/290 (7%)
Query: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS------RSNNMGIVGGFTQMIREGGARS 241
+ L+AGG A AVS+T AP++R+K+L+QV AS + G+V ++ RE G S
Sbjct: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFS 81
Query: 242 LWRGNGINVLKIAPESAIKFMAYEQIKRL----VGSDQETLR-IHERLVAGSLAGAIAQS 296
WRGN NV++ P A+ F ++ K+L V +++ R L +G AGA +
Sbjct: 82 FWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLC 141
Query: 297 SIYPMEVLKTRMAL-----RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
+YP++ +TR+ + + Q+ G+ DC +I +G+A Y+G+ ++ GII Y
Sbjct: 142 VVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRA 201
Query: 352 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 411
Y+T+K V + +TC + SYP VR RM Q+
Sbjct: 202 SYFGAYDTVKG-----LLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGE 256
Query: 412 EGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
F I + EG +RG N ++ ++ V+Y+ +K
Sbjct: 257 AKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGG-ALVLVLYDKIK 305
Score = 62.0 bits (149), Expect = 1e-09
Identities = 49/177 (27%), Positives = 84/177 (47%), Gaps = 15/177 (8%)
Query: 179 EERQTGMWWRHLVA-GGGAGAVSRTCTAPLDRLKVLMQVHASRSNN----MGIVGGFTQM 233
+E+Q W+ +A GG AGA S PLD + + V + G+ ++
Sbjct: 117 KEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKI 176
Query: 234 IREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAI 293
+ G L++G G++V I A F AY+ +K L+ ++T LV+ +A +
Sbjct: 177 AKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKT----PFLVSFFIAQVV 232
Query: 294 AQSS---IYPMEVLKTRMALRK---TGQYSGMLDCARRILAREGVAAFYKGYVPNML 344
S YP + ++ RM ++ QY G LDC +I EG+++F++G N+L
Sbjct: 233 TTCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVL 289
>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
Length = 298
Score = 115 bits (289), Expect = 7e-26
Identities = 88/296 (29%), Positives = 148/296 (50%), Gaps = 32/296 (10%)
Query: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASR-----SNNMGIVGGFTQMIREGGARS 241
+ +AGG A A+S+T AP++R+K+L+QV HAS+ GI+ ++ +E G S
Sbjct: 10 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69
Query: 242 LWRGNGINVLKIAPESAIKFMAYEQIKR--LVGSDQET---LRIHERLVAGSLAGAIAQS 296
WRGN NV++ P A+ F ++ K+ L G D+ T L L +G AGA +
Sbjct: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129
Query: 297 SIYPMEVLKTRMA--LRKTG---QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
+YP++ +TR+A + K G ++ G+ DC +I +G+ Y+G+ ++ GII Y
Sbjct: 130 FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRA 189
Query: 352 IDLAVYETLKNAWLQHYAVNSADPG----VFVLLACGTMSSTCGQLASYPLALVRTRMQA 407
+Y+T K DP V + T+++ G L SYP VR RM
Sbjct: 190 AYFGIYDTAKGM--------LPDPKNTHIVISWMIAQTVTAVAG-LTSYPFDTVRRRMMM 240
Query: 408 QASIEGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Q+ +G + +L ++ I R EG ++G N ++ + + V+Y+ +K
Sbjct: 241 QSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDEIK 295
>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
Length = 298
Score = 115 bits (287), Expect = 1e-25
Identities = 89/296 (30%), Positives = 149/296 (50%), Gaps = 32/296 (10%)
Query: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASRS-----NNMGIVGGFTQMIREGGARS 241
+ +AGG A A+S+T AP++R+K+L+QV HAS+ GIV ++ +E G S
Sbjct: 10 KDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLS 69
Query: 242 LWRGNGINVLKIAPESAIKFMAYEQIKR--LVGSDQET---LRIHERLVAGSLAGAIAQS 296
WRGN NV++ P A+ F ++ K+ L G D+ T L +G AGA +
Sbjct: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATSLC 129
Query: 297 SIYPMEVLKTRMA--LRKTG---QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
+YP++ +TR+A + K+G ++ G+ DC +I +G+ Y+G+ ++ GII Y
Sbjct: 130 FVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYRA 189
Query: 352 IDLAVYETLKNAWLQHYAVNSADPG----VFVLLACGTMSSTCGQLASYPLALVRTRMQA 407
VY+T K DP V + T+++ G + SYP VR RM
Sbjct: 190 AYFGVYDTAKGM--------LPDPKNTHIVVSWMIAQTVTAVAG-VVSYPFDTVRRRMMM 240
Query: 408 QASIEGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Q+ +GA + ++ ++ I R EG ++G N ++ + + V+Y+ LK
Sbjct: 241 QSGRKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDELK 295
Score = 63.9 bits (154), Expect = 3e-10
Identities = 46/197 (23%), Positives = 90/197 (45%), Gaps = 10/197 (5%)
Query: 275 QETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTG-------QYSGMLDCARRIL 327
++ + + +AG +A AI+++++ P+E +K + ++ QY G++DC RI
Sbjct: 3 EQAISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIP 62
Query: 328 AREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFV-LLACGTM 386
+GV +F++G + N++ P ++ A + K +L ++ F LA G
Sbjct: 63 KEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGA 122
Query: 387 SSTCGQLASYPLALVRTRMQAQASIEGAPEV--TMSSLFKHILRTEGAFGLYRGLAPNFM 444
+ YPL RTR+ A G + I +++G GLY+G + +
Sbjct: 123 AGATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQ 182
Query: 445 KVIPAVSISYVVYENLK 461
+I + + VY+ K
Sbjct: 183 GIIIYRAAYFGVYDTAK 199
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 115 bits (287), Expect = 1e-25
Identities = 75/285 (26%), Positives = 134/285 (47%), Gaps = 17/285 (5%)
Query: 191 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGARSLW 243
VAG +G V+R +P D +K+ Q+ R + GI+ Q+++E G + W
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 244 RGNGINVLKIAPESAIKFMAYEQIKRLV--GSDQETLRIHERLVAGSLAGAIAQSSIYPM 301
+G+ + A++F+++E + LV GS + V G LA +A +++P+
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
Query: 302 EVLKTRMALRKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 360
+VL+TR A + + Y+ + + EG FYKG P ++ I PYAG+ + Y +L
Sbjct: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199
Query: 361 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQ------AQASIEGA 414
K+ + L CG+ + + +YPL L + R+Q A+A+
Sbjct: 200 KHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQV 259
Query: 415 PEVT-MSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 458
+ K +L+ EGA G ++GL+P+ +K + + YE
Sbjct: 260 RRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 85.9 bits (211), Expect = 7e-17
Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 16/187 (8%)
Query: 285 VAGSLAGAIAQSSIYPMEVLKTRMALRK--------TGQYSGMLDCARRILAREGVAAFY 336
VAGS++G + ++ I P +V+K R L+ + +Y G+L +R+IL EG AF+
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 337 KGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASY 396
KG+VP + I Y + +E L L H V CG +++ L +
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTE--LVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137
Query: 397 PLALVRTRMQAQASIEGAPEV--TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISY 454
P+ ++RTR AQ G P+V T+ + R+EG Y+GLAP + + P + +
Sbjct: 138 PVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193
Query: 455 VVYENLK 461
Y +LK
Sbjct: 194 SCYSSLK 200
Score = 73.6 bits (179), Expect = 4e-13
Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 20/193 (10%)
Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGI 248
H V GG A ++ P+D L+ + M R G + ++G
Sbjct: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180
Query: 249 NVLKIAPESAIKFMAYEQIKRLV-------GSDQETLRIHERLVAGSLAGAIAQSSIYPM 301
++ I P + ++F Y +K L G E L + L+ GS AG I+++ YP+
Sbjct: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL---QNLLCGSGAGVISKTLTYPL 237
Query: 302 EVLKTRM----------ALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
++ K R+ A + +Y G++DCA+++L +EG F+KG P++L G
Sbjct: 238 DLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTG 297
Query: 352 IDLAVYETLKNAW 364
YE N +
Sbjct: 298 FMFFSYEFFCNVF 310
Score = 43.1 bits (100), Expect = 5e-04
Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 9/87 (10%)
Query: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV----HASRS-----NNMGIVGGFTQMIREGG 238
++L+ G GAG +S+T T PLD K +QV HA + G++ Q++++ G
Sbjct: 218 QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEG 277
Query: 239 ARSLWRGNGINVLKIAPESAIKFMAYE 265
A ++G ++LK A + F +YE
Sbjct: 278 ALGFFKGLSPSLLKAALSTGFMFFSYE 304
>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 115 bits (287), Expect = 1e-25
Identities = 75/285 (26%), Positives = 134/285 (47%), Gaps = 17/285 (5%)
Query: 191 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGARSLW 243
VAG +G V+R +P D +K+ Q+ R + GI+ Q+++E G + W
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 244 RGNGINVLKIAPESAIKFMAYEQIKRLV--GSDQETLRIHERLVAGSLAGAIAQSSIYPM 301
+G+ + A++F+++E + LV GS + V G LA +A +++P+
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
Query: 302 EVLKTRMALRKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 360
+VL+TR A + + Y+ + + EG FYKG P ++ I PYAG+ + Y +L
Sbjct: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199
Query: 361 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQ------AQASIEGA 414
K+ + L CG+ + + +YPL L + R+Q A+A+
Sbjct: 200 KHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQV 259
Query: 415 PEVT-MSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 458
+ K +L+ EGA G ++GL+P+ +K + + YE
Sbjct: 260 RRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 85.9 bits (211), Expect = 7e-17
Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 16/187 (8%)
Query: 285 VAGSLAGAIAQSSIYPMEVLKTRMALRK--------TGQYSGMLDCARRILAREGVAAFY 336
VAGS++G + ++ I P +V+K R L+ + +Y G+L +R+IL EG AF+
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 337 KGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASY 396
KG+VP + I Y + +E L L H V CG +++ L +
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTE--LVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137
Query: 397 PLALVRTRMQAQASIEGAPEV--TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISY 454
P+ ++RTR AQ G P+V T+ + R+EG Y+GLAP + + P + +
Sbjct: 138 PVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193
Query: 455 VVYENLK 461
Y +LK
Sbjct: 194 SCYSSLK 200
Score = 73.6 bits (179), Expect = 4e-13
Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 20/193 (10%)
Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGI 248
H V GG A ++ P+D L+ + M R G + ++G
Sbjct: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180
Query: 249 NVLKIAPESAIKFMAYEQIKRLV-------GSDQETLRIHERLVAGSLAGAIAQSSIYPM 301
++ I P + ++F Y +K L G E L + L+ GS AG I+++ YP+
Sbjct: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL---QNLLCGSGAGVISKTLTYPL 237
Query: 302 EVLKTRM----------ALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
++ K R+ A + +Y G++DCA+++L +EG F+KG P++L G
Sbjct: 238 DLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTG 297
Query: 352 IDLAVYETLKNAW 364
YE N +
Sbjct: 298 FMFFSYEFFCNVF 310
Score = 43.1 bits (100), Expect = 5e-04
Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 9/87 (10%)
Query: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV----HASRS-----NNMGIVGGFTQMIREGG 238
++L+ G GAG +S+T T PLD K +QV HA + G++ Q++++ G
Sbjct: 218 QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEG 277
Query: 239 ARSLWRGNGINVLKIAPESAIKFMAYE 265
A ++G ++LK A + F +YE
Sbjct: 278 ALGFFKGLSPSLLKAALSTGFMFFSYE 304
>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 115 bits (287), Expect = 1e-25
Identities = 75/285 (26%), Positives = 134/285 (47%), Gaps = 17/285 (5%)
Query: 191 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGARSLW 243
VAG +G V+R +P D +K+ Q+ R + GI+ Q+++E G + W
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 244 RGNGINVLKIAPESAIKFMAYEQIKRLV--GSDQETLRIHERLVAGSLAGAIAQSSIYPM 301
+G+ + A++F+++E + LV GS + V G LA +A +++P+
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
Query: 302 EVLKTRMALRKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETL 360
+VL+TR A + + Y+ + + EG FYKG P ++ I PYAG+ + Y +L
Sbjct: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199
Query: 361 KNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQ------AQASIEGA 414
K+ + L CG+ + + +YPL L + R+Q A+A+
Sbjct: 200 KHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQV 259
Query: 415 PEVT-MSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 458
+ K +L+ EGA G ++GL+P+ +K + + YE
Sbjct: 260 RRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 85.9 bits (211), Expect = 7e-17
Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 16/187 (8%)
Query: 285 VAGSLAGAIAQSSIYPMEVLKTRMALRK--------TGQYSGMLDCARRILAREGVAAFY 336
VAGS++G + ++ I P +V+K R L+ + +Y G+L +R+IL EG AF+
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 337 KGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASY 396
KG+VP + I Y + +E L L H V CG +++ L +
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTE--LVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137
Query: 397 PLALVRTRMQAQASIEGAPEV--TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISY 454
P+ ++RTR AQ G P+V T+ + R+EG Y+GLAP + + P + +
Sbjct: 138 PVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193
Query: 455 VVYENLK 461
Y +LK
Sbjct: 194 SCYSSLK 200
Score = 73.6 bits (179), Expect = 4e-13
Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 20/193 (10%)
Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGI 248
H V GG A ++ P+D L+ + M R G + ++G
Sbjct: 121 HFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAP 180
Query: 249 NVLKIAPESAIKFMAYEQIKRLV-------GSDQETLRIHERLVAGSLAGAIAQSSIYPM 301
++ I P + ++F Y +K L G E L + L+ GS AG I+++ YP+
Sbjct: 181 TLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL---QNLLCGSGAGVISKTLTYPL 237
Query: 302 EVLKTRM----------ALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
++ K R+ A + +Y G++DCA+++L +EG F+KG P++L G
Sbjct: 238 DLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTG 297
Query: 352 IDLAVYETLKNAW 364
YE N +
Sbjct: 298 FMFFSYEFFCNVF 310
Score = 43.1 bits (100), Expect = 5e-04
Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 9/87 (10%)
Query: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV----HASRS-----NNMGIVGGFTQMIREGG 238
++L+ G GAG +S+T T PLD K +QV HA + G++ Q++++ G
Sbjct: 218 QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEG 277
Query: 239 ARSLWRGNGINVLKIAPESAIKFMAYE 265
A ++G ++LK A + F +YE
Sbjct: 278 ALGFFKGLSPSLLKAALSTGFMFFSYE 304
>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
Length = 315
Score = 113 bits (283), Expect = 3e-25
Identities = 86/286 (30%), Positives = 128/286 (44%), Gaps = 17/286 (5%)
Query: 187 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS---RSNNMGIVGGFTQMIREGGARSLW 243
+ +L+AG G +S PLD +K+ V R GI+ T + + G R L+
Sbjct: 23 YENLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLY 82
Query: 244 RGNGINVLKIAPESAIKFMAYEQIKRLVGSDQ-ETLRIHERLVAGSLAGAIAQSSIYPME 302
+G N+ + F Y IK + E L E LV+ + AGA+ P+
Sbjct: 83 QGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEYLVSAAEAGAMTLCITNPLW 142
Query: 303 VLKTRMALRKTG-------QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLA 355
V KTR+ L+ QY GM D +I EGV YKG+VP + G + +
Sbjct: 143 VTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGT-SHGALQFM 201
Query: 356 VYETLKNAWLQHY-AVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGA 414
YE LK + QH + A ++ +S A+YP +VR R+Q Q
Sbjct: 202 AYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSG 261
Query: 415 PEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENL 460
+ + R EG G Y+G+APN ++V PA I++VVYEN+
Sbjct: 262 ----VIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENV 303
Score = 66.2 bits (160), Expect = 6e-11
Identities = 49/185 (26%), Positives = 90/185 (48%), Gaps = 13/185 (7%)
Query: 189 HLVAGGGAGAVSRTCTAPL--DRLKVLMQ----VHASRSNNMGIVGGFTQMIREGGARSL 242
+LV+ AGA++ T PL + ++++Q V++ G+ ++ + G R L
Sbjct: 123 YLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGL 182
Query: 243 WRGNGINVLKIAPESAIKFMAYEQIKRLVGSD-----QETLRIHERLVAGSLAGAIAQSS 297
++G + L A++FMAYE +K + L E + +L+ A ++
Sbjct: 183 YKGF-VPGLFGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAA 241
Query: 298 IYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVY 357
YP +V++ R+ + YSG++D + +EGV FYKG PN++ + P I VY
Sbjct: 242 TYPYQVVRARLQDQHMF-YSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVY 300
Query: 358 ETLKN 362
E + +
Sbjct: 301 ENVSH 305
Score = 32.3 bits (72), Expect = 0.95
Identities = 21/82 (25%), Positives = 34/82 (41%), Gaps = 1/82 (1%)
Query: 381 LACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVT-MSSLFKHILRTEGAFGLYRGL 439
L G LA +PL LV+ R +E P+ + I + +G GLY+G+
Sbjct: 26 LIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLYQGV 85
Query: 440 APNFMKVIPAVSISYVVYENLK 461
PN + + + Y +K
Sbjct: 86 TPNIWGAGLSWGLYFFFYNAIK 107
Score = 30.4 bits (67), Expect = 3.6
Identities = 11/47 (23%), Positives = 24/47 (51%)
Query: 225 GIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLV 271
G++ T+ R+ G ++G N++++ P I F+ YE + +
Sbjct: 261 GVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENVSHFL 307
>gi|55749577 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 4 [Homo
sapiens]
Length = 298
Score = 113 bits (282), Expect = 4e-25
Identities = 84/292 (28%), Positives = 144/292 (49%), Gaps = 24/292 (8%)
Query: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQV-HASRSNNM-----GIVGGFTQMIREGGARS 241
+ +AGG A AVS+T AP++R+K+L+QV HAS+ + GI+ ++ +E G S
Sbjct: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLS 69
Query: 242 LWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSL-----AGAIAQS 296
WRGN NV++ P A+ F ++ K+L + + R AG+L AGA +
Sbjct: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC 129
Query: 297 SIYPMEVLKTRMAL-----RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
+YP++ +TR+A ++ G+ DC +I +G+ Y+G+ ++ GII Y
Sbjct: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189
Query: 352 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 411
VY+T K V+ +FV + L SYP VR RM Q+
Sbjct: 190 AYFGVYDTAKGMLPDPKNVH-----IFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGR 244
Query: 412 EGAPEVTMSSL--FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
+GA + ++ ++ I + EGA ++G N ++ + + V+Y+ +K
Sbjct: 245 KGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFV-LVLYDEIK 295
>gi|157388989 solute carrier family 25, member 36 isoform a [Homo
sapiens]
Length = 311
Score = 108 bits (271), Expect = 8e-24
Identities = 85/303 (28%), Positives = 142/303 (46%), Gaps = 41/303 (13%)
Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQ------------------VHASRSNNMGIVGGF 230
HL AGG G V T PL+ +K +Q +R + G +
Sbjct: 9 HLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCL 68
Query: 231 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAGS 288
++ + G RSL+RG G N++ +AP AI F AY K + D ++ ++H +++ +
Sbjct: 69 KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVH--MISAA 126
Query: 289 LAGAIAQSSIYPMEVLKTRMAL--RKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLG 345
+AG A ++ P+ ++KTR+ L R G+ G +C R++ +G+ FY+G + G
Sbjct: 127 MAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAG 186
Query: 346 IIPYAGIDLAVYETLKNAWLQH----------YAVNSADPGVFVLLACGTMSSTCGQLAS 395
I I +YE++K L++ +V A V ++LA T S TC +
Sbjct: 187 ISETV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAAT-SKTCATTIA 244
Query: 396 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 455
YP +VRTR++ EG + +++ EG LYRGL + ++ IP +I
Sbjct: 245 YPHEVVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA 300
Query: 456 VYE 458
YE
Sbjct: 301 TYE 303
Score = 46.2 bits (108), Expect = 6e-05
Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 16/99 (16%)
Query: 379 VLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSL---------------- 422
V L G T G + + PL +V+TR+Q+ + EV ++++
Sbjct: 8 VHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHC 67
Query: 423 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
K IL EG L+RGL PN + V P+ +I + Y N K
Sbjct: 68 LKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCK 106
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 106 bits (264), Expect = 5e-23
Identities = 89/298 (29%), Positives = 140/298 (46%), Gaps = 20/298 (6%)
Query: 177 TVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHA----SRSNNMGIVGGFTQ 232
TV +G+ W+ V GG A V+ T P+D K +QV +R + G F
Sbjct: 31 TVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHA 90
Query: 233 MIR---EGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAG 287
+ R E G +L+ G +L+ A IK Y+ +KRL + ETL I+ ++ G
Sbjct: 91 LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLIN--MICG 148
Query: 288 SLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGII 347
++G I+ + P +VLK RM + + M+ I +EG ++G VP
Sbjct: 149 VVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAA 208
Query: 348 PYAGIDLAVYETLKNAWLQHYAVNSADPGVFV-LLACGTMSSTCGQLASYPLALVRTRMQ 406
G++L VY+ K + + FV CG G LAS P+ +VRTRM
Sbjct: 209 IVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMM 264
Query: 407 AQASIEGAPEV---TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Q +I G ++ T+ + K + + EG F LY+G PN++++ P I ++ YE LK
Sbjct: 265 NQRAIVGHVDLYKGTVDGILK-MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321
Score = 37.7 bits (86), Expect = 0.023
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM----GIVGGFTQMIREGGARSLWR 244
H V+ G + P+D ++ M + ++ G V G +M + G +L++
Sbjct: 238 HFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYK 297
Query: 245 GNGINVLKIAPESAIKFMAYEQIKRL 270
G N L++ P + I F+ YEQ+KRL
Sbjct: 298 GFWPNWLRLGPWNIIFFITYEQLKRL 323
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 106 bits (264), Expect = 5e-23
Identities = 89/298 (29%), Positives = 140/298 (46%), Gaps = 20/298 (6%)
Query: 177 TVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHA----SRSNNMGIVGGFTQ 232
TV +G+ W+ V GG A V+ T P+D K +QV +R + G F
Sbjct: 28 TVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHA 87
Query: 233 MIR---EGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAG 287
+ R E G +L+ G +L+ A IK Y+ +KRL + ETL I+ ++ G
Sbjct: 88 LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLIN--MICG 145
Query: 288 SLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGII 347
++G I+ + P +VLK RM + + M+ I +EG ++G VP
Sbjct: 146 VVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAA 205
Query: 348 PYAGIDLAVYETLKNAWLQHYAVNSADPGVFV-LLACGTMSSTCGQLASYPLALVRTRMQ 406
G++L VY+ K + + FV CG G LAS P+ +VRTRM
Sbjct: 206 IVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMM 261
Query: 407 AQASIEGAPEV---TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Q +I G ++ T+ + K + + EG F LY+G PN++++ P I ++ YE LK
Sbjct: 262 NQRAIVGHVDLYKGTVDGILK-MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 318
Score = 37.7 bits (86), Expect = 0.023
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM----GIVGGFTQMIREGGARSLWR 244
H V+ G + P+D ++ M + ++ G V G +M + G +L++
Sbjct: 235 HFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYK 294
Query: 245 GNGINVLKIAPESAIKFMAYEQIKRL 270
G N L++ P + I F+ YEQ+KRL
Sbjct: 295 GFWPNWLRLGPWNIIFFITYEQLKRL 320
>gi|157388991 solute carrier family 25, member 36 isoform b [Homo
sapiens]
Length = 310
Score = 105 bits (261), Expect = 1e-22
Identities = 85/303 (28%), Positives = 142/303 (46%), Gaps = 42/303 (13%)
Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQ------------------VHASRSNNMGIVGGF 230
HL AGG G V T PL+ +K +Q +R + G +
Sbjct: 9 HLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCL 68
Query: 231 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS--DQETLRIHERLVAGS 288
++ + G RSL+RG G N++ +AP AI F AY K + D ++ ++H +++ +
Sbjct: 69 KVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVH--MISAA 126
Query: 289 LAGAIAQSSIYPMEVLKTRMAL--RKTGQ-YSGMLDCARRILAREGVAAFYKGYVPNMLG 345
+AG A ++ P+ ++KTR+ L R G+ G +C R++ +G+ FY+G + G
Sbjct: 127 MAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAG 186
Query: 346 IIPYAGIDLAVYETLKNAWLQH----------YAVNSADPGVFVLLACGTMSSTCGQLAS 395
I I +YE++K L++ +V A V ++LA T S TC +
Sbjct: 187 ISETV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAAT-SKTCATTIA 244
Query: 396 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 455
YP +VRTR++ EG + +++ EG LYRGL + ++ IP +I
Sbjct: 245 YP-HVVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA 299
Query: 456 VYE 458
YE
Sbjct: 300 TYE 302
Score = 46.2 bits (108), Expect = 6e-05
Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 16/99 (16%)
Query: 379 VLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSL---------------- 422
V L G T G + + PL +V+TR+Q+ + EV ++++
Sbjct: 8 VHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHC 67
Query: 423 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
K IL EG L+RGL PN + V P+ +I + Y N K
Sbjct: 68 LKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCK 106
>gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens]
Length = 321
Score = 102 bits (253), Expect = 1e-21
Identities = 88/303 (29%), Positives = 133/303 (43%), Gaps = 39/303 (12%)
Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQ-------------VHASRSNNMGIVG------G 229
HL AGG G V T PL+ +K +Q VH + G+V G
Sbjct: 14 HLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPG 73
Query: 230 FTQMIR----EGGARSLWRGNGINVLKIAPESAIKFMAYEQIK-RLVGSDQETLRIHERL 284
Q+++ + G +SL+RG G N++ +AP A+ F Y + K + G I
Sbjct: 74 LFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIF 133
Query: 285 VAGSLAGAIAQSSIYPMEVLKTRMALR---KTGQYSGMLDCARRILAREGVAAFYKGYVP 341
AGS A I S + P+ ++KTRM L + + L CAR + EG+ FY+G
Sbjct: 134 SAGS-AAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTA 192
Query: 342 NMLGIIPYAGIDLAVYETLKNAWLQHYAVNSAD------PGVFVLLACGTMSSTCGQLAS 395
+ GI I A+YE+LK + +SA+ F L+A +S C +
Sbjct: 193 SYAGISETI-ICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIA 251
Query: 396 YPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 455
YP ++RTR++ EG + + + R EG YRGL ++ IP +I
Sbjct: 252 YPHEVIRTRLRE----EGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
Query: 456 VYE 458
YE
Sbjct: 308 TYE 310
Score = 79.0 bits (193), Expect = 9e-15
Identities = 52/214 (24%), Positives = 96/214 (44%), Gaps = 31/214 (14%)
Query: 272 GSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMA---------------------- 309
G +E +H L AG G + P+EV+KTR+
Sbjct: 5 GQQKENTLLH--LFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGA 62
Query: 310 --LRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQH 367
+R T G+ + IL +EG + ++G PN++G+ P + A Y K +
Sbjct: 63 GMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGI 122
Query: 368 YAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHIL 427
+ NS + + + G+ + L + P+ +V+TRMQ + + G+ ++ +++
Sbjct: 123 FVPNS---NIVHIFSAGSAAFITNSLMN-PIWMVKTRMQLEQKVRGSKQMNTLQCARYVY 178
Query: 428 RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
+TEG G YRGL ++ + + I + +YE+LK
Sbjct: 179 QTEGIRGFYRGLTASYAGISETI-ICFAIYESLK 211
Score = 62.4 bits (150), Expect = 9e-10
Identities = 48/185 (25%), Positives = 84/185 (45%), Gaps = 16/185 (8%)
Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS--RSNNMGIVGGFTQMIREGGARSLWRGN 246
H+ + G A ++ + P+ +K MQ+ S M + + + G R +RG
Sbjct: 131 HIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGL 190
Query: 247 GINVLKIAPESAIKFMAYEQIKRLV----------GSDQETLRIHERLVAGSLAGAIAQS 296
+ I+ E+ I F YE +K+ + G+++ + + A +L+ A
Sbjct: 191 TASYAGIS-ETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASC 249
Query: 297 SIYPMEVLKTRMALRKTG-QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLA 355
YP EV++TR LR+ G +Y + AR + EG AFY+G ++ IP I L+
Sbjct: 250 IAYPHEVIRTR--LREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLS 307
Query: 356 VYETL 360
YE +
Sbjct: 308 TYELI 312
>gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
Length = 291
Score = 99.8 bits (247), Expect = 5e-21
Identities = 79/286 (27%), Positives = 126/286 (44%), Gaps = 15/286 (5%)
Query: 187 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM-------GIVGGFTQMIREGGA 239
W+ V GG A + T P+D K +Q+ ++ G++ ++ RE G
Sbjct: 6 WKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGL 65
Query: 240 RSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIY 299
++L+ G +L+ A IK Y+ +KRL E + ++ G L+G I+ +
Sbjct: 66 KALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN 125
Query: 300 PMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYE- 358
P +VLK RM + GM+ I +EG +KG G++L VY+
Sbjct: 126 PTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDI 185
Query: 359 TLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVT 418
T K+ L ++ CG G LAS P+ +VRTRM Q +
Sbjct: 186 TKKHLILSGLMGDTVYTHFLSSFTCG----LAGALASNPVDVVRTRMMNQRVLRDGRCSG 241
Query: 419 MSSLFKHILRT---EGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
+ +L+T EG F LY+G PN++++ P I +V YE LK
Sbjct: 242 YTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLK 287
Score = 30.4 bits (67), Expect = 3.6
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 9/91 (9%)
Query: 187 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFT-------QMIREGGA 239
+ H ++ G + P+D ++ M R G G+T Q + G
Sbjct: 201 YTHFLSSFTCGLAGALASNPVDVVRTRMM--NQRVLRDGRCSGYTGTLDCLLQTWKNEGF 258
Query: 240 RSLWRGNGINVLKIAPESAIKFMAYEQIKRL 270
+L++G N L++ P + I F+ YEQ+K+L
Sbjct: 259 FALYKGFWPNWLRLGPWNIIFFVTYEQLKKL 289
>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
Length = 338
Score = 93.2 bits (230), Expect = 5e-19
Identities = 73/288 (25%), Positives = 131/288 (45%), Gaps = 20/288 (6%)
Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHAS--RSNNMGIVGGFTQMIREGGARSLWRGN 246
H+ AG AG + + P+D +K MQ + ++ I G +++R G RG
Sbjct: 48 HMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGV 107
Query: 247 GINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERL---VAGSLAGAIAQSSIYPMEV 303
+ ++ P A+ F YE +KR + +D + + L +AGS+A + + + P EV
Sbjct: 108 NVMIMGAGPAHAMYFACYENMKRTL-NDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEV 166
Query: 304 LKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNA 363
+K R+ + + Q+ + C R + EG+ AFY+ Y + IP+ I YE L+
Sbjct: 167 VKQRLQMYNS-QHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQ 225
Query: 364 WLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQ-------ASIEGAPE 416
H N + G ++ A+ PL + +T + Q A+I G
Sbjct: 226 VNPHRTYNPQSH-----IISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLS 280
Query: 417 VTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 464
M++ F+ + + G G ++G+ + +P+ +IS+ VYE K L
Sbjct: 281 -GMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327
Score = 58.2 bits (139), Expect = 2e-08
Identities = 46/188 (24%), Positives = 82/188 (43%), Gaps = 15/188 (7%)
Query: 280 IHERLVAGSLAGAIAQSSIYPMEVLKTRM---ALRKTGQYSGMLDCARRILAREGVAAFY 336
+ + AG++AG + S +YP++ +KTRM + QY+ + ++I+ EG
Sbjct: 45 VSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPL 104
Query: 337 KGYVPNMLGIIPYAGIDLAVYETLK---NAWLQHYAVNSADPGVFVLLACGTMSSTCGQL 393
+G ++G P + A YE +K N H + G+ G+M++
Sbjct: 105 RGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGI-----AGSMATLLHDA 159
Query: 394 ASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSIS 453
P +V+ R+Q + + + S + + RTEG YR IP SI
Sbjct: 160 VMNPAEVVKQRLQ----MYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIH 215
Query: 454 YVVYENLK 461
++ YE L+
Sbjct: 216 FITYEFLQ 223
>gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo
sapiens]
Length = 314
Score = 92.8 bits (229), Expect = 6e-19
Identities = 71/299 (23%), Positives = 129/299 (43%), Gaps = 34/299 (11%)
Query: 187 WRHL------VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 240
W HL V G + R P ++ +QV +S G F +++R G
Sbjct: 12 WEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGIT 71
Query: 241 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 300
L+RG +N + YE ++ V ++ + + LVAG A +AQS P
Sbjct: 72 GLYRGFLVNTFTLISGQCY-VTTYELTRKFVADYSQSNTV-KSLVAGGSASLVAQSITVP 129
Query: 301 MEVLKTRMALRKTGQYSGML------------------DCARRILAREGVAAFYKGYVPN 342
++V+ + +++ G+ G D R+IL +G+ FY+GYV +
Sbjct: 130 IDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVAS 189
Query: 343 MLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVR 402
+L IP + + Y A Y P + G +++ + + P+ ++R
Sbjct: 190 LLTYIPNSAVWWPFYHFY--AEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIR 247
Query: 403 TRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
TR+Q +EG + ++ F+ ++ EG +GL +GL+ + P+ + V YE+LK
Sbjct: 248 TRVQ----VEGKNSIILT--FRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 300
Score = 59.3 bits (142), Expect = 7e-09
Identities = 56/206 (27%), Positives = 95/206 (46%), Gaps = 26/206 (12%)
Query: 188 RHLVAGGGAGAVSRTCTAPLDRLK--VLMQVHASRSNNMGIVGG---------------F 230
+ LVAGG A V+++ T P+D + ++MQ + + G
Sbjct: 111 KSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDII 170
Query: 231 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAY----EQIKRLVGSDQETLRIHERLVA 286
Q+++ G R +RG ++L P SA+ + Y EQ+ L +E I + V+
Sbjct: 171 RQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLC--PKECPHIVFQAVS 228
Query: 287 GSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGI 346
G LA A A PM+V++TR+ + G+ S +L R+++A EG KG ++
Sbjct: 229 GPLAAATASILTNPMDVIRTRVQVE--GKNSIILTF-RQLMAEEGPWGLMKGLSARIISA 285
Query: 347 IPYAGIDLAVYETLKNAWLQHYAVNS 372
P + + YE+LK L+ V+S
Sbjct: 286 TPSTIVIVVGYESLKKLSLRPELVDS 311
>gi|149274643 solute carrier family 25, member 28 [Homo sapiens]
Length = 364
Score = 92.0 bits (227), Expect = 1e-18
Identities = 77/289 (26%), Positives = 126/289 (43%), Gaps = 29/289 (10%)
Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQV----HASRSNNMGIVGGFTQMIREGGARSLWR 244
H+VAG AG + P+D +K MQ A+R N ++ ++IR G R
Sbjct: 75 HMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRN--VLEALWRIIRTEGLWRPMR 132
Query: 245 GNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIH---ERLVAGSLAGAIA----QSS 297
G + P A+ F YE++K+ + IH +A AG +A ++
Sbjct: 133 GLNVTATGAGPAHALYFACYEKLKKTLSDV-----IHPGGNSHIANGAAGCVATLLHDAA 187
Query: 298 IYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVY 357
+ P EV+K RM + + Y + DC R + EG AFY+ Y + +P+ I Y
Sbjct: 188 MNPAEVVKQRMQMYNS-PYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTY 246
Query: 358 ETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEV 417
E L+ + N P VL G + A+ PL + +T + Q S+ +
Sbjct: 247 EFLQEHFNPQRRYN---PSSHVL--SGACAGAVAAAATTPLDVCKTLLNTQESLALNSHI 301
Query: 418 T-----MSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
T M+S F+ + + G +RG+ + IP+ +I++ VYE K
Sbjct: 302 TGHITGMASAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFK 350
Score = 57.8 bits (138), Expect = 2e-08
Identities = 51/205 (24%), Positives = 85/205 (41%), Gaps = 13/205 (6%)
Query: 272 GSDQETL----RIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRK---TGQYSGMLDCAR 324
G D E L + +VAG++AG + +YP++ +KTRM + +Y +L+
Sbjct: 60 GPDYEALPAGATVTTHMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALW 119
Query: 325 RILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACG 384
RI+ EG+ +G G P + A YE LK ++ A G
Sbjct: 120 RIIRTEGLWRPMRGLNVTATGAGPAHALYFACYEKLKKTLSD--VIHPGGNSHIANGAAG 177
Query: 385 TMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFM 444
+++ A P +V+ RMQ S P ++ + + + EGA YR
Sbjct: 178 CVATLLHDAAMNPAEVVKQRMQMYNS----PYHRVTDCVRAVWQNEGAGAFYRSYTTQLT 233
Query: 445 KVIPAVSISYVVYENLKITLGVQSR 469
+P +I ++ YE L+ Q R
Sbjct: 234 MNVPFQAIHFMTYEFLQEHFNPQRR 258
Score = 50.1 bits (118), Expect = 4e-06
Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 189 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMI-------REGGARS 241
H+++G AGAV+ T PLD K L+ S + N I G T M + GG +
Sbjct: 264 HVLSGACAGAVAAAATTPLDVCKTLLNTQESLALNSHITGHITGMASAFRTVYQVGGVTA 323
Query: 242 LWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLR 279
+RG V+ P +AI + YE K L+ QE R
Sbjct: 324 YFRGVQARVIYQIPSTAIAWSVYEFFKYLITKRQEEWR 361
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,101,994
Number of Sequences: 37866
Number of extensions: 674281
Number of successful extensions: 2740
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 124
Number of HSP's successfully gapped in prelim test: 77
Number of HSP's that attempted gapping in prelim test: 1794
Number of HSP's gapped (non-prelim): 542
length of query: 469
length of database: 18,247,518
effective HSP length: 106
effective length of query: 363
effective length of database: 14,233,722
effective search space: 5166841086
effective search space used: 5166841086
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.