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Search of human proteins with 119226217
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|119226217 membrane-spanning 4-domains, subfamily A, member
14 isoform 1 [Homo sapiens]
(679 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|119226217 membrane-spanning 4-domains, subfamily A, member 14... 1345 0.0
gi|119226220 membrane-spanning 4-domains, subfamily A, member 14... 1302 0.0
gi|20070328 membrane-spanning 4-domains, subfamily A, member 4 i... 71 3e-12
gi|23110995 membrane-spanning 4-domains, subfamily A, member 4 i... 71 3e-12
gi|44890059 involucrin [Homo sapiens] 71 4e-12
gi|214831008 membrane-spanning 4-domains, subfamily A, member 2 ... 70 8e-12
gi|8923206 membrane-spanning 4-domains, subfamily A, member 12 [... 70 8e-12
gi|4503677 membrane-spanning 4-domains, subfamily A, member 2 is... 69 2e-11
gi|23110997 membrane-spanning 4-domains, subfamily A, member 5 [... 65 2e-10
gi|221139761 zinc finger protein 853 [Homo sapiens] 64 4e-10
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 63 8e-10
gi|149588599 membrane-spanning 4-domains, subfamily A, member 15... 63 8e-10
gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A... 62 2e-09
gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A... 62 2e-09
gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A... 62 2e-09
gi|148746195 trichohyalin [Homo sapiens] 60 5e-09
gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B ... 58 3e-08
gi|73486649 membrane-spanning 4-domains, subfamily A, member 3 i... 56 1e-07
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 56 1e-07
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 56 1e-07
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 56 1e-07
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 56 1e-07
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 54 4e-07
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 54 4e-07
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 54 4e-07
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora... 53 1e-06
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 52 1e-06
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 52 1e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 52 2e-06
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 51 4e-06
>gi|119226217 membrane-spanning 4-domains, subfamily A, member 14
isoform 1 [Homo sapiens]
Length = 679
Score = 1345 bits (3480), Expect = 0.0
Identities = 679/679 (100%), Positives = 679/679 (100%)
Query: 1 MESTSQDRRATHVITIKPNETVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFG 60
MESTSQDRRATHVITIKPNETVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFG
Sbjct: 1 MESTSQDRRATHVITIKPNETVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFG 60
Query: 61 TIFALNYIGFSQRLPLVVLTGYPFWGALIFILTGYLTVTDKKSKLLGQGVTGMNVISSLV 120
TIFALNYIGFSQRLPLVVLTGYPFWGALIFILTGYLTVTDKKSKLLGQGVTGMNVISSLV
Sbjct: 61 TIFALNYIGFSQRLPLVVLTGYPFWGALIFILTGYLTVTDKKSKLLGQGVTGMNVISSLV 120
Query: 121 AITGITFTILSYRHQDKYCQMPSFEEICVFSRTLFIVLFFLPSDVTQNSEQPAPEENDQL 180
AITGITFTILSYRHQDKYCQMPSFEEICVFSRTLFIVLFFLPSDVTQNSEQPAPEENDQL
Sbjct: 121 AITGITFTILSYRHQDKYCQMPSFEEICVFSRTLFIVLFFLPSDVTQNSEQPAPEENDQL 180
Query: 181 QFVLQEEFSSDDSTTNAQSVIFGGYAFFKLTLSRSPLVSQPGNKGREFVPDEQKQSILPS 240
QFVLQEEFSSDDSTTNAQSVIFGGYAFFKLTLSRSPLVSQPGNKGREFVPDEQKQSILPS
Sbjct: 181 QFVLQEEFSSDDSTTNAQSVIFGGYAFFKLTLSRSPLVSQPGNKGREFVPDEQKQSILPS 240
Query: 241 PKFSEEEIEPLPPTLEKKPSENMSIQLDSTFKQMKDEDLQSAIVQPSQMQTKLLQDQAAS 300
PKFSEEEIEPLPPTLEKKPSENMSIQLDSTFKQMKDEDLQSAIVQPSQMQTKLLQDQAAS
Sbjct: 241 PKFSEEEIEPLPPTLEKKPSENMSIQLDSTFKQMKDEDLQSAIVQPSQMQTKLLQDQAAS 300
Query: 301 LQVFPSHSALKLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGI 360
LQVFPSHSALKLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGI
Sbjct: 301 LQVFPSHSALKLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGI 360
Query: 361 LSQDTSSQDMLFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEAS 420
LSQDTSSQDMLFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEAS
Sbjct: 361 LSQDTSSQDMLFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEAS 420
Query: 421 TSHIVQFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRR 480
TSHIVQFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRR
Sbjct: 421 TSHIVQFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRR 480
Query: 481 KSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDW 540
KSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDW
Sbjct: 481 KSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDW 540
Query: 541 LSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQ 600
LSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQ
Sbjct: 541 LSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQ 600
Query: 601 TQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGN 660
TQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGN
Sbjct: 601 TQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGN 660
Query: 661 LQAGQPRTVNLLAKNPLTG 679
LQAGQPRTVNLLAKNPLTG
Sbjct: 661 LQAGQPRTVNLLAKNPLTG 679
>gi|119226220 membrane-spanning 4-domains, subfamily A, member 14
isoform 2 [Homo sapiens]
Length = 662
Score = 1302 bits (3369), Expect = 0.0
Identities = 662/679 (97%), Positives = 662/679 (97%), Gaps = 17/679 (2%)
Query: 1 MESTSQDRRATHVITIKPNETVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFG 60
MESTSQDRRATHVITIKPNETVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFG
Sbjct: 1 MESTSQDRRATHVITIKPNETVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFG 60
Query: 61 TIFALNYIGFSQRLPLVVLTGYPFWGALIFILTGYLTVTDKKSKLLGQGVTGMNVISSLV 120
TIFALNYIGFSQRLPLVVLTGYPFWGALI GQGVTGMNVISSLV
Sbjct: 61 TIFALNYIGFSQRLPLVVLTGYPFWGALI-----------------GQGVTGMNVISSLV 103
Query: 121 AITGITFTILSYRHQDKYCQMPSFEEICVFSRTLFIVLFFLPSDVTQNSEQPAPEENDQL 180
AITGITFTILSYRHQDKYCQMPSFEEICVFSRTLFIVLFFLPSDVTQNSEQPAPEENDQL
Sbjct: 104 AITGITFTILSYRHQDKYCQMPSFEEICVFSRTLFIVLFFLPSDVTQNSEQPAPEENDQL 163
Query: 181 QFVLQEEFSSDDSTTNAQSVIFGGYAFFKLTLSRSPLVSQPGNKGREFVPDEQKQSILPS 240
QFVLQEEFSSDDSTTNAQSVIFGGYAFFKLTLSRSPLVSQPGNKGREFVPDEQKQSILPS
Sbjct: 164 QFVLQEEFSSDDSTTNAQSVIFGGYAFFKLTLSRSPLVSQPGNKGREFVPDEQKQSILPS 223
Query: 241 PKFSEEEIEPLPPTLEKKPSENMSIQLDSTFKQMKDEDLQSAIVQPSQMQTKLLQDQAAS 300
PKFSEEEIEPLPPTLEKKPSENMSIQLDSTFKQMKDEDLQSAIVQPSQMQTKLLQDQAAS
Sbjct: 224 PKFSEEEIEPLPPTLEKKPSENMSIQLDSTFKQMKDEDLQSAIVQPSQMQTKLLQDQAAS 283
Query: 301 LQVFPSHSALKLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGI 360
LQVFPSHSALKLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGI
Sbjct: 284 LQVFPSHSALKLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGI 343
Query: 361 LSQDTSSQDMLFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEAS 420
LSQDTSSQDMLFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEAS
Sbjct: 344 LSQDTSSQDMLFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEAS 403
Query: 421 TSHIVQFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRR 480
TSHIVQFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRR
Sbjct: 404 TSHIVQFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRR 463
Query: 481 KSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDW 540
KSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDW
Sbjct: 464 KSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDW 523
Query: 541 LSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQ 600
LSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQ
Sbjct: 524 LSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQ 583
Query: 601 TQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGN 660
TQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGN
Sbjct: 584 TQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGN 643
Query: 661 LQAGQPRTVNLLAKNPLTG 679
LQAGQPRTVNLLAKNPLTG
Sbjct: 644 LQAGQPRTVNLLAKNPLTG 662
>gi|20070328 membrane-spanning 4-domains, subfamily A, member 4
isoform a [Homo sapiens]
Length = 220
Score = 71.2 bits (173), Expect = 3e-12
Identities = 41/108 (37%), Positives = 61/108 (56%), Gaps = 5/108 (4%)
Query: 37 FLKGEPRVLGATQILLALIIVGFGTIFALNYIGFSQRLPLVVLTGYPFWGALIFILTGYL 96
FLKGEP+VLG QIL AL+ + G P+ V GY WG+++FI++G L
Sbjct: 39 FLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSL 98
Query: 97 TVTD--KKSKLLGQGVTGMNVISSLVAITGI---TFTILSYRHQDKYC 139
++ + +K L +G GMN+ SS++A +GI TF++ Y YC
Sbjct: 99 SIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYC 146
>gi|23110995 membrane-spanning 4-domains, subfamily A, member 4
isoform b [Homo sapiens]
Length = 239
Score = 71.2 bits (173), Expect = 3e-12
Identities = 41/108 (37%), Positives = 61/108 (56%), Gaps = 5/108 (4%)
Query: 37 FLKGEPRVLGATQILLALIIVGFGTIFALNYIGFSQRLPLVVLTGYPFWGALIFILTGYL 96
FLKGEP+VLG QIL AL+ + G P+ V GY WG+++FI++G L
Sbjct: 58 FLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSL 117
Query: 97 TVTD--KKSKLLGQGVTGMNVISSLVAITGI---TFTILSYRHQDKYC 139
++ + +K L +G GMN+ SS++A +GI TF++ Y YC
Sbjct: 118 SIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYC 165
>gi|44890059 involucrin [Homo sapiens]
Length = 585
Score = 70.9 bits (172), Expect = 4e-12
Identities = 112/488 (22%), Positives = 199/488 (40%), Gaps = 59/488 (12%)
Query: 210 LTLSRSPLVSQPGNKGREFVPDEQKQSILPSPKFSEEEIE---PLPPTLEKKPSENMSIQ 266
L ++ SP +SQ E +++ P +E+++ PLPP +K P E + ++
Sbjct: 7 LPVTLSPALSQ-----------ELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVE-LPVE 54
Query: 267 LDSTFKQMKDEDLQSAIVQPSQMQTKLLQDQAASLQVFPSHSALKLEDISPEDLPSQALP 326
+ S ++ ++ Q + Q K Q+Q Q + H E+ + P Q L
Sbjct: 55 VPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQH-----EEYQKAENPEQQLK 109
Query: 327 VEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTS---SQDMLFHDMTSQDMQSL 383
E+T + + +++ L L Q ++ +D ++ L ++ Q L
Sbjct: 110 ----QEKTQRDQQLNKQLEEEKKLLDQQLD-QELVKRDEQLGMKKEQLL-ELPEQQEGHL 163
Query: 384 DMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQFPEIQHLLQQPPDLQPE 443
L Q P Q Q L + LPE + + PE Q + P+ Q
Sbjct: 164 KHLEQQEGQLKHPEQQ-EGQLELPEQQEGQLELPEQQEGQL-ELPEQQEGQLELPEQQEG 221
Query: 444 NTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSL 503
E QQ Q+ + +E +++ + + EL ++ + L Q L+
Sbjct: 222 QLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMG 281
Query: 504 DVQAKGQKSSKRHSLDQQSKGWQSPKQ-----KSLDQQIKDWLSPKRHSVDKQAQLNQTK 558
++ Q+ + LDQQ K + P+Q K L+QQ +H ++ QL Q +
Sbjct: 282 QLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQE----GQPKHLEQQEGQLEQLE 337
Query: 559 EQ---LPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKK 615
EQ L + ++ Q + ++ EGQ G + Q +Q K+Q Q + E++ Q K
Sbjct: 338 EQEGQLKHLEQQEGQLEHLEHQEGQL--GLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKH 395
Query: 616 --SPKGQFQN-VQAEGQQAQVEKVPKLLCQDS------ESQIQQYQFWQFHKGNL----- 661
+GQ ++ VQ EGQ Q E+ + L Q E Q Q + + +G L
Sbjct: 396 LVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQ 455
Query: 662 QAGQPRTV 669
Q GQP+ +
Sbjct: 456 QVGQPKNL 463
Score = 62.0 bits (149), Expect = 2e-09
Identities = 98/430 (22%), Positives = 174/430 (40%), Gaps = 74/430 (17%)
Query: 232 EQKQSILPSPKFSEEEIEPLPPTLEKKPSENMSIQLDSTFKQMKDEDLQSAIVQPSQMQT 291
EQ++ L P+ E ++E + +++ +S Q + K ++ ++ Q + + Q
Sbjct: 227 EQQEGQLELPQQQEGQLEL---SEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQL 283
Query: 292 KLLQDQAASLQVFPSHSALKLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLT 351
K L+ Q L+ L ++ PE LP Q + G + + H++Q
Sbjct: 284 KYLEQQEGQLK------HLDQQEKQPE-LPEQQM---GQLKHLEQQEGQPKHLEQQ---- 329
Query: 352 ANDLPPQGILSQDTSSQDMLFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLS--QA 409
+G L Q + L H Q L+ L +P Q + L Q
Sbjct: 330 ------EGQLEQLEEQEGQLKH--LEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQG 381
Query: 410 LSAHAILPEASTSHIVQFP-EIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEET 468
H E H+VQ +++HL+QQ L E Q +Q+
Sbjct: 382 QPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQL-----EQQERQV---------------- 420
Query: 469 KEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSP 528
E L ++ +H L +Q L++L + ++ Q+ + +L+Q+ K + P
Sbjct: 421 ------EHLEQQVGQLKH-LEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELP 473
Query: 529 KQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKD 588
+Q+ + Q+K H ++AQL ++Q+ + +QQ K ++PE Q DGQ+K
Sbjct: 474 EQQ--EGQVK-------HLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQ--DGQLKH 522
Query: 589 QQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQI 648
+ + Q + Q Q E QP GQ Q++ Q A K LL + + Q
Sbjct: 523 LEQQEGQLKDLEQQKGQLE-QPV--FAPAPGQVQDI----QPALPTKGEVLLPVEHQQQK 575
Query: 649 QQYQFWQFHK 658
Q+ Q+ HK
Sbjct: 576 QEVQWPPKHK 585
Score = 45.1 bits (105), Expect = 2e-04
Identities = 84/429 (19%), Positives = 172/429 (40%), Gaps = 55/429 (12%)
Query: 245 EEEIEPLPPTLEK---KPSENMSIQLDSTFKQMKDEDLQSAIVQPSQMQTKLLQDQAASL 301
EEE + L L++ K E + ++ + + + ++ ++ + Q K + Q L
Sbjct: 124 EEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQL 183
Query: 302 QVFPSHSALKLEDISPEDLPSQA-LPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGI 360
++ P +LE PE Q LP + + +P + +LP Q
Sbjct: 184 EL-PEQQEGQLE--LPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQE 240
Query: 361 LSQDTSSQDMLFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQA------LSAHA 414
+ S Q +++ Q L L +P + + L Q L
Sbjct: 241 GQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQE 300
Query: 415 ILPEASTSHIVQFPEIQHLLQQPPDL-----QPENTEPQNQQILQMSYQDIRSEVMEETK 469
PE + Q ++ QP L Q E E Q Q+ + Q+ + E +E +
Sbjct: 301 KQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQE 360
Query: 470 --------EWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQ 521
+ ++L +++ +H L ++ L++L VQ +GQ +H + Q+
Sbjct: 361 GQLGLPEQQVLQLKQLEKQQGQPKH-LEEEEGQLKHL------VQQEGQL---KHLVQQE 410
Query: 522 SKGWQSPKQ-KSLDQQIKDWLSPKRHSVDKQAQLNQTKEQ-----LPDQQA--------E 567
+ Q +Q + L+QQ+ +H +++ QL ++Q +P+QQ E
Sbjct: 411 GQLEQQERQVEHLEQQV----GQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQE 466
Query: 568 DQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNV-QA 626
++Q + + EGQ K + ++ Q + + Q + + +++ + + GQ +++ Q
Sbjct: 467 EKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQ 526
Query: 627 EGQQAQVEK 635
EGQ +E+
Sbjct: 527 EGQLKDLEQ 535
>gi|214831008 membrane-spanning 4-domains, subfamily A, member 2
isoform 2 [Homo sapiens]
Length = 195
Score = 69.7 bits (169), Expect = 8e-12
Identities = 51/162 (31%), Positives = 75/162 (46%), Gaps = 21/162 (12%)
Query: 10 ATHVITIKPNET----VLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFGTIFA- 64
A V+ I P E +L + P + L LK E LG TQIL A+I + FGT+
Sbjct: 22 AFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEFLGVTQILTAMICLCFGTVVCS 81
Query: 65 -LNYIGFSQRLPLVVLTGYPFWGALIFILTGYLTVTDKK--SKLLGQGVTGMNVISSLVA 121
L+ + GYPFWGA+ F ++G L++ ++ + L +G G N SS+
Sbjct: 82 VLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAG 141
Query: 122 ITGITFTILSYRHQDKY-------------CQMPSFEEICVF 150
TGIT I++ + Y C M SF +C+F
Sbjct: 142 GTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFSTVCIF 183
>gi|8923206 membrane-spanning 4-domains, subfamily A, member 12
[Homo sapiens]
Length = 267
Score = 69.7 bits (169), Expect = 8e-12
Identities = 37/97 (38%), Positives = 58/97 (59%), Gaps = 5/97 (5%)
Query: 39 KGEPRVLGATQILLALIIVGFGTIFALNYIGFSQRLPLV---VLTGYPFWGALIFILTGY 95
K E + LG QI++ L+ +GFG + L F + L V+ GYPFWG L FI++G
Sbjct: 85 KEEAKALGVIQIMVGLMHIGFGIVLCLISFSFREVLGFASTAVIGGYPFWGGLSFIISGS 144
Query: 96 LTVTDKK--SKLLGQGVTGMNVISSLVAITGITFTIL 130
L+V+ K S+ L +G GMN++SS++A G+ ++
Sbjct: 145 LSVSASKELSRCLVKGSLGMNIVSSILAFIGVILLLV 181
>gi|4503677 membrane-spanning 4-domains, subfamily A, member 2
isoform 1 [Homo sapiens]
Length = 244
Score = 68.6 bits (166), Expect = 2e-11
Identities = 53/167 (31%), Positives = 80/167 (47%), Gaps = 15/167 (8%)
Query: 10 ATHVITIKPNET----VLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFGTIFA- 64
A V+ I P E +L + P + L LK E LG TQIL A+I + FGT+
Sbjct: 22 AFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEFLGVTQILTAMICLCFGTVVCS 81
Query: 65 -LNYIGFSQRLPLVVLTGYPFWGALIFILTGYLTVTDKK--SKLLGQGVTGMNVISSLVA 121
L+ + GYPFWGA+ F ++G L++ ++ + L +G G N SS+
Sbjct: 82 VLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAG 141
Query: 122 ITGITFTILSYRHQDKYCQMPS----FEEICV---FSRTLFIVLFFL 161
TGIT I++ + Y + S FE C FS + +++ FL
Sbjct: 142 GTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFSTEIVVMMLFL 188
>gi|23110997 membrane-spanning 4-domains, subfamily A, member 5
[Homo sapiens]
Length = 200
Score = 65.5 bits (158), Expect = 2e-10
Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 14/155 (9%)
Query: 21 TVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFGTIFALNYIGFSQRLPLVVLT 80
T L+A + S L + ++LG QIL ++ FG IF + R P + L+
Sbjct: 26 TELSATTFSTQSPLQKLFARKMKILGTIQILFGIMTFSFGVIFLFTLLKPYPRFPFIFLS 85
Query: 81 GYPFWGALIFILTG--YLTVTDKKSKLLGQGVTGMNVISSLVAITGI---TF-------T 128
GYPFWG+++FI +G + V K ++ L MN +S+L AI GI TF
Sbjct: 86 GYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIMNFLSALGAIAGIILLTFGFILDQNY 145
Query: 129 ILSYRHQDKYCQMPS--FEEICVFSRTLFIVLFFL 161
I Y HQ+ C+ + F I + T I+ F+
Sbjct: 146 ICGYSHQNSQCKAVTVLFLGILITLMTFSIIELFI 180
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 64.3 bits (155), Expect = 4e-10
Identities = 63/233 (27%), Positives = 109/233 (46%), Gaps = 26/233 (11%)
Query: 435 QQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKA 494
Q+ + Q N+ PQ + S SE+ EET+ + E +L + + Q +
Sbjct: 52 QEEEEPQERNSSPQRPAV---SAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQ 108
Query: 495 LQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIK-----DWLSPKRHSVD 549
LQ + H L++Q + Q+ ++ Q + QS + L +++ L P++ V
Sbjct: 109 LQQPQPH-LELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQ--VQ 165
Query: 550 KQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQ 609
+Q +L Q +EQL QQA++QQ +Q + QV++QQ ++Q + Q Q + +
Sbjct: 166 EQQRLQQQQEQLQTQQAQEQQVLQQQ----EQLQQQVQEQQLLQQQQEQLQQQQLLQQQE 221
Query: 610 PAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGNLQ 662
Q++ QFQ Q + QQ Q +LL + Q+QQ Q Q + LQ
Sbjct: 222 QLQQQ-----QFQQQQEQLQQQQ-----QLLLLQQQGQLQQ-QLLQQQQAQLQ 263
Score = 62.4 bits (150), Expect = 1e-09
Identities = 62/238 (26%), Positives = 110/238 (46%), Gaps = 22/238 (9%)
Query: 429 EIQHLLQQPPDLQPENTEPQNQQILQ-MSYQDIRSEVMEETKEWKSEEELHRRKSSRRHS 487
++Q L QQP Q +PQ++Q+ Q + +++ + ++ ++ S+ + + +S
Sbjct: 90 QLQQLEQQPEPQQ----QPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQE 145
Query: 488 LNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHS 547
L + LQ + + Q + Q+ ++ L QQ + Q+ Q++ +QQ+ +
Sbjct: 146 LKPE---LQLMHQQQ---QLQPQQVQEQQRLQQQQEQLQT--QQAQEQQVLQQQEQLQQQ 197
Query: 548 VDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTE 607
V +Q L Q +EQL QQ QQ + +Q + Q + Q++ QQ + Q Q Q +
Sbjct: 198 VQEQQLLQQQQEQLQQQQLLQQQEQLQQ-QQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQ 256
Query: 608 DQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGNLQAGQ 665
Q A Q Q E QQAQ+++ L Q+ Q QQ Q Q + LQ Q
Sbjct: 257 QQQA--------QLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQ 306
Score = 60.8 bits (146), Expect = 4e-09
Identities = 72/292 (24%), Positives = 119/292 (40%), Gaps = 30/292 (10%)
Query: 361 LSQDTSSQDMLFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEAS 420
L Q Q H+ Q L++ Q P QD Q LSQ S
Sbjct: 94 LEQQPEPQQQPQHEQLQQPQPHLELQQQ-------PQQD--GQQQLSQLQQEK----HQS 140
Query: 421 TSHIVQFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRR 480
H PE+Q L+ Q LQP+ Q QQ LQ + ++++ +E + + +E+L ++
Sbjct: 141 VHHQELKPELQ-LMHQQQQLQPQQV--QEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQ 197
Query: 481 KSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDW 540
++ QQ + Q + + Q ++ L QQ + +Q L QQ+
Sbjct: 198 VQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQ- 256
Query: 541 LSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQ 600
+QAQL Q + L QQA+ QQ Q E + Q + Q +EQ ++Q
Sbjct: 257 --------QQQAQLQQ--QLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQ 306
Query: 601 TQDQQTEDQPAQE---KKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQ 649
Q E + +E + P + E Q+ ++E+ +L Q + Q+Q
Sbjct: 307 LQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQ 358
Score = 57.4 bits (137), Expect = 4e-08
Identities = 73/342 (21%), Positives = 146/342 (42%), Gaps = 30/342 (8%)
Query: 314 DISPEDLPSQA-LPVEGLSEQTMPSKSTSSHVKQSS--NLTANDLPPQGILSQDTSSQDM 370
+I+ E P Q L ++ L +Q P + Q +L P Q Q + Q
Sbjct: 77 EIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQE 136
Query: 371 LFHDMTSQDMQ-SLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQFPE 429
+ Q+++ L ++ Q + PQ + Q L Q + Q +
Sbjct: 137 KHQSVHHQELKPELQLMHQQ---QQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQ 193
Query: 430 IQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELH--RRKSSRRHS 487
+Q +Q+ LQ + + Q QQ+LQ Q + + ++ ++ + +++L +++ +
Sbjct: 194 LQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQ 253
Query: 488 LNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLS----- 542
L QQ +A L++ L+ Q Q ++ L QQ + Q +Q+ L QQ ++ L
Sbjct: 254 LLQQQQA--QLQQQLLEQQ---QAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQ 308
Query: 543 --PKRHSVDKQAQLNQT-----KEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQ 595
P +++ +L EQ +QQ ++ + + E + + + Q+K Q+ ++
Sbjct: 309 PPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQL 368
Query: 596 NSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVP 637
+ + Q QQ E Q Q + +P + A+ Q+ Q+E P
Sbjct: 369 EQQLEQQQQQLEQQEVQLELTP----VELGAQQQEVQLELTP 406
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 63.2 bits (152), Expect = 8e-10
Identities = 100/455 (21%), Positives = 201/455 (44%), Gaps = 57/455 (12%)
Query: 231 DEQKQSILPSPKFSEEEIEPLP----------------PTLEKKPSENMSIQLDSTFKQM 274
D + S+L P EP P P + + ++++S+ +S K+
Sbjct: 1149 DAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVSPEDTQSLSLSEESPSKET 1208
Query: 275 KDEDLQSAIVQPSQMQTKLLQDQAASLQVFPSHSALKLEDISPEDLPSQALPVEGLSEQT 334
D+ S + P + T LQ +L ++ ED S P ++P + +
Sbjct: 1209 S-LDVSSKQLSPESLGT--LQFGELNLGKEEMGHLMQAEDTSHHTAP-MSVPEPHAATAS 1264
Query: 335 MPSKSTSSHVKQSSNLTANDLP---PQGILSQDTSSQD--MLFHDMTSQDMQSLDMLSQD 389
P+ T+ + Q+ ++T + L P S T S + L +TS D +L+ D
Sbjct: 1265 PPTDGTTRYSAQT-DITDDSLDRKSPASSFSHSTPSGNGKYLPGAITSPDEH---ILTPD 1320
Query: 390 TPSHAMPPQDIPSQDMLSQALSAHAILP--EASTSHIVQFPEIQHLLQQPPDLQPEN--- 444
+ S + P+ +P + A+ +P + TS + PE + + Q D E+
Sbjct: 1321 S-SFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEV 1379
Query: 445 TEPQNQQILQMSYQ-DIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSL 503
EP++ I Q +++E +++ K+ E+ R + +L Q+ KAL+ +
Sbjct: 1380 VEPKDTAIYQKDEALHVKNEAVKQQD--KALEQKGRDLEQKDTALEQKDKALEPKDK--- 1434
Query: 504 DVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPD 563
D++ K + ++ + ++ K +L+Q+ K L PK ++++ ++ + KE++P+
Sbjct: 1435 DLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKA-LEPKDKDLEQKDRVLEQKEKIPE 1493
Query: 564 Q--QAEDQQAKGEQYPEGQSKDGQVKD---QQTDKEQNSKKQTQDQ-----QTEDQPAQE 613
+ +A DQ+ + ++ + ++KD +QTDK K Q Q+Q + +DQ ++
Sbjct: 1494 EKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQ 1553
Query: 614 KKSPKGQ-----FQNVQAEGQQAQVEKVPKLLCQD 643
K GQ QN+QA + Q ++ L+ +D
Sbjct: 1554 KYWALGQKDEALEQNIQALEENHQTQEQESLVQED 1588
Score = 30.8 bits (68), Expect = 4.3
Identities = 29/163 (17%), Positives = 67/163 (41%), Gaps = 2/163 (1%)
Query: 479 RRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIK 538
++++ + SL TK +V +G K ++ + +K + K+ S K
Sbjct: 314 KQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEK 373
Query: 539 DWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSK 598
P+R + L K +L + + K + + KD + K+ + ++++ K
Sbjct: 374 P-AKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKK 432
Query: 599 KQTQDQQTEDQPAQEK-KSPKGQFQNVQAEGQQAQVEKVPKLL 640
+ + ++ +D +EK K K + + + + +V K L
Sbjct: 433 DEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTL 475
>gi|149588599 membrane-spanning 4-domains, subfamily A, member 15
isoform 1 [Homo sapiens]
Length = 240
Score = 63.2 bits (152), Expect = 8e-10
Identities = 41/133 (30%), Positives = 65/133 (48%), Gaps = 25/133 (18%)
Query: 5 SQDRRATHVITIKPNETVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFGTIFA 64
+Q RAT ++P ET FL GEP+VLG QIL+ LI +GFG++
Sbjct: 49 AQTPRATQPPDLRPVET---------------FLTGEPKVLGTVQILIGLIHLGFGSVLL 93
Query: 65 L---NYIGFSQRLPLVVLTGYPFWGALIFILTGYLTVTDKK--SKLLGQGVTGMNVISSL 119
+ ++G + G PFWG FI++G L+V +K + L + G N++S +
Sbjct: 94 MVRRGHVGI-----FFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVM 148
Query: 120 VAITGITFTILSY 132
A G ++ +
Sbjct: 149 AAFAGTAILLMDF 161
>gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A,
member 4E isoform 1 [Homo sapiens]
Length = 243
Score = 62.0 bits (149), Expect = 2e-09
Identities = 37/125 (29%), Positives = 63/125 (50%), Gaps = 5/125 (4%)
Query: 37 FLKGEPRVLGATQILLALIIVGFGTIFALNYIGFSQRLPLVVLTGYPFWGALIFILTGYL 96
F K +P+VLG +IL+AL+ + G I + P+ V Y WG+++FI++ L
Sbjct: 62 FFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYVAYTIWGSVMFIISVSL 121
Query: 97 TVTD--KKSKLLGQGVTGMNVISSLVAITGITFTILS---YRHQDKYCQMPSFEEICVFS 151
+V + +K L G G N+ SS++AI+GI +S Y + YC C +
Sbjct: 122 SVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAISLTFYSFRYHYCNHDQLSSNCYMT 181
Query: 152 RTLFI 156
++ +
Sbjct: 182 MSILM 186
>gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A,
member 4E isoform 3 [Homo sapiens]
Length = 243
Score = 62.0 bits (149), Expect = 2e-09
Identities = 37/125 (29%), Positives = 63/125 (50%), Gaps = 5/125 (4%)
Query: 37 FLKGEPRVLGATQILLALIIVGFGTIFALNYIGFSQRLPLVVLTGYPFWGALIFILTGYL 96
F K +P+VLG +IL+AL+ + G I + P+ V Y WG+++FI++ L
Sbjct: 62 FFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYVAYTIWGSVMFIISVSL 121
Query: 97 TVTD--KKSKLLGQGVTGMNVISSLVAITGITFTILS---YRHQDKYCQMPSFEEICVFS 151
+V + +K L G G N+ SS++AI+GI +S Y + YC C +
Sbjct: 122 SVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAISLTFYSFRYHYCNHDQLSSNCYMT 181
Query: 152 RTLFI 156
++ +
Sbjct: 182 MSILM 186
>gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A,
member 4E isoform 3 [Homo sapiens]
Length = 243
Score = 62.0 bits (149), Expect = 2e-09
Identities = 37/125 (29%), Positives = 63/125 (50%), Gaps = 5/125 (4%)
Query: 37 FLKGEPRVLGATQILLALIIVGFGTIFALNYIGFSQRLPLVVLTGYPFWGALIFILTGYL 96
F K +P+VLG +IL+AL+ + G I + P+ V Y WG+++FI++ L
Sbjct: 62 FFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYVAYTIWGSVMFIISVSL 121
Query: 97 TVTD--KKSKLLGQGVTGMNVISSLVAITGITFTILS---YRHQDKYCQMPSFEEICVFS 151
+V + +K L G G N+ SS++AI+GI +S Y + YC C +
Sbjct: 122 SVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAISLTFYSFRYHYCNHDQLSSNCYMT 181
Query: 152 RTLFI 156
++ +
Sbjct: 182 MSILM 186
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 60.5 bits (145), Expect = 5e-09
Identities = 46/211 (21%), Positives = 105/211 (49%), Gaps = 14/211 (6%)
Query: 440 LQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLR 499
L+ E E + +Q L+ Q R + + ++ + E++L R + RR QQ + Q LR
Sbjct: 364 LRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE---QQLRREQQLR 420
Query: 500 RHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKE 559
R Q + ++ +RH + + + + K ++ +DWL KR ++ + + K+
Sbjct: 421 REQ---QLRREQEEERHEQKHEQER-REQRLKREQEERRDWL--KREEETERHEQERRKQ 474
Query: 560 QLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKG 619
QL Q E+++ + + E + ++ QQ +EQ +++ ++++ + QE++
Sbjct: 475 QLKRDQEEERRERWLKLEEEERRE-----QQERREQQLRREQEERREQRLKRQEEEERLQ 529
Query: 620 QFQNVQAEGQQAQVEKVPKLLCQDSESQIQQ 650
Q + + ++ Q E+ +LL ++ E +++Q
Sbjct: 530 QRLRSEQQLRREQEERREQLLKREEEKRLEQ 560
Score = 52.8 bits (125), Expect = 1e-06
Identities = 50/242 (20%), Positives = 113/242 (46%), Gaps = 18/242 (7%)
Query: 429 EIQHLLQQPPDLQPENTEPQ-NQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHS 487
E + L+Q D + E Q ++Q +++ +V + +E K EE + + R
Sbjct: 1403 EREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRK 1462
Query: 488 LNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHS 547
++ + LQ L Q + +K + ++Q Q +K +Q+++ P+R
Sbjct: 1463 FREEEQLLQEREEQQLHRQERDRKFLE----EEQQLRRQERDRKFREQELRSQ-EPERKF 1517
Query: 548 VDKQAQLNQTKEQ---LPDQQAEDQQAKGEQ--------YPEGQSKDGQVKDQQTDKEQN 596
++++ QL++ + Q L ++Q +Q +G+Q + E + + ++QQ +++
Sbjct: 1518 LEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQER 1577
Query: 597 SKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQF 656
+K ++Q + QE+K + + Q + EGQQ Q+ + ++ E +Q+ + Q
Sbjct: 1578 DRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQ-QLRQERDRKFREDEQLLQEREEQQL 1636
Query: 657 HK 658
H+
Sbjct: 1637 HR 1638
Score = 50.4 bits (119), Expect = 5e-06
Identities = 52/246 (21%), Positives = 109/246 (44%), Gaps = 8/246 (3%)
Query: 425 VQFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSR 484
+QF E + LQ+ Q E LQ + RS+ ++W+ + L + R
Sbjct: 831 LQFLEEEEQLQRRERAQQLQEEEDG---LQEDQERRRSQEQRRDQKWRWQ--LEEERKRR 885
Query: 485 RHSLNQQTKALQYLRRHS--LDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLS 542
RH+L + + LR+ L + + + +R +Q + Q +++ L Q+ + L
Sbjct: 886 RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLR 945
Query: 543 PKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQ 602
+R +Q + Q ++ QQ E +Q GE+ + + ++ + K ++ ++ Q ++Q
Sbjct: 946 EEREKRRRQERERQYRKDKKLQQKE-EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
Query: 603 DQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGNLQ 662
++ E + QE + + +Q E +Q E+ K Q+ E Q ++ + Q + L
Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLL 1064
Query: 663 AGQPRT 668
+ T
Sbjct: 1065 GEERET 1070
Score = 50.4 bits (119), Expect = 5e-06
Identities = 49/250 (19%), Positives = 110/250 (44%), Gaps = 31/250 (12%)
Query: 426 QFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQD-----------IRSEV----MEETKE 470
Q+ E + + Q+ L E E + +Q L+ Y++ +R E E ++
Sbjct: 1139 QYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQ 1198
Query: 471 WKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQ 530
++ EEEL R+K +R+ Q R L Q + +K + KG ++ +
Sbjct: 1199 YREEEELQRQKRKQRYRDEDQ--------RSDLKWQWEPEKENAVRDNKVYCKGRENEQF 1250
Query: 531 KSL-DQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQ 589
+ L D Q++D ++ D Q L + +E+ +Q+ Q + +PE + + +++
Sbjct: 1251 RQLEDSQLRD----RQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLE---REE 1303
Query: 590 QTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQ 649
Q + ++ +K +++Q + +EK+ + + + E Q Q + L Q+ + + +
Sbjct: 1304 QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFR 1363
Query: 650 QYQFWQFHKG 659
+ + +G
Sbjct: 1364 EEELRHQEQG 1373
Score = 50.1 bits (118), Expect = 7e-06
Identities = 53/264 (20%), Positives = 116/264 (43%), Gaps = 33/264 (12%)
Query: 429 EIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSL 488
E Q L ++ +LQ E E + +Q + Y++ E +++ +E EE +R+ R
Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQERQYRE--EEQLQQEEEQLLREEREKRRRQERERQ 959
Query: 489 NQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSV 548
++ K LQ + Q G++ KR +++ K + + + ++Q+ KR
Sbjct: 960 YRKDKKLQ-----QKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ 1014
Query: 549 D------KQAQLNQTKEQL--------------------PDQQAEDQQAKGEQYPEGQSK 582
+ K+ +L Q +EQL + Q E++Q GE+ + +
Sbjct: 1015 EWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQ 1074
Query: 583 DGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQ 642
+ + + ++ ++ Q ++Q ++ E + QE++ + + +Q E +Q E+ K Q
Sbjct: 1075 ELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ 1134
Query: 643 DSESQIQQYQFWQFHKGNLQAGQP 666
+ E Q ++ + Q + L +P
Sbjct: 1135 ELERQYREEEEVQQEEEQLLREEP 1158
Score = 49.7 bits (117), Expect = 9e-06
Identities = 48/229 (20%), Positives = 110/229 (48%), Gaps = 21/229 (9%)
Query: 429 EIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSL 488
E Q ++ + + + E + QQ+ + + ++ E +E + E++L R + R
Sbjct: 316 EQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERRE- 374
Query: 489 NQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSV 548
QQ + Q LRR + Q + ++ +R +QQ + Q Q +QQ++ +R
Sbjct: 375 -QQLRREQQLRR---EQQLRREQQLRR---EQQLRREQ---QLRREQQLRREQQLRREQQ 424
Query: 549 DKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQ---DQQ 605
++ Q + EQ +Q+ +Q+ K EQ + +D ++++T++ + +++ Q DQ+
Sbjct: 425 LRREQEEERHEQKHEQERREQRLKREQ---EERRDWLKREEETERHEQERRKQQLKRDQE 481
Query: 606 TEDQ----PAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQ 650
E + +E++ + Q + Q ++ + + +L Q+ E ++QQ
Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530
Score = 49.7 bits (117), Expect = 9e-06
Identities = 47/244 (19%), Positives = 117/244 (47%), Gaps = 24/244 (9%)
Query: 431 QHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQ 490
Q L ++ + + + + Q ++ + Q +RSE ++ + E+L +R+ +R +
Sbjct: 505 QQLRREQEERREQRLKRQEEE--ERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562
Query: 491 QTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDK 550
+ + L+ + D K ++ ++ L ++ +++ L+Q++ KR V++
Sbjct: 563 REQRLKREQEERRDQLLKREEERRQQRLKRE-------QEERLEQRL------KREEVER 609
Query: 551 QAQLNQTKEQL----PDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQT 606
Q + +++L P+++ Q K E+ E + + + ++QQ +EQ K++ ++++
Sbjct: 610 LEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLR-REQQERREQRLKREEEEERL 668
Query: 607 EDQPAQEKKSPKGQFQNVQAEGQQAQ---VEKVPKLLCQDSESQIQQYQFWQFHKGNLQA 663
E + +E + + + + + E +QA+ ++PK Q ES+ Q + + Q
Sbjct: 669 EQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQ-LESEADARQSKVYSRPRKQE 727
Query: 664 GQPR 667
GQ R
Sbjct: 728 GQRR 731
Score = 49.3 bits (116), Expect = 1e-05
Identities = 46/264 (17%), Positives = 116/264 (43%), Gaps = 39/264 (14%)
Query: 428 PEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRK------ 481
P + L ++P + + + Q +++ + Q + E +E+ + +EEL R++
Sbjct: 124 PRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQER 183
Query: 482 -----------SSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQ 530
S + H + Q RR L+++ KG++ ++ ++Q + +Q ++
Sbjct: 184 EERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEE 243
Query: 531 KSLDQQI----KDWLSPKRHSVDKQAQLNQTKEQL--------------PDQQAE----D 568
K ++ K+ + +Q +L + +EQL +QQ + +
Sbjct: 244 KEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE 303
Query: 569 QQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEG 628
QQ + +Q E + + + ++QQ +EQ +++ Q + E + +E++ + Q + + +
Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQ 363
Query: 629 QQAQVEKVPKLLCQDSESQIQQYQ 652
+ + E+ + E Q+++ Q
Sbjct: 364 LRREQEEERREQQLRREQQLRREQ 387
Score = 48.9 bits (115), Expect = 2e-05
Identities = 52/242 (21%), Positives = 108/242 (44%), Gaps = 30/242 (12%)
Query: 426 QFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRR--KSS 483
Q+ E + L Q+ L E E + +Q L+ Y+ +E + + EE+L R +
Sbjct: 1049 QYREEEELQQEEEQLLGEERETRRRQELERQYR-------KEEELQQEEEQLLREEPEKR 1101
Query: 484 RRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSP 543
RR +Q + + L++ + + ++ +R L++Q + +++ + Q+ + L
Sbjct: 1102 RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYR-----EEEEVQQEEEQLLRE 1156
Query: 544 KRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQD 603
+ +Q Q +E+ QQ E+Q + EQ Q ++ Q ++++ + Q K++ +D
Sbjct: 1157 EPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRD 1216
Query: 604 QQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGNLQA 663
EDQ + K Q E ++ + K+ C+ E++ QF Q L+
Sbjct: 1217 ---EDQRSDLK---------WQWEPEKENAVRDNKVYCKGRENE----QFRQLEDSQLRD 1260
Query: 664 GQ 665
Q
Sbjct: 1261 RQ 1262
Score = 48.9 bits (115), Expect = 2e-05
Identities = 47/253 (18%), Positives = 117/253 (46%), Gaps = 25/253 (9%)
Query: 415 ILPEASTSHIVQFPEIQHLLQQPPDLQPENTEPQ-----------NQQILQMSY-QDIRS 462
+L E + + + L++ P L+ + E Q +Q+LQ Q +R
Sbjct: 1627 LLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRR 1686
Query: 463 EVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQS 522
+ E ++++ EE+ RR+ R L ++ Q LRR L+ + + ++ R +Q+
Sbjct: 1687 Q--ERDRKFREEEQQLRRQERERKFLQEE----QQLRRQELERKFR-EEEQLRQETEQEQ 1739
Query: 523 KGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSK 582
Q +K L++ + L P+R ++Q Q +++ ++ + +Q + EQ Q
Sbjct: 1740 LRRQERYRKILEE---EQLRPER---EEQQLRRQERDRKFREEEQLRQEREEQQLRSQES 1793
Query: 583 DGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQ 642
D + ++++ +++ ++Q + QQ + + E++ + + Q + ++ + + +
Sbjct: 1794 DRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFAT 1853
Query: 643 DSESQIQQYQFWQ 655
+S+ ++ + WQ
Sbjct: 1854 QEKSRREEQELWQ 1866
Score = 48.5 bits (114), Expect = 2e-05
Identities = 40/201 (19%), Positives = 94/201 (46%), Gaps = 11/201 (5%)
Query: 433 LLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQT 492
L ++ LQ E EPQ Q+ LQ + +R +E + + EEE +++ R QQ
Sbjct: 253 LRKEEEKLQEE--EPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR----EQQL 306
Query: 493 KALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQA 552
+ Q R + + Q+ + +++ + + +++ +QQ++ +R ++Q
Sbjct: 307 RRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR--EQQL 364
Query: 553 QLNQTKEQLPDQQAEDQQAKGEQYPEGQS---KDGQVKDQQTDKEQNSKKQTQDQQTEDQ 609
+ Q +E+ Q +QQ + EQ + ++ Q++ +Q + + ++ Q + E Q
Sbjct: 365 RREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 424
Query: 610 PAQEKKSPKGQFQNVQAEGQQ 630
+E++ + + ++ Q +Q
Sbjct: 425 LRREQEEERHEQKHEQERREQ 445
Score = 45.8 bits (107), Expect = 1e-04
Identities = 38/210 (18%), Positives = 97/210 (46%), Gaps = 12/210 (5%)
Query: 439 DLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYL 498
+L+ E E + QQ Q +R + EE +E + E RR+ R ++ + Q
Sbjct: 285 ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE----RREQQERREQQEERREQQLR 340
Query: 499 RRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTK 558
R + + ++ + +QQ + Q +++ +QQ++ + + ++ QL + +
Sbjct: 341 REQEERREQQLRREQEEERREQQLRREQEEERR--EQQLR-----REQQLRREQQLRREQ 393
Query: 559 EQLPDQQ-AEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSP 617
+ +QQ +QQ + EQ + + + + + ++E+ +Q +Q+ +Q + ++
Sbjct: 394 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEE 453
Query: 618 KGQFQNVQAEGQQAQVEKVPKLLCQDSESQ 647
+ + + E ++ + E+ + L +D E +
Sbjct: 454 RRDWLKREEETERHEQERRKQQLKRDQEEE 483
Score = 45.8 bits (107), Expect = 1e-04
Identities = 49/227 (21%), Positives = 103/227 (45%), Gaps = 23/227 (10%)
Query: 426 QFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRR 485
++ E + L Q+ L E E + +Q + Y+ + E+ +E EE+L R + +R
Sbjct: 989 KYREEEELQQEEEQLLREEREKRRRQEWERQYRK-KDELQQE------EEQLLREEREKR 1041
Query: 486 HSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKR 545
Q + QY L + + +R + +Q Q K++ L Q+ + L +
Sbjct: 1042 ---RLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP 1098
Query: 546 HSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQ 605
+Q + Q +E+ QQ E+Q + E + K ++ + E+ +++ + QQ
Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREE----------REKRRRQELERQYREEEEVQQ 1148
Query: 606 TEDQPAQE--KKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQ 650
E+Q +E +K + + + E ++ Q E+ +LL ++ E + Q+
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEE-EQLLREEQEKRRQE 1194
Score = 45.1 bits (105), Expect = 2e-04
Identities = 53/261 (20%), Positives = 116/261 (44%), Gaps = 26/261 (9%)
Query: 429 EIQHLLQQPPDLQP-ENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHS 487
E++ L Q+ Q + EP+ ++ Q+ ++SE EE ++ + E R+ R
Sbjct: 606 EVERLEQEERREQRLKREEPEEERRQQL----LKSEEQEERRQQQLRREQQERREQRLKR 661
Query: 488 LNQQTKALQYLRRHSLDVQ-----AKGQKSSKRHSLDQQSKGWQSPKQKSLD-QQIKDWL 541
++ + Q L+R + + A+ ++ R + + WQ + D +Q K +
Sbjct: 662 EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYS 721
Query: 542 SPKRHSVDKQAQLNQTKEQLPD---QQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSK 598
P++ ++ Q + K + + Q E+++A +Q E Q +D + Q +K + +
Sbjct: 722 RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGR 781
Query: 599 KQ------TQDQQTEDQPAQEKKSPKGQFQNVQAEGQQ---AQVEKVPKLLCQDSESQIQ 649
++ ++Q+ A+E++ + +F + E +Q + E+ +L + E Q+Q
Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ 841
Query: 650 ---QYQFWQFHKGNLQAGQPR 667
+ Q Q + LQ Q R
Sbjct: 842 RRERAQQLQEEEDGLQEDQER 862
Score = 44.3 bits (103), Expect = 4e-04
Identities = 50/234 (21%), Positives = 111/234 (47%), Gaps = 27/234 (11%)
Query: 426 QFPEIQHLLQQPP-DLQPENTEPQNQQILQMSYQDIRSEVMEETKEW--------KSEEE 476
+FP+ + L ++ +L+ + E + QQ + QD R EE KEW K EE+
Sbjct: 203 EFPDEEQLRRRELLELRRKGREEKQQQ--RRERQD-RVFQEEEEKEWRKRETVLRKEEEK 259
Query: 477 LHRRKSSRRHSLNQQTKAL-----QYLRRHSLDVQAKGQKSSKRHSL--DQQSKGWQSPK 529
L + R+ L ++ + L Q LRR + + + Q+ + L Q+ + + +
Sbjct: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319
Query: 530 QKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAED---QQAKGEQYPEGQS----K 582
++ Q+ ++ +R ++ Q + ++QL +Q E+ QQ + EQ E + +
Sbjct: 320 ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR 379
Query: 583 DGQVK-DQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEK 635
+ Q++ +QQ +EQ +++ Q ++ + +++ + Q + Q ++ + E+
Sbjct: 380 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEER 433
Score = 43.1 bits (100), Expect = 8e-04
Identities = 37/197 (18%), Positives = 97/197 (49%), Gaps = 19/197 (9%)
Query: 429 EIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSL 488
E++ ++ L+ E + Q ++ Q Y+ I E E+ + + E++L R++ R+
Sbjct: 1720 ELERKFREEEQLRQETEQEQLRR--QERYRKILEE--EQLRPEREEQQLRRQERDRKFRE 1775
Query: 489 NQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIK-DWLSPKRHS 547
+Q LR+ + Q + Q+S ++ ++Q + Q+ +QQ++ K
Sbjct: 1776 EEQ------LRQEREEQQLRSQESDRKFREEEQLR------QEREEQQLRPQQRDGKYRW 1823
Query: 548 VDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTE 607
++Q QL + +++L +Q D+Q + E+ Q K + + + +E+ ++Q ++++
Sbjct: 1824 EEEQLQLEEQEQRL--RQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLR 1881
Query: 608 DQPAQEKKSPKGQFQNV 624
++ + ++ + + + V
Sbjct: 1882 EEHIRRQQKEEQRHRQV 1898
Score = 41.6 bits (96), Expect = 0.002
Identities = 51/257 (19%), Positives = 115/257 (44%), Gaps = 31/257 (12%)
Query: 424 IVQFPEIQHLLQQPPD---LQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRR 480
++Q E Q L +Q D L+ E + ++ + Q++RS+ E K + E++LHR+
Sbjct: 1469 LLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPER-KFLEEEQQLHRQ 1527
Query: 481 KSSRR-----HSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQ 535
+ R+ L +Q + Q RR D + + ++ ++ +QQ + ++ L++
Sbjct: 1528 QRQRKFLQEEQQLRRQERGQQ--RRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEE 1585
Query: 536 QIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQ---------QAKGEQYPEGQSKDG-- 584
Q +R ++ + QL + + Q +Q D+ Q + EQ Q +D
Sbjct: 1586 QKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKF 1645
Query: 585 ---------QVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEK 635
Q ++QQ +++ K + ++Q ++ Q+ + + + + E Q + E+
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705
Query: 636 VPKLLCQDSESQIQQYQ 652
K L ++ + + Q+ +
Sbjct: 1706 ERKFLQEEQQLRRQELE 1722
Score = 38.5 bits (88), Expect = 0.021
Identities = 41/222 (18%), Positives = 98/222 (44%), Gaps = 20/222 (9%)
Query: 434 LQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTK 493
LQ+ L+ + Q +Q +++ E+ ++ + E++L R++ R+ L +Q
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDRKFRE-----EEQLRQEREEQQLSRQERDRKFRLEEQKV 1588
Query: 494 ALQYLRRHSLDVQAKGQKSSKRHSLDQQ--------SKGWQSPKQKSLDQQIKDWL---- 541
Q R ++ + + ++ + L Q+ + Q +++ L +Q +D
Sbjct: 1589 RRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEE 1648
Query: 542 SPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKD--QQTDKEQNSKK 599
P+ +++ QL +++ ++ + Q EQ Q +D + ++ QQ +++ +K
Sbjct: 1649 EPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERK 1708
Query: 600 QTQ-DQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLL 640
Q +QQ Q + K + Q + + Q + E+ K+L
Sbjct: 1709 FLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKIL 1750
Score = 35.4 bits (80), Expect = 0.17
Identities = 47/242 (19%), Positives = 101/242 (41%), Gaps = 36/242 (14%)
Query: 440 LQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLR 499
LQ +P +Q +++ E+ +++ EE+ RR+ R L ++ Q LR
Sbjct: 1345 LQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEE----QQLR 1400
Query: 500 RHSLDVQAKGQKSSKRHSLDQQ-SKGWQSPKQKSLDQQIK------------DWLSPKRH 546
+ Q + + K +QQ S+ + K + +QQ++ L +RH
Sbjct: 1401 CQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERH 1460
Query: 547 -SVDKQAQLNQTKE--QLPDQQAEDQQAKGEQYPEGQSKDGQVKDQ-------------- 589
++ QL Q +E QL Q+ + + + EQ Q +D + ++Q
Sbjct: 1461 RKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEE 1520
Query: 590 --QTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQ 647
Q ++Q +K Q++Q + + ++ + + + + E Q Q + +L Q+ + +
Sbjct: 1521 EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRK 1580
Query: 648 IQ 649
+
Sbjct: 1581 FR 1582
Score = 33.9 bits (76), Expect = 0.51
Identities = 21/78 (26%), Positives = 45/78 (57%), Gaps = 6/78 (7%)
Query: 582 KDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLC 641
K+ ++D++ +++Q + + +D+Q E++P Q ++ + + + AEG++ Q EK +L
Sbjct: 106 KESLLQDRRQEEDQR-RFEPRDRQLEEEPGQRRRQKRQEQERELAEGEE-QSEKQERLEQ 163
Query: 642 QD----SESQIQQYQFWQ 655
+D E +Q Q WQ
Sbjct: 164 RDRQRRDEELWRQRQEWQ 181
Score = 33.5 bits (75), Expect = 0.66
Identities = 48/264 (18%), Positives = 119/264 (45%), Gaps = 41/264 (15%)
Query: 429 EIQHLL--QQPPDLQ-------------PENTEPQNQQILQMSYQDIRSEVMEETKEWKS 473
++QHLL QQ D + PE + + ++ + +D +S+ ++ +
Sbjct: 1266 DLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREER 1325
Query: 474 EEELHRRKSSRRHSLNQQT---KALQYLRRHSLD-----VQAKGQKSSKRHSLDQQSKGW 525
EE+ R+++ R+ +Q + Q LRR D + + Q+ ++ ++Q
Sbjct: 1326 EEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR 1385
Query: 526 QSPKQKSL--DQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKD 583
Q ++K L +QQ++ ++ D+ + + ++QL Q+ + + + EQ Q ++
Sbjct: 1386 QERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERE 1445
Query: 584 GQV--KDQQTDKEQNSK-------------KQTQDQQTEDQPAQEKKSPKGQFQNVQAEG 628
+ ++QQ +E++ K +Q Q+ + + +E++ + Q ++ +
Sbjct: 1446 RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE 1505
Query: 629 QQAQVEKVPKLLCQDSESQIQQYQ 652
Q+ + ++ P+ + E Q+ + Q
Sbjct: 1506 QELRSQE-PERKFLEEEQQLHRQQ 1528
Score = 32.0 bits (71), Expect = 1.9
Identities = 32/147 (21%), Positives = 73/147 (49%), Gaps = 10/147 (6%)
Query: 506 QAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQ 565
QA G KR D + Q +Q+ ++ + P+ ++++ + +++ Q+
Sbjct: 91 QATGLDEEKRARCDGKESLLQDRRQEEDQRRFE----PRDRQLEEEPGQRRRQKR---QE 143
Query: 566 AEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEK--KSPKGQFQN 623
E + A+GE+ E Q + Q +D+Q E+ +++ + Q+ E++ A+E+ +S KG
Sbjct: 144 QERELAEGEEQSEKQERLEQ-RDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETE 202
Query: 624 VQAEGQQAQVEKVPKLLCQDSESQIQQ 650
+ +Q + ++ +L + E + QQ
Sbjct: 203 EFPDEEQLRRRELLELRRKGREEKQQQ 229
>gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B
[Homo sapiens]
Length = 250
Score = 57.8 bits (138), Expect = 3e-08
Identities = 36/103 (34%), Positives = 56/103 (54%), Gaps = 7/103 (6%)
Query: 41 EPRVLGATQILLALIIVGFGTIFALNYIGFSQRLPLVVLTGYPFWGALIFILTGYLTVTD 100
E + LGA QI++ L +G G+I A +G + L + G+PFWG L FI++G L+V
Sbjct: 68 EGKTLGAIQIIIGLAHIGLGSIMATVLVG--EYLSISFYGGFPFWGGLWFIISGSLSVAA 125
Query: 101 KK---SKLLGQGVTGMNVISSLVAITGIT--FTILSYRHQDKY 138
+ S L G G+N++S++ + G+ T LS H Y
Sbjct: 126 ENQPYSYCLLSGSLGLNIVSAICSAVGVILFITDLSIPHPYAY 168
>gi|73486649 membrane-spanning 4-domains, subfamily A, member 3
isoform a [Homo sapiens]
Length = 214
Score = 56.2 bits (134), Expect = 1e-07
Identities = 38/109 (34%), Positives = 56/109 (51%), Gaps = 5/109 (4%)
Query: 28 YRPHSSLLDFLKGEPRVLGATQILLALIIVGFGTIF-ALNYIGFSQR--LPLVVLTGYPF 84
Y+P D+ K + +VLGA QIL A +I+ G +L Y Q+ TGYP
Sbjct: 34 YQPIDGSPDYQKAKLQVLGAIQILNAAMILALGVFLGSLQYPYHFQKHFFFFTFYTGYPI 93
Query: 85 WGALIFILTGYLTVTD--KKSKLLGQGVTGMNVISSLVAITGITFTILS 131
WGA+ F +G L+V K ++ Q GMN+ S+ +A+ G F L+
Sbjct: 94 WGAVFFCSSGTLSVVAGIKPTRTWIQNSFGMNIASATIALVGTAFLSLN 142
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 55.8 bits (133), Expect = 1e-07
Identities = 89/414 (21%), Positives = 170/414 (41%), Gaps = 61/414 (14%)
Query: 252 PPTLEKKPSENMSIQLDST-FKQMKDEDLQSAIVQPSQMQTKLLQDQAASLQVFPSHSAL 310
PP + + E ++ Q + T QM+ Q ++Q Q Q +AA AL
Sbjct: 593 PPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLAL 652
Query: 311 KLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTSSQDM 370
L+ Q L + + +PS + S V + ++ Q T+SQ
Sbjct: 653 LLQQF-------QTLKMRISDQNIIPSVTRSVSVPDTGSIWE---------LQPTASQPT 696
Query: 371 LFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQFPEI 430
++ + D+ L TP P+ + L Q A A E
Sbjct: 697 VWEGGSVWDLP----LDTTTPG--------PALEQLQQLEKAKAAKLE------------ 732
Query: 431 QHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQ 490
Q + + E E + Q+ L+ ++I EE ++ + EEEL RRK + +L +
Sbjct: 733 QERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK--QEEALRR 790
Query: 491 QTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSL----DQQIKDWLSPKRH 546
Q + LRR + + + Q+ + R +++ + + KQ+ L +++ W R
Sbjct: 791 QREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKW---ARE 847
Query: 547 SVDKQAQLNQTKEQLPDQQA----EDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQ 602
+ Q +L + + ++ ++ A E+++ K ++ + K+ +Q ++Q + ++ Q
Sbjct: 848 EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELM---RQRQQQQEALRRLQ 904
Query: 603 DQQTEDQPAQEK---KSPKGQFQNVQAEGQQAQVEKVP-KLLCQDSESQIQQYQ 652
QQ + Q AQ K S GQ N A QA + + L ++ E Q+++ Q
Sbjct: 905 QQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ 958
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/181 (23%), Positives = 73/181 (40%), Gaps = 12/181 (6%)
Query: 448 QNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKS---SRRHSL----NQQTKALQYLRR 500
+ ++ Q ++ R + EE + EEE +RK R+ L QQ +AL+ L++
Sbjct: 846 REEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQ 905
Query: 501 HSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQ 560
Q K + QQS Q +L L +R ++ Q Q +E
Sbjct: 906 QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL 965
Query: 561 LP--DQQAEDQQAKGEQYPEGQSKDGQVK---DQQTDKEQNSKKQTQDQQTEDQPAQEKK 615
+ QQ + QQ K + G K + Q ++ + +KQ Q QQ QP + +
Sbjct: 966 MKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARN 1025
Query: 616 S 616
+
Sbjct: 1026 N 1026
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 55.8 bits (133), Expect = 1e-07
Identities = 89/414 (21%), Positives = 170/414 (41%), Gaps = 61/414 (14%)
Query: 252 PPTLEKKPSENMSIQLDST-FKQMKDEDLQSAIVQPSQMQTKLLQDQAASLQVFPSHSAL 310
PP + + E ++ Q + T QM+ Q ++Q Q Q +AA AL
Sbjct: 620 PPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLAL 679
Query: 311 KLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTSSQDM 370
L+ Q L + + +PS + S V + ++ Q T+SQ
Sbjct: 680 LLQQF-------QTLKMRISDQNIIPSVTRSVSVPDTGSIWE---------LQPTASQPT 723
Query: 371 LFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQFPEI 430
++ + D+ L TP P+ + L Q A A E
Sbjct: 724 VWEGGSVWDLP----LDTTTPG--------PALEQLQQLEKAKAAKLE------------ 759
Query: 431 QHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQ 490
Q + + E E + Q+ L+ ++I EE ++ + EEEL RRK + +L +
Sbjct: 760 QERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK--QEEALRR 817
Query: 491 QTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSL----DQQIKDWLSPKRH 546
Q + LRR + + + Q+ + R +++ + + KQ+ L +++ W R
Sbjct: 818 QREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKW---ARE 874
Query: 547 SVDKQAQLNQTKEQLPDQQA----EDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQ 602
+ Q +L + + ++ ++ A E+++ K ++ + K+ +Q ++Q + ++ Q
Sbjct: 875 EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELM---RQRQQQQEALRRLQ 931
Query: 603 DQQTEDQPAQEK---KSPKGQFQNVQAEGQQAQVEKVP-KLLCQDSESQIQQYQ 652
QQ + Q AQ K S GQ N A QA + + L ++ E Q+++ Q
Sbjct: 932 QQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ 985
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/181 (23%), Positives = 73/181 (40%), Gaps = 12/181 (6%)
Query: 448 QNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKS---SRRHSL----NQQTKALQYLRR 500
+ ++ Q ++ R + EE + EEE +RK R+ L QQ +AL+ L++
Sbjct: 873 REEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQ 932
Query: 501 HSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQ 560
Q K + QQS Q +L L +R ++ Q Q +E
Sbjct: 933 QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL 992
Query: 561 LP--DQQAEDQQAKGEQYPEGQSKDGQVK---DQQTDKEQNSKKQTQDQQTEDQPAQEKK 615
+ QQ + QQ K + G K + Q ++ + +KQ Q QQ QP + +
Sbjct: 993 MKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARN 1052
Query: 616 S 616
+
Sbjct: 1053 N 1053
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 55.8 bits (133), Expect = 1e-07
Identities = 89/414 (21%), Positives = 170/414 (41%), Gaps = 61/414 (14%)
Query: 252 PPTLEKKPSENMSIQLDST-FKQMKDEDLQSAIVQPSQMQTKLLQDQAASLQVFPSHSAL 310
PP + + E ++ Q + T QM+ Q ++Q Q Q +AA AL
Sbjct: 599 PPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLAL 658
Query: 311 KLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTSSQDM 370
L+ Q L + + +PS + S V + ++ Q T+SQ
Sbjct: 659 LLQQF-------QTLKMRISDQNIIPSVTRSVSVPDTGSIWE---------LQPTASQPT 702
Query: 371 LFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQFPEI 430
++ + D+ L TP P+ + L Q A A E
Sbjct: 703 VWEGGSVWDLP----LDTTTPG--------PALEQLQQLEKAKAAKLE------------ 738
Query: 431 QHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQ 490
Q + + E E + Q+ L+ ++I EE ++ + EEEL RRK + +L +
Sbjct: 739 QERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK--QEEALRR 796
Query: 491 QTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSL----DQQIKDWLSPKRH 546
Q + LRR + + + Q+ + R +++ + + KQ+ L +++ W R
Sbjct: 797 QREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKW---ARE 853
Query: 547 SVDKQAQLNQTKEQLPDQQA----EDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQ 602
+ Q +L + + ++ ++ A E+++ K ++ + K+ +Q ++Q + ++ Q
Sbjct: 854 EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELM---RQRQQQQEALRRLQ 910
Query: 603 DQQTEDQPAQEK---KSPKGQFQNVQAEGQQAQVEKVP-KLLCQDSESQIQQYQ 652
QQ + Q AQ K S GQ N A QA + + L ++ E Q+++ Q
Sbjct: 911 QQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ 964
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/181 (23%), Positives = 73/181 (40%), Gaps = 12/181 (6%)
Query: 448 QNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKS---SRRHSL----NQQTKALQYLRR 500
+ ++ Q ++ R + EE + EEE +RK R+ L QQ +AL+ L++
Sbjct: 852 REEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQ 911
Query: 501 HSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQ 560
Q K + QQS Q +L L +R ++ Q Q +E
Sbjct: 912 QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL 971
Query: 561 LP--DQQAEDQQAKGEQYPEGQSKDGQVK---DQQTDKEQNSKKQTQDQQTEDQPAQEKK 615
+ QQ + QQ K + G K + Q ++ + +KQ Q QQ QP + +
Sbjct: 972 MKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARN 1031
Query: 616 S 616
+
Sbjct: 1032 N 1032
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 55.8 bits (133), Expect = 1e-07
Identities = 89/414 (21%), Positives = 170/414 (41%), Gaps = 61/414 (14%)
Query: 252 PPTLEKKPSENMSIQLDST-FKQMKDEDLQSAIVQPSQMQTKLLQDQAASLQVFPSHSAL 310
PP + + E ++ Q + T QM+ Q ++Q Q Q +AA AL
Sbjct: 599 PPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLAL 658
Query: 311 KLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTSSQDM 370
L+ Q L + + +PS + S V + ++ Q T+SQ
Sbjct: 659 LLQQF-------QTLKMRISDQNIIPSVTRSVSVPDTGSIWE---------LQPTASQPT 702
Query: 371 LFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQFPEI 430
++ + D+ L TP P+ + L Q A A E
Sbjct: 703 VWEGGSVWDLP----LDTTTPG--------PALEQLQQLEKAKAAKLE------------ 738
Query: 431 QHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQ 490
Q + + E E + Q+ L+ ++I EE ++ + EEEL RRK + +L +
Sbjct: 739 QERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK--QEEALRR 796
Query: 491 QTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSL----DQQIKDWLSPKRH 546
Q + LRR + + + Q+ + R +++ + + KQ+ L +++ W R
Sbjct: 797 QREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKW---ARE 853
Query: 547 SVDKQAQLNQTKEQLPDQQA----EDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQ 602
+ Q +L + + ++ ++ A E+++ K ++ + K+ +Q ++Q + ++ Q
Sbjct: 854 EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELM---RQRQQQQEALRRLQ 910
Query: 603 DQQTEDQPAQEK---KSPKGQFQNVQAEGQQAQVEKVP-KLLCQDSESQIQQYQ 652
QQ + Q AQ K S GQ N A QA + + L ++ E Q+++ Q
Sbjct: 911 QQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ 964
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/181 (23%), Positives = 73/181 (40%), Gaps = 12/181 (6%)
Query: 448 QNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKS---SRRHSL----NQQTKALQYLRR 500
+ ++ Q ++ R + EE + EEE +RK R+ L QQ +AL+ L++
Sbjct: 852 REEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQ 911
Query: 501 HSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQ 560
Q K + QQS Q +L L +R ++ Q Q +E
Sbjct: 912 QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL 971
Query: 561 LP--DQQAEDQQAKGEQYPEGQSKDGQVK---DQQTDKEQNSKKQTQDQQTEDQPAQEKK 615
+ QQ + QQ K + G K + Q ++ + +KQ Q QQ QP + +
Sbjct: 972 MKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARN 1031
Query: 616 S 616
+
Sbjct: 1032 N 1032
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 54.3 bits (129), Expect = 4e-07
Identities = 44/253 (17%), Positives = 111/253 (43%), Gaps = 25/253 (9%)
Query: 428 PEIQ-HLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVM----------EETKEWKSEEE 476
P++Q + LQ+ Q E Q ++I + + R E +E K W+ E+
Sbjct: 263 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKR 322
Query: 477 LHRRKSSRRHS---------LNQQTKALQYLRRHSLDVQAKGQKSSKR-----HSLDQQS 522
L ++ R L +Q + +Q + + K ++ ++ L +Q
Sbjct: 323 LREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 382
Query: 523 KGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSK 582
K + +QK DQ+ + W +R ++ Q K ++ +++ EQ + + +
Sbjct: 383 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQ 442
Query: 583 DGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQ 642
+ ++++++ +E+ K + +++ +Q + +K + ++ + E QQ ++ + + L +
Sbjct: 443 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 502
Query: 643 DSESQIQQYQFWQ 655
+ Q Q+ + W+
Sbjct: 503 QEKMQEQEEKIWE 515
Score = 49.3 bits (116), Expect = 1e-05
Identities = 48/234 (20%), Positives = 106/234 (45%), Gaps = 23/234 (9%)
Query: 441 QPENTEPQNQQILQMSYQDIRSEVMEETKE--WKSEEELHRRKSSRRHSLNQQTKALQYL 498
+ E E Q Q++ + + E M+E +E W+ EE++ + Q+ K +
Sbjct: 482 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR----DQEEMWGQEKKMWRQE 537
Query: 499 RRHSLDVQAKGQKSSKRHSLDQQSKGW---QSPKQKSLDQQIKDWLSPKRHSVDKQAQLN 555
+ + Q Q+ R DQ+ K W + ++K+ +Q+ K W ++ +++ +
Sbjct: 538 KMREQEDQMWEQEEKMR---DQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRER 594
Query: 556 QTK----EQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQ------TQDQQ 605
+ K E++ +Q E Q + E+ E + K + +++ ++E+ +Q +++
Sbjct: 595 EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM 654
Query: 606 TEDQPAQEKKSPKGQFQNVQ-AEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHK 658
E Q E+K + + +Q E Q Q EK+ + + ++Q Q+ + W K
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEK 708
Score = 45.8 bits (107), Expect = 1e-04
Identities = 36/217 (16%), Positives = 98/217 (45%), Gaps = 26/217 (11%)
Query: 458 QDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHS 517
Q+ + ++ ++ + EE + R+ R + + +++ ++ + +K ++
Sbjct: 433 QEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 492
Query: 518 L-DQQSKGWQSPKQKSLDQQI------------------KDWLSPKRHSVDKQAQLNQTK 558
L +Q+ K W+ K + +++I K W K + Q + K
Sbjct: 493 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 552
Query: 559 EQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPK 618
+ +Q+ DQ+ + E+ + Q K + D+E+ +++ + ++ E + +E++ +
Sbjct: 553 MRDQEQKMWDQEERMEKKTQEQEK------KTWDQEEKMREEERMREREKKMREEEEMMR 606
Query: 619 GQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQ 655
Q + +Q + ++ Q E+ K+ Q+ + Q Q+ + W+
Sbjct: 607 EQEEKMQEQEEKMQ-EQEEKMWEQEEKMQEQEEKMWE 642
Score = 43.5 bits (101), Expect = 6e-04
Identities = 39/239 (16%), Positives = 103/239 (43%), Gaps = 19/239 (7%)
Query: 431 QHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQ 490
Q + Q ++ + E + + Q + E K+ + EEE+ R + + + +
Sbjct: 558 QKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK---MQE 614
Query: 491 QTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPK-----QKSLDQQIKDWLSPKR 545
Q + +Q + + K Q+ ++ +Q+ K W+ + Q+ +Q+ K W K
Sbjct: 615 QEEKMQEQEEKMWEQEEKMQEQEEK-MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM 673
Query: 546 HSVDKQAQLNQT---------KEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQN 596
+K + + K Q +++ DQ+ E+ + + ++++ +EQ
Sbjct: 674 QEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQE 733
Query: 597 SKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQ 655
K Q Q+++ ++Q + + + ++ + +Q ++ + + L + + Q +Q + W+
Sbjct: 734 EKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ-EQEKIWE 791
Score = 43.1 bits (100), Expect = 8e-04
Identities = 48/234 (20%), Positives = 108/234 (46%), Gaps = 28/234 (11%)
Query: 429 EIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEEL--HRRKSSRRH 486
E + +Q+ + E E +Q +M Q+ + EE K W+ EE++ +R ++
Sbjct: 607 EQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE-KMWEQEEKMWEQQRLPEQKE 665
Query: 487 SLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPK---QKSLDQQIKDWLSP 543
L + K + + + + Q+ ++ + +Q+ K W K ++S+ ++ K
Sbjct: 666 KLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREE 725
Query: 544 KRHSVDKQAQLNQTKEQLPDQQAE---------DQQAK---GEQYPEGQSK---DGQVKD 588
+ +++ ++ + +E++ +Q+ E +Q+ K ++ PE + K ++++
Sbjct: 726 EEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQE 785
Query: 589 QQTDKEQNSKKQTQDQ----QTEDQPAQEKKSPKGQFQNV--QAEGQQAQVEKV 636
Q+ EQ K + Q++ Q E QE+K +GQ + + Q E Q EK+
Sbjct: 786 QEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKM-RGQEEKMWGQEEKMWGQEEKM 838
Score = 42.7 bits (99), Expect = 0.001
Identities = 39/211 (18%), Positives = 91/211 (43%), Gaps = 5/211 (2%)
Query: 429 EIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSL 488
E + +Q+ + E E +Q +M Q+ R + E+ K+ + +E+ R + R
Sbjct: 345 EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER--LWEQEKQMREQEQKMRDQEERMWEQ 402
Query: 489 NQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSV 548
+++ + + R + + +K + + +Q K + ++K +++ K
Sbjct: 403 DERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREE 462
Query: 549 DKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTED 608
++ + + K Q ++ +Q+ K Q + ++ +Q+ +EQ K Q+++ D
Sbjct: 463 EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD 522
Query: 609 QP---AQEKKSPKGQFQNVQAEGQQAQVEKV 636
Q QEKK + + Q + Q EK+
Sbjct: 523 QEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 553
Score = 40.4 bits (93), Expect = 0.005
Identities = 38/219 (17%), Positives = 94/219 (42%), Gaps = 13/219 (5%)
Query: 431 QHLLQQPPDLQPENTEPQNQQILQMSYQDIR-----SEVMEETKEWKSEEELHRRKSSRR 485
+ L +Q ++ + + ++Q+ +M QD R + E+ K W+ E++ K +
Sbjct: 376 ERLWEQEKQMREQEQKMRDQEE-RMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQE 434
Query: 486 HSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKR 545
+ + + + + K + + +Q+ K Q ++ +Q+ K+W +R
Sbjct: 435 QEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEK-MQKQEENMWEQEEKEW-QQQR 492
Query: 546 HSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQ 605
K+ Q K Q +++ +Q+ K E ++ ++ Q+ +EQ + Q+++
Sbjct: 493 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 552
Query: 606 TEDQ-----PAQEKKSPKGQFQNVQAEGQQAQVEKVPKL 639
DQ +E+ K Q Q + Q+ ++ + ++
Sbjct: 553 MRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERM 591
Score = 40.0 bits (92), Expect = 0.007
Identities = 50/226 (22%), Positives = 104/226 (46%), Gaps = 19/226 (8%)
Query: 429 EIQHLLQQPPDLQPENTEPQNQQILQMSYQDI-RSEVMEETKEWKSEEELHRRKSSRRHS 487
E Q L +Q L E+ + Q Q+ +Q + I E ME+ + + ++ + K S
Sbjct: 656 EQQRLPEQKEKLW-EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEES 714
Query: 488 LNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHS 547
+ ++ K ++ + + K Q+ ++ +Q+ + W+ ++K +Q+ K W
Sbjct: 715 MREREKKMREEEEMMREQEEKMQEQEEKMQ-EQEEEMWEQ-EEKMWEQEEKMW------- 765
Query: 548 VDKQAQLNQTKEQLPDQQAEDQQAK-GEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQT 606
+Q +L + KE+L + + +Q K EQ E + +D + K + +++ +++ Q
Sbjct: 766 --EQQRLPEQKEKLWEHEKMQEQEKIWEQ--EEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821
Query: 607 EDQPAQEKKSPKGQFQNV--QAEGQQAQVEKVPKLLCQDSESQIQQ 650
E QE+K GQ + + Q E Q EK+ + + E +Q
Sbjct: 822 EKMWGQEEKM-WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQ 866
Score = 39.7 bits (91), Expect = 0.009
Identities = 42/237 (17%), Positives = 104/237 (43%), Gaps = 30/237 (12%)
Query: 426 QFPEIQHLLQQPPDLQP-ENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSR 484
+ PE + L + +Q E + Q ++I + + +++ E+ K W E+
Sbjct: 659 RLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK-KTWDQEKMREEESMRE 717
Query: 485 RHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPK-----QKSLDQQIKD 539
R ++ + + + + Q + + + +Q+ K W+ + Q+ +Q+ K
Sbjct: 718 REKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKL 777
Query: 540 WLSPKRHSVDKQAQLNQTKEQLPDQQ----AEDQQAKG-EQYPEGQSKD---------GQ 585
W + + +Q ++ + +E++ DQ+ ++++ +G E+ GQ + GQ
Sbjct: 778 W---EHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQ 834
Query: 586 VKDQQTDKE----QNSKKQTQDQQTEDQPAQEKKSPKGQFQNV--QAEGQQAQVEKV 636
+ +E Q K + + Q E++ ++++ +GQ + + Q E + Q EK+
Sbjct: 835 EEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 54.3 bits (129), Expect = 4e-07
Identities = 47/234 (20%), Positives = 112/234 (47%), Gaps = 11/234 (4%)
Query: 425 VQFPEIQHLL-QQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSS 483
V+ E+ +LL QQ + E +Q +M Q+++ EE K W+ EE++H ++
Sbjct: 282 VEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEE-KMWRQEEKMHEQEEK 340
Query: 484 RRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSP 543
R ++ + + +R ++ + +K + +Q + + +K +Q+ + W
Sbjct: 341 IREQEDKMWRQEEKIREQEEKIREQEEK------MWRQEEKIREQDEKIQEQEEEMWRQE 394
Query: 544 K--RHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQT 601
+ R +K+ + +E+ +Q E + + E+ + K ++++ D+E+ ++
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVE 454
Query: 602 QDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQ 655
+ Q E++ QE++ K Q Q + + Q+ + + KLL Q+ + Q+ + W+
Sbjct: 455 EKMQEEEEKMQEQEE-KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507
Score = 45.4 bits (106), Expect = 2e-04
Identities = 38/204 (18%), Positives = 95/204 (46%), Gaps = 19/204 (9%)
Query: 466 EETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQA------KGQKSSKRHSLD 519
+E K W+ EE++ ++ R + + + +R +Q + ++ +
Sbjct: 344 QEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK 403
Query: 520 QQSKGW-QSPKQKSLDQQIKD-----WLSPKR-HSVDKQAQLNQTK-EQLPDQQAEDQQA 571
+Q K W Q K + D++I++ W ++ +++ Q + K ++ ++ E+++
Sbjct: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEK 463
Query: 572 KGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQA 631
EQ + Q ++ ++++Q+ + K Q+++ +Q +EK + + Q E Q
Sbjct: 464 MQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ--EEKMWRQEEKMWEQEEKMQE 521
Query: 632 QVEKVPKLLCQDSESQIQQYQFWQ 655
Q EK+ + Q+ + + Q+ + WQ
Sbjct: 522 QEEKMQR---QEEKMREQEVRLWQ 542
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 54.3 bits (129), Expect = 4e-07
Identities = 47/234 (20%), Positives = 112/234 (47%), Gaps = 11/234 (4%)
Query: 425 VQFPEIQHLL-QQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSS 483
V+ E+ +LL QQ + E +Q +M Q+++ EE K W+ EE++H ++
Sbjct: 282 VEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEE-KMWRQEEKMHEQEEK 340
Query: 484 RRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSP 543
R ++ + + +R ++ + +K + +Q + + +K +Q+ + W
Sbjct: 341 IREQEDKMWRQEEKIREQEEKIREQEEK------MWRQEEKIREQDEKIQEQEEEMWRQE 394
Query: 544 K--RHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQT 601
+ R +K+ + +E+ +Q E + + E+ + K ++++ D+E+ ++
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVE 454
Query: 602 QDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQ 655
+ Q E++ QE++ K Q Q + + Q+ + + KLL Q+ + Q+ + W+
Sbjct: 455 EKMQEEEEKMQEQEE-KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507
Score = 45.4 bits (106), Expect = 2e-04
Identities = 38/204 (18%), Positives = 95/204 (46%), Gaps = 19/204 (9%)
Query: 466 EETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQA------KGQKSSKRHSLD 519
+E K W+ EE++ ++ R + + + +R +Q + ++ +
Sbjct: 344 QEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK 403
Query: 520 QQSKGW-QSPKQKSLDQQIKD-----WLSPKR-HSVDKQAQLNQTK-EQLPDQQAEDQQA 571
+Q K W Q K + D++I++ W ++ +++ Q + K ++ ++ E+++
Sbjct: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEK 463
Query: 572 KGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQA 631
EQ + Q ++ ++++Q+ + K Q+++ +Q +EK + + Q E Q
Sbjct: 464 MQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ--EEKMWRQEEKMWEQEEKMQE 521
Query: 632 QVEKVPKLLCQDSESQIQQYQFWQ 655
Q EK+ + Q+ + + Q+ + WQ
Sbjct: 522 QEEKMQR---QEEKMREQEVRLWQ 542
>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 1 [Homo
sapiens]
Length = 1834
Score = 52.8 bits (125), Expect = 1e-06
Identities = 44/238 (18%), Positives = 111/238 (46%), Gaps = 14/238 (5%)
Query: 410 LSAHAILPEASTSHIVQFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETK 469
L+A + PE ++ +Q P+ + + P QP E ++ Q + +S +++ S
Sbjct: 1456 LTAQQMKPEKPST--LQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPD 1513
Query: 470 EWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQ-SKGWQSP 528
WK + + K + H ++ +K +Q L+ D A+ ++ L+ Q K Q
Sbjct: 1514 PWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKP-DRSAEESDRLRKLMLEWQFQKRLQES 1572
Query: 529 KQKSLDQQ------IKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSK 582
KQK D + + L +R +++A+ + D ++++ + +Q E + +
Sbjct: 1573 KQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEERRRQQQLEEMRKR 1632
Query: 583 DGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLL 640
+ + + +Q + +++ ++++T+ ++++ +G + ++AE ++ E +LL
Sbjct: 1633 EAEDRARQ----EEERRRQEEERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLL 1686
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 52.4 bits (124), Expect = 1e-06
Identities = 35/210 (16%), Positives = 97/210 (46%), Gaps = 9/210 (4%)
Query: 426 QFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRR 485
Q E + +Q+ + E E +Q QM Q+ + + EE + K EE++ +++ R
Sbjct: 207 QMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQ-KQEEQMRKQEEQMR 265
Query: 486 HSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKR 545
Q + + + + + + Q + + +Q + + +++ +Q+
Sbjct: 266 EQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQE--------E 317
Query: 546 HSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQ 605
+++ Q+ + +EQ+ +Q+ + + K + + + + Q + Q +EQ K++ Q ++
Sbjct: 318 QMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRK 377
Query: 606 TEDQPAQEKKSPKGQFQNVQAEGQQAQVEK 635
E+Q ++++ + Q + + + +Q +K
Sbjct: 378 QEEQMRKQEEQMRKQEEQMGEQKEQMGEQK 407
Score = 50.1 bits (118), Expect = 7e-06
Identities = 37/192 (19%), Positives = 87/192 (45%), Gaps = 7/192 (3%)
Query: 426 QFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRR 485
Q + + +++ + E E +Q QM Q ++E E+T E EE++ ++ R
Sbjct: 249 QVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGE--QEEQMREQEEQMR 306
Query: 486 HSLNQQTKALQYLRRHS--LDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSP 543
Q + + +R + Q + K +Q+ + W+ +Q + ++ +
Sbjct: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMG---EQEEQMQK 363
Query: 544 KRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQD 603
+ V KQ + + +E+ +Q E + + EQ E + + G+ K+Q ++E+ +Q +
Sbjct: 364 QEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQ 423
Query: 604 QQTEDQPAQEKK 615
+ +++ E+K
Sbjct: 424 MRKQEEHMGEQK 435
Score = 49.7 bits (117), Expect = 9e-06
Identities = 43/225 (19%), Positives = 102/225 (45%), Gaps = 13/225 (5%)
Query: 443 ENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHS 502
E +Q QM Q+ + EE + K EE++ ++ R Q + + +++
Sbjct: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQMQ-KQEEQMGEQEEQMRKQEEQMGEQEEQVQKQE 247
Query: 503 LDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLP 562
VQ + ++ K+ ++Q + + ++ +Q +K ++ +++ Q + +EQ+
Sbjct: 248 EQVQKQEEQMRKQ---EEQMREQEEQMREQEEQMLK-----QKEQTEQEEQTGEQEEQMR 299
Query: 563 DQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQ 622
+Q E+Q + E+ Q + + +++Q K++ + ++Q E + K+ + Q
Sbjct: 300 EQ--EEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQ 357
Query: 623 NVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGNLQAGQPR 667
Q + Q+ QV K + + + E +Q + Q K Q G+ +
Sbjct: 358 EEQMQKQEEQVRKQEEQMRKQEEQMRKQEE--QMRKQEEQMGEQK 400
Score = 44.7 bits (104), Expect = 3e-04
Identities = 27/156 (17%), Positives = 79/156 (50%), Gaps = 8/156 (5%)
Query: 506 QAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQ- 564
+ +GQ + + +Q +G +++ + +Q + + +++ Q+ + +EQ+ +Q
Sbjct: 182 EQEGQVREQEGQMGEQ-EGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
Query: 565 -----QAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKG 619
Q E Q + EQ + + + + ++Q ++E+ KQ + + E+Q ++++ +
Sbjct: 241 EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMRE 300
Query: 620 QFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQ 655
Q + ++ + +Q + E+ ++ Q+ + Q+ Q W+
Sbjct: 301 QEEQMREQEEQMR-EQEEQMREQEEQMGKQEEQMWE 335
Score = 40.0 bits (92), Expect = 0.007
Identities = 31/189 (16%), Positives = 85/189 (44%), Gaps = 4/189 (2%)
Query: 466 EETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGW 525
+E + + E ++ ++ R Q + +R V+ + + ++ ++ +G
Sbjct: 127 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 186
Query: 526 QSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAE---DQQAKGEQYPEGQSK 582
++ + +Q + +++ Q+ + +EQ+ +Q+ + ++ GEQ + Q +
Sbjct: 187 VREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQ 246
Query: 583 DGQVKDQQTD-KEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLC 641
+ QV+ Q+ ++Q + + Q++Q +Q Q K + Q Q Q+ Q+ + + +
Sbjct: 247 EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306
Query: 642 QDSESQIQQ 650
+ E +Q
Sbjct: 307 EQEEQMREQ 315
Score = 38.1 bits (87), Expect = 0.027
Identities = 48/233 (20%), Positives = 109/233 (46%), Gaps = 22/233 (9%)
Query: 439 DLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYL 498
+L+ +N E Q + LQ+ + +SE+ KE K + E + + + +Q ++
Sbjct: 8 ELKEKNAELQEE--LQLVETE-KSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVR-- 62
Query: 499 RRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTK 558
+ Q + Q+ R Q + Q + + + Q+++ R +++ Q+ + +
Sbjct: 63 ---EQEGQVREQEGQVREQEGQVRE--QEGQVREQEGQVREQEGQVR---EQEGQVREQE 114
Query: 559 EQLPDQQAEDQQAKG---EQYPEGQSKDGQVKDQQTD-KEQNSKKQTQDQQTEDQPAQEK 614
Q+ +Q+ + ++ +G EQ + + ++GQV++Q+ +EQ + + Q+ Q +Q Q +
Sbjct: 115 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 174
Query: 615 KSPKGQF--QNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGNLQAGQ 665
+ +GQ Q Q Q+ Q+ + + + E +Q + Q K Q G+
Sbjct: 175 EQ-EGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEE--QMQKQEEQMGE 224
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 52.4 bits (124), Expect = 1e-06
Identities = 70/381 (18%), Positives = 162/381 (42%), Gaps = 36/381 (9%)
Query: 308 SALKLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTSS 367
SA+ + ++ +AL V +E +P ++ + + +N A LP G+L
Sbjct: 88 SAVVAQHLTNTVFVDRALIVVPYAEGVIPDEAKALSLLAPANAVAGLLPGGGLLPTP--- 144
Query: 368 QDMLFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQF 427
+ +T L L T A+ +P ++ SQ+L+A +L ST
Sbjct: 145 -----NPLTQIGAVPLAALGAPTLDPALAALGLPGANLNSQSLAADQLLKLMSTVD---- 195
Query: 428 PEIQHLLQQ--PPDLQPENTEPQNQQILQM--SYQDIRSEVMEETKEWKSEEELHRRKSS 483
P++ H+ P L+ + + + ++ ++ Q + S +E K+ + R S
Sbjct: 196 PKLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRS 255
Query: 484 RRH-----SLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQS-------PKQK 531
RR S ++++++ R HS + KS +R + +G +S K+K
Sbjct: 256 RRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKK 315
Query: 532 SLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQ-SKDGQVKDQQ 590
++ + PK +S ++++ + + ++ + K + P+ + S+ + +
Sbjct: 316 EDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHK 375
Query: 591 TDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQ 650
+K+++ K+ + E +++KKS + + ++++ +K K + +D + + Q
Sbjct: 376 KEKKKDKDKERSRDERERSTSKKKKSKDKE----KDRERKSESDKDVKQVTRDYDEEEQG 431
Query: 651 YQFWQFHKGN---LQAGQPRT 668
Y + K ++ G P+T
Sbjct: 432 YDSEKEKKEEKKPIETGSPKT 452
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 51.6 bits (122), Expect = 2e-06
Identities = 40/201 (19%), Positives = 94/201 (46%), Gaps = 19/201 (9%)
Query: 466 EETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLD----QQ 521
+E K W+ EE++H ++ R Q+ + + + + ++ K H + Q+
Sbjct: 435 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQE 494
Query: 522 SKGWQSPK------QKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQA---EDQQAK 572
K W+ + +K +Q+ K W ++ +++ ++ + +E++ +Q+ E ++
Sbjct: 495 EKVWRQEEKMHDQEEKIREQEEKMWRQEEKIR-EQEEKIREQEEKIREQEEMMQEQEEKM 553
Query: 573 GEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQ 632
GEQ + Q ++ + ++ +EQ K + Q ++ +Q +EK + + Q E Q Q
Sbjct: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQ--EEKIWEQEEKIREQEEMMQEQ 611
Query: 633 VEKV---PKLLCQDSESQIQQ 650
EK+ + +C+ E +Q
Sbjct: 612 EEKMWEQEEKMCEQEEKMQEQ 632
Score = 41.6 bits (96), Expect = 0.002
Identities = 42/234 (17%), Positives = 107/234 (45%), Gaps = 36/234 (15%)
Query: 446 EPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDV 505
E + Q+ ++ Q+ R E +E K W+ EE++ ++ R +Q K + + + +
Sbjct: 396 EEKRQEEEKIREQEKRQE--QEAKMWRQEEKIREQEEKIR----EQEKKM-WRQEEKIHE 448
Query: 506 QAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQ 565
Q K ++ KR +Q + W+ +++ + +Q + W ++ ++ + + K +++
Sbjct: 449 QEKIREEEKRQ---EQEEMWR--QEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEK 503
Query: 566 AEDQQAK---------------GEQYPEGQSKDGQVKDQQTD-KEQNSKKQTQDQQTEDQ 609
DQ+ K EQ + + ++ ++++Q+ +EQ K Q+++ ++Q
Sbjct: 504 MHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ 563
Query: 610 PAQEKKSPKGQFQNVQAEGQQAQV--------EKVPKLLCQDSESQIQQYQFWQ 655
++ K + Q + Q+ ++ E+ K+ Q+ Q Q+ + W+
Sbjct: 564 EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWE 617
Score = 39.7 bits (91), Expect = 0.009
Identities = 28/151 (18%), Positives = 69/151 (45%), Gaps = 9/151 (5%)
Query: 466 EETKEWKSEEELHRRKSSRRHS---LNQQTKALQYLRRHSLDVQAKGQKSSK----RHSL 518
+E K W+ EE++ ++ R + +Q + +Q + + K Q+ K +
Sbjct: 514 QEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKI 573
Query: 519 DQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPE 578
+Q + + K+K +Q+ K W + + +Q ++ Q +E+ +Q E + E+ E
Sbjct: 574 REQEEKIREQKEKIREQEEKIW--EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 631
Query: 579 GQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQ 609
+ K + +++ ++E ++Q + Q +
Sbjct: 632 QEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 35.0 bits (79), Expect = 0.23
Identities = 51/284 (17%), Positives = 117/284 (41%), Gaps = 27/284 (9%)
Query: 369 DMLFHDMTSQ-DMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHI-VQ 426
D ++T + D SL++ + ++ Q+ L L E+ S I +
Sbjct: 192 DRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQ--------LVESEKSEIQLN 243
Query: 427 FPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRH 486
E++ L++ L P+ L Q + +++ + +E EL R
Sbjct: 244 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE----NELWNR------ 293
Query: 487 SLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRH 546
LNQQ + + + + + + + + + +Q + + ++K Q+ W K
Sbjct: 294 -LNQQQEEKMWRQEEKIQ-EWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW--EKEE 349
Query: 547 SVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQT 606
+ +Q ++ KE+ + E K E+ E + K + +Q+ +EQ K+Q +++
Sbjct: 350 KMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEK---MHEQEKIREQEEKRQEEEKIR 406
Query: 607 EDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQ 650
E + QE+++ + + E ++ E+ K+ Q+ + Q+
Sbjct: 407 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE 450
Score = 34.7 bits (78), Expect = 0.30
Identities = 31/187 (16%), Positives = 91/187 (48%), Gaps = 18/187 (9%)
Query: 466 EETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGW 525
+E K + EE++H ++ R Q+ K R+ ++ + ++ + + +Q +
Sbjct: 375 KEEKIRELEEKMHEQEKIR----EQEEK-----RQEEEKIREQEKRQEQEAKMWRQEEKI 425
Query: 526 QSPKQKSLDQQIKDWLSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQ 585
+ ++K +Q+ K W ++ + +Q ++ + +++ ++ Q+ K + E + +
Sbjct: 426 REQEEKIREQEKKMWRQEEK--IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 483
Query: 586 VKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSE 645
+ +Q+ ++Q K Q+++ DQ + ++ + ++ Q E + Q EK+ ++ E
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWR--QEEKIREQEEKI-----REQE 536
Query: 646 SQIQQYQ 652
+I++ +
Sbjct: 537 EKIREQE 543
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 50.8 bits (120), Expect = 4e-06
Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 44/235 (18%)
Query: 440 LQPENTEP-QNQQILQMSYQDIRSEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYL 498
+Q TE N + Q + S++ +++ +S + S+ QQ +ALQ
Sbjct: 2 MQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAA 61
Query: 499 RRHSLDVQAKGQKSSKRHSLDQQ-------SKGWQSPK-------QKSLDQQIKDWLSP- 543
R+ L Q G KS K S D+Q S +P+ Q+ L QQ+ LSP
Sbjct: 62 RQLLLQQQTSGLKSPK--SSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQV---LSPQ 116
Query: 544 -----------------------KRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQ 580
K+ QL Q ++Q QQ + QQ + +Q + Q
Sbjct: 117 QLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQ 176
Query: 581 SKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEK 635
+ Q + QQ ++Q+ KQ ++QQ + Q Q+ + + FQ + QQ Q ++
Sbjct: 177 QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQ 231
Score = 43.1 bits (100), Expect = 8e-04
Identities = 56/245 (22%), Positives = 100/245 (40%), Gaps = 24/245 (9%)
Query: 323 QALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGILSQDTSSQDMLFHDMTSQDMQS 382
Q E +S +M S+ SS L A G S DTSS+ + Q Q+
Sbjct: 3 QESATETISNSSMNQNGMST---LSSQLDAGSR--DGRSSGDTSSEVSTVELLHLQQQQA 57
Query: 383 LD----MLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEASTSHIVQFPEIQHLLQQPP 438
L +L Q S P+ Q L +S + P+ T ++Q +LQQ
Sbjct: 58 LQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQ-----QMQQILQQ-- 110
Query: 439 DLQPENTEPQNQQILQMSYQDIRSEVMEETKEW--KSEEELHRRKSSRRHSLNQQTKALQ 496
+ PQ Q L Q + + ++ +E+ K +E+LH + ++ QQ + Q
Sbjct: 111 ----QVLSPQQLQALLQQQQAVMLQ-QQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQ 165
Query: 497 YLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDWLSPKRHSVDKQ-AQLN 555
++ Q + Q+ ++ QQ + K++ QQ + L+ ++ +Q Q+
Sbjct: 166 QQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQ 225
Query: 556 QTKEQ 560
Q ++Q
Sbjct: 226 QLQQQ 230
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,106,919
Number of Sequences: 37866
Number of extensions: 1243342
Number of successful extensions: 8689
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 139
Number of HSP's successfully gapped in prelim test: 709
Number of HSP's that attempted gapping in prelim test: 6005
Number of HSP's gapped (non-prelim): 2403
length of query: 679
length of database: 18,247,518
effective HSP length: 109
effective length of query: 570
effective length of database: 14,120,124
effective search space: 8048470680
effective search space used: 8048470680
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.