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Search of human proteins with 239753578
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239753578 PREDICTED: similar to cartilage associated protein
[Homo sapiens]
(241 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239753578 PREDICTED: similar to cartilage associated protein ... 498 e-141
gi|5453601 cartilage associated protein precursor [Homo sapiens] 337 7e-93
gi|5454038 synaptonemal complex protein SC65 [Homo sapiens] 172 3e-43
gi|27764882 leprecan-like 1 isoform a [Homo sapiens] 81 9e-16
gi|186928835 leprecan 1 isoform 1 [Homo sapiens] 75 7e-14
gi|226371643 leprecan 1 isoform 2 [Homo sapiens] 75 7e-14
gi|28466983 leprecan-like 2 [Homo sapiens] 51 1e-06
gi|108773804 Fraser syndrome 1 [Homo sapiens] 32 0.38
gi|221554526 coiled-coil domain containing 42B [Homo sapiens] 31 0.84
gi|4503327 cytochrome b5 reductase 3 isoform m [Homo sapiens] 31 1.1
gi|193794826 cytochrome b5 reductase 3 isoform s [Homo sapiens] 31 1.1
gi|6552328 cytochrome b5 reductase 3 isoform s [Homo sapiens] 31 1.1
gi|21217561 Shaw-related voltage-gated potassium channel protein... 30 1.9
gi|239753555 PREDICTED: hypothetical protein XP_002345695 [Homo ... 30 2.5
gi|115527106 vitelliform macular dystrophy 2-like 3 isoform 2 [H... 29 3.2
gi|115527104 vitelliform macular dystrophy 2-like 3 isoform 1 [H... 29 3.2
gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens] 28 9.3
gi|8923763 centaurin-alpha 2 protein [Homo sapiens] 28 9.3
gi|63999355 chromosome 9 open reading frame 37 [Homo sapiens] 28 9.3
gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens] 28 9.3
>gi|239753578 PREDICTED: similar to cartilage associated protein
[Homo sapiens]
Length = 241
Score = 498 bits (1283), Expect = e-141
Identities = 241/241 (100%), Positives = 241/241 (100%)
Query: 1 MEPGRRGAAALLALLCVACALRAGRAQYERYSFRSFPRDELMPLESAYRHALDKYSGEHW 60
MEPGRRGAAALLALLCVACALRAGRAQYERYSFRSFPRDELMPLESAYRHALDKYSGEHW
Sbjct: 1 MEPGRRGAAALLALLCVACALRAGRAQYERYSFRSFPRDELMPLESAYRHALDKYSGEHW 60
Query: 61 AESVGYLEISLRLHRLLRDSEAFCHRNCSAAPQPEPAAGLASYPELRLFGGLLRRAHCLK 120
AESVGYLEISLRLHRLLRDSEAFCHRNCSAAPQPEPAAGLASYPELRLFGGLLRRAHCLK
Sbjct: 61 AESVGYLEISLRLHRLLRDSEAFCHRNCSAAPQPEPAAGLASYPELRLFGGLLRRAHCLK 120
Query: 121 RCKQGLPAFRQSQPSREVLADFQRREPYKFLQFAYFKANNLPKCWDYKQPGNRETMIHVQ 180
RCKQGLPAFRQSQPSREVLADFQRREPYKFLQFAYFKANNLPKCWDYKQPGNRETMIHVQ
Sbjct: 121 RCKQGLPAFRQSQPSREVLADFQRREPYKFLQFAYFKANNLPKCWDYKQPGNRETMIHVQ 180
Query: 181 SPRRVIKLLKAGPPDCSSKGSLPREDACKTQIVLSWSHAAARSLLAAPTRPARPQRGGAR 240
SPRRVIKLLKAGPPDCSSKGSLPREDACKTQIVLSWSHAAARSLLAAPTRPARPQRGGAR
Sbjct: 181 SPRRVIKLLKAGPPDCSSKGSLPREDACKTQIVLSWSHAAARSLLAAPTRPARPQRGGAR 240
Query: 241 G 241
G
Sbjct: 241 G 241
>gi|5453601 cartilage associated protein precursor [Homo sapiens]
Length = 401
Score = 337 bits (863), Expect = 7e-93
Identities = 163/163 (100%), Positives = 163/163 (100%)
Query: 1 MEPGRRGAAALLALLCVACALRAGRAQYERYSFRSFPRDELMPLESAYRHALDKYSGEHW 60
MEPGRRGAAALLALLCVACALRAGRAQYERYSFRSFPRDELMPLESAYRHALDKYSGEHW
Sbjct: 1 MEPGRRGAAALLALLCVACALRAGRAQYERYSFRSFPRDELMPLESAYRHALDKYSGEHW 60
Query: 61 AESVGYLEISLRLHRLLRDSEAFCHRNCSAAPQPEPAAGLASYPELRLFGGLLRRAHCLK 120
AESVGYLEISLRLHRLLRDSEAFCHRNCSAAPQPEPAAGLASYPELRLFGGLLRRAHCLK
Sbjct: 61 AESVGYLEISLRLHRLLRDSEAFCHRNCSAAPQPEPAAGLASYPELRLFGGLLRRAHCLK 120
Query: 121 RCKQGLPAFRQSQPSREVLADFQRREPYKFLQFAYFKANNLPK 163
RCKQGLPAFRQSQPSREVLADFQRREPYKFLQFAYFKANNLPK
Sbjct: 121 RCKQGLPAFRQSQPSREVLADFQRREPYKFLQFAYFKANNLPK 163
Score = 33.9 bits (76), Expect = 0.13
Identities = 28/123 (22%), Positives = 51/123 (41%), Gaps = 14/123 (11%)
Query: 40 ELMPLESAYRHALDKYSGEHWAESVGYLEISL-RLHRLLRDSEAFCHRNCSAAPQPEPAA 98
E ES + A+ Y+GE+W S+ +E++L + + A C + +
Sbjct: 202 ETKSYESLFIRAVRAYNGENWRTSITDMELALPDFFKAFYECLAACEGSREIKDFKDFYL 261
Query: 99 GLASYPELRLFGGLLRRAHCLKRCKQGLPAFRQSQPSREVLADFQRREPYKFLQFAYFKA 158
+A + + C +C++ L P + +A Y +LQFAY+K
Sbjct: 262 SIADH--------YVEVLECKIQCEENLTPVIGGYPVEKFVATM-----YHYLQFAYYKL 308
Query: 159 NNL 161
N+L
Sbjct: 309 NDL 311
>gi|5454038 synaptonemal complex protein SC65 [Homo sapiens]
Length = 437
Score = 172 bits (435), Expect = 3e-43
Identities = 87/148 (58%), Positives = 106/148 (71%), Gaps = 5/148 (3%)
Query: 21 LRAGRAQYERYSFRSFPRDELMPLESAYRHALDKYSGEHWAESVGYLEISLRLHRLLRDS 80
L + AQYE+YSFR FP ++LMPL +AY HAL++Y GE W ES YLE +LRLHRLLRDS
Sbjct: 13 LGSAGAQYEKYSFRGFPPEDLMPLAAAYGHALEQYEGESWRESARYLEAALRLHRLLRDS 72
Query: 81 EAFCHRNCSA---APQPEPAAGLAS--YPELRLFGGLLRRAHCLKRCKQGLPAFRQSQPS 135
EAFCH NCS A +P+P G A ELRLFG +L RA CL+RCK+ LPAF+ P
Sbjct: 73 EAFCHANCSGPAPAAKPDPDGGRADEWACELRLFGRVLERAACLRRCKRTLPAFQVPYPP 132
Query: 136 REVLADFQRREPYKFLQFAYFKANNLPK 163
R++L DFQ R PY++L +A FKAN L K
Sbjct: 133 RQLLRDFQSRLPYQYLHYALFKANRLEK 160
>gi|27764882 leprecan-like 1 isoform a [Homo sapiens]
Length = 708
Score = 80.9 bits (198), Expect = 9e-16
Identities = 52/127 (40%), Positives = 65/127 (51%), Gaps = 5/127 (3%)
Query: 41 LMPLESAYRHALDKYSGEHWAESVGYLEISLRLHRLLRDSEAFCHRNCSAA-PQPEPAAG 99
L P + Y Y + +V LE +LR HR LR+ C R+C+A P P P G
Sbjct: 41 LQPFDLLYASGAAAYYSGDYERAVRDLEAALRSHRRLREIRTRCARHCAARHPLPPPPPG 100
Query: 100 LASYPELRLFGGLLRRAHCLKRCKQ---GLPAFRQSQPSREVLADFQRREPYKFLQFAYF 156
EL LF LL RA C + C+ G PA R + S +V +DFQRR PY +LQ AY
Sbjct: 101 EGPGAELPLFRSLLGRARCYRSCETQRLGGPASRH-RVSEDVRSDFQRRVPYNYLQRAYI 159
Query: 157 KANNLPK 163
K N L K
Sbjct: 160 KLNQLEK 166
>gi|186928835 leprecan 1 isoform 1 [Homo sapiens]
Length = 736
Score = 74.7 bits (182), Expect = 7e-14
Identities = 57/168 (33%), Positives = 77/168 (45%), Gaps = 20/168 (11%)
Query: 6 RGAAALLALLCVACALRAGRAQYERYSFRSFPRDELMPLESAYRHALDKYSGEHWAESVG 65
R L LL V A A +A+ E + +L+ + Y+ W V
Sbjct: 4 RALKLLTTLLAVVAA--ASQAEVESEAGWGMVTPDLL-----FAEGTAAYARGDWPGVVL 56
Query: 66 YLEISLRLHRLLRDSEAFCHRNCSA----------APQPEPAAGLASYPELRLFGGLLRR 115
+E +LR LR C C+A +P P A+G A+ +L FGGLLRR
Sbjct: 57 SMERALRSRAALRALRLRCRTQCAADFPWELDPDWSPSPAQASGAAALRDLSFFGGLLRR 116
Query: 116 AHCLKRCKQGLPAFRQSQPSREVLADFQRREPYKFLQFAYFKANNLPK 163
A CL+RC G PA S E+ +F++R PY +LQ AYFK N L K
Sbjct: 117 AACLRRC-LGPPAAHSL--SEEMELEFRKRSPYNYLQVAYFKINKLEK 161
Score = 33.1 bits (74), Expect = 0.22
Identities = 32/121 (26%), Positives = 46/121 (38%), Gaps = 5/121 (4%)
Query: 40 ELMPLESAYRHALDKYSGEHWAESVGYLEISLRLHRLLRDSEAFCHRNCSAAPQPEPAAG 99
E P +R + YS E E+V +LE +L+ + + + C C P
Sbjct: 201 ETQPHMQEFRLGVRLYSEEQPQEAVPHLEAALQEYFVAYEE---CRALCEG-PYDYDGYN 256
Query: 100 LASYPELRLFGGLLRRAHCLKRCKQGLPAFRQSQPSREVLADFQRREPYKFLQFAYFKAN 159
Y LF + + CKQ S PSRE + Y +LQFAY+
Sbjct: 257 YLEY-NADLFQAITDHYIQVLNCKQNCVTELASHPSREKPFEDFLPSHYNYLQFAYYNIG 315
Query: 160 N 160
N
Sbjct: 316 N 316
>gi|226371643 leprecan 1 isoform 2 [Homo sapiens]
Length = 697
Score = 74.7 bits (182), Expect = 7e-14
Identities = 57/168 (33%), Positives = 77/168 (45%), Gaps = 20/168 (11%)
Query: 6 RGAAALLALLCVACALRAGRAQYERYSFRSFPRDELMPLESAYRHALDKYSGEHWAESVG 65
R L LL V A A +A+ E + +L+ + Y+ W V
Sbjct: 4 RALKLLTTLLAVVAA--ASQAEVESEAGWGMVTPDLL-----FAEGTAAYARGDWPGVVL 56
Query: 66 YLEISLRLHRLLRDSEAFCHRNCSA----------APQPEPAAGLASYPELRLFGGLLRR 115
+E +LR LR C C+A +P P A+G A+ +L FGGLLRR
Sbjct: 57 SMERALRSRAALRALRLRCRTQCAADFPWELDPDWSPSPAQASGAAALRDLSFFGGLLRR 116
Query: 116 AHCLKRCKQGLPAFRQSQPSREVLADFQRREPYKFLQFAYFKANNLPK 163
A CL+RC G PA S E+ +F++R PY +LQ AYFK N L K
Sbjct: 117 AACLRRC-LGPPAAHSL--SEEMELEFRKRSPYNYLQVAYFKINKLEK 161
Score = 33.1 bits (74), Expect = 0.22
Identities = 32/121 (26%), Positives = 46/121 (38%), Gaps = 5/121 (4%)
Query: 40 ELMPLESAYRHALDKYSGEHWAESVGYLEISLRLHRLLRDSEAFCHRNCSAAPQPEPAAG 99
E P +R + YS E E+V +LE +L+ + + + C C P
Sbjct: 201 ETQPHMQEFRLGVRLYSEEQPQEAVPHLEAALQEYFVAYEE---CRALCEG-PYDYDGYN 256
Query: 100 LASYPELRLFGGLLRRAHCLKRCKQGLPAFRQSQPSREVLADFQRREPYKFLQFAYFKAN 159
Y LF + + CKQ S PSRE + Y +LQFAY+
Sbjct: 257 YLEY-NADLFQAITDHYIQVLNCKQNCVTELASHPSREKPFEDFLPSHYNYLQFAYYNIG 315
Query: 160 N 160
N
Sbjct: 316 N 316
>gi|28466983 leprecan-like 2 [Homo sapiens]
Length = 736
Score = 50.8 bits (120), Expect = 1e-06
Identities = 41/133 (30%), Positives = 54/133 (40%), Gaps = 22/133 (16%)
Query: 48 YRHALDKYSGEHWAESVGYLEISLRLHRLLRDSEAFCHRNCSAAP----------QPEPA 97
Y L Y+ WA +V L +LR L C +C+A P PEP
Sbjct: 41 YADGLRAYAAGAWAPAVALLREALRSQAALGRVRLDCGASCAADPGAALPAVLLGAPEPD 100
Query: 98 AGLASYP---ELRLFGGLLRRAHCLKRCKQ------GLPAFRQSQPSREVLADFQRREPY 148
+G E +L LRRA CL +C G R R+ F+RREPY
Sbjct: 101 SGPGPTQGSWERQLLRAALRRADCLTQCAARRLGPGGAARLRVGSALRDA---FRRREPY 157
Query: 149 KFLQFAYFKANNL 161
+LQ AY++ L
Sbjct: 158 NYLQRAYYQLKKL 170
>gi|108773804 Fraser syndrome 1 [Homo sapiens]
Length = 4011
Score = 32.3 bits (72), Expect = 0.38
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 5/42 (11%)
Query: 84 CHRNCSAAPQPEPAAGLASYPELRLFGGLLRRAHCLKRCKQG 125
CH +C++ P P+ A P L R+ HCL RC +G
Sbjct: 608 CHNSCASCSGPTPSHCTACSPPKAL-----RQGHCLPRCGEG 644
>gi|221554526 coiled-coil domain containing 42B [Homo sapiens]
Length = 308
Score = 31.2 bits (69), Expect = 0.84
Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 4/77 (5%)
Query: 71 LRLHRLLRDSEAFCHRNCSAAPQPEPAAGLASYPELRLFGGL--LRRAHC--LKRCKQGL 126
+R + L+DSEA +R A + AG LRL+ L LRR H +R K+
Sbjct: 82 IRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRLE 141
Query: 127 PAFRQSQPSREVLADFQ 143
P R + + E+L FQ
Sbjct: 142 PCARLLEQALELLPGFQ 158
>gi|4503327 cytochrome b5 reductase 3 isoform m [Homo sapiens]
Length = 301
Score = 30.8 bits (68), Expect = 1.1
Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 2/54 (3%)
Query: 155 YFKANNLPKCWDYKQPGNRETMI--HVQSPRRVIKLLKAGPPDCSSKGSLPRED 206
++ + P+ WDY Q E MI H+ P +L GPP LP D
Sbjct: 236 WYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLD 289
>gi|193794826 cytochrome b5 reductase 3 isoform s [Homo sapiens]
Length = 278
Score = 30.8 bits (68), Expect = 1.1
Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 2/54 (3%)
Query: 155 YFKANNLPKCWDYKQPGNRETMI--HVQSPRRVIKLLKAGPPDCSSKGSLPRED 206
++ + P+ WDY Q E MI H+ P +L GPP LP D
Sbjct: 213 WYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLD 266
>gi|6552328 cytochrome b5 reductase 3 isoform s [Homo sapiens]
Length = 278
Score = 30.8 bits (68), Expect = 1.1
Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 2/54 (3%)
Query: 155 YFKANNLPKCWDYKQPGNRETMI--HVQSPRRVIKLLKAGPPDCSSKGSLPRED 206
++ + P+ WDY Q E MI H+ P +L GPP LP D
Sbjct: 213 WYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLD 266
>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2a [Homo sapiens]
Length = 613
Score = 30.0 bits (66), Expect = 1.9
Identities = 15/37 (40%), Positives = 22/37 (59%), Gaps = 1/37 (2%)
Query: 188 LLKAGPPDCSSKGSLPREDACKTQIVLSWSHAAARSL 224
LL G C+S G + R+D CK ++ ++ A ARSL
Sbjct: 577 LLTTGDYTCASDGGI-RKDNCKEVVITGYTQAEARSL 612
>gi|239753555 PREDICTED: hypothetical protein XP_002345695 [Homo
sapiens]
Length = 258
Score = 29.6 bits (65), Expect = 2.5
Identities = 15/34 (44%), Positives = 20/34 (58%), Gaps = 1/34 (2%)
Query: 207 ACKTQIVLSWSHAAARSLLAAPTRPARPQRGGAR 240
AC+ + SW +A R+ AAP +RP RGG R
Sbjct: 91 ACRREEARSWPASATRAP-AAPPSASRPTRGGTR 123
>gi|115527106 vitelliform macular dystrophy 2-like 3 isoform 2 [Homo
sapiens]
Length = 455
Score = 29.3 bits (64), Expect = 3.2
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 6/67 (8%)
Query: 165 WDYKQPGNRETMIHVQSPRRVIKLLKAGP-PDCSSKGSLPREDACKTQIVLSWSHAAARS 223
WDY++ G+R +MI RRV + L A P + S R+ + + + + AR
Sbjct: 167 WDYEKHGHRHSMI-----RRVKRFLSAHEHPSSPRRRSYRRQTSDSSMFLPRDDLSPARD 221
Query: 224 LLAAPTR 230
LL P+R
Sbjct: 222 LLDVPSR 228
>gi|115527104 vitelliform macular dystrophy 2-like 3 isoform 1 [Homo
sapiens]
Length = 668
Score = 29.3 bits (64), Expect = 3.2
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 6/67 (8%)
Query: 165 WDYKQPGNRETMIHVQSPRRVIKLLKAGP-PDCSSKGSLPREDACKTQIVLSWSHAAARS 223
WDY++ G+R +MI RRV + L A P + S R+ + + + + AR
Sbjct: 380 WDYEKHGHRHSMI-----RRVKRFLSAHEHPSSPRRRSYRRQTSDSSMFLPRDDLSPARD 434
Query: 224 LLAAPTR 230
LL P+R
Sbjct: 435 LLDVPSR 441
>gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]
Length = 669
Score = 27.7 bits (60), Expect = 9.3
Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 8/55 (14%)
Query: 93 QPEPAAGLASYPELRLFGGLLRRAHCLKRCKQGLPAFRQSQPSREVLADFQRREP 147
QPEP+A L +P+ FG L R K LP+ +A F R P
Sbjct: 359 QPEPSAVLKRHPQPEFFGDLPR--------KPPLPSSASESSLPAAVAGFSSRHP 405
>gi|8923763 centaurin-alpha 2 protein [Homo sapiens]
Length = 381
Score = 27.7 bits (60), Expect = 9.3
Identities = 12/24 (50%), Positives = 15/24 (62%)
Query: 20 ALRAGRAQYERYSFRSFPRDELMP 43
ALRA R QY + +F P EL+P
Sbjct: 227 ALRAARLQYLKMAFPELPESELVP 250
>gi|63999355 chromosome 9 open reading frame 37 [Homo sapiens]
Length = 176
Score = 27.7 bits (60), Expect = 9.3
Identities = 18/73 (24%), Positives = 29/73 (39%), Gaps = 2/73 (2%)
Query: 169 QPGNRETMIHVQSPRRVIKLLKAGPPDCSSKGSLPREDACKTQIVLSWSHAAARSLLAAP 228
+P + + + +++P R P + P E C T+ LS R A
Sbjct: 68 EPSSPPSPLFLEAPSRQASQHHGASPGAGTSAGCPFEKCCSTEPCLSGLGDVGRG--EAA 125
Query: 229 TRPARPQRGGARG 241
+ ARP G +RG
Sbjct: 126 SLRARPGSGASRG 138
>gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]
Length = 904
Score = 27.7 bits (60), Expect = 9.3
Identities = 24/79 (30%), Positives = 31/79 (39%), Gaps = 23/79 (29%)
Query: 175 TMIHVQSPRRVIKLLKAGPPDCSSKGSLPREDACKTQIV----LSWSHAAARSLLAAP-- 228
T +HV+SP R P S P E + ++ + WS AA + AA
Sbjct: 312 TSVHVRSPAR---------PSESRLAPTPTEGKVRPRVTNSSPMGWSSAAPCTAAAASHP 362
Query: 229 --------TRPARPQRGGA 239
RPA PQ GGA
Sbjct: 363 AVPPSAPDPRPATPQGGGA 381
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.136 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,921,124
Number of Sequences: 37866
Number of extensions: 534331
Number of successful extensions: 1241
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1217
Number of HSP's gapped (non-prelim): 26
length of query: 241
length of database: 18,247,518
effective HSP length: 99
effective length of query: 142
effective length of database: 14,498,784
effective search space: 2058827328
effective search space used: 2058827328
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.