Search of human proteins with 118600967

Search of human proteins with 118600967

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|118600967 shroom family member 4 [Homo sapiens]
         (1493 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|118600967 shroom family member 4 [Homo sapiens]                   3055   0.0  
gi|4502175 apical protein of Xenopus-like [Homo sapiens]              250   8e-66
gi|203098098 shroom family member 3 protein [Homo sapiens]            247   7e-65
gi|31442420 shroom family member 1 [Homo sapiens]                     108   4e-23
gi|17975763 myelin transcription factor 1 [Homo sapiens]               71   9e-12
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    69   3e-11
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        63   2e-09
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]             63   2e-09
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    62   4e-09
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]              62   5e-09
gi|193083191 synaptopodin 2 isoform c [Homo sapiens]                   61   9e-09
gi|193083185 synaptopodin 2 isoform b [Homo sapiens]                   61   9e-09
gi|193083183 synaptopodin 2 isoform a [Homo sapiens]                   61   9e-09
gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]              60   2e-08
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]             60   2e-08
gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo ...    59   4e-08
gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]              59   4e-08
gi|55953110 retinoblastoma protein-binding zinc finger protein i...    59   5e-08
gi|20336260 retinoblastoma protein-binding zinc finger protein i...    59   5e-08
gi|20336258 retinoblastoma protein-binding zinc finger protein i...    59   5e-08
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     58   6e-08
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     58   6e-08
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    58   8e-08
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    58   8e-08
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    58   8e-08
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    58   8e-08
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    58   8e-08
gi|87298939 hypothetical protein LOC131831 [Homo sapiens]              57   1e-07
gi|33286444 mastermind-like 2 [Homo sapiens]                           57   1e-07
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof...    57   1e-07

>gi|118600967 shroom family member 4 [Homo sapiens]
          Length = 1493

 Score = 3055 bits (7919), Expect = 0.0
 Identities = 1493/1493 (100%), Positives = 1493/1493 (100%)

Query: 1    MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVN 60
            MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVN
Sbjct: 1    MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVN 60

Query: 61   INGTPLYGSRQEALILIKGSFRILKLIVRRRNAPVSRPHSWHVAKLLEGCPEAATTMHFP 120
            INGTPLYGSRQEALILIKGSFRILKLIVRRRNAPVSRPHSWHVAKLLEGCPEAATTMHFP
Sbjct: 61   INGTPLYGSRQEALILIKGSFRILKLIVRRRNAPVSRPHSWHVAKLLEGCPEAATTMHFP 120

Query: 121  SEAFSLSWHSGCNTSDVCVQWCPLSRHCSTEKSSSIGSMESLEQPGQATYESHLLPIDQN 180
            SEAFSLSWHSGCNTSDVCVQWCPLSRHCSTEKSSSIGSMESLEQPGQATYESHLLPIDQN
Sbjct: 121  SEAFSLSWHSGCNTSDVCVQWCPLSRHCSTEKSSSIGSMESLEQPGQATYESHLLPIDQN 180

Query: 181  MYPNQRDSAYSSFSASSNASDCALSLRPEEPASTDCIMQGPGPTKAPSGRPNVAETSGGS 240
            MYPNQRDSAYSSFSASSNASDCALSLRPEEPASTDCIMQGPGPTKAPSGRPNVAETSGGS
Sbjct: 181  MYPNQRDSAYSSFSASSNASDCALSLRPEEPASTDCIMQGPGPTKAPSGRPNVAETSGGS 240

Query: 241  RRTNGGHLTPSSQMSSRPQEGYQSGPAKAVRGPPQPPVRRDSLQASRAQLLNGEQRRASE 300
            RRTNGGHLTPSSQMSSRPQEGYQSGPAKAVRGPPQPPVRRDSLQASRAQLLNGEQRRASE
Sbjct: 241  RRTNGGHLTPSSQMSSRPQEGYQSGPAKAVRGPPQPPVRRDSLQASRAQLLNGEQRRASE 300

Query: 301  PVVPLPQKEKLSLEPVLPARNPNRFCCLSGHDQVTSEGHQNCEFSQPPESSQQGSEHLLM 360
            PVVPLPQKEKLSLEPVLPARNPNRFCCLSGHDQVTSEGHQNCEFSQPPESSQQGSEHLLM
Sbjct: 301  PVVPLPQKEKLSLEPVLPARNPNRFCCLSGHDQVTSEGHQNCEFSQPPESSQQGSEHLLM 360

Query: 361  QASTKAVGSPKACDRASSVDSNPLNEASAELAKASFGRPPHLIGPTGHRHSAPEQLLASH 420
            QASTKAVGSPKACDRASSVDSNPLNEASAELAKASFGRPPHLIGPTGHRHSAPEQLLASH
Sbjct: 361  QASTKAVGSPKACDRASSVDSNPLNEASAELAKASFGRPPHLIGPTGHRHSAPEQLLASH 420

Query: 421  LQHVHLDTRGSKGMELPPVQDGHQWTLSPLHSSHKGKKSPCPPTGGTHDQSSKERKTRQV 480
            LQHVHLDTRGSKGMELPPVQDGHQWTLSPLHSSHKGKKSPCPPTGGTHDQSSKERKTRQV
Sbjct: 421  LQHVHLDTRGSKGMELPPVQDGHQWTLSPLHSSHKGKKSPCPPTGGTHDQSSKERKTRQV 480

Query: 481  DDRSLVLGHQSQSSPPHGEADGHPSEKGFLDPNRTSRAASELANQQPSASGSLVQQATDC 540
            DDRSLVLGHQSQSSPPHGEADGHPSEKGFLDPNRTSRAASELANQQPSASGSLVQQATDC
Sbjct: 481  DDRSLVLGHQSQSSPPHGEADGHPSEKGFLDPNRTSRAASELANQQPSASGSLVQQATDC 540

Query: 541  SSTTKAASGTEAGEEGDSEPKECSRMGGRRSGGTRGRSIQNRRKSERFATNLRNEIQRRK 600
            SSTTKAASGTEAGEEGDSEPKECSRMGGRRSGGTRGRSIQNRRKSERFATNLRNEIQRRK
Sbjct: 541  SSTTKAASGTEAGEEGDSEPKECSRMGGRRSGGTRGRSIQNRRKSERFATNLRNEIQRRK 600

Query: 601  AQLQKSKGPLSQLCDTKEPVEETQEPPESPPLTASNTSLLSSCKKPPSPRDKLFNKSMML 660
            AQLQKSKGPLSQLCDTKEPVEETQEPPESPPLTASNTSLLSSCKKPPSPRDKLFNKSMML
Sbjct: 601  AQLQKSKGPLSQLCDTKEPVEETQEPPESPPLTASNTSLLSSCKKPPSPRDKLFNKSMML 660

Query: 661  RARSSECLSQAPESHESRTGLEGRISPGQRPGQSSLGLNTWWKAPDPSSSDPEKAHAHCG 720
            RARSSECLSQAPESHESRTGLEGRISPGQRPGQSSLGLNTWWKAPDPSSSDPEKAHAHCG
Sbjct: 661  RARSSECLSQAPESHESRTGLEGRISPGQRPGQSSLGLNTWWKAPDPSSSDPEKAHAHCG 720

Query: 721  VRGGHWRWSPEHNSQPLVAAAMEGPSNPGDNKELKASTAQAGEDAILLPFADRRKFFEES 780
            VRGGHWRWSPEHNSQPLVAAAMEGPSNPGDNKELKASTAQAGEDAILLPFADRRKFFEES
Sbjct: 721  VRGGHWRWSPEHNSQPLVAAAMEGPSNPGDNKELKASTAQAGEDAILLPFADRRKFFEES 780

Query: 781  SKSLSTSHLPGLTTHSNKTFTQRPKPIDQNFQPMSSSCRELRRHPMDQSYHSADQPYHAT 840
            SKSLSTSHLPGLTTHSNKTFTQRPKPIDQNFQPMSSSCRELRRHPMDQSYHSADQPYHAT
Sbjct: 781  SKSLSTSHLPGLTTHSNKTFTQRPKPIDQNFQPMSSSCRELRRHPMDQSYHSADQPYHAT 840

Query: 841  DQSYHSMSPLQSETPTYSECFASKGLENSMCCKPLHCGDFDYHRTCSYSCSVQGALVHDP 900
            DQSYHSMSPLQSETPTYSECFASKGLENSMCCKPLHCGDFDYHRTCSYSCSVQGALVHDP
Sbjct: 841  DQSYHSMSPLQSETPTYSECFASKGLENSMCCKPLHCGDFDYHRTCSYSCSVQGALVHDP 900

Query: 901  CIYCSGEICPALLKRNMMPNCYNCRCHHHQCIRCSVCYHNPQHSALEDSSLAPGNTWKPR 960
            CIYCSGEICPALLKRNMMPNCYNCRCHHHQCIRCSVCYHNPQHSALEDSSLAPGNTWKPR
Sbjct: 901  CIYCSGEICPALLKRNMMPNCYNCRCHHHQCIRCSVCYHNPQHSALEDSSLAPGNTWKPR 960

Query: 961  KLTVQEFPGDKWNPITGNRKTSQSGREMAHSKTSFSWATPFHPCLENPALDLSSYRAISS 1020
            KLTVQEFPGDKWNPITGNRKTSQSGREMAHSKTSFSWATPFHPCLENPALDLSSYRAISS
Sbjct: 961  KLTVQEFPGDKWNPITGNRKTSQSGREMAHSKTSFSWATPFHPCLENPALDLSSYRAISS 1020

Query: 1021 LDLLGDFKHALKKSEETSVYEEGSSLASMPHPLRSRAFSESHISLAPQSTRAWGQHRREL 1080
            LDLLGDFKHALKKSEETSVYEEGSSLASMPHPLRSRAFSESHISLAPQSTRAWGQHRREL
Sbjct: 1021 LDLLGDFKHALKKSEETSVYEEGSSLASMPHPLRSRAFSESHISLAPQSTRAWGQHRREL 1080

Query: 1081 FSKGDETQSDLLGARKKAFPPPRPPPPNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEE 1140
            FSKGDETQSDLLGARKKAFPPPRPPPPNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEE
Sbjct: 1081 FSKGDETQSDLLGARKKAFPPPRPPPPNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEE 1140

Query: 1141 EEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALNPEEVLEQPQPLSFGHLEGSRQGSQS 1200
            EEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALNPEEVLEQPQPLSFGHLEGSRQGSQS
Sbjct: 1141 EEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALNPEEVLEQPQPLSFGHLEGSRQGSQS 1200

Query: 1201 VPAEQESFALHSSDFLPPIRGHLGSQPEQAQPPCYYGIGGLWRTSGQEATESAKQEFQHF 1260
            VPAEQESFALHSSDFLPPIRGHLGSQPEQAQPPCYYGIGGLWRTSGQEATESAKQEFQHF
Sbjct: 1201 VPAEQESFALHSSDFLPPIRGHLGSQPEQAQPPCYYGIGGLWRTSGQEATESAKQEFQHF 1260

Query: 1261 SPPSGAPGIPTSYSAYYNISVAKAELLNKLKDQPEMAEIGLGEEEVDHELAQKKIQLIES 1320
            SPPSGAPGIPTSYSAYYNISVAKAELLNKLKDQPEMAEIGLGEEEVDHELAQKKIQLIES
Sbjct: 1261 SPPSGAPGIPTSYSAYYNISVAKAELLNKLKDQPEMAEIGLGEEEVDHELAQKKIQLIES 1320

Query: 1321 ISRKLSVLREAQRGLLEDINANSALGEEVEANLKAVCKSNEFEKYHLFVGDLDKVVNLLL 1380
            ISRKLSVLREAQRGLLEDINANSALGEEVEANLKAVCKSNEFEKYHLFVGDLDKVVNLLL
Sbjct: 1321 ISRKLSVLREAQRGLLEDINANSALGEEVEANLKAVCKSNEFEKYHLFVGDLDKVVNLLL 1380

Query: 1381 SLSGRLARVENALNSIDSEANQEKLVLIEKKQQLTGQLADAKELKEHVDRREKLVFGMVS 1440
            SLSGRLARVENALNSIDSEANQEKLVLIEKKQQLTGQLADAKELKEHVDRREKLVFGMVS
Sbjct: 1381 SLSGRLARVENALNSIDSEANQEKLVLIEKKQQLTGQLADAKELKEHVDRREKLVFGMVS 1440

Query: 1441 RYLPQDQLQDYQHFVKMKSALIIEQRELEEKIKLGEEQLKCLRESLLLGPSNF 1493
            RYLPQDQLQDYQHFVKMKSALIIEQRELEEKIKLGEEQLKCLRESLLLGPSNF
Sbjct: 1441 RYLPQDQLQDYQHFVKMKSALIIEQRELEEKIKLGEEQLKCLRESLLLGPSNF 1493


>gi|4502175 apical protein of Xenopus-like [Homo sapiens]
          Length = 1616

 Score =  250 bits (638), Expect = 8e-66
 Identities = 139/245 (56%), Positives = 179/245 (73%), Gaps = 17/245 (6%)

Query: 1249 ATESAKQEFQHFSPPSGAPGIPTSYS-----AYYNISVAKAELLNKLKDQPEMAEIGLGE 1303
            +TE  K+E          P +P + S      YY+ S  KAELL K+KD  E  E     
Sbjct: 1376 STEERKEE----------PSVPAAVSLATNSTYYSTSAPKAELLIKMKDLQEQQEHEEDS 1425

Query: 1304 -EEVDHELAQKKIQLIESISRKLSVLREAQRGLLEDINANSALGEEVEANLKAVCKSNEF 1362
              ++DH+L+ KK +LIESISRKL VLREA+  LLED+ AN+ LG EVEA +K VCK +EF
Sbjct: 1426 GSDLDHDLSVKKQELIESISRKLQVLREARESLLEDVQANTVLGAEVEAIVKGVCKPSEF 1485

Query: 1363 EKYHLFVGDLDKVVNLLLSLSGRLARVENALNSIDSEANQ-EKLVLIEKKQQLTGQLADA 1421
            +K+ +F+GDLDKVVNLLLSLSGRLARVENALN++D  A+  ++  L+EK++ L  Q  DA
Sbjct: 1486 DKFRMFIGDLDKVVNLLLSLSGRLARVENALNNLDDGASPGDRQSLLEKQRVLIQQHEDA 1545

Query: 1422 KELKEHVDRREKLVFGMVSRYLPQDQLQDYQHFVKMKSALIIEQRELEEKIKLGEEQLKC 1481
            KELKE++DRRE++VF +++ YL ++ L DY+HFVKMKSALIIEQRELE+KI LGEEQLKC
Sbjct: 1546 KELKENLDRRERIVFDILANYLSEESLADYEHFVKMKSALIIEQRELEDKIHLGEEQLKC 1605

Query: 1482 LRESL 1486
            L +SL
Sbjct: 1606 LLDSL 1610



 Score =  192 bits (489), Expect = 2e-48
 Identities = 191/644 (29%), Positives = 280/644 (43%), Gaps = 64/644 (9%)

Query: 11  VPVQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVNINGTPLYGSR 70
           V VQL GGAPWGFTLKGG EH EPL ++KIE+G KAA   K+  GDE+V IN   L G R
Sbjct: 27  VEVQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGFR 86

Query: 71  QEALILIKGSFRILKLIVRRRNAPVSRPHSWHVAKLLEGCPEAATTMHFPSEAFSLSW-- 128
           QEA+ L+KGS + LKL+V+RR+    RPHSWH  K  +  PE A +  F S +   SW  
Sbjct: 87  QEAICLVKGSHKTLKLVVKRRSELGWRPHSWHATKFSDSHPELAAS-PFTSTSGCPSWSG 145

Query: 129 --HSGCNTSDVCVQWCPLSRHCSTEKSSSIGSMESLEQP-GQATYESHLLPIDQNMYPNQ 185
             H+  ++ D+   W   +   + +  SS+GS++SL+ P  + +       ID     ++
Sbjct: 146 RHHASSSSHDLSSSWEQTNLQRTLDHFSSLGSVDSLDHPSSRLSVAKSNSSIDHLGSHSK 205

Query: 186 RDSAYSSFSASSNASDCALSLRPEEPASTDCIMQGPGPTKAP--SGRPNVA--ETSGGSR 241
           RDSAY SFS SS+  D  LS    + +S + I+   G  +AP   GR   A  +  G   
Sbjct: 206 RDSAYGSFSTSSSTPDHTLS--KADTSSAENILYTVGLWEAPRQGGRQAQAAGDPQGSEE 263

Query: 242 RTNGGHLTPSSQMSSRPQEGYQSGPAKAVRG---------------------PPQPPVRR 280
           + +             P+  Y + P  A  G                     PP PP+R 
Sbjct: 264 KLSCFPPRVPGDSGKGPRPEYNAEPKLAAPGRSNFGPVWYVPDKKKAPSSPPPPPPPLRS 323

Query: 281 DSLQAS----RAQLLNGEQRRASEPVVPLPQKE-KLSLEPVLPAR-----NPNRFCCLSG 330
           DS  A+    +AQ     +  A++    L Q + +    P L  R     +P      SG
Sbjct: 324 DSFAATKSHEKAQGPVFSEAAAAQHFTALAQAQPRGDRRPELTDRPWRSAHPGSLGKGSG 383

Query: 331 HDQVTSEGHQNCEFSQPPESSQQGSEHLLMQASTKAVGSPKACDRASSVDSNPLNEASAE 390
                 E H +  +   P S    S  L    S+  V  P++     S    PL    + 
Sbjct: 384 GPGCPQEAHADGSW---PPSKDGASSRLQASLSSSDVRFPQS---PHSGRHPPLYSDHSP 437

Query: 391 LAKASFGRPPHLIGPTGHRHSAPEQL--LASHLQHVHLDTRGSKGMELPPVQDGHQWT-L 447
           L   S G+ P   G    ++ +P Q+  L+S  Q +    +G +      +Q    W   
Sbjct: 438 LCADSLGQEP---GAASFQNDSPPQVRGLSSCDQKLGSGWQGPRPCVQGDLQAAQLWAGC 494

Query: 448 SPLHSSHKGKKSPCPPTGGTHDQSSKERKTRQVDDRSLVLGHQSQSSPPHGEADGHPSEK 507
            P  ++    +S  PPT G   +    +     D R        +  P    A+G     
Sbjct: 495 WPSDTALGALESLPPPTVGQSPRHHLPQPEGPPDAR-----ETGRCYPLDKGAEG--CSA 547

Query: 508 GFLDPNRTSRAASELANQQPSASGSLVQQATDCSSTTKAASGTEAGEEGDSEPKECSRMG 567
           G  +P R SRA  E A+Q+ +AS +     +      +        +EG   P+      
Sbjct: 548 GAQEPPRASRA--EKASQRLAASITWADGESSRICPQETPLLHSLTQEGKRRPESSPEDS 605

Query: 568 GRRSGGTRGRSIQNRRKSERFATNLRNEIQRRKAQLQKSKGPLS 611
             R         +  R+S+RFAT LRNEIQ  +A+LQKS+  ++
Sbjct: 606 ATRPPPFDAHVGKPTRRSDRFATTLRNEIQMHRAKLQKSRSTVA 649


>gi|203098098 shroom family member 3 protein [Homo sapiens]
          Length = 1996

 Score =  247 bits (630), Expect = 7e-65
 Identities = 130/220 (59%), Positives = 173/220 (78%), Gaps = 8/220 (3%)

Query: 1275 AYYNISVAKAELLNKLKDQPEMAEIGLGEEEVDHELAQKKIQLIESISRKLSVLREAQRG 1334
            AYY++S  KAELLNK+K+ P  AE+   EE+ D  + +KK +LI S++ KL  L+EA+  
Sbjct: 1748 AYYSVSAPKAELLNKIKEMP--AEVNEEEEQAD--VNEKKAELIGSLTHKLETLQEAKGS 1803

Query: 1335 LLEDINANSALGEEVEANLKAVCKSNEFEKYHLFVGDLDKVVNLLLSLSGRLARVENALN 1394
            LL DI  N+ALGEEVEA +  +CK NEF+KY +F+GDLDKVVNLLLSLSGRLARVEN L+
Sbjct: 1804 LLTDIKLNNALGEEVEALISELCKPNEFDKYRMFIGDLDKVVNLLLSLSGRLARVENVLS 1863

Query: 1395 SIDSEA-NQEKLVLIEKKQQLTGQLADAKELKEHVDRREKLVFGMVSRYLPQDQLQDYQH 1453
             +  +A N+E+  L EK++ L GQ  DA+ELKE++DRRE++V G+++ YL ++QLQDYQH
Sbjct: 1864 GLGEDASNEERSSLYEKRKILAGQHEDARELKENLDRRERVVLGILANYLSEEQLQDYQH 1923

Query: 1454 FVKMKSALIIEQRELEEKIKLGEEQLKCLRESLLLGPSNF 1493
            FVKMKS L+IEQR+L++KIKLG+EQ+KCL ESL   PS+F
Sbjct: 1924 FVKMKSTLLIEQRKLDDKIKLGQEQVKCLLESL---PSDF 1960



 Score =  144 bits (363), Expect = 6e-34
 Identities = 100/248 (40%), Positives = 131/248 (52%), Gaps = 57/248 (22%)

Query: 6   GSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKA-ALSQKMRTGDELVNINGT 64
           G + Y+   L+GGAPWGFTLKGGLEH EPL +SK+E+GGKA  LS K++ GDE+V+IN  
Sbjct: 23  GRYIYLEAFLEGGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHINEV 82

Query: 65  PLYGSRQEALILIKGSFRILKLIVR----------------------------------- 89
            L  SR+EA+ L+KGS++ L+L+VR                                   
Sbjct: 83  TLSSSRKEAVSLVKGSYKTLRLVVRRDVCTDPGHADTGASNFVSPEHLTSGPQHRKAAWS 142

Query: 90  ---------RRNAPVSRPHSWHVAKLLEGCPEAA---TTMHFPSEAFSLSWHSGCNTSDV 137
                    RR+ P  RPHSWH  K  E  P+A+    +       +  S+HS  +TSD+
Sbjct: 143 GGVKLRLKHRRSEPAGRPHSWHTTKSGEKQPDASMMQISQGMIGPPWHQSYHSSSSTSDL 202

Query: 138 CVQWCPLSRHCSTEKSSSIGSMESLEQPGQATYESHLLP------IDQ-NMYPNQRDSAY 190
                   R  S ++ SS GSMESLE P  A    HL P      IDQ + + N+RDSAY
Sbjct: 203 SNYDHAYLRR-SPDQCSSQGSMESLE-PSGAYPPCHLSPAKSTGSIDQLSHFHNKRDSAY 260

Query: 191 SSFSASSN 198
           SSFS SS+
Sbjct: 261 SSFSTSSS 268



 Score = 32.3 bits (72), Expect = 3.5
 Identities = 38/160 (23%), Positives = 56/160 (35%), Gaps = 32/160 (20%)

Query: 171  ESHLLPIDQNMYPNQRDSAYSSFSASSNASDCALSLRPEEPASTDCIMQGPGPTKAPSGR 230
            +  +LP+  ++ P    S   +   SS  S+C  +L  +  AS           + P  R
Sbjct: 1285 QEEMLPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQAS-----------RTPCPR 1333

Query: 231  PNVAETSGGSRRTNGGHLTP-SSQMSSRPQEGYQSGPAKAVRGPPQPPVRRDSLQASRAQ 289
            P +A T G    T    LTP  + + S    GY S   +  R  P PP     +  S   
Sbjct: 1334 PPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGR-QPLPPYTPAMMHRSNGH 1392

Query: 290  LL-------------------NGEQRRASEPVVPLPQKEK 310
             L                    G ++R S P  P P + K
Sbjct: 1393 TLTQPPGPRGCEGDGPEHGVEEGTRKRVSLPQWPPPSRAK 1432


>gi|31442420 shroom family member 1 [Homo sapiens]
          Length = 847

 Score =  108 bits (270), Expect = 4e-23
 Identities = 67/197 (34%), Positives = 115/197 (58%), Gaps = 12/197 (6%)

Query: 1292 DQPEMAEIGLGEEEVDHELAQKKIQLIESISRKLSVLREAQRGLLEDINANSALGEEVEA 1351
            DQP     G G    ++ +  KK++L   + + L  L   Q  L  +  A +     +EA
Sbjct: 633  DQP----CGQGLPAPNNSIQGKKVELAARLQKMLQDLHTEQERLQGEAQAWARRQAALEA 688

Query: 1352 NLKAVCKSNEFEKYHLFVGDLDKVVNLLLSLSGRLARVENALN--SIDSEANQEKLVLIE 1409
             ++  C   E E++  F+ DL++V+ LLL L  RLARV  AL   + DS+ ++++L L++
Sbjct: 689  AVRQACAPQELERFSRFMADLERVLGLLLLLGSRLARVRRALARAASDSDPDEQRLRLLQ 748

Query: 1410 KKQQLTGQLADAKELKEHVDRREKLVFGMVSRYLPQDQLQDYQHFVKMKSALIIEQRELE 1469
            ++++      DAKELKEHV RRE+ V  ++ R LP ++L+ Y   +  K+A++ +QR L+
Sbjct: 749  RQEE------DAKELKEHVARRERAVREVLVRALPVEELRVYCALLAGKAAVLAQQRNLD 802

Query: 1470 EKIKLGEEQLKCLRESL 1486
            E+I+L ++QL  +R+ L
Sbjct: 803  ERIRLLQDQLDAIRDDL 819



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 70/266 (26%), Positives = 96/266 (36%), Gaps = 45/266 (16%)

Query: 159 MESLEQPG-QATYESHLLPIDQNMYPNQRDSAYSSFSASSNASDCALSLRPEEPAS---- 213
           ME+L   G +A+  S    +D      + DSAYSSFSA+S   +     R + P +    
Sbjct: 1   MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPE----PRTQSPGTDLLP 56

Query: 214 ------TDCIMQGPGPT-------KAPSGRPNVAETSGGSRRTNGGHLTPSSQMSS---R 257
                    +  GPGP         +P  RP VA  SG       G   P ++ ++    
Sbjct: 57  YLDWDYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLY 116

Query: 258 PQEGYQSGPAKAVRGPPQPPVRRDSLQASRAQLLNGEQRRASEPVVPLPQKEKLS----L 313
                    A+AV  PP PP  R    A+  Q L G QRR         ++ ++S    L
Sbjct: 117 ALAAEAEAAAQAVE-PPSPPASR----AAYRQRLQGAQRRVLRETSFQRKELRMSLPARL 171

Query: 314 EPVLPARNPNRFCCLSGHDQVTSEGHQNCE----FSQPPESSQQGSEHLLMQASTKAVGS 369
            P +PAR P      + H +  S  H   E     S+ P     G   L  Q        
Sbjct: 172 RPTVPARPP------ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSE 225

Query: 370 PKACDRASSVDSNPLNEASAELAKAS 395
           P   DR       P  E   E   +S
Sbjct: 226 PGKLDRVGR-GGGPARECLGEACSSS 250


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 70.9 bits (172), Expect = 9e-12
 Identities = 34/69 (49%), Positives = 49/69 (71%), Gaps = 2/69 (2%)

Query: 1119 QQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALNPEE 1178
            ++++++ ++++++EEEEEEEEEEEEEEEEEEEE EEEEE  P   F  +TS + A    E
Sbjct: 268  EEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPE 327

Query: 1179 VL--EQPQP 1185
            +   E P P
Sbjct: 328  LRGPESPSP 336



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 28/47 (59%), Positives = 37/47 (78%), Gaps = 5/47 (10%)

Query: 1117 AAQQQKQQQQ-----QQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEE 1158
            AA ++  +Q+     +++ +EEEEEEEEEEE+EEEEEEEE EEEEEE
Sbjct: 243  AASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEE 289



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 31/81 (38%), Positives = 41/81 (50%)

Query: 1122 KQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALNPEEVLE 1181
            ++  +Q+     EEE+EEEEEEEEEEEE+E EEEEEE   +    E         EE  E
Sbjct: 246  EESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305

Query: 1182 QPQPLSFGHLEGSRQGSQSVP 1202
            +  P      + S   +Q  P
Sbjct: 306  EAAPDVIFQEDTSHTSAQKAP 326



 Score = 39.7 bits (91), Expect = 0.022
 Identities = 34/120 (28%), Positives = 51/120 (42%), Gaps = 15/120 (12%)

Query: 1119 QQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALNPEE 1178
            Q  +    ++  +++     EEE+EEEEEEEEE EE+EEE   +    E         EE
Sbjct: 238  QSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEE---------EE 288

Query: 1179 VLEQPQPLSFGHLEGSRQGSQSVPAEQESFALHSSDFLPPIRGHLGSQPEQAQPPCYYGI 1238
              E+ +       E   + +  V   QE  +  S+   P +RG     PE   P   Y +
Sbjct: 289  EEEEEEEEEEEEEEEEEEAAPDV-IFQEDTSHTSAQKAPELRG-----PESPSPKPEYSV 342


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 36/100 (36%), Positives = 61/100 (61%), Gaps = 5/100 (5%)

Query: 1068 QSTRAWGQHRRELFS-KGDETQSDL-LGARKKAFPPPRPPPPNWEKYRLFRAAQQQKQQQ 1125
            +    W +  +E+ S + +  QS   + ++ K    P   P   E+ +L   +++  +++
Sbjct: 1013 EQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEE 1072

Query: 1126 QQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEEL---PPQ 1162
            ++++ +EEEEEEEEEEE+EEEEEEEE EEEEE +   PP+
Sbjct: 1073 EEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPR 1112



 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 42/136 (30%), Positives = 57/136 (41%), Gaps = 29/136 (21%)

Query: 1121 QKQQQQQQKQQEEEEEEEEEEEEEEEEEEEE-------------AEEEEEELPPQYFSSE 1167
            +K +    K +EEEEEEEEEEEEEEEEE EE             A+ +E+E P      E
Sbjct: 1341 EKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKE 1400

Query: 1168 TSGSCALNPEEVLEQPQPL----------SFGHLEGSRQGSQSVPAEQESFALHSSD-FL 1216
             S     + EE  E  +P              H+E +    + +P E     L + + FL
Sbjct: 1401 DSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFL 1460

Query: 1217 PPIRGHLGSQPEQAQP 1232
                  L  QP  + P
Sbjct: 1461 -----DLNVQPGHSNP 1471



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 34/112 (30%), Positives = 51/112 (45%), Gaps = 12/112 (10%)

Query: 1107 PNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSS 1166
            P  E  R    A         +K +++  + EEEEEEEEEEEEEE EEE EE        
Sbjct: 1320 PQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEE-------E 1372

Query: 1167 ETSGSCALNPE----EVLEQPQPLSFGHLEGSRQGSQSVPAEQESFALHSSD 1214
            E  G+   +P+    +  E+P+ +S    + +R        E++    H+ D
Sbjct: 1373 EGGGNVEKDPDGAKSQEKEEPE-ISTEKEDSARLDDHEEEEEEDEEPSHNED 1423



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 19/49 (38%), Positives = 24/49 (48%)

Query: 1137 EEEEEEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALNPEEVLEQPQP 1185
            E  +E  EEEEEEE+ EEEEEE   +    E         EE ++   P
Sbjct: 1063 ELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPP 1111


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 36/89 (40%), Positives = 51/89 (57%), Gaps = 17/89 (19%)

Query: 1119 QQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALNPEE 1178
            Q Q   +++++++EE+EEEEEE+EEEEEEEEEE EEEEEE                  EE
Sbjct: 726  QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEE-----------------EEE 768

Query: 1179 VLEQPQPLSFGHLEGSRQGSQSVPAEQES 1207
              E    ++ G + G R GS S  +E+ +
Sbjct: 769  EEEAAAAVALGEVLGPRSGSSSEGSERST 797



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 28/76 (36%), Positives = 44/76 (57%)

Query: 1091 LLGARKKAFPPPRPPPPNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEE 1150
            LL   +    P +P     E+       ++++++ ++++++EEEEEEEEEEEEEEEEE  
Sbjct: 714  LLTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAA 773

Query: 1151 EAEEEEEELPPQYFSS 1166
             A    E L P+  SS
Sbjct: 774  AAVALGEVLGPRSGSS 789



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 26/70 (37%), Positives = 41/70 (58%)

Query: 1102 PRPPPPNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPP 1161
            P  P  N ++        ++++++ +++++EEEEEEEEEEEEEEEEEE  A     E+  
Sbjct: 724  PVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLG 783

Query: 1162 QYFSSETSGS 1171
                S + GS
Sbjct: 784  PRSGSSSEGS 793



 Score = 31.6 bits (70), Expect = 6.0
 Identities = 74/350 (21%), Positives = 112/350 (32%), Gaps = 46/350 (13%)

Query: 226  APSGRPNVAETSGGSRRTNGGHLTPSSQMSSRPQEGYQSGPAKAVRGPPQPPVRRDSLQA 285
            A SG P    +   +     G   P+      P    +  P K     P+      S   
Sbjct: 997  ALSGAPRETPSEMATNSLPNG---PALADGPAPVSPLEPSPEKVATISPRRHAMPGSRPR 1053

Query: 286  SRAQLLNGEQRRASEPVVPLPQKEKLS--------LEPVLPARNPNRFC--CLSGHDQVT 335
            SR  +L  E+   SEP   L  KE+ S        L  ++  +   R      SG    +
Sbjct: 1054 SRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQQDLARLVMEKRQGRLLLRLASGASSSS 1113

Query: 336  SEGHQNCEFSQPPESSQQGSEHLLMQASTKAVGSPKACDRASSVDSN---------PLNE 386
            SE  +    +     S++ +      AS  A   P+   RA++  S          P+  
Sbjct: 1114 SEEQRRASETLSGTGSEEDT-----PASEPAAALPRKSGRAAATRSRIPRPIGLRMPMPV 1168

Query: 387  ASAELAKASFGRPPHLIGPTGHRHSAPEQLLASHLQHVHLDTRGSKGMELPPVQDGHQWT 446
            A+ + A  S G  P L           +  + S LQ +      +   +L P Q   +  
Sbjct: 1169 AAQQPASRSHGAAPAL-----------DTAITSRLQ-LQTPPGSATAADLRPKQPPGR-G 1215

Query: 447  LSPLHSSHKGKKSPCPPTGGTHDQSSKERKTRQVDDRSLVLGHQSQSSPPHGEADGHPSE 506
            L P   +  G + P P +      +S  R       RS  L  +   SP H    G P  
Sbjct: 1216 LGP-GRAQAGARPPAPRSPRLPASTSAARNA-SASPRSQSLSRRESPSPSHQARPGVPPP 1273

Query: 507  KGFLDPNRTSRAASELANQQPSASGSLVQQATDCSSTTKAASGTEAGEEG 556
            +G                 +    G L  Q     +TTK  +G   G  G
Sbjct: 1274 RGVPPARAQPDGTPSPGGSKKGPRGKLQAQ----RATTKGRAGGAEGRAG 1319


>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
          Length = 596

 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 56/166 (33%), Positives = 80/166 (48%), Gaps = 10/166 (6%)

Query: 13  VQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVNINGTPLYG-SRQ 71
           V L G APWGF L+GG +   PLT+S ++DGGKAA    +R GD +++I+G    G +  
Sbjct: 6   VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAA-QANVRIGDVVLSIDGINAQGMTHL 64

Query: 72  EALILIKGSFRILKLIVRRRNAPVSRPHSWHVAKLLEGCPEAATTMHFPSEAFSLSWHSG 131
           EA   IKG    L + ++R +A   +P    V K   G P+       P    S +    
Sbjct: 65  EAQNKIKGCTGSLNMTLQRASA-APKPEPVPVQK---GEPKEVVK---PVPITSPAVSKV 117

Query: 132 CNTSDVCVQWCPLS-RHCSTEKSSSIGSMESLEQPGQATYESHLLP 176
            +T+++     P      S+ K +SI S  S   P  AT  SH  P
Sbjct: 118 TSTNNMAYNKAPRPFGSVSSPKVTSIPSPSSAFTPAHATTSSHASP 163



 Score = 31.2 bits (69), Expect = 7.8
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 12/75 (16%)

Query: 792 LTTHSNKTFTQRPKPIDQNFQPMSSSCRELRRHPMDQSYHSADQPYHATDQSYHSMSPLQ 851
           +T+ +N  + + P+P      P  +S           S  SA  P HAT  S+ S SP+ 
Sbjct: 117 VTSTNNMAYNKAPRPFGSVSSPKVTSI---------PSPSSAFTPAHATTSSHASPSPVA 167

Query: 852 SETPTYSECFASKGL 866
           + TP     FA+ GL
Sbjct: 168 AVTP---PLFAASGL 179


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 43/103 (41%), Positives = 52/103 (50%), Gaps = 12/103 (11%)

Query: 1131 QEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALNPEEVLEQPQPLSFGH 1190
            +EEEEEEEEEEEEEEEEEEEE  EEEEE   +YF  E         EE  E+     F  
Sbjct: 888  EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEE------EEEEEFEE----EFEE 937

Query: 1191 LEGSRQGSQSVPAEQESFALHSSDFLPPIRGHLGSQPEQAQPP 1233
             EG  +  +    E+E   L   + L    G  G + E+  PP
Sbjct: 938  EEGELEEEEEEEDEEEEEELEEVEDLE--FGTAGGEVEEGAPP 978



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 45/141 (31%), Positives = 64/141 (45%), Gaps = 20/141 (14%)

Query: 1105 PPPNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEE------EEAEEEEEE 1158
            PP   E   +       ++++++++++EEEEEEEEEEE+ EEEEE      EE EEEEEE
Sbjct: 871  PPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEE 930

Query: 1159 LPPQYFS-----SETSGSCALNPEEVLEQPQPLSFGHLEGS-RQGSQSVPAEQESFALHS 1212
               ++        E         EE LE+ + L FG   G   +G+   P    +     
Sbjct: 931  FEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPA----- 985

Query: 1213 SDFLPPIRGHLGSQPEQAQPP 1233
               LPP       QPE    P
Sbjct: 986  ---LPPPESPPKVQPEPEPEP 1003


>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
          Length = 587

 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 34/77 (44%), Positives = 45/77 (58%), Gaps = 8/77 (10%)

Query: 1117 AAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSETSGSCAL-- 1174
            A+    + ++++++ EEEEEE EEEEEE+EEEEEE EEEEEE P Q    E S + +   
Sbjct: 355  ASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKI 414

Query: 1175 ------NPEEVLEQPQP 1185
                   P  VL  P P
Sbjct: 415  LDPNTGEPAPVLSSPPP 431


>gi|193083191 synaptopodin 2 isoform c [Homo sapiens]
          Length = 1109

 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 32/92 (34%), Positives = 57/92 (61%), Gaps = 2/92 (2%)

Query: 6  GSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVNINGTP 65
          G+  ++ + + GGAPWGF L+GG E  +PL V+KI +  KA+    +  GDE+V+ING P
Sbjct: 2  GTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKAS-GSGLCEGDEVVSINGNP 60

Query: 66 LYG-SRQEALILIKGSFRILKLIVRRRNAPVS 96
              +  E + L++     L+++++R ++ +S
Sbjct: 61 CADLTYPEVIKLMESITDSLQMLIKRPSSGIS 92


>gi|193083185 synaptopodin 2 isoform b [Homo sapiens]
          Length = 1093

 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 32/92 (34%), Positives = 57/92 (61%), Gaps = 2/92 (2%)

Query: 6  GSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVNINGTP 65
          G+  ++ + + GGAPWGF L+GG E  +PL V+KI +  KA+    +  GDE+V+ING P
Sbjct: 2  GTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKAS-GSGLCEGDEVVSINGNP 60

Query: 66 LYG-SRQEALILIKGSFRILKLIVRRRNAPVS 96
              +  E + L++     L+++++R ++ +S
Sbjct: 61 CADLTYPEVIKLMESITDSLQMLIKRPSSGIS 92


>gi|193083183 synaptopodin 2 isoform a [Homo sapiens]
          Length = 1261

 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 32/92 (34%), Positives = 57/92 (61%), Gaps = 2/92 (2%)

Query: 6  GSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVNINGTP 65
          G+  ++ + + GGAPWGF L+GG E  +PL V+KI +  KA+    +  GDE+V+ING P
Sbjct: 2  GTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKAS-GSGLCEGDEVVSINGNP 60

Query: 66 LYG-SRQEALILIKGSFRILKLIVRRRNAPVS 96
              +  E + L++     L+++++R ++ +S
Sbjct: 61 CADLTYPEVIKLMESITDSLQMLIKRPSSGIS 92


>gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]
          Length = 234

 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 38/94 (40%), Positives = 54/94 (57%), Gaps = 9/94 (9%)

Query: 13 VQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVNINGTPLYG-SRQ 71
          V L G APWGF L+GG +   PLT+S ++DGGKAA    +R GD +++I+G    G +  
Sbjct: 6  VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAA-QANVRIGDVVLSIDGINAQGMTHL 64

Query: 72 EALILIKGSFRILKLIVRRRNA-------PVSRP 98
          EA   IKG    L + ++R +A       PV +P
Sbjct: 65 EAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKP 98


>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
          Length = 487

 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 38/94 (40%), Positives = 54/94 (57%), Gaps = 9/94 (9%)

Query: 13 VQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVNINGTPLYG-SRQ 71
          V L G APWGF L+GG +   PLT+S ++DGGKAA    +R GD +++I+G    G +  
Sbjct: 6  VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAA-QANVRIGDVVLSIDGINAQGMTHL 64

Query: 72 EALILIKGSFRILKLIVRRRNA-------PVSRP 98
          EA   IKG    L + ++R +A       PV +P
Sbjct: 65 EAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKP 98


>gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo
            sapiens]
          Length = 142

 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 26/44 (59%), Positives = 40/44 (90%)

Query: 1116 RAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEEL 1159
            R  +++++++++ K++E+EEE+EEEEEEEEEEEEEE EEEEEE+
Sbjct: 78   REEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEV 121



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 26/47 (55%), Positives = 39/47 (82%)

Query: 1110 EKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEE 1156
            E+ R     +++K+++ +++++EEE+EEEEEEEEEEEEEEEE EEEE
Sbjct: 74   EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 27/61 (44%), Positives = 43/61 (70%)

Query: 1116 RAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALN 1175
            R  +++++ ++++K++E+EEEEEEEEEEEEEEEEEE EE    L  +   +ET     ++
Sbjct: 82   RREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLIS 141

Query: 1176 P 1176
            P
Sbjct: 142  P 142



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 24/43 (55%), Positives = 38/43 (88%)

Query: 1116 RAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEE 1158
            R  ++++++++++ ++ E+EEE+EEEEEEEEEEEEE EEEEEE
Sbjct: 77   RREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 25/49 (51%), Positives = 40/49 (81%)

Query: 1110 EKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEE 1158
            EK R  +  +++++++++++ +  E+EEE+EEEEEEEEEEEE EEEEEE
Sbjct: 70   EKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEE 118



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 27/59 (45%), Positives = 42/59 (71%)

Query: 1110 EKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSET 1168
            E+ R     +++K++++++++ +  E+EEE+EEEEEEEEEEE EEEEEE     FS  T
Sbjct: 69   EEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLAT 127



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 27/69 (39%), Positives = 44/69 (63%), Gaps = 6/69 (8%)

Query: 1116 RAAQQQKQQQQQQKQQEEEEEEEEE------EEEEEEEEEEEAEEEEEELPPQYFSSETS 1169
            R +Q+++++++++K++EE+  EE+       E+EEE+EEEEE EEEEEE   +    E S
Sbjct: 63   RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122

Query: 1170 GSCALNPEE 1178
             S A    E
Sbjct: 123  FSLATRERE 131



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 23/55 (41%), Positives = 38/55 (69%), Gaps = 5/55 (9%)

Query: 1110 EKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEE-----EEEEEEAEEEEEEL 1159
            EK R  +  +++++++++++++EEEEEEEEEEEEEE        E E E EE+ L
Sbjct: 85   EKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRL 139



 Score = 37.4 bits (85), Expect = 0.11
 Identities = 14/42 (33%), Positives = 30/42 (71%)

Query: 1117 AAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEE 1158
            A + Q++++++++++  EE+  EE+  E +  E+E E+EEEE
Sbjct: 62   ARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEE 103



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 14/53 (26%), Positives = 33/53 (62%)

Query: 1106 PPNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEE 1158
            PP         +A++ +++++++++++  EE+  EE+  E +  E+ EE+EEE
Sbjct: 50   PPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEE 102


>gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]
          Length = 214

 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 35/82 (42%), Positives = 50/82 (60%), Gaps = 2/82 (2%)

Query: 13 VQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVNINGTPLYG-SRQ 71
          V L G APWGF L+GG +   PLT+S ++DGGKAA    +R GD +++I+G    G +  
Sbjct: 6  VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAA-QANVRIGDVVLSIDGINAQGMTHL 64

Query: 72 EALILIKGSFRILKLIVRRRNA 93
          EA   IKG    L + ++R +A
Sbjct: 65 EAQNKIKGCTGSLNMTLQRASA 86


>gi|55953110 retinoblastoma protein-binding zinc finger protein
            isoform c [Homo sapiens]
          Length = 1481

 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 10/117 (8%)

Query: 1094 ARKKAFPPPRPPPPNWEKY-----RLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEE 1148
            A ++  P    P P WE       RL  AA +     +++  +EEEEE+EEEEE+++++E
Sbjct: 30   ASQEVPPELATPAPAWEPQPEPDERLEAAACEVNDLGEEE--EEEEEEDEEEEEDDDDDE 87

Query: 1149 EEEAEEEEEELPPQYFSSETSGSCALNPEEVLEQPQPLSFGHLEGSRQGSQSVPAEQ 1205
             E+  EEE  +P +    E    C   PE++LE+P+  S   LE     S+  PA Q
Sbjct: 88   LEDEGEEEASMPNENSVKEPEIRCDEKPEDLLEEPKTTSEETLEDC---SEVTPAMQ 141


>gi|20336260 retinoblastoma protein-binding zinc finger protein
            isoform b [Homo sapiens]
          Length = 1682

 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 10/117 (8%)

Query: 1094 ARKKAFPPPRPPPPNWEKY-----RLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEE 1148
            A ++  P    P P WE       RL  AA +     +++  +EEEEE+EEEEE+++++E
Sbjct: 231  ASQEVPPELATPAPAWEPQPEPDERLEAAACEVNDLGEEE--EEEEEEDEEEEEDDDDDE 288

Query: 1149 EEEAEEEEEELPPQYFSSETSGSCALNPEEVLEQPQPLSFGHLEGSRQGSQSVPAEQ 1205
             E+  EEE  +P +    E    C   PE++LE+P+  S   LE     S+  PA Q
Sbjct: 289  LEDEGEEEASMPNENSVKEPEIRCDEKPEDLLEEPKTTSEETLEDC---SEVTPAMQ 342


>gi|20336258 retinoblastoma protein-binding zinc finger protein
            isoform a [Homo sapiens]
          Length = 1718

 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 10/117 (8%)

Query: 1094 ARKKAFPPPRPPPPNWEKY-----RLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEE 1148
            A ++  P    P P WE       RL  AA +     +++  +EEEEE+EEEEE+++++E
Sbjct: 231  ASQEVPPELATPAPAWEPQPEPDERLEAAACEVNDLGEEE--EEEEEEDEEEEEDDDDDE 288

Query: 1149 EEEAEEEEEELPPQYFSSETSGSCALNPEEVLEQPQPLSFGHLEGSRQGSQSVPAEQ 1205
             E+  EEE  +P +    E    C   PE++LE+P+  S   LE     S+  PA Q
Sbjct: 289  LEDEGEEEASMPNENSVKEPEIRCDEKPEDLLEEPKTTSEETLEDC---SEVTPAMQ 342


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 55/191 (28%), Positives = 76/191 (39%), Gaps = 44/191 (23%)

Query: 1086 ETQSDLLGARKKAFPPPRPPPPNWE---------------------------KYRLFRAA 1118
            E  SD + A   +  PPRPP   +E                             R   +A
Sbjct: 208  EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSA 267

Query: 1119 QQQKQQQQQQKQQEEEEEEEEEEE----EEEEEEEEEAEEEEEELPPQYFSSETSGSCAL 1174
            +    +     ++EEEEEEEEEEE    EE EEEEEE EEEEEE       +    +  +
Sbjct: 268  ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEV 327

Query: 1175 NPEEVLEQPQPLSFGHL------EGSRQGSQSVPAEQE-------SFALHSSDFLPPIRG 1221
            + EE+ E  +  +  HL         R   +S  AE+E       S AL   D++P    
Sbjct: 328  SEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPA 387

Query: 1222 HLGSQPEQAQP 1232
             L  + +Q  P
Sbjct: 388  LLPIELKQELP 398



 Score = 35.0 bits (79), Expect = 0.54
 Identities = 14/41 (34%), Positives = 26/41 (63%)

Query: 1113 RLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAE 1153
            +L R  +++++ ++QQK+Q E++E E   EE  +E E   E
Sbjct: 158  QLERKRERERKMREQQKEQREQKERERRAEERRKEREARRE 198



 Score = 32.0 bits (71), Expect = 4.6
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 1116 RAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEE--EEELPPQYFSSETSGSCA 1173
            R  + ++QQ++Q++Q+E E   EE  +E E   E  A      E+   +  +S  S S  
Sbjct: 165  RERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPP 224

Query: 1174 LNPEEVLE 1181
              P E  E
Sbjct: 225  RPPRERFE 232


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 55/191 (28%), Positives = 76/191 (39%), Gaps = 44/191 (23%)

Query: 1086 ETQSDLLGARKKAFPPPRPPPPNWE---------------------------KYRLFRAA 1118
            E  SD + A   +  PPRPP   +E                             R   +A
Sbjct: 218  EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSA 277

Query: 1119 QQQKQQQQQQKQQEEEEEEEEEEE----EEEEEEEEEAEEEEEELPPQYFSSETSGSCAL 1174
            +    +     ++EEEEEEEEEEE    EE EEEEEE EEEEEE       +    +  +
Sbjct: 278  ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEV 337

Query: 1175 NPEEVLEQPQPLSFGHL------EGSRQGSQSVPAEQE-------SFALHSSDFLPPIRG 1221
            + EE+ E  +  +  HL         R   +S  AE+E       S AL   D++P    
Sbjct: 338  SEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPA 397

Query: 1222 HLGSQPEQAQP 1232
             L  + +Q  P
Sbjct: 398  LLPIELKQELP 408



 Score = 35.0 bits (79), Expect = 0.54
 Identities = 14/41 (34%), Positives = 26/41 (63%)

Query: 1113 RLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAE 1153
            +L R  +++++ ++QQK+Q E++E E   EE  +E E   E
Sbjct: 168  QLERKRERERKMREQQKEQREQKERERRAEERRKEREARRE 208



 Score = 32.0 bits (71), Expect = 4.6
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 1116 RAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEE--EEELPPQYFSSETSGSCA 1173
            R  + ++QQ++Q++Q+E E   EE  +E E   E  A      E+   +  +S  S S  
Sbjct: 175  RERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPP 234

Query: 1174 LNPEEVLE 1181
              P E  E
Sbjct: 235  RPPRERFE 242


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform 9
            [Homo sapiens]
          Length = 771

 Score = 57.8 bits (138), Expect = 8e-08
 Identities = 52/176 (29%), Positives = 71/176 (40%), Gaps = 44/176 (25%)

Query: 1086 ETQSDLLGARKKAFPPPRPPPPNWE---------------------------KYRLFRAA 1118
            E  SD + A   +  PPRPP   +E                             R   +A
Sbjct: 209  EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSA 268

Query: 1119 QQQKQQQQQQKQQEEEEEEEEEEE----EEEEEEEEEAEEEEEELPPQYFSSETSGSCAL 1174
            +    +     ++EEEEEEEEEEE    EE EEEEEE EEEEEE       +    +  +
Sbjct: 269  ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEV 328

Query: 1175 NPEEVLEQPQPLSFGHL------EGSRQGSQSVPAEQE-------SFALHSSDFLP 1217
            + EE+ E  +  +  HL         R   +S  AE+E       S AL   D++P
Sbjct: 329  SEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVP 384



 Score = 35.0 bits (79), Expect = 0.54
 Identities = 14/41 (34%), Positives = 26/41 (63%)

Query: 1113 RLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAE 1153
            +L R  +++++ ++QQK+Q E++E E   EE  +E E   E
Sbjct: 159  QLERKRERERKMREQQKEQREQKERERRAEERRKEREARRE 199



 Score = 32.0 bits (71), Expect = 4.6
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 1116 RAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEE--EEELPPQYFSSETSGSCA 1173
            R  + ++QQ++Q++Q+E E   EE  +E E   E  A      E+   +  +S  S S  
Sbjct: 166  RERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPP 225

Query: 1174 LNPEEVLE 1181
              P E  E
Sbjct: 226  RPPRERFE 233


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform 8
            [Homo sapiens]
          Length = 780

 Score = 57.8 bits (138), Expect = 8e-08
 Identities = 52/176 (29%), Positives = 71/176 (40%), Gaps = 44/176 (25%)

Query: 1086 ETQSDLLGARKKAFPPPRPPPPNWE---------------------------KYRLFRAA 1118
            E  SD + A   +  PPRPP   +E                             R   +A
Sbjct: 218  EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSA 277

Query: 1119 QQQKQQQQQQKQQEEEEEEEEEEE----EEEEEEEEEAEEEEEELPPQYFSSETSGSCAL 1174
            +    +     ++EEEEEEEEEEE    EE EEEEEE EEEEEE       +    +  +
Sbjct: 278  ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEV 337

Query: 1175 NPEEVLEQPQPLSFGHL------EGSRQGSQSVPAEQE-------SFALHSSDFLP 1217
            + EE+ E  +  +  HL         R   +S  AE+E       S AL   D++P
Sbjct: 338  SEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVP 393



 Score = 35.0 bits (79), Expect = 0.54
 Identities = 14/41 (34%), Positives = 26/41 (63%)

Query: 1113 RLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAE 1153
            +L R  +++++ ++QQK+Q E++E E   EE  +E E   E
Sbjct: 168  QLERKRERERKMREQQKEQREQKERERRAEERRKEREARRE 208



 Score = 32.0 bits (71), Expect = 4.6
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 1116 RAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEE--EEELPPQYFSSETSGSCA 1173
            R  + ++QQ++Q++Q+E E   EE  +E E   E  A      E+   +  +S  S S  
Sbjct: 175  RERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPP 234

Query: 1174 LNPEEVLE 1181
              P E  E
Sbjct: 235  RPPRERFE 242


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform 5
            [Homo sapiens]
          Length = 748

 Score = 57.8 bits (138), Expect = 8e-08
 Identities = 52/176 (29%), Positives = 71/176 (40%), Gaps = 44/176 (25%)

Query: 1086 ETQSDLLGARKKAFPPPRPPPPNWE---------------------------KYRLFRAA 1118
            E  SD + A   +  PPRPP   +E                             R   +A
Sbjct: 186  EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSA 245

Query: 1119 QQQKQQQQQQKQQEEEEEEEEEEE----EEEEEEEEEAEEEEEELPPQYFSSETSGSCAL 1174
            +    +     ++EEEEEEEEEEE    EE EEEEEE EEEEEE       +    +  +
Sbjct: 246  ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEV 305

Query: 1175 NPEEVLEQPQPLSFGHL------EGSRQGSQSVPAEQE-------SFALHSSDFLP 1217
            + EE+ E  +  +  HL         R   +S  AE+E       S AL   D++P
Sbjct: 306  SEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVP 361



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 29/123 (23%), Positives = 49/123 (39%), Gaps = 20/123 (16%)

Query: 1032 KKSEETSVYEEGSSLASMPHPLRSRAFSESHISLAPQSTRAWG-QHRRELFSKGDETQSD 1090
            +K    S   EG   A +    R     + H     ++ R W  Q RRE+  +    + D
Sbjct: 73   EKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERD 132

Query: 1091 LLGARKKAFPPPRPPPPNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEE 1150
             L                    +L R  +++++ ++QQK+Q E++E E   EE  +E E 
Sbjct: 133  RLE-------------------QLERKRERERKMREQQKEQREQKERERRAEERRKEREA 173

Query: 1151 EAE 1153
              E
Sbjct: 174  RRE 176


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform 4
            [Homo sapiens]
          Length = 737

 Score = 57.8 bits (138), Expect = 8e-08
 Identities = 52/176 (29%), Positives = 71/176 (40%), Gaps = 44/176 (25%)

Query: 1086 ETQSDLLGARKKAFPPPRPPPPNWE---------------------------KYRLFRAA 1118
            E  SD + A   +  PPRPP   +E                             R   +A
Sbjct: 175  EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSA 234

Query: 1119 QQQKQQQQQQKQQEEEEEEEEEEE----EEEEEEEEEAEEEEEELPPQYFSSETSGSCAL 1174
            +    +     ++EEEEEEEEEEE    EE EEEEEE EEEEEE       +    +  +
Sbjct: 235  ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEV 294

Query: 1175 NPEEVLEQPQPLSFGHL------EGSRQGSQSVPAEQE-------SFALHSSDFLP 1217
            + EE+ E  +  +  HL         R   +S  AE+E       S AL   D++P
Sbjct: 295  SEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVP 350



 Score = 35.0 bits (79), Expect = 0.54
 Identities = 14/41 (34%), Positives = 26/41 (63%)

Query: 1113 RLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAE 1153
            +L R  +++++ ++QQK+Q E++E E   EE  +E E   E
Sbjct: 125  QLERKRERERKMREQQKEQREQKERERRAEERRKEREARRE 165



 Score = 32.0 bits (71), Expect = 4.6
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 1116 RAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEE--EEELPPQYFSSETSGSCA 1173
            R  + ++QQ++Q++Q+E E   EE  +E E   E  A      E+   +  +S  S S  
Sbjct: 132  RERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPP 191

Query: 1174 LNPEEVLE 1181
              P E  E
Sbjct: 192  RPPRERFE 199


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform 2
            [Homo sapiens]
          Length = 782

 Score = 57.8 bits (138), Expect = 8e-08
 Identities = 52/176 (29%), Positives = 71/176 (40%), Gaps = 44/176 (25%)

Query: 1086 ETQSDLLGARKKAFPPPRPPPPNWE---------------------------KYRLFRAA 1118
            E  SD + A   +  PPRPP   +E                             R   +A
Sbjct: 220  EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSA 279

Query: 1119 QQQKQQQQQQKQQEEEEEEEEEEE----EEEEEEEEEAEEEEEELPPQYFSSETSGSCAL 1174
            +    +     ++EEEEEEEEEEE    EE EEEEEE EEEEEE       +    +  +
Sbjct: 280  ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEV 339

Query: 1175 NPEEVLEQPQPLSFGHL------EGSRQGSQSVPAEQE-------SFALHSSDFLP 1217
            + EE+ E  +  +  HL         R   +S  AE+E       S AL   D++P
Sbjct: 340  SEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVP 395



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 29/123 (23%), Positives = 49/123 (39%), Gaps = 20/123 (16%)

Query: 1032 KKSEETSVYEEGSSLASMPHPLRSRAFSESHISLAPQSTRAWG-QHRRELFSKGDETQSD 1090
            +K    S   EG   A +    R     + H     ++ R W  Q RRE+  +    + D
Sbjct: 107  EKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERD 166

Query: 1091 LLGARKKAFPPPRPPPPNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEE 1150
             L                    +L R  +++++ ++QQK+Q E++E E   EE  +E E 
Sbjct: 167  RLE-------------------QLERKRERERKMREQQKEQREQKERERRAEERRKEREA 207

Query: 1151 EAE 1153
              E
Sbjct: 208  RRE 210


>gi|87298939 hypothetical protein LOC131831 [Homo sapiens]
          Length = 663

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 31/73 (42%), Positives = 46/73 (63%), Gaps = 9/73 (12%)

Query: 1119 QQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALNPEE 1178
            ++ +++ +++ ++EEEEEE EEEEEE EEEEEE EEEEEE+  +    E         E+
Sbjct: 15   KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGE---------EQ 65

Query: 1179 VLEQPQPLSFGHL 1191
             LE P+  S  +L
Sbjct: 66   ELEAPETFSEEYL 78



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 27/58 (46%), Positives = 42/58 (72%), Gaps = 6/58 (10%)

Query: 1116 RAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEE-----EEEEL-PPQYFSSE 1167
            + ++++ ++++++++ EEEEEE EEEEEE EEEEEE  E     EE+EL  P+ FS E
Sbjct: 19   KESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEE 76


>gi|33286444 mastermind-like 2 [Homo sapiens]
          Length = 1156

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 53/234 (22%), Positives = 108/234 (46%), Gaps = 20/234 (8%)

Query: 1107 PNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSS 1166
            P+  K  L    QQQ+QQQQQQ+QQ++++++++++++++++++++      +   Q  S 
Sbjct: 576  PSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQS- 634

Query: 1167 ETSGSCALNPEEVLEQPQPLSFGHLEGSRQGSQSVPAEQESFALHSSDFLP---PIRGHL 1223
                S +   ++  +Q Q       +  +Q  Q  P+ Q + +L S   L    P++  L
Sbjct: 635  ----SISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKL 690

Query: 1224 GSQPEQAQPPCYYGIGGLWRTSGQEATESAKQEFQHFSPPSGAP---GIPTSYSAYYNIS 1280
              Q  Q QP     I G+     Q+  +         + PS +P     P + S Y N  
Sbjct: 691  LLQQMQNQP-----IAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMN-- 743

Query: 1281 VAKAELLN-KLKDQPEMAEIGLGEEEVDHELAQKKIQLIESISRKLSVLREAQR 1333
             ++  LLN +L  + +  +  + E++    L Q+ +   E I+ +  + R   R
Sbjct: 744  -SQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSR 796


>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform 3
            [Homo sapiens]
          Length = 526

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 41/118 (34%), Positives = 57/118 (48%), Gaps = 17/118 (14%)

Query: 1117 AAQQQKQQQQQQKQQEEEEEEEEEEE----EEEEEEEEEAEEEEEELPPQYFSSETSGSC 1172
            +A+    +     ++EEEEEEEEEEE    EE EEEEEE EEEEEE       +    + 
Sbjct: 22   SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 81

Query: 1173 ALNPEEVLEQPQPLSFGHL------EGSRQGSQSVPAEQE-------SFALHSSDFLP 1217
             ++ EE+ E  +  +  HL         R   +S  AE+E       S AL   D++P
Sbjct: 82   EVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVP 139



 Score = 37.7 bits (86), Expect = 0.084
 Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 8/87 (9%)

Query: 1121 QKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALNPEEVL 1180
            Q     ++K    E    E     EEEEEEE EEEEE          TS       EE  
Sbjct: 11   QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE--------GSTSEESEEEEEEEE 62

Query: 1181 EQPQPLSFGHLEGSRQGSQSVPAEQES 1207
            E+ +       E S Q ++ V  E+ S
Sbjct: 63   EEEEETGSNSEEASEQSAEEVSEEEMS 89



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 28/80 (35%), Positives = 34/80 (42%), Gaps = 10/80 (12%)

Query: 1110 EKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEE-------EEELPPQ 1162
            E+  L    Q     +++    E    E     EEEEEEEEE EEE       EEE   +
Sbjct: 2    EERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEE 61

Query: 1163 YFSSETSGSCALNPEEVLEQ 1182
                E +GS   N EE  EQ
Sbjct: 62   EEEEEETGS---NSEEASEQ 78


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,588,177
Number of Sequences: 37866
Number of extensions: 3889332
Number of successful extensions: 98705
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1122
Number of HSP's successfully gapped in prelim test: 616
Number of HSP's that attempted gapping in prelim test: 37651
Number of HSP's gapped (non-prelim): 26081
length of query: 1493
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1378
effective length of database: 13,892,928
effective search space: 19144454784
effective search space used: 19144454784
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.