BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|10835099 organic anion transporting polypeptide A [Homo sapiens] (670 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|10835099 organic anion transporting polypeptide A [Homo sapiens] 1362 0.0 gi|19913403 organic anion transporting polypeptide A [Homo sapiens] 1362 0.0 gi|8394291 solute carrier organic anion transporter family, memb... 615 e-176 gi|225543118 solute carrier organic anion transporter family, me... 603 e-172 gi|225543525 solute carrier organic anion transporter family, me... 542 e-154 gi|225543116 solute carrier organic anion transporter family, me... 540 e-153 gi|9790233 solute carrier organic anion transporter family, memb... 521 e-148 gi|225543114 solute carrier organic anion transporter family, me... 501 e-141 gi|116812593 liver-specific organic anion transporter 3TM12 [Hom... 481 e-135 gi|222831575 solute carrier organic anion transporter family, me... 391 e-108 gi|222831573 solute carrier organic anion transporter family, me... 391 e-108 gi|188528663 solute carrier organic anion transporter family, me... 369 e-102 gi|225637473 solute carrier organic anion transporter family, me... 325 8e-89 gi|223634012 solute carrier organic anion transporter family, me... 325 1e-88 gi|6005820 solute carrier organic anion transporter family, memb... 325 1e-88 gi|38679890 solute carrier organic anion transporter family, mem... 292 6e-79 gi|225637475 solute carrier organic anion transporter family, me... 283 5e-76 gi|39777594 solute carrier organic anion transporter family memb... 281 2e-75 gi|225637477 solute carrier organic anion transporter family, me... 259 4e-69 gi|223634014 solute carrier organic anion transporter family, me... 253 5e-67 gi|93277099 solute carrier organic anion transporter family, mem... 191 1e-48 gi|11863156 RECK protein precursor [Homo sapiens] 37 0.077 gi|5453652 follistatin isoform FST317 precursor [Homo sapiens] 33 1.1 gi|7242222 follistatin isoform FST344 precursor [Homo sapiens] 33 1.1 gi|54873613 agrin [Homo sapiens] 32 1.5 gi|45505132 serine protease inhibitor, Kazal type 1 precursor [H... 32 1.9 gi|12383051 transmembrane protein with EGF-like and two follista... 32 1.9 gi|185134902 olfactory receptor, family 2, subfamily J, member 3... 32 1.9 gi|5031701 follistatin-like 3 glycoprotein precursor [Homo sapiens] 32 2.5 gi|74275344 trace amine associated receptor 2 isoform 1 [Homo sa... 31 3.2 >gi|10835099 organic anion transporting polypeptide A [Homo sapiens] Length = 670 Score = 1362 bits (3526), Expect = 0.0 Identities = 670/670 (100%), Positives = 670/670 (100%) Query: 1 MGETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGF 60 MGETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGF Sbjct: 1 MGETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGF 60 Query: 61 INGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVS 120 INGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVS Sbjct: 61 INGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVS 120 Query: 121 VSGNLSSNSFLCMENGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGI 180 VSGNLSSNSFLCMENGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGI Sbjct: 121 VSGNLSSNSFLCMENGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGI 180 Query: 181 SYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTR 240 SYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTR Sbjct: 181 SYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTR 240 Query: 241 WVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYG 300 WVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYG Sbjct: 241 WVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYG 300 Query: 301 ITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGI 360 ITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGI Sbjct: 301 ITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGI 360 Query: 361 YNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINT 420 YNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINT Sbjct: 361 YNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINT 420 Query: 421 SYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMV 480 SYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMV Sbjct: 421 SYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMV 480 Query: 481 FQNCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMK 540 FQNCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMK Sbjct: 481 FQNCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMK 540 Query: 541 SEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYI 600 SEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYI Sbjct: 541 SEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYI 600 Query: 601 YLGLPAALRGSSFVPALIILILLRKCHLPGENASSGTELIETKVKGKENECKDIYQKSTV 660 YLGLPAALRGSSFVPALIILILLRKCHLPGENASSGTELIETKVKGKENECKDIYQKSTV Sbjct: 601 YLGLPAALRGSSFVPALIILILLRKCHLPGENASSGTELIETKVKGKENECKDIYQKSTV 660 Query: 661 LKDDELKTKL 670 LKDDELKTKL Sbjct: 661 LKDDELKTKL 670 >gi|19913403 organic anion transporting polypeptide A [Homo sapiens] Length = 670 Score = 1362 bits (3526), Expect = 0.0 Identities = 670/670 (100%), Positives = 670/670 (100%) Query: 1 MGETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGF 60 MGETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGF Sbjct: 1 MGETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGF 60 Query: 61 INGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVS 120 INGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVS Sbjct: 61 INGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVS 120 Query: 121 VSGNLSSNSFLCMENGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGI 180 VSGNLSSNSFLCMENGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGI Sbjct: 121 VSGNLSSNSFLCMENGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGI 180 Query: 181 SYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTR 240 SYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTR Sbjct: 181 SYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTR 240 Query: 241 WVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYG 300 WVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYG Sbjct: 241 WVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYG 300 Query: 301 ITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGI 360 ITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGI Sbjct: 301 ITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGI 360 Query: 361 YNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINT 420 YNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINT Sbjct: 361 YNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINT 420 Query: 421 SYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMV 480 SYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMV Sbjct: 421 SYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMV 480 Query: 481 FQNCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMK 540 FQNCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMK Sbjct: 481 FQNCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMK 540 Query: 541 SEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYI 600 SEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYI Sbjct: 541 SEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYI 600 Query: 601 YLGLPAALRGSSFVPALIILILLRKCHLPGENASSGTELIETKVKGKENECKDIYQKSTV 660 YLGLPAALRGSSFVPALIILILLRKCHLPGENASSGTELIETKVKGKENECKDIYQKSTV Sbjct: 601 YLGLPAALRGSSFVPALIILILLRKCHLPGENASSGTELIETKVKGKENECKDIYQKSTV 660 Query: 661 LKDDELKTKL 670 LKDDELKTKL Sbjct: 661 LKDDELKTKL 670 >gi|8394291 solute carrier organic anion transporter family, member 1C1 isoform 2 [Homo sapiens] Length = 712 Score = 615 bits (1586), Expect = e-176 Identities = 295/641 (46%), Positives = 426/641 (66%), Gaps = 18/641 (2%) Query: 3 ETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFIN 62 +TE + C +LK+FL A++ + +K L+ Y+ S +TQIER+F+IP+SLVG I+ Sbjct: 26 KTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVID 85 Query: 63 GSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVS 122 GSFEIGNLL+I FVSYFG KLHRP +IG GCV+MG+G L ++P F M QY+YE S Sbjct: 86 GSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS 145 Query: 123 GNLSSNSFLCMENGTQILRPTQDPS------ECTKEVKSLMWVYVLVGNIVRGMGETPIL 176 + S S +E+ +Q+ + S EC + S MW+YV +GN++RG+GETPI Sbjct: 146 NSTLSISPCLLESSSQLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQ 205 Query: 177 PLGISYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITP 236 PLGI+Y++DFA +N+ YIG V+T AIIGP+ G LL S CA +YVD GFVN D + ITP Sbjct: 206 PLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITP 265 Query: 237 TDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNAD-------IIKNENEDK 289 D +WVGAWW G+LI +++L A+PF++LP +LP+ +++ I +++ D Sbjct: 266 KDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDY 325 Query: 290 QKEEVKKEKY-GITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYG 348 Q + + K + +DFLP +K+L NP+Y L++ S +QFN+ M+++ PKY+EQQYG Sbjct: 326 QTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYG 385 Query: 349 ISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLM 408 SSS A F++G+ N+P + +G GG++MKKF+I+V AA + S+ YLL+ F + Sbjct: 386 QSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFAL 445 Query: 409 TCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAG 468 CENS V G+ SY+G Y E +F+DCN C C W+P+CG NG++Y+SACLAG Sbjct: 446 GCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAG 505 Query: 469 CETSIGTGINMVFQNCSCI----QTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIY 524 C+TS +G N++F NC+C+ SGNSS ++G C K C M YFL++S ++S+ Sbjct: 506 CQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTL 565 Query: 525 SLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCG 584 SL IPGY++LLRC+K + KS +G++T RV AGIPAP+YFG L+D++CL WG +CG Sbjct: 566 SLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCG 625 Query: 585 ESGACRIYDSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625 G+CR+YDS FR+IYLGL L S + ++ +L +L+K Sbjct: 626 SRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKK 666 >gi|225543118 solute carrier organic anion transporter family, member 1C1 isoform 1 [Homo sapiens] Length = 730 Score = 603 bits (1554), Expect = e-172 Identities = 288/623 (46%), Positives = 414/623 (66%), Gaps = 18/623 (2%) Query: 3 ETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFIN 62 +TE + C +LK+FL A++ + +K L+ Y+ S +TQIER+F+IP+SLVG I+ Sbjct: 26 KTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVID 85 Query: 63 GSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVS 122 GSFEIGNLL+I FVSYFG KLHRP +IG GCV+MG+G L ++P F M QY+YE S Sbjct: 86 GSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS 145 Query: 123 GNLSSNSFLCMENGTQILRPTQDPS------ECTKEVKSLMWVYVLVGNIVRGMGETPIL 176 + S S +E+ +Q+ + S EC + S MW+YV +GN++RG+GETPI Sbjct: 146 NSTLSISPCLLESSSQLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQ 205 Query: 177 PLGISYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITP 236 PLGI+Y++DFA +N+ YIG V+T AIIGP+ G LL S CA +YVD GFVN D + ITP Sbjct: 206 PLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITP 265 Query: 237 TDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNAD-------IIKNENEDK 289 D +WVGAWW G+LI +++L A+PF++LP +LP+ +++ I +++ D Sbjct: 266 KDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDY 325 Query: 290 QKEEVKKEKY-GITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYG 348 Q + + K + +DFLP +K+L NP+Y L++ S +QFN+ M+++ PKY+EQQYG Sbjct: 326 QTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYG 385 Query: 349 ISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLM 408 SSS A F++G+ N+P + +G GG++MKKF+I+V AA + S+ YLL+ F + Sbjct: 386 QSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFAL 445 Query: 409 TCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAG 468 CENS V G+ SY+G Y E +F+DCN C C W+P+CG NG++Y+SACLAG Sbjct: 446 GCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAG 505 Query: 469 CETSIGTGINMVFQNCSCI----QTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIY 524 C+TS +G N++F NC+C+ SGNSS ++G C K C M YFL++S ++S+ Sbjct: 506 CQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTL 565 Query: 525 SLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCG 584 SL IPGY++LLRC+K + KS +G++T RV AGIPAP+YFG L+D++CL WG +CG Sbjct: 566 SLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCG 625 Query: 585 ESGACRIYDSTTFRYIYLGLPAA 607 G+CR+YDS FRY +PA+ Sbjct: 626 SRGSCRLYDSNVFRYQIKSIPAS 648 >gi|225543525 solute carrier organic anion transporter family, member 1B1 [Homo sapiens] Length = 691 Score = 542 bits (1397), Expect = e-154 Identities = 272/635 (42%), Positives = 401/635 (63%), Gaps = 20/635 (3%) Query: 9 ETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIG 68 E + R + LKMFL A++ +F++KTL M S + IER+F I +SLVGFI+GSFEIG Sbjct: 17 ENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFEIG 76 Query: 69 NLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEY--ESTVSVSGNLS 126 NLL+I+FVSYFG+KLHRP +IGIGC +MG+G L +LPHF M Y Y E+ ++ S N + Sbjct: 77 NLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSSENST 136 Query: 127 SNSFLCMENGTQILRPTQDPSE-----CTKEVKSLMWVYVLVGNIVRGMGETPILPLGIS 181 S C+ N QIL + E C KE S MW+YV +GN++RG+GETPI+PLG+S Sbjct: 137 STLSTCLIN--QILSLNRASPEIVGKGCLKESGSYMWIYVFMGNMLRGIGETPIVPLGLS 194 Query: 182 YIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRW 241 YI+DFAK +S LY+G++ A+IGP+IG L S + +YVD G+V+ + ITPTD+RW Sbjct: 195 YIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRW 254 Query: 242 VGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNAD----IIKNENEDKQKEEVKKE 297 VGAWW FL+ +++++IPFFFLP T K E A +++ +E Q + + Sbjct: 255 VGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLETNDEKDQTANLTNQ 314 Query: 298 KYGITKD---FLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDA 354 ITK+ F KS+ NP+Y++F+L++++Q ++++ +++ KY+EQQYG SS A Sbjct: 315 GKNITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKA 374 Query: 355 IFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSS 414 L+G+ +P G +GG I+KKFK+ A C+ +++ Y L F + CEN S Sbjct: 375 NILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKS 434 Query: 415 VVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIG 474 V G+ +Y+G + + CN DCNC W+PVCGNNG++Y+S CLAGC++S G Sbjct: 435 VAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSG 494 Query: 475 TGINMVFQNCSCIQTSG----NSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIP 530 +VF NCSC++ +G N SA LG C + C+ +F+ + ++ F +L Sbjct: 495 NKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGTS 554 Query: 531 GYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACR 590 M++++ ++ E KSL +G H+ R GI APIYFGAL+D+TC+ W T CG G+CR Sbjct: 555 HVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSCR 614 Query: 591 IYDSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625 Y+ST+F +YLGL + LR SS V +I++ ++K Sbjct: 615 TYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKK 649 >gi|225543116 solute carrier organic anion transporter family, member 1C1 isoform 3 [Homo sapiens] Length = 663 Score = 540 bits (1390), Expect = e-153 Identities = 274/635 (43%), Positives = 394/635 (62%), Gaps = 55/635 (8%) Query: 3 ETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFIN 62 +TE + C +LK+FL A++ + +K L+ Y+ S +TQIER+F+IP+SLVG I+ Sbjct: 26 KTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVID 85 Query: 63 GSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVS 122 GSFEIGNLL+I FVSYFG KLHRP +IG GCV+MG+G L ++P F M QY+YE Sbjct: 86 GSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERY---- 141 Query: 123 GNLSSNSFLCMENGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISY 182 + SSNS L + S C E S + V V+ Sbjct: 142 -SPSSNSTLSI-------------SPCLLESSSQLPVSVM-------------------- 167 Query: 183 IEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWV 242 + S + G V+T AIIGP+ G LL S CA +YVD GFVN D + ITP D +WV Sbjct: 168 -----EKSKSKISNGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWV 222 Query: 243 GAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNAD-------IIKNENEDKQKEEVK 295 GAWW G+LI +++L A+PF++LP +LP+ +++ I +++ D Q + + Sbjct: 223 GAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGE 282 Query: 296 KEKY-GITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDA 354 K + +DFLP +K+L NP+Y L++ S +QFN+ M+++ PKY+EQQYG SSS A Sbjct: 283 NAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRA 342 Query: 355 IFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSS 414 F++G+ N+P + +G GG++MKKF+I+V AA + S+ YLL+ F + CENS Sbjct: 343 NFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSD 402 Query: 415 VVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIG 474 V G+ SY+G Y E +F+DCN C C W+P+CG NG++Y+SACLAGC+TS Sbjct: 403 VAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNR 462 Query: 475 TGINMVFQNCSCI----QTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIP 530 +G N++F NC+C+ SGNSS ++G C K C M YFL++S ++S+ SL IP Sbjct: 463 SGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIP 522 Query: 531 GYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACR 590 GY++LLRC+K + KS +G++T RV AGIPAP+YFG L+D++CL WG +CG G+CR Sbjct: 523 GYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCR 582 Query: 591 IYDSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625 +YDS FR+IYLGL L S + ++ +L +L+K Sbjct: 583 LYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKK 617 >gi|9790233 solute carrier organic anion transporter family, member 1B3 [Homo sapiens] Length = 702 Score = 521 bits (1342), Expect = e-148 Identities = 261/633 (41%), Positives = 393/633 (62%), Gaps = 16/633 (2%) Query: 9 ETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIG 68 E + R + KMFL A++ ++++K L G M +TQIER+F+I +SL G I+GSFEIG Sbjct: 17 EKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGLIDGSFEIG 76 Query: 69 NLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEY--ESTVSVSGNLS 126 NLL+I+FVSYFG+KLHRP +IGIGC++MG G L SLPHF M Y Y E+ ++ S N + Sbjct: 77 NLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGYYRYSKETHINPSENST 136 Query: 127 SNSFLCMENGTQILRPTQDP---SECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYI 183 S+ C+ N T T +C KE S MW+YV +GN++RG+GETPI+PLGISYI Sbjct: 137 SSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWIYVFMGNMLRGIGETPIVPLGISYI 196 Query: 184 EDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVG 243 +DFAK +S LY+G + +IGP+IG L S A +YVD G+V+ + ITP D+RWVG Sbjct: 197 DDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLSTIRITPKDSRWVG 256 Query: 244 AWWFGFLICAGVNVLTAIPFFFLPNTLPK----EGLETNADIIKNENEDKQKEEVKKEKY 299 AWW GFL+ +++++IPFFFLP K + + ++K ++ Q + + Sbjct: 257 AWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLKTNDDRNQTANLTNQGK 316 Query: 300 GITKD---FLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIF 356 +TK+ F +KS+ NP+Y++F+L++++Q ++F+ +++ KY+EQQYG S+S A F Sbjct: 317 NVTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANF 376 Query: 357 LMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVV 416 L+GI +P + G +GG I+KKFK+++ A S++ +L L F + CE+ SV Sbjct: 377 LLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVA 436 Query: 417 GINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTG 476 G+ +Y+G + + CN +CNC W+PVCGNNG++YLS CLAGC++S G Sbjct: 437 GLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGIK 496 Query: 477 INMVFQNCSCIQTSG----NSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGY 532 + VF NCSC++ +G N SA LG C + C+ ++ + ++S + Sbjct: 497 KHTVFYNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSLFSATGGTTFI 556 Query: 533 MVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIY 592 ++ ++ ++ E K+L +G + R GI APIYFGAL+D TC+ W T CG GACRIY Sbjct: 557 LLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNSCGAQGACRIY 616 Query: 593 DSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625 +S F +YLGL ALR + V ++ + ++K Sbjct: 617 NSVFFGRVYLGLSIALRFPALVLYIVFIFAMKK 649 >gi|225543114 solute carrier organic anion transporter family, member 1C1 isoform 4 [Homo sapiens] Length = 612 Score = 501 bits (1289), Expect = e-141 Identities = 237/530 (44%), Positives = 345/530 (65%), Gaps = 18/530 (3%) Query: 96 MGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCMENGTQILRPTQDPS------EC 149 MG+G L ++P F M QY+YE S + S S +E+ +Q+ + S EC Sbjct: 1 MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC 60 Query: 150 TKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIGLVETGAIIGPLI 209 + S MW+YV +GN++RG+GETPI PLGI+Y++DFA +N+ YIG V+T AIIGP+ Sbjct: 61 EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF 120 Query: 210 GLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNT 269 G LL S CA +YVD GFVN D + ITP D +WVGAWW G+LI +++L A+PF++LP + Sbjct: 121 GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS 180 Query: 270 LPKEGLETNAD-------IIKNENEDKQKEEVKKEKY-GITKDFLPFMKSLSCNPIYMLF 321 LP+ +++ I +++ D Q + + K + +DFLP +K+L NP+Y L+ Sbjct: 181 LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY 240 Query: 322 ILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFK 381 + S +QFN+ M+++ PKY+EQQYG SSS A F++G+ N+P + +G GG++MKKF+ Sbjct: 241 LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR 300 Query: 382 ITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEGIPQDLYVENDIFADCNV 441 I+V AA + S+ YLL+ F + CENS V G+ SY+G Y E +F+DCN Sbjct: 301 ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS 360 Query: 442 DCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMVFQNCSCI----QTSGNSSAVL 497 C C W+P+CG NG++Y+SACLAGC+TS +G N++F NC+C+ SGNSS ++ Sbjct: 361 RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV 420 Query: 498 GLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRV 557 G C K C M YFL++S ++S+ SL IPGY++LLRC+K + KS +G++T RV Sbjct: 421 GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV 480 Query: 558 FAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAA 607 AGIPAP+YFG L+D++CL WG +CG G+CR+YDS FRY +PA+ Sbjct: 481 LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRYQIKSIPAS 530 >gi|116812593 liver-specific organic anion transporter 3TM12 [Homo sapiens] Length = 640 Score = 481 bits (1237), Expect = e-135 Identities = 250/605 (41%), Positives = 371/605 (61%), Gaps = 22/605 (3%) Query: 40 MNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLG 99 M TQIER+F I +SLVG I+GSFEIGNL +I+FVSYFG+KLHRP +IGIGC +MG G Sbjct: 1 MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60 Query: 100 CFLKSLPHFLMNQYEY--ESTVSVSGNLSSNSFLCMENGTQILRPTQDPSE-----CTKE 152 L +LPHF M Y Y E+ + S N +SN C+ N Q+L + PSE C KE Sbjct: 61 SILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLIN--QMLSLNRTPSEIIERGCVKE 118 Query: 153 VKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIGLVETGAIIGPLIGLL 212 S MW+YV +GN++RG+GETPI+PLGISYI+DFAK +S LY+G V + G + + Sbjct: 119 SGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFM 178 Query: 213 LASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNTLPK 272 L S A +YVD G+V+ + ITP D+RWVGAWW GFL+ V+++++IPFFFLP K Sbjct: 179 LGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNK 238 Query: 273 EGLETNAD----IIKNENEDKQKEEVKKEKYGITKD---FLPFMKSLSCNPIYMLFILVS 325 E ++K ++ Q + + ITK+ F +KS+ NP+Y++F++ + Sbjct: 239 PQKERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVIFT 298 Query: 326 VIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVK 385 ++ ++++ ++++ K +EQQYG S+S FL+G+ LP + IG GG I+KKFK+++ Sbjct: 299 LLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLV 358 Query: 386 QAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEG-IPQDLYVENDIFADCNVDCN 444 A + + + L L F + CE+ SV G+ +Y+G P +V+ + + CN +CN Sbjct: 359 GLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPL-SYCNSECN 417 Query: 445 CPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMVFQNCSCIQTSG----NSSAVLGLC 500 C W+PVCGNNG++YLS CLAGC++S G +VF NCSC++ G N SA LG C Sbjct: 418 CDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSAHLGEC 477 Query: 501 DKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAG 560 + C+ + ++ + +F+ ++ ++++R ++ E K+L +G H+ R G Sbjct: 478 PRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGG 537 Query: 561 IPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRGSSFVPALIIL 620 I PIYFGAL+D+TC+ W T CG GACRIY+ST + GL AL V + + Sbjct: 538 ILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTVFI 597 Query: 621 ILLRK 625 ++RK Sbjct: 598 FVVRK 602 >gi|222831575 solute carrier organic anion transporter family, member 3A1 isoform 1 [Homo sapiens] Length = 710 Score = 391 bits (1004), Expect = e-108 Identities = 213/620 (34%), Positives = 343/620 (55%), Gaps = 29/620 (4%) Query: 12 RIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLL 71 ++ C S +K+FL++ +++ G+Y+ S+LT +ER+FN+ ++ VG I SFEIGNL Sbjct: 32 KVSCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNLA 91 Query: 72 LIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFL 131 LI+FVSYFG + HRP +IG G +VM LG L +LP FL +QY+YE+ G + + Sbjct: 92 LILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWG--AEGRDV 149 Query: 132 CMENGTQILRPTQDPSECTKEVKSLMWVYVLVG-NIVRGMGETPILPLGISYIEDFAKFE 190 C NG+ C + M +L+G ++ G+G TP+ PLG+SYI+D + + Sbjct: 150 CAANGSGGDEGPDPDLICRNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRK 209 Query: 191 NSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFL 250 +S LYIG++ T + GP G +L SFC +YVD F++T +L ITP D RW+GAWW GFL Sbjct: 210 DSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFL 269 Query: 251 ICAGVNVLTAIPFFFLPNTLP---KEGLETNADIIKNENEDKQKEEVKKEKYGITKD--- 304 +C + +++ F P +LP + +E+ ++ ++ K ++ + D Sbjct: 270 LCGALLFFSSLLMFGFPQSLPPHSEPAMESEQAMLSEREYERPKPSNGVLRHPLEPDSSA 329 Query: 305 -------FLP-FMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIF 356 +P K L NP++ IL + ++ +F+ KYLEQQ+ +++S A Sbjct: 330 SCFQQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQ 389 Query: 357 LMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVV 416 L+G+ +P C+G +GGL++KK ++ A + ++L+ Y + C+ V Sbjct: 390 LLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVA 449 Query: 417 GINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTG 476 G+ Y G D ++ CN +C C + + PVCG +G++YLSAC AGC ++ TG Sbjct: 450 GVTVPY-GNSTAPGSALDPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNSTNLTG 508 Query: 477 INMVFQNCSCIQT--SGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMV 534 C+C+ T + N++ V G C P C FL + + S I ++A P ++ Sbjct: 509 -------CACLTTVPAENATVVPGKC-PSPGCQEAFLTFLCVMCICSLIGAMAQTPSVII 560 Query: 535 LLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDS 594 L+R + E KS +G+ R+ IP P+ FGA +DSTCL W T CGE GAC +YD+ Sbjct: 561 LIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTF-CGEQGACVLYDN 619 Query: 595 TTFRYIYLGLPAALRGSSFV 614 +RY+Y+ + AL+ +F+ Sbjct: 620 VVYRYLYVSIAIALKSFAFI 639 >gi|222831573 solute carrier organic anion transporter family, member 3A1 isoform 2 [Homo sapiens] Length = 692 Score = 391 bits (1004), Expect = e-108 Identities = 213/620 (34%), Positives = 343/620 (55%), Gaps = 29/620 (4%) Query: 12 RIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLL 71 ++ C S +K+FL++ +++ G+Y+ S+LT +ER+FN+ ++ VG I SFEIGNL Sbjct: 32 KVSCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNLA 91 Query: 72 LIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFL 131 LI+FVSYFG + HRP +IG G +VM LG L +LP FL +QY+YE+ G + + Sbjct: 92 LILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWG--AEGRDV 149 Query: 132 CMENGTQILRPTQDPSECTKEVKSLMWVYVLVG-NIVRGMGETPILPLGISYIEDFAKFE 190 C NG+ C + M +L+G ++ G+G TP+ PLG+SYI+D + + Sbjct: 150 CAANGSGGDEGPDPDLICRNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRK 209 Query: 191 NSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFL 250 +S LYIG++ T + GP G +L SFC +YVD F++T +L ITP D RW+GAWW GFL Sbjct: 210 DSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFL 269 Query: 251 ICAGVNVLTAIPFFFLPNTLP---KEGLETNADIIKNENEDKQKEEVKKEKYGITKD--- 304 +C + +++ F P +LP + +E+ ++ ++ K ++ + D Sbjct: 270 LCGALLFFSSLLMFGFPQSLPPHSEPAMESEQAMLSEREYERPKPSNGVLRHPLEPDSSA 329 Query: 305 -------FLP-FMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIF 356 +P K L NP++ IL + ++ +F+ KYLEQQ+ +++S A Sbjct: 330 SCFQQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQ 389 Query: 357 LMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVV 416 L+G+ +P C+G +GGL++KK ++ A + ++L+ Y + C+ V Sbjct: 390 LLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVA 449 Query: 417 GINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTG 476 G+ Y G D ++ CN +C C + + PVCG +G++YLSAC AGC ++ TG Sbjct: 450 GVTVPY-GNSTAPGSALDPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNSTNLTG 508 Query: 477 INMVFQNCSCIQT--SGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMV 534 C+C+ T + N++ V G C P C FL + + S I ++A P ++ Sbjct: 509 -------CACLTTVPAENATVVPGKC-PSPGCQEAFLTFLCVMCICSLIGAMAQTPSVII 560 Query: 535 LLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDS 594 L+R + E KS +G+ R+ IP P+ FGA +DSTCL W T CGE GAC +YD+ Sbjct: 561 LIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTF-CGEQGACVLYDN 619 Query: 595 TTFRYIYLGLPAALRGSSFV 614 +RY+Y+ + AL+ +F+ Sbjct: 620 VVYRYLYVSIAIALKSFAFI 639 >gi|188528663 solute carrier organic anion transporter family, member 2A1 [Homo sapiens] Length = 643 Score = 369 bits (947), Expect = e-102 Identities = 215/602 (35%), Positives = 324/602 (53%), Gaps = 39/602 (6%) Query: 19 LKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSY 78 +K+F+L + + L +Y S LT IE++F + +S G I+ EI N +LIIFVSY Sbjct: 31 IKVFVLCQGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNAILIIFVSY 90 Query: 79 FGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCMENGTQ 138 FG+++HRP +IGIG + + G F+ +LPHFL Y+Y T++ +GN S + Q Sbjct: 91 FGSRVHRPRLIGIGGLFLAAGAFILTLPHFLSEPYQY--TLASTGNNSRLQAELCQKHWQ 148 Query: 139 ILRP------TQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENS 192 L P TQ+P + T S MW ++V ++ G+G PI P GISY++DF++ NS Sbjct: 149 DLPPSKCHSTTQNPQKET----SSMWGLMVVAQLLAGIGTVPIQPFGISYVDDFSEPSNS 204 Query: 193 PLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLIC 252 PLYI ++ ++ GP G LL S ++VD G VNT + + P D RW+GAWW G LI Sbjct: 205 PLYISILFAISVFGPAFGYLLGSVMLQIFVDYGRVNTAAVNLVPGDPRWIGAWWLGLLIS 264 Query: 253 AGVNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYGITKDFLP----F 308 + + VLT+ PFFF P +P A +E ++ EE K G DF+ Sbjct: 265 SALLVLTSFPFFFFPRAMPIGAKRAPA----TADEARKLEEAKSR--GSLVDFIKRFPCI 318 Query: 309 MKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICI 368 L N +++L +L + + +F+ K+LE+QYG S++ A FL+G NLP + Sbjct: 319 FLRLLMNSLFVLVVLAQCTFSSVIAGLSTFLNKFLEKQYGTSAAYANFLIGAVNLPAAAL 378 Query: 369 GYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGI---NTSYEGI 425 G + GG++MK+F +++ I + + +L F M C +V + +TS Sbjct: 379 GMLFGGILMKRFVFSLQAIPRIATTIITISMILCVPLFFMGCSTPTVAEVYPPSTSSSIH 438 Query: 426 PQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCET---SIGTGINMVFQ 482 PQ C DC+CP I+ PVCG+NG+ YLS C AGC S T +++ Sbjct: 439 PQS--------PACRRDCSCPDSIFHPVCGDNGIEYLSPCHAGCSNINMSSATSKQLIYL 490 Query: 483 NCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSE 542 NCSC+ T G++SA G C C+ L + L + S I ++ P YM++LR + E Sbjct: 491 NCSCV-TGGSASAKTGSCP--VPCAHFLLPAIFLISFVSLIACISHNPLYMMVLRVVNQE 547 Query: 543 EKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYL 602 EKS +G+ R+ A +P+P +G +D +C+ W +L G GAC YD+ R YL Sbjct: 548 EKSFAIGVQFLLMRLLAWLPSPALYGLTIDHSCIRWNSLCLGRRGACAYYDNDALRDRYL 607 Query: 603 GL 604 GL Sbjct: 608 GL 609 >gi|225637473 solute carrier organic anion transporter family, member 5A1 isoform 1 [Homo sapiens] Length = 848 Score = 325 bits (833), Expect = 8e-89 Identities = 200/645 (31%), Positives = 335/645 (51%), Gaps = 63/645 (9%) Query: 16 LSKLKMFLLAIT-CAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLII 74 L+ + FL+ + F+ + Y++S++T IER++++ +S G + F+IGNL++++ Sbjct: 124 LTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVV 183 Query: 75 FVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSS-NSFLCM 133 FVSYFG + RP+ + +G +++ G L +LPHF+ Y+ + N S+ N LC Sbjct: 184 FVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQEL-----NASAPNDGLCQ 238 Query: 134 ENGTQILRPTQDPSECTKEVK-SLMWVYV---LVGNIVRGMGETPILPLGISYIEDFAKF 189 + T +P C K+ + WVYV + I+ GMG TPI LG +Y++D K Sbjct: 239 GGNSTA---TLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKK 295 Query: 190 ENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGF 249 ENS LY+ ++ +GP +G LL YVD + + + D R++G WW GF Sbjct: 296 ENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVDP----RNPVHLDQNDPRFIGNWWSGF 351 Query: 250 LICAGVNVLTAIPFFFLPNTLP-------KEGLETNA----DIIKNENEDKQKEEVKKEK 298 L+CA L P F P LP K+ +A D++K ++ + ++ + K Sbjct: 352 LLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSS 411 Query: 299 YGITKDF--LPFMKSLSCNPIYMLFILVSVIQFNAFVN-MISFMPKYLEQQYGISSSDAI 355 G KD LP + + LF+ +S +A V I+F+PK++E Q+GI +S+A Sbjct: 412 MGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNAS 471 Query: 356 FLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSV 415 G+ +P +G ++GG I+KK K+ +++A + S + L + F++ CE+ ++ Sbjct: 472 IYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINL 531 Query: 416 VGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETS--I 473 GIN Y P ++ CNV+C C ++PVCG++G++Y + CLAGC S + Sbjct: 532 GGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNL 591 Query: 474 GTGINMVFQNCSCIQT------------------------SGNSSAVLGLCDKGPDCSLM 509 TGI + C+C+Q+ + N AV G C + C+ + Sbjct: 592 STGIRN-YTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKR--TCNTL 648 Query: 510 LQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGA 569 + FL+ + +FI + A +V LR ++ EE+ +G+ R A IP PIYFGA Sbjct: 649 IP-FLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGA 707 Query: 570 LMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRGSSFV 614 ++D+TC+ W +CG G+C Y+ T+FR++Y GL A L+ F+ Sbjct: 708 VIDTTCMLW-QQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFI 751 >gi|223634012 solute carrier organic anion transporter family, member 2B1 isoform 2 [Homo sapiens] Length = 687 Score = 325 bits (832), Expect = 1e-88 Identities = 197/642 (30%), Positives = 333/642 (51%), Gaps = 49/642 (7%) Query: 19 LKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSY 78 +K+F+L + +++ + Y+ S ++ +E++F + + G + E+GN LI+FVSY Sbjct: 26 IKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSY 85 Query: 79 FGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCMENGTQ 138 FG+++HRP MIG G +++ L L +LPHF+ Y Y++T + LC+ + Sbjct: 86 FGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSA 145 Query: 139 ILRPTQDPSE--CTK--EVKSLMWVYVL-VGNIVRGMGETPILPLGISYIEDFAKFENSP 193 P PS C+ E + L V ++ V + G+G PI P GISYI+DFA NSP Sbjct: 146 ---PASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSP 202 Query: 194 LYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICA 253 LY+G++ ++GP + L S +YVD + + +T D RWVGAWW GFLI A Sbjct: 203 LYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAA 262 Query: 254 GVNVLTAIPFFFLPNTLPKEGLE----------TNADIIKNENEDKQKE--EVKKEKYGI 301 G L AIP+FF P +PKE E T++ K ++ ++ E K++ G+ Sbjct: 263 GAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGL 322 Query: 302 T------------KDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGI 349 K F + +PI++L +L V + M +F+PK+LE+Q+ I Sbjct: 323 VQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSI 382 Query: 350 SSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLS-FLM 408 ++S A L+G + P + +G ++GG+++K+ + + C L +L L + L F + Sbjct: 383 TASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGAL-CLLGMLLCLFFSLPLFFI 441 Query: 409 TCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCG-NNGLSYLSACLA 467 C + + GI P ++ C C+CP ++PVC + + Y++ C A Sbjct: 442 GCSSHQIAGITHQTSAHP-----GLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHA 496 Query: 468 GCETSIG----TGINMVFQNCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFI 523 GC + + + + NCSC+ GN + G CD CS ++ FL+L ++ S + Sbjct: 497 GCSSWVVQDALDNSQVFYTNCSCV-VEGN-PVLAGSCDS--TCSHLVVPFLLLVSLGSAL 552 Query: 524 YSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKC 583 L P +M++LR +K E+K+L VG+ R+ A +P+P+ G+ +D+TC+HW L C Sbjct: 553 ACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHW-ALSC 611 Query: 584 GESGACRIYDSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625 G CR Y++ R ++GL + S + ++L +LR+ Sbjct: 612 GRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQ 653 >gi|6005820 solute carrier organic anion transporter family, member 2B1 isoform 1 [Homo sapiens] Length = 709 Score = 325 bits (832), Expect = 1e-88 Identities = 197/642 (30%), Positives = 333/642 (51%), Gaps = 49/642 (7%) Query: 19 LKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSY 78 +K+F+L + +++ + Y+ S ++ +E++F + + G + E+GN LI+FVSY Sbjct: 48 IKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSY 107 Query: 79 FGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCMENGTQ 138 FG+++HRP MIG G +++ L L +LPHF+ Y Y++T + LC+ + Sbjct: 108 FGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSA 167 Query: 139 ILRPTQDPSE--CTK--EVKSLMWVYVL-VGNIVRGMGETPILPLGISYIEDFAKFENSP 193 P PS C+ E + L V ++ V + G+G PI P GISYI+DFA NSP Sbjct: 168 ---PASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSP 224 Query: 194 LYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICA 253 LY+G++ ++GP + L S +YVD + + +T D RWVGAWW GFLI A Sbjct: 225 LYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAA 284 Query: 254 GVNVLTAIPFFFLPNTLPKEGLE----------TNADIIKNENEDKQKE--EVKKEKYGI 301 G L AIP+FF P +PKE E T++ K ++ ++ E K++ G+ Sbjct: 285 GAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGL 344 Query: 302 T------------KDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGI 349 K F + +PI++L +L V + M +F+PK+LE+Q+ I Sbjct: 345 VQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSI 404 Query: 350 SSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLS-FLM 408 ++S A L+G + P + +G ++GG+++K+ + + C L +L L + L F + Sbjct: 405 TASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGAL-CLLGMLLCLFFSLPLFFI 463 Query: 409 TCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCG-NNGLSYLSACLA 467 C + + GI P ++ C C+CP ++PVC + + Y++ C A Sbjct: 464 GCSSHQIAGITHQTSAHP-----GLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHA 518 Query: 468 GCETSIG----TGINMVFQNCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFI 523 GC + + + + NCSC+ GN + G CD CS ++ FL+L ++ S + Sbjct: 519 GCSSWVVQDALDNSQVFYTNCSCV-VEGN-PVLAGSCDS--TCSHLVVPFLLLVSLGSAL 574 Query: 524 YSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKC 583 L P +M++LR +K E+K+L VG+ R+ A +P+P+ G+ +D+TC+HW L C Sbjct: 575 ACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHW-ALSC 633 Query: 584 GESGACRIYDSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625 G CR Y++ R ++GL + S + ++L +LR+ Sbjct: 634 GRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQ 675 >gi|38679890 solute carrier organic anion transporter family, member 4C1 [Homo sapiens] Length = 724 Score = 292 bits (748), Expect = 6e-79 Identities = 177/588 (30%), Positives = 287/588 (48%), Gaps = 35/588 (5%) Query: 23 LLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSYFGTK 82 LLA+T V L +N ++ +E+++ + +SL G I+ S++I LL +FVS+FG + Sbjct: 113 LLAVTQGIVVNGL----VNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFGER 168 Query: 83 LHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCMENGTQILRP 142 H+P + ++GLG + SLP F +Y+ G+L ++ + N T Sbjct: 169 GHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKL-------GSLFEDTCVTTRNSTSC--- 218 Query: 143 TQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIGLVETG 202 + T + + ++V++L G ++ G G TP+ LG ++++D S LYIG Sbjct: 219 ----TSSTSSLSNYLYVFIL-GQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAM 273 Query: 203 AIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIP 262 +I+GP IG +L +Y+D + D +T D RW+GAWW GFL+ IP Sbjct: 274 SILGPAIGYVLGGQLLTIYIDVAMGESTD--VTEDDPRWLGAWWIGFLLSWIFAWSLIIP 331 Query: 263 FFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYGITKDFLPFMKSLSCNPIYMLFI 322 F P LP E A ++ +VK K KDF +K+L N ++M + Sbjct: 332 FSCFPKHLPGTA-EIQAGKTSQAHQSNSNADVKFGKS--IKDFPAALKNLMKNAVFMCLV 388 Query: 323 LVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKI 382 L + + +F+PK++E Q+G++SS A L G +P +G I+GG ++ KF++ Sbjct: 389 LSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVSKFRM 448 Query: 383 TVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEGIPQDLYVENDIFADCNVD 442 T K + S + L F+ CEN G++ SY G + ++ A CN + Sbjct: 449 TCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGE----LGNLIAPCNAN 504 Query: 443 CNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMVFQNCSCIQTS---GNSSAVLGL 499 CNC + PVCG +G+ Y S C AGC + V+ NCSCI+ +++ G Sbjct: 505 CNCSRSYYYPVCG-DGVQYFSPCFAGCSNPVAHRKPKVYYNCSCIERKTEITSTAETFGF 563 Query: 500 CDKGPDCS---LMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTR 556 K C L FL + + +A P + +LRC+ ++SL +G+ R Sbjct: 564 EAKAGKCETHCAKLPIFLCIFFIVIIFTFMAGTPITVSILRCVNHRQRSLALGIQFMVLR 623 Query: 557 VFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGL 604 + IP PI FG +DSTC+ W CG GAC IYD+ ++ + + Sbjct: 624 LLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVAI 671 >gi|225637475 solute carrier organic anion transporter family, member 5A1 isoform 3 [Homo sapiens] Length = 793 Score = 283 bits (723), Expect = 5e-76 Identities = 183/642 (28%), Positives = 307/642 (47%), Gaps = 112/642 (17%) Query: 16 LSKLKMFLLAIT-CAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLII 74 L+ + FL+ + F+ + Y++S++T IER++++ +S G + F+IGNL++++ Sbjct: 124 LTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVV 183 Query: 75 FVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSS-NSFLCM 133 FVSYFG + RP+ + +G +++ G L +LPHF+ Y+ + N S+ N LC Sbjct: 184 FVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQEL-----NASAPNDGLCQ 238 Query: 134 ENGTQILRPTQDPSECTKEVK-SLMWVYV---LVGNIVRGMGETPILPLGISYIEDFAKF 189 + T +P C K+ + WVYV + I+ GMG TPI LG +Y++D K Sbjct: 239 GGNSTA---TLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKK 295 Query: 190 ENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGF 249 ENS LY+ ++ +GP +G LL YVD + + + D R++G WW GF Sbjct: 296 ENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVDP----RNPVHLDQNDPRFIGNWWSGF 351 Query: 250 LICAGVNVLTAIPFFFLPNTLP-------KEGLETNA----DIIKNENEDKQKEEVKKEK 298 L+CA L P F P LP K+ +A D++K ++ + ++ + K Sbjct: 352 LLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSS 411 Query: 299 YGITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLM 358 G KD + Sbjct: 412 MGFGKD----------------------------------------------------VR 419 Query: 359 GIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGI 418 G+ +P +G ++GG I+KK K+ +++A + S + L + F++ CE+ ++ GI Sbjct: 420 GVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGI 479 Query: 419 NTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETS--IGTG 476 N Y P ++ CNV+C C ++PVCG++G++Y + CLAGC S + TG Sbjct: 480 NIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTG 539 Query: 477 INMVFQNCSCIQT------------------------SGNSSAVLGLCDKGPDCSLMLQY 512 I + C+C+Q+ + N AV G C + C+ ++ Sbjct: 540 IRN-YTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKR--TCNTLIP- 595 Query: 513 FLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMD 572 FL+ + +FI + A +V LR ++ EE+ +G+ R A IP PIYFGA++D Sbjct: 596 FLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVID 655 Query: 573 STCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRGSSFV 614 +TC+ W +CG G+C Y+ T+FR++Y GL A L+ F+ Sbjct: 656 TTCMLW-QQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFI 696 >gi|39777594 solute carrier organic anion transporter family member 4A1 [Homo sapiens] Length = 722 Score = 281 bits (718), Expect = 2e-75 Identities = 174/592 (29%), Positives = 287/592 (48%), Gaps = 38/592 (6%) Query: 21 MFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSYFG 80 +F L T++G ++N+++T +ER++++ + G I S++I L + FVSYFG Sbjct: 106 LFFLCAAAFLQGMTVNG-FINTVITSLERRYDLHSYQSGLIASSYDIAACLCLTFVSYFG 164 Query: 81 TKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCMENGTQIL 140 H+P +G G ++MG G + +LPHF +YE E V ++ +C ++ + + Sbjct: 165 GSGHKPRWLGWGVLLMGTGSLVFALPHFTAGRYEVELDAGVRTCPANPGAVCADSTSGLS 224 Query: 141 RPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIGLVE 200 R + ++G + G+G TP+ LG++Y+++ K SP+YI + Sbjct: 225 R---------------YQLVFMLGQFLHGVGATPLYTLGVTYLDENVKSSCSPVYIAIFY 269 Query: 201 TGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTA 260 T AI+GP G L+ N+Y + G +T WVGAWW GFL TA Sbjct: 270 TAAILGPAAGYLIGGALLNIYTEMGRRTE----LTTESPLWVGAWWVGFLGSGAAAFFTA 325 Query: 261 IPFFFLPNTLP-KEGLETNADIIKNENEDKQKEEVKKEKYGITKDFLPF-MKSLSCNPIY 318 +P P LP + ++ +D + E +G T LP + L NP + Sbjct: 326 VPILGYPRQLPGSQRYAVMRAAEMHQLKDSSRGEASNPDFGKTIRDLPLSIWLLLKNPTF 385 Query: 319 MLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMK 378 +L L + M +F PK+LE Q+ +S+S+A L G +P G +GG + Sbjct: 386 ILLCLAGATEATLITGMSTFSPKFLESQFSLSASEAATLFGYLVVPAGGGGTFLGGFFVN 445 Query: 379 KFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEG--IPQDLYVENDIF 436 K ++ C + LL L F + C + + G+ SY G +P+ ++ Sbjct: 446 KLRLRGSAVIKF-CLFCTVVSLLGILVFSLHCPSVPMAGVTASYGGSLLPEG---HLNLT 501 Query: 437 ADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGIN--MVFQNCSCIQ---TSG 491 A CN C+C + + PVCG++GL Y S C AGC + T ++ V+++CSCI +SG Sbjct: 502 APCNAACSCQPEHYSPVCGSDGLMYFSLCHAGCPAATETNVDGQKVYRDCSCIPQNLSSG 561 Query: 492 NSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLH 551 A G C +L F+ + +F L++IP LRC++ ++S +G+ Sbjct: 562 FGHATAGKCTSTCQRKPLLLVFIFVVIFFTF---LSSIPALTATLRCVRDPQRSFALGIQ 618 Query: 552 TFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIY-DSTTFRYIYL 602 R+ GIP PI FG ++D CL W +CG+ G+C +Y +S RYI + Sbjct: 619 WIVVRILGGIPGPIAFGWVIDKACLLWQD-QCGQQGSCLVYQNSAMSRYILI 669 >gi|225637477 solute carrier organic anion transporter family, member 5A1 isoform 2 [Homo sapiens] Length = 687 Score = 259 bits (663), Expect = 4e-69 Identities = 155/496 (31%), Positives = 263/496 (53%), Gaps = 35/496 (7%) Query: 16 LSKLKMFLLAIT-CAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLII 74 L+ + FL+ + F+ + Y++S++T IER++++ +S G + F+IGNL++++ Sbjct: 124 LTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVV 183 Query: 75 FVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSS-NSFLCM 133 FVSYFG + RP+ + +G +++ G L +LPHF+ Y+ + N S+ N LC Sbjct: 184 FVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQEL-----NASAPNDGLCQ 238 Query: 134 ENGTQILRPTQDPSECTKEVK-SLMWVYV---LVGNIVRGMGETPILPLGISYIEDFAKF 189 + T +P C K+ + WVYV + I+ GMG TPI LG +Y++D K Sbjct: 239 GGNSTA---TLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKK 295 Query: 190 ENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGF 249 ENS LY+ ++ +GP +G LL YVD + + + D R++G WW GF Sbjct: 296 ENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVDP----RNPVHLDQNDPRFIGNWWSGF 351 Query: 250 LICAGVNVLTAIPFFFLPNTLP-------KEGLETNA----DIIKNENEDKQKEEVKKEK 298 L+CA L P F P LP K+ +A D++K ++ + ++ + K Sbjct: 352 LLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSS 411 Query: 299 YGITKDF--LPFMKSLSCNPIYMLFILVSVIQFNAFVN-MISFMPKYLEQQYGISSSDAI 355 G KD LP + + LF+ +S +A V I+F+PK++E Q+GI +S+A Sbjct: 412 MGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNAS 471 Query: 356 FLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSV 415 G+ +P +G ++GG I+KK K+ +++A + S + L + F++ CE+ ++ Sbjct: 472 IYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINL 531 Query: 416 VGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETS--I 473 GIN Y P ++ CNV+C C ++PVCG++G++Y + CLAGC S + Sbjct: 532 GGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNL 591 Query: 474 GTGINMVFQNCSCIQT 489 TGI + C+C+Q+ Sbjct: 592 STGIRN-YTECTCVQS 606 >gi|223634014 solute carrier organic anion transporter family, member 2B1 isoform 3 [Homo sapiens] Length = 565 Score = 253 bits (645), Expect = 5e-67 Identities = 153/495 (30%), Positives = 254/495 (51%), Gaps = 41/495 (8%) Query: 161 VLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANV 220 + V + G+G PI P GISYI+DFA NSPLY+G++ ++GP + L S + Sbjct: 48 MFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRL 107 Query: 221 YVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLE---- 276 YVD + + +T D RWVGAWW GFLI AG L AIP+FF P +PKE E Sbjct: 108 YVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFR 167 Query: 277 ------TNADIIKNENEDKQKE--EVKKEKYGIT------------KDFLPFMKSLSCNP 316 T++ K ++ ++ E K++ G+ K F + +P Sbjct: 168 RKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHP 227 Query: 317 IYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLI 376 I++L +L V + M +F+PK+LE+Q+ I++S A L+G + P + +G ++GG++ Sbjct: 228 IFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVL 287 Query: 377 MKKFKITVKQAAHIGCWLSLLEYLLYFLS-FLMTCENSSVVGINTSYEGIPQDLYVENDI 435 +K+ + + C L +L L + L F + C + + GI P ++ Sbjct: 288 VKRLHLGPVGCGAL-CLLGMLLCLFFSLPLFFIGCSSHQIAGITHQTSAHP-----GLEL 341 Query: 436 FADCNVDCNCPSKIWDPVCG-NNGLSYLSACLAGCETSIG----TGINMVFQNCSCIQTS 490 C C+CP ++PVC + + Y++ C AGC + + + + NCSC+ Sbjct: 342 SPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCV-VE 400 Query: 491 GNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGL 550 GN + G CD CS ++ FL+L ++ S + L P +M++LR +K E+K+L VG+ Sbjct: 401 GN-PVLAGSCDS--TCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGI 457 Query: 551 HTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRG 610 R+ A +P+P+ G+ +D+TC+HW L CG CR Y++ R ++GL + Sbjct: 458 QFMFLRILAWMPSPVIHGSAIDTTCVHW-ALSCGRRAVCRYYNNDLLRNRFIGLQFFFKT 516 Query: 611 SSFVPALIILILLRK 625 S + ++L +LR+ Sbjct: 517 GSVICFALVLAVLRQ 531 Score = 30.0 bits (66), Expect = 7.2 Identities = 22/92 (23%), Positives = 41/92 (44%), Gaps = 2/92 (2%) Query: 21 MFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLL-IIFVSYF 79 +FLL + +++ + +ERQF+I S + G ++++ I+ Sbjct: 228 IFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVL 287 Query: 80 GTKLH-RPIMIGIGCVVMGLGCFLKSLPHFLM 110 +LH P+ G C++ L C SLP F + Sbjct: 288 VKRLHLGPVGCGALCLLGMLLCLFFSLPLFFI 319 >gi|93277099 solute carrier organic anion transporter family, member 6A1 [Homo sapiens] Length = 719 Score = 191 bits (486), Expect = 1e-48 Identities = 135/596 (22%), Positives = 261/596 (43%), Gaps = 30/596 (5%) Query: 15 CLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLII 74 C + ++ F++ + + + ++ + ++++ + T + S++I + L+ I Sbjct: 101 CCNNIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAI 160 Query: 75 FVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCME 134 F++++G + + I ++GLG L + P +N+ +S V + +C E Sbjct: 161 FIAFYGDR-KKVIWFVASSFLIGLGSLLCAFPS--INEENKQSKVGIED-------ICEE 210 Query: 135 NGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPL 194 ++ +S + ++G V+G+ P+ LGI++I++ ++ + Sbjct: 211 -----IKVVSGCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGI 265 Query: 195 YIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAG 254 Y+G+ E ++IG +G +L + V +T + + + W+ WW FL A Sbjct: 266 YLGIAECTSMIGYALGYVLGAPLVKVPENT--TSATNTTVNNGSPEWLWTWWINFLFAAV 323 Query: 255 VNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYGIT-KDFLPFMKSLS 313 V T IP PN +P T K + +K K G KD + L Sbjct: 324 VAWCTLIPLSCFPNNMPGS---TRIKARKRKQLHFFDSRLKDLKLGTNIKDLCAALWILM 380 Query: 314 CNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIG 373 NP+ + L ++ + F+P YLE Q+ ++ + A L G+ +P +G ++G Sbjct: 381 KNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLVLIPGGALGQLLG 440 Query: 374 GLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEGIPQDLYVEN 433 G+I+ +++ K S++ +L + C GIN Y+G + Sbjct: 441 GVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINEDYDGTGK----LG 496 Query: 434 DIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMVFQNCSCIQTSGNS 493 ++ A CN C C S I+ +CG + + Y S C AGC S ++ NCSCI+ + Sbjct: 497 NLTAPCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKAQNQKKMYYNCSCIKEGLIT 556 Query: 494 SAVLG-LCDKGP---DCSLMLQYFLILSAMSSFIYS-LAAIPGYMVLLRCMKSEEKSLGV 548 + G D P D I S+ I+S + +P + + R + + +SL + Sbjct: 557 ADAEGDFIDARPGKCDAKCYKLPLFIAFIFSTLIFSGFSGVPIVLAMTRVVPDKLRSLAL 616 Query: 549 GLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGL 604 G+ R+F IP P F +++C+ KCG +G C IY+ T ++ +G+ Sbjct: 617 GVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIYNKTKMAFLLVGI 672 >gi|11863156 RECK protein precursor [Homo sapiens] Length = 971 Score = 36.6 bits (83), Expect = 0.077 Identities = 17/38 (44%), Positives = 23/38 (60%), Gaps = 1/38 (2%) Query: 432 ENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGC 469 E+D + CNC + + PVCG NG +Y SAC+A C Sbjct: 622 EDDRRTFTGLPCNCADQ-FVPVCGQNGRTYPSACIARC 658 >gi|5453652 follistatin isoform FST317 precursor [Homo sapiens] Length = 317 Score = 32.7 bits (73), Expect = 1.1 Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 8/66 (12%) Query: 439 CNVDCNCPSKIWDPVCGNNGLSYLSAC-LAGCETSIGTGINMVFQ-------NCSCIQTS 490 CN C P+ +CGN+G++Y SAC L +G I + ++ +C IQ + Sbjct: 192 CNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCT 251 Query: 491 GNSSAV 496 G + Sbjct: 252 GGKKCL 257 >gi|7242222 follistatin isoform FST344 precursor [Homo sapiens] Length = 344 Score = 32.7 bits (73), Expect = 1.1 Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 8/66 (12%) Query: 439 CNVDCNCPSKIWDPVCGNNGLSYLSAC-LAGCETSIGTGINMVFQ-------NCSCIQTS 490 CN C P+ +CGN+G++Y SAC L +G I + ++ +C IQ + Sbjct: 192 CNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCT 251 Query: 491 GNSSAV 496 G + Sbjct: 252 GGKKCL 257 >gi|54873613 agrin [Homo sapiens] Length = 2045 Score = 32.3 bits (72), Expect = 1.5 Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 8/77 (10%) Query: 443 CNCP---SKIWDPVCGNNGLSYLSAC-LAGCETSIGTGINMV----FQNCSCIQTSGNSS 494 C C S ++DPVCG++G++Y SAC L ++G I + C + Sbjct: 488 CECLQACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPCDRCGQCRFGALCE 547 Query: 495 AVLGLCDKGPDCSLMLQ 511 A G C +C + Q Sbjct: 548 AETGRCVCPSECVALAQ 564 Score = 31.2 bits (69), Expect = 3.2 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 3/39 (7%) Query: 439 CNVDCNCPSKIWDPVCGNNGLSYLSAC---LAGCETSIG 474 C D +C S PVCG++G++Y + C A CE+ G Sbjct: 703 CVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRG 741 >gi|45505132 serine protease inhibitor, Kazal type 1 precursor [Homo sapiens] Length = 79 Score = 32.0 bits (71), Expect = 1.9 Identities = 13/30 (43%), Positives = 20/30 (66%) Query: 437 ADCNVDCNCPSKIWDPVCGNNGLSYLSACL 466 A C + N +KI+DPVCG +G +Y + C+ Sbjct: 30 AKCYNELNGCTKIYDPVCGTDGNTYPNECV 59 >gi|12383051 transmembrane protein with EGF-like and two follistatin-like domains 2 [Homo sapiens] Length = 374 Score = 32.0 bits (71), Expect = 1.9 Identities = 12/32 (37%), Positives = 23/32 (71%), Gaps = 2/32 (6%) Query: 434 DIFADCNVDCNCPSKIWDPVCGNNGLSYLSAC 465 D++ CN+DC+ + ++P+C ++G SY +AC Sbjct: 177 DVWCVCNIDCSQTN--FNPLCASDGKSYDNAC 206 Score = 31.2 bits (69), Expect = 3.2 Identities = 39/155 (25%), Positives = 57/155 (36%), Gaps = 43/155 (27%) Query: 392 CWLSLLEYLLY----------FLSFLMTCENSSVVGINTS-YEGIPQDLYVEND----IF 436 CWL LL +L F + L C+ + G N S Y+ DL++ + Sbjct: 20 CWLLLLPVMLLIVARPVKLAAFPTSLSDCQTPT--GWNCSGYDDRENDLFLCDTNTCKFD 77 Query: 437 ADC-----NVDCNCPSKI---WDPVCGNNGLSYLSACL-----------------AGCET 471 +C V C C K + PVCG+NG SY + C C T Sbjct: 78 GECLRIGDTVTCVCQFKCNNDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCAT 137 Query: 472 SIGTGINMVFQNCSCIQTSGNSSAVLGLCDKGPDC 506 G+G S +TS ++ +C G +C Sbjct: 138 DAGSGSGDGVHEGSG-ETSQKETSTCDICQFGAEC 171 >gi|185134902 olfactory receptor, family 2, subfamily J, member 3 [Homo sapiens] Length = 311 Score = 32.0 bits (71), Expect = 1.9 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 2/58 (3%) Query: 67 IGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCF-LKSLPHFLMNQYEYESTVSVSG 123 IGNL +II +SY + LH P+ + + C+ S+P L+N + E T+S +G Sbjct: 43 IGNLFIII-LSYLDSHLHTPMYFFLSNLSFLDLCYTTSSIPQLLVNLWGPEKTISYAG 99 >gi|5031701 follistatin-like 3 glycoprotein precursor [Homo sapiens] Length = 263 Score = 31.6 bits (70), Expect = 2.5 Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 4/44 (9%) Query: 426 PQDLYVENDIFADCNV----DCNCPSKIWDPVCGNNGLSYLSAC 465 PQ V+ A C V C PS +CGNN ++Y+S+C Sbjct: 179 PQSCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSC 222 >gi|74275344 trace amine associated receptor 2 isoform 1 [Homo sapiens] Length = 351 Score = 31.2 bits (69), Expect = 3.2 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 4/51 (7%) Query: 39 YMNSMLTQIERQFNIPTSLVGFINGSFEI---GNLLLIIFVSYFGTKLHRP 86 Y N + ER + ++ F+ GS I GNL +II +SYF +LH P Sbjct: 28 YGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYF-KQLHTP 77 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.141 0.434 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,618,476 Number of Sequences: 37866 Number of extensions: 1112745 Number of successful extensions: 3583 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 27 Number of HSP's successfully gapped in prelim test: 12 Number of HSP's that attempted gapping in prelim test: 3449 Number of HSP's gapped (non-prelim): 54 length of query: 670 length of database: 18,247,518 effective HSP length: 109 effective length of query: 561 effective length of database: 14,120,124 effective search space: 7921389564 effective search space used: 7921389564 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.5 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.