Guide to the Human Genome
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Search of human proteins with 10835099

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10835099 organic anion transporting polypeptide A [Homo
sapiens]
         (670 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10835099 organic anion transporting polypeptide A [Homo sapiens]  1362   0.0  
gi|19913403 organic anion transporting polypeptide A [Homo sapiens]  1362   0.0  
gi|8394291 solute carrier organic anion transporter family, memb...   615   e-176
gi|225543118 solute carrier organic anion transporter family, me...   603   e-172
gi|225543525 solute carrier organic anion transporter family, me...   542   e-154
gi|225543116 solute carrier organic anion transporter family, me...   540   e-153
gi|9790233 solute carrier organic anion transporter family, memb...   521   e-148
gi|225543114 solute carrier organic anion transporter family, me...   501   e-141
gi|116812593 liver-specific organic anion transporter 3TM12 [Hom...   481   e-135
gi|222831575 solute carrier organic anion transporter family, me...   391   e-108
gi|222831573 solute carrier organic anion transporter family, me...   391   e-108
gi|188528663 solute carrier organic anion transporter family, me...   369   e-102
gi|225637473 solute carrier organic anion transporter family, me...   325   8e-89
gi|223634012 solute carrier organic anion transporter family, me...   325   1e-88
gi|6005820 solute carrier organic anion transporter family, memb...   325   1e-88
gi|38679890 solute carrier organic anion transporter family, mem...   292   6e-79
gi|225637475 solute carrier organic anion transporter family, me...   283   5e-76
gi|39777594 solute carrier organic anion transporter family memb...   281   2e-75
gi|225637477 solute carrier organic anion transporter family, me...   259   4e-69
gi|223634014 solute carrier organic anion transporter family, me...   253   5e-67
gi|93277099 solute carrier organic anion transporter family, mem...   191   1e-48
gi|11863156 RECK protein precursor [Homo sapiens]                      37   0.077
gi|5453652 follistatin isoform FST317 precursor [Homo sapiens]         33   1.1  
gi|7242222 follistatin isoform FST344 precursor [Homo sapiens]         33   1.1  
gi|54873613 agrin [Homo sapiens]                                       32   1.5  
gi|45505132 serine protease inhibitor, Kazal type 1 precursor [H...    32   1.9  
gi|12383051 transmembrane protein with EGF-like and two follista...    32   1.9  
gi|185134902 olfactory receptor, family 2, subfamily J, member 3...    32   1.9  
gi|5031701 follistatin-like 3 glycoprotein precursor [Homo sapiens]    32   2.5  
gi|74275344 trace amine associated receptor 2 isoform 1 [Homo sa...    31   3.2  

>gi|10835099 organic anion transporting polypeptide A [Homo sapiens]
          Length = 670

 Score = 1362 bits (3526), Expect = 0.0
 Identities = 670/670 (100%), Positives = 670/670 (100%)

Query: 1   MGETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGF 60
           MGETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGF
Sbjct: 1   MGETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGF 60

Query: 61  INGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVS 120
           INGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVS
Sbjct: 61  INGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVS 120

Query: 121 VSGNLSSNSFLCMENGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGI 180
           VSGNLSSNSFLCMENGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGI
Sbjct: 121 VSGNLSSNSFLCMENGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGI 180

Query: 181 SYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTR 240
           SYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTR
Sbjct: 181 SYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTR 240

Query: 241 WVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYG 300
           WVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYG
Sbjct: 241 WVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYG 300

Query: 301 ITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGI 360
           ITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGI
Sbjct: 301 ITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGI 360

Query: 361 YNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINT 420
           YNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINT
Sbjct: 361 YNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINT 420

Query: 421 SYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMV 480
           SYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMV
Sbjct: 421 SYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMV 480

Query: 481 FQNCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMK 540
           FQNCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMK
Sbjct: 481 FQNCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMK 540

Query: 541 SEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYI 600
           SEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYI
Sbjct: 541 SEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYI 600

Query: 601 YLGLPAALRGSSFVPALIILILLRKCHLPGENASSGTELIETKVKGKENECKDIYQKSTV 660
           YLGLPAALRGSSFVPALIILILLRKCHLPGENASSGTELIETKVKGKENECKDIYQKSTV
Sbjct: 601 YLGLPAALRGSSFVPALIILILLRKCHLPGENASSGTELIETKVKGKENECKDIYQKSTV 660

Query: 661 LKDDELKTKL 670
           LKDDELKTKL
Sbjct: 661 LKDDELKTKL 670


>gi|19913403 organic anion transporting polypeptide A [Homo sapiens]
          Length = 670

 Score = 1362 bits (3526), Expect = 0.0
 Identities = 670/670 (100%), Positives = 670/670 (100%)

Query: 1   MGETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGF 60
           MGETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGF
Sbjct: 1   MGETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGF 60

Query: 61  INGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVS 120
           INGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVS
Sbjct: 61  INGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVS 120

Query: 121 VSGNLSSNSFLCMENGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGI 180
           VSGNLSSNSFLCMENGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGI
Sbjct: 121 VSGNLSSNSFLCMENGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGI 180

Query: 181 SYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTR 240
           SYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTR
Sbjct: 181 SYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTR 240

Query: 241 WVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYG 300
           WVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYG
Sbjct: 241 WVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYG 300

Query: 301 ITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGI 360
           ITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGI
Sbjct: 301 ITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGI 360

Query: 361 YNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINT 420
           YNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINT
Sbjct: 361 YNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINT 420

Query: 421 SYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMV 480
           SYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMV
Sbjct: 421 SYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMV 480

Query: 481 FQNCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMK 540
           FQNCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMK
Sbjct: 481 FQNCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMK 540

Query: 541 SEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYI 600
           SEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYI
Sbjct: 541 SEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYI 600

Query: 601 YLGLPAALRGSSFVPALIILILLRKCHLPGENASSGTELIETKVKGKENECKDIYQKSTV 660
           YLGLPAALRGSSFVPALIILILLRKCHLPGENASSGTELIETKVKGKENECKDIYQKSTV
Sbjct: 601 YLGLPAALRGSSFVPALIILILLRKCHLPGENASSGTELIETKVKGKENECKDIYQKSTV 660

Query: 661 LKDDELKTKL 670
           LKDDELKTKL
Sbjct: 661 LKDDELKTKL 670


>gi|8394291 solute carrier organic anion transporter family, member
           1C1 isoform 2 [Homo sapiens]
          Length = 712

 Score =  615 bits (1586), Expect = e-176
 Identities = 295/641 (46%), Positives = 426/641 (66%), Gaps = 18/641 (2%)

Query: 3   ETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFIN 62
           +TE      +  C  +LK+FL A++  + +K L+  Y+ S +TQIER+F+IP+SLVG I+
Sbjct: 26  KTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVID 85

Query: 63  GSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVS 122
           GSFEIGNLL+I FVSYFG KLHRP +IG GCV+MG+G  L ++P F M QY+YE     S
Sbjct: 86  GSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS 145

Query: 123 GNLSSNSFLCMENGTQILRPTQDPS------ECTKEVKSLMWVYVLVGNIVRGMGETPIL 176
            +  S S   +E+ +Q+     + S      EC  +  S MW+YV +GN++RG+GETPI 
Sbjct: 146 NSTLSISPCLLESSSQLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQ 205

Query: 177 PLGISYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITP 236
           PLGI+Y++DFA  +N+  YIG V+T AIIGP+ G LL S CA +YVD GFVN D + ITP
Sbjct: 206 PLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITP 265

Query: 237 TDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNAD-------IIKNENEDK 289
            D +WVGAWW G+LI   +++L A+PF++LP +LP+     +++        I +++ D 
Sbjct: 266 KDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDY 325

Query: 290 QKEEVKKEKY-GITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYG 348
           Q  + +  K   + +DFLP +K+L  NP+Y L++  S +QFN+   M+++ PKY+EQQYG
Sbjct: 326 QTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYG 385

Query: 349 ISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLM 408
            SSS A F++G+ N+P + +G   GG++MKKF+I+V  AA +    S+  YLL+   F +
Sbjct: 386 QSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFAL 445

Query: 409 TCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAG 468
            CENS V G+  SY+G     Y E  +F+DCN  C C    W+P+CG NG++Y+SACLAG
Sbjct: 446 GCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAG 505

Query: 469 CETSIGTGINMVFQNCSCI----QTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIY 524
           C+TS  +G N++F NC+C+      SGNSS ++G C K   C  M  YFL++S ++S+  
Sbjct: 506 CQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTL 565

Query: 525 SLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCG 584
           SL  IPGY++LLRC+K + KS  +G++T   RV AGIPAP+YFG L+D++CL WG  +CG
Sbjct: 566 SLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCG 625

Query: 585 ESGACRIYDSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625
             G+CR+YDS  FR+IYLGL   L   S + ++ +L +L+K
Sbjct: 626 SRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKK 666


>gi|225543118 solute carrier organic anion transporter family,
           member 1C1 isoform 1 [Homo sapiens]
          Length = 730

 Score =  603 bits (1554), Expect = e-172
 Identities = 288/623 (46%), Positives = 414/623 (66%), Gaps = 18/623 (2%)

Query: 3   ETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFIN 62
           +TE      +  C  +LK+FL A++  + +K L+  Y+ S +TQIER+F+IP+SLVG I+
Sbjct: 26  KTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVID 85

Query: 63  GSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVS 122
           GSFEIGNLL+I FVSYFG KLHRP +IG GCV+MG+G  L ++P F M QY+YE     S
Sbjct: 86  GSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS 145

Query: 123 GNLSSNSFLCMENGTQILRPTQDPS------ECTKEVKSLMWVYVLVGNIVRGMGETPIL 176
            +  S S   +E+ +Q+     + S      EC  +  S MW+YV +GN++RG+GETPI 
Sbjct: 146 NSTLSISPCLLESSSQLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQ 205

Query: 177 PLGISYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITP 236
           PLGI+Y++DFA  +N+  YIG V+T AIIGP+ G LL S CA +YVD GFVN D + ITP
Sbjct: 206 PLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITP 265

Query: 237 TDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNAD-------IIKNENEDK 289
            D +WVGAWW G+LI   +++L A+PF++LP +LP+     +++        I +++ D 
Sbjct: 266 KDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDY 325

Query: 290 QKEEVKKEKY-GITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYG 348
           Q  + +  K   + +DFLP +K+L  NP+Y L++  S +QFN+   M+++ PKY+EQQYG
Sbjct: 326 QTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYG 385

Query: 349 ISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLM 408
            SSS A F++G+ N+P + +G   GG++MKKF+I+V  AA +    S+  YLL+   F +
Sbjct: 386 QSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFAL 445

Query: 409 TCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAG 468
            CENS V G+  SY+G     Y E  +F+DCN  C C    W+P+CG NG++Y+SACLAG
Sbjct: 446 GCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAG 505

Query: 469 CETSIGTGINMVFQNCSCI----QTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIY 524
           C+TS  +G N++F NC+C+      SGNSS ++G C K   C  M  YFL++S ++S+  
Sbjct: 506 CQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTL 565

Query: 525 SLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCG 584
           SL  IPGY++LLRC+K + KS  +G++T   RV AGIPAP+YFG L+D++CL WG  +CG
Sbjct: 566 SLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCG 625

Query: 585 ESGACRIYDSTTFRYIYLGLPAA 607
             G+CR+YDS  FRY    +PA+
Sbjct: 626 SRGSCRLYDSNVFRYQIKSIPAS 648


>gi|225543525 solute carrier organic anion transporter family,
           member 1B1 [Homo sapiens]
          Length = 691

 Score =  542 bits (1397), Expect = e-154
 Identities = 272/635 (42%), Positives = 401/635 (63%), Gaps = 20/635 (3%)

Query: 9   ETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIG 68
           E  + R  + LKMFL A++ +F++KTL    M S +  IER+F I +SLVGFI+GSFEIG
Sbjct: 17  ENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFEIG 76

Query: 69  NLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEY--ESTVSVSGNLS 126
           NLL+I+FVSYFG+KLHRP +IGIGC +MG+G  L +LPHF M  Y Y  E+ ++ S N +
Sbjct: 77  NLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSSENST 136

Query: 127 SNSFLCMENGTQILRPTQDPSE-----CTKEVKSLMWVYVLVGNIVRGMGETPILPLGIS 181
           S    C+ N  QIL   +   E     C KE  S MW+YV +GN++RG+GETPI+PLG+S
Sbjct: 137 STLSTCLIN--QILSLNRASPEIVGKGCLKESGSYMWIYVFMGNMLRGIGETPIVPLGLS 194

Query: 182 YIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRW 241
           YI+DFAK  +S LY+G++   A+IGP+IG  L S  + +YVD G+V+   + ITPTD+RW
Sbjct: 195 YIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRW 254

Query: 242 VGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNAD----IIKNENEDKQKEEVKKE 297
           VGAWW  FL+    +++++IPFFFLP T  K   E  A     +++  +E  Q   +  +
Sbjct: 255 VGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLETNDEKDQTANLTNQ 314

Query: 298 KYGITKD---FLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDA 354
              ITK+   F    KS+  NP+Y++F+L++++Q ++++   +++ KY+EQQYG  SS A
Sbjct: 315 GKNITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKA 374

Query: 355 IFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSS 414
             L+G+  +P    G  +GG I+KKFK+     A   C+ +++    Y L F + CEN S
Sbjct: 375 NILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKS 434

Query: 415 VVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIG 474
           V G+  +Y+G        +   + CN DCNC    W+PVCGNNG++Y+S CLAGC++S G
Sbjct: 435 VAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSG 494

Query: 475 TGINMVFQNCSCIQTSG----NSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIP 530
               +VF NCSC++ +G    N SA LG C +   C+    +F+ +  ++ F  +L    
Sbjct: 495 NKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGTS 554

Query: 531 GYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACR 590
             M++++ ++ E KSL +G H+   R   GI APIYFGAL+D+TC+ W T  CG  G+CR
Sbjct: 555 HVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSCR 614

Query: 591 IYDSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625
            Y+ST+F  +YLGL + LR SS V  +I++  ++K
Sbjct: 615 TYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKK 649


>gi|225543116 solute carrier organic anion transporter family,
           member 1C1 isoform 3 [Homo sapiens]
          Length = 663

 Score =  540 bits (1390), Expect = e-153
 Identities = 274/635 (43%), Positives = 394/635 (62%), Gaps = 55/635 (8%)

Query: 3   ETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFIN 62
           +TE      +  C  +LK+FL A++  + +K L+  Y+ S +TQIER+F+IP+SLVG I+
Sbjct: 26  KTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVID 85

Query: 63  GSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVS 122
           GSFEIGNLL+I FVSYFG KLHRP +IG GCV+MG+G  L ++P F M QY+YE      
Sbjct: 86  GSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERY---- 141

Query: 123 GNLSSNSFLCMENGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISY 182
            + SSNS L +             S C  E  S + V V+                    
Sbjct: 142 -SPSSNSTLSI-------------SPCLLESSSQLPVSVM-------------------- 167

Query: 183 IEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWV 242
                +   S +  G V+T AIIGP+ G LL S CA +YVD GFVN D + ITP D +WV
Sbjct: 168 -----EKSKSKISNGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWV 222

Query: 243 GAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNAD-------IIKNENEDKQKEEVK 295
           GAWW G+LI   +++L A+PF++LP +LP+     +++        I +++ D Q  + +
Sbjct: 223 GAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGE 282

Query: 296 KEKY-GITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDA 354
             K   + +DFLP +K+L  NP+Y L++  S +QFN+   M+++ PKY+EQQYG SSS A
Sbjct: 283 NAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRA 342

Query: 355 IFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSS 414
            F++G+ N+P + +G   GG++MKKF+I+V  AA +    S+  YLL+   F + CENS 
Sbjct: 343 NFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSD 402

Query: 415 VVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIG 474
           V G+  SY+G     Y E  +F+DCN  C C    W+P+CG NG++Y+SACLAGC+TS  
Sbjct: 403 VAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNR 462

Query: 475 TGINMVFQNCSCI----QTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIP 530
           +G N++F NC+C+      SGNSS ++G C K   C  M  YFL++S ++S+  SL  IP
Sbjct: 463 SGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIP 522

Query: 531 GYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACR 590
           GY++LLRC+K + KS  +G++T   RV AGIPAP+YFG L+D++CL WG  +CG  G+CR
Sbjct: 523 GYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCR 582

Query: 591 IYDSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625
           +YDS  FR+IYLGL   L   S + ++ +L +L+K
Sbjct: 583 LYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKK 617


>gi|9790233 solute carrier organic anion transporter family, member
           1B3 [Homo sapiens]
          Length = 702

 Score =  521 bits (1342), Expect = e-148
 Identities = 261/633 (41%), Positives = 393/633 (62%), Gaps = 16/633 (2%)

Query: 9   ETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIG 68
           E  + R  +  KMFL A++ ++++K L G  M   +TQIER+F+I +SL G I+GSFEIG
Sbjct: 17  EKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGLIDGSFEIG 76

Query: 69  NLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEY--ESTVSVSGNLS 126
           NLL+I+FVSYFG+KLHRP +IGIGC++MG G  L SLPHF M  Y Y  E+ ++ S N +
Sbjct: 77  NLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGYYRYSKETHINPSENST 136

Query: 127 SNSFLCMENGTQILRPTQDP---SECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYI 183
           S+   C+ N T     T       +C KE  S MW+YV +GN++RG+GETPI+PLGISYI
Sbjct: 137 SSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWIYVFMGNMLRGIGETPIVPLGISYI 196

Query: 184 EDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVG 243
           +DFAK  +S LY+G +    +IGP+IG  L S  A +YVD G+V+   + ITP D+RWVG
Sbjct: 197 DDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLSTIRITPKDSRWVG 256

Query: 244 AWWFGFLICAGVNVLTAIPFFFLPNTLPK----EGLETNADIIKNENEDKQKEEVKKEKY 299
           AWW GFL+    +++++IPFFFLP    K      +  +  ++K  ++  Q   +  +  
Sbjct: 257 AWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLKTNDDRNQTANLTNQGK 316

Query: 300 GITKD---FLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIF 356
            +TK+   F   +KS+  NP+Y++F+L++++Q ++F+   +++ KY+EQQYG S+S A F
Sbjct: 317 NVTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANF 376

Query: 357 LMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVV 416
           L+GI  +P +  G  +GG I+KKFK+++   A      S++ +L   L F + CE+ SV 
Sbjct: 377 LLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVA 436

Query: 417 GINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTG 476
           G+  +Y+G        +   + CN +CNC    W+PVCGNNG++YLS CLAGC++S G  
Sbjct: 437 GLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGIK 496

Query: 477 INMVFQNCSCIQTSG----NSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGY 532
            + VF NCSC++ +G    N SA LG C +   C+     ++ +  ++S   +       
Sbjct: 497 KHTVFYNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSLFSATGGTTFI 556

Query: 533 MVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIY 592
           ++ ++ ++ E K+L +G  +   R   GI APIYFGAL+D TC+ W T  CG  GACRIY
Sbjct: 557 LLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNSCGAQGACRIY 616

Query: 593 DSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625
           +S  F  +YLGL  ALR  + V  ++ +  ++K
Sbjct: 617 NSVFFGRVYLGLSIALRFPALVLYIVFIFAMKK 649


>gi|225543114 solute carrier organic anion transporter family,
           member 1C1 isoform 4 [Homo sapiens]
          Length = 612

 Score =  501 bits (1289), Expect = e-141
 Identities = 237/530 (44%), Positives = 345/530 (65%), Gaps = 18/530 (3%)

Query: 96  MGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCMENGTQILRPTQDPS------EC 149
           MG+G  L ++P F M QY+YE     S +  S S   +E+ +Q+     + S      EC
Sbjct: 1   MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC 60

Query: 150 TKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIGLVETGAIIGPLI 209
             +  S MW+YV +GN++RG+GETPI PLGI+Y++DFA  +N+  YIG V+T AIIGP+ 
Sbjct: 61  EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF 120

Query: 210 GLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNT 269
           G LL S CA +YVD GFVN D + ITP D +WVGAWW G+LI   +++L A+PF++LP +
Sbjct: 121 GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS 180

Query: 270 LPKEGLETNAD-------IIKNENEDKQKEEVKKEKY-GITKDFLPFMKSLSCNPIYMLF 321
           LP+     +++        I +++ D Q  + +  K   + +DFLP +K+L  NP+Y L+
Sbjct: 181 LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY 240

Query: 322 ILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFK 381
           +  S +QFN+   M+++ PKY+EQQYG SSS A F++G+ N+P + +G   GG++MKKF+
Sbjct: 241 LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR 300

Query: 382 ITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEGIPQDLYVENDIFADCNV 441
           I+V  AA +    S+  YLL+   F + CENS V G+  SY+G     Y E  +F+DCN 
Sbjct: 301 ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS 360

Query: 442 DCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMVFQNCSCI----QTSGNSSAVL 497
            C C    W+P+CG NG++Y+SACLAGC+TS  +G N++F NC+C+      SGNSS ++
Sbjct: 361 RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV 420

Query: 498 GLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRV 557
           G C K   C  M  YFL++S ++S+  SL  IPGY++LLRC+K + KS  +G++T   RV
Sbjct: 421 GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV 480

Query: 558 FAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAA 607
            AGIPAP+YFG L+D++CL WG  +CG  G+CR+YDS  FRY    +PA+
Sbjct: 481 LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRYQIKSIPAS 530


>gi|116812593 liver-specific organic anion transporter 3TM12 [Homo
           sapiens]
          Length = 640

 Score =  481 bits (1237), Expect = e-135
 Identities = 250/605 (41%), Positives = 371/605 (61%), Gaps = 22/605 (3%)

Query: 40  MNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLG 99
           M    TQIER+F I +SLVG I+GSFEIGNL +I+FVSYFG+KLHRP +IGIGC +MG G
Sbjct: 1   MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60

Query: 100 CFLKSLPHFLMNQYEY--ESTVSVSGNLSSNSFLCMENGTQILRPTQDPSE-----CTKE 152
             L +LPHF M  Y Y  E+ +  S N +SN   C+ N  Q+L   + PSE     C KE
Sbjct: 61  SILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLIN--QMLSLNRTPSEIIERGCVKE 118

Query: 153 VKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIGLVETGAIIGPLIGLL 212
             S MW+YV +GN++RG+GETPI+PLGISYI+DFAK  +S LY+G V    + G +   +
Sbjct: 119 SGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFM 178

Query: 213 LASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNTLPK 272
           L S  A +YVD G+V+   + ITP D+RWVGAWW GFL+   V+++++IPFFFLP    K
Sbjct: 179 LGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNK 238

Query: 273 EGLETNAD----IIKNENEDKQKEEVKKEKYGITKD---FLPFMKSLSCNPIYMLFILVS 325
              E        ++K  ++  Q   +   +  ITK+   F   +KS+  NP+Y++F++ +
Sbjct: 239 PQKERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVIFT 298

Query: 326 VIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVK 385
           ++  ++++  ++++ K +EQQYG S+S   FL+G+  LP + IG   GG I+KKFK+++ 
Sbjct: 299 LLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLV 358

Query: 386 QAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEG-IPQDLYVENDIFADCNVDCN 444
             A +    + +  L   L F + CE+ SV G+  +Y+G  P   +V+  + + CN +CN
Sbjct: 359 GLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPL-SYCNSECN 417

Query: 445 CPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMVFQNCSCIQTSG----NSSAVLGLC 500
           C    W+PVCGNNG++YLS CLAGC++S G    +VF NCSC++  G    N SA LG C
Sbjct: 418 CDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSAHLGEC 477

Query: 501 DKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAG 560
            +   C+     + ++  + +F+ ++      ++++R ++ E K+L +G H+   R   G
Sbjct: 478 PRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGG 537

Query: 561 IPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRGSSFVPALIIL 620
           I  PIYFGAL+D+TC+ W T  CG  GACRIY+ST     + GL  AL     V   + +
Sbjct: 538 ILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTVFI 597

Query: 621 ILLRK 625
            ++RK
Sbjct: 598 FVVRK 602


>gi|222831575 solute carrier organic anion transporter family,
           member 3A1 isoform 1 [Homo sapiens]
          Length = 710

 Score =  391 bits (1004), Expect = e-108
 Identities = 213/620 (34%), Positives = 343/620 (55%), Gaps = 29/620 (4%)

Query: 12  RIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLL 71
           ++ C S +K+FL++     +++   G+Y+ S+LT +ER+FN+ ++ VG I  SFEIGNL 
Sbjct: 32  KVSCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNLA 91

Query: 72  LIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFL 131
           LI+FVSYFG + HRP +IG G +VM LG  L +LP FL +QY+YE+     G  +    +
Sbjct: 92  LILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWG--AEGRDV 149

Query: 132 CMENGTQILRPTQDPSECTKEVKSLMWVYVLVG-NIVRGMGETPILPLGISYIEDFAKFE 190
           C  NG+           C     + M   +L+G  ++ G+G TP+ PLG+SYI+D  + +
Sbjct: 150 CAANGSGGDEGPDPDLICRNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRK 209

Query: 191 NSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFL 250
           +S LYIG++ T  + GP  G +L SFC  +YVD  F++T +L ITP D RW+GAWW GFL
Sbjct: 210 DSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFL 269

Query: 251 ICAGVNVLTAIPFFFLPNTLP---KEGLETNADIIKNENEDKQKEEVKKEKYGITKD--- 304
           +C  +   +++  F  P +LP   +  +E+   ++     ++ K      ++ +  D   
Sbjct: 270 LCGALLFFSSLLMFGFPQSLPPHSEPAMESEQAMLSEREYERPKPSNGVLRHPLEPDSSA 329

Query: 305 -------FLP-FMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIF 356
                   +P   K L  NP++   IL + ++        +F+ KYLEQQ+ +++S A  
Sbjct: 330 SCFQQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQ 389

Query: 357 LMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVV 416
           L+G+  +P  C+G  +GGL++KK  ++   A  +   ++L+    Y     + C+   V 
Sbjct: 390 LLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVA 449

Query: 417 GINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTG 476
           G+   Y G         D ++ CN +C C +  + PVCG +G++YLSAC AGC ++  TG
Sbjct: 450 GVTVPY-GNSTAPGSALDPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNSTNLTG 508

Query: 477 INMVFQNCSCIQT--SGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMV 534
                  C+C+ T  + N++ V G C   P C      FL +  + S I ++A  P  ++
Sbjct: 509 -------CACLTTVPAENATVVPGKC-PSPGCQEAFLTFLCVMCICSLIGAMAQTPSVII 560

Query: 535 LLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDS 594
           L+R +  E KS  +G+     R+   IP P+ FGA +DSTCL W T  CGE GAC +YD+
Sbjct: 561 LIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTF-CGEQGACVLYDN 619

Query: 595 TTFRYIYLGLPAALRGSSFV 614
             +RY+Y+ +  AL+  +F+
Sbjct: 620 VVYRYLYVSIAIALKSFAFI 639


>gi|222831573 solute carrier organic anion transporter family,
           member 3A1 isoform 2 [Homo sapiens]
          Length = 692

 Score =  391 bits (1004), Expect = e-108
 Identities = 213/620 (34%), Positives = 343/620 (55%), Gaps = 29/620 (4%)

Query: 12  RIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLL 71
           ++ C S +K+FL++     +++   G+Y+ S+LT +ER+FN+ ++ VG I  SFEIGNL 
Sbjct: 32  KVSCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNLA 91

Query: 72  LIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFL 131
           LI+FVSYFG + HRP +IG G +VM LG  L +LP FL +QY+YE+     G  +    +
Sbjct: 92  LILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWG--AEGRDV 149

Query: 132 CMENGTQILRPTQDPSECTKEVKSLMWVYVLVG-NIVRGMGETPILPLGISYIEDFAKFE 190
           C  NG+           C     + M   +L+G  ++ G+G TP+ PLG+SYI+D  + +
Sbjct: 150 CAANGSGGDEGPDPDLICRNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRK 209

Query: 191 NSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFL 250
           +S LYIG++ T  + GP  G +L SFC  +YVD  F++T +L ITP D RW+GAWW GFL
Sbjct: 210 DSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFL 269

Query: 251 ICAGVNVLTAIPFFFLPNTLP---KEGLETNADIIKNENEDKQKEEVKKEKYGITKD--- 304
           +C  +   +++  F  P +LP   +  +E+   ++     ++ K      ++ +  D   
Sbjct: 270 LCGALLFFSSLLMFGFPQSLPPHSEPAMESEQAMLSEREYERPKPSNGVLRHPLEPDSSA 329

Query: 305 -------FLP-FMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIF 356
                   +P   K L  NP++   IL + ++        +F+ KYLEQQ+ +++S A  
Sbjct: 330 SCFQQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQ 389

Query: 357 LMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVV 416
           L+G+  +P  C+G  +GGL++KK  ++   A  +   ++L+    Y     + C+   V 
Sbjct: 390 LLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVA 449

Query: 417 GINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTG 476
           G+   Y G         D ++ CN +C C +  + PVCG +G++YLSAC AGC ++  TG
Sbjct: 450 GVTVPY-GNSTAPGSALDPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNSTNLTG 508

Query: 477 INMVFQNCSCIQT--SGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMV 534
                  C+C+ T  + N++ V G C   P C      FL +  + S I ++A  P  ++
Sbjct: 509 -------CACLTTVPAENATVVPGKC-PSPGCQEAFLTFLCVMCICSLIGAMAQTPSVII 560

Query: 535 LLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDS 594
           L+R +  E KS  +G+     R+   IP P+ FGA +DSTCL W T  CGE GAC +YD+
Sbjct: 561 LIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTF-CGEQGACVLYDN 619

Query: 595 TTFRYIYLGLPAALRGSSFV 614
             +RY+Y+ +  AL+  +F+
Sbjct: 620 VVYRYLYVSIAIALKSFAFI 639


>gi|188528663 solute carrier organic anion transporter family,
           member 2A1 [Homo sapiens]
          Length = 643

 Score =  369 bits (947), Expect = e-102
 Identities = 215/602 (35%), Positives = 324/602 (53%), Gaps = 39/602 (6%)

Query: 19  LKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSY 78
           +K+F+L      + + L  +Y  S LT IE++F + +S  G I+   EI N +LIIFVSY
Sbjct: 31  IKVFVLCQGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNAILIIFVSY 90

Query: 79  FGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCMENGTQ 138
           FG+++HRP +IGIG + +  G F+ +LPHFL   Y+Y  T++ +GN S       +   Q
Sbjct: 91  FGSRVHRPRLIGIGGLFLAAGAFILTLPHFLSEPYQY--TLASTGNNSRLQAELCQKHWQ 148

Query: 139 ILRP------TQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENS 192
            L P      TQ+P + T    S MW  ++V  ++ G+G  PI P GISY++DF++  NS
Sbjct: 149 DLPPSKCHSTTQNPQKET----SSMWGLMVVAQLLAGIGTVPIQPFGISYVDDFSEPSNS 204

Query: 193 PLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLIC 252
           PLYI ++   ++ GP  G LL S    ++VD G VNT  + + P D RW+GAWW G LI 
Sbjct: 205 PLYISILFAISVFGPAFGYLLGSVMLQIFVDYGRVNTAAVNLVPGDPRWIGAWWLGLLIS 264

Query: 253 AGVNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYGITKDFLP----F 308
           + + VLT+ PFFF P  +P       A      +E ++ EE K    G   DF+      
Sbjct: 265 SALLVLTSFPFFFFPRAMPIGAKRAPA----TADEARKLEEAKSR--GSLVDFIKRFPCI 318

Query: 309 MKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICI 368
              L  N +++L +L      +    + +F+ K+LE+QYG S++ A FL+G  NLP   +
Sbjct: 319 FLRLLMNSLFVLVVLAQCTFSSVIAGLSTFLNKFLEKQYGTSAAYANFLIGAVNLPAAAL 378

Query: 369 GYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGI---NTSYEGI 425
           G + GG++MK+F  +++    I   +  +  +L    F M C   +V  +   +TS    
Sbjct: 379 GMLFGGILMKRFVFSLQAIPRIATTIITISMILCVPLFFMGCSTPTVAEVYPPSTSSSIH 438

Query: 426 PQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCET---SIGTGINMVFQ 482
           PQ           C  DC+CP  I+ PVCG+NG+ YLS C AGC     S  T   +++ 
Sbjct: 439 PQS--------PACRRDCSCPDSIFHPVCGDNGIEYLSPCHAGCSNINMSSATSKQLIYL 490

Query: 483 NCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSE 542
           NCSC+ T G++SA  G C     C+  L   + L +  S I  ++  P YM++LR +  E
Sbjct: 491 NCSCV-TGGSASAKTGSCP--VPCAHFLLPAIFLISFVSLIACISHNPLYMMVLRVVNQE 547

Query: 543 EKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYL 602
           EKS  +G+     R+ A +P+P  +G  +D +C+ W +L  G  GAC  YD+   R  YL
Sbjct: 548 EKSFAIGVQFLLMRLLAWLPSPALYGLTIDHSCIRWNSLCLGRRGACAYYDNDALRDRYL 607

Query: 603 GL 604
           GL
Sbjct: 608 GL 609


>gi|225637473 solute carrier organic anion transporter family,
           member 5A1 isoform 1 [Homo sapiens]
          Length = 848

 Score =  325 bits (833), Expect = 8e-89
 Identities = 200/645 (31%), Positives = 335/645 (51%), Gaps = 63/645 (9%)

Query: 16  LSKLKMFLLAIT-CAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLII 74
           L+  + FL+ +    F+   +   Y++S++T IER++++ +S  G +   F+IGNL++++
Sbjct: 124 LTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVV 183

Query: 75  FVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSS-NSFLCM 133
           FVSYFG +  RP+ + +G +++  G  L +LPHF+   Y+ +       N S+ N  LC 
Sbjct: 184 FVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQEL-----NASAPNDGLCQ 238

Query: 134 ENGTQILRPTQDPSECTKEVK-SLMWVYV---LVGNIVRGMGETPILPLGISYIEDFAKF 189
              +     T +P  C K+   +  WVYV   +   I+ GMG TPI  LG +Y++D  K 
Sbjct: 239 GGNSTA---TLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKK 295

Query: 190 ENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGF 249
           ENS LY+ ++     +GP +G LL       YVD      + + +   D R++G WW GF
Sbjct: 296 ENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVDP----RNPVHLDQNDPRFIGNWWSGF 351

Query: 250 LICAGVNVLTAIPFFFLPNTLP-------KEGLETNA----DIIKNENEDKQKEEVKKEK 298
           L+CA    L   P F  P  LP       K+    +A    D++K ++ + ++ + K   
Sbjct: 352 LLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSS 411

Query: 299 YGITKDF--LPFMKSLSCNPIYMLFILVSVIQFNAFVN-MISFMPKYLEQQYGISSSDAI 355
            G  KD   LP       + +  LF+ +S    +A V   I+F+PK++E Q+GI +S+A 
Sbjct: 412 MGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNAS 471

Query: 356 FLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSV 415
              G+  +P   +G ++GG I+KK K+  +++A +    S +  L +   F++ CE+ ++
Sbjct: 472 IYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINL 531

Query: 416 VGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETS--I 473
            GIN  Y   P       ++   CNV+C C    ++PVCG++G++Y + CLAGC  S  +
Sbjct: 532 GGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNL 591

Query: 474 GTGINMVFQNCSCIQT------------------------SGNSSAVLGLCDKGPDCSLM 509
            TGI   +  C+C+Q+                        + N  AV G C +   C+ +
Sbjct: 592 STGIRN-YTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKR--TCNTL 648

Query: 510 LQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGA 569
           +  FL+   + +FI + A     +V LR ++ EE+   +G+     R  A IP PIYFGA
Sbjct: 649 IP-FLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGA 707

Query: 570 LMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRGSSFV 614
           ++D+TC+ W   +CG  G+C  Y+ T+FR++Y GL A L+   F+
Sbjct: 708 VIDTTCMLW-QQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFI 751


>gi|223634012 solute carrier organic anion transporter family,
           member 2B1 isoform 2 [Homo sapiens]
          Length = 687

 Score =  325 bits (832), Expect = 1e-88
 Identities = 197/642 (30%), Positives = 333/642 (51%), Gaps = 49/642 (7%)

Query: 19  LKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSY 78
           +K+F+L  +   +++ +   Y+ S ++ +E++F + +   G +    E+GN  LI+FVSY
Sbjct: 26  IKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSY 85

Query: 79  FGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCMENGTQ 138
           FG+++HRP MIG G +++ L   L +LPHF+   Y Y++T          + LC+   + 
Sbjct: 86  FGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSA 145

Query: 139 ILRPTQDPSE--CTK--EVKSLMWVYVL-VGNIVRGMGETPILPLGISYIEDFAKFENSP 193
              P   PS   C+   E + L  V ++ V   + G+G  PI P GISYI+DFA   NSP
Sbjct: 146 ---PASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSP 202

Query: 194 LYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICA 253
           LY+G++    ++GP +   L S    +YVD   +    + +T  D RWVGAWW GFLI A
Sbjct: 203 LYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAA 262

Query: 254 GVNVLTAIPFFFLPNTLPKEGLE----------TNADIIKNENEDKQKE--EVKKEKYGI 301
           G   L AIP+FF P  +PKE  E          T++   K ++   ++   E  K++ G+
Sbjct: 263 GAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGL 322

Query: 302 T------------KDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGI 349
                        K F   +     +PI++L +L  V   +    M +F+PK+LE+Q+ I
Sbjct: 323 VQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSI 382

Query: 350 SSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLS-FLM 408
           ++S A  L+G  + P + +G ++GG+++K+  +       + C L +L  L + L  F +
Sbjct: 383 TASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGAL-CLLGMLLCLFFSLPLFFI 441

Query: 409 TCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCG-NNGLSYLSACLA 467
            C +  + GI       P       ++   C   C+CP   ++PVC  +  + Y++ C A
Sbjct: 442 GCSSHQIAGITHQTSAHP-----GLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHA 496

Query: 468 GCETSIG----TGINMVFQNCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFI 523
           GC + +         + + NCSC+   GN   + G CD    CS ++  FL+L ++ S +
Sbjct: 497 GCSSWVVQDALDNSQVFYTNCSCV-VEGN-PVLAGSCDS--TCSHLVVPFLLLVSLGSAL 552

Query: 524 YSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKC 583
             L   P +M++LR +K E+K+L VG+     R+ A +P+P+  G+ +D+TC+HW  L C
Sbjct: 553 ACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHW-ALSC 611

Query: 584 GESGACRIYDSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625
           G    CR Y++   R  ++GL    +  S +   ++L +LR+
Sbjct: 612 GRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQ 653


>gi|6005820 solute carrier organic anion transporter family, member
           2B1 isoform 1 [Homo sapiens]
          Length = 709

 Score =  325 bits (832), Expect = 1e-88
 Identities = 197/642 (30%), Positives = 333/642 (51%), Gaps = 49/642 (7%)

Query: 19  LKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSY 78
           +K+F+L  +   +++ +   Y+ S ++ +E++F + +   G +    E+GN  LI+FVSY
Sbjct: 48  IKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSY 107

Query: 79  FGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCMENGTQ 138
           FG+++HRP MIG G +++ L   L +LPHF+   Y Y++T          + LC+   + 
Sbjct: 108 FGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSA 167

Query: 139 ILRPTQDPSE--CTK--EVKSLMWVYVL-VGNIVRGMGETPILPLGISYIEDFAKFENSP 193
              P   PS   C+   E + L  V ++ V   + G+G  PI P GISYI+DFA   NSP
Sbjct: 168 ---PASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSP 224

Query: 194 LYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICA 253
           LY+G++    ++GP +   L S    +YVD   +    + +T  D RWVGAWW GFLI A
Sbjct: 225 LYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAA 284

Query: 254 GVNVLTAIPFFFLPNTLPKEGLE----------TNADIIKNENEDKQKE--EVKKEKYGI 301
           G   L AIP+FF P  +PKE  E          T++   K ++   ++   E  K++ G+
Sbjct: 285 GAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGL 344

Query: 302 T------------KDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGI 349
                        K F   +     +PI++L +L  V   +    M +F+PK+LE+Q+ I
Sbjct: 345 VQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSI 404

Query: 350 SSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLS-FLM 408
           ++S A  L+G  + P + +G ++GG+++K+  +       + C L +L  L + L  F +
Sbjct: 405 TASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGAL-CLLGMLLCLFFSLPLFFI 463

Query: 409 TCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCG-NNGLSYLSACLA 467
            C +  + GI       P       ++   C   C+CP   ++PVC  +  + Y++ C A
Sbjct: 464 GCSSHQIAGITHQTSAHP-----GLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHA 518

Query: 468 GCETSIG----TGINMVFQNCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFI 523
           GC + +         + + NCSC+   GN   + G CD    CS ++  FL+L ++ S +
Sbjct: 519 GCSSWVVQDALDNSQVFYTNCSCV-VEGN-PVLAGSCDS--TCSHLVVPFLLLVSLGSAL 574

Query: 524 YSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKC 583
             L   P +M++LR +K E+K+L VG+     R+ A +P+P+  G+ +D+TC+HW  L C
Sbjct: 575 ACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHW-ALSC 633

Query: 584 GESGACRIYDSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625
           G    CR Y++   R  ++GL    +  S +   ++L +LR+
Sbjct: 634 GRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQ 675


>gi|38679890 solute carrier organic anion transporter family, member
           4C1 [Homo sapiens]
          Length = 724

 Score =  292 bits (748), Expect = 6e-79
 Identities = 177/588 (30%), Positives = 287/588 (48%), Gaps = 35/588 (5%)

Query: 23  LLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSYFGTK 82
           LLA+T   V   L    +N  ++ +E+++ + +SL G I+ S++I   LL +FVS+FG +
Sbjct: 113 LLAVTQGIVVNGL----VNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFGER 168

Query: 83  LHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCMENGTQILRP 142
            H+P  +     ++GLG  + SLP F   +Y+        G+L  ++ +   N T     
Sbjct: 169 GHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKL-------GSLFEDTCVTTRNSTSC--- 218

Query: 143 TQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIGLVETG 202
               +  T  + + ++V++L G ++ G G TP+  LG ++++D      S LYIG     
Sbjct: 219 ----TSSTSSLSNYLYVFIL-GQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAM 273

Query: 203 AIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIP 262
           +I+GP IG +L      +Y+D     + D  +T  D RW+GAWW GFL+         IP
Sbjct: 274 SILGPAIGYVLGGQLLTIYIDVAMGESTD--VTEDDPRWLGAWWIGFLLSWIFAWSLIIP 331

Query: 263 FFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYGITKDFLPFMKSLSCNPIYMLFI 322
           F   P  LP    E  A      ++     +VK  K    KDF   +K+L  N ++M  +
Sbjct: 332 FSCFPKHLPGTA-EIQAGKTSQAHQSNSNADVKFGKS--IKDFPAALKNLMKNAVFMCLV 388

Query: 323 LVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKI 382
           L +  +        +F+PK++E Q+G++SS A  L G   +P   +G I+GG ++ KF++
Sbjct: 389 LSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVSKFRM 448

Query: 383 TVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEGIPQDLYVENDIFADCNVD 442
           T K       + S +   L F+     CEN    G++ SY G  +      ++ A CN +
Sbjct: 449 TCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGE----LGNLIAPCNAN 504

Query: 443 CNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMVFQNCSCIQTS---GNSSAVLGL 499
           CNC    + PVCG +G+ Y S C AGC   +      V+ NCSCI+      +++   G 
Sbjct: 505 CNCSRSYYYPVCG-DGVQYFSPCFAGCSNPVAHRKPKVYYNCSCIERKTEITSTAETFGF 563

Query: 500 CDKGPDCS---LMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTR 556
             K   C      L  FL +  +      +A  P  + +LRC+   ++SL +G+     R
Sbjct: 564 EAKAGKCETHCAKLPIFLCIFFIVIIFTFMAGTPITVSILRCVNHRQRSLALGIQFMVLR 623

Query: 557 VFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGL 604
           +   IP PI FG  +DSTC+ W    CG  GAC IYD+    ++ + +
Sbjct: 624 LLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVAI 671


>gi|225637475 solute carrier organic anion transporter family,
           member 5A1 isoform 3 [Homo sapiens]
          Length = 793

 Score =  283 bits (723), Expect = 5e-76
 Identities = 183/642 (28%), Positives = 307/642 (47%), Gaps = 112/642 (17%)

Query: 16  LSKLKMFLLAIT-CAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLII 74
           L+  + FL+ +    F+   +   Y++S++T IER++++ +S  G +   F+IGNL++++
Sbjct: 124 LTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVV 183

Query: 75  FVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSS-NSFLCM 133
           FVSYFG +  RP+ + +G +++  G  L +LPHF+   Y+ +       N S+ N  LC 
Sbjct: 184 FVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQEL-----NASAPNDGLCQ 238

Query: 134 ENGTQILRPTQDPSECTKEVK-SLMWVYV---LVGNIVRGMGETPILPLGISYIEDFAKF 189
              +     T +P  C K+   +  WVYV   +   I+ GMG TPI  LG +Y++D  K 
Sbjct: 239 GGNSTA---TLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKK 295

Query: 190 ENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGF 249
           ENS LY+ ++     +GP +G LL       YVD      + + +   D R++G WW GF
Sbjct: 296 ENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVDP----RNPVHLDQNDPRFIGNWWSGF 351

Query: 250 LICAGVNVLTAIPFFFLPNTLP-------KEGLETNA----DIIKNENEDKQKEEVKKEK 298
           L+CA    L   P F  P  LP       K+    +A    D++K ++ + ++ + K   
Sbjct: 352 LLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSS 411

Query: 299 YGITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLM 358
            G  KD                                                    + 
Sbjct: 412 MGFGKD----------------------------------------------------VR 419

Query: 359 GIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGI 418
           G+  +P   +G ++GG I+KK K+  +++A +    S +  L +   F++ CE+ ++ GI
Sbjct: 420 GVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGI 479

Query: 419 NTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETS--IGTG 476
           N  Y   P       ++   CNV+C C    ++PVCG++G++Y + CLAGC  S  + TG
Sbjct: 480 NIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTG 539

Query: 477 INMVFQNCSCIQT------------------------SGNSSAVLGLCDKGPDCSLMLQY 512
           I   +  C+C+Q+                        + N  AV G C +   C+ ++  
Sbjct: 540 IRN-YTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKR--TCNTLIP- 595

Query: 513 FLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMD 572
           FL+   + +FI + A     +V LR ++ EE+   +G+     R  A IP PIYFGA++D
Sbjct: 596 FLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVID 655

Query: 573 STCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRGSSFV 614
           +TC+ W   +CG  G+C  Y+ T+FR++Y GL A L+   F+
Sbjct: 656 TTCMLW-QQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFI 696


>gi|39777594 solute carrier organic anion transporter family member
           4A1 [Homo sapiens]
          Length = 722

 Score =  281 bits (718), Expect = 2e-75
 Identities = 174/592 (29%), Positives = 287/592 (48%), Gaps = 38/592 (6%)

Query: 21  MFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSYFG 80
           +F L         T++G ++N+++T +ER++++ +   G I  S++I   L + FVSYFG
Sbjct: 106 LFFLCAAAFLQGMTVNG-FINTVITSLERRYDLHSYQSGLIASSYDIAACLCLTFVSYFG 164

Query: 81  TKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCMENGTQIL 140
              H+P  +G G ++MG G  + +LPHF   +YE E    V    ++   +C ++ + + 
Sbjct: 165 GSGHKPRWLGWGVLLMGTGSLVFALPHFTAGRYEVELDAGVRTCPANPGAVCADSTSGLS 224

Query: 141 RPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIGLVE 200
           R                 +  ++G  + G+G TP+  LG++Y+++  K   SP+YI +  
Sbjct: 225 R---------------YQLVFMLGQFLHGVGATPLYTLGVTYLDENVKSSCSPVYIAIFY 269

Query: 201 TGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTA 260
           T AI+GP  G L+     N+Y + G        +T     WVGAWW GFL        TA
Sbjct: 270 TAAILGPAAGYLIGGALLNIYTEMGRRTE----LTTESPLWVGAWWVGFLGSGAAAFFTA 325

Query: 261 IPFFFLPNTLP-KEGLETNADIIKNENEDKQKEEVKKEKYGITKDFLPF-MKSLSCNPIY 318
           +P    P  LP  +          ++ +D  + E     +G T   LP  +  L  NP +
Sbjct: 326 VPILGYPRQLPGSQRYAVMRAAEMHQLKDSSRGEASNPDFGKTIRDLPLSIWLLLKNPTF 385

Query: 319 MLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMK 378
           +L  L    +      M +F PK+LE Q+ +S+S+A  L G   +P    G  +GG  + 
Sbjct: 386 ILLCLAGATEATLITGMSTFSPKFLESQFSLSASEAATLFGYLVVPAGGGGTFLGGFFVN 445

Query: 379 KFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEG--IPQDLYVENDIF 436
           K ++         C    +  LL  L F + C +  + G+  SY G  +P+      ++ 
Sbjct: 446 KLRLRGSAVIKF-CLFCTVVSLLGILVFSLHCPSVPMAGVTASYGGSLLPEG---HLNLT 501

Query: 437 ADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGIN--MVFQNCSCIQ---TSG 491
           A CN  C+C  + + PVCG++GL Y S C AGC  +  T ++   V+++CSCI    +SG
Sbjct: 502 APCNAACSCQPEHYSPVCGSDGLMYFSLCHAGCPAATETNVDGQKVYRDCSCIPQNLSSG 561

Query: 492 NSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLH 551
              A  G C        +L  F+ +    +F   L++IP     LRC++  ++S  +G+ 
Sbjct: 562 FGHATAGKCTSTCQRKPLLLVFIFVVIFFTF---LSSIPALTATLRCVRDPQRSFALGIQ 618

Query: 552 TFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIY-DSTTFRYIYL 602
               R+  GIP PI FG ++D  CL W   +CG+ G+C +Y +S   RYI +
Sbjct: 619 WIVVRILGGIPGPIAFGWVIDKACLLWQD-QCGQQGSCLVYQNSAMSRYILI 669


>gi|225637477 solute carrier organic anion transporter family,
           member 5A1 isoform 2 [Homo sapiens]
          Length = 687

 Score =  259 bits (663), Expect = 4e-69
 Identities = 155/496 (31%), Positives = 263/496 (53%), Gaps = 35/496 (7%)

Query: 16  LSKLKMFLLAIT-CAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLII 74
           L+  + FL+ +    F+   +   Y++S++T IER++++ +S  G +   F+IGNL++++
Sbjct: 124 LTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVV 183

Query: 75  FVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSS-NSFLCM 133
           FVSYFG +  RP+ + +G +++  G  L +LPHF+   Y+ +       N S+ N  LC 
Sbjct: 184 FVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQEL-----NASAPNDGLCQ 238

Query: 134 ENGTQILRPTQDPSECTKEVK-SLMWVYV---LVGNIVRGMGETPILPLGISYIEDFAKF 189
              +     T +P  C K+   +  WVYV   +   I+ GMG TPI  LG +Y++D  K 
Sbjct: 239 GGNSTA---TLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKK 295

Query: 190 ENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGF 249
           ENS LY+ ++     +GP +G LL       YVD      + + +   D R++G WW GF
Sbjct: 296 ENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVDP----RNPVHLDQNDPRFIGNWWSGF 351

Query: 250 LICAGVNVLTAIPFFFLPNTLP-------KEGLETNA----DIIKNENEDKQKEEVKKEK 298
           L+CA    L   P F  P  LP       K+    +A    D++K ++ + ++ + K   
Sbjct: 352 LLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSS 411

Query: 299 YGITKDF--LPFMKSLSCNPIYMLFILVSVIQFNAFVN-MISFMPKYLEQQYGISSSDAI 355
            G  KD   LP       + +  LF+ +S    +A V   I+F+PK++E Q+GI +S+A 
Sbjct: 412 MGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNAS 471

Query: 356 FLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSV 415
              G+  +P   +G ++GG I+KK K+  +++A +    S +  L +   F++ CE+ ++
Sbjct: 472 IYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINL 531

Query: 416 VGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETS--I 473
            GIN  Y   P       ++   CNV+C C    ++PVCG++G++Y + CLAGC  S  +
Sbjct: 532 GGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNL 591

Query: 474 GTGINMVFQNCSCIQT 489
            TGI   +  C+C+Q+
Sbjct: 592 STGIRN-YTECTCVQS 606


>gi|223634014 solute carrier organic anion transporter family,
           member 2B1 isoform 3 [Homo sapiens]
          Length = 565

 Score =  253 bits (645), Expect = 5e-67
 Identities = 153/495 (30%), Positives = 254/495 (51%), Gaps = 41/495 (8%)

Query: 161 VLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANV 220
           + V   + G+G  PI P GISYI+DFA   NSPLY+G++    ++GP +   L S    +
Sbjct: 48  MFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRL 107

Query: 221 YVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLE---- 276
           YVD   +    + +T  D RWVGAWW GFLI AG   L AIP+FF P  +PKE  E    
Sbjct: 108 YVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFR 167

Query: 277 ------TNADIIKNENEDKQKE--EVKKEKYGIT------------KDFLPFMKSLSCNP 316
                 T++   K ++   ++   E  K++ G+             K F   +     +P
Sbjct: 168 RKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHP 227

Query: 317 IYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLI 376
           I++L +L  V   +    M +F+PK+LE+Q+ I++S A  L+G  + P + +G ++GG++
Sbjct: 228 IFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVL 287

Query: 377 MKKFKITVKQAAHIGCWLSLLEYLLYFLS-FLMTCENSSVVGINTSYEGIPQDLYVENDI 435
           +K+  +       + C L +L  L + L  F + C +  + GI       P       ++
Sbjct: 288 VKRLHLGPVGCGAL-CLLGMLLCLFFSLPLFFIGCSSHQIAGITHQTSAHP-----GLEL 341

Query: 436 FADCNVDCNCPSKIWDPVCG-NNGLSYLSACLAGCETSIG----TGINMVFQNCSCIQTS 490
              C   C+CP   ++PVC  +  + Y++ C AGC + +         + + NCSC+   
Sbjct: 342 SPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCV-VE 400

Query: 491 GNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGL 550
           GN   + G CD    CS ++  FL+L ++ S +  L   P +M++LR +K E+K+L VG+
Sbjct: 401 GN-PVLAGSCDS--TCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGI 457

Query: 551 HTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRG 610
                R+ A +P+P+  G+ +D+TC+HW  L CG    CR Y++   R  ++GL    + 
Sbjct: 458 QFMFLRILAWMPSPVIHGSAIDTTCVHW-ALSCGRRAVCRYYNNDLLRNRFIGLQFFFKT 516

Query: 611 SSFVPALIILILLRK 625
            S +   ++L +LR+
Sbjct: 517 GSVICFALVLAVLRQ 531



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 22/92 (23%), Positives = 41/92 (44%), Gaps = 2/92 (2%)

Query: 21  MFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLL-IIFVSYF 79
           +FLL +       +++      +   +ERQF+I  S    + G     ++++ I+     
Sbjct: 228 IFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVL 287

Query: 80  GTKLH-RPIMIGIGCVVMGLGCFLKSLPHFLM 110
             +LH  P+  G  C++  L C   SLP F +
Sbjct: 288 VKRLHLGPVGCGALCLLGMLLCLFFSLPLFFI 319


>gi|93277099 solute carrier organic anion transporter family, member
           6A1 [Homo sapiens]
          Length = 719

 Score =  191 bits (486), Expect = 1e-48
 Identities = 135/596 (22%), Positives = 261/596 (43%), Gaps = 30/596 (5%)

Query: 15  CLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLII 74
           C + ++ F++      + + +    ++  +   ++++ + T     +  S++I + L+ I
Sbjct: 101 CCNNIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAI 160

Query: 75  FVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCME 134
           F++++G +  + I       ++GLG  L + P   +N+   +S V +         +C E
Sbjct: 161 FIAFYGDR-KKVIWFVASSFLIGLGSLLCAFPS--INEENKQSKVGIED-------ICEE 210

Query: 135 NGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPL 194
                ++            +S    + ++G  V+G+   P+  LGI++I++     ++ +
Sbjct: 211 -----IKVVSGCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGI 265

Query: 195 YIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAG 254
           Y+G+ E  ++IG  +G +L +    V  +T   +  +  +      W+  WW  FL  A 
Sbjct: 266 YLGIAECTSMIGYALGYVLGAPLVKVPENT--TSATNTTVNNGSPEWLWTWWINFLFAAV 323

Query: 255 VNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYGIT-KDFLPFMKSLS 313
           V   T IP    PN +P     T     K +        +K  K G   KD    +  L 
Sbjct: 324 VAWCTLIPLSCFPNNMPGS---TRIKARKRKQLHFFDSRLKDLKLGTNIKDLCAALWILM 380

Query: 314 CNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIG 373
            NP+ +   L    ++   +    F+P YLE Q+ ++ + A  L G+  +P   +G ++G
Sbjct: 381 KNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLVLIPGGALGQLLG 440

Query: 374 GLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEGIPQDLYVEN 433
           G+I+   +++ K         S++  +L      + C      GIN  Y+G  +      
Sbjct: 441 GVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINEDYDGTGK----LG 496

Query: 434 DIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMVFQNCSCIQTSGNS 493
           ++ A CN  C C S I+  +CG + + Y S C AGC  S       ++ NCSCI+    +
Sbjct: 497 NLTAPCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKAQNQKKMYYNCSCIKEGLIT 556

Query: 494 SAVLG-LCDKGP---DCSLMLQYFLILSAMSSFIYS-LAAIPGYMVLLRCMKSEEKSLGV 548
           +   G   D  P   D         I    S+ I+S  + +P  + + R +  + +SL +
Sbjct: 557 ADAEGDFIDARPGKCDAKCYKLPLFIAFIFSTLIFSGFSGVPIVLAMTRVVPDKLRSLAL 616

Query: 549 GLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGL 604
           G+     R+F  IP P  F    +++C+     KCG +G C IY+ T   ++ +G+
Sbjct: 617 GVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIYNKTKMAFLLVGI 672


>gi|11863156 RECK protein precursor [Homo sapiens]
          Length = 971

 Score = 36.6 bits (83), Expect = 0.077
 Identities = 17/38 (44%), Positives = 23/38 (60%), Gaps = 1/38 (2%)

Query: 432 ENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGC 469
           E+D      + CNC  + + PVCG NG +Y SAC+A C
Sbjct: 622 EDDRRTFTGLPCNCADQ-FVPVCGQNGRTYPSACIARC 658


>gi|5453652 follistatin isoform FST317 precursor [Homo sapiens]
          Length = 317

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 8/66 (12%)

Query: 439 CNVDCNCPSKIWDPVCGNNGLSYLSAC-LAGCETSIGTGINMVFQ-------NCSCIQTS 490
           CN  C  P+     +CGN+G++Y SAC L      +G  I + ++       +C  IQ +
Sbjct: 192 CNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCT 251

Query: 491 GNSSAV 496
           G    +
Sbjct: 252 GGKKCL 257


>gi|7242222 follistatin isoform FST344 precursor [Homo sapiens]
          Length = 344

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 8/66 (12%)

Query: 439 CNVDCNCPSKIWDPVCGNNGLSYLSAC-LAGCETSIGTGINMVFQ-------NCSCIQTS 490
           CN  C  P+     +CGN+G++Y SAC L      +G  I + ++       +C  IQ +
Sbjct: 192 CNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCT 251

Query: 491 GNSSAV 496
           G    +
Sbjct: 252 GGKKCL 257


>gi|54873613 agrin [Homo sapiens]
          Length = 2045

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 8/77 (10%)

Query: 443 CNCP---SKIWDPVCGNNGLSYLSAC-LAGCETSIGTGINMV----FQNCSCIQTSGNSS 494
           C C    S ++DPVCG++G++Y SAC L     ++G  I +        C   +      
Sbjct: 488 CECLQACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPCDRCGQCRFGALCE 547

Query: 495 AVLGLCDKGPDCSLMLQ 511
           A  G C    +C  + Q
Sbjct: 548 AETGRCVCPSECVALAQ 564



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 3/39 (7%)

Query: 439 CNVDCNCPSKIWDPVCGNNGLSYLSAC---LAGCETSIG 474
           C  D +C S    PVCG++G++Y + C    A CE+  G
Sbjct: 703 CVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRG 741


>gi|45505132 serine protease inhibitor, Kazal type 1 precursor [Homo
           sapiens]
          Length = 79

 Score = 32.0 bits (71), Expect = 1.9
 Identities = 13/30 (43%), Positives = 20/30 (66%)

Query: 437 ADCNVDCNCPSKIWDPVCGNNGLSYLSACL 466
           A C  + N  +KI+DPVCG +G +Y + C+
Sbjct: 30  AKCYNELNGCTKIYDPVCGTDGNTYPNECV 59


>gi|12383051 transmembrane protein with EGF-like and two
           follistatin-like domains 2 [Homo sapiens]
          Length = 374

 Score = 32.0 bits (71), Expect = 1.9
 Identities = 12/32 (37%), Positives = 23/32 (71%), Gaps = 2/32 (6%)

Query: 434 DIFADCNVDCNCPSKIWDPVCGNNGLSYLSAC 465
           D++  CN+DC+  +  ++P+C ++G SY +AC
Sbjct: 177 DVWCVCNIDCSQTN--FNPLCASDGKSYDNAC 206



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 39/155 (25%), Positives = 57/155 (36%), Gaps = 43/155 (27%)

Query: 392 CWLSLLEYLLY----------FLSFLMTCENSSVVGINTS-YEGIPQDLYVEND----IF 436
           CWL LL  +L           F + L  C+  +  G N S Y+    DL++ +       
Sbjct: 20  CWLLLLPVMLLIVARPVKLAAFPTSLSDCQTPT--GWNCSGYDDRENDLFLCDTNTCKFD 77

Query: 437 ADC-----NVDCNCPSKI---WDPVCGNNGLSYLSACL-----------------AGCET 471
            +C      V C C  K    + PVCG+NG SY + C                    C T
Sbjct: 78  GECLRIGDTVTCVCQFKCNNDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCAT 137

Query: 472 SIGTGINMVFQNCSCIQTSGNSSAVLGLCDKGPDC 506
             G+G        S  +TS   ++   +C  G +C
Sbjct: 138 DAGSGSGDGVHEGSG-ETSQKETSTCDICQFGAEC 171


>gi|185134902 olfactory receptor, family 2, subfamily J, member 3
           [Homo sapiens]
          Length = 311

 Score = 32.0 bits (71), Expect = 1.9
 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 2/58 (3%)

Query: 67  IGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCF-LKSLPHFLMNQYEYESTVSVSG 123
           IGNL +II +SY  + LH P+   +  +     C+   S+P  L+N +  E T+S +G
Sbjct: 43  IGNLFIII-LSYLDSHLHTPMYFFLSNLSFLDLCYTTSSIPQLLVNLWGPEKTISYAG 99


>gi|5031701 follistatin-like 3 glycoprotein precursor [Homo sapiens]
          Length = 263

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 4/44 (9%)

Query: 426 PQDLYVENDIFADCNV----DCNCPSKIWDPVCGNNGLSYLSAC 465
           PQ   V+    A C V     C  PS     +CGNN ++Y+S+C
Sbjct: 179 PQSCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSC 222


>gi|74275344 trace amine associated receptor 2 isoform 1 [Homo
          sapiens]
          Length = 351

 Score = 31.2 bits (69), Expect = 3.2
 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 39 YMNSMLTQIERQFNIPTSLVGFINGSFEI---GNLLLIIFVSYFGTKLHRP 86
          Y N    + ER   +  ++  F+ GS  I   GNL +II +SYF  +LH P
Sbjct: 28 YGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYF-KQLHTP 77


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.141    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,618,476
Number of Sequences: 37866
Number of extensions: 1112745
Number of successful extensions: 3583
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 3449
Number of HSP's gapped (non-prelim): 54
length of query: 670
length of database: 18,247,518
effective HSP length: 109
effective length of query: 561
effective length of database: 14,120,124
effective search space: 7921389564
effective search space used: 7921389564
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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