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Search of human proteins with 239749060
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239749060 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
(336 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239754500 PREDICTED: Leucine-rich repeat-containing protein E... 691 0.0
gi|239749060 PREDICTED: Leucine-rich repeat-containing protein E... 691 0.0
gi|239743086 PREDICTED: Leucine-rich repeat-containing protein E... 691 0.0
gi|239508737 PREDICTED: Leucine-rich repeat-containing protein E... 691 0.0
gi|50593002 small nuclear ribonucleoprotein polypeptide A' [Homo... 61 1e-09
gi|55743114 leucine rich repeat containing 49 [Homo sapiens] 55 1e-07
gi|14042939 chromosome 10 open reading frame 11 [Homo sapiens] 54 2e-07
gi|239752518 PREDICTED: similar to leucine rich repeat containin... 54 2e-07
gi|53828918 Rab geranylgeranyltransferase alpha [Homo sapiens] 54 2e-07
gi|33469951 Rab geranylgeranyltransferase alpha [Homo sapiens] 54 2e-07
gi|239735605 leucine rich repeat containing 36 isoform 1 [Homo s... 54 3e-07
gi|194272228 leucine rich repeat containing 48 isoform b [Homo s... 52 6e-07
gi|194272226 leucine rich repeat containing 48 isoform b [Homo s... 52 6e-07
gi|194272224 leucine rich repeat containing 48 isoform a [Homo s... 52 6e-07
gi|194272222 leucine rich repeat containing 48 isoform a [Homo s... 52 6e-07
gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo sap... 52 6e-07
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 48 1e-05
gi|62899065 centrosomal protein 72 kDa [Homo sapiens] 47 2e-05
gi|21389483 leucine-rich repeats and guanylate kinase domain con... 47 2e-05
gi|157674358 leucine rich repeat containing 50 [Homo sapiens] 46 4e-05
gi|226342935 podocan-like 1 isoform 3 [Homo sapiens] 45 7e-05
gi|226342933 podocan-like 1 isoform 2 [Homo sapiens] 45 7e-05
gi|226342931 podocan-like 1 isoform 1 [Homo sapiens] 45 7e-05
gi|41281398 soc-2 suppressor of clear homolog [Homo sapiens] 45 7e-05
gi|61966709 leucine rich repeat containing 67 [Homo sapiens] 45 9e-05
gi|31621309 leucine rich repeat containing 6 [Homo sapiens] 45 9e-05
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 42 6e-04
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof... 42 6e-04
gi|148664213 leucine rich repeat containing 43 isoform 1 [Homo s... 41 0.001
gi|41350214 asporin [Homo sapiens] 41 0.002
>gi|239754500 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 691 bits (1782), Expect = 0.0
Identities = 336/336 (100%), Positives = 336/336 (100%)
Query: 1 MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT 60
MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT
Sbjct: 1 MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT 60
Query: 61 LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY 120
LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY
Sbjct: 61 LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY 120
Query: 121 LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK 180
LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK
Sbjct: 121 LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK 180
Query: 181 ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA 240
ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA
Sbjct: 181 ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA 240
Query: 241 HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS 300
HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS
Sbjct: 241 HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS 300
Query: 301 VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR 336
VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR
Sbjct: 301 VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR 336
>gi|239749060 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 691 bits (1782), Expect = 0.0
Identities = 336/336 (100%), Positives = 336/336 (100%)
Query: 1 MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT 60
MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT
Sbjct: 1 MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT 60
Query: 61 LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY 120
LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY
Sbjct: 61 LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY 120
Query: 121 LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK 180
LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK
Sbjct: 121 LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK 180
Query: 181 ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA 240
ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA
Sbjct: 181 ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA 240
Query: 241 HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS 300
HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS
Sbjct: 241 HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS 300
Query: 301 VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR 336
VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR
Sbjct: 301 VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR 336
>gi|239743086 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 691 bits (1782), Expect = 0.0
Identities = 336/336 (100%), Positives = 336/336 (100%)
Query: 1 MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT 60
MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT
Sbjct: 1 MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT 60
Query: 61 LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY 120
LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY
Sbjct: 61 LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY 120
Query: 121 LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK 180
LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK
Sbjct: 121 LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK 180
Query: 181 ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA 240
ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA
Sbjct: 181 ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA 240
Query: 241 HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS 300
HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS
Sbjct: 241 HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS 300
Query: 301 VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR 336
VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR
Sbjct: 301 VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR 336
>gi|239508737 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 691 bits (1782), Expect = 0.0
Identities = 336/336 (100%), Positives = 336/336 (100%)
Query: 1 MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT 60
MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT
Sbjct: 1 MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT 60
Query: 61 LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY 120
LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY
Sbjct: 61 LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY 120
Query: 121 LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK 180
LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK
Sbjct: 121 LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK 180
Query: 181 ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA 240
ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA
Sbjct: 181 ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA 240
Query: 241 HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS 300
HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS
Sbjct: 241 HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS 300
Query: 301 VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR 336
VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR
Sbjct: 301 VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR 336
>gi|50593002 small nuclear ribonucleoprotein polypeptide A' [Homo
sapiens]
Length = 255
Score = 61.2 bits (147), Expect = 1e-09
Identities = 49/139 (35%), Positives = 71/139 (51%), Gaps = 7/139 (5%)
Query: 112 LSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEI-EGLHY-LPSLHILLLHH 169
L +F + + KL G L R L L +NNN I I EGL LP L L+L +
Sbjct: 41 LDQFDAIDFSDNEIRKLDGFPLLRR---LKTLLVNNNRICRIGEGLDQALPCLTELILTN 97
Query: 170 NELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERR 229
N L + + L + +L LS+ +NP+ YRLY+IY +P V +LD +V KER+
Sbjct: 98 NSLVEL-GDLDPLASLKSLTYLSILRNPVTNKKHYRLYVIYKVPQVRVLDFQKVKLKERQ 156
Query: 230 SMITIFNHKK-AHIVQSIA 247
+F K+ A + + IA
Sbjct: 157 EAEKMFKGKRGAQLAKDIA 175
>gi|55743114 leucine rich repeat containing 49 [Homo sapiens]
Length = 686
Score = 54.7 bits (130), Expect = 1e-07
Identities = 57/241 (23%), Positives = 107/241 (44%), Gaps = 31/241 (12%)
Query: 60 TLRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLK 119
TLRC R+ + ++ ++ + + DV +L ++T++ +++ +L+
Sbjct: 154 TLRCLRVLLLGKNRIK--------KISNLENLKSLDVLDLH--GNQITKIENINHLCELR 203
Query: 120 YLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATV 179
L L N L + L LTEL L +N I + + LP L L L N +++ D+ V
Sbjct: 204 VLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDVDNLPCLQHLFLSFNNISSFDS-V 262
Query: 180 KELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIF---- 235
L +L ++ NP+ Q + Y+ ++ ++ + LD ++TE+ERR +
Sbjct: 263 SCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQLDMKRITEEERRMASVLAKKEE 322
Query: 236 -----NHKKAHIVQSIAFG-GKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPE 289
+HK++ + + V WD + QRV + A N D+ D P+
Sbjct: 323 EKKRESHKQSLLKEKKRLTINNVARQWDLQQ-------QRVAN---IATNEDRKDSDSPQ 372
Query: 290 D 290
D
Sbjct: 373 D 373
Score = 53.5 bits (127), Expect = 3e-07
Identities = 41/132 (31%), Positives = 66/132 (50%), Gaps = 6/132 (4%)
Query: 67 RRASETALQSSRRAVEDQ-LKICGHRRDADVFELF-LSKKELTEVIDLSRFKKLKYLWLH 124
R + E L S R ++E Q L +C D L +T + ++S +KL L L+
Sbjct: 83 RSSEEKILYSDRLSLERQKLTVCPIINGEDHLRLLNFQHNFITRIQNISNLQKLISLDLY 142
Query: 125 HNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVKELKG 184
N++ I+ L+ CL L L N I +I L L SL +L LH N++T I+ +
Sbjct: 143 DNQIEEISGLSTLRCLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIE----NINH 198
Query: 185 MLNLKILSLYQN 196
+ L++L+L +N
Sbjct: 199 LCELRVLNLARN 210
>gi|14042939 chromosome 10 open reading frame 11 [Homo sapiens]
Length = 198
Score = 54.3 bits (129), Expect = 2e-07
Identities = 40/130 (30%), Positives = 62/130 (47%), Gaps = 16/130 (12%)
Query: 119 KYLWL---HHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNI 175
KYL L H + + L+ L EL L+NN + + L LP LH L L+ N +T++
Sbjct: 3 KYLSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDL 62
Query: 176 DATVKELKGMLN-LKILSLYQNPLC------------QYNLYRLYIIYHLPGVELLDRNQ 222
+ + L + L+ LSL N C Y YR +++Y LP ++ LD +
Sbjct: 63 ENLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLDAQK 122
Query: 223 VTEKERRSMI 232
VT +ER +
Sbjct: 123 VTRQEREEAL 132
>gi|239752518 PREDICTED: similar to leucine rich repeat containing
50, partial [Homo sapiens]
Length = 489
Score = 53.9 bits (128), Expect = 2e-07
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 22/202 (10%)
Query: 99 LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHY 158
L L ++T++ +++ +L+ L L N L + L LTEL L +N I + +
Sbjct: 8 LDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDVDN 67
Query: 159 LPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELL 218
LP L L L N +++ D+ V L +L ++ NP+ Q + Y+ ++ ++ + L
Sbjct: 68 LPCLQHLFLSFNNISSFDS-VSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQL 126
Query: 219 DRNQVTEKERRSMITIF---------NHKKAHIVQSIAFG-GKVDASWDPKSPFKQKPAQ 268
D ++TE+ERR + +HK++ + + V WD + Q
Sbjct: 127 DMKRITEEERRMASVLAKKEEEKKRESHKQSLLKEKKRLTINNVARQWDLQ--------Q 178
Query: 269 RVPSDFAFANNVDKTVLDDPED 290
RV + A N D+ D P+D
Sbjct: 179 RVAN---IATNEDRKDSDSPQD 197
>gi|53828918 Rab geranylgeranyltransferase alpha [Homo sapiens]
Length = 567
Score = 53.9 bits (128), Expect = 2e-07
Identities = 39/108 (36%), Positives = 58/108 (53%), Gaps = 2/108 (1%)
Query: 94 ADVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGIT-FLTRNYCLTELYLNNNAIFE 152
A+V L L+ K+LT + L + + +L L HN+L + L CL L ++NAI
Sbjct: 441 AEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIES 500
Query: 153 IEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQ 200
++G+ LP L LLL +N L A ++ L L +L+L NPLCQ
Sbjct: 501 LDGVTNLPRLQELLLCNNRLQQ-PAVLQPLASCPRLVLLNLQGNPLCQ 547
>gi|33469951 Rab geranylgeranyltransferase alpha [Homo sapiens]
Length = 567
Score = 53.9 bits (128), Expect = 2e-07
Identities = 39/108 (36%), Positives = 58/108 (53%), Gaps = 2/108 (1%)
Query: 94 ADVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGIT-FLTRNYCLTELYLNNNAIFE 152
A+V L L+ K+LT + L + + +L L HN+L + L CL L ++NAI
Sbjct: 441 AEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIES 500
Query: 153 IEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQ 200
++G+ LP L LLL +N L A ++ L L +L+L NPLCQ
Sbjct: 501 LDGVTNLPRLQELLLCNNRLQQ-PAVLQPLASCPRLVLLNLQGNPLCQ 547
>gi|239735605 leucine rich repeat containing 36 isoform 1 [Homo
sapiens]
Length = 754
Score = 53.5 bits (127), Expect = 3e-07
Identities = 44/134 (32%), Positives = 68/134 (50%), Gaps = 11/134 (8%)
Query: 99 LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYC-LTELYLNNNAIFEIEGLH 157
L L + EL E + L + K+H I RN+ L L L+ N I ++G+
Sbjct: 18 LTLEQPELVESLSLQGS--------YAGKIHSIGDAFRNFKNLRSLDLSRNLITSLKGIQ 69
Query: 158 YLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNL-YRLYIIYHLPGVE 216
YL SL L L++N + ++ V L+ + LK L L NP+ + + YRL+ +Y L +E
Sbjct: 70 YLCSLQDLNLYYNNIPSL-VEVSRLQPLPFLKELDLRLNPVVRKDTDYRLFAVYTLQTLE 128
Query: 217 LLDRNQVTEKERRS 230
LD V E ER++
Sbjct: 129 KLDDRTVREGERKA 142
>gi|194272228 leucine rich repeat containing 48 isoform b [Homo
sapiens]
Length = 457
Score = 52.4 bits (124), Expect = 6e-07
Identities = 45/156 (28%), Positives = 75/156 (48%), Gaps = 21/156 (13%)
Query: 95 DVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIE 154
DV L L + + + +L +F+ L+ L L +N + I L L L L+ N I IE
Sbjct: 44 DVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIE 103
Query: 155 GLHYLPSLHILLLHHNELTNI---DATVK---------ELKGMLN---------LKILSL 193
GL L +L L L +N ++ I DA VK + M+N L+ LSL
Sbjct: 104 GLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSL 163
Query: 194 YQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERR 229
+NP+ + Y+++I +LP + LD ++ + ++
Sbjct: 164 SRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKK 199
>gi|194272226 leucine rich repeat containing 48 isoform b [Homo
sapiens]
Length = 457
Score = 52.4 bits (124), Expect = 6e-07
Identities = 45/156 (28%), Positives = 75/156 (48%), Gaps = 21/156 (13%)
Query: 95 DVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIE 154
DV L L + + + +L +F+ L+ L L +N + I L L L L+ N I IE
Sbjct: 44 DVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIE 103
Query: 155 GLHYLPSLHILLLHHNELTNI---DATVK---------ELKGMLN---------LKILSL 193
GL L +L L L +N ++ I DA VK + M+N L+ LSL
Sbjct: 104 GLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSL 163
Query: 194 YQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERR 229
+NP+ + Y+++I +LP + LD ++ + ++
Sbjct: 164 SRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKK 199
>gi|194272224 leucine rich repeat containing 48 isoform a [Homo
sapiens]
Length = 523
Score = 52.4 bits (124), Expect = 6e-07
Identities = 45/156 (28%), Positives = 75/156 (48%), Gaps = 21/156 (13%)
Query: 95 DVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIE 154
DV L L + + + +L +F+ L+ L L +N + I L L L L+ N I IE
Sbjct: 44 DVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIE 103
Query: 155 GLHYLPSLHILLLHHNELTNI---DATVK---------ELKGMLN---------LKILSL 193
GL L +L L L +N ++ I DA VK + M+N L+ LSL
Sbjct: 104 GLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSL 163
Query: 194 YQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERR 229
+NP+ + Y+++I +LP + LD ++ + ++
Sbjct: 164 SRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKK 199
>gi|194272222 leucine rich repeat containing 48 isoform a [Homo
sapiens]
Length = 523
Score = 52.4 bits (124), Expect = 6e-07
Identities = 45/156 (28%), Positives = 75/156 (48%), Gaps = 21/156 (13%)
Query: 95 DVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIE 154
DV L L + + + +L +F+ L+ L L +N + I L L L L+ N I IE
Sbjct: 44 DVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIE 103
Query: 155 GLHYLPSLHILLLHHNELTNI---DATVK---------ELKGMLN---------LKILSL 193
GL L +L L L +N ++ I DA VK + M+N L+ LSL
Sbjct: 104 GLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSL 163
Query: 194 YQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERR 229
+NP+ + Y+++I +LP + LD ++ + ++
Sbjct: 164 SRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKK 199
>gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo
sapiens]
Length = 360
Score = 52.4 bits (124), Expect = 6e-07
Identities = 42/142 (29%), Positives = 65/142 (45%), Gaps = 21/142 (14%)
Query: 99 LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHY 158
LFL K ++T++ +L L L + N+L I L L ELYL++N I IEGL
Sbjct: 213 LFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLEN 272
Query: 159 LPSLHILLLHHNELTNID---------------------ATVKELKGMLNLKILSLYQNP 197
L +L + N + I+ + + ELKG +L+ + L +NP
Sbjct: 273 NNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNP 332
Query: 198 LCQYNLYRLYIIYHLPGVELLD 219
L + YR ++ LP V +D
Sbjct: 333 LQKDPQYRRKVMLALPSVRQID 354
Score = 46.2 bits (108), Expect = 4e-05
Identities = 37/128 (28%), Positives = 65/128 (50%), Gaps = 13/128 (10%)
Query: 99 LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHY 158
L +S L + + + +LK L+L +NK+ I L+ + L L L +N I IE +
Sbjct: 147 LDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDT 206
Query: 159 LPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQ-------YNLYRLYIIYH 211
L +L L L N++T + + L + NL +LS+ N L + NL LY+ ++
Sbjct: 207 LTNLESLFLGKNKITKL----QNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHN 262
Query: 212 LPGVELLD 219
G+E+++
Sbjct: 263 --GIEVIE 268
Score = 41.2 bits (95), Expect = 0.001
Identities = 37/121 (30%), Positives = 56/121 (46%), Gaps = 8/121 (6%)
Query: 93 DADVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFE 152
D D ++ L+ + ++ KK+K L L N + I L L EL L +N I +
Sbjct: 75 DRDAEDVDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKK 134
Query: 153 IEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQY----NLYRLYI 208
IE L L L IL + N L NI+ K + LK L L N + + NL++L +
Sbjct: 135 IENLEALTELEILDISFNLLRNIEGVDK----LTRLKKLFLVNNKISKIENLSNLHQLQM 190
Query: 209 I 209
+
Sbjct: 191 L 191
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 48.1 bits (113), Expect = 1e-05
Identities = 49/164 (29%), Positives = 77/164 (46%), Gaps = 26/164 (15%)
Query: 99 LFLSK---KELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEG 155
L LSK K+ + +L + KL+ L L +N + I L + L EL L+ N I +IEG
Sbjct: 105 LSLSKDGGKKFKYIENLEKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNKISKIEG 164
Query: 156 LHYLPSLHILLLHHNELTNIDATV-KELKGM--LNLK--------------------ILS 192
+ + +L L L NE+ +I + K+LK + LNLK L
Sbjct: 165 IENMCNLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLKGNKISSLQDISKLKPLQDLISLI 224
Query: 193 LYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFN 236
L +NP+ Y + I+HL +E L+ VT ++R+ F+
Sbjct: 225 LVENPVVTLPHYLQFTIFHLRSLESLEGQPVTTQDRQEAFERFS 268
>gi|62899065 centrosomal protein 72 kDa [Homo sapiens]
Length = 647
Score = 47.4 bits (111), Expect = 2e-05
Identities = 35/125 (28%), Positives = 64/125 (51%), Gaps = 9/125 (7%)
Query: 111 DLSRFKKLKYLWLHHNKL----HGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILL 166
DL+ + L + K+ H + LT L L L+ N++ +EG+ YL +L L
Sbjct: 26 DLAELQSLSIPGTYQEKITHLGHSLMSLTG---LKSLDLSRNSLVSLEGIQYLTALESLN 82
Query: 167 LHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNL-YRLYIIYHLPGVELLDRNQVTE 225
L++N ++++ A V L + L + NP+ + YRL++++ LP ++ LD V
Sbjct: 83 LYYNCISSL-AEVFRLHALTELVDVDFRLNPVVKVEPDYRLFVVHLLPKLQQLDDRPVRA 141
Query: 226 KERRS 230
ER++
Sbjct: 142 SERKA 146
>gi|21389483 leucine-rich repeats and guanylate kinase domain
containing [Homo sapiens]
Length = 825
Score = 47.0 bits (110), Expect = 2e-05
Identities = 44/178 (24%), Positives = 80/178 (44%), Gaps = 44/178 (24%)
Query: 102 SKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPS 161
S +++E+ DLS + L L L N++ I+ L L L L NN I I GL+ LP
Sbjct: 201 SHNQISEICDLSAYHALTKLILDGNEIEEISGLEMCNNLIHLSLANNKITTINGLNKLP- 259
Query: 162 LHILLLHHNE------------LTNIDAT---VKELKGMLN------------------- 187
+ IL L +N+ L N+D + + L+G+ N
Sbjct: 260 IKILCLSNNQIEMITGLEDLKALQNLDLSHNQISSLQGLENHDLLEVINLEDNKIAELRE 319
Query: 188 ---------LKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFN 236
L++L+L +NP+ + + Y ++I+ L + LD+ ++ +E+ S + ++
Sbjct: 320 IEYIKNLPILRVLNLLENPIQEKSEYWFFVIFMLLRLTELDQKKIKVEEKVSAVNKYD 377
>gi|157674358 leucine rich repeat containing 50 [Homo sapiens]
Length = 725
Score = 46.2 bits (108), Expect = 4e-05
Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 3/121 (2%)
Query: 99 LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHY 158
L+L + ++ +L +L+ L+L N L I L L L L+NN I IE L
Sbjct: 134 LWLQSNGIQKIENLEAQTELRCLFLQMNLLRKIENLEPLQKLDALNLSNNYIKTIENLSC 193
Query: 159 LPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELL 218
LP L+ L + HN L ++ ++ L+ L L +L L N L + L I+ +P + +L
Sbjct: 194 LPVLNTLQMAHNHLETVE-DIQHLQECLRLCVLDLSHNKLSDPEI--LSILESMPDLRVL 250
Query: 219 D 219
+
Sbjct: 251 N 251
>gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]
Length = 421
Score = 45.4 bits (106), Expect = 7e-05
Identities = 39/114 (34%), Positives = 56/114 (49%), Gaps = 9/114 (7%)
Query: 92 RDADVFELFLSKKELTEV-IDLSRFKKL---KYLWLHHNKLHGITF-LTRNYCLTELYLN 146
R + EL+L +LT+ +D + F KL +YL L HN+L + L R + L+L
Sbjct: 147 RQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAI--LHLG 204
Query: 147 NNAIFEIEG--LHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPL 198
N I ++E LH L LLL HN+L + L+ + L L LY N L
Sbjct: 205 RNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGL 258
>gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]
Length = 510
Score = 45.4 bits (106), Expect = 7e-05
Identities = 39/114 (34%), Positives = 56/114 (49%), Gaps = 9/114 (7%)
Query: 92 RDADVFELFLSKKELTEV-IDLSRFKKL---KYLWLHHNKLHGITF-LTRNYCLTELYLN 146
R + EL+L +LT+ +D + F KL +YL L HN+L + L R + L+L
Sbjct: 236 RQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAI--LHLG 293
Query: 147 NNAIFEIEG--LHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPL 198
N I ++E LH L LLL HN+L + L+ + L L LY N L
Sbjct: 294 RNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGL 347
Score = 33.5 bits (75), Expect = 0.28
Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
Query: 117 KLKYLWLHHNKLH-GITFLTRNYCLTELYLNNNAIFEIEGLHY--LPSLHILLLHHNELT 173
+L++L + HNKL FL R+ + +L N + EI L + P+L + LH+N+L+
Sbjct: 123 QLQHLCVAHNKLSVAPQFLPRSLRVADLAANQ--VMEIFPLTFGEKPALRSVYLHNNQLS 180
Query: 174 NIDATVKELKGMLNLKILSLYQNPL 198
N +G + LSL N L
Sbjct: 181 NAGLPPDAFRGSEAIATLSLSNNQL 205
>gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]
Length = 512
Score = 45.4 bits (106), Expect = 7e-05
Identities = 39/114 (34%), Positives = 56/114 (49%), Gaps = 9/114 (7%)
Query: 92 RDADVFELFLSKKELTEV-IDLSRFKKL---KYLWLHHNKLHGITF-LTRNYCLTELYLN 146
R + EL+L +LT+ +D + F KL +YL L HN+L + L R + L+L
Sbjct: 238 RQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAI--LHLG 295
Query: 147 NNAIFEIEG--LHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPL 198
N I ++E LH L LLL HN+L + L+ + L L LY N L
Sbjct: 296 RNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGL 349
Score = 33.5 bits (75), Expect = 0.28
Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
Query: 117 KLKYLWLHHNKLH-GITFLTRNYCLTELYLNNNAIFEIEGLHY--LPSLHILLLHHNELT 173
+L++L + HNKL FL R+ + +L N + EI L + P+L + LH+N+L+
Sbjct: 125 QLQHLCVAHNKLSVAPQFLPRSLRVADLAANQ--VMEIFPLTFGEKPALRSVYLHNNQLS 182
Query: 174 NIDATVKELKGMLNLKILSLYQNPL 198
N +G + LSL N L
Sbjct: 183 NAGLPPDAFRGSEAIATLSLSNNQL 207
>gi|41281398 soc-2 suppressor of clear homolog [Homo sapiens]
Length = 582
Score = 45.4 bits (106), Expect = 7e-05
Identities = 34/99 (34%), Positives = 52/99 (52%), Gaps = 3/99 (3%)
Query: 95 DVFELFLSKKELTEVID-LSRFKKLKYLWLHHNKLHGI-TFLTRNYCLTELYLNNNAIFE 152
++ L LS+ LT + D L KKL+ L L HNKL I + + R LT LYL N I
Sbjct: 147 NLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITT 206
Query: 153 IE-GLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKI 190
+E + L L +L + N++ + A + EL ++ L +
Sbjct: 207 VEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDV 245
>gi|61966709 leucine rich repeat containing 67 [Homo sapiens]
Length = 228
Score = 45.1 bits (105), Expect = 9e-05
Identities = 34/90 (37%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
Query: 102 SKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPS 161
S K + + DLS K L L+L+ N + IT L LT LYL NN I IE L L
Sbjct: 36 SDKNIDAIEDLSLCKNLSVLYLYDNCISQITNLNYATNLTHLYLQNNCISCIENLRSLKK 95
Query: 162 LHILLLHHNELTNIDATVKELKGMLNLKIL 191
L L L N + A ++ L+G+ L+ L
Sbjct: 96 LEKLYLGGNYI----AVIEGLEGLGELREL 121
Score = 33.1 bits (74), Expect = 0.36
Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 6/93 (6%)
Query: 80 AVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYC 139
A+ED L +C ++ L+L ++++ +L+ L +L+L +N + I L
Sbjct: 42 AIED-LSLC-----KNLSVLYLYDNCISQITNLNYATNLTHLYLQNNCISCIENLRSLKK 95
Query: 140 LTELYLNNNAIFEIEGLHYLPSLHILLLHHNEL 172
L +LYL N I IEGL L L L + + L
Sbjct: 96 LEKLYLGGNYIAVIEGLEGLGELRELHVENQRL 128
Score = 32.0 bits (71), Expect = 0.80
Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 12/77 (15%)
Query: 134 LTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSL 193
L ++ C+ L ++NN I +I L L +L+ L+ N+L + VK+L+ +LN K++ L
Sbjct: 144 LAKSLCI--LNISNNNIDDITDLELLENLNQLIAVDNQLLH----VKDLEFLLN-KLMKL 196
Query: 194 YQ-----NPLCQYNLYR 205
++ NP+C YR
Sbjct: 197 WKIDLNGNPVCLKPKYR 213
Score = 28.5 bits (62), Expect = 8.9
Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 1/73 (1%)
Query: 116 KKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNI 175
KK+ ++ + I L+ L+ LYL +N I +I L+Y +L L L +N ++ I
Sbjct: 28 KKITHINFSDKNIDAIEDLSLCKNLSVLYLYDNCISQITNLNYATNLTHLYLQNNCISCI 87
Query: 176 DATVKELKGMLNL 188
+ ++ LK + L
Sbjct: 88 E-NLRSLKKLEKL 99
>gi|31621309 leucine rich repeat containing 6 [Homo sapiens]
Length = 466
Score = 45.1 bits (105), Expect = 9e-05
Identities = 37/135 (27%), Positives = 63/135 (46%), Gaps = 25/135 (18%)
Query: 95 DVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNN-NAIFEI 153
D+ L+L + ++ ++S+ KKL+YL L LNN I +
Sbjct: 45 DLKILYLQNNLIGKIENVSKLKKLEYL--------------------NLALNNIEKIENL 84
Query: 154 EGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLP 213
EG L L + + EL++I K L+ ++LK L L NP ++ YR +++ LP
Sbjct: 85 EGCEELAKLDLTVNFIGELSSI----KNLQHNIHLKELFLMGNPCASFDHYREFVVATLP 140
Query: 214 GVELLDRNQVTEKER 228
++ LD ++ ER
Sbjct: 141 QLKWLDGKEIEPSER 155
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform 1
[Homo sapiens]
Length = 1722
Score = 42.4 bits (98), Expect = 6e-04
Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 2/125 (1%)
Query: 99 LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYC--LTELYLNNNAIFEIEGL 156
L L L+E+ L L+ L L N + + + + L + ++ N++ +I L
Sbjct: 1018 LKLQGNYLSELPSLENLVLLRELHLDDNSISTVEAFSSYWLPLLQNITISQNSLTKIVPL 1077
Query: 157 HYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVE 216
+ SL L + HN L+++ + +K +L LSL NPL Q +R ++ LP +
Sbjct: 1078 FHFVSLEKLDVSHNCLSDLKSAIKWFDACYSLHELSLTGNPLLQETNWRDSLLKVLPALR 1137
Query: 217 LLDRN 221
+L+ N
Sbjct: 1138 ILNGN 1142
Score = 35.4 bits (80), Expect = 0.073
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 99 LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLT-RNYCLTELYLNNNAIFEIEGLH 157
L L + LT + LS KKLKY+ N + I N C+ + LN N + + GL
Sbjct: 823 LSLRRCGLTSLHSLSNCKKLKYIDAQENHIEAIECENLENLCV--VLLNKNQLTSLHGLD 880
Query: 158 YLPSLHILLLHHNELTNI 175
++ L L +N++T I
Sbjct: 881 GCTNIQCLELSYNKITRI 898
>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform 2
[Homo sapiens]
Length = 1336
Score = 42.4 bits (98), Expect = 6e-04
Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 2/125 (1%)
Query: 99 LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYC--LTELYLNNNAIFEIEGL 156
L L L+E+ L L+ L L N + + + + L + ++ N++ +I L
Sbjct: 1018 LKLQGNYLSELPSLENLVLLRELHLDDNSISTVEAFSSYWLPLLQNITISQNSLTKIVPL 1077
Query: 157 HYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVE 216
+ SL L + HN L+++ + +K +L LSL NPL Q +R ++ LP +
Sbjct: 1078 FHFVSLEKLDVSHNCLSDLKSAIKWFDACYSLHELSLTGNPLLQETNWRDSLLKVLPALR 1137
Query: 217 LLDRN 221
+L+ N
Sbjct: 1138 ILNGN 1142
Score = 35.4 bits (80), Expect = 0.073
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 99 LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLT-RNYCLTELYLNNNAIFEIEGLH 157
L L + LT + LS KKLKY+ N + I N C+ + LN N + + GL
Sbjct: 823 LSLRRCGLTSLHSLSNCKKLKYIDAQENHIEAIECENLENLCV--VLLNKNQLTSLHGLD 880
Query: 158 YLPSLHILLLHHNELTNI 175
++ L L +N++T I
Sbjct: 881 GCTNIQCLELSYNKITRI 898
>gi|148664213 leucine rich repeat containing 43 isoform 1 [Homo
sapiens]
Length = 656
Score = 41.2 bits (95), Expect = 0.001
Identities = 41/138 (29%), Positives = 67/138 (48%), Gaps = 7/138 (5%)
Query: 98 ELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRN--YCLTELYLNNNAIF-EIE 154
EL LS + EV + LK L L+ N++ + L + L L L +N + +E
Sbjct: 153 ELVLSANRIKEVDATNLPPTLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKLLGPLE 212
Query: 155 GLH----YLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIY 210
L+ + P+L L L N+LT++ + V L+ + +L++L L NPL YR I
Sbjct: 213 SLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALVPYYRGLTID 272
Query: 211 HLPGVELLDRNQVTEKER 228
L + +LD V+ E+
Sbjct: 273 SLAQLCVLDDITVSPNEK 290
Score = 33.5 bits (75), Expect = 0.28
Identities = 50/202 (24%), Positives = 83/202 (41%), Gaps = 17/202 (8%)
Query: 46 PCVLMSWDPNP-VPRTLRCWR-LRRASETALQSSRRAVEDQLKICGHRRDA--------- 94
PC SW+ + +P+T R WR L E + VE L + R
Sbjct: 44 PCGAGSWNKSRFLPQTWRTWRELVPREEDVVSPGEETVEALLGLVRSRHSPWALLNNSNA 103
Query: 95 -DVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITF-LTRNYCLTELYLNNNAIFE 152
D F L+ + + D + + L + K+ + L + L EL L+ N I E
Sbjct: 104 EDSFLRELAIRNPLTITDTFFYSYFRSLRVIDKKVTLVDKDLLKFLKLEELVLSANRIKE 163
Query: 153 IEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYI-IYH 211
++ + P+L +L L+ NE+++++ L+ L L N L L LY+ H
Sbjct: 164 VDATNLPPTLKVLELYGNEISSMECLCAHPPA--GLQHLGLGHNKLLG-PLESLYVTANH 220
Query: 212 LPGVELLDRNQVTEKERRSMIT 233
P + LD + +SM+T
Sbjct: 221 WPNLVSLDLGFNDLTDLQSMVT 242
>gi|41350214 asporin [Homo sapiens]
Length = 380
Score = 40.8 bits (94), Expect = 0.002
Identities = 33/105 (31%), Positives = 53/105 (50%), Gaps = 9/105 (8%)
Query: 102 SKKELTEVIDLSRFKKLKYLWLHHNKLHGIT--FLTRNYCLTELYLNNNAIFEI-EGLHY 158
+K E+ D R+K+L+ L L +NK+ I L + E++L NN + +I GL
Sbjct: 251 NKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSGLPE 310
Query: 159 LPSLHILLLHHNELTNIDA-----TVKELKGMLNLKILSLYQNPL 198
L L I+ LH N + + TV ++K L +SL+ NP+
Sbjct: 311 LKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSL-YSAISLFNNPV 354
Score = 31.2 bits (69), Expect = 1.4
Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 5/83 (6%)
Query: 96 VFELFLSKKELTEVIDLSRF--KKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEI 153
++ L L+ +LT++ + KKL+ L+L HN+L I L L EL ++ N + +I
Sbjct: 128 LYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIP-LNLPKSLAELRIHENKVKKI 186
Query: 154 EGLHY--LPSLHILLLHHNELTN 174
+ + + +LH+L + N L N
Sbjct: 187 QKDTFKGMNALHVLEMSANPLDN 209
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.136 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,667,809
Number of Sequences: 37866
Number of extensions: 542081
Number of successful extensions: 1429
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 76
Number of HSP's that attempted gapping in prelim test: 1266
Number of HSP's gapped (non-prelim): 183
length of query: 336
length of database: 18,247,518
effective HSP length: 103
effective length of query: 233
effective length of database: 14,347,320
effective search space: 3342925560
effective search space used: 3342925560
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.