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Search of human proteins with 239747318
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239747318 PREDICTED: similar to protein phosphatase 2,
catalytic subunit, alpha [Homo sapiens]
(254 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239747318 PREDICTED: similar to protein phosphatase 2, cataly... 537 e-153
gi|239741140 PREDICTED: similar to protein phosphatase 2, cataly... 537 e-153
gi|239752750 PREDICTED: similar to protein phosphatase 2, cataly... 518 e-147
gi|4506017 protein phosphatase 2, catalytic subunit, alpha isofo... 274 6e-74
gi|57222565 protein phosphatase 2, catalytic subunit, beta isofo... 271 4e-73
gi|4758952 protein phosphatase 2, catalytic subunit, beta isofor... 271 4e-73
gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens] 205 4e-53
gi|183603931 protein phosphatase 6, catalytic subunit isoform c ... 194 6e-50
gi|4506029 protein phosphatase 6, catalytic subunit isoform b [H... 181 4e-46
gi|183603929 protein phosphatase 6, catalytic subunit isoform a ... 181 7e-46
gi|56790945 protein phosphatase 1, catalytic subunit, alpha isof... 122 2e-28
gi|4506007 protein phosphatase 1, catalytic subunit, gamma isofo... 121 5e-28
gi|4506003 protein phosphatase 1, catalytic subunit, alpha isofo... 121 5e-28
gi|46249376 protein phosphatase 1, catalytic subunit, beta isofo... 118 4e-27
gi|4506005 protein phosphatase 1, catalytic subunit, beta isofor... 118 4e-27
gi|45827798 protein phosphatase 1, catalytic subunit, alpha isof... 108 3e-24
gi|194688149 protein phosphatase 3, catalytic subunit, alpha iso... 107 8e-24
gi|194688147 protein phosphatase 3, catalytic subunit, alpha iso... 107 8e-24
gi|6715568 protein phosphatase 3, catalytic subunit, alpha isofo... 107 8e-24
gi|215272354 protein phosphatase 3, catalytic subunit, beta isof... 102 4e-22
gi|215272352 protein phosphatase 3, catalytic subunit, beta isof... 102 4e-22
gi|11036640 protein phosphatase 3, catalytic subunit, beta isofo... 102 4e-22
gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Hom... 98 6e-21
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 86 4e-17
gi|23312374 protein phosphatase with EF hand calcium-binding dom... 55 8e-08
gi|23312378 protein phosphatase with EF hand calcium-binding dom... 50 2e-06
gi|23312380 protein phosphatase with EF hand calcium-binding dom... 48 9e-06
gi|23312386 serine/threonine protein phosphatase with EF-hand mo... 44 2e-04
gi|239756297 PREDICTED: hypothetical protein [Homo sapiens] 30 1.6
gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo ... 30 1.6
>gi|239747318 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 254
Score = 537 bits (1383), Expect = e-153
Identities = 254/254 (100%), Positives = 254/254 (100%)
Query: 1 MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC 60
MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC
Sbjct: 1 MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC 60
Query: 61 KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL 120
KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL
Sbjct: 61 KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL 120
Query: 121 PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH 180
PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH
Sbjct: 121 PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH 180
Query: 181 EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY 240
EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY
Sbjct: 181 EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY 240
Query: 241 HCGVPLLLFSLLLQ 254
HCGVPLLLFSLLLQ
Sbjct: 241 HCGVPLLLFSLLLQ 254
>gi|239741140 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 254
Score = 537 bits (1383), Expect = e-153
Identities = 254/254 (100%), Positives = 254/254 (100%)
Query: 1 MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC 60
MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC
Sbjct: 1 MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC 60
Query: 61 KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL 120
KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL
Sbjct: 61 KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL 120
Query: 121 PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH 180
PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH
Sbjct: 121 PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH 180
Query: 181 EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY 240
EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY
Sbjct: 181 EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY 240
Query: 241 HCGVPLLLFSLLLQ 254
HCGVPLLLFSLLLQ
Sbjct: 241 HCGVPLLLFSLLLQ 254
>gi|239752750 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 384
Score = 518 bits (1333), Expect = e-147
Identities = 243/243 (100%), Positives = 243/243 (100%)
Query: 1 MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC 60
MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC
Sbjct: 122 MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC 181
Query: 61 KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL 120
KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL
Sbjct: 182 KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL 241
Query: 121 PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH 180
PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH
Sbjct: 242 PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH 301
Query: 181 EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY 240
EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY
Sbjct: 302 EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY 361
Query: 241 HCG 243
HCG
Sbjct: 362 HCG 364
>gi|4506017 protein phosphatase 2, catalytic subunit, alpha isoform
[Homo sapiens]
Length = 309
Score = 274 bits (700), Expect = 6e-74
Identities = 144/248 (58%), Positives = 163/248 (65%), Gaps = 55/248 (22%)
Query: 51 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 89
L +VKSLC++AKEILT+ESN QEV CPVTV GD HGQ
Sbjct: 23 LSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLF 82
Query: 90 -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNAN- 147
GDY+DRGYYS+E V LL+A+KV Y E +TIL NHESRQITQVY Y+ECLRK+GNAN
Sbjct: 83 MGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANV 142
Query: 148 ----------------GDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSD 191
DGQ+FCLHGGLSPS+DTL HIR L+ LQ++PHEGPM DLL+SD
Sbjct: 143 WKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSD 202
Query: 192 PDD----------------HDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 235
PDD D ETFNHA+GL LVSRAHQLVM G+NWCHD NVV IFS
Sbjct: 203 PDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSA 262
Query: 236 PNYCYHCG 243
PNYCY CG
Sbjct: 263 PNYCYRCG 270
>gi|57222565 protein phosphatase 2, catalytic subunit, beta isoform
[Homo sapiens]
Length = 309
Score = 271 bits (693), Expect = 4e-73
Identities = 142/248 (57%), Positives = 163/248 (65%), Gaps = 55/248 (22%)
Query: 51 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 89
L +V++LC++AKEILT+ESN QEV CPVTV GD HGQ
Sbjct: 23 LNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLF 82
Query: 90 -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNAN- 147
GDY+DRGYYS+E V LL+A+KV Y E +TIL NHESRQITQVY Y+ECLRK+GNAN
Sbjct: 83 MGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANV 142
Query: 148 ----------------GDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSD 191
DGQ+FCLHGGLSPS+DTL HIR L+ LQ++PHEGPM DLL+SD
Sbjct: 143 WKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSD 202
Query: 192 PDD----------------HDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 235
PDD D ETFNHA+GL LVSRAHQLVM G+NWCHD NVV IFS
Sbjct: 203 PDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSA 262
Query: 236 PNYCYHCG 243
PNYCY CG
Sbjct: 263 PNYCYRCG 270
>gi|4758952 protein phosphatase 2, catalytic subunit, beta isoform
[Homo sapiens]
Length = 309
Score = 271 bits (693), Expect = 4e-73
Identities = 142/248 (57%), Positives = 163/248 (65%), Gaps = 55/248 (22%)
Query: 51 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 89
L +V++LC++AKEILT+ESN QEV CPVTV GD HGQ
Sbjct: 23 LNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLF 82
Query: 90 -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNAN- 147
GDY+DRGYYS+E V LL+A+KV Y E +TIL NHESRQITQVY Y+ECLRK+GNAN
Sbjct: 83 MGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANV 142
Query: 148 ----------------GDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSD 191
DGQ+FCLHGGLSPS+DTL HIR L+ LQ++PHEGPM DLL+SD
Sbjct: 143 WKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSD 202
Query: 192 PDD----------------HDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 235
PDD D ETFNHA+GL LVSRAHQLVM G+NWCHD NVV IFS
Sbjct: 203 PDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSA 262
Query: 236 PNYCYHCG 243
PNYCY CG
Sbjct: 263 PNYCYRCG 270
>gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens]
Length = 307
Score = 205 bits (521), Expect = 4e-53
Identities = 109/244 (44%), Positives = 146/244 (59%), Gaps = 55/244 (22%)
Query: 55 KVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDY 92
+VK+LC +A+EIL EESN Q V PVTV GD HGQ GD+
Sbjct: 24 EVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDF 83
Query: 93 IDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG-------- 144
+DRG+YS+E +LLLA+KV Y + +T++ NHESRQITQVY Y+ECLRK+G
Sbjct: 84 VDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYC 143
Query: 145 ---------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDD- 194
+A DG++FC+HGGLSPS+ TL IRT++ Q++PH+GPM DLL+SDP+D
Sbjct: 144 TEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDT 203
Query: 195 ---------------HDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYC 239
D FN A+ + ++ RAHQLVM G+ W + V+ ++S PNYC
Sbjct: 204 TGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYC 263
Query: 240 YHCG 243
Y CG
Sbjct: 264 YRCG 267
>gi|183603931 protein phosphatase 6, catalytic subunit isoform c
[Homo sapiens]
Length = 283
Score = 194 bits (493), Expect = 6e-50
Identities = 102/226 (45%), Positives = 132/226 (58%), Gaps = 33/226 (14%)
Query: 51 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVK 110
L +K LC ++L EESN Q V PVTV GD HGQGD++DRGYYS+E LLA+K
Sbjct: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQGDFVDRGYYSLETFTYLLALK 78
Query: 111 VSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANG-----------------DGQLF 153
+ + +T+L NHESRQITQVY Y+EC K+GNAN D Q+
Sbjct: 79 AKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQIL 138
Query: 154 CLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDDHDT---------------- 197
C+HGGLSP + TL IRT+ Q+IPH+G DL++SDP+D DT
Sbjct: 139 CVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKV 198
Query: 198 PETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCYHCG 243
F H + L+L+ RAHQLV G+ + D +V ++S PNYCY CG
Sbjct: 199 TNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCG 244
>gi|4506029 protein phosphatase 6, catalytic subunit isoform b [Homo
sapiens]
Length = 305
Score = 181 bits (460), Expect = 4e-46
Identities = 102/248 (41%), Positives = 132/248 (53%), Gaps = 55/248 (22%)
Query: 51 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 89
L +K LC ++L EESN Q V PVTV GD HGQ
Sbjct: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIF 78
Query: 90 -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANG 148
GD++DRGYYS+E LLA+K + + +T+L NHESRQITQVY Y+EC K+GNAN
Sbjct: 79 MGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 138
Query: 149 -----------------DGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSD 191
D Q+ C+HGGLSP + TL IRT+ Q+IPH+G DL++SD
Sbjct: 139 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 198
Query: 192 PDDHDT----------------PETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 235
P+D DT F H + L+L+ RAHQLV G+ + D +V ++S
Sbjct: 199 PEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSA 258
Query: 236 PNYCYHCG 243
PNYCY CG
Sbjct: 259 PNYCYRCG 266
>gi|183603929 protein phosphatase 6, catalytic subunit isoform a
[Homo sapiens]
Length = 342
Score = 181 bits (458), Expect = 7e-46
Identities = 108/270 (40%), Positives = 138/270 (51%), Gaps = 59/270 (21%)
Query: 29 GVGSSSASLLPTPAPKAAALDGLGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHG 88
G + L P P P L L R LC ++L EESN Q V PVTV GD HG
Sbjct: 38 GAPAGRPFLSPGPPPVFHFLRFLKER----LCDYVCDLLLEESNVQPVSTPVTVCGDIHG 93
Query: 89 Q----------------------GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHES 126
Q GD++DRGYYS+E LLA+K + + +T+L NHES
Sbjct: 94 QFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHES 153
Query: 127 RQITQVYHSYEECLRKHGNANG-----------------DGQLFCLHGGLSPSVDTLHHI 169
RQITQVY Y+EC K+GNAN D Q+ C+HGGLSP + TL I
Sbjct: 154 RQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQI 213
Query: 170 RTLNCLQKIPHEGPMGDLLYSDPDDHDT----------------PETFNHASGLRLVSRA 213
RT+ Q+IPH+G DL++SDP+D DT F H + L+L+ RA
Sbjct: 214 RTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRA 273
Query: 214 HQLVMVGHNWCHDWNVVAIFSTPNYCYHCG 243
HQLV G+ + D +V ++S PNYCY CG
Sbjct: 274 HQLVHEGYKFMFDEKLVTVWSAPNYCYRCG 303
>gi|56790945 protein phosphatase 1, catalytic subunit, alpha isoform
3 [Homo sapiens]
Length = 341
Score = 122 bits (307), Expect = 2e-28
Identities = 83/265 (31%), Positives = 120/265 (45%), Gaps = 59/265 (22%)
Query: 34 SASLLPTPAPKAAALDG----LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ 89
S L P AP + G L +++ LC +++EI + E+ P+ + GD HGQ
Sbjct: 20 SRVLTPHCAPVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQ 79
Query: 90 ----------------------GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESR 127
GDY+DRG S+E + LLLA K+ Y E +L NHE
Sbjct: 80 YYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECA 139
Query: 128 QITQVYHSYEECLRKHG----------------NANGDGQLFCLHGGLSPSVDTLHHIRT 171
I ++Y Y+EC R++ A D ++FC HGGLSP + ++ IR
Sbjct: 140 SINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRR 199
Query: 172 LNCLQKIPHEGPMGDLLYSDPD---------DHDTPETFN--------HASGLRLVSRAH 214
+ +P +G + DLL+SDPD D TF H L L+ RAH
Sbjct: 200 IMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAH 259
Query: 215 QLVMVGHNWCHDWNVVAIFSTPNYC 239
Q+V G+ + +V +FS PNYC
Sbjct: 260 QVVEDGYEFFAKRQLVTLFSAPNYC 284
>gi|4506007 protein phosphatase 1, catalytic subunit, gamma isoform
[Homo sapiens]
Length = 323
Score = 121 bits (304), Expect = 5e-28
Identities = 77/244 (31%), Positives = 113/244 (46%), Gaps = 55/244 (22%)
Query: 51 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 89
L +++ LC +++EI + E+ P+ + GD HGQ
Sbjct: 30 LQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89
Query: 90 -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG---- 144
GDY+DRG S+E + LLLA K+ Y E +L NHE I ++Y Y+EC R++
Sbjct: 90 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLW 149
Query: 145 ------------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP 192
A D ++FC HGGLSP + ++ IR + +P +G + DLL+SDP
Sbjct: 150 KTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDP 209
Query: 193 D---------DHDTPETFN--------HASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 235
D D TF H L L+ RAHQ+V G+ + +V +FS
Sbjct: 210 DKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSA 269
Query: 236 PNYC 239
PNYC
Sbjct: 270 PNYC 273
>gi|4506003 protein phosphatase 1, catalytic subunit, alpha isoform
1 [Homo sapiens]
Length = 330
Score = 121 bits (304), Expect = 5e-28
Identities = 77/244 (31%), Positives = 113/244 (46%), Gaps = 55/244 (22%)
Query: 51 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 89
L +++ LC +++EI + E+ P+ + GD HGQ
Sbjct: 30 LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89
Query: 90 -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG---- 144
GDY+DRG S+E + LLLA K+ Y E +L NHE I ++Y Y+EC R++
Sbjct: 90 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLW 149
Query: 145 ------------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP 192
A D ++FC HGGLSP + ++ IR + +P +G + DLL+SDP
Sbjct: 150 KTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDP 209
Query: 193 D---------DHDTPETFN--------HASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 235
D D TF H L L+ RAHQ+V G+ + +V +FS
Sbjct: 210 DKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSA 269
Query: 236 PNYC 239
PNYC
Sbjct: 270 PNYC 273
>gi|46249376 protein phosphatase 1, catalytic subunit, beta isoform
1 [Homo sapiens]
Length = 327
Score = 118 bits (296), Expect = 4e-27
Identities = 80/269 (29%), Positives = 117/269 (43%), Gaps = 55/269 (20%)
Query: 26 GSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGD 85
G V S LL + + + +V+ LC +++EI + E+ P+ + GD
Sbjct: 4 GELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGD 63
Query: 86 KHGQ----------------------GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRN 123
HGQ GDY+DRG S+E + LLLA K+ Y E +L N
Sbjct: 64 IHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGN 123
Query: 124 HESRQITQVYHSYEECLRKHG----------------NANGDGQLFCLHGGLSPSVDTLH 167
HE I ++Y Y+EC R+ A D ++FC HGGLSP + ++
Sbjct: 124 HECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 183
Query: 168 HIRTLNCLQKIPHEGPMGDLLYSDPDDH-----------------DTPETFNHASGLRLV 210
IR + +P G + DLL+SDPD D F + L L+
Sbjct: 184 QIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLI 243
Query: 211 SRAHQLVMVGHNWCHDWNVVAIFSTPNYC 239
RAHQ+V G+ + +V +FS PNYC
Sbjct: 244 CRAHQVVEDGYEFFAKRQLVTLFSAPNYC 272
>gi|4506005 protein phosphatase 1, catalytic subunit, beta isoform 1
[Homo sapiens]
Length = 327
Score = 118 bits (296), Expect = 4e-27
Identities = 80/269 (29%), Positives = 117/269 (43%), Gaps = 55/269 (20%)
Query: 26 GSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGD 85
G V S LL + + + +V+ LC +++EI + E+ P+ + GD
Sbjct: 4 GELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGD 63
Query: 86 KHGQ----------------------GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRN 123
HGQ GDY+DRG S+E + LLLA K+ Y E +L N
Sbjct: 64 IHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGN 123
Query: 124 HESRQITQVYHSYEECLRKHG----------------NANGDGQLFCLHGGLSPSVDTLH 167
HE I ++Y Y+EC R+ A D ++FC HGGLSP + ++
Sbjct: 124 HECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 183
Query: 168 HIRTLNCLQKIPHEGPMGDLLYSDPDDH-----------------DTPETFNHASGLRLV 210
IR + +P G + DLL+SDPD D F + L L+
Sbjct: 184 QIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLI 243
Query: 211 SRAHQLVMVGHNWCHDWNVVAIFSTPNYC 239
RAHQ+V G+ + +V +FS PNYC
Sbjct: 244 CRAHQVVEDGYEFFAKRQLVTLFSAPNYC 272
>gi|45827798 protein phosphatase 1, catalytic subunit, alpha isoform
2 [Homo sapiens]
Length = 286
Score = 108 bits (271), Expect = 3e-24
Identities = 65/183 (35%), Positives = 91/183 (49%), Gaps = 33/183 (18%)
Query: 90 GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG----- 144
GDY+DRG S+E + LLLA K+ Y E +L NHE I ++Y Y+EC R++
Sbjct: 47 GDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWK 106
Query: 145 -----------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPD 193
A D ++FC HGGLSP + ++ IR + +P +G + DLL+SDPD
Sbjct: 107 TFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPD 166
Query: 194 ---------DHDTPETFN--------HASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTP 236
D TF H L L+ RAHQ+V G+ + +V +FS P
Sbjct: 167 KDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAP 226
Query: 237 NYC 239
NYC
Sbjct: 227 NYC 229
>gi|194688149 protein phosphatase 3, catalytic subunit, alpha
isoform isoform 3 [Homo sapiens]
Length = 469
Score = 107 bits (268), Expect = 8e-24
Identities = 76/245 (31%), Positives = 108/245 (44%), Gaps = 68/245 (27%)
Query: 62 EAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRGYYS 99
E IL +E N ++ PVTV GD HGQ GDY+DRGY+S
Sbjct: 67 EGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFS 126
Query: 100 IEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGDG--------- 150
IE V+ L A+K+ Y + + +L NHE R +T+ + +EC K+ D
Sbjct: 127 IECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLP 186
Query: 151 -------QLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP----DDHDTPE 199
Q C+HGGLSP ++TL IR L+ ++ P GPM D+L+SDP + T E
Sbjct: 187 LAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQE 246
Query: 200 TFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVVAIF 233
F H + L + RAH+ G+ +++ IF
Sbjct: 247 HFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIF 306
Query: 234 STPNY 238
S PNY
Sbjct: 307 SAPNY 311
>gi|194688147 protein phosphatase 3, catalytic subunit, alpha
isoform isoform 2 [Homo sapiens]
Length = 511
Score = 107 bits (268), Expect = 8e-24
Identities = 76/245 (31%), Positives = 108/245 (44%), Gaps = 68/245 (27%)
Query: 62 EAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRGYYS 99
E IL +E N ++ PVTV GD HGQ GDY+DRGY+S
Sbjct: 67 EGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFS 126
Query: 100 IEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGDG--------- 150
IE V+ L A+K+ Y + + +L NHE R +T+ + +EC K+ D
Sbjct: 127 IECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLP 186
Query: 151 -------QLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP----DDHDTPE 199
Q C+HGGLSP ++TL IR L+ ++ P GPM D+L+SDP + T E
Sbjct: 187 LAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQE 246
Query: 200 TFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVVAIF 233
F H + L + RAH+ G+ +++ IF
Sbjct: 247 HFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIF 306
Query: 234 STPNY 238
S PNY
Sbjct: 307 SAPNY 311
>gi|6715568 protein phosphatase 3, catalytic subunit, alpha isoform
isoform 1 [Homo sapiens]
Length = 521
Score = 107 bits (268), Expect = 8e-24
Identities = 76/245 (31%), Positives = 108/245 (44%), Gaps = 68/245 (27%)
Query: 62 EAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRGYYS 99
E IL +E N ++ PVTV GD HGQ GDY+DRGY+S
Sbjct: 67 EGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFS 126
Query: 100 IEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGDG--------- 150
IE V+ L A+K+ Y + + +L NHE R +T+ + +EC K+ D
Sbjct: 127 IECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLP 186
Query: 151 -------QLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP----DDHDTPE 199
Q C+HGGLSP ++TL IR L+ ++ P GPM D+L+SDP + T E
Sbjct: 187 LAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQE 246
Query: 200 TFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVVAIF 233
F H + L + RAH+ G+ +++ IF
Sbjct: 247 HFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIF 306
Query: 234 STPNY 238
S PNY
Sbjct: 307 SAPNY 311
>gi|215272354 protein phosphatase 3, catalytic subunit, beta isoform
c [Homo sapiens]
Length = 515
Score = 102 bits (253), Expect = 4e-22
Identities = 75/248 (30%), Positives = 106/248 (42%), Gaps = 68/248 (27%)
Query: 59 LCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRG 96
+ E IL E EV P+TV GD HGQ GDY+DRG
Sbjct: 73 IINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG 132
Query: 97 YYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGN----------- 145
Y+SIE V+ L +K+ Y + +L NHE R +T+ + +EC K+
Sbjct: 133 YFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFD 192
Query: 146 -----ANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDD----HD 196
A + Q C+HGGLSP + TL IR L+ ++ P GPM DLL+SDP +
Sbjct: 193 SLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEK 252
Query: 197 TPETFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVV 230
+ E F+H + L + RAH+ G+ +++
Sbjct: 253 SQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLI 312
Query: 231 AIFSTPNY 238
IFS PNY
Sbjct: 313 TIFSAPNY 320
>gi|215272352 protein phosphatase 3, catalytic subunit, beta isoform
a [Homo sapiens]
Length = 525
Score = 102 bits (253), Expect = 4e-22
Identities = 75/248 (30%), Positives = 106/248 (42%), Gaps = 68/248 (27%)
Query: 59 LCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRG 96
+ E IL E EV P+TV GD HGQ GDY+DRG
Sbjct: 73 IINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG 132
Query: 97 YYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGN----------- 145
Y+SIE V+ L +K+ Y + +L NHE R +T+ + +EC K+
Sbjct: 133 YFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFD 192
Query: 146 -----ANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDD----HD 196
A + Q C+HGGLSP + TL IR L+ ++ P GPM DLL+SDP +
Sbjct: 193 SLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEK 252
Query: 197 TPETFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVV 230
+ E F+H + L + RAH+ G+ +++
Sbjct: 253 SQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLI 312
Query: 231 AIFSTPNY 238
IFS PNY
Sbjct: 313 TIFSAPNY 320
>gi|11036640 protein phosphatase 3, catalytic subunit, beta isoform
b [Homo sapiens]
Length = 524
Score = 102 bits (253), Expect = 4e-22
Identities = 75/248 (30%), Positives = 106/248 (42%), Gaps = 68/248 (27%)
Query: 59 LCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRG 96
+ E IL E EV P+TV GD HGQ GDY+DRG
Sbjct: 73 IINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG 132
Query: 97 YYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGN----------- 145
Y+SIE V+ L +K+ Y + +L NHE R +T+ + +EC K+
Sbjct: 133 YFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFD 192
Query: 146 -----ANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDD----HD 196
A + Q C+HGGLSP + TL IR L+ ++ P GPM DLL+SDP +
Sbjct: 193 SLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEK 252
Query: 197 TPETFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVV 230
+ E F+H + L + RAH+ G+ +++
Sbjct: 253 SQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLI 312
Query: 231 AIFSTPNY 238
IFS PNY
Sbjct: 313 TIFSAPNY 320
>gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Homo
sapiens]
Length = 512
Score = 98.2 bits (243), Expect = 6e-21
Identities = 70/248 (28%), Positives = 107/248 (43%), Gaps = 68/248 (27%)
Query: 59 LCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRG 96
+ + IL +E EV P+TV GD HGQ GDY+DRG
Sbjct: 60 IINDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRG 119
Query: 97 YYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGDG------ 150
Y+SIE V+ L ++K+++ + + +L NHE R +T + +EC K+ D
Sbjct: 120 YFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFD 179
Query: 151 ----------QLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP-DDHDTPE 199
Q C+HGG+SP + +L IR L+ + P GP+ DLL+SDP +D+ +
Sbjct: 180 CLPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEK 239
Query: 200 TFNH-----------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVV 230
T H + L + RAH+ G+ +++
Sbjct: 240 TLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLI 299
Query: 231 AIFSTPNY 238
IFS PNY
Sbjct: 300 TIFSAPNY 307
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 85.5 bits (210), Expect = 4e-17
Identities = 65/242 (26%), Positives = 100/242 (41%), Gaps = 60/242 (24%)
Query: 62 EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 94
+ KE+L++ S E +TV GD HGQ GD++D
Sbjct: 215 QVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVD 274
Query: 95 RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGD----- 149
RG +S+E+++ L K+ Y + +L NHE+ + Q+Y E K+ +
Sbjct: 275 RGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEV 334
Query: 150 -----------GQLFCLHGGL-SPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDDH-- 195
G++ +HGGL S TL IR + ++ P GPM DLL+SDP
Sbjct: 335 FEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNG 394
Query: 196 --------------DTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCYH 241
D + F + L + R+H++ G+ H V +FS PNYC
Sbjct: 395 RSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQ 454
Query: 242 CG 243
G
Sbjct: 455 MG 456
>gi|23312374 protein phosphatase with EF hand calcium-binding domain
1 isoform 1b [Homo sapiens]
Length = 625
Score = 54.7 bits (130), Expect = 8e-08
Identities = 62/256 (24%), Positives = 96/256 (37%), Gaps = 80/256 (31%)
Query: 62 EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 94
E K++L + N + VT+ GD HG+ GD++D
Sbjct: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204
Query: 95 RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRK---HGN------ 145
RG SIEI+M+L + Y + + NHE + Y +E L K HG
Sbjct: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264
Query: 146 ----------ANGDGQLFCLHGGLSPSVDT--LHHIRTLNCLQKI---PHE--------- 181
D ++ +HGG+S + D LH + N ++ + P E
Sbjct: 265 EEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVER-NKMKSVLIPPTETNRDHDTDS 323
Query: 182 --GPMGDLLYSDPDDH-----------------DTPETFNHASGLRLVSRAHQLVMVGHN 222
+ D+L+SDP D + L+++ R+H+ G+
Sbjct: 324 KHNKIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYE 383
Query: 223 WCHDWNVVAIFSTPNY 238
CHD VV IFS NY
Sbjct: 384 ICHDGKVVTIFSASNY 399
>gi|23312378 protein phosphatase with EF hand calcium-binding domain
1 isoform 3 [Homo sapiens]
Length = 591
Score = 50.1 bits (118), Expect = 2e-06
Identities = 59/232 (25%), Positives = 86/232 (37%), Gaps = 66/232 (28%)
Query: 62 EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 94
E K++L + N + VT+ GD HG+ GD++D
Sbjct: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204
Query: 95 RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRK---HG------- 144
RG SIEI+M+L + Y + + NHE + Y +E L K HG
Sbjct: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264
Query: 145 ---------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPD-- 193
D ++ +HGG+S + D LN L ++ M +L +
Sbjct: 265 EEFYAWLPIGTIVDNEILVIHGGISETTD-------LNLLHRV-ERNKMKSVLIPPTETN 316
Query: 194 -DHDTPETFNHASGLRLVSRAHQLVMVG-----HNWCHDW-NVVAIFSTPNY 238
DHDT N + AH + H H+W VV IFS NY
Sbjct: 317 RDHDTDSKHNKVG---VTFNAHGRIKTNGSPTEHLTEHEWEQVVTIFSASNY 365
>gi|23312380 protein phosphatase with EF hand calcium-binding domain
1 isoform 1 [Homo sapiens]
Length = 653
Score = 47.8 bits (112), Expect = 9e-06
Identities = 63/283 (22%), Positives = 95/283 (33%), Gaps = 106/283 (37%)
Query: 62 EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 94
E K++L + N + VT+ GD HG+ GD++D
Sbjct: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204
Query: 95 RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRK---HG------- 144
RG SIEI+M+L + Y + + NHE + Y +E L K HG
Sbjct: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264
Query: 145 ---------NANGDGQLFCLHGGLSPSVD--TLHHIR----------------------- 170
D ++ +HGG+S + D LH +
Sbjct: 265 EEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSK 324
Query: 171 ------TLNCLQKIPHEG------------PMGDLLYSDPDDH----------------- 195
T N +I G + D+L+SDP
Sbjct: 325 HNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGP 384
Query: 196 DTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNY 238
D + L+++ R+H+ G+ CHD VV IFS NY
Sbjct: 385 DVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNY 427
>gi|23312386 serine/threonine protein phosphatase with EF-hand
motifs 2 [Homo sapiens]
Length = 753
Score = 43.5 bits (101), Expect = 2e-04
Identities = 43/160 (26%), Positives = 62/160 (38%), Gaps = 46/160 (28%)
Query: 51 LGSRKVKSLCKEAKEILTEESNAQEVWC----PVTVSGDKHGQ----------------- 89
L +R V +L E K+ L + N V +TV GD HGQ
Sbjct: 141 LHARYVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFIFYKNGLPSPE 200
Query: 90 ------GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRK- 142
GD++DRG S+EI+M+L A + Y + + NHE + Y +E + K
Sbjct: 201 RSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKY 260
Query: 143 --HGN----------------ANGDGQLFCLHGGLSPSVD 164
HG D ++ LHGG+S D
Sbjct: 261 KVHGKEILRTLQDVFCWLPLATLIDEKVLILHGGVSDITD 300
Score = 30.0 bits (66), Expect = 2.0
Identities = 11/32 (34%), Positives = 20/32 (62%)
Query: 207 LRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNY 238
++ + R+H+ G+ +CH+ V+ IFS NY
Sbjct: 481 MQFLIRSHECKPEGYEFCHNRKVLTIFSASNY 512
>gi|239756297 PREDICTED: hypothetical protein [Homo sapiens]
Length = 525
Score = 30.4 bits (67), Expect = 1.6
Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 3/45 (6%)
Query: 2 RQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAA 46
R ++ G A +P P R C G+RGV S LL +PAP++A
Sbjct: 377 RSELAPPGAQDALSPD--PERPCPGTRGVRSGREGLL-SPAPRSA 418
>gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo
sapiens]
Length = 800
Score = 30.4 bits (67), Expect = 1.6
Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 3/45 (6%)
Query: 2 RQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAA 46
R ++ G A +P P R C G+RGV S LL +PAP++A
Sbjct: 477 RSELAPPGARDALSPD--PERPCPGTRGVRSGREGLL-SPAPRSA 518
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,366,194
Number of Sequences: 37866
Number of extensions: 560927
Number of successful extensions: 2145
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 2051
Number of HSP's gapped (non-prelim): 57
length of query: 254
length of database: 18,247,518
effective HSP length: 100
effective length of query: 154
effective length of database: 14,460,918
effective search space: 2226981372
effective search space used: 2226981372
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.