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Search of human proteins with 239747174
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239747174 PREDICTED: hypothetical protein XP_002343931,
partial [Homo sapiens]
(213 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 429 e-121
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 208 2e-54
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 197 6e-51
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 195 2e-50
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 188 3e-48
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 180 7e-46
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 175 3e-44
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 139 2e-33
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 139 2e-33
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 134 6e-32
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 134 7e-32
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 127 9e-30
gi|148746195 trichohyalin [Homo sapiens] 113 1e-25
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 110 7e-25
gi|52426743 cisplatin resistance-associated overexpressed protei... 107 6e-24
gi|19923485 cisplatin resistance-associated overexpressed protei... 107 6e-24
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 107 6e-24
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 107 1e-23
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 103 1e-22
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 103 1e-22
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi... 102 2e-22
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 100 9e-22
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 99 2e-21
gi|213385278 TNF receptor-associated factor 3 interacting protei... 98 5e-21
gi|20070262 TNF receptor-associated factor 3 interacting protein... 98 5e-21
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 97 1e-20
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 95 4e-20
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 94 9e-20
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 92 2e-19
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 92 3e-19
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 429 bits (1103), Expect = e-121
Identities = 213/213 (100%), Positives = 213/213 (100%)
Query: 1 MESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDR 60
MESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDR
Sbjct: 1 MESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDR 60
Query: 61 DREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVR 120
DREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVR
Sbjct: 61 DREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVR 120
Query: 121 DREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRE 180
DREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRE
Sbjct: 121 DREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRE 180
Query: 181 TKERERHTDMERERQRETDRKRDRQRESERERD 213
TKERERHTDMERERQRETDRKRDRQRESERERD
Sbjct: 181 TKERERHTDMERERQRETDRKRDRQRESERERD 213
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 208 bits (530), Expect = 2e-54
Identities = 102/206 (49%), Positives = 148/206 (71%), Gaps = 7/206 (3%)
Query: 11 HTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQ------RDRERNRERDRDRER 64
H + + DR+R R++E +R R++ + + DR ER R+ RDR R R+RDR++ER
Sbjct: 46 HKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKER 105
Query: 65 EKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRER 124
E+QTDRE +RQRE+ER+R ++RE E ER+ ER DR T+ RER++Q++ E ER R +R
Sbjct: 106 ERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDR 165
Query: 125 EKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKER 184
E+Q++ R RQ +RE ++ R+ + ERER+ +E KTEDRH ER RER+RERE + ET ER
Sbjct: 166 ERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETET-ER 224
Query: 185 ERHTDMERERQRETDRKRDRQRESER 210
+R TD ER+RQR+T+R+R++Q E ER
Sbjct: 225 KRQTDRERDRQRKTEREREKQAERER 250
Score = 206 bits (525), Expect = 9e-54
Identities = 122/253 (48%), Positives = 161/253 (63%), Gaps = 44/253 (17%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTE-DRHSERDRQRDRERNRERDR 60
E + E R T ET DR+RERRRE DR R R + + + DR ER+RQ DRER+R+R++
Sbjct: 63 ERRREKRQTERET---DRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREK 119
Query: 61 DREREKQTDREGERQRERERDR--DRQRETERERDKERETDRHTETDRERQ----KQKER 114
+R R+K+ +RE ER+ ER RDR D QRE ER+RD E+E +R T+ +R+RQ +QKER
Sbjct: 120 ERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKER 179
Query: 115 EME---------------------------RVRDREREKQKEMGRERQTDRETDRERERQ 147
E E R R+RERE + E R+RQTDRE DR+R+ +
Sbjct: 180 EREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTE 239
Query: 148 AERERETGRERKTE---DRHRERERERKRERERKRETKERERHTDMER----ERQRETDR 200
ERE++ RER +E +R +ERERER R+R+R R KERER TD +R ER RET+R
Sbjct: 240 REREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETER 299
Query: 201 KRDRQRESERERD 213
KR+RQRE ERER+
Sbjct: 300 KRERQRERERERE 312
Score = 200 bits (509), Expect = 7e-52
Identities = 109/212 (51%), Positives = 156/212 (73%), Gaps = 17/212 (8%)
Query: 18 DRQRERRRETDRERDRAKESKTEDRHSERDRQRDRE-----RNRERDRDREREKQTDREG 72
DR+R+R+ E +R+++R +E ++R ER+RQR++E R+ ER R+RERE++T+ E
Sbjct: 164 DRERQRQTERNRQKEREREKNRQERR-ERERQREKENKTEDRHSERGRERERERETETET 222
Query: 73 ERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDR-----EREKQ 127
ER+R+ +R+RDRQR+TERER+K+ E +R +E + ER K++ERE +R RDR ERE+Q
Sbjct: 223 ERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ 282
Query: 128 KEMGRERQT--DRETDRERERQAERERETGRERKTE-DRHRERERERKRERERKRE---T 181
+ R+R+T DRET+R+RERQ ERERE R RK E +R RERERER+RE ER RE
Sbjct: 283 TDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERE 342
Query: 182 KERERHTDMERERQRETDRKRDRQRESERERD 213
++R+R T+M+RER R+T R+ RQ E ERER+
Sbjct: 343 RKRKRQTEMDRERNRQTGREGRRQAERERERE 374
Score = 200 bits (509), Expect = 7e-52
Identities = 114/256 (44%), Positives = 175/256 (68%), Gaps = 46/256 (17%)
Query: 2 ESKTEGRHTH----------TETET-----MDRQRERRRETDRERDR-AKESKTEDRHSE 45
E+KTE RH+ TETET DR+R+R+R+T+RER++ A+ + +R +E
Sbjct: 198 ENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETE 257
Query: 46 RDRQRDRERNRERDRDR---EREKQTDREGERQRERERDRDRQRETERERDKERETDRHT 102
RD++R+RER+R+RDRDR ERE+QTDR+ +R+ ER+R+ +R+RE +RER++ERE +R
Sbjct: 258 RDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKR 317
Query: 103 ETDRERQKQKEREMERVRDREREKQKEMGRERQTDRE----TDRERERQAERERETGRER 158
E +RER++++ER+ E RDRE+E++++ R+ + DRE T RE RQAERERE RER
Sbjct: 318 ERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERER 377
Query: 159 ------KTEDRHRERERERKRERERK--------RET-KERERHTDME--------RERQ 195
+ E+R R+R+R+R++ERER+ RET K+RER D E RER+
Sbjct: 378 DRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE 437
Query: 196 RETDRKRDRQRESERE 211
++ R+RDR+R+++R+
Sbjct: 438 KQKGRERDRERQTDRQ 453
Score = 200 bits (508), Expect = 9e-52
Identities = 105/243 (43%), Positives = 160/243 (65%), Gaps = 33/243 (13%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
E +T+ + +RQ+ER RET+RE +R ++ +T D ER+RQRD E+ RER D
Sbjct: 106 ERQTDRERDRQREKERNRQKERERETEREGERGRDRQT-DGQRERERQRDAEKERERQTD 164
Query: 62 REREKQTDREGERQRERERDRDRQRETERERDKE-------------RETDRHTETDRER 108
RER++QT+R +++RERE++R +RE ER+R+KE RE +R TET+ ER
Sbjct: 165 RERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETER 224
Query: 109 QKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRE-- 166
++Q +RE +R R ERE++K+ RER ++RET+R++ER+ ER+R+ R+R+ ++R R+
Sbjct: 225 KRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTD 284
Query: 167 ----------------RERERKRERERKRETK-ERERHTDMERERQRETDRKRDRQRESE 209
RER+R+RERER+R K ERER + ERERQRET+R R+++RE +
Sbjct: 285 RKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERK 344
Query: 210 RER 212
R+R
Sbjct: 345 RKR 347
Score = 197 bits (502), Expect = 4e-51
Identities = 119/231 (51%), Positives = 161/231 (69%), Gaps = 29/231 (12%)
Query: 8 RHTHTETETMDRQRERRRET------DRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
R +TE +RQ+ER RE +RER R KE+KTEDRHSER R+R+RER E + +
Sbjct: 165 RERQRQTER-NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERER--ETETE 221
Query: 62 REREKQTDREGERQRERERDRDRQRETER------ERDKERETDRHTETDRER-QKQKER 114
ER++QTDRE +RQR+ ER+R++Q E ER ERDKERE +R + DR+R QK++ER
Sbjct: 222 TERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERER 281
Query: 115 EMERVR------DREREKQKEMGRERQTDRETDRERERQAERERETGRERKTE-DRHRER 167
+ +R R DRE E+++E RER+ +RE +R+RER+ ERERE R+R+TE DR +ER
Sbjct: 282 QTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKER 341
Query: 168 ERERKR----ERERKRET-KERERHTDMERERQRETDRKRDRQRESERERD 213
ER+RKR +RER R+T +E R + ERER+RE DR+ R+RE ERERD
Sbjct: 342 ERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARERE-ERERD 391
Score = 184 bits (466), Expect = 6e-47
Identities = 99/219 (45%), Positives = 148/219 (67%), Gaps = 27/219 (12%)
Query: 19 RQRERRRETDRERDRAKESKTEDRHS-ERDRQRDRERNRERDRDREREKQTDREGERQRE 77
R+R +E+ R R + K D ER+RQ++RER RE+ R+ E++TDR+ ER+RE
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREK---RQTERETDRKRERRRE 84
Query: 78 RERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTD 137
++R R R R ER+RD+E+E +R T+ +R+RQ++KER ++ R+RE E++ E GR+RQTD
Sbjct: 85 KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD 144
Query: 138 RETDRERERQA--ERERETGRER-------KTEDRHRERERERKRERERKRE-------- 180
+ +RER+R A ERER+T RER + ++R RE+ R+ +RERER+RE
Sbjct: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR 204
Query: 181 ------TKERERHTDMERERQRETDRKRDRQRESERERD 213
+ERER T+ E ER+R+TDR+RDRQR++ERER+
Sbjct: 205 HSERGRERERERETETETERKRQTDRERDRQRKTERERE 243
Score = 155 bits (393), Expect = 2e-38
Identities = 91/196 (46%), Positives = 131/196 (66%), Gaps = 30/196 (15%)
Query: 8 RHTHTETETMDRQRERRRETDRERDRAKESKTE-DRHSERDRQRDRERNRERDRDREREK 66
R E +T DR+R+RR E DRE +R +E + E +R ER+R+R+RER RER+R+R+RE
Sbjct: 275 RQKERERQT-DRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRET 333
Query: 67 QTDREGERQRERER----DRDRQRET--------ERERDKERETDRHT---------ETD 105
+ DRE ER+R+R+R DR+R R+T ERER++ERE DR + + D
Sbjct: 334 ERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRD 393
Query: 106 RERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHR 165
R+RQK++ER+ E+ RD +RE +K+ RER+ DRE++R RER ERE++ GRE R R
Sbjct: 394 RDRQKERERQTEKDRDGQRETEKQ--REREKDRESERGRERGREREKQKGRE-----RDR 446
Query: 166 ERERERKRERERKRET 181
ER+ +R+ R+RKR T
Sbjct: 447 ERQTDRQAGRQRKRST 462
Score = 139 bits (350), Expect = 2e-33
Identities = 74/164 (45%), Positives = 109/164 (66%), Gaps = 16/164 (9%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQR------DRERN 55
E K E + +R+RER RE +RER+R +E++ DR ER+R+R DRERN
Sbjct: 298 ERKRERQRERERERERNRKRERERERERERERQRETE-RDREKERERKRKRQTEMDRERN 356
Query: 56 RER--------DRDREREKQTDREGERQRE-RERDRDRQRETERERDKERETDRHTETDR 106
R+ +R+RERE++ DR+ R+RE RERDRDR R+ ERER E++ D ET++
Sbjct: 357 RQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEK 416
Query: 107 ERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAER 150
+R+++K+RE ER R+R RE++K+ GRER +R+TDR+ RQ +R
Sbjct: 417 QREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
Score = 138 bits (347), Expect = 4e-33
Identities = 77/174 (44%), Positives = 116/174 (66%), Gaps = 13/174 (7%)
Query: 51 DRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQK 110
D R R ++ R + + + +R+R+RQ+E ER R+K R+T+R T+ RER++
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREK-RQTERETDRKRERRR 83
Query: 111 QKEREMERVRDREREKQKEMGRERQTDRETDRERE----RQAERERET------GRERKT 160
+K+R +R R RER++ +E RERQTDRE DR+RE RQ ERERET GR+R+T
Sbjct: 84 EKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQT 143
Query: 161 EDRHRERERERKRERERKRET-KERERHTDMERERQRETDRKRDRQRESERERD 213
D RERER+R E+ER+R+T +ER+R T+ R+++RE ++ R +RE ER+R+
Sbjct: 144 -DGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQRE 196
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 197 bits (501), Expect = 6e-51
Identities = 111/213 (52%), Positives = 146/213 (68%), Gaps = 15/213 (7%)
Query: 11 HTETETMDRQRER---RRETDRERDRAKESKTEDRHSERD--RQRDRERNRERDRDRERE 65
H + + DRQRER R +T++ERDR ++ E R E++ R RDRE+ E +RDRERE
Sbjct: 69 HKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRERE 128
Query: 66 KQTDREGERQRERERDRDRQRETERER------DKERETDRHTETDRERQKQKEREMERV 119
KQ RE ER R RER+RDR RE ERER D +RET+ E DRER+KQKERE ER
Sbjct: 129 KQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERD 188
Query: 120 RDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTE-DRHRERERERKRERERK 178
RDR+R+ +KE RERQTDRE DR+R+ Q ER+RET RE + E DR RER+R+R R +ER
Sbjct: 189 RDRQRDTEKE--RERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERD 246
Query: 179 RETKERERHTDMERERQRETDRKRDRQRESERE 211
RE ++R+ ER+++R+ +RK ++ E RE
Sbjct: 247 RE-RDRKEERKKERKKERKKERKEKKKEEKRRE 278
Score = 166 bits (419), Expect = 2e-41
Identities = 88/198 (44%), Positives = 137/198 (69%), Gaps = 20/198 (10%)
Query: 35 KESKTEDRHSERDRQRDR---ERNRERDRDRER---EKQTDREGERQRERERDRDRQRET 88
K++ +DR ERDR R++ ER+R+R RDRER EK+T+R +R+++ E +RDR+RE
Sbjct: 70 KDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREK 129
Query: 89 ERERDKERETDRHTETDRERQKQKER------------EMERVRDREREKQKEMGRERQT 136
++ R++ER+ R E DR+R+K++ER E ER RDREREKQKE ER
Sbjct: 130 QKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDR 189
Query: 137 DRETDRERERQAERERETGRERKTE-DRHRERERERKRERERKRE-TKERERHTDMERER 194
DR+ D E+ER+ + +RE R+RKT+ +R RE +RE +RE +R+RE ++R+R + +RER
Sbjct: 190 DRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRER 249
Query: 195 QRETDRKRDRQRESERER 212
R+ +RK++R++E ++ER
Sbjct: 250 DRKEERKKERKKERKKER 267
Score = 165 bits (417), Expect = 3e-41
Identities = 95/213 (44%), Positives = 143/213 (67%), Gaps = 26/213 (12%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
+ K + E ET +R R+R ++T+ ERDR +E K + R ERDR R+RER+R+R+++
Sbjct: 95 DRKRDRERRRKEKET-NRNRDREKQTEIERDRERE-KQKGRERERDRGRERERDRDREKE 152
Query: 62 REREKQTDREGERQRE--RERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERV 119
RER+ + DR+G+R+ E RERDR ERE+ KERET+R DR+RQ+ E+E ER
Sbjct: 153 RERQTEKDRDGQRETETERERDR------EREKQKERETER----DRDRQRDTEKERERQ 202
Query: 120 RDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179
DRER++Q++ ERQ RETDRE ER+ +R RE R+R DR +ER+RER R+ ERK+
Sbjct: 203 TDRERDRQRKTQTERQ--RETDREGERETDRRRERQRDR---DRGKERDRERDRKEERKK 257
Query: 180 ETKERERHTDMERERQRETDRKRDRQRESERER 212
E K+ ER+++R+ +K +++RE ++ +
Sbjct: 258 ERKK-------ERKKERKEKKKEEKRREDKKRK 283
Score = 149 bits (376), Expect = 2e-36
Identities = 88/210 (41%), Positives = 137/210 (65%), Gaps = 17/210 (8%)
Query: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDR 62
S T H H+ T+ + + R R ++ES + + D + +R+R+RDR
Sbjct: 25 SLTYAPHLHSSLGTLWVEVTIPLDFSRGRLGSQESPRSWGLGQAHKDADGD-DRQRERDR 83
Query: 63 EREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDR 122
REK E+ERDRDR+R+ ER R KE+ET+R+ DRE+Q + ER+ ER + +
Sbjct: 84 VREKT---------EKERDRDRKRDRERRR-KEKETNRNR--DREKQTEIERDREREKQK 131
Query: 123 EREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETK 182
RE++++ GRER+ DR+ ++ERERQ E++R+ RE +TE R R+RERE+++ERE +R+
Sbjct: 132 GRERERDRGRERERDRDREKERERQTEKDRDGQRETETE-RERDREREKQKERETERD-- 188
Query: 183 ERERHTDMERERQRETDRKRDRQRESERER 212
R+R D E+ER+R+TDR+RDRQR+++ ER
Sbjct: 189 -RDRQRDTEKERERQTDRERDRQRKTQTER 217
Score = 69.7 bits (169), Expect = 2e-12
Identities = 39/100 (39%), Positives = 63/100 (63%), Gaps = 8/100 (8%)
Query: 118 RVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERER 177
R+ +E + +G+ + DR+RER RE+ T +ER DR R+R+RER+R+ +
Sbjct: 53 RLGSQESPRSWGLGQAHKDADGDDRQRERDRVREK-TEKER---DRDRKRDRERRRKEKE 108
Query: 178 KRETKERERHTDMERERQRET----DRKRDRQRESERERD 213
++RE+ T++ER+R+RE +R+RDR RE ER+RD
Sbjct: 109 TNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRD 148
Score = 52.0 bits (123), Expect = 4e-07
Identities = 29/78 (37%), Positives = 47/78 (60%), Gaps = 2/78 (2%)
Query: 137 DRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERER-Q 195
D R +++ R G+ K D +R+RER R RE+ + ++R+R D ER R +
Sbjct: 48 DFSRGRLGSQESPRSWGLGQAHKDADGD-DRQRERDRVREKTEKERDRDRKRDRERRRKE 106
Query: 196 RETDRKRDRQRESERERD 213
+ET+R RDR++++E ERD
Sbjct: 107 KETNRNRDREKQTEIERD 124
Score = 48.1 bits (113), Expect = 5e-06
Identities = 27/63 (42%), Positives = 42/63 (66%), Gaps = 4/63 (6%)
Query: 13 ETETMDRQRERRRETDR--ERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDR 70
E ET DR+RER+R+ DR ERDR ++ K E+R ER ++R +ER ++ ++ RE + +
Sbjct: 226 ERET-DRRRERQRDRDRGKERDRERDRK-EERKKERKKERKKERKEKKKEEKRREDKKRK 283
Query: 71 EGE 73
GE
Sbjct: 284 WGE 286
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 195 bits (496), Expect = 2e-50
Identities = 112/229 (48%), Positives = 151/229 (65%), Gaps = 23/229 (10%)
Query: 1 MESKTEGRHTHTETETMDRQRERRRETDRE-RDRAKESKTEDRHSERDRQRDRER----- 54
++S + + H ET ER R +R+ RD+A++S E RH ERDR+ +RER
Sbjct: 583 IDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPS 642
Query: 55 --------NRERDRDRERE-KQTDREGERQRERERDRDRQRETERERDKERETDRHTETD 105
N E +RD RE ++ DR +R+ ER R+RDR+RE +RER++ERE +R D
Sbjct: 643 SPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERER----D 698
Query: 106 RERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHR 165
RER+K++E E ER R+RERE++KE RER DR+ DRERER+ ER+RE RER+ E+R R
Sbjct: 699 REREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERER 758
Query: 166 ERERERKRERERKRETKERERHTDMERERQR---ETDRKRDRQRESERE 211
ERERER+RERER+RE +ER R D ERERQR + D+ RD +RE E
Sbjct: 759 ERERERERERERERE-RERARERDKERERQRDWEDKDKGRDDRREKREE 806
Score = 166 bits (419), Expect = 2e-41
Identities = 77/194 (39%), Positives = 130/194 (67%), Gaps = 1/194 (0%)
Query: 21 RERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERER 80
R E D R+ + + +DR ER R+RDRER R+R+R+RERE++ DRE E++RE ER
Sbjct: 650 RNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELER 709
Query: 81 DRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRER-EKQKEMGRERQTDRE 139
+R R+RE ERE++++RE DR + DRER++++ER+ E+ R+RER E+++E RER+ +RE
Sbjct: 710 ERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERE 769
Query: 140 TDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETD 199
+RERER ER++E R+R ED+ + R+ R++ E + + R+ H + + +++ +
Sbjct: 770 RERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNE 829
Query: 200 RKRDRQRESERERD 213
++ +R R+
Sbjct: 830 GSPSPRQSPKRRRE 843
Score = 162 bits (409), Expect = 3e-40
Identities = 87/207 (42%), Positives = 136/207 (65%), Gaps = 8/207 (3%)
Query: 6 EGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRERE 65
+GR+ E + +R R DR +RA+E DR ERDR+R+RER RERDR+RE+E
Sbjct: 648 QGRNDELERDERREERRVDRVDDRRDERARE---RDRERERDRERERERERERDREREKE 704
Query: 66 KQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRERE 125
++ +RE R+RERER+++R RE +R+RD +RE +R E DRE+++++ERE ER R+RERE
Sbjct: 705 RELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERERE-ERERERERE 763
Query: 126 KQKEMGRERQTD--RETDRERERQAE-RERETGRERKTEDRHRERERERKRERERKRETK 182
+++E RER+ + RE D+ERERQ + +++ GR+ + E R RE R+ +R++K
Sbjct: 764 RERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSK 823
Query: 183 ERERHTDMERERQRETDRKRDRQRESE 209
+R R+ RQ R+R+ +S+
Sbjct: 824 KRYRNEGSPSPRQ-SPKRRREHSPDSD 849
Score = 161 bits (408), Expect = 3e-40
Identities = 93/220 (42%), Positives = 139/220 (63%), Gaps = 27/220 (12%)
Query: 2 ESKTEGRHTHTETETMDRQRERR---------RETDRERDRAKESKTEDRHSERDRQRDR 52
+S E RH + +R+R++R R + ERD +E + DR +R +R R
Sbjct: 619 DSSFERRHGERDRRD-NRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERAR 677
Query: 53 ERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQK 112
ER+RER+RDRERE+ ER+RER+R+R+++RE ERER +ERE +R E DRER + +
Sbjct: 678 ERDRERERDRERER------ERERERDREREKERELERERAREREREREKERDRERDRDR 731
Query: 113 EREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERK 172
+ + ER R+RER+++KE RER+ +RE +RERER+ ERERE R RER RER
Sbjct: 732 DHDRERERERERDREKERERERE-ERERERERERERERERE---------RERERARERD 781
Query: 173 RERERKRETKERERHTDMERERQRETDRKRD-RQRESERE 211
+ERER+R+ +++++ D RE++ E R+ R ER+
Sbjct: 782 KERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERK 821
Score = 155 bits (391), Expect = 3e-38
Identities = 82/209 (39%), Positives = 130/209 (62%), Gaps = 8/209 (3%)
Query: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRE 63
+ E R DR+ ER RE DRER+R +E + E R ERDR+R++ER ER+R RE
Sbjct: 656 RDERREERRVDRVDDRRDERARERDRERERDRERERE-RERERDREREKERELERERARE 714
Query: 64 REKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRE 123
RE++ ++E +R+R+R+RD DR+RE ERERD+E+E +R E +RER++++ERE ER R+RE
Sbjct: 715 REREREKERDRERDRDRDHDRERERERERDREKERERERE-ERERERERERERERERERE 773
Query: 124 REKQKEMGRERQTDR---ETDRERERQAERERETGRERKTEDRHRERERERKRERE---R 177
RE+ +E +ER+ R + D+ R+ + E+ E +R D H ER+ +++ E
Sbjct: 774 RERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPS 833
Query: 178 KRETKERERHTDMERERQRETDRKRDRQR 206
R++ +R R + + D K ++ R
Sbjct: 834 PRQSPKRRREHSPDSDAYNSGDDKNEKHR 862
Score = 136 bits (343), Expect = 1e-32
Identities = 83/219 (37%), Positives = 129/219 (58%), Gaps = 26/219 (11%)
Query: 18 DRQRERRRETDRERDRAKESKTE-DRHSERDRQRDRERNRERDRDR------EREKQTDR 70
DR+RER RE +R+R+R KE + E +R ER+R+R++ER+RERDRDR ERE++ DR
Sbjct: 686 DRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDR 745
Query: 71 EGERQRER-ERDRDRQRETERERDKERETDRHTETDRERQKQKE-REMERVRDREREKQK 128
E ER+RER ER+R+R+RE ERER++ERE +R E D+ER++Q++ + ++ RD REK++
Sbjct: 746 EKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKRE 805
Query: 129 EMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERER--------KRERERKRE 180
E+ +R D + ++ R + R++ R RE + K E+ R
Sbjct: 806 EIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLS 865
Query: 181 TKERERH---------TDMERERQRETDRKRDRQRESER 210
R + T+ + R +E DRK +R+ S R
Sbjct: 866 QVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRR 904
Score = 131 bits (330), Expect = 4e-31
Identities = 91/228 (39%), Positives = 127/228 (55%), Gaps = 30/228 (13%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRD---------- 51
ES+ E R + + M R R R E + R D HS D
Sbjct: 546 ESRNESR-SEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPE 604
Query: 52 RERNRERD-RDREREKQTDRE-GERQRERERDRDRQRETERERDKERETDRHTETDRERQ 109
R+R ERD RD+ R+ +R GER R R+RD +R R R+ E +R+ +
Sbjct: 605 RDRYPERDNRDQARDSSFERRHGERDRRDNRERD-----QRPSSPIRHQGRNDELERD-E 658
Query: 110 KQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTE---DRHRE 166
+++ER ++RV DR E R R+ DRE +R+RER+ ERERE RER+ E +R R
Sbjct: 659 RREERRVDRVDDRRDE------RARERDRERERDRERERERERERDREREKERELERERA 712
Query: 167 RERERKRERERKRETKERERHTDMERERQRETDRKRDRQRE-SERERD 213
RERER+RE+ER RE ++R+R D ERER+RE DR+++R+RE ERER+
Sbjct: 713 REREREREKERDRE-RDRDRDHDRERERERERDREKEREREREERERE 759
Score = 107 bits (267), Expect = 8e-24
Identities = 66/198 (33%), Positives = 103/198 (52%), Gaps = 11/198 (5%)
Query: 18 DRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRE 77
DR R+ RE +RER+R +E + E ER+R+R+RER RER+R+RERE+ +R+ ER+R+
Sbjct: 728 DRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQ 787
Query: 78 RE-RDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQT 136
R+ D+D+ R+ RE+ +E DR+ + +K K+R R+ K RE
Sbjct: 788 RDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRR-REHSP 846
Query: 137 DRETDRERERQAERER------ETGRERKTEDRHRERERE-RKRERERKRETKERERHTD 189
D + + + E+ R R H +R+ R +E +RK E KE R
Sbjct: 847 DSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRR-- 904
Query: 190 MERERQRETDRKRDRQRE 207
E + +E D+QRE
Sbjct: 905 YEEQELKEKVSSVDKQRE 922
Score = 98.6 bits (244), Expect = 3e-21
Identities = 72/261 (27%), Positives = 110/261 (42%), Gaps = 76/261 (29%)
Query: 18 DRQRERRRETDRERDRAKESKTE---DRHSERDRQRDRERNRERDRDREREKQTDREG-- 72
DR+RE+ RE +RER R +E + E DR +RDR DRER RER+RDRE+E++ +RE
Sbjct: 698 DREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERE 757
Query: 73 ---ERQRERERDRDRQRETERERDKERET-----------------------DRHTETDR 106
ER+RERER+R+R+RE RERDKERE DR+
Sbjct: 758 RERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGH 817
Query: 107 ERQKQKEREMERVRDREREKQKE------------------------------------- 129
+ +K K+R R+ K
Sbjct: 818 DERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLS 877
Query: 130 --------MGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRET 181
GR ++ DR+ +R+ + E+E + + D+ RE+ + R R ++
Sbjct: 878 PSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDI 937
Query: 182 KERERHTDMERERQRETDRKR 202
+ D E + + K+
Sbjct: 938 IGHHQSEDRETSDRAHDENKK 958
Score = 92.8 bits (229), Expect = 2e-19
Identities = 88/327 (26%), Positives = 126/327 (38%), Gaps = 117/327 (35%)
Query: 4 KTEGRHTHTET-ETMDRQRERRRETDRERDRAKESK------------------------ 38
+ +GRH H T ++ DR+ ERR +T +RDR K+S+
Sbjct: 396 REKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDG 455
Query: 39 --------TEDRHSERDRQRDRERNRERDRDRE-REKQTDREGERQRERERDRDRQ-RET 88
T DR RD + R+ RD R+ +E + R+ R+ RDR+ R+T
Sbjct: 456 RDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDT 515
Query: 89 ERERDKERETDRHTETDRERQKQKEREM---ERVRDREREKQKEMGRER----------- 134
R+ D E R + R++ E+ R R + MGR R
Sbjct: 516 HRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGS 575
Query: 135 ----------------------------QTDRETDRERERQA----------ERERETGR 156
+ DR +R+ QA ER+R R
Sbjct: 576 RGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNR 635
Query: 157 ER-----------------------------KTEDRHRERERERKRERERKRE-TKERER 186
ER + +DR ER RER RERER RE +ERER
Sbjct: 636 ERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERER 695
Query: 187 HTDMERERQRETDRKRDRQRESERERD 213
D ERE++RE +R+R R+RE ERE++
Sbjct: 696 ERDREREKERELERERAREREREREKE 722
Score = 85.1 bits (209), Expect = 4e-17
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 13/189 (6%)
Query: 12 TETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDRE 71
T ++ D + R + E DR S++ S RDR ++R+R E DR+RERE++ R+
Sbjct: 1263 TSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDS-RDRLQERDRY-EHDRERERERRDTRQ 1320
Query: 72 GERQRERERD--RDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKE 129
E R+ ++D R+R R+ RER++ERE D+ + DRER++ +ER RDR+R++ E
Sbjct: 1321 REWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFE 1380
Query: 130 MGR-------ERQTDRETDRERERQAERERETGRERKTEDRHRER--ERERKRERERKRE 180
+ E + + E +R+ E + +ER +D + E K ER E
Sbjct: 1381 SSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLE 1440
Query: 181 TKERERHTD 189
+ E D
Sbjct: 1441 AGDDESKLD 1449
Score = 82.4 bits (202), Expect = 3e-16
Identities = 58/195 (29%), Positives = 97/195 (49%), Gaps = 16/195 (8%)
Query: 7 GRHTHTETETMDRQRERRRETDR-ERDRAKESKTEDRHSERDRQRDRERNRERDRDRERE 65
G +T++++ ER+ D+ +R S + DR R R + DR+
Sbjct: 1231 GSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHS---SRRSSPESDRQVH 1287
Query: 66 KQTDREGERQRERERDR---DRQRETERERDKERETDRHTETDRERQKQKEREMERVRDR 122
++ R R +ERDR DR+RE ER ++RE DR + D R + ++R ER R+R
Sbjct: 1288 SRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERER 1347
Query: 123 EREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRE--RERERKRERERKRE 180
ER+K++++ DRE +R ER+R+ R+R E E + E K E E +R+
Sbjct: 1348 ERDKRRDL------DRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERD 1401
Query: 181 TKERERHT-DMERER 194
+ R + +++ER
Sbjct: 1402 LESTSRDSLALDKER 1416
Score = 80.5 bits (197), Expect = 1e-15
Identities = 60/207 (28%), Positives = 100/207 (48%), Gaps = 23/207 (11%)
Query: 18 DRQRERRR-----ETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREG 72
D Q R+R DRE+ ++ E T +R S D+ + E +R DR+ D
Sbjct: 1219 DDQSGRKRVLHSGSRDREKTKSLEI-TGERKSRIDQLKRGEPSRSTSSDRQ-----DSRS 1272
Query: 73 ERQRERERDRDRQRETER----ERDKERETDRHTETDRERQKQKEREMERVRDREREKQK 128
R + DRQ + RD+ +E DR+ + +R++++ER R R+ +R+ K
Sbjct: 1273 HSSRRSSPESDRQVHSRSGSFDSRDRLQERDRY---EHDRERERERRDTRQREWDRDADK 1329
Query: 129 EMGRERQTDRETDRERERQAERERETGRERK-----TEDRHRERERERKRERERKRETKE 183
+ R R DR +RERER+ ++ R+ RER+ + +R R+R+R+R E + K
Sbjct: 1330 DWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKR 1389
Query: 184 RERHTDMERERQRETDRKRDRQRESER 210
E + E ER E+ + + ER
Sbjct: 1390 CEAKLEGEHERDLESTSRDSLALDKER 1416
Score = 78.6 bits (192), Expect = 4e-15
Identities = 69/295 (23%), Positives = 124/295 (42%), Gaps = 85/295 (28%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
E + E DR +R RE +RERDR KE + E ER+R+R+RER RER+R+
Sbjct: 714 EREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERE 773
Query: 62 REREKQTDREGERQRE----------RERDRDRQRET----------------------- 88
RER ++ D+E ERQR+ R R+ RE
Sbjct: 774 RERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPS 833
Query: 89 -----ERERDKERETDRHTETDRERQKQK--------------------EREMERVRDRE 123
+R R+ ++D + D + +K + E R ++ +
Sbjct: 834 PRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEED 893
Query: 124 REKQKEMGRERQTDRE-------TDRERER----QAERER-------ETGRERKTEDRHR 165
R+ +++ R ++E D++RE+ ++ R R +R+T DR
Sbjct: 894 RKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAH 953
Query: 166 ERERERKRERERKRETKERERHTDMER--------ERQRETDRKRDRQRESERER 212
+ E ++K + ++K K++E +ER + Q + +K +++ E++R
Sbjct: 954 D-ENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKR 1007
Score = 77.0 bits (188), Expect = 1e-14
Identities = 58/178 (32%), Positives = 90/178 (50%), Gaps = 20/178 (11%)
Query: 3 SKTEGRHTHTET---ETMDRQRERRR-ETDRERDRAKESKTE---DRHSERD--RQRDRE 53
S R H+ + ++ DR +ER R E DRER+R + + DR +++D R RDR+
Sbjct: 1279 SPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRD 1338
Query: 54 RNRERDRDREREKQTDREGERQR------ERERDRDRQRETERER-DKERETDRHTETDR 106
R RER+R+RER+K+ D + ER+R ER+RDRDR R E + + + + E +
Sbjct: 1339 RLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEH 1398
Query: 107 ERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRH 164
ER + D+ER K++G + + ER E + E K +D H
Sbjct: 1399 ERDLESTSRDSLALDKER-MDKDLGSVQGFEETNKSERTESLEAGDD---ESKLDDAH 1452
Score = 65.9 bits (159), Expect = 3e-11
Identities = 57/219 (26%), Positives = 97/219 (44%), Gaps = 17/219 (7%)
Query: 5 TEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRER 64
T T+T T + ++ R+ R + K E H + + R+ ++
Sbjct: 1139 TSATPTNTTNNTFANE-----DSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLG 1193
Query: 65 EKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRER 124
+++R R R D + ++ + DRE+ K E ER ++
Sbjct: 1194 SNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQ 1253
Query: 125 EKQKEMGRERQTDRETDRE---RERQAERERETGRER---KTEDRHRERER---ERKRER 175
K+ E R +DR+ R R E +R+ + DR +ER+R +R+RER
Sbjct: 1254 LKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERER 1313
Query: 176 ERKRETKERE--RHTDMERERQRETDRKRDRQRESERER 212
ER R+T++RE R D + R R+ DR R+R+RE ER++
Sbjct: 1314 ER-RDTRQREWDRDADKDWPRNRDRDRLRERERERERDK 1351
Score = 65.5 bits (158), Expect = 3e-11
Identities = 47/180 (26%), Positives = 80/180 (44%), Gaps = 13/180 (7%)
Query: 35 KESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDK 94
K+S R R++ R + DR E++ D G+R DR++ ERE ++
Sbjct: 385 KQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKR------DREKDSREEREYEQ 438
Query: 95 ERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERET 154
++ + R DRE + ++R RD ++ R+ + RE R+ R + R+
Sbjct: 439 DQSSSRDHRDDREPRDGRDR--RDARDTRDRRELRDSRDMRDSREM-RDYSRDTKESRDP 495
Query: 155 GRERKTEDRHRERERERKRERERKRETKERERHT---DMERERQRETDRKRDRQRESERE 211
R T D H R+RE R+ RK +T E + + RE T+ + + + ES E
Sbjct: 496 RDSRSTRDAHDYRDRE-GRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSE 554
Score = 64.7 bits (156), Expect = 6e-11
Identities = 49/187 (26%), Positives = 81/187 (43%), Gaps = 9/187 (4%)
Query: 23 RRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDR 82
R R RE+ R +T H R +R+ R + RDR+++ ++ + E ++ R+
Sbjct: 390 RHRSPMREKGRHDHERTSQSHDRRHERREDTRGK-RDREKDSREEREYEQDQSSSRDHRD 448
Query: 83 DRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRERE-KQKEMGRERQTDRETD 141
DR+ R+R R+T E R + REM RD R+ K+ R+ ++ R+
Sbjct: 449 DREPRDGRDRRDARDTRDRRELRDSRDMRDSREM---RDYSRDTKESRDPRDSRSTRDAH 505
Query: 142 RERERQAERERETGRERKT-EDRHRERERERKRERERKRETKERERHTDMERERQRETDR 200
R+R+ R+T R+ T + R R RE + E + R+ R R
Sbjct: 506 DYRDREG---RDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGR 562
Query: 201 KRDRQRE 207
R R E
Sbjct: 563 SRGRVPE 569
Score = 61.2 bits (147), Expect = 6e-10
Identities = 43/168 (25%), Positives = 70/168 (41%), Gaps = 17/168 (10%)
Query: 43 HSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHT 102
HS QR + R R RE+ + + +R +R +R+R+K+ +R
Sbjct: 377 HSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREY 436
Query: 103 ETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTED 162
E D+ RD +++ GR+R+ R+T RE + R+ RE
Sbjct: 437 EQDQSSS----------RDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREM---- 482
Query: 163 RHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESER 210
R+ R+ K R+ + R+ H +RE R+T RK D E R
Sbjct: 483 --RDYSRDTKESRDPRDSRSTRDAHDYRDRE-GRDTHRKEDTYPEESR 527
Score = 58.2 bits (139), Expect = 5e-09
Identities = 64/266 (24%), Positives = 113/266 (42%), Gaps = 78/266 (29%)
Query: 8 RHTHTETETMDRQRERRRETDRERDRAKE-SKTEDRHSERDRQRDRE-RNRERDRDRE-- 63
R E E +R+RER RE +RER+R +E + +R ER+RQRD E +++ RD RE
Sbjct: 745 REKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKR 804
Query: 64 ---REKQTDREG----------------------ERQRERERDRDRQRETERERDKERET 98
RE + R+G +R+RE D D + + +K R
Sbjct: 805 EEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLL 864
Query: 99 DR-------------HTETDRE-RQKQKEREMERVRDREREKQKEM-------------- 130
+ H DR+ R K+++R+ ER R +++E+
Sbjct: 865 SQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQT 924
Query: 131 --------------GRERQTDRET-----DRERERQAERERETGRERKTEDRHRERER-E 170
G + DRET D E +++A+ +++ +++K +D ER E
Sbjct: 925 EILESSRMRAQDIIGHHQSEDRETSDRAHD-ENKKKAKIQKKPIKKKKEDDVGIERGNIE 983
Query: 171 RKRERERKRETKERERHTDMERERQR 196
E + K+ ++ +E++R++
Sbjct: 984 TTSEDGQVFSPKKGQKKKSIEKKRKK 1009
Score = 46.6 bits (109), Expect = 2e-05
Identities = 46/233 (19%), Positives = 82/233 (35%), Gaps = 22/233 (9%)
Query: 3 SKTEGRHTHTETETMDRQRERRRETDRER-------------DRAKESKTEDRHSERDRQ 49
SK + + + + +D+QR + +++ D A K ++++ +DR
Sbjct: 231 SKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRI 290
Query: 50 RDRERN---RERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDR 106
++ R+ R RD +R+REK+ + R RH+ + R
Sbjct: 291 EEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPR 350
Query: 107 ERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGR---ERKTED- 162
++ + R + + + R RE GR ER ++
Sbjct: 351 RKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSH 410
Query: 163 --RHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
RH RE R + K +ERE D R DR+ R+ RD
Sbjct: 411 DRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARD 463
Score = 43.1 bits (100), Expect = 2e-04
Identities = 52/241 (21%), Positives = 106/241 (43%), Gaps = 60/241 (24%)
Query: 18 DRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRE 77
+R + +R++ D E ++ TE+ S ++ R R+RE++ + +++T E E
Sbjct: 87 ERMKNKRQDVDTE---PQKRNTEESSSPVRKESSRGRHREKEDIKITKERTPESEEENVE 143
Query: 78 RERDRD------------RQRETERERDK-ERETDRHTETDRERQKQ----KEREMERVR 120
E +RD + E +R K +RE + + + E++++ KE E VR
Sbjct: 144 WETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVR 203
Query: 121 DR--------------EREKQKEMGRERQTDRET--------DRERERQAERERETGRER 158
+ +R+ + + DR+T D++R + + ++ G
Sbjct: 204 SKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRT 263
Query: 159 KT------ED-----RHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRE 207
+ ED +++E+ + + R E+ R+ K+R R D ER+R+ KRD+ R
Sbjct: 264 PSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGR--DFERQRE-----KRDKPRS 316
Query: 208 S 208
+
Sbjct: 317 T 317
Score = 40.4 bits (93), Expect = 0.001
Identities = 32/152 (21%), Positives = 68/152 (44%), Gaps = 11/152 (7%)
Query: 32 DRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERE 91
DR K EDR ER ++ R E +E+ D++ E+ E R R ++
Sbjct: 884 DRQGRWKEEDRKPER---KESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGH 940
Query: 92 RDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERE----RQ 147
E DR T +DR + K++ + + +++K+ ++G ER T + + ++
Sbjct: 941 HQSE---DRET-SDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKK 996
Query: 148 AERERETGRERKTEDRHRERERERKRERERKR 179
++++ ++RK + E ++ +K+
Sbjct: 997 GQKKKSIEKKRKKSKGDSDISDEEAAQQSKKK 1028
Score = 37.4 bits (85), Expect = 0.010
Identities = 28/149 (18%), Positives = 68/149 (45%), Gaps = 8/149 (5%)
Query: 5 TEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD--- 61
TE R + E DR+ ER+ + R ++ + K +R++ E +R R +D
Sbjct: 882 TEDRQGRWKEE--DRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIG 939
Query: 62 ---REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMER 118
E + +DR + +++ + + + + ++E D E T + Q ++ ++
Sbjct: 940 HHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQK 999
Query: 119 VRDREREKQKEMGRERQTDRETDRERERQ 147
+ E++++K G +D E ++ +++
Sbjct: 1000 KKSIEKKRKKSKGDSDISDEEAAQQSKKK 1028
Score = 34.7 bits (78), Expect = 0.062
Identities = 35/177 (19%), Positives = 72/177 (40%), Gaps = 15/177 (8%)
Query: 48 RQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRE 107
R +R R+R + + + D E +++ E ++E+ R R +E+E + T+
Sbjct: 76 RSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTP 135
Query: 108 RQKQKEREMERVRDRE----------REKQKEMGRERQTDRETDRERERQAERERETGRE 157
+++ E E RD E EM R++ E+E +RE ++
Sbjct: 136 ESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKK 195
Query: 158 RKTEDRHRER----ERERKRERERKRETKERERH-TDMERERQRETDRKRDRQRESE 209
+ + R + RK + KR++ + + +R+ + D+QR S+
Sbjct: 196 EVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSK 252
Score = 32.3 bits (72), Expect = 0.31
Identities = 25/103 (24%), Positives = 44/103 (42%), Gaps = 10/103 (9%)
Query: 109 QKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERE 168
++ ER +R+R + K++++ E Q +R E R+ + RHRE+E
Sbjct: 75 RRSPERPTGDLRERMKNKRQDVDTEPQ---------KRNTEESSSPVRKESSRGRHREKE 125
Query: 169 RERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERE 211
+ K +ER E++E + R+ D D E E
Sbjct: 126 -DIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLE 167
Score = 29.6 bits (65), Expect = 2.0
Identities = 28/120 (23%), Positives = 49/120 (40%), Gaps = 10/120 (8%)
Query: 96 RETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERER-ET 154
R +R T RER K K ++++ E QK E + + R R E+E +
Sbjct: 76 RSPERPTGDLRERMKNKRQDVDT------EPQKRNTEESSSPVRKESSRGRHREKEDIKI 129
Query: 155 GRERKTEDRHRERERERKRERERKRETK---ERERHTDMERERQRETDRKRDRQRESERE 211
+ER E E E R+ + E +M+R++ + K +++ +RE
Sbjct: 130 TKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKRE 189
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 188 bits (478), Expect = 3e-48
Identities = 93/202 (46%), Positives = 144/202 (71%), Gaps = 13/202 (6%)
Query: 17 MDRQRERRRETDR----ERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREG 72
M+RQRER+RETDR ER+R ++ + E++ +R R R+R+RERDR +REK+ +R+
Sbjct: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
Query: 73 ERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGR 132
ER R+R+R+R+ +RETER+R+++R+ +R +TDRER K ++RE +R DR RE+ ++ GR
Sbjct: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
Query: 133 ER--QTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDM 190
ER QT+RE DRERERQ +RERE R RER+RE RER+R E +ER++
Sbjct: 121 ERDKQTERERDRERERQRQRERE-------RQRQRERKRETDRERQRWAEREERKKERKK 173
Query: 191 ERERQRETDRKRDRQRESERER 212
ER+++R+ +K +++RE ++ +
Sbjct: 174 ERKKERKEKKKEEKRREDKKRK 195
Score = 166 bits (421), Expect = 1e-41
Identities = 83/186 (44%), Positives = 126/186 (67%), Gaps = 13/186 (6%)
Query: 8 RHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQ 67
R E +T R R+R+ RERDR + DR+++RER +ERDR R+RE++
Sbjct: 23 RQRERENQTERENRHRQRDRHRERDR-----------QTDREKERERQKERDRQRQRERE 71
Query: 68 TDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQ 127
T+RE ERQRER+R R+R+R+T+RERDK+R+ +R ETDR R++ ++ ER + ERE+
Sbjct: 72 TERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERD 131
Query: 128 KEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERH 187
+E R+RQ +RE R+RER+ E +RE R + E+R +ER++ERK+ER+ K+ KE +R
Sbjct: 132 RERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKK--KEEKRR 189
Query: 188 TDMERE 193
D +R+
Sbjct: 190 EDKKRK 195
Score = 155 bits (393), Expect = 2e-38
Identities = 83/161 (51%), Positives = 115/161 (71%), Gaps = 13/161 (8%)
Query: 59 DRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMER 118
+R RER+++TDR E +RER+R R+R+ +TERE ++ R+ DRH E DR+ ++KERE ++
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERE-NRHRQRDRHRERDRQTDREKERERQK 60
Query: 119 VRDREREKQKEMGRERQTDRETDRERERQAERE--RETGRER-KTEDRHRERERERKRER 175
RDR+R+ RER+T+RET+R+RERQ +RE R+T RER K DR R+RE +R RER
Sbjct: 61 ERDRQRQ------RERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRER 114
Query: 176 ERK---RETKERERHTDMERERQRETDRKRDRQRESERERD 213
RK K+ ER D ERERQR+ +R+R RQRE +RE D
Sbjct: 115 NRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETD 155
Score = 127 bits (318), Expect = 9e-30
Identities = 65/159 (40%), Positives = 105/159 (66%), Gaps = 13/159 (8%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHS-----ERDRQRDRERNR 56
+ +T+ + DRQR+R RET+RE +R +E + + ERD+ RDRER R
Sbjct: 47 DRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKR 106
Query: 57 ERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREM 116
E DR+RER ++ RE ++Q ERERDR+R+R+ +RER+++R+ +R ETDRERQ+ ERE
Sbjct: 107 ETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE- 165
Query: 117 ERVRDREREKQKEMGRERQTDRETDRERERQAERERETG 155
ER ++R++E++KE +E +E +R+ +++R+ G
Sbjct: 166 ERKKERKKERKKER-------KEKKKEEKRREDKKRKWG 197
Score = 50.1 bits (118), Expect = 1e-06
Identities = 25/55 (45%), Positives = 36/55 (65%), Gaps = 2/55 (3%)
Query: 19 RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGE 73
RQRER+RETDRER R E E+R ER ++R +ER ++ ++ RE + + GE
Sbjct: 146 RQRERKRETDRERQRWAE--REERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 180 bits (457), Expect = 7e-46
Identities = 87/219 (39%), Positives = 147/219 (67%), Gaps = 10/219 (4%)
Query: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDR 62
SK H E E +++ER+ R+R +E + E ER+R+R+RER RE++++R
Sbjct: 282 SKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKER 341
Query: 63 EREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDR 122
ERE++ DR+ +R +ER+RDRDR+R +R+RD+ER +DR+ + R R+K ++RE ER R+R
Sbjct: 342 ERERERDRDRDRTKERDRDRDRER--DRDRDRERSSDRNKDRSRSREKSRDRERERERER 399
Query: 123 EREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERK--------RE 174
ERE+++E RER+ +RE +RERER+ E++++ RE ED + R+ ERK +E
Sbjct: 400 EREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQE 459
Query: 175 RERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
R + E +ER++ + E+E +RE +R+R+ +E++R ++
Sbjct: 460 RLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKE 498
Score = 156 bits (395), Expect = 1e-38
Identities = 85/178 (47%), Positives = 123/178 (69%), Gaps = 12/178 (6%)
Query: 35 KESKTEDRHSERDRQRDRERNRERDRDR-EREKQTDREGERQRERERDRDRQRETERERD 93
+E K + E + RD + E ++ + E+E+Q + R+RERER+R+R+R ERER+
Sbjct: 270 EEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERR-ERERE 328
Query: 94 KERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERE 153
+ERE RER+K+KERE ER RDR+R++ KE R+R +R+ DR+RER ++R ++
Sbjct: 329 RERE--------REREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKD 380
Query: 154 TGRER-KTEDRHRERERERKRERERKRE-TKERERHTDMERERQRETDRKRDRQRESE 209
R R K+ DR RERERER+RERER+RE +ERER + ERER+RE D+KRDR+ + E
Sbjct: 381 RSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEE 438
Score = 154 bits (388), Expect = 7e-38
Identities = 97/265 (36%), Positives = 146/265 (55%), Gaps = 54/265 (20%)
Query: 2 ESKTEGRHTHTETET-MDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDR 60
E + R E E +++RER RE DR+RDR KE + DR ERDR RDRER+ +R++
Sbjct: 321 ERREREREREREREREKEKERERERERDRDRDRTKE-RDRDRDRERDRDRDRERSSDRNK 379
Query: 61 DREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREME--- 117
DR R ++ R+ ER+RERER+R+R+RE ERER++ERE +R E +RE+ K+++RE +
Sbjct: 380 DRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEED 439
Query: 118 ---------RVRDREREKQKEMG----RERQTDRETDRERERQAERERETGRE------- 157
++R++E Q+ + RER+ RE ++E ER+ ER RE +E
Sbjct: 440 AYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEF 499
Query: 158 --------------------RKTEDRHRER---ERERKRERERKRETKER---ERHTDME 191
++ DR +E ER+RKRE+E E ++R E H D +
Sbjct: 500 LEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPD 559
Query: 192 RERQR---ETDRKRDRQRESERERD 213
E QR E +R+R Q + E E +
Sbjct: 560 AELQRMEQEAERRRQPQIKQEPESE 584
Score = 139 bits (349), Expect = 2e-33
Identities = 96/304 (31%), Positives = 143/304 (47%), Gaps = 99/304 (32%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTE-DRHSERDRQRDRERNRERDR 60
E + R E E +R+RER RE +RE+++ +E + E DR +R ++RDR+R+RERDR
Sbjct: 308 ERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDR 367
Query: 61 DREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERV- 119
DR+RE+ +DR +R R RE+ RDR+RE ERER++ERE +R E +RER++++ERE ER
Sbjct: 368 DRDRERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREK 427
Query: 120 ---RDRE----------------REKQ------------KEMGRERQTDRETDRERERQA 148
RDRE REK+ +E + R+ ++E +RE ER+
Sbjct: 428 DKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRR 487
Query: 149 E----------------------------------RERETGRERKTEDRHRERER----- 169
E R+RE E DR RE+E
Sbjct: 488 EMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIR 547
Query: 170 ----------------------ERKRERERKRETKERERHTDMERERQRETDRKRDRQRE 207
ER+R+ + K+E + E E E ++E + KR+ E
Sbjct: 548 QRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEE-----EEEEKQEKEEKREEPME 602
Query: 208 SERE 211
E E
Sbjct: 603 EEEE 606
Score = 124 bits (312), Expect = 5e-29
Identities = 71/160 (44%), Positives = 104/160 (65%), Gaps = 22/160 (13%)
Query: 55 NRERDRDREREKQTDRE-GERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKE 113
+RE + R+ K+ + E G++++ER+ +RE ERER++ERE ++E
Sbjct: 278 SREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERE-------------RRE 324
Query: 114 REMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKR 173
RE ER R+REREK+KE RER+ DR+ DR +ER +R+RE R DR RER +R +
Sbjct: 325 REREREREREREKEKERERERERDRDRDRTKERDRDRDRERDR-----DRDRERSSDRNK 379
Query: 174 ERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
+R R RE K R+R + ERER+RE +R+R+R+RE ERER+
Sbjct: 380 DRSRSRE-KSRDR--ERERERERERERERERERERERERE 416
Score = 110 bits (276), Expect = 7e-25
Identities = 83/282 (29%), Positives = 130/282 (46%), Gaps = 86/282 (30%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKES-KTEDRHSERDRQRDRERNRERDR 60
E + E T +R R+R RE DR+RDR + S + +DR R++ RDRER RER+R
Sbjct: 340 ERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERER 399
Query: 61 DREREKQTDREGERQRERERDRDRQRETERERDK-------------------------- 94
+RERE++ +RE ER+RERER+R+R+RE +++RD+
Sbjct: 400 EREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQE 459
Query: 95 --------ERETDRHTETDRERQKQKEREM------------------------------ 116
ER+ R E + ER++++ REM
Sbjct: 460 RLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQ 519
Query: 117 ERVRDRE-----------REKQ------KEMGRERQTDRETDRER-ERQAERERETGRER 158
+R+RDRE REK+ + + E D + + +R E++AER R+ ++
Sbjct: 520 KRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQ 579
Query: 159 KTEDRHRERERERKRERERKRETKERERHTDMERERQRETDR 200
+ E E E E K+E+E KRE E ++ + T R
Sbjct: 580 EPES---EEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLR 618
Score = 40.4 bits (93), Expect = 0.001
Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
Query: 1 MESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDR 60
++ + R E + DR+RE + E + R R D +E R ++E R R
Sbjct: 518 LQKRLRDREKEMEADERDRKRE-KEELEEIRQRLLAEGHPDPDAELQRM-EQEAERRRQP 575
Query: 61 DREREKQTDREGERQRERERDRDRQRETERERDKE 95
++E +++ E E ++E+E R+ E E E +++
Sbjct: 576 QIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 175 bits (443), Expect = 3e-44
Identities = 91/202 (45%), Positives = 145/202 (71%), Gaps = 21/202 (10%)
Query: 19 RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRER 78
R+RER+RE +R+R RAKE RH E+DR+ +++R+R+R RDRER++ DR+ R+RER
Sbjct: 58 RERERQRERERQRKRAKE-----RHREKDREIEKDRDRQRKRDRERQRWRDRD--RKRER 110
Query: 79 ERDRDRQRETERERDKERETDRHTETDRERQKQKE------REMERVRDREREKQKEMGR 132
DRDR+ ETER+ ++ER+ DR E DRERQ+Q+E RE+E +DR+RE+ EMG
Sbjct: 111 WGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRER--EMGE 168
Query: 133 -ERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDME 191
ER DRE +R+++R+ R+R+ R+R+ EDR R+R+R+++RE++R RE R T +
Sbjct: 169 TERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRE-----RETGRD 223
Query: 192 RERQRETDRKRDRQRESERERD 213
R+++R+ +R+R++ R+ ++ D
Sbjct: 224 RDKERDRERQREKDRDRQKAID 245
Score = 173 bits (438), Expect = 1e-43
Identities = 93/196 (47%), Positives = 142/196 (72%), Gaps = 19/196 (9%)
Query: 18 DRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRE 77
+R+R+R RE R+R RAKE RH E+DR+ +++R+R+R RDRER++ DR +R+RE
Sbjct: 59 ERERQRERE--RQRKRAKE-----RHREKDREIEKDRDRQRKRDRERQRWRDR--DRKRE 109
Query: 78 RERDRDRQRETERERDKERETDRHTETDRERQKQ------KEREMERVRDREREKQKEMG 131
R DRDR+ ETER+ ++ER+ DR E DRERQ+Q K+RE+E +DR+RE +EMG
Sbjct: 110 RWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRE--REMG 167
Query: 132 R-ERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDM 190
ER DRE +R+++R+ R+R+ R+R+ EDR R+R+R+++RE++R RE +E R D
Sbjct: 168 ETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRE-RETGRDRDK 226
Query: 191 ERERQRETDRKRDRQR 206
ER+R+R+ ++ RDRQ+
Sbjct: 227 ERDRERQREKDRDRQK 242
Score = 155 bits (391), Expect = 3e-38
Identities = 82/180 (45%), Positives = 129/180 (71%), Gaps = 13/180 (7%)
Query: 4 KTEGRHTHTETET-MDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDR 62
+ + RH + E DR R+R+R+ +R+R R ++ K E R +RDR+ + ER ER+R R
Sbjct: 72 RAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRE-RWGDRDRETETERQEERERQR 130
Query: 63 EREKQTDREGERQRERERDRDRQRETERERDKER---ETDRHTETDRERQKQKEREMERV 119
+R+++ DRE +RQRE D+DR+ ETE++RD+ER ET+R+ DRER++QK+RE R
Sbjct: 131 DRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERY--RDRERERQKQRETRRD 188
Query: 120 RDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179
RDRER+++KE +R+ DR+ +ERE+ RERETGR+R D+ R+RER+R+++R+R++
Sbjct: 189 RDRERQREKE---DRERDRDRQKEREKDRYRERETGRDR---DKERDRERQREKDRDRQK 242
Score = 111 bits (278), Expect = 4e-25
Identities = 64/130 (49%), Positives = 88/130 (67%), Gaps = 16/130 (12%)
Query: 8 RHTHTET-ETMDRQRERRRETDRERDRAKE---SKTEDRHSERDRQRDRE-------RNR 56
R T TE E +RQR+R+RE DRER R +E K + +E+DR R+RE R+R
Sbjct: 116 RETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDR 175
Query: 57 ERDRDREREKQTDREGERQRE---RERDRDRQRETERERDKERET--DRHTETDRERQKQ 111
ER+R ++RE + DR+ ERQRE RERDRDRQ+E E++R +ERET DR E DRERQ++
Sbjct: 176 ERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQRE 235
Query: 112 KEREMERVRD 121
K+R+ ++ D
Sbjct: 236 KDRDRQKAID 245
Score = 103 bits (257), Expect = 1e-22
Identities = 56/131 (42%), Positives = 82/131 (62%), Gaps = 7/131 (5%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRER---NRER 58
+ +TE DR+RE+ RE R+R+ + +DR E ++ RDRER ER
Sbjct: 115 DRETETERQEERERQRDRKREKDRERQRQREIGID---KDREIETEKDRDREREMGETER 171
Query: 59 DRDREREKQTDREGERQRERERDRDRQ-RETERERDKERETDRHTETDRERQKQKEREME 117
RDRERE+Q RE R R+RER R+++ RE +R+R KERE DR+ E + R + KER+ E
Sbjct: 172 YRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRE 231
Query: 118 RVRDREREKQK 128
R R+++R++QK
Sbjct: 232 RQREKDRDRQK 242
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 139 bits (349), Expect = 2e-33
Identities = 73/221 (33%), Positives = 131/221 (59%), Gaps = 12/221 (5%)
Query: 3 SKTEGRHTHTETETMDRQ--RERRRETDRERDRA---KESKTEDRHSERDRQRDRERN-- 55
SK+ R ++++ R R R R+ DR R ++ K SK+ +R R R R++
Sbjct: 320 SKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKD 379
Query: 56 -RERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKER 114
RE+ +++ER K+ DRE ER+RE+ER+++++R ++RDKERE DR + +++R++++E+
Sbjct: 380 TREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREK 439
Query: 115 EMERVRDREREKQKEMGRERQTDRETDRERERQAERERET-GRERKTEDRHRERERERKR 173
E E+ RD+E+EK+++ +ER+ DR + + +R+ +++ T R R R RER+R
Sbjct: 440 EHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRR 499
Query: 174 ERERKRETKERERHTDMERERQRETDR---KRDRQRESERE 211
R R R T + + + R K+D++RE ER+
Sbjct: 500 RRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERD 540
Score = 130 bits (328), Expect = 6e-31
Identities = 74/223 (33%), Positives = 125/223 (56%), Gaps = 28/223 (12%)
Query: 19 RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRER 78
R+R + R RD+ K+++ + + ER +++DRE+ RER+++RE+EK+ + +R +ER
Sbjct: 362 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKER 421
Query: 79 ERDR--DRQRETERERDKERETDRHTETDRERQKQKEREMERVR--DREREKQKE----- 129
E+DR D++++ ERER+KE E DR E ++E+ K+KERE +R + D +R+K K+
Sbjct: 422 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 481
Query: 130 -----MGRERQTDRETDRERERQAERERETG-------------RERKTEDRHRERERER 171
R R + RE R R R + R T R R +D+ RE+ER+
Sbjct: 482 RSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDH 541
Query: 172 KRE-RERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
E RER+R T R+ D + + + E + +++E +E D
Sbjct: 542 ISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPD 584
Score = 128 bits (322), Expect = 3e-30
Identities = 62/199 (31%), Positives = 119/199 (59%), Gaps = 13/199 (6%)
Query: 21 RERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERER 80
R + R + + R K S+++ R +R R R+++R R + +++ RE + R R
Sbjct: 313 RSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSH 372
Query: 81 DRDRQRETE---RERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTD 137
RD++++T +E+++ +E DR E +RE++++KE+E + +DR++E++K +R+ D
Sbjct: 373 SRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREK----DREKD 428
Query: 138 RETDRERERQAERERETGRER-KTEDRHRERERERKRERERKRETKERER-----HTDME 191
+E DRERER+ E E++ +E+ K +D+ +ERE++R +E + KR+ ++ R +
Sbjct: 429 KEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR 488
Query: 192 RERQRETDRKRDRQRESER 210
R R +R+R R R S R
Sbjct: 489 RSRSSSRERRRRRSRSSSR 507
Score = 126 bits (316), Expect = 2e-29
Identities = 62/219 (28%), Positives = 128/219 (58%), Gaps = 11/219 (5%)
Query: 4 KTEGRH-THTETETMDRQRERRRETDRERDRAKES---KTEDRHSERDRQRD-----RER 54
+++ +H + + + RQ++RRR + R+K K+ R RD+++D +E+
Sbjct: 328 RSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEK 387
Query: 55 NRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKER 114
R +++DRE+E++ ++E E+++ER +++DR +E E++R+K++E DR E ++E +K +++
Sbjct: 388 ERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDK 447
Query: 115 EMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRE 174
E E+ +D+E+E++K+ +E R+ D+ + R R R ++ R R R R R
Sbjct: 448 EKEKEQDKEKEREKDRSKEIDEKRKKDK-KSRTPPRSYNASRRSRSSSRERRRRRSRSSS 506
Query: 175 RE-RKRETKERERHTDMERERQRETDRKRDRQRESERER 212
R R +T +R+ + + D+KR+++R+ ER
Sbjct: 507 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER 545
Score = 125 bits (315), Expect = 2e-29
Identities = 67/192 (34%), Positives = 113/192 (58%), Gaps = 15/192 (7%)
Query: 19 RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRER 78
+ ER+ R R+K + HS R R + + R+R +R R R+K R ++R
Sbjct: 299 KSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR 358
Query: 79 ERDRDRQRETERE--RDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQT 136
+ R+R++ R RDK ++T R ++ER K+K+RE ER R++EREK+KE G+ +
Sbjct: 359 SKSRERRKSRSRSHSRDKRKDT-REKIKEKERVKEKDREKEREREKEREKEKERGKNKDR 417
Query: 137 DRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQR 196
D+E +++RE+ E++RE RE+ E E++R +E+E K + KE+ER E++R +
Sbjct: 418 DKEREKDREKDKEKDREREREK-------EHEKDRDKEKE-KEQDKEKER----EKDRSK 465
Query: 197 ETDRKRDRQRES 208
E D KR + ++S
Sbjct: 466 EIDEKRKKDKKS 477
Score = 117 bits (294), Expect = 6e-27
Identities = 62/202 (30%), Positives = 112/202 (55%), Gaps = 13/202 (6%)
Query: 15 ETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGER 74
E M R RE + + + K+ +R R R R ++R + R K R
Sbjct: 277 EVMKRVREAQSFISAAIE-PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRK-------R 328
Query: 75 QRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRE---REKQKEMG 131
+ + R R R R++D+ R H + + R+++K R RD+ REK KE
Sbjct: 329 SQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKE 388
Query: 132 RERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDME 191
R ++ DRE +RERE++ E+E+E G+ K D+ RE++RE+ +E++R+RE +E+E D +
Sbjct: 389 RVKEKDREKEREREKEREKEKERGK-NKDRDKEREKDREKDKEKDRERE-REKEHEKDRD 446
Query: 192 RERQRETDRKRDRQRESERERD 213
+E+++E D++++R+++ +E D
Sbjct: 447 KEKEKEQDKEKEREKDRSKEID 468
Score = 72.0 bits (175), Expect = 3e-13
Identities = 38/147 (25%), Positives = 72/147 (48%), Gaps = 8/147 (5%)
Query: 66 KQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRERE 125
K+ + +R RE + E E + ER+ R R + + + R R R +
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR-RKRSQS 331
Query: 126 KQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERE 185
K + R R+ DR R + ++R RER+ + R R R+++++T+E+
Sbjct: 332 KHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERR-------KSRSRSHSRDKRKDTREKI 384
Query: 186 RHTDMERERQRETDRKRDRQRESERER 212
+ + +E+ RE +R+R+++RE E+ER
Sbjct: 385 KEKERVKEKDREKEREREKEREKEKER 411
Score = 57.0 bits (136), Expect = 1e-08
Identities = 36/142 (25%), Positives = 62/142 (43%), Gaps = 32/142 (22%)
Query: 104 TDRERQKQKEREMERVRDRER------EKQKEMGRERQTDRETDRERERQAERERETGRE 157
T + K+ E M+RVR+ + E + ER+ R R + + R
Sbjct: 267 TPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRR 326
Query: 158 RKTEDRHRERERERKRERER---------KRETKERERHTD-----------------ME 191
++++ +HR R R R R++ K+ +K RER E
Sbjct: 327 KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKE 386
Query: 192 RERQRETDRKRDRQRESERERD 213
+ER +E DR+++R+RE ERE++
Sbjct: 387 KERVKEKDREKEREREKEREKE 408
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 139 bits (349), Expect = 2e-33
Identities = 73/221 (33%), Positives = 131/221 (59%), Gaps = 12/221 (5%)
Query: 3 SKTEGRHTHTETETMDRQ--RERRRETDRERDRA---KESKTEDRHSERDRQRDRERN-- 55
SK+ R ++++ R R R R+ DR R ++ K SK+ +R R R R++
Sbjct: 204 SKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKD 263
Query: 56 -RERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKER 114
RE+ +++ER K+ DRE ER+RE+ER+++++R ++RDKERE DR + +++R++++E+
Sbjct: 264 TREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREK 323
Query: 115 EMERVRDREREKQKEMGRERQTDRETDRERERQAERERET-GRERKTEDRHRERERERKR 173
E E+ RD+E+EK+++ +ER+ DR + + +R+ +++ T R R R RER+R
Sbjct: 324 EHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRR 383
Query: 174 ERERKRETKERERHTDMERERQRETDR---KRDRQRESERE 211
R R R T + + + R K+D++RE ER+
Sbjct: 384 RRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERD 424
Score = 130 bits (328), Expect = 6e-31
Identities = 74/223 (33%), Positives = 125/223 (56%), Gaps = 28/223 (12%)
Query: 19 RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRER 78
R+R + R RD+ K+++ + + ER +++DRE+ RER+++RE+EK+ + +R +ER
Sbjct: 246 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKER 305
Query: 79 ERDR--DRQRETERERDKERETDRHTETDRERQKQKEREMERVR--DREREKQKE----- 129
E+DR D++++ ERER+KE E DR E ++E+ K+KERE +R + D +R+K K+
Sbjct: 306 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 365
Query: 130 -----MGRERQTDRETDRERERQAERERETG-------------RERKTEDRHRERERER 171
R R + RE R R R + R T R R +D+ RE+ER+
Sbjct: 366 RSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDH 425
Query: 172 KRE-RERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
E RER+R T R+ D + + + E + +++E +E D
Sbjct: 426 ISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPD 468
Score = 128 bits (322), Expect = 3e-30
Identities = 62/199 (31%), Positives = 119/199 (59%), Gaps = 13/199 (6%)
Query: 21 RERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERER 80
R + R + + R K S+++ R +R R R+++R R + +++ RE + R R
Sbjct: 197 RSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSH 256
Query: 81 DRDRQRETE---RERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTD 137
RD++++T +E+++ +E DR E +RE++++KE+E + +DR++E++K +R+ D
Sbjct: 257 SRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREK----DREKD 312
Query: 138 RETDRERERQAERERETGRER-KTEDRHRERERERKRERERKRETKERER-----HTDME 191
+E DRERER+ E E++ +E+ K +D+ +ERE++R +E + KR+ ++ R +
Sbjct: 313 KEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR 372
Query: 192 RERQRETDRKRDRQRESER 210
R R +R+R R R S R
Sbjct: 373 RSRSSSRERRRRRSRSSSR 391
Score = 126 bits (316), Expect = 2e-29
Identities = 62/219 (28%), Positives = 128/219 (58%), Gaps = 11/219 (5%)
Query: 4 KTEGRH-THTETETMDRQRERRRETDRERDRAKES---KTEDRHSERDRQRD-----RER 54
+++ +H + + + RQ++RRR + R+K K+ R RD+++D +E+
Sbjct: 212 RSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEK 271
Query: 55 NRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKER 114
R +++DRE+E++ ++E E+++ER +++DR +E E++R+K++E DR E ++E +K +++
Sbjct: 272 ERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDK 331
Query: 115 EMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRE 174
E E+ +D+E+E++K+ +E R+ D+ + R R R ++ R R R R R
Sbjct: 332 EKEKEQDKEKEREKDRSKEIDEKRKKDK-KSRTPPRSYNASRRSRSSSRERRRRRSRSSS 390
Query: 175 RE-RKRETKERERHTDMERERQRETDRKRDRQRESERER 212
R R +T +R+ + + D+KR+++R+ ER
Sbjct: 391 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER 429
Score = 125 bits (315), Expect = 2e-29
Identities = 67/192 (34%), Positives = 113/192 (58%), Gaps = 15/192 (7%)
Query: 19 RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRER 78
+ ER+ R R+K + HS R R + + R+R +R R R+K R ++R
Sbjct: 183 KSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR 242
Query: 79 ERDRDRQRETERE--RDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQT 136
+ R+R++ R RDK ++T R ++ER K+K+RE ER R++EREK+KE G+ +
Sbjct: 243 SKSRERRKSRSRSHSRDKRKDT-REKIKEKERVKEKDREKEREREKEREKEKERGKNKDR 301
Query: 137 DRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQR 196
D+E +++RE+ E++RE RE+ E E++R +E+E K + KE+ER E++R +
Sbjct: 302 DKEREKDREKDKEKDREREREK-------EHEKDRDKEKE-KEQDKEKER----EKDRSK 349
Query: 197 ETDRKRDRQRES 208
E D KR + ++S
Sbjct: 350 EIDEKRKKDKKS 361
Score = 117 bits (294), Expect = 6e-27
Identities = 62/202 (30%), Positives = 112/202 (55%), Gaps = 13/202 (6%)
Query: 15 ETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGER 74
E M R RE + + + K+ +R R R R ++R + R K R
Sbjct: 161 EVMKRVREAQSFISAAIE-PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRK-------R 212
Query: 75 QRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRE---REKQKEMG 131
+ + R R R R++D+ R H + + R+++K R RD+ REK KE
Sbjct: 213 SQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKE 272
Query: 132 RERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDME 191
R ++ DRE +RERE++ E+E+E G+ K D+ RE++RE+ +E++R+RE +E+E D +
Sbjct: 273 RVKEKDREKEREREKEREKEKERGK-NKDRDKEREKDREKDKEKDRERE-REKEHEKDRD 330
Query: 192 RERQRETDRKRDRQRESERERD 213
+E+++E D++++R+++ +E D
Sbjct: 331 KEKEKEQDKEKEREKDRSKEID 352
Score = 72.0 bits (175), Expect = 3e-13
Identities = 38/147 (25%), Positives = 72/147 (48%), Gaps = 8/147 (5%)
Query: 66 KQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRERE 125
K+ + +R RE + E E + ER+ R R + + + R R R +
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR-RKRSQS 215
Query: 126 KQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERE 185
K + R R+ DR R + ++R RER+ + R R R+++++T+E+
Sbjct: 216 KHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERR-------KSRSRSHSRDKRKDTREKI 268
Query: 186 RHTDMERERQRETDRKRDRQRESERER 212
+ + +E+ RE +R+R+++RE E+ER
Sbjct: 269 KEKERVKEKDREKEREREKEREKEKER 295
Score = 57.0 bits (136), Expect = 1e-08
Identities = 36/142 (25%), Positives = 62/142 (43%), Gaps = 32/142 (22%)
Query: 104 TDRERQKQKEREMERVRDRER------EKQKEMGRERQTDRETDRERERQAERERETGRE 157
T + K+ E M+RVR+ + E + ER+ R R + + R
Sbjct: 151 TPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRR 210
Query: 158 RKTEDRHRERERERKRERER---------KRETKERERHTD-----------------ME 191
++++ +HR R R R R++ K+ +K RER E
Sbjct: 211 KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKE 270
Query: 192 RERQRETDRKRDRQRESERERD 213
+ER +E DR+++R+RE ERE++
Sbjct: 271 KERVKEKDREKEREREKEREKE 292
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 134 bits (337), Expect = 6e-32
Identities = 72/194 (37%), Positives = 126/194 (64%), Gaps = 6/194 (3%)
Query: 19 RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRER 78
R+RER ET +E + +ES +R ER + R+R RE++R RER K+ +++GER++E
Sbjct: 39 REREREIETRKEGKKERES---ERKKERREREKRKREREKERKRERGKK-EKKGERKKEE 94
Query: 79 ERDRDRQRETERERDKERETDRHTE-TDRERQKQKEREMERVRDREREKQKEMGRERQTD 137
+ R+RE E + +E+E + E +R R ++ +E ER +R+RE++KE R+++ +
Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE-E 153
Query: 138 RETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRE 197
RE +RER+ + +RER+ E++ E + +ER+ +KRER RK KERER ER+++R+
Sbjct: 154 REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK 213
Query: 198 TDRKRDRQRESERE 211
+R ++R+ +R+
Sbjct: 214 KKEERKKERQKDRQ 227
Score = 131 bits (330), Expect = 4e-31
Identities = 75/200 (37%), Positives = 129/200 (64%), Gaps = 13/200 (6%)
Query: 21 RERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERER 80
RER RE + ++ KE ++E + R+R++ R+R RE++R RER K+ +++GER++E
Sbjct: 39 REREREIETRKEGKKERESERKKERREREK-RKREREKERKRERGKK-EKKGERKKEERE 96
Query: 81 DRDRQRETERERDKERETDRHTET-DRERQKQKEREMERVRDREREKQKEMGRERQTDRE 139
+ R+RE E + +E+E + E +R R ++ +E ER +R+RE++KE R+++ +RE
Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE-ERE 155
Query: 140 TDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRET- 198
+RER+ + +RER+ E++ E + +ER+ +KRER RK KERER ER+++R+
Sbjct: 156 KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKK 215
Query: 199 -----DRKRDRQ---RESER 210
+R++DRQ RE ER
Sbjct: 216 EERKKERQKDRQTNWREKER 235
Score = 126 bits (316), Expect = 2e-29
Identities = 68/213 (31%), Positives = 133/213 (62%), Gaps = 13/213 (6%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
E + E R + +R++ERR R+R+R KE K E E+ +R +E + R
Sbjct: 42 EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR 101
Query: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121
RE+E + E E+++++E+ ++R R ++ +++ER+ +R E +ER+++KE ER ++
Sbjct: 102 REKENKEGEEKEKRKKKEK-KERGRTSKEGKERERKEERKREERKERERKKE---EREKE 157
Query: 122 REREKQKEMGRERQTDRETDR-ERERQAERERETGRERKTEDRHRERERERKRERERKRE 180
RER+++K+ R++ ++E +R E+ER+ ++RE R+ + ++R R+ RERK+ER++K E
Sbjct: 158 RERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEE 217
Query: 181 TKERERHTDMERERQRETD-RKRDRQRESERER 212
K+ ER++ R+T+ R+++R + +ER
Sbjct: 218 RKK-------ERQKDRQTNWREKERGKRERKER 243
Score = 122 bits (306), Expect = 2e-28
Identities = 67/172 (38%), Positives = 116/172 (67%), Gaps = 11/172 (6%)
Query: 50 RDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQ 109
R+RER E ++ ++E++++R+ ER+ +R R+R++E +RER K+ + + +RER+
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
Query: 110 KQK-EREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETG--RERKTEDRHRE 166
K++ E+E + ++E+ K+KE +T +E +ERER+ ER+RE RERK E+R +E
Sbjct: 99 KRRREKENKEGEEKEKRKKKEKKERGRTSKE-GKERERKEERKREERKERERKKEEREKE 157
Query: 167 RERERKRERERKR------ETKERERHTDMERERQRETDRKRDRQRESERER 212
RER+ +++RERK+ E KE+ER +RER R+ +RK++R+R+ RER
Sbjct: 158 RERKERKKRERKQVGEKEEERKEKERKERKKRERNRK-ERKKERERKERRER 208
Score = 97.4 bits (241), Expect = 8e-21
Identities = 56/155 (36%), Positives = 98/155 (63%), Gaps = 17/155 (10%)
Query: 60 RDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERV 119
R+RERE +T +EG+++RE ER ++R+ +R+R++E+E R ++ ++K+ E ER
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERER- 97
Query: 120 RDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179
+ R REK+ + G E++ +R+ + ++E GR K +ERERK ER+R+
Sbjct: 98 KKRRREKENKEGEEKE---------KRKKKEKKERGRTSK-----EGKERERKEERKRE- 142
Query: 180 ETKERER-HTDMERERQRETDRKRDRQRESERERD 213
E KERER + E+ER+R+ +KR+R++ E+E +
Sbjct: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEEE 177
Score = 43.5 bits (101), Expect = 1e-04
Identities = 27/63 (42%), Positives = 40/63 (63%), Gaps = 9/63 (14%)
Query: 159 KTEDRHRERE----RERKRER--ERKRETKERE---RHTDMERERQRETDRKRDRQRESE 209
++E R RERE +E K+ER ERK+E +ERE R + ER+R+R K+ +++ E
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 210 RER 212
RER
Sbjct: 95 RER 97
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 134 bits (336), Expect = 7e-32
Identities = 67/204 (32%), Positives = 131/204 (64%), Gaps = 6/204 (2%)
Query: 11 HTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDR 70
+TE + + + T RE +R KE + ++ R R+R++ER RER + +E++K+ R
Sbjct: 14 NTELQMVSCSHISKPCTQRESERKKERREREK---RKREREKERKRERGK-KEKKKRKKR 69
Query: 71 EGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDR-EREKQKE 129
E ++RER+R ++R+++ + R+KER + + RER+++ RE ++ ++R ERE++ +
Sbjct: 70 ERGKERERKR-KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENK 128
Query: 130 MGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTD 189
RER+ + ++R ++ +RE+E G+ + + ++ ERE+KRER RK KERER
Sbjct: 129 QRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER 188
Query: 190 MERERQRETDRKRDRQRESERERD 213
ER+++R+ +R++ ++R+ +R+ D
Sbjct: 189 RERKKERKKERRKKKERKKDRKTD 212
Score = 131 bits (330), Expect = 4e-31
Identities = 70/195 (35%), Positives = 130/195 (66%), Gaps = 14/195 (7%)
Query: 18 DRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRE 77
+R++ERR R+R+R KE K E E+ +++ RER +ER+R R+ +RE +R+
Sbjct: 35 ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRK-----EREKQRKER 89
Query: 78 RERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTD 137
RE++R ++++ +++R++++ R + +ER K++ERE ++ R+R+R+K+++ R ++
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKER-KERERENKQRRERKRKKRRKKKRRKERK 148
Query: 138 RETDR-ERERQAERERETGRERKTEDRHRER--ERERKRERERKRETKERERHTDMERER 194
RE +R +RER+ ++ ++ RE+K E +ER ERERK RERK+E K+ R +++
Sbjct: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERR-----KKK 203
Query: 195 QRETDRKRDRQRESE 209
+R+ DRK DRQ +S+
Sbjct: 204 ERKKDRKTDRQTDSQ 218
Score = 129 bits (325), Expect = 1e-30
Identities = 65/198 (32%), Positives = 134/198 (67%), Gaps = 11/198 (5%)
Query: 10 THTETETMDRQRER-RRETDRERDRAKESKTEDRHSERDRQRDRERNRER-DRDREREKQ 67
T E+E +RER +R+ +RE++R +E +++ + R+R +ER R+R +R+++R+++
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
Query: 68 TDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQ 127
++E ++++ ++ R+R++ RER K++E +RER+ ++ RE +R + R+++++
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKE-----RKERERENKQRRERKRKKRRKKKRR 144
Query: 128 KEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERH 187
KE RE++ + +R+R+++ + ERE RER ++R +ERER+ +RER+++R ++ER
Sbjct: 145 KERKREKERGKR-ERKRKKRKKEEREKKRERNRKERKKERERKERRERKKER---KKERR 200
Query: 188 TDMERERQRETDRKRDRQ 205
ER++ R+TDR+ D Q
Sbjct: 201 KKKERKKDRKTDRQTDSQ 218
Score = 106 bits (264), Expect = 2e-23
Identities = 68/205 (33%), Positives = 118/205 (57%), Gaps = 34/205 (16%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRET---------------DRERDRAKESKTEDRHSER 46
ES+ + E +R++ER+RE +RER R ER
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKR----------KER 82
Query: 47 DRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDR 106
++QR R +ER + ++ +K+ +R+ +RER++ ++R +E ERE + RE R +
Sbjct: 83 EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER-KERERENKQRRERKRKKRRKK 141
Query: 107 ERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRE 166
+R+K+++RE ER + RER+++K ER+ RE +R +ER+ ERER+ RERK +E
Sbjct: 142 KRRKERKREKERGK-RERKRKKRKKEEREKKRERNR-KERKKERERKERRERK-----KE 194
Query: 167 RERERKRERERKRETKERERHTDME 191
R++ER++++ERK++ K +R TD +
Sbjct: 195 RKKERRKKKERKKDRK-TDRQTDSQ 218
Score = 100 bits (249), Expect = 9e-22
Identities = 59/167 (35%), Positives = 107/167 (64%), Gaps = 9/167 (5%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHS----ERDRQRDR-ERNR 56
+ + G+ + + ++QR+ RRE +R R R KE K +R ER ++++R ER R
Sbjct: 67 KKRERGKERERKRKEREKQRKERREKER-RKRKKEKKKRERKQRGRRERKKKKERKERER 125
Query: 57 ERDRDREREKQTDREGERQRERERDRDR-QRETERERDKERETDRHTETDR-ERQKQKER 114
E + RER+++ R+ +R++ER+R+++R +RE +R++ K+ E ++ E +R ER+K++ER
Sbjct: 126 ENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERER 185
Query: 115 EMERVRDREREKQKEMGRERQTDRETDRERERQAERE-RETGRERKT 160
+ R R +ER+K++ +ER+ DR+TDR+ + Q R RE+ R T
Sbjct: 186 KERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVT 232
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 127 bits (318), Expect = 9e-30
Identities = 74/219 (33%), Positives = 120/219 (54%), Gaps = 8/219 (3%)
Query: 1 MESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDR 60
+E + E + E + +++R R R DR +R + S++ +RH R R RDR+ +R RDR
Sbjct: 295 LEREKERQRLEREAKEREKERRRSRSIDRGLER-RRSRSRERHRSRSRSRDRKGDR-RDR 352
Query: 61 DREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKE-REMERV 119
DREREK+ +R R R+ +++R +RE ERER +ER ++ + + E +K KE ++ R
Sbjct: 353 DREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRH 412
Query: 120 RDREREKQKEMGRERQTDRE---TDRERERQA-ERERETGRERKTEDRHRERERERKRER 175
RD +R+ +KE R RE R R R A +R R +E+ ++ ++ +E+ KR R
Sbjct: 413 RDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSR 472
Query: 176 ERKR-ETKERERHTDMERERQRETDRKRDRQRESERERD 213
+ T E+ E +E RKR R +E +RD
Sbjct: 473 SGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRD 511
Score = 117 bits (292), Expect = 9e-27
Identities = 67/215 (31%), Positives = 114/215 (53%), Gaps = 17/215 (7%)
Query: 15 ETMDRQRERRRETDRERDRA-----KESKTEDRHSER------DRQRDRERNRER----D 59
E +DR ERRR R + + S++ H E DR+ +RE+ R+R
Sbjct: 249 EEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREA 308
Query: 60 RDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERV 119
++RE+E++ R +R ER R R R+R R R ++R+ DR + DRER+K+ ER R
Sbjct: 309 KEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRR-DRDREREKENERGRRRD 367
Query: 120 RDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179
RD ++E+ E +ER+ RE +E+ + E E + +E K + RHR+ +R+ K+E++ R
Sbjct: 368 RDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSR 427
Query: 180 ETKERERHTDMERERQR-ETDRKRDRQRESERERD 213
+H R R + R R +++ S+ + +
Sbjct: 428 SRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNE 462
Score = 117 bits (292), Expect = 9e-27
Identities = 65/218 (29%), Positives = 115/218 (52%), Gaps = 8/218 (3%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
E + E R + + ++R+R R RE R R R+++ K + R +R+R+++ ER R RDRD
Sbjct: 310 EREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRD 369
Query: 62 REREKQTDREGERQRERERDRDRQR--ETERERDKERETDRHTETDRERQKQKEREMERV 119
++E+ +RE ER+R RER ++++ E E ++ KE + DR D+ R +KE++ R
Sbjct: 370 YDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDK-RDSKKEKKHSRS 428
Query: 120 RDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179
R RER+ + R R +E+ ++ + E+ + R + R E+ +KR
Sbjct: 429 RSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKR 488
Query: 180 E-----TKERERHTDMERERQRETDRKRDRQRESERER 212
E K R+R ER +R+ +D+ + +R R
Sbjct: 489 EHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRR 526
Score = 98.6 bits (244), Expect = 3e-21
Identities = 55/212 (25%), Positives = 111/212 (52%), Gaps = 9/212 (4%)
Query: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRAKES---KTEDRHSERDRQRDRERNRERD 59
S++ RH + + + DR+ +RR DR+R+R KE+ + DR +++R +RE+ RER
Sbjct: 330 SRSRERH-RSRSRSRDRKGDRR---DRDREREKENERGRRRDRDYDKERGNEREKERERS 385
Query: 60 RDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERV 119
R+R +E+++ E E ++ +E D+D +R + +RD ++E RER+ +
Sbjct: 386 RERSKEQRSRGEVEEKKHKE-DKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNA 444
Query: 120 RDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179
R R + KE + + + + + ++ + T K++ R +E+ R+R R +
Sbjct: 445 GKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSK 504
Query: 180 ETKERERHTDMERERQRETDRKRDRQRESERE 211
E + H+D +++ + DR+R + E E +
Sbjct: 505 ERSHKRDHSD-SKDQSDKHDRRRSQSIEQESQ 535
Score = 97.8 bits (242), Expect = 6e-21
Identities = 61/194 (31%), Positives = 98/194 (50%), Gaps = 17/194 (8%)
Query: 35 KESKTEDRHSERDRQR-----DRERNRERDRDREREKQTDREGERQRERERDRDRQRETE 89
++ KT R ++D + DR R R R R R R R R R+ +
Sbjct: 231 QQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSS 290
Query: 90 RERDKERETDRHTETDRERQKQKER----------EMERVRDREREKQKEMGRERQTDRE 139
+R+ ERE +R ++++KER E R R RER + + R+R+ DR
Sbjct: 291 FDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRR 350
Query: 140 TDRERERQAERERETGRERK-TEDRHRERERERKRERERKRETKERERHTDMERERQRET 198
DR+RER+ E ER R+R ++R ERE+ER+R RER +E + R + + + ++
Sbjct: 351 -DRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDD 409
Query: 199 DRKRDRQRESERER 212
R RD +R+S++E+
Sbjct: 410 RRHRDDKRDSKKEK 423
Score = 74.7 bits (182), Expect = 5e-14
Identities = 45/173 (26%), Positives = 88/173 (50%), Gaps = 11/173 (6%)
Query: 18 DRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRE 77
+R++ER R +R +++ + E++ + D +D R+R+ RD ++EK+ R R+R
Sbjct: 377 EREKERERSRERSKEQRSRGEVEEKKHKED--KDDRRHRDDKRDSKKEKKHSRSRSRER- 433
Query: 78 RERDRDRQR---ETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRER 134
+ R R R R + R R KE+ + +H +E+ ++ R + R EK K+ RE
Sbjct: 434 KHRSRSRSRNAGKRSRSRSKEK-SSKHKNESKEKSNKRSRSGSQGRTDSVEKSKK--REH 490
Query: 135 QTDRETDRERERQAER--ERETGRERKTEDRHRERERERKRERERKRETKERE 185
+E R+R R ER +R+ + D+H R + + ++++ K ++
Sbjct: 491 SPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKD 543
Score = 72.8 bits (177), Expect = 2e-13
Identities = 43/137 (31%), Positives = 72/137 (52%), Gaps = 3/137 (2%)
Query: 79 ERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDR 138
+++ D+Q +T + K+ + E DR ++++ R R R ++ R +
Sbjct: 226 QKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREG 285
Query: 139 ETDRERERQAERERETGR-ERKTEDRHRERERERKRERE-RKRETKERERHTDMERERQR 196
+R+ ERE+E R ER+ ++R +ER R R +R +R ++ RERH R R R
Sbjct: 286 HGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDR 345
Query: 197 ETDRK-RDRQRESERER 212
+ DR+ RDR+RE E ER
Sbjct: 346 KGDRRDRDREREKENER 362
Score = 65.9 bits (159), Expect = 3e-11
Identities = 39/169 (23%), Positives = 85/169 (50%), Gaps = 10/169 (5%)
Query: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDR 62
S+ + + E +++ + ++ R RD ++SK E +HS R R R+R ++R R R R
Sbjct: 385 SRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHS-RSRSRER-KHRSRSRSR 442
Query: 63 EREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDR-ERQKQKEREMERVRD 121
K++ R R +E+ + E++ + +K + TD E+ K++E + +
Sbjct: 443 NAGKRS-----RSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKS 497
Query: 122 REREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERE 170
R+R + KE R + D +++ + +R R E++++++ + + E
Sbjct: 498 RKRSRSKE--RSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDE 544
Score = 62.8 bits (151), Expect = 2e-10
Identities = 34/127 (26%), Positives = 63/127 (49%), Gaps = 2/127 (1%)
Query: 2 ESKTEGRHTHTET-ETMDRQRERRRET-DRERDRAKESKTEDRHSERDRQRDRERNRERD 59
+SK E +H+ + + E R R R R R R R+KE ++ ++ +++ R R+ +
Sbjct: 418 DSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQG 477
Query: 60 RDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERV 119
R EK RE +E+ R R R +E +RD D+ + DR R + E+E +
Sbjct: 478 RTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEK 537
Query: 120 RDREREK 126
+ + +++
Sbjct: 538 QHKNKDE 544
Score = 60.8 bits (146), Expect = 8e-10
Identities = 38/120 (31%), Positives = 55/120 (45%), Gaps = 2/120 (1%)
Query: 95 ERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERET 154
++ D+ +T + K+ +E DR E+++ R R R RE
Sbjct: 226 QKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHRE- 284
Query: 155 GRERKTEDRHRERERERKR-ERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
G + DR ERE+ER+R ERE K KER R ++R +R R R+R R R RD
Sbjct: 285 GHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRD 344
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 113 bits (283), Expect = 1e-25
Identities = 64/211 (30%), Positives = 118/211 (55%), Gaps = 8/211 (3%)
Query: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRE 63
K E + E + ++Q++R R + R + +E + E + R++Q RE+ ER +
Sbjct: 280 KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQL 339
Query: 64 REKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRE 123
R +Q +R ++ R + + R+++ RE+++ER R + RE+Q ++E+++ R +
Sbjct: 340 RREQEERREQQLRREQEEERREQQLRREQEEER---REQQLRREQQLRREQQLRREQQLR 396
Query: 124 REKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKE 183
RE+Q + RE+Q RE RE+Q RE++ RE++ E+RH ++ + +RE+ KRE +E
Sbjct: 397 REQQ--LRREQQLRREQQLRREQQLRREQQLRREQE-EERHEQKHEQERREQRLKREQEE 453
Query: 184 RERHTDMERERQRETDRKRDRQ--RESERER 212
R E E +R +R +Q R+ E ER
Sbjct: 454 RRDWLKREEETERHEQERRKQQLKRDQEEER 484
Score = 113 bits (283), Expect = 1e-25
Identities = 67/211 (31%), Positives = 118/211 (55%), Gaps = 8/211 (3%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
E + E + + + + R+++ RR+ + ER +E + E + ++ RE+ R+++
Sbjct: 285 ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQE 344
Query: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121
RE+Q RE Q E R++ +RE E ER +E++ R + RE+Q ++E+++ R +
Sbjct: 345 ERREQQLRRE---QEEERREQQLRREQEEER-REQQLRREQQLRREQQLRREQQLRREQQ 400
Query: 122 REREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRET 181
RE+Q + RE+Q RE RE+Q RE+E R + ++ R RE+ KRE+E +R+
Sbjct: 401 LRREQQ--LRREQQLRREQQLRREQQLRREQEEERHEQKHEQER-REQRLKREQEERRDW 457
Query: 182 KERERHTDMERERQRETDRKRDRQRESERER 212
+RE T+ + +R+ KRD Q E RER
Sbjct: 458 LKREEETERHEQERRKQQLKRD-QEEERRER 487
Score = 110 bits (276), Expect = 7e-25
Identities = 69/220 (31%), Positives = 121/220 (55%), Gaps = 13/220 (5%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDR--QRDRE---RNR 56
E + + H E D ++ RRRE R + +E K + R +DR Q + E R R
Sbjct: 190 EEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKR 249
Query: 57 ERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREM 116
E +E EK + E +RQRE + + ++ R+ ER+ E +R E ++++ ++E+++
Sbjct: 250 ETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ---ELRRERQEEEQQQQRLRREQQL 306
Query: 117 ERVRDREREKQKEMGRERQTDRETDRER-ERQAERERETGRE----RKTEDRHRERERER 171
R ++ ER +Q+E RE+Q RE ER E+Q RE+E RE R+ E+ RE++ R
Sbjct: 307 RRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRR 366
Query: 172 KRERERKRETKERERHTDMERERQRETDRKRDRQRESERE 211
++E ER+ + RE+ E++ +RE +R++Q E++
Sbjct: 367 EQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 406
Score = 110 bits (276), Expect = 7e-25
Identities = 62/226 (27%), Positives = 120/226 (53%), Gaps = 15/226 (6%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
E + + + E + +Q E RRE ER R ++ + E + R++Q RE+ R++
Sbjct: 292 EEEQQQQRLRREQQLRRKQEEERREQQEER-REQQERREQQEERREQQLRREQEERREQQ 350
Query: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121
RE++ +R ++ R + + R+++ RE+ RE E R++Q RE + R+
Sbjct: 351 LRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 410
Query: 122 REREKQKEMGRERQTDRETDRER----------ERQAERERETGRE--RKTEDRHRERER 169
++ +++++ RE+Q RE + ER E++ +RE+E R+ ++ E+ R +
Sbjct: 411 QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE 470
Query: 170 ERKRERERKRETKERERHTDMERERQRETDRKRDRQ--RESERERD 213
RK++ +R +E + RER +E E +RE +R++Q RE E R+
Sbjct: 471 RRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERRE 516
Score = 108 bits (270), Expect = 3e-24
Identities = 66/218 (30%), Positives = 120/218 (55%), Gaps = 11/218 (5%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
E + E + E + Q+E RRE R++ + + + R + + +R+++ RE++ +
Sbjct: 312 EERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Query: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121
R RE+Q RE + +RE++ R++Q E++ +E++ R + RE+Q ++E+++ R ++
Sbjct: 372 R-REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQE 430
Query: 122 REREKQK-EMGRERQTDRETDRERERQAERERETGR---ERKTEDRHRERERER-----K 172
ER +QK E R Q + ER +RE ET R ER+ + R++E ER K
Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK 490
Query: 173 RERERKRETKERERHTDMERERQRETDRKRDRQRESER 210
E E +RE +ER R + RE++ +++ RQ E ER
Sbjct: 491 LEEEERREQQER-REQQLRREQEERREQRLKRQEEEER 527
Score = 107 bits (267), Expect = 8e-24
Identities = 60/203 (29%), Positives = 116/203 (57%), Gaps = 5/203 (2%)
Query: 13 ETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREG 72
E + + + +R+RE E ++ + K E + R+RQ + ++ + R+++ ++ + E
Sbjct: 257 EEKLQEEEPQRQRELQEEEEQLR--KLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314
Query: 73 ERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGR 132
Q+E R++ +RE + ER +E++ R E RE+Q ++E+E ER + R +Q+E R
Sbjct: 315 REQQEERREQQERREQQEER-REQQLRREQEERREQQLRREQEEERREQQLRREQEEERR 373
Query: 133 ERQTDRETDRERERQAERERETGRERK-TEDRHRERERERKRERERKRETKERERHTDME 191
E+Q RE RE+Q RE++ RE++ ++ RE++ +RE++ +RE + R +
Sbjct: 374 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEER 433
Query: 192 RERQRETDRKRDR-QRESERERD 213
E++ E +R+ R +RE E RD
Sbjct: 434 HEQKHEQERREQRLKREQEERRD 456
Score = 105 bits (262), Expect = 3e-23
Identities = 65/234 (27%), Positives = 121/234 (51%), Gaps = 23/234 (9%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
E + E R E +R+ ++ R E R ++ + E R++Q RE+ R++
Sbjct: 329 EQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQ 388
Query: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQK-QKEREMERVR 120
RE+Q RE + +RE++ R++Q E++ +E++ R E +R QK ++ER +R++
Sbjct: 389 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK 448
Query: 121 DREREKQKEMGRERQTDRETDRERERQAERERETGR----------ERKTEDRHRE---- 166
+ E++ + RE +T+R R++Q +R++E R ER+ + RE
Sbjct: 449 REQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLR 508
Query: 167 RERERKRERERKRETKER--------ERHTDMERERQRETDRKRDRQRESERER 212
RE+E +RE+ KR+ +E E+ E+E +RE KR+ ++ E+ER
Sbjct: 509 REQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562
Score = 105 bits (261), Expect = 4e-23
Identities = 75/239 (31%), Positives = 119/239 (49%), Gaps = 33/239 (13%)
Query: 4 KTEGRHTHTETETMDRQRERRRETDRERD---RAKESKTEDRHSERDRQRDRERNRERDR 60
+ E E + Q E RRE R+ R ++ ++ R++Q RE+ R++
Sbjct: 352 RREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 411
Query: 61 DREREKQTDREGERQRERERDRDRQ------------RETERERD---KERETDRHTETD 105
RE+Q RE + +RE+E +R Q RE E RD +E ET+RH +
Sbjct: 412 QLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQER 471
Query: 106 RERQKQKEREMER------VRDREREKQKEMGRERQTDRETDRERE----RQAERERETG 155
R++Q ++++E ER + + ER +Q+E RE+Q RE + RE RQ E ER
Sbjct: 472 RKQQLKRDQEEERRERWLKLEEEERREQQER-REQQLRREQEERREQRLKRQEEEERLQQ 530
Query: 156 RERKTEDRHRERERER----KRERERKRETKERERHTDMERERQRETDRKRDRQRESER 210
R R + RE+E R KRE E++ E + RE+ E+E +R+ KR+ +R +R
Sbjct: 531 RLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQR 589
Score = 104 bits (260), Expect = 5e-23
Identities = 59/221 (26%), Positives = 119/221 (53%), Gaps = 14/221 (6%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSE---RDRQRDRERNRER 58
E + E + + E ++Q R +E +R + + + E+R + R++Q RE+ R
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391
Query: 59 DRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMER 118
++ RE+Q RE + +RE++ R++Q E++ +E+E +RH E++ ++ER +R
Sbjct: 392 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH-----EQKHEQERREQR 446
Query: 119 VRDREREKQKEMGRERQTDRETDRERERQAERERETGRER---KTEDRHRERERERKRER 175
++ + E++ + RE +T+R R++Q +R++E R K E+ R ++ER+ ++
Sbjct: 447 LKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506
Query: 176 ERKRETKERERHTDMERERQRETDRKRDRQ---RESERERD 213
R+ + + RE+ + E +R R R Q RE E R+
Sbjct: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE 547
Score = 103 bits (257), Expect = 1e-22
Identities = 74/242 (30%), Positives = 130/242 (53%), Gaps = 32/242 (13%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKE-SKTEDRHSERDRQR-DRERNRERD 59
+ + E R E E R+R++R+E +RE +E S+ ++R +RDRQR D E R+R
Sbjct: 119 QRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQ 178
Query: 60 RDREREKQT------------------DREGERQRE----RERDRDRQRETERERDKERE 97
+ERE++ D E R+RE R + R+ +++ RER
Sbjct: 179 EWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVF 238
Query: 98 TDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRE---RERQAERERET 154
+ + R+R+ +E E++++ E ++Q+E+ E + R+ +R+ RERQ E E++
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ-EEEQQQ 297
Query: 155 GRERKTEDRHRERERERKRERERKRETKERERHTDMERERQ--RETDRKRDRQ--RESER 210
R R+ + R++E ER+ ++E +RE +ER + RE+Q RE + +R++Q RE E
Sbjct: 298 QRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE 357
Query: 211 ER 212
ER
Sbjct: 358 ER 359
Score = 102 bits (255), Expect = 2e-22
Identities = 62/222 (27%), Positives = 119/222 (53%), Gaps = 11/222 (4%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERD---RAKESKTEDRHSERDRQRDRERNRER 58
E + + E E R+++ RRE R+ R ++ ++ R++Q RE+ R
Sbjct: 356 EEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 415
Query: 59 DRDREREKQTDREGERQRERERDRDRQRETERERDKERETD---RHTETDRERQKQKERE 115
++ RE+Q RE E +R ++ +RE +R++E D R ET+R Q++++++
Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475
Query: 116 MERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRE---RKTEDRHRERERERK 172
++R ++ ER +++ + E + RE RE+Q RE+E RE ++ E+ R ++R R
Sbjct: 476 LKRDQEEER-RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRS 534
Query: 173 RERERKRETKERERHTDMERERQRETDRKRDR-QRESERERD 213
++ R+ + + RE+ E E++ E +R+ R +RE E RD
Sbjct: 535 EQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576
Score = 101 bits (252), Expect = 4e-22
Identities = 64/215 (29%), Positives = 109/215 (50%), Gaps = 6/215 (2%)
Query: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRE---RNRERDR 60
+ E + E E + ++ E+ +RE+ R +E + + R + +Q + + RE+ R
Sbjct: 983 RQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRR 1042
Query: 61 DREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVR 120
+ERE+Q E E Q+E E+ +RET R ++ ER+ + E +E ++ E E+ R
Sbjct: 1043 LQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102
Query: 121 DREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRE 180
+ERE+Q E Q + E ER+ R +E R+ + E+ ++ E + RE KR
Sbjct: 1103 RQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162
Query: 181 TKERERHTDMERERQRETD---RKRDRQRESERER 212
+E ER E E Q+E + R+ +R ERER
Sbjct: 1163 RQELERQYREEEELQQEEEQLLREEQEKRRQERER 1197
Score = 100 bits (250), Expect = 7e-22
Identities = 62/204 (30%), Positives = 105/204 (51%), Gaps = 9/204 (4%)
Query: 13 ETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREG 72
E + + +RE+RR +RER K+ K + + + + +R R+ EREK+ E
Sbjct: 940 EEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQ-----EREKKYREEE 994
Query: 73 ERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGR 132
E Q+E E+ +RE R ++ ER+ + E +E ++ E E+ R +ERE+Q
Sbjct: 995 ELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEE 1054
Query: 133 ERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMER 192
E Q + E ER+ R +E R+ + E+ ++ E + RE KR +ERER E
Sbjct: 1055 ELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEE 1114
Query: 193 ERQRETDR----KRDRQRESERER 212
E Q+E ++ +R+++R E ER
Sbjct: 1115 ELQQEEEQLLREEREKRRRQELER 1138
Score = 100 bits (250), Expect = 7e-22
Identities = 60/220 (27%), Positives = 117/220 (53%), Gaps = 22/220 (10%)
Query: 13 ETETMDRQRERRRETDRERDRAKESKT---------EDRHSERDRQRDRERNRERDRDRE 63
E + + +RE+RR + ER K+ + E+R R ++R+R+ E + +E
Sbjct: 1000 EEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQE 1059
Query: 64 REKQTDREGERQRERERDRDRQRETERERDKER----ETDRHTETDRERQKQKEREMERV 119
E+ E E +R +E +R ++E E ++++E+ E ++ +RERQ ++E E+++
Sbjct: 1060 EEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE 1119
Query: 120 ------RDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKR 173
+RE+ +++E+ R+ + + E +E E+ E E R ++ E ++RE E ++
Sbjct: 1120 EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE 1179
Query: 174 ERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
E + RE +E+ R ERERQ + + RQ+ +R RD
Sbjct: 1180 EEQLLREEQEKRR---QERERQYREEEELQRQKRKQRYRD 1216
Score = 100 bits (249), Expect = 9e-22
Identities = 57/205 (27%), Positives = 119/205 (58%), Gaps = 10/205 (4%)
Query: 15 ETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD-REREKQTDREGE 73
+ + R+++ RRE R++ +E + E +H + R++ +R +E RD +RE++T+R +
Sbjct: 411 QQLRREQQLRREQQLRREQ-EEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQ 469
Query: 74 RQRERERDRDRQRET-------ERERDKERETDRHTETDRERQKQKEREMERVRDREREK 126
+R+++ RD++ E E E +E++ R + RE+++++E+ ++R + ER +
Sbjct: 470 ERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQ 529
Query: 127 QKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERER 186
Q+ + E+Q RE + RE+ +RE E E++ ++ +RE+E +R++ KRE + R++
Sbjct: 530 QR-LRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQ 588
Query: 187 HTDMERERQRETDRKRDRQRESERE 211
E+E + E KR+ E+E
Sbjct: 589 RLKREQEERLEQRLKREEVERLEQE 613
Score = 99.8 bits (247), Expect = 2e-21
Identities = 73/231 (31%), Positives = 117/231 (50%), Gaps = 27/231 (11%)
Query: 2 ESKTEGRHTHTETETMDRQRERRR----------ETDRERDRAKESKTEDRHSERDRQRD 51
+S+ + +H E + DR++ERRR E ER+ KE+K DR S+ ++Q
Sbjct: 1262 QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLL 1321
Query: 52 RE------RNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETD 105
RE R +E DR E+Q +E E Q R ++RDR+ E R +E+ E
Sbjct: 1322 REEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQ 1381
Query: 106 RERQKQKER----EMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTE 161
R R++++ER E +++R +ERE+Q R+R+ RE E+Q R+ + R+ E
Sbjct: 1382 RLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKF-----REEEQQLSRQERDRKFREEE 1436
Query: 162 DRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERER 212
+ R +ERERK E ++ +ERH E Q +R+ + ER+R
Sbjct: 1437 QQVRRQERERKFLEEEQQ--LRQERHRKFREEEQLLQEREEQQLHRQERDR 1485
Score = 98.6 bits (244), Expect = 3e-21
Identities = 65/226 (28%), Positives = 112/226 (49%), Gaps = 14/226 (6%)
Query: 2 ESKTEGRHTHTETET-MDRQRERRR-------ETDR-ERDRAKESKTEDRHSER-DRQRD 51
E + E +H E + R++E RR ET+R E++R K+ D+ ER +R
Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK 490
Query: 52 RERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQ 111
E R++ RE+Q RE E +RE+ R + E ++R + + R + +R Q
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLL 550
Query: 112 KEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRER---- 167
K E +R+ RE++ + +E + D+ RE ER+ +R + ER + RE
Sbjct: 551 KREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERL 610
Query: 168 ERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
E+E +RE+ KRE E ER + + ++E R++ +RE + R+
Sbjct: 611 EQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE 656
Score = 97.8 bits (242), Expect = 6e-21
Identities = 61/208 (29%), Positives = 111/208 (53%), Gaps = 11/208 (5%)
Query: 13 ETETMDRQRERRRET---DRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTD 69
E ET ++ERR++ D+E +R + + R++Q RE+ R+++ RE++
Sbjct: 461 EEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLK 520
Query: 70 REGERQRERERDRD-----RQRETERERDKERETDRHTETDRERQKQKEREMERVRDR-- 122
R+ E +R ++R R R++E RE+ +RE ++ E +R Q+ K RE E RD+
Sbjct: 521 RQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLK-REQEERRDQLL 579
Query: 123 EREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETK 182
+RE+++ R ++ E +R ++ E ER ER+ + RE E +R++ K E +
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ 639
Query: 183 ERERHTDMERERQRETDRKRDRQRESER 210
E R + RE+Q +++ R+ E ER
Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEER 667
Score = 97.4 bits (241), Expect = 8e-21
Identities = 57/213 (26%), Positives = 106/213 (49%), Gaps = 8/213 (3%)
Query: 1 MESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDR 60
+E + + + R++E RRE +R +E + SE+ +R++E RE+
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLL 550
Query: 61 DREREKQTDREGERQR-ERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERV 119
RE EK+ ++E QR +RE++ R + +RE ++ ++ + + +R Q+ K E+ER+
Sbjct: 551 KREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERL 610
Query: 120 RDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179
ER RE++ RE E RQ + E ER+ + RE++ R++ +R+
Sbjct: 611 EQEER-------REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREE 663
Query: 180 ETKERERHTDMERERQRETDRKRDRQRESERER 212
E + E+ E E +R + ++E RER
Sbjct: 664 EEERLEQRLKREHEEERREQELAEEEQEQARER 696
Score = 94.4 bits (233), Expect = 7e-20
Identities = 65/206 (31%), Positives = 126/206 (61%), Gaps = 16/206 (7%)
Query: 19 RQRERRRETDRERDRAKESKTEDRH-----SERDRQRDRERNRERDRDREREKQTDREGE 73
R+ E+ R+ + + R ++S+ + +H ERDR+++R R ++RDR E+Q +RE +
Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304
Query: 74 RQRERERDRDRQRETERERDKERETDRHTETDR----ERQKQKEREMERVRDREREKQ-- 127
++ +R RDR Q E + R++ E R ETDR E Q +ERE + +R +ER+++
Sbjct: 1305 KEAKR-RDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFR 1363
Query: 128 KEMGRERQTDRE--TDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERE 185
+E R ++ R+ + +R R+ ERER+ +E + + R +ERE++ +++R+RK +E +
Sbjct: 1364 EEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQ-QLRCQEREQQLRQDRDRKFR-EEEQ 1421
Query: 186 RHTDMERERQRETDRKRDRQRESERE 211
+ + ER+R+ + ++ R++E ER+
Sbjct: 1422 QLSRQERDRKFREEEQQVRRQERERK 1447
Score = 94.0 bits (232), Expect = 9e-20
Identities = 54/198 (27%), Positives = 106/198 (53%), Gaps = 1/198 (0%)
Query: 17 MDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERN-RERDRDREREKQTDREGERQ 75
++ +R+RRR T + +E +++ ++ + + +R RE+ R +E+E+Q E + Q
Sbjct: 878 LEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQ 937
Query: 76 RERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQ 135
+E E+ +RE R +++ER+ + + ++ ++ E E+ R +EREK+ E Q
Sbjct: 938 QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ 997
Query: 136 TDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQ 195
+ E ER+ R +E R+ + +D ++ E + RE KR +ERER E E Q
Sbjct: 998 QEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQ 1057
Query: 196 RETDRKRDRQRESERERD 213
+E ++ +RE+ R ++
Sbjct: 1058 QEEEQLLGEERETRRRQE 1075
Score = 92.8 bits (229), Expect = 2e-19
Identities = 61/202 (30%), Positives = 114/202 (56%), Gaps = 14/202 (6%)
Query: 21 RERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERER 80
++RR+E D+ R ++ + E+ +R RQ+ +E+ RE E+ ++ +R +R R+R R
Sbjct: 111 QDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQR-R 169
Query: 81 DRD--RQRETERERDKERETD--------RHTETDRERQKQKEREMERVRDREREKQKEM 130
D + RQR+ +ER++ R + TE + ++ + RE+ +R + RE++++
Sbjct: 170 DEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQ 229
Query: 131 GRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDM 190
RERQ DR E E++ R+RET RK E++ +E E +R+RE + + E + ++
Sbjct: 230 RRERQ-DRVFQEEEEKE-WRKRETVL-RKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL 286
Query: 191 ERERQRETDRKRDRQRESERER 212
RERQ E +++ +RE + R
Sbjct: 287 RRERQEEEQQQQRLRREQQLRR 308
Score = 92.4 bits (228), Expect = 2e-19
Identities = 54/203 (26%), Positives = 107/203 (52%), Gaps = 5/203 (2%)
Query: 13 ETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREG 72
E + + + E+RR + ER +E + + + R+ +R +ER+R E++ R+
Sbjct: 1150 EEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209
Query: 73 ERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGR 132
+QR R+ D+ + + E +KE + + R+ ++ R++E + R+R+ Q+++
Sbjct: 1210 RKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQH 1269
Query: 133 ERQTDRETDRERERQ--AERERETGRERKTEDRHRERERERKRERERKRETKERERHTDM 190
+E DRE+ER+ +R+R E + E RE ++E KR + +E K+ R
Sbjct: 1270 LLGEQQERDREQERRRWQQRDRHFPEEEQLE---REEQKEAKRRDRKSQEEKQLLREERE 1326
Query: 191 ERERQRETDRKRDRQRESERERD 213
E+ R++ETDRK + + +ER+
Sbjct: 1327 EKRRRQETDRKFREEEQLLQERE 1349
Score = 90.9 bits (224), Expect = 7e-19
Identities = 70/239 (29%), Positives = 124/239 (51%), Gaps = 30/239 (12%)
Query: 4 KTEGRHTHTETETMDRQR--ERRRETDRERDRAKESKTEDRHSERD-------RQRDRER 54
+ E + E E + RQ+ +R R+ D+ D + + E ++ RD R+ ++ R
Sbjct: 1192 RQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR 1251
Query: 55 NRERDRDREREKQTD--------REGERQRERERDRDRQRETERERDKERETDRHTETDR 106
E + R+R+ Q D +E +R++ER R + R R E ERE + + R
Sbjct: 1252 QLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKR-R 1310
Query: 107 ERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRE-RKTEDRHR 165
+R+ Q+E+++ R E+ +++E R+ + + + +ERE Q R +E R+ R+ E RH+
Sbjct: 1311 DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQ 1370
Query: 166 ER------ERERKRERERKRE-TKERERHTDMERERQRETDRKR----DRQRESERERD 213
E+ E +R R +ER+R+ KE ++ ERE+Q DR R + Q+ S +ERD
Sbjct: 1371 EQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERD 1429
Score = 90.5 bits (223), Expect = 9e-19
Identities = 52/199 (26%), Positives = 107/199 (53%), Gaps = 5/199 (2%)
Query: 20 QRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRE---REKQTDREGERQR 76
+ ERR + +R + + + E R RQ + ER ++R R + RE++ RE +R
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR 552
Query: 77 ERERDRDRQRETER-ERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQ 135
E E+ +++R +R +R++E D+ + + ER++Q+ + + R +R K++E+ R Q
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612
Query: 136 TDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTD-MERER 194
+R R + + E ER + E R +++ R+ ++ER+ + +RE + +E+
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRL 672
Query: 195 QRETDRKRDRQRESERERD 213
+RE + +R Q +E E++
Sbjct: 673 KREHEEERREQELAEEEQE 691
Score = 90.5 bits (223), Expect = 9e-19
Identities = 68/257 (26%), Positives = 123/257 (47%), Gaps = 45/257 (17%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
E GR + + QRER+ + + R + E+ E+ R++ RER +E
Sbjct: 775 EKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFL 834
Query: 62 REREKQTDREGERQRERERD-----RDRQRETERERDK--------ERETDRHT------ 102
E E+ RE +Q + E D ++R+R E+ RD+ ER+ RHT
Sbjct: 835 EEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPA 894
Query: 103 --ETDRERQKQKEREMERVRDREREKQKEMGRERQTDRET------------DRERERQA 148
E R+ Q+ + E E ++ EREK++ +ERQ E +RE+ R+
Sbjct: 895 LQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQ 954
Query: 149 ERERETGRERKTE-----------DRHRERERERK-RERERKRETKERERHTDMERERQR 196
ERER+ +++K + ++ R +ERE+K RE E ++ +E+ + E+ R++
Sbjct: 955 ERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ 1014
Query: 197 ETDRKRDRQRESERERD 213
E +R+ ++ E ++E +
Sbjct: 1015 EWERQYRKKDELQQEEE 1031
Score = 90.5 bits (223), Expect = 9e-19
Identities = 63/220 (28%), Positives = 117/220 (53%), Gaps = 23/220 (10%)
Query: 13 ETETMDRQRERRRETDRERDRAKESKTEDRHS-------ERDRQRDRERN-RERDRDRER 64
E + + +RE+RR + ER +E + + E+ R+++ ER RE + ++
Sbjct: 1120 EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE 1179
Query: 65 EKQTDREGERQRERERDRD--RQRETERERDKERETDRHTETDRERQKQKEREMERVRD- 121
E+Q RE + +R +ER+R + E +R++ K+R D +D + Q + E+E VRD
Sbjct: 1180 EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKE-NAVRDN 1238
Query: 122 ------REREKQKEMG----RERQTDRETDRERERQAERERETGRERKTEDRHRERERER 171
RE E+ +++ R+RQ+ ++ Q ER+RE R R+ + R R E
Sbjct: 1239 KVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQER-RRWQQRDRHFPEEE 1297
Query: 172 KRERERKRETKERERHTDMERERQRETDRKRDRQRESERE 211
+ ERE ++E K R+R + E++ RE ++ R++E++R+
Sbjct: 1298 QLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRK 1337
Score = 90.1 bits (222), Expect = 1e-18
Identities = 61/193 (31%), Positives = 102/193 (52%), Gaps = 12/193 (6%)
Query: 26 ETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDR-EREKQTDREGERQRERERDRDR 84
E R R KES +DR E D++R R+R+ + + +R +Q +E ER+ ++
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156
Query: 85 QRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRER 144
++E +RD++R R E R+RQ+ +ERE R + + + K G E + + ++ R
Sbjct: 157 KQERLEQRDRQR---RDEELWRQRQEWQEREERRAEEEQLQSCK--GHETEEFPDEEQLR 211
Query: 145 ERQAERERETGRERKTEDRHRERERERKRERE---RKRET---KERERHTDMERERQRET 198
R+ R GRE K + R ++R + E E RKRET KE E+ + E +RQRE
Sbjct: 212 RRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQREL 271
Query: 199 DRKRDRQRESERE 211
+ ++ R+ ER+
Sbjct: 272 QEEEEQLRKLERQ 284
Score = 89.7 bits (221), Expect = 2e-18
Identities = 70/251 (27%), Positives = 125/251 (49%), Gaps = 39/251 (15%)
Query: 1 MESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERD- 59
+ES+ + R + + ++ +RRR+ E+ R +ES+ + + ER ++ +E + RD
Sbjct: 708 LESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDF 767
Query: 60 ---------RDREREKQTDREGER-QRERE-RDRDRQRETERERDKERETDRHTETDRER 108
+R R++ + R R QRER+ R +RQ+ +R +E E ++ RER
Sbjct: 768 TWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRER 827
Query: 109 QKQKE--REMERVRDREREKQ---KEMGRERQTDRETDRERER------QAERERETGRE 157
+K+ + E E+++ RER +Q +E G + +R +E+ R Q E ER+ R
Sbjct: 828 EKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRH 887
Query: 158 ------------RKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDR----K 201
RK + +E E E +RE KR +E+ER E + Q+E ++ +
Sbjct: 888 TLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREE 947
Query: 202 RDRQRESERER 212
R+++R ERER
Sbjct: 948 REKRRRQERER 958
Score = 89.7 bits (221), Expect = 2e-18
Identities = 56/225 (24%), Positives = 118/225 (52%), Gaps = 20/225 (8%)
Query: 8 RHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQ 67
R HT Q + R+E ++ +E + E+R R ++++R+ E +E E+
Sbjct: 884 RRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQL 943
Query: 68 TDREGERQRERERDRDRQRETERERDKER----ETDRHTETDRERQKQKEREMERVRDR- 122
E E++R +ER+R +++ + ++ +E+ E ++ +RE++ ++E E+++ ++
Sbjct: 944 LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQL 1003
Query: 123 ---EREKQKEMGRERQTDR--ETDRERERQAERERETGRERKTEDRHRERERERKRERER 177
EREK++ ERQ + E +E E+ ERE R ++ E ++RE E ++ E +
Sbjct: 1004 LREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQL 1063
Query: 178 KRETKERERHTDMERERQRETDRKR----------DRQRESERER 212
E +E R ++ER+ ++E + ++ +++R ERER
Sbjct: 1064 LGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERER 1108
Score = 89.7 bits (221), Expect = 2e-18
Identities = 61/211 (28%), Positives = 111/211 (52%), Gaps = 16/211 (7%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKT---EDRHSERDRQRDRERNRER 58
E + E E R +ER R+ E + +E + E+R + R ++ +R+ +E
Sbjct: 1025 ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEE 1084
Query: 59 DRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMER 118
+ +E E+ E E++R +ER+R + E E ++++E+ ER+K++ +E+ER
Sbjct: 1085 ELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQ------LLREEREKRRRQELER 1138
Query: 119 VRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERK 178
E E Q+E E Q RE +R RQ E ER+ R+ E+ +E E+ + E+E++
Sbjct: 1139 QYREEEEVQQE---EEQLLREEPEKRRRQ-ELERQ---YREEEELQQEEEQLLREEQEKR 1191
Query: 179 RETKERERHTDMERERQRETDRKRDRQRESE 209
R+ +ER+ + E +RQ+ R RD + S+
Sbjct: 1192 RQERERQYREEEELQRQKRKQRYRDEDQRSD 1222
Score = 89.4 bits (220), Expect = 2e-18
Identities = 68/236 (28%), Positives = 120/236 (50%), Gaps = 25/236 (10%)
Query: 2 ESKTEGRHTHTETETMDRQRER-RRETDRER--DRAKESKTEDRHSERDRQRDRERNRER 58
E + E R E +R+ +R +RE + ER R K E+R + + ++E+ RER
Sbjct: 637 EEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARER 696
Query: 59 DRDR--EREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETD-----RERQKQ 111
+ R + + Q + E + ++ + R R++E +R R ++ E R E++ ER +
Sbjct: 697 IKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHR 756
Query: 112 KEREMERVRDR----EREKQKEMGRERQTDRETDRE-RERQAERERETGRERK--TEDRH 164
+++E E+ RD + E++ E GR+R + R RE RERQ E RE++ E+
Sbjct: 757 QQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEE 816
Query: 165 RERERERKRERERKRETKERERHTDMERERQRETDRKRD-------RQRESERERD 213
+E+ R ++RERE++ + E E RER ++ + D R+R E+ RD
Sbjct: 817 KEQRRRQRREREKELQFLEEEEQL-QRRERAQQLQEEEDGLQEDQERRRSQEQRRD 871
Score = 89.4 bits (220), Expect = 2e-18
Identities = 55/214 (25%), Positives = 115/214 (53%), Gaps = 24/214 (11%)
Query: 13 ETETMDRQRERRRETDRERDRAKESKT---------EDRHSERDRQRDRERNRERDRDRE 63
E + + +RE+RR +RER +E + E+R + R ++ +R+ +E + +E
Sbjct: 1030 EEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQE 1089
Query: 64 REKQTDREGERQRERERDRDRQRETERERDKER----ETDRHTETDRERQKQKEREMERV 119
E+ E E++R +ER+R + E E ++++E+ E ++ + ERQ ++E E+++
Sbjct: 1090 EEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQE 1149
Query: 120 RDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179
++ ++ E R ++ +R+ E E Q E E+ E+ E R +ERER+ + E E +R
Sbjct: 1150 EEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQ--EKRRQERERQYREEEELQR 1207
Query: 180 ETKERERHTDMERERQRETDRKRDRQRESERERD 213
+ + ++R R+ D++ D + + E E++
Sbjct: 1208 QKR---------KQRYRDEDQRSDLKWQWEPEKE 1232
Score = 89.0 bits (219), Expect = 3e-18
Identities = 62/234 (26%), Positives = 119/234 (50%), Gaps = 22/234 (9%)
Query: 2 ESKTEGRHTHTETETMDRQRER----RRETDRERDRAKESKTEDRHSERDRQRDRERNRE 57
E + E R E E ++++ R +RE E R + K+E++ R +Q RE+
Sbjct: 595 EERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQER 654
Query: 58 RDRDREREKQTDREGER-QRERERDRDRQR--ETERERDKERETDRHTETDRERQKQKER 114
R++ +RE++ +R +R +RE E +R Q E E+E+ +ER R + + + + +
Sbjct: 655 REQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADA 714
Query: 115 EMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHR----ERERE 170
+V R R+++ + R+ Q ++ RE E Q + E R+++ E++ R + + E
Sbjct: 715 RQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAE 774
Query: 171 RKRERERKRET------KERERHTDMERERQRE-----TDRKRDRQRESERERD 213
K ER R+R + ++RER E +QRE + +++++R RER+
Sbjct: 775 EKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRERE 828
Score = 89.0 bits (219), Expect = 3e-18
Identities = 60/239 (25%), Positives = 120/239 (50%), Gaps = 42/239 (17%)
Query: 13 ETETMDRQRERRRETDRE------------RDRAKESKTEDRHSERDRQRDRERNRERDR 60
E E +++R +RRE ++E R+RA++ + E+ + D++R R + + RD+
Sbjct: 813 EEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872
Query: 61 --------DREREKQT---------DREGERQRERERDRDRQRETERERDKERETDRHTE 103
+R+R + T E+Q +E + + QRE ER+K R ++ +
Sbjct: 873 KWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQRE---EREKRRRQEQERQ 929
Query: 104 TDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDR 163
E Q Q+E E +RE+ +++E R+ + D++ ++ E+ E E R ++ E +
Sbjct: 930 YREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKK 989
Query: 164 HRERERERKRERERKRETKERERHTDMERERQRETD----------RKRDRQRESERER 212
+RE E ++ E + RE +E+ R + ER+ +++ + +R+++R ERER
Sbjct: 990 YREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERER 1048
Score = 89.0 bits (219), Expect = 3e-18
Identities = 60/223 (26%), Positives = 122/223 (54%), Gaps = 17/223 (7%)
Query: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRE 63
+ E E E R++E +++ +ERDR ED ++R+ + +ERDR
Sbjct: 1590 RQEQERKFMEDEQQLRRQEGQQQLRQERDRKFR---EDEQLLQEREEQQLHRQERDRKFL 1646
Query: 64 REKQTDREGERQRERERDRDRQ--------RETERERDKERETDRHTETDRERQKQKERE 115
E+ R ER+++ DRDR+ +E E ++ + +E DR + ++ +++ERE
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERE 1706
Query: 116 MERVRDREREKQKEMGR----ERQTDRETDRERERQAERERETGRERKTEDRHRERERER 171
+ +++ ++ +++E+ R E Q +ET++E+ R+ ER R+ E + RE ++ R
Sbjct: 1707 RKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRP-EREEQQLR 1765
Query: 172 KRERERK-RETKERERHTDMERERQRETDRKRDRQRESERERD 213
++ER+RK RE ++ + + ++ R +E+DRK + + +ER+
Sbjct: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQERE 1808
Score = 88.6 bits (218), Expect = 4e-18
Identities = 60/194 (30%), Positives = 108/194 (55%), Gaps = 9/194 (4%)
Query: 25 RETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDR 84
RE ++ R + ++S+ DR S++D Q +ERDR++ER + R+ E + +R+
Sbjct: 1245 RENEQFR-QLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREE 1303
Query: 85 QRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRER 144
Q+E +R ++R++ + RE +++K R E R E+Q RE Q R +R+R
Sbjct: 1304 QKEAKR---RDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDR 1360
Query: 145 ERQAE--RERETGRE-RKTEDRHRERERERK-RERERKRETKERERHTDMERERQ-RETD 199
+ + E R +E GR+ + E R R +ERERK + E++ +ERE+ +R+R+ RE +
Sbjct: 1361 KFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEE 1420
Query: 200 RKRDRQRESERERD 213
++ RQ + R+
Sbjct: 1421 QQLSRQERDRKFRE 1434
Score = 88.2 bits (217), Expect = 5e-18
Identities = 64/226 (28%), Positives = 108/226 (47%), Gaps = 33/226 (14%)
Query: 15 ETMDRQRERRRETDRERDRAKESKTEDRHSERDRQ--------RDRERNRERDRDREREK 66
+ ++RQ E +E ++ + E R ER+RQ R + + R RD D+ +
Sbjct: 1164 QELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDL 1223
Query: 67 QTDREGERQ----------RERERDRDRQRETERERDKERETD----------RHTETDR 106
+ E E++ + RE ++ RQ E + RD++ + D R E +R
Sbjct: 1224 KWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQER 1283
Query: 107 ERQKQKEREMERVRDREREKQKE---MGRERQTDRETDRERERQAERERETGRE-RKTED 162
R +Q++R ERE+QKE R+ Q +++ RE + R +ET R+ R+ E
Sbjct: 1284 RRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQ 1343
Query: 163 RHRERERERKRERERKRETKERE-RHTDMERERQRETDRKRDRQRE 207
+ERE + R +ER R+ +E E RH + R+ E R R ++RE
Sbjct: 1344 LLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERE 1389
Score = 87.0 bits (214), Expect = 1e-17
Identities = 66/227 (29%), Positives = 113/227 (49%), Gaps = 28/227 (12%)
Query: 15 ETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDR-----DREREKQTD 69
+ + RQ E R R R + + ++ E+ +R+ E+ E++R RE+E++ D
Sbjct: 517 QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576
Query: 70 REGERQRERERDRDRQRETER--ERDKERETDRHTETDRERQKQKEREMERVR------- 120
+ +R+ ER + R ++ + ER +R K E +R + +R Q+ K E E R
Sbjct: 577 QLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKS 636
Query: 121 -DREREKQKEMGRERQTDRETDRERERQAER-ERETGRERKTEDRHR---ERERERKRER 175
++E +Q+++ RE+Q RE +RE + ER E+ RE + E R + E E+E+ RER
Sbjct: 637 EEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARER 696
Query: 176 ERKRETK---ERERHTD------MERERQRETDRKRDRQRESERERD 213
+ R K + E D R R++E R+R Q E R R+
Sbjct: 697 IKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRE 743
Score = 87.0 bits (214), Expect = 1e-17
Identities = 61/221 (27%), Positives = 110/221 (49%), Gaps = 24/221 (10%)
Query: 15 ETMDRQRERRRETDRERDRAKESKTEDRHS----ERDRQRDRERNRERDRDREREKQTDR 70
+ + R+ E+R E +R R K + E R E +R++ R + + +R +R K+ +
Sbjct: 548 QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEV 607
Query: 71 EGERQRERERDRDRQRETERERDKERETDRHTETDRERQ---KQKEREMERVRDREREKQ 127
E Q ER R ++ E E ER ++ E R++Q +Q+ER +R++ E E++
Sbjct: 608 ERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEER 667
Query: 128 KEMGRERQTDRETDRERERQAERERETGRER------------KTEDRHRERE---RERK 172
E +R + E +R + AE E+E RER ++E R+ + R RK
Sbjct: 668 LEQRLKR--EHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRK 725
Query: 173 RERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
+E +R+R+ +E +R + +E +R +Q+E E+ RD
Sbjct: 726 QEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRD 766
Score = 87.0 bits (214), Expect = 1e-17
Identities = 59/208 (28%), Positives = 108/208 (51%), Gaps = 12/208 (5%)
Query: 13 ETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQR-DRERNRERDRDREREKQTDRE 71
E + + +RE RR + ER KE + + + R+ ++ R +ER+R E++ +E
Sbjct: 1060 EEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE 1119
Query: 72 GERQRERERDRDRQRETERERDKERETDRHTE--TDRERQKQKEREMERVRDREREKQKE 129
E+ ER++ R++E ER+ +E E + E E +K++ +E+ER E E Q+E
Sbjct: 1120 EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE 1179
Query: 130 ---MGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERE- 185
+ RE Q R +RER+ + E E + ++RK R ++ + K + E ++E R+
Sbjct: 1180 EEQLLREEQEKRRQERERQYREEEELQR-QKRKQRYRDEDQRSDLKWQWEPEKENAVRDN 1238
Query: 186 ----RHTDMERERQRETDRKRDRQRESE 209
+ + E+ RQ E + RDRQ + +
Sbjct: 1239 KVYCKGRENEQFRQLEDSQLRDRQSQQD 1266
Score = 87.0 bits (214), Expect = 1e-17
Identities = 61/234 (26%), Positives = 120/234 (51%), Gaps = 39/234 (16%)
Query: 13 ETETMDRQRERRRETDRERDRAKESKT---------EDRHSERDRQRDRERNRERDRDRE 63
E + + + E+RR +RER +E + E+R R ++ +R+ E + +E
Sbjct: 1090 EEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQE 1149
Query: 64 REKQTDREGERQRERERDRDRQRETERERDKE---RETDRHTETDRERQKQKEREMERVR 120
E+ E E++R +E +R + E E ++++E RE +RERQ ++E E++R +
Sbjct: 1150 EEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209
Query: 121 DREREKQKEMGRERQTDRETDRE------------RERQAERERETG--RERKT------ 160
++R + ++ + + E ++E RE + R+ E R+R++
Sbjct: 1210 RKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQH 1269
Query: 161 ---EDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERE 211
E + R+RE+ER+R ++R R E E+ +ERE Q+E ++RDR+ + E++
Sbjct: 1270 LLGEQQERDREQERRRWQQRDRHFPEEEQ---LEREEQKEA-KRRDRKSQEEKQ 1319
Score = 87.0 bits (214), Expect = 1e-17
Identities = 61/209 (29%), Positives = 113/209 (54%), Gaps = 13/209 (6%)
Query: 13 ETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREG 72
E E + ++RE ++ +ERDR E+ R ++R+++ +RDR E+Q +EG
Sbjct: 1623 EDEQLLQEREEQQLHRQERDR---KFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG 1679
Query: 73 ERQRERERDRDRQ--------RETERERDKERETDRHTETDRERQKQKEREMERVRDRER 124
E Q+ R ++RDR+ R ERER +E + + ER+ ++E ++ + ++E+
Sbjct: 1680 EEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQ 1739
Query: 125 EKQKEMGRERQTDRETDRERERQAERERETGRE-RKTEDRHRERERERKRERERKRETKE 183
+++E R+ + + ERE Q R +E R+ R+ E +ERE ++ R +E R+ +E
Sbjct: 1740 LRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE 1799
Query: 184 RERHTDMERERQRETDRKRDRQRESERER 212
E+ ERE Q+ ++RD + E E+
Sbjct: 1800 EEQ-LRQEREEQQLRPQQRDGKYRWEEEQ 1827
Score = 86.7 bits (213), Expect = 1e-17
Identities = 68/251 (27%), Positives = 123/251 (49%), Gaps = 41/251 (16%)
Query: 2 ESKTEGRHTHTETETMDRQRE---RRRETDR--------------------ERDRAKESK 38
E+K R + E + + +RE RR+ETDR ERDR K +
Sbjct: 1306 EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDR-KFRE 1364
Query: 39 TEDRHSERDRQRDRERNRERDRDRER----EKQTDREGERQRERERDRDRQRETERERDK 94
E RH E+ R+ E R R ++RER E+Q R ER+++ +DRDR+ E ++
Sbjct: 1365 EELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLS 1424
Query: 95 ERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERET 154
+E DR + ++ +++ERE + + + ++ +Q+ + R+ ++ E+Q R+
Sbjct: 1425 RQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERD 1484
Query: 155 GRERKTEDRHRERERERK-RERERKRETKER------------ERHTDMERERQRETDRK 201
+ + E + R +ER+RK RE+E + + ER +R +E Q+ ++
Sbjct: 1485 RKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQE 1544
Query: 202 RDRQRESERER 212
R +QR +R+R
Sbjct: 1545 RGQQRRQDRDR 1555
Score = 86.3 bits (212), Expect = 2e-17
Identities = 64/212 (30%), Positives = 108/212 (50%), Gaps = 20/212 (9%)
Query: 20 QRERR-----RETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGER 74
Q ERR RE +R + R K + E+R +R ++ + ER + +R +R K+ + E ER
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQ-EERLEQRLKREEVERLEQEERREQRLKREEPEEER 629
Query: 75 QRE----RERDRDRQRETERERDKERETDRHTETDRERQKQK---EREMERVRDREREKQ 127
+++ E++ RQ++ RE+ + RE E + ER +Q+ E E ER E++
Sbjct: 630 RQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE 689
Query: 128 KEMGRERQTDR----ETDRERERQAERERETGRERKTEDRHRERERE---RKRERERKRE 180
+E RER R + E E A + + R RK E + R +E+E R+RE E + +
Sbjct: 690 QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQ 749
Query: 181 TKERERHTDMERERQRETDRKRDRQRESERER 212
+ER E E++R+ + + +SER R
Sbjct: 750 EEERAHRQQQEEEQRRDFTWQWQAEEKSERGR 781
Score = 86.3 bits (212), Expect = 2e-17
Identities = 50/199 (25%), Positives = 115/199 (57%), Gaps = 4/199 (2%)
Query: 18 DRQRERRRETDRE-RDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQR 76
+ Q+ RR+E DR+ R+ ++ + ++R + ++ + R +E +R E+Q +E E+++
Sbjct: 1680 EEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQ 1739
Query: 77 ERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQT 136
R ++R R+ E + ERE + +R+R+ ++E ++ + R+ ++ + +E R+ +
Sbjct: 1740 LRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE 1799
Query: 137 DRETDRERERQAER-ERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQ 195
+ + +ERE Q R ++ G+ R E++ + E+E++ +ER R+ + E+ E+ R+
Sbjct: 1800 EEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRR 1859
Query: 196 RETD--RKRDRQRESERER 212
E + ++ +++R ERER
Sbjct: 1860 EEQELWQEEEQKRRQERER 1878
Score = 85.9 bits (211), Expect = 2e-17
Identities = 63/206 (30%), Positives = 115/206 (55%), Gaps = 16/206 (7%)
Query: 13 ETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQR---DRERNRERDRDR----ERE 65
E E R++ER R+ +E + + + E + E ++ R ++E+ R ++R R E +
Sbjct: 1695 EEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQ 1754
Query: 66 KQTDREGERQRERERDRDRQRETERERDKERETDRHTETDR----ERQKQKEREMERVRD 121
+ +RE ++ R +ERDR + E + +++E + R E+DR E Q ++ERE +++R
Sbjct: 1755 LRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRP 1814
Query: 122 REREKQKEMGRERQTDRETDRERERQAERERETGRERK--TEDRHRERERERKRERERKR 179
++R+ K E Q E +R RQ ER+R+ E + T+++ R E+E +E E+KR
Sbjct: 1815 QQRDG-KYRWEEEQLQLEEQEQRLRQ-ERDRQYRAEEQFATQEKSRREEQELWQEEEQKR 1872
Query: 180 ETKERERHTDMERERQRETDRKRDRQ 205
+ERER E R+++ + +R RQ
Sbjct: 1873 R-QERERKLREEHIRRQQKEEQRHRQ 1897
Score = 85.1 bits (209), Expect = 4e-17
Identities = 60/208 (28%), Positives = 109/208 (52%), Gaps = 13/208 (6%)
Query: 13 ETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREG 72
E E R++ER ++ +RDR E+ ++ + + R +ERDR E+Q R
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFR---EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQ 1703
Query: 73 ERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKER-----EMERVRDREREKQ 127
ER+R+ ++ + R E ER E ET++E+ +++ER E E++R E+Q
Sbjct: 1704 ERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQ 1763
Query: 128 ---KEMGRERQTDRETDRERERQAERERETGRE-RKTEDRHRERERERKRERERKRETKE 183
+E R+ + + + +ERE Q R +E+ R+ R+ E +ERE ++ R ++R + +
Sbjct: 1764 LRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRW 1823
Query: 184 RERHTDMERERQRETDRKRDRQRESERE 211
E +E + QR ++RDRQ +E +
Sbjct: 1824 EEEQLQLEEQEQR-LRQERDRQYRAEEQ 1850
Score = 84.7 bits (208), Expect = 5e-17
Identities = 68/228 (29%), Positives = 121/228 (53%), Gaps = 33/228 (14%)
Query: 18 DRQRERRRETDR---ERDRAKESKTEDRHS--ERDRQRDRERNRERDRDREREKQTD--- 69
+R ++RR++ DR E ++ ++ + E + S ERDR+ E + R +++ER+ D
Sbjct: 1544 ERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQ 1603
Query: 70 ---REGERQRERERDRDRQRETERERDKERETDRHTETDRE--------RQKQKEREMER 118
+EG++Q +ERDR + + + +++E + E DR+ R++++E+++
Sbjct: 1604 LRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRH 1663
Query: 119 VRD---REREKQKEMGRERQTDR-ETDRERERQAERERETGRERK---TEDRHRERERER 171
RD RE E+ + G E+Q R E DR+ + ++ R RERK E + R +E ER
Sbjct: 1664 DRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELER 1723
Query: 172 K-RERERKRETKERERHTDMER------ERQRETDRKRDRQRESERER 212
K RE E+ R+ E+E+ ER E Q +R+ + R ER+R
Sbjct: 1724 KFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDR 1771
Score = 83.2 bits (204), Expect = 2e-16
Identities = 53/210 (25%), Positives = 108/210 (51%), Gaps = 10/210 (4%)
Query: 8 RHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERD--RDRERE 65
R + + R++E R E +R+ + + E+R +R ++ + E R + + E+E
Sbjct: 581 REEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQE 640
Query: 66 KQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQ---KQKEREMERVRDR 122
++ ++ R+++ R++ +RE E ER ++R H E RE++ +++E+ ER++ R
Sbjct: 641 ERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSR 700
Query: 123 --EREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRE 180
+ + Q E + + + R R+++ +R R+ E++ R RE E + + E R+
Sbjct: 701 IPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKR---RRRESELQWQEEERAHRQ 757
Query: 181 TKERERHTDMERERQRETDRKRDRQRESER 210
+E E+ D + Q E +R RQR S R
Sbjct: 758 QQEEEQRRDFTWQWQAEEKSERGRQRLSAR 787
Score = 82.8 bits (203), Expect = 2e-16
Identities = 57/212 (26%), Positives = 113/212 (53%), Gaps = 13/212 (6%)
Query: 13 ETETMDRQRERRRETDRERDRAKE-------SKTEDRHSERDRQRDRERNRERDRDRERE 65
E + ++RE++ DR+R +E + + R ERDR+ E + R ++RER+
Sbjct: 1649 EPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERK 1708
Query: 66 KQTDREGERQRERERD--RDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRE 123
+ + R++E ER + Q E E+++ R +R+ + E Q + ERE +++R +E
Sbjct: 1709 FLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQE 1768
Query: 124 REKQKEMGRERQTDRETDRERERQAE---RERETGRERKTEDRHRERERERK-RERERKR 179
R+++ + + +RE + R ++++ RE E R+ + E + R ++R+ K R E +
Sbjct: 1769 RDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQL 1828
Query: 180 ETKERERHTDMERERQRETDRKRDRQRESERE 211
+ +E+E+ ER+RQ + + Q +S RE
Sbjct: 1829 QLEEQEQRLRQERDRQYRAEEQFATQEKSRRE 1860
Score = 82.0 bits (201), Expect = 3e-16
Identities = 65/217 (29%), Positives = 107/217 (49%), Gaps = 13/217 (5%)
Query: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQ---RDRERNRERDR 60
K E E E + ++E+ RE + R + + E R + R R++ +R R
Sbjct: 673 KREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRR 732
Query: 61 DREREKQTDREGERQ-RERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERV 119
+ EK+ RE E Q +E ER +Q+E E+ RD + +++R RQ+ R R
Sbjct: 733 QEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLR- 791
Query: 120 RDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179
RER+ + E ERQ + E + E+ R RER+ E + E E + +R RER +
Sbjct: 792 EQRERQLRAE---ERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQR-RERAQ 847
Query: 180 ETKERERHTDMERERQRETDRKRDR----QRESERER 212
+ +E E ++ER+R +++RD+ Q E ER+R
Sbjct: 848 QLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKR 884
Score = 82.0 bits (201), Expect = 3e-16
Identities = 70/252 (27%), Positives = 126/252 (50%), Gaps = 43/252 (17%)
Query: 4 KTEGRHTHTETETMDRQRERRRETDRERDRA-KESKTEDRHSERDRQRDRERNRERDRDR 62
+ E E E + ++RE ++ +ERDR E + + R ERDR+ + R ++ +R
Sbjct: 1456 RQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPER 1515
Query: 63 E------------------REKQTDREGERQRERERDRDRQRETERERDKERETDRHTET 104
+ +E+Q R ER ++R +DRDR+ E + +ERE + +
Sbjct: 1516 KFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQ 1575
Query: 105 DRER----QKQKEREMERVRD--------REREKQKEMGRER----QTDRETDRERERQA 148
+R+R ++QK R E+ R R +E Q+++ +ER + D + +ERE Q
Sbjct: 1576 ERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQ 1635
Query: 149 ERERETGR---ERKTEDRHRERERERKRERERK-RETKERERHTDMERERQRETDRK--- 201
+E R E + + R +ERE++ + +R+RK RE ++ + + ++ R++E DRK
Sbjct: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFRE 1695
Query: 202 -RDRQRESERER 212
+ R ERER
Sbjct: 1696 EEQQLRRQERER 1707
Score = 81.6 bits (200), Expect = 4e-16
Identities = 61/226 (26%), Positives = 113/226 (50%), Gaps = 15/226 (6%)
Query: 1 MESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQ-RDRERNR--- 56
+ S+ R E + + RQ+ +R+ E+ ++ + + R +RDR+ R+ E+ R
Sbjct: 1508 LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQER 1567
Query: 57 --------ERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRER 108
ERDR E+Q R E++R+ D + R E ++ +E DR D +
Sbjct: 1568 EEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQL 1627
Query: 109 QKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAE-RERETGRERKTEDRHRER 167
+++E + ++R+R+ +E + R+ +RE +R + RE E + E + R +
Sbjct: 1628 LQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQ 1687
Query: 168 ERERK-RERERKRETKERERHTDMERERQRETDRKRDRQRESERER 212
ER+RK RE E++ +ERER E ++ R + +R + RE E+ R
Sbjct: 1688 ERDRKFREEEQQLRRQERERKFLQEEQQLRRQELER-KFREEEQLR 1732
Score = 80.5 bits (197), Expect = 1e-15
Identities = 58/211 (27%), Positives = 112/211 (53%), Gaps = 18/211 (8%)
Query: 18 DRQRERRRETDR----ERDRA-KESKTEDRHSERDR---QRDRERNRERDRDREREKQTD 69
DR R+ R E + ERDR +E + + R ER+R + +++ +ER R E+Q
Sbjct: 1411 DRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLL 1470
Query: 70 REGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREM--ERVRDREREKQ 127
+E E Q+ ++RDR+ E ++ + +E DR R ++ ER+ E + +++Q
Sbjct: 1471 QEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQ 1530
Query: 128 KEMGRERQTDRETDRERERQAERER-----ETGRERKTEDRHRERERERKRERERKRETK 182
++ +E Q R +R ++R+ +R+R E R+ + E + +ER+RK E ++ +
Sbjct: 1531 RKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRR 1590
Query: 183 ERERHTDMERERQRETDRKRDRQRESERERD 213
+ + ME E+Q R+++ Q++ +ERD
Sbjct: 1591 QEQERKFMEDEQQL---RRQEGQQQLRQERD 1618
Score = 80.1 bits (196), Expect = 1e-15
Identities = 56/205 (27%), Positives = 112/205 (54%), Gaps = 16/205 (7%)
Query: 20 QRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERE 79
+ +R R +RER KE + + R ER++Q ++R+R + RE E+Q R+ ER R+
Sbjct: 1379 EEQRLRRQERERKFLKEEQ-QLRCQEREQQLRQDRDR---KFREEEQQLSRQ-ERDRKFR 1433
Query: 80 RDRDRQRETERER-----DKERETDRHTETDRERQKQKEREMERVRDREREK----QKEM 130
+ + R ERER +++ +RH + E Q +ERE +++ +ER++ +++
Sbjct: 1434 EEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQ 1493
Query: 131 GRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDM 190
R ++ DR+ + R E ER+ E + R + + + + E++ +R+ + ++R D
Sbjct: 1494 LRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDR 1553
Query: 191 ERERQRETD--RKRDRQRESERERD 213
+R+ + E ++R+ Q+ S +ERD
Sbjct: 1554 DRKFREEEQLRQEREEQQLSRQERD 1578
Score = 79.7 bits (195), Expect = 2e-15
Identities = 57/230 (24%), Positives = 120/230 (52%), Gaps = 19/230 (8%)
Query: 1 MESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQ-RDRERN---R 56
+ + +GR E + + RQ R+ E+ + + + +RDR+ R+ E+ +
Sbjct: 1367 LRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQ 1426
Query: 57 ERDRDREREKQTDREGERQR-------ERERDRDRQRETERERDKERETDRHTETDRERQ 109
ERDR E+Q R ER+R + ++R R+ E + +ERE + +R+R+
Sbjct: 1427 ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRK 1486
Query: 110 KQKEREMERVRDREREKQKEMGRERQTDR---ETDRERERQAERER----ETGRERKTED 162
+E + R ++R+R+ +++ R ++ +R E +++ RQ + + E R+
Sbjct: 1487 FLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERG 1546
Query: 163 RHRERERERK-RERERKRETKERERHTDMERERQRETDRKRDRQRESERE 211
+ R ++R+RK RE E+ R+ +E ++ + ER+R+ + ++ R++E ER+
Sbjct: 1547 QQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERK 1596
Score = 79.0 bits (193), Expect = 3e-15
Identities = 53/201 (26%), Positives = 112/201 (55%), Gaps = 10/201 (4%)
Query: 18 DRQRERRRETDRERDRAKESKTEDRHSE--RDRQRDRERNRERDRDREREKQTDREGERQ 75
+ Q+ RR+E +R+ ++ ++RH + + Q +ER ++ +ER+++ E ++
Sbjct: 1435 EEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQL 1494
Query: 76 RERERDRDRQRETERERDKERETDRHTETDRERQKQKE--REMERVRDREREKQKEMGRE 133
R +ERDR + + R ++ ER+ + +Q+Q++ +E +++R +ER +Q+ R+
Sbjct: 1495 RRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRD 1554
Query: 134 RQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERK-RETKERERHTDMER 192
R+ E E+ RQ E++ R+ + E ++ R++E+ERK E +++ R + ++
Sbjct: 1555 RKFREE---EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQ 1611
Query: 193 ERQRETDRK--RDRQRESERE 211
+ ++E DRK D Q ERE
Sbjct: 1612 QLRQERDRKFREDEQLLQERE 1632
Score = 77.8 bits (190), Expect = 6e-15
Identities = 53/189 (28%), Positives = 100/189 (52%), Gaps = 7/189 (3%)
Query: 13 ETETMDRQRER-RRETDRERDRAKESKT---EDRHSERDRQRDRERNRERDRDREREKQT 68
E E R+ E+ R+ET++E+ R +E E+ +R+ + R +ERDR E+Q
Sbjct: 1720 ELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQL 1779
Query: 69 DREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQK 128
+E E Q+ R ++ DR+ E + +ERE + R+ + + E E ++ ++E+ ++
Sbjct: 1780 RQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQ 1839
Query: 129 EMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHT 188
E R+RQ E + ++ RE + + + + R +ERER + RE +R+ KE +RH
Sbjct: 1840 E--RDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERER-KLREEHIRRQQKEEQRHR 1896
Query: 189 DMERERQRE 197
+ + +E
Sbjct: 1897 QVGEIKSQE 1905
Score = 75.9 bits (185), Expect = 2e-14
Identities = 50/227 (22%), Positives = 122/227 (53%), Gaps = 17/227 (7%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
E + + R E + ++ +++ R+E R + R +E ++R ++ +++R+R +
Sbjct: 1434 EEEQQVRRQERERKFLEEEQQLRQERHR-KFREEEQLLQEREEQQLHRQERDRKFLEEEQ 1492
Query: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121
+ R ++ DR+ Q R ++ +R+ E ++ ++ R + ++ +++ER +R +D
Sbjct: 1493 QLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQD 1552
Query: 122 RERE--KQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179
R+R+ +++++ +ER+ + + +ER+R+ E + R ++ E + E E++ +R+ +++
Sbjct: 1553 RDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612
Query: 180 ETKERER------HTDMERERQRETDRKRDRQ--------RESERER 212
+ER+R ERE Q+ ++RDR+ R ERE+
Sbjct: 1613 LRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQ 1659
Score = 75.5 bits (184), Expect = 3e-14
Identities = 48/176 (27%), Positives = 102/176 (57%), Gaps = 7/176 (3%)
Query: 12 TETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQ-RDRERNR-ERDRDREREKQTD 69
TE E + RQ R+ + E+ R + + + R ERDR+ R+ E+ R ER+ + R +++D
Sbjct: 1735 TEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESD 1794
Query: 70 REGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKE 129
R + RE E+ R ++RE ++ R ++R+ E ++ + +++E+ + + RDR+ +++
Sbjct: 1795 R---KFREEEQLR-QEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQ 1850
Query: 130 MGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERE 185
+ ++ RE ++E ++ E++R RERK + H R+++ ++ + E K +E
Sbjct: 1851 FATQEKSRRE-EQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQE 1905
Score = 63.9 bits (154), Expect = 1e-10
Identities = 44/155 (28%), Positives = 76/155 (49%), Gaps = 9/155 (5%)
Query: 61 DREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVR 120
D E+ + D + ++R ++ D++R R+R E E + R RQK++E+E E
Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQ-----RRRQKRQEQERELAE 150
Query: 121 DREREKQKEMGRER---QTDRETDRERERQAERERETGRERKTED-RHRERERERKRERE 176
E+ +++E +R + D E R+R+ ERE E + + + E E E+
Sbjct: 151 GEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQL 210
Query: 177 RKRETKERERHTDMERERQRETDRKRDRQRESERE 211
R+RE E R E+++QR + R Q E E+E
Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKE 245
Score = 47.0 bits (110), Expect = 1e-05
Identities = 31/113 (27%), Positives = 61/113 (53%), Gaps = 6/113 (5%)
Query: 102 TETDRERQKQKEREMERVRDREREKQKEM--GRERQTDRET-DRERERQAERERETGRER 158
T D E++ + + + ++DR +E+ + R+RQ + E R R+++ E+ERE
Sbjct: 93 TGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELA--- 149
Query: 159 KTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERE 211
+ E++ ++ER +R+R+R+ E R+R ERE +R + + + E E
Sbjct: 150 EGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETE 202
Score = 28.5 bits (62), Expect = 4.4
Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 16/67 (23%)
Query: 147 QAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQR 206
+ +R R G+E +DR +E ++ R R+R+ E E +R RQ+
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLE----------------EEPGQRRRQK 140
Query: 207 ESERERD 213
E+ER+
Sbjct: 141 RQEQERE 147
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 110 bits (276), Expect = 7e-25
Identities = 55/190 (28%), Positives = 109/190 (57%), Gaps = 9/190 (4%)
Query: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQR---------DRER 54
K R + ++R R+RR E +R + +++ ++ D + + R
Sbjct: 446 KQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIR 505
Query: 55 NRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKER 114
RER+++REREK+ ++E E++RE+ER++DR+R+ E+E++ E+E ++ E ++ER+++KE+
Sbjct: 506 EREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEK 565
Query: 115 EMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRE 174
E+ER +++E+E QK +E++ + E +RE+ + RE E E + E ++ E
Sbjct: 566 ELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEE 625
Query: 175 RERKRETKER 184
R+ R
Sbjct: 626 PVFTRQDSNR 635
Score = 106 bits (264), Expect = 2e-23
Identities = 62/205 (30%), Positives = 120/205 (58%), Gaps = 12/205 (5%)
Query: 13 ETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRER---EKQTD 69
E E ++R ++ E +RA++ + E+ ++++ + + D + EKQ
Sbjct: 441 EDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPS 500
Query: 70 REGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKE 129
E R+RERE++R+R++E E+E+++ERE +R E DRERQ++KE+E+E +E+EKQ+E
Sbjct: 501 PEEIREREREKEREREKELEKEQEQEREKER--EKDRERQQEKEKELE----KEQEKQRE 554
Query: 130 MGRERQTDRETDRERERQAERERETGRERKTE---DRHRERERERKRERERKRETKERER 186
M +ER+ ++E + ER+++ E+E + +E++ E ++ RE+ E+ RE E ++
Sbjct: 555 MEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQ 614
Query: 187 HTDMERERQRETDRKRDRQRESERE 211
++ ++ E R SE+E
Sbjct: 615 ESENSCNKEEEPVFTRQDSNRSEKE 639
Score = 91.3 bits (225), Expect = 6e-19
Identities = 52/159 (32%), Positives = 100/159 (62%), Gaps = 8/159 (5%)
Query: 59 DRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQK----QKER 114
D D +++ ++ E ER R R+ E ER +++R+ + R +K +K+
Sbjct: 440 DEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQP 499
Query: 115 EMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRE 174
E +R+REREK++E RE++ ++E ++ERE++ E++RE +E K ++ +E+E++R+ E
Sbjct: 500 SPEEIREREREKERE--REKELEKEQEQEREKEREKDRERQQE-KEKELEKEQEKQREME 556
Query: 175 RERKRE-TKERERHTDMERERQRETDRKRDRQRESERER 212
+ERK+E KE ER + E+E Q+ +++++ + E ERE+
Sbjct: 557 KERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREK 595
Score = 87.0 bits (214), Expect = 1e-17
Identities = 50/142 (35%), Positives = 89/142 (62%), Gaps = 8/142 (5%)
Query: 78 RERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRE-REKQKEMGR---- 132
+++ D ++ R ++ E E R+R++++ER ME R EK K +
Sbjct: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGI 494
Query: 133 -ERQTDRETDRERERQAERERETGRERKTE-DRHRERERERKRERERKRE-TKERERHTD 189
E+Q E RERER+ ERERE E++ E +R +ERE++R+R++E+++E KE+E+ +
Sbjct: 495 LEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQRE 554
Query: 190 MERERQRETDRKRDRQRESERE 211
ME+ER++E +++ +RQ+E E+E
Sbjct: 555 MEKERKQEKEKELERQKEKEKE 576
Score = 87.0 bits (214), Expect = 1e-17
Identities = 53/196 (27%), Positives = 112/196 (57%), Gaps = 11/196 (5%)
Query: 19 RQRERRRETDRERDRAKESKTE-DRHSERDRQRDRERNRERDRDREREKQTDREGERQRE 77
R+RER +E +RE++ KE + E ++ E+DR+R +E +E++ ++E+EKQ + E ER++E
Sbjct: 505 REREREKEREREKELEKEQEQEREKEREKDRERQQE--KEKELEKEQEKQREMEKERKQE 562
Query: 78 RERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTD 137
+E++ +RQ+E E+E K +E ++ E ++ER+K + E++ RE + M +++++
Sbjct: 563 KEKELERQKEKEKELQKMKEQEKECELEKEREKLE----EKIEPRE-PNLEPMVEKQESE 617
Query: 138 RETDRERERQAERERETGRERKTEDRHRERERE---RKRERERKRETKERERHTDMERER 194
++E E R+ E++ E E E + R K+ ++ +R
Sbjct: 618 NSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQR 677
Query: 195 QRETDRKRDRQRESER 210
Q+E +++ Q++ ++
Sbjct: 678 QQEQMKQQQWQQQQQQ 693
Score = 65.1 bits (157), Expect = 4e-11
Identities = 39/184 (21%), Positives = 96/184 (52%), Gaps = 5/184 (2%)
Query: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTE-DRHSERDRQRDRERNRERDRDR 62
K R E E +++RE+ RE DRER + KE + E ++ +R+ +++R++ +E++ +R
Sbjct: 511 KEREREKELEKE-QEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELER 569
Query: 63 EREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQK---QKEREMERV 119
++EK+ + + +++E+E + +++RE E+ + RE + +++ + KE E
Sbjct: 570 QKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFT 629
Query: 120 RDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179
R +KE + R A + +K+ +R++E+ ++++ ++
Sbjct: 630 RQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQ 689
Query: 180 ETKE 183
+ ++
Sbjct: 690 QQQQ 693
Score = 51.2 bits (121), Expect = 6e-07
Identities = 32/108 (29%), Positives = 59/108 (54%), Gaps = 10/108 (9%)
Query: 110 KQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHR---- 165
KQ+ + + + + R +Q E+ + R+ E ER+ E +R+ K +
Sbjct: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGI 494
Query: 166 -ERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERER 212
E++ + RER+RE KERER ++E+E+++E R+++RE +RER
Sbjct: 495 LEKQPSPEEIRERERE-KEREREKELEKEQEQE----REKEREKDRER 537
Score = 33.5 bits (75), Expect = 0.14
Identities = 43/181 (23%), Positives = 67/181 (37%), Gaps = 31/181 (17%)
Query: 55 NRERDRDREREKQTDREGERQRER----ERDRDRQRETERERDKERETDRHTETDRERQK 110
N+ R E K D E R+ E+ D+ R + ER+ D RE R R ++
Sbjct: 1373 NQWNPRQSEVPKPEDGEPPRRHEQFIPIAADK-RPPKFERKFDPARERPRRQRPTRPPRQ 1431
Query: 111 QKEREMERVRDRE---------------------REKQKEMG--RERQTDRETDRERERQ 147
K R+R+RE +E +G +T +++ Q
Sbjct: 1432 DKPPRFRRLREREAASKSNEVVAVPTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQ 1491
Query: 148 AERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERE---RQRETDRKRDR 204
A E ET E + RER+ ++ + + K E +RE R + R DR
Sbjct: 1492 ANEEWETASESSDFNERRERDEKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRPVDR 1551
Query: 205 Q 205
Q
Sbjct: 1552 Q 1552
Score = 32.3 bits (72), Expect = 0.31
Identities = 27/136 (19%), Positives = 61/136 (44%), Gaps = 12/136 (8%)
Query: 63 EREKQTDREGERQRERERDRDRQRETERERDKE-----RETDRHTETDR--ERQKQKERE 115
ER + + R+R + ++ + +R + + T R ++ ER ++K ++
Sbjct: 910 ERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKK 969
Query: 116 MERVRDREREKQKEMGRERQTDR-----ETDRERERQAERERETGRERKTEDRHRERERE 170
+R E K +++ + + R ++R E R +G +K R + ERE
Sbjct: 970 EGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEERE 1029
Query: 171 RKRERERKRETKERER 186
+++E+E ++ K E+
Sbjct: 1030 QRKEKEGEKAEKVTEK 1045
Score = 31.6 bits (70), Expect = 0.52
Identities = 31/132 (23%), Positives = 58/132 (43%), Gaps = 10/132 (7%)
Query: 9 HTHTETETMDRQR-ERRRETDRERDRAKESKTE-DRHSERDRQRDRERNRERDRDRE--R 64
H T+ D QR E + R +SK +R E+ ++ R+ E + + +
Sbjct: 927 HGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYK 986
Query: 65 EKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKERE-MERVRDR- 122
K R G R R+ R R ++ R + +RE++K+KE E E+V ++
Sbjct: 987 SKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKV 1046
Query: 123 ----EREKQKEM 130
E+ ++K++
Sbjct: 1047 VVKPEKTEKKDL 1058
Score = 30.8 bits (68), Expect = 0.89
Identities = 47/206 (22%), Positives = 82/206 (39%), Gaps = 26/206 (12%)
Query: 29 RERDRAKESKTEDRHSERDRQRDRERNRERDRDRE-REKQTDRE----GERQRERERDRD 83
R+R+ + E+++E E +R R+R E D D E E +D++ G+ + ER +
Sbjct: 1237 RQREES-ETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERPEN 1295
Query: 84 RQRETERERDKERETDRHTETD-RERQKQKEREMERVR-----DREREKQKEMGRERQTD 137
++ K D H D R +K R+ ++ + E ++ G R+
Sbjct: 1296 KKPVKPHSSFK---PDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGG 1352
Query: 138 RETDRERERQAERERETGRERKTEDRHRERERERKRERERKRE----------TKERERH 187
R+ R + R R+ + R E + E R+ E + ER
Sbjct: 1353 RDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRRHEQFIPIAADKRPPKFERK 1412
Query: 188 TDMERER-QRETDRKRDRQRESERER 212
D RER +R+ + RQ + R R
Sbjct: 1413 FDPARERPRRQRPTRPPRQDKPPRFR 1438
Score = 27.3 bits (59), Expect = 9.9
Identities = 35/143 (24%), Positives = 52/143 (36%), Gaps = 9/143 (6%)
Query: 73 ERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMG- 131
+ +++ E+ + ER R R + T R KE RER+ + G
Sbjct: 1133 KEEKQPEKVISKDLVIERPRPDSRPAVKKESTLPPRTYWKEA-------RERDWFPDQGY 1185
Query: 132 RERQTDRETDRERE-RQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDM 190
R R R R R + R G T D + R+ + + E ++RE
Sbjct: 1186 RGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQREESETR 1245
Query: 191 ERERQRETDRKRDRQRESERERD 213
E KR RQR SE + D
Sbjct: 1246 SESSDFEVVPKRRRQRGSETDTD 1268
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 107 bits (268), Expect = 6e-24
Identities = 65/201 (32%), Positives = 108/201 (53%), Gaps = 12/201 (5%)
Query: 12 TETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDRE 71
T E ++ R+R E DR+ +R K+ K E E++R+R+RE RER R RE E +RE
Sbjct: 226 TVEELKEKLRKRTEEPDRD-ERLKKEKQEREEREKEREREREE-RERKRRREEE---ERE 280
Query: 72 GERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMG 131
ER R+RER R+R R R R +DR R+ ++ + RE R R R+R + +
Sbjct: 281 KERARDRER---RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHD 337
Query: 132 RERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDM- 190
R + R R+R R R+R++ + R + R+RE++RK + + KR + +++
Sbjct: 338 RSERKHRSRSRDRRRSKSRDRKSYKHR---SKSRDREQDRKSKEKEKRGSDDKKSSVKSG 394
Query: 191 ERERQRETDRKRDRQRESERE 211
RE+Q E ++ +++ E
Sbjct: 395 SREKQSEDTNTESKESDTKNE 415
Score = 101 bits (251), Expect = 5e-22
Identities = 61/181 (33%), Positives = 100/181 (55%), Gaps = 5/181 (2%)
Query: 34 AKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERE-RDRDRQRETERER 92
AK T + E+ R+R E +R+ +E++++ +RE ER+RERE R+R R+RE E ER
Sbjct: 221 AKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRRE-EEER 279
Query: 93 DKERETDR-HTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERE 151
+KER DR + R R + R +R R R+ ++ RER+ R DR R R +R
Sbjct: 280 EKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRS 339
Query: 152 RETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERE 211
R R + DR R + R+RK + R + +++RE+ + + +R +D K+ + RE
Sbjct: 340 ERKHRSR-SRDRRRSKSRDRKSYKHRSK-SRDREQDRKSKEKEKRGSDDKKSSVKSGSRE 397
Query: 212 R 212
+
Sbjct: 398 K 398
Score = 97.8 bits (242), Expect = 6e-21
Identities = 57/192 (29%), Positives = 99/192 (51%), Gaps = 7/192 (3%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
E + R + E +R++ER RE + ER+R + + E+R ER R R+R R R R R
Sbjct: 240 EPDRDERLKKEKQEREEREKERERERE-ERERKRRREEEEREKERARDRER-RKRSRSRS 297
Query: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121
R + +DR R R+ +R R R+R R RD+ R + R + ++R + RD
Sbjct: 298 RHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRD 357
Query: 122 REREKQKEMGRERQTDRETDRERERQAERERET----GRERKTEDRHRE-RERERKRERE 176
R+ K + R+R+ DR++ + +R ++ ++ + RE+++ED + E +E + K E
Sbjct: 358 RKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVN 417
Query: 177 RKRETKERERHT 188
E + E T
Sbjct: 418 GTSEDIKSEGDT 429
Score = 97.4 bits (241), Expect = 8e-21
Identities = 51/187 (27%), Positives = 95/187 (50%), Gaps = 5/187 (2%)
Query: 15 ETMDRQRERRRETDRERDRAKESKTEDRH---SERDRQRDRERNRERDRDREREKQTDRE 71
E + ++++ R E ++ER+R +E + R ER+++R R+R R R R R R + + R
Sbjct: 245 ERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRER-RKRSRSRSRHSSRT 303
Query: 72 GERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMG 131
+R+ R RD R R ER R + R+ R DR +K + R +R R + R+++
Sbjct: 304 SDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKH 363
Query: 132 RERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDME 191
R + DRE DR + ++ E+ ++ + RE++ E ++ +TK T +
Sbjct: 364 RSKSRDREQDR-KSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSED 422
Query: 192 RERQRET 198
+ + +T
Sbjct: 423 IKSEGDT 429
Score = 70.5 bits (171), Expect = 1e-12
Identities = 34/105 (32%), Positives = 62/105 (59%), Gaps = 3/105 (2%)
Query: 109 QKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERE 168
++ KE+ +R + +R+++ + ++ + +RE +RERER+ ERE R R+ E+R +ER
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKERERERE---ERERKRRREEEEREKERA 284
Query: 169 RERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
R+R+R + + ++ R +D R R+ R R R+R R RD
Sbjct: 285 RDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRD 329
Score = 53.9 bits (128), Expect = 1e-07
Identities = 49/145 (33%), Positives = 72/145 (49%), Gaps = 31/145 (21%)
Query: 94 KERETDRHTETDRERQKQKEREME----------------RVRDREREKQKEMGRER--- 134
+ERE R T + E +E++ME RV D KQ MG +
Sbjct: 167 EERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQ-HMGYAKIKA 225
Query: 135 --QTDRETDRERERQAERERETGRERKT-EDRHRERERERKRERERKRETKERERHTDME 191
+ +E R+R + +R+ +E++ E+R +ERERER+ ERERKR +E ER E
Sbjct: 226 TVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKRRREEEER----E 280
Query: 192 RERQRETDRK---RDRQRESERERD 213
+ER R+ +R+ R R R S R D
Sbjct: 281 KERARDRERRKRSRSRSRHSSRTSD 305
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 107 bits (268), Expect = 6e-24
Identities = 65/201 (32%), Positives = 108/201 (53%), Gaps = 12/201 (5%)
Query: 12 TETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDRE 71
T E ++ R+R E DR+ +R K+ K E E++R+R+RE RER R RE E +RE
Sbjct: 226 TVEELKEKLRKRTEEPDRD-ERLKKEKQEREEREKEREREREE-RERKRRREEE---ERE 280
Query: 72 GERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMG 131
ER R+RER R+R R R R +DR R+ ++ + RE R R R+R + +
Sbjct: 281 KERARDRER---RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHD 337
Query: 132 RERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDM- 190
R + R R+R R R+R++ + R + R+RE++RK + + KR + +++
Sbjct: 338 RSERKHRSRSRDRRRSKSRDRKSYKHR---SKSRDREQDRKSKEKEKRGSDDKKSSVKSG 394
Query: 191 ERERQRETDRKRDRQRESERE 211
RE+Q E ++ +++ E
Sbjct: 395 SREKQSEDTNTESKESDTKNE 415
Score = 101 bits (251), Expect = 5e-22
Identities = 61/181 (33%), Positives = 100/181 (55%), Gaps = 5/181 (2%)
Query: 34 AKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERE-RDRDRQRETERER 92
AK T + E+ R+R E +R+ +E++++ +RE ER+RERE R+R R+RE E ER
Sbjct: 221 AKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRRE-EEER 279
Query: 93 DKERETDR-HTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERE 151
+KER DR + R R + R +R R R+ ++ RER+ R DR R R +R
Sbjct: 280 EKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRS 339
Query: 152 RETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERE 211
R R + DR R + R+RK + R + +++RE+ + + +R +D K+ + RE
Sbjct: 340 ERKHRSR-SRDRRRSKSRDRKSYKHRSK-SRDREQDRKSKEKEKRGSDDKKSSVKSGSRE 397
Query: 212 R 212
+
Sbjct: 398 K 398
Score = 97.8 bits (242), Expect = 6e-21
Identities = 57/192 (29%), Positives = 99/192 (51%), Gaps = 7/192 (3%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
E + R + E +R++ER RE + ER+R + + E+R ER R R+R R R R R
Sbjct: 240 EPDRDERLKKEKQEREEREKERERERE-ERERKRRREEEEREKERARDRER-RKRSRSRS 297
Query: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121
R + +DR R R+ +R R R+R R RD+ R + R + ++R + RD
Sbjct: 298 RHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRD 357
Query: 122 REREKQKEMGRERQTDRETDRERERQAERERET----GRERKTEDRHRE-RERERKRERE 176
R+ K + R+R+ DR++ + +R ++ ++ + RE+++ED + E +E + K E
Sbjct: 358 RKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVN 417
Query: 177 RKRETKERERHT 188
E + E T
Sbjct: 418 GTSEDIKSEGDT 429
Score = 97.4 bits (241), Expect = 8e-21
Identities = 51/187 (27%), Positives = 95/187 (50%), Gaps = 5/187 (2%)
Query: 15 ETMDRQRERRRETDRERDRAKESKTEDRH---SERDRQRDRERNRERDRDREREKQTDRE 71
E + ++++ R E ++ER+R +E + R ER+++R R+R R R R R R + + R
Sbjct: 245 ERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRER-RKRSRSRSRHSSRT 303
Query: 72 GERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMG 131
+R+ R RD R R ER R + R+ R DR +K + R +R R + R+++
Sbjct: 304 SDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKH 363
Query: 132 RERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDME 191
R + DRE DR + ++ E+ ++ + RE++ E ++ +TK T +
Sbjct: 364 RSKSRDREQDR-KSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSED 422
Query: 192 RERQRET 198
+ + +T
Sbjct: 423 IKSEGDT 429
Score = 70.5 bits (171), Expect = 1e-12
Identities = 34/105 (32%), Positives = 62/105 (59%), Gaps = 3/105 (2%)
Query: 109 QKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERE 168
++ KE+ +R + +R+++ + ++ + +RE +RERER+ ERE R R+ E+R +ER
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKERERERE---ERERKRRREEEEREKERA 284
Query: 169 RERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
R+R+R + + ++ R +D R R+ R R R+R R RD
Sbjct: 285 RDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRD 329
Score = 53.9 bits (128), Expect = 1e-07
Identities = 49/145 (33%), Positives = 72/145 (49%), Gaps = 31/145 (21%)
Query: 94 KERETDRHTETDRERQKQKEREME----------------RVRDREREKQKEMGRER--- 134
+ERE R T + E +E++ME RV D KQ MG +
Sbjct: 167 EERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQ-HMGYAKIKA 225
Query: 135 --QTDRETDRERERQAERERETGRERKT-EDRHRERERERKRERERKRETKERERHTDME 191
+ +E R+R + +R+ +E++ E+R +ERERER+ ERERKR +E ER E
Sbjct: 226 TVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKRRREEEER----E 280
Query: 192 RERQRETDRK---RDRQRESERERD 213
+ER R+ +R+ R R R S R D
Sbjct: 281 KERARDRERRKRSRSRSRHSSRTSD 305
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 107 bits (268), Expect = 6e-24
Identities = 66/200 (33%), Positives = 102/200 (51%), Gaps = 16/200 (8%)
Query: 26 ETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRD-R 84
+T +RD+ KE + S R +R R R RER++++D EG + R R R ++ R
Sbjct: 15 KTSPDRDKKKE---QSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR 71
Query: 85 QRETERERDKERETDRHTETDRERQKQKER--EMERVRDREREKQKEMGRERQTDRETDR 142
+ E++ + K+ +++ H + + K +ER E DR + K+++ R R R R
Sbjct: 72 RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 131
Query: 143 ERE-RQAERERETGRER-----KTEDRHRERERERKRERERKR----ETKERERHTDMER 192
ER R RER+ R R K+ R RER++ R R RERKR ++ R RH R
Sbjct: 132 ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTR 191
Query: 193 ERQRETDRKRDRQRESERER 212
R R R RDR++ E+ R
Sbjct: 192 SRSRTRSRSRDRKKRIEKPR 211
Score = 97.1 bits (240), Expect = 1e-20
Identities = 62/190 (32%), Positives = 85/190 (44%), Gaps = 23/190 (12%)
Query: 27 TDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQR 86
+D ERD KT DR + +E++ R + R R RER+R D +
Sbjct: 4 SDTERDGLAPEKTSP-----DRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEG 58
Query: 87 ETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRER-- 144
R R + +E RH D+ +K K E ++E + GRER E +R
Sbjct: 59 RKHRSRSRSKEGRRHESKDKSSKKHKSEE-----HNDKEHSSDKGRERLNSSENGEDRHK 113
Query: 145 --ERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKR 202
ER++ R R R R E RHR R RERK+ R R RE K + R R +RK+
Sbjct: 114 RKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERK---------KSRSRSRERKK 164
Query: 203 DRQRESERER 212
R R ER+R
Sbjct: 165 SRSRSRERKR 174
Score = 96.7 bits (239), Expect = 1e-20
Identities = 57/184 (30%), Positives = 93/184 (50%), Gaps = 11/184 (5%)
Query: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRAK-ESKTEDRHSERDRQRDRERNRERDRD 61
S +H ++ + + R+R+R+ + + + R++ SK RH +D+ + ++ E +
Sbjct: 32 SPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHN-- 89
Query: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETD-RERQKQKEREMERVR 120
++E +D+ ER E DR + ER+ + R R + R R + +ER+ R R
Sbjct: 90 -DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSR 148
Query: 121 DREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRE 180
RER+K + RER+ R RER+R R R R R RHR R R R R R R R+
Sbjct: 149 SRERKKSRSRSRERKKSRSRSRERKR---RIRSRSRSR---SRHRHRTRSRSRTRSRSRD 202
Query: 181 TKER 184
K+R
Sbjct: 203 RKKR 206
Score = 96.3 bits (238), Expect = 2e-20
Identities = 69/227 (30%), Positives = 107/227 (47%), Gaps = 36/227 (15%)
Query: 11 HTETETMDRQRERRRETDRE------RDRAKESKTEDRHSERDRQRDRERNRERDRDRER 64
H + + R RER+R++D E R R+KE + RH +D+ + ++ E + ++
Sbjct: 38 HHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR---RHESKDKSSKKHKSEEHN---DK 91
Query: 65 EKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRE-RQKQKEREMERVRDRE 123
E +D+ ER E DR + ER+ + R R +R R + +ER+ R R RE
Sbjct: 92 EHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRE 151
Query: 124 REKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKE 183
R+K + RER+ R RER+R+ R R R R R R R R R R R+RK+ ++
Sbjct: 152 RKKSRSRSRERKKSRSRSRERKRRI-RSRSRSRSRHRH-RTRSRSRTRSRSRDRKKRIEK 209
Query: 184 -----------------RERHTDMERE----RQRETDRKRDRQRESE 209
R R+T M+ + R+ E +K QRE E
Sbjct: 210 PRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKE 256
Score = 94.0 bits (232), Expect = 9e-20
Identities = 52/195 (26%), Positives = 92/195 (47%), Gaps = 4/195 (2%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
+ K E R R RER R +++ +H R R ++ R+ +D+
Sbjct: 21 DKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGR-KHRSRSRSKEGRRHESKDKS 79
Query: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKERE-MERVR 120
++ K ++ +++ ++ R+R +E D+ + +R + R + + RE R R
Sbjct: 80 SKKHK-SEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSR 138
Query: 121 DREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRE 180
RER+K + RER+ R RER++ R RE R ++ R R R R R R R R R
Sbjct: 139 SRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTR- 197
Query: 181 TKERERHTDMERERQ 195
++ R+R +E+ R+
Sbjct: 198 SRSRDRKKRIEKPRR 212
Score = 81.3 bits (199), Expect = 6e-16
Identities = 51/168 (30%), Positives = 75/168 (44%), Gaps = 10/168 (5%)
Query: 1 MESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDR 60
+ S G H E R+ R R R R R + ++ R ++ R R RER + R R
Sbjct: 102 LNSSENGEDRHKRKE---RKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSR 158
Query: 61 DREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVR 120
RER+K R ER+R R R R R R R R + R R DR+++ +K R R
Sbjct: 159 SRERKKSRSRSRERKR-RIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSL 217
Query: 121 DREREKQKEMGRERQTD------RETDRERERQAERERETGRERKTED 162
R GR D R +R ++ Q +RE+E ++K ++
Sbjct: 218 SRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 107 bits (266), Expect = 1e-23
Identities = 75/216 (34%), Positives = 115/216 (53%), Gaps = 47/216 (21%)
Query: 8 RHTHTETETMDRQ-RERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREK 66
+H E +R RE+ E +RE +R + +++E R +RD+ R+ R+R R RDR R++
Sbjct: 1129 QHPRAEQREQERAVREQWAEREREMERRERTRSE-REWDRDKVREGPRSRSRSRDRRRKE 1187
Query: 67 QTDREGERQRERERDRDR------------------------------QRETER-ERDKE 95
+ + ++ ++E+ ++ Q+E ER ER KE
Sbjct: 1188 RAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKE 1247
Query: 96 RETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETG 155
RE R E + E QK++E+E ER R+R+ E++K RE RER+R+ ERERE
Sbjct: 1248 REK-RRKEQEEEEQKEREKEAERERNRQLEREKR--------REHSRERDRERERERE-- 1296
Query: 156 RERKTEDRHRERERERKRERER---KRETKERERHT 188
R+R DR RER+RER RER+R KR ++ R R T
Sbjct: 1297 RDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRST 1332
Score = 98.2 bits (243), Expect = 5e-21
Identities = 69/223 (30%), Positives = 110/223 (49%), Gaps = 47/223 (21%)
Query: 32 DRAKESKTEDR-----------------HSERDRQRDRERNRERDRDREREKQTDREGER 74
DR E+KTE++ R QR++ER R++ ERE++ +R
Sbjct: 1101 DRPSETKTEEQGIPRPLHPPPPPPVQPPQHPRAEQREQER-AVREQWAEREREMERRERT 1159
Query: 75 QRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRE- 133
+ ERE DRD+ RE R R + R+ R +ER K KE++ E+ + E ++ +
Sbjct: 1160 RSEREWDRDKVREGPRSRSRSRDRRR-----KERAKSKEKKSEKKEKAQEEPPAKLLDDL 1214
Query: 134 ---------------------RQTDRETDRERERQAERERETGRERKTEDRHRERERERK 172
++ +R +ER+ R+ + E+K ++ ERER R+
Sbjct: 1215 FRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQ 1274
Query: 173 RERERKRE-TKERERHTDMERERQR-ETDRKRDRQRESERERD 213
ERE++RE ++ER+R + ERER R + DR R+R RE RERD
Sbjct: 1275 LEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERD 1317
Score = 77.8 bits (190), Expect = 6e-15
Identities = 58/182 (31%), Positives = 91/182 (50%), Gaps = 50/182 (27%)
Query: 19 RQRERRRETDRERDRAKESKTEDRHSERDR------------------------------ 48
R R+RRR +ER ++KE K+E + ++
Sbjct: 1179 RSRDRRR---KERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIV 1235
Query: 49 QRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRER 108
Q++ ER ER ++RE+ ++ ++E E Q+ERE++ +R+R + ER+K RE R E DRER
Sbjct: 1236 QKEAER-AERAKEREKRRK-EQEEEEQKEREKEAERERNRQLEREKRREHSR--ERDRER 1291
Query: 109 QKQKEREM-ERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRER 167
++++ER+ +R RDRER DRE RER+R+ + R R T R R
Sbjct: 1292 ERERERDRGDRDRDRER------------DRERGRERDRRDTKRHSRSRSRSTPVRDRGG 1339
Query: 168 ER 169
R
Sbjct: 1340 RR 1341
Score = 56.6 bits (135), Expect = 2e-08
Identities = 45/186 (24%), Positives = 80/186 (43%), Gaps = 10/186 (5%)
Query: 36 ESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKE 95
+S E E R R+ + + + + + R+GER+ R R + +E + E
Sbjct: 188 QSSLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAE 247
Query: 96 RETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERE-RET 154
E D+ T + R + + E E+++E E + D E + RE +E +E
Sbjct: 248 EEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEE 307
Query: 155 GRE---RKTEDRHRERERERKRERE------RKRETKERERHTDMERERQRETDRKRDRQ 205
G E K E+ ER + R +E+E R ++E R + + R++Q + +
Sbjct: 308 GEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPL 367
Query: 206 RESERE 211
E ERE
Sbjct: 368 EEEERE 373
Score = 52.8 bits (125), Expect = 2e-07
Identities = 56/204 (27%), Positives = 83/204 (40%), Gaps = 29/204 (14%)
Query: 26 ETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDR--- 82
E R R S +E++ + D ++ R+ R R R+ EG + E E D+
Sbjct: 197 ELSRHSPRKSSSISEEK-GDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETP 255
Query: 83 --------DRQRETERER---DKERETDRHTETDRERQKQKEREM-----ERVRDREREK 126
DR +TE E ++E E D E D E QK +E + E + R K
Sbjct: 256 SRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVK 315
Query: 127 QKEMGRERQTDRETDRE-RERQAERERETGRERKTEDRHRERERERK-------RERERK 178
+EM ER R ++E ER R RK+ +++E+E K ERE K
Sbjct: 316 PEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIK 375
Query: 179 RETKERERHTDMERERQRETDRKR 202
+E+ R E DRK+
Sbjct: 376 SSQGLKEKSKSPSPPRLTE-DRKK 398
Score = 52.8 bits (125), Expect = 2e-07
Identities = 49/169 (28%), Positives = 73/169 (43%), Gaps = 10/169 (5%)
Query: 19 RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRER 78
R+ ERR R+ AK S+ E + Q RN DR + T+ E E + E
Sbjct: 222 RKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLK--TEEEEEEEEEE 279
Query: 79 ERDRDRQRETERERDKERETDRHTETDRE-----RQKQKEREMERVRDREREKQKEMGRE 133
E D D + E + E K RE E E R K +E ER + R +E++
Sbjct: 280 EED-DEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGG 338
Query: 134 RQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETK 182
R T + + + A +++E +E KT E ERE K + K ++K
Sbjct: 339 RFTRSQEEARKSHLARQQQE--KEMKTTSPLEEEEREIKSSQGLKEKSK 385
Score = 41.6 bits (96), Expect = 5e-04
Identities = 40/175 (22%), Positives = 70/175 (40%), Gaps = 19/175 (10%)
Query: 5 TEGRHTHTETETMDR-QRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRE 63
+EG E E + R R DR +E + E+ E D + + + ++ R+
Sbjct: 240 SEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAP 299
Query: 64 REKQTDREGE---RQRERERDRDRQRETERERDKERETDRHTETDRERQK------QKER 114
K+ EGE R + E +R + +E++ R T + E +K Q+E+
Sbjct: 300 ILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEK 359
Query: 115 EMERVRDREREKQ--------KEMGRERQTDRET-DRERERQAERERETGRERKT 160
EM+ E E++ KE + R T DR++ +T E +T
Sbjct: 360 EMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEET 414
Score = 28.5 bits (62), Expect = 4.4
Identities = 35/185 (18%), Positives = 60/185 (32%), Gaps = 9/185 (4%)
Query: 20 QRERRR--ETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRE 77
Q+E RR T R K+S R+R R D R R
Sbjct: 554 QKEGRRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPD----SSGSRSHSPLRS 609
Query: 78 RERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTD 137
++RD + R R + + R T R R + + R + + + R+ T
Sbjct: 610 KQRDVAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSAS--SNSRKSLSPGVSRDSSTS 667
Query: 138 -RETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQR 196
ET Q + + E + R + R + + E+H + +R
Sbjct: 668 YTETKDPSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQPESAEKHVTQRLQPER 727
Query: 197 ETDRK 201
+ +K
Sbjct: 728 GSPKK 732
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 103 bits (257), Expect = 1e-22
Identities = 65/177 (36%), Positives = 92/177 (51%), Gaps = 23/177 (12%)
Query: 6 EGRHTHTETETMD-RQRER----RRETDRERDRAKESKTEDRHSERDRQRDRERNRERDR 60
EG+ +T + RQRER +E E A+ +EDR ER+R R+ R R+ DR
Sbjct: 2072 EGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDR 2131
Query: 61 DREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVR 120
RE ++ D++ R +R R+R R+ ERE D+ +E DR RER + +ERE +R R
Sbjct: 2132 PREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDR----SRERSRNRERERDRRR 2187
Query: 121 DREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERER 177
DR DR RER+R R+RE GR+RK + +E R+ K E R
Sbjct: 2188 DR--------------DRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASR 2230
Score = 100 bits (250), Expect = 7e-22
Identities = 61/177 (34%), Positives = 93/177 (52%), Gaps = 10/177 (5%)
Query: 35 KESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERD- 93
+E K + ++ R RER +++ E + D +G +R R+R+R R RERD
Sbjct: 2071 REGKGHEYRNQTFEGRQRERFDVGPKEKPLE-EPDAQGRASEDRRRERERGRNWSRERDW 2129
Query: 94 -KERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERER 152
+ RE DRH + D R + RE RDRERE R ++ DR +R R R+ ER+R
Sbjct: 2130 DRPREWDRHRDKDSSRDWDRNRERSANRDREREAD----RGKEWDRSRERSRNRERERDR 2185
Query: 153 ETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESE 209
R+R R RER+R++ R+RER R+ K+R + + R+ + E R D S+
Sbjct: 2186 RRDRDRS---RSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASDAGTASQ 2239
Score = 92.0 bits (227), Expect = 3e-19
Identities = 55/144 (38%), Positives = 82/144 (56%), Gaps = 10/144 (6%)
Query: 74 RQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRE 133
RQRER +++ E E + DR R++++ R R RD +R ++ + R+
Sbjct: 2086 RQRERFDVGPKEKPLE-----EPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRD 2140
Query: 134 RQTDRETDRERERQAERERETGRERKTE-DRHRERERERKRERERKRE---TKERERHTD 189
+ + R+ DR RER A R+RE +R E DR RER R R+RER+R+R+ ++ RER D
Sbjct: 2141 KDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRD 2200
Query: 190 MERERQRETDRKRDRQRESERERD 213
R+R+R DRK DR + E RD
Sbjct: 2201 KARDRERGRDRK-DRSKSKESARD 2223
Score = 47.8 bits (112), Expect = 7e-06
Identities = 25/64 (39%), Positives = 40/64 (62%), Gaps = 8/64 (12%)
Query: 18 DRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRE 77
+R+RER R DR+R R++E +RD+ RDRER R+R +DR + K++ R+ + +
Sbjct: 2178 NRERERDRRRDRDRSRSRE-------RDRDKARDRERGRDR-KDRSKSKESARDPKPEAS 2229
Query: 78 RERD 81
R D
Sbjct: 2230 RASD 2233
Score = 44.7 bits (104), Expect = 6e-05
Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 11/92 (11%)
Query: 131 GRERQTDRETDRERER------QAERERETGRERKTEDRHRERERERKRERERKRE---T 181
G E + R+RER + E + R +EDR RE RER R R+R+
Sbjct: 2075 GHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRE--RERGRNWSRERDWDRP 2132
Query: 182 KERERHTDMERERQRETDRKRDRQRESERERD 213
+E +RH D + R + +R+R R+ ERE D
Sbjct: 2133 REWDRHRDKDSSRDWDRNRERSANRDREREAD 2164
Score = 32.0 bits (71), Expect = 0.40
Identities = 31/133 (23%), Positives = 53/133 (39%), Gaps = 4/133 (3%)
Query: 31 RDRAKESKTEDRHSERDRQRDRERNRER---DRDREREKQTDREGERQRERERDRDRQRE 87
+D+A E + +DR + + + D ER + +R R E + E E D + E
Sbjct: 1372 KDKALEEEEDDRPYDPEEEYDPERAFDTQLVERGRRHEVERAPEAAAAEREEVAYDPEDE 1431
Query: 88 TERERDKERETDRHTETDRE-RQKQKEREMERVRDREREKQKEMGRERQTDRETDRERER 146
T E K D + R+ ER E V E + + + E++R
Sbjct: 1432 TILEEAKVTVDDLPNRMCADVRRNSVERPAEPVAGAATPSLVEQQKMLEELNKQIEEQKR 1491
Query: 147 QAERERETGRERK 159
Q E + E R+++
Sbjct: 1492 QLEEQEEALRQQR 1504
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 103 bits (256), Expect = 1e-22
Identities = 64/232 (27%), Positives = 119/232 (51%), Gaps = 22/232 (9%)
Query: 2 ESKTEGRHTHTETETMDRQRERR----RETDRERDRAKESKTEDRHSERDRQRDRERNRE 57
E K +E+ ++E++ + +ERD + S+ +D++ + ++R + ++R
Sbjct: 403 ERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRS 462
Query: 58 RDRDREREKQTDREGERQRE-RERDRDRQRETERERDKERETD-RHTETDRERQKQKERE 115
+ +++ + K+ D + R E R R R + R+ E ++KE+++D + + +R R K+K ++
Sbjct: 463 KSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQ 522
Query: 116 ME-RVRDREREKQKEMGRERQT-DRETD----------RERERQAERERETGRERKTEDR 163
+E + + + K KE R Q+ RE D R RER R+R +T DR
Sbjct: 523 LESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDR 582
Query: 164 HRERERE----RKRERERKRETKERERHTDMERERQRETDRKRDRQRESERE 211
R R +E R++E R+ ++ RER T R R ++ R+R R SERE
Sbjct: 583 DRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSERE 634
Score = 89.7 bits (221), Expect = 2e-18
Identities = 58/206 (28%), Positives = 98/206 (47%), Gaps = 12/206 (5%)
Query: 1 MESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDR 60
M S+++GR E + + ++ +R R + K + E + +E D + +E++R R +
Sbjct: 485 MRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDR-RAQ 543
Query: 61 DREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKERE-MERV 119
R RE + R R+R R R+ R R + R DR +E + +E+E R
Sbjct: 544 SRSRECDITKGKHSYNSRTRERSRSRDRSR-RVRSRTHDRDRSRSKEYHRYREQEYRRRG 602
Query: 120 RDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERE-----RERKRE 174
R R RE++ GR R DR R R +ERE R + D++R +E R+ E
Sbjct: 603 RSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNK---DKYRNQESKSSHRKENSE 659
Query: 175 RERKRETKERERHTDMERERQRETDR 200
E++ +K R+ H R+++ DR
Sbjct: 660 SEKRMYSKSRD-HNSSNNSREKKADR 684
Score = 78.6 bits (192), Expect = 4e-15
Identities = 54/233 (23%), Positives = 103/233 (44%), Gaps = 24/233 (10%)
Query: 1 MESKTEGRHTHTETETMDRQRERR---------------RETDRERDRAKESKTEDRHSE 45
+ESK+ H H++++ DR+ + R R +R R R + + R +
Sbjct: 523 LESKSN-EHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHD 581
Query: 46 RDRQRDRERNRERDRD-REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTET 104
RDR R +E +R R+++ R R + RE R R +DR+R R ERE +
Sbjct: 582 RDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNK 641
Query: 105 DRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRH 164
D+ R ++ + R E +K M + + ++ RE++A+R++ + K +
Sbjct: 642 DKYRNQESKSSH---RKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQD 698
Query: 165 RERE----RERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
E + + ++ E+ R KE ++ E + E ++K D + + D
Sbjct: 699 NELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTDED 751
Score = 78.2 bits (191), Expect = 5e-15
Identities = 53/223 (23%), Positives = 106/223 (47%), Gaps = 17/223 (7%)
Query: 3 SKTEGRHTHTETETMDRQRERRRETDRE-RDRAKESK-TEDRHSERDRQRDRERNRERDR 60
S+++ + E+++ + + +E DR + R++E T+ +HS R R ER+R RDR
Sbjct: 514 SRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTR--ERSRSRDR 571
Query: 61 DREREKQTDREGERQRERERDRDRQRETE-RERDKERETDRHTETDRERQKQKEREMERV 119
R +T +R R R ++ R RE E R R + R +R T R R K + R
Sbjct: 572 SRRVRSRTH---DRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDS 628
Query: 120 RDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERER-- 177
R ERE+ + +++ ++E+ ++ + + + RE+K +R++
Sbjct: 629 RSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSP 688
Query: 178 ----KRETKERERHTDMERERQRETDR---KRDRQRESERERD 213
K+ +++ E + M + ++ E R +++ Q+ +E D
Sbjct: 689 FSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQEND 731
Score = 75.9 bits (185), Expect = 2e-14
Identities = 52/216 (24%), Positives = 105/216 (48%), Gaps = 19/216 (8%)
Query: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDR 62
S++ R +ET R+ + R R + E + SE + ++ +R+ R ++R
Sbjct: 345 SRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKER 404
Query: 63 EREKQTD-REGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121
K TD R R+ +++++ + + KER+ R++E D K K + +R +
Sbjct: 405 ---KITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKD---DKYKNKVKKRAKS 458
Query: 122 REREKQKEMGRERQTDRETDRERERQAERERETGR--------ERKTEDRHRERERERKR 173
+ R K KE + ++ D + +R E++ R R GR E++++ + +++ER R +
Sbjct: 459 KSRSKSKEKSKSKERDSKHNRNEEKRM-RSRSKGRDHENVKEKEKQSDSKGKDQERSRSK 517
Query: 174 ERERKRETKERERHTDMERERQRETDRKRDRQRESE 209
E+ ++ E+K E +E+ R R + R RE +
Sbjct: 518 EKSKQLESKSNEHDHSKSKEKDR---RAQSRSRECD 550
Score = 67.8 bits (164), Expect = 7e-12
Identities = 50/211 (23%), Positives = 92/211 (43%), Gaps = 15/211 (7%)
Query: 13 ETETMDRQRERRRETDRERD-------RAKESKTEDRHSERDRQRDRERNRERDRDRERE 65
E E +R+RER RE + R +++ + R +R R +R R RDR R
Sbjct: 296 EKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRR 355
Query: 66 KQTDREGERQRERERDRDRQRETERER----DKERETDRHTETDRERQKQKEREMERVRD 121
+T ++ +R + R R + ER DK E + E R + KER++ R+
Sbjct: 356 SETPPHWRQEMQRAQ---RMRVSSGERWIKGDKS-ELNEIKENQRSPVRVKERKITDHRN 411
Query: 122 REREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRET 181
++ +E++ +ER R E + K + + R + + R + +E+ +
Sbjct: 412 VSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSK 471
Query: 182 KERERHTDMERERQRETDRKRDRQRESERER 212
+ +H E +R R + RD + E+E+
Sbjct: 472 ERDSKHNRNEEKRMRSRSKGRDHENVKEKEK 502
Score = 57.0 bits (136), Expect = 1e-08
Identities = 37/187 (19%), Positives = 84/187 (44%), Gaps = 13/187 (6%)
Query: 35 KESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDK 94
K + E ++ ER+R+R+ + +R R G + + R R R R RD+
Sbjct: 293 KADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDR 352
Query: 95 ERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERET 154
R ++ +E Q+ + + + + E+ ++ R R +ER+ R
Sbjct: 353 FRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNV 412
Query: 155 GRERKTEDRHRERERERK--------RERERKRETKERERHTDMERERQRETDRKRDRQR 206
+E +R+ E+E+K +ER+ +R +++ +++ + ++R + R + +++
Sbjct: 413 -----SESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEK 467
Query: 207 ESERERD 213
+ERD
Sbjct: 468 SKSKERD 474
Score = 44.7 bits (104), Expect = 6e-05
Identities = 40/210 (19%), Positives = 91/210 (43%), Gaps = 28/210 (13%)
Query: 15 ETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGER 74
E + + + ++ E R + + S + S+ D D + + + + E T+ + ++
Sbjct: 176 ELIPKSKVKKEEKKRHKSSSSSSSSS---SDSDSSSDSQSSSDSS---DSESATEEKSKK 229
Query: 75 QRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD-------REREKQ 127
++++ R R+ + E+++ K+ + +E++ E + + + R + R ++
Sbjct: 230 RKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRK 289
Query: 128 KEMGRERQTDRETDRERERQ--------AERER-----ETGRERKTED--RHRERERERK 172
+ + + +RERER+ A +R +GR+ K R+R R R
Sbjct: 290 SPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRS 349
Query: 173 RERERKRETKERERHTDMERERQRETDRKR 202
R+R R+ ET R +R R + +R
Sbjct: 350 RDRFRRSETPPHWRQEMQRAQRMRVSSGER 379
Score = 40.8 bits (94), Expect = 9e-04
Identities = 35/178 (19%), Positives = 69/178 (38%), Gaps = 14/178 (7%)
Query: 46 RDRQRDRERNRERDRDREREKQTDREGERQRERERDR-DRQRETERERDKERETDRHTET 104
+ + + E+ R + +D + + D D + TE + K ++ R
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSR 239
Query: 105 DRERQKQKEREMERVRDREREKQKEMGRERQTDR--ETDRERERQAERERETGRERKTED 162
+++K+K ++ ++ E E + + + T R E E + + + + E
Sbjct: 240 KHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKER 299
Query: 163 RHRERERERK-----------RERERKRETKERERHTDMERERQRETDRKRDRQRESE 209
++RERERER+ + R + + + R R R RDR R SE
Sbjct: 300 KNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSE 357
Score = 37.4 bits (85), Expect = 0.010
Identities = 21/132 (15%), Positives = 59/132 (44%), Gaps = 2/132 (1%)
Query: 82 RDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETD 141
+ + ++ E++R K + + +D + + + D E +++ + ++ R+
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDS-SDSESATEEKSKKRKKKHRKNS 238
Query: 142 RERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRK 201
R+ +++ ++ +++ + +E E + + R E + + R+ + D K
Sbjct: 239 RKHKKEKKKRKKSKKSASSESEAENLEAQ-PQSTVRPEEIPPIPENRFLMRKSPPKADEK 297
Query: 202 RDRQRESERERD 213
+ RE ERER+
Sbjct: 298 ERKNRERERERE 309
>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
sapiens]
Length = 437
Score = 102 bits (254), Expect = 2e-22
Identities = 75/229 (32%), Positives = 113/229 (49%), Gaps = 29/229 (12%)
Query: 4 KTEGRHTHTETE---TMDRQRERRRETDRERDRAKESKTEDRHSERDR------------ 48
K +GR + E T+ R RR R + RHS RD
Sbjct: 168 KIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSP 227
Query: 49 --QRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDR 106
RDR+R+RER+R RER ++ D+E ER+R R RDR R+ + + ++ R +R + DR
Sbjct: 228 LPHRDRDRDRERER-RERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDR 286
Query: 107 ERQKQKEREMERVRDREREKQKEMGR--------ERQTDRETDRERERQAERERETGRER 158
+R+++ R ER R RERE+++E+ D D + + G E
Sbjct: 287 DRKRRSSRSRERAR-RERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEE 345
Query: 159 KTEDRHRERERERKRERERKRETKERERHTDMERER-QRETDRKRDRQR 206
K DR RER R + ERER+R+ ++R+R D E +R +R ++R RD R
Sbjct: 346 KGRDRDRERRRSHRSERERRRD-RDRDRDRDREHKRGERGSERGRDEAR 393
Score = 62.4 bits (150), Expect = 3e-10
Identities = 35/77 (45%), Positives = 48/77 (62%), Gaps = 4/77 (5%)
Query: 137 DRETDRERER-QAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQ 195
DR+ DRERER + RER+ RER+ R R R R++E +R + RER D +R+R+
Sbjct: 232 DRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERR--RSRERSKDKDRDRK 289
Query: 196 RETDRKRDRQRESERER 212
R + R R+R R ERER
Sbjct: 290 RRSSRSRERARR-ERER 305
Score = 57.8 bits (138), Expect = 7e-09
Identities = 41/127 (32%), Positives = 63/127 (49%), Gaps = 6/127 (4%)
Query: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRA---KESKTEDRHSERDRQRDRER-NRER 58
S+ + + + D+ R+R+R + R R+RA +E K E R D E +
Sbjct: 268 SRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPP 327
Query: 59 DRDREREKQTD-REGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREME 117
D E D +G ++ R+RDR+R+R ER++ R+ DR + DRE K+ ER E
Sbjct: 328 DDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDRE-HKRGERGSE 386
Query: 118 RVRDRER 124
R RD R
Sbjct: 387 RGRDEAR 393
Score = 40.0 bits (92), Expect = 0.001
Identities = 24/59 (40%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Query: 6 EGRHTHTETETMDR-QRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRE 63
+GR E R +RERRR+ DR+RDR +E K +R SER R R +D E
Sbjct: 346 KGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGGGQDNGLE 404
Score = 29.3 bits (64), Expect = 2.6
Identities = 17/67 (25%), Positives = 26/67 (38%)
Query: 6 EGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRERE 65
E R +H R R+R R+ DRE R + R R ++ E + R+
Sbjct: 353 ERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGGGQDNGLEGLGNDSRD 412
Query: 66 KQTDREG 72
+ EG
Sbjct: 413 MYMESEG 419
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 100 bits (249), Expect = 9e-22
Identities = 59/213 (27%), Positives = 98/213 (46%), Gaps = 7/213 (3%)
Query: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRE 63
+ E + + + R R R ++ RDR S++ + RDR R R N+ RD R
Sbjct: 384 RKESGRSQSGSPNKQRDHSRSRSPNKARDR---SRSRSPYKARDRSRSRSPNKARDCSRS 440
Query: 64 RE--KQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121
R K DR R + RD R R + RD+ R E D + +E + R
Sbjct: 441 RSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRS 500
Query: 122 REREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERK-RE 180
R K+++ + R + +E D R R +ER+ R+ ++ ++ R+R + R ER+ R+
Sbjct: 501 RSPSKERQCRQSRSSSKERDHRRSRSPSKERQR-RQSRSPNKERDRSQSRSPSEEREHRQ 559
Query: 181 TKERERHTDMERERQRETDRKRDRQRESERERD 213
++ + D R R +R+R + R S ERD
Sbjct: 560 SRSPSKERDRRRWRSPSKERERRQSRSSSEERD 592
Score = 98.6 bits (244), Expect = 3e-21
Identities = 62/212 (29%), Positives = 98/212 (46%), Gaps = 13/212 (6%)
Query: 9 HTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQT 68
H+ + + R R R R + RDR++ S++ ++ + R R + R+R R R K
Sbjct: 401 HSRSRSPNKARDRSRSRSPYKARDRSR-SRSPNKARDCSRSRSPYKARDRSRSRSPNKAR 459
Query: 69 DREGERQRERERDRDRQRETERERD--------KERETDRHTETDRERQKQKEREMERVR 120
D R + RDR R R +ERD KER+ R +ERQ ++ R + R
Sbjct: 460 DHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKER 519
Query: 121 DREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRE 180
D R + R+R+ R ++ER+R R RE + + R +ER+R+R R
Sbjct: 520 DHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHR-QSRSPSKERDRRRWRS---P 575
Query: 181 TKERERHTDMERERQRETDRKRDRQRESERER 212
+KERER +R+ R R ++S R
Sbjct: 576 SKERERRQSRSSSEERDHSRSRSPNKQSGYSR 607
Score = 95.1 bits (235), Expect = 4e-20
Identities = 58/213 (27%), Positives = 94/213 (44%), Gaps = 9/213 (4%)
Query: 6 EGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRERE 65
E H+H+ + + +R R + R + S++ + +RD R R N+ RDR R R
Sbjct: 362 ERSHSHSRSSSKERDH---RGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRS 418
Query: 66 --KQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRE 123
K DR R + RD R R + RD+ R + D R + + +R R R
Sbjct: 419 PYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRS 478
Query: 124 REKQKEMGRERQTDRETDRERERQAERERETGRER---KTEDRHRERERERKRERERKRE 180
K+++ + +E D R R +ER+ + R K D R R ++R+R + R
Sbjct: 479 PSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRS 538
Query: 181 -TKERERHTDMERERQRETDRKRDRQRESERER 212
KER+R +RE + R +E +R R
Sbjct: 539 PNKERDRSQSRSPSEEREHRQSRSPSKERDRRR 571
Score = 90.5 bits (223), Expect = 9e-19
Identities = 56/215 (26%), Positives = 92/215 (42%), Gaps = 6/215 (2%)
Query: 2 ESKTEGR---HTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRER 58
+S+T R H + + +R R + +ERD + S + + S R + + R+
Sbjct: 343 QSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDH-RGSSSPRKESGRSQSGSPNKQRDH 401
Query: 59 DRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMER 118
R R K DR R + RDR R R + RD R + DR R + + +
Sbjct: 402 SRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDH 461
Query: 119 VRDREREKQKEMGRERQTDRETDRERERQAERERETGRERK-TEDRHRERERERKRERER 177
R R K ++ R R +E D + +ER+ R R +++R + R +ER+
Sbjct: 462 SRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDH 521
Query: 178 KR-ETKERERHTDMERERQRETDRKRDRQRESERE 211
+R + +ER R +E DR + R ERE
Sbjct: 522 RRSRSPSKERQRRQSRSPNKERDRSQSRSPSEERE 556
Score = 85.1 bits (209), Expect = 4e-17
Identities = 57/215 (26%), Positives = 94/215 (43%), Gaps = 11/215 (5%)
Query: 9 HTHTETETMDRQRERRRETDRERDRAKE---SKTEDRHSERDRQRDRERNRERDRDRERE 65
H+ +++ R R R + R+ +KE S + ERD + +E R +
Sbjct: 335 HSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGS 394
Query: 66 --KQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRE 123
KQ D R + RDR R R + RD+ R + D R + + +R R R
Sbjct: 395 PNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRS 454
Query: 124 REKQKEMGRERQTDRETDRERERQAERER---ETGRERKTEDRHRERERERKRE-RERKR 179
K ++ R R ++ DR R R +ER + G K D R R ++R+ R+ +
Sbjct: 455 PNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRS 514
Query: 180 ETKERE--RHTDMERERQRETDRKRDRQRESERER 212
+KER+ R +ERQR R +++R+ + R
Sbjct: 515 SSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSR 549
Score = 82.0 bits (201), Expect = 3e-16
Identities = 49/212 (23%), Positives = 90/212 (42%), Gaps = 11/212 (5%)
Query: 7 GRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREK 66
GRH+ + + + + + + R R R S R+ ++R R+ ++RD
Sbjct: 327 GRHSQSRSHSKGKSQNQSRTPRRGR-----SHNWSRNPSKERSHSHSRSSSKERDHRGSS 381
Query: 67 QTDREGERQRE----RERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDR 122
+E R + ++RD R R + RD+ R + DR R + + + R R
Sbjct: 382 SPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSR 441
Query: 123 EREKQKEMGRERQTDRETDRERERQAERERETGRERK-TEDRHRERERERKRERERKRE- 180
K ++ R R ++ D R R + R+ R R +++R + +ER+ +R
Sbjct: 442 SPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSR 501
Query: 181 TKERERHTDMERERQRETDRKRDRQRESERER 212
+ +ER R +E D +R R ER+R
Sbjct: 502 SPSKERQCRQSRSSSKERDHRRSRSPSKERQR 533
Score = 77.0 bits (188), Expect = 1e-14
Identities = 59/237 (24%), Positives = 94/237 (39%), Gaps = 26/237 (10%)
Query: 2 ESKTEGR-HTHTETETMDRQRERRR-----ETDRERDRAKESKTEDRHSERDRQRDRERN 55
+ +T R +H+ R R R R + R SK + ++ R +R R N
Sbjct: 295 QKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHN 354
Query: 56 RERDRDRERE--------KQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRE 107
R+ +ER K+ D G +E R + ++RD R + DR
Sbjct: 355 WSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRS 414
Query: 108 RQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRER---KTEDRH 164
R + + +R R R K ++ R R + DR R R + R+ R R K DR
Sbjct: 415 RSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRS 474
Query: 165 RERERERKRERER-----KRETKERERHTDMERE--RQRETDRKRD--RQRESERER 212
R R ++R+ + K R R ER+ + R + ++RD R R +ER
Sbjct: 475 RSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKER 531
Score = 77.0 bits (188), Expect = 1e-14
Identities = 48/205 (23%), Positives = 86/205 (41%), Gaps = 5/205 (2%)
Query: 6 EGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRERE 65
E H + + + +RQ + R + +ERD + ER R++ R N+ERDR + R
Sbjct: 494 ERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPS---KERQRRQSRSPNKERDRSQSRS 550
Query: 66 KQTDREGERQRE--RERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRE 123
+RE + R +ERDR R R +ER++ + E D R + ++ R R
Sbjct: 551 PSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRA 610
Query: 124 REKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKE 183
K+K R R +E + + R + +E + + +R R + R +
Sbjct: 611 SSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSK 670
Query: 184 RERHTDMERERQRETDRKRDRQRES 208
H+ +T + D Q ++
Sbjct: 671 TSSHSPSTFPSGGQTLSQDDSQADA 695
Score = 74.3 bits (181), Expect = 7e-14
Identities = 50/219 (22%), Positives = 82/219 (37%), Gaps = 17/219 (7%)
Query: 7 GRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREK 66
G T + +R R R R RHS+ R + + +++ R +
Sbjct: 293 GSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQ---SRSHSKGKSQNQSRTPRR 349
Query: 67 QTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREK 126
R +ER R + +ERD + E+ R + ++ + R R K
Sbjct: 350 GRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNK 409
Query: 127 QKEMGRERQTDRETDRERERQAERERETGRER---KTEDRHRERERERKRERERKR---E 180
++ R R + DR R R + R+ R R K DR R R + R+ R R +
Sbjct: 410 ARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNK 469
Query: 181 TKERERHTDMERER--------QRETDRKRDRQRESERE 211
++R R +ER +E D +R R ER+
Sbjct: 470 ARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQ 508
Score = 71.6 bits (174), Expect = 5e-13
Identities = 41/174 (23%), Positives = 72/174 (41%), Gaps = 1/174 (0%)
Query: 6 EGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRERE 65
E H+ + + +R R R +ER + ++S++ + + R R + R+R + R
Sbjct: 482 ERDHSQLGSPSKERDHRRSRSPSKER-QCRQSRSSSKERDHRRSRSPSKERQRRQSRSPN 540
Query: 66 KQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRERE 125
K+ DR R ER+ + R +ERD+ R E +R + + E + R R
Sbjct: 541 KERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPN 600
Query: 126 KQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179
KQ R R + +E R R +E + R + + R + KR
Sbjct: 601 KQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKR 654
Score = 62.0 bits (149), Expect = 4e-10
Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 13/139 (9%)
Query: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDR 62
S E H + + + +RQR + R ++ERDR S++ ER+ ++ R ++ERDR R
Sbjct: 515 SSKERDHRRSRSPSKERQRRQSRSPNKERDR---SQSRSPSEEREHRQSRSPSKERDRRR 571
Query: 63 EREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDR 122
R +ER+R + R + ERD R + ++ R + +E R R
Sbjct: 572 WRSP----------SKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSR 621
Query: 123 EREKQKEMGRERQTDRETD 141
K+ + R + +E+D
Sbjct: 622 TPSKEGNHSQSRTSSKESD 640
Score = 52.0 bits (123), Expect = 4e-07
Identities = 50/235 (21%), Positives = 81/235 (34%), Gaps = 48/235 (20%)
Query: 24 RRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRD 83
R ++ + + K+ ++ S R R + ++R R R ++ R +R+
Sbjct: 253 REKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHS 312
Query: 84 RQRETERE--------------------RDKERETDRHTETDRERQKQKEREMERVRDRE 123
R R R+ +++ R R + R KER R
Sbjct: 313 RARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSS 372
Query: 124 RE----------------------KQKEMGRERQTDRETDRERERQAERERETGRER--- 158
+E KQ++ R R ++ DR R R + R+ R R
Sbjct: 373 KERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPN 432
Query: 159 KTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
K D R R + R+R R R + H+ R R R R R R +ERD
Sbjct: 433 KARDCSRSRSPYKARDRSRSRSPNKARDHS---RSRSPNKARDRSRSRSPSKERD 484
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 99.4 bits (246), Expect = 2e-21
Identities = 58/151 (38%), Positives = 96/151 (63%), Gaps = 11/151 (7%)
Query: 30 ERDRAKESKTEDRHSERDRQRDRER-NRERDRDREREKQTDREGERQRERERDRDRQRET 88
E R + ++TE H+ R+R+R+RER NR+R+R+RERE+ +RE RQRERER+R+ +R+
Sbjct: 386 ENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERE-RRQREREREREHERDK 444
Query: 89 ERERDKERETDRHTETDRERQKQKEREME-RVRDREREKQKEMGRER-QTDRETDRERER 146
ER+R KE E +RER K+ E++ + R RDRE+E++KE G+ + ++ + R+ E
Sbjct: 445 ERQRRKE-------EWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEP 497
Query: 147 QAERERETGRERKTEDRHRERERERKRERER 177
+ TG + K D ++ R K +++
Sbjct: 498 PKKEAATTGPQVKRADEWKDPWRRSKSPKKK 528
Score = 95.5 bits (236), Expect = 3e-20
Identities = 67/209 (32%), Positives = 100/209 (47%), Gaps = 28/209 (13%)
Query: 8 RHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQ 67
R +TETE RER RE +RE +RQR+RER RERDR+RER +
Sbjct: 389 RVQYTETEPYHNYRERERERERE----------------NRQRERERERERDRERERRQ- 431
Query: 68 TDREGERQRERERDRDRQR---ETERERDKERETDRHTETDRERQKQKEREMERVRDRER 124
RE ER+RE ERD++RQR E ERER K E DR DR+R+K++E+E + + R
Sbjct: 432 --REREREREHERDKERQRRKEEWERERAKRDEKDRQ-HRDRDREKEREKEKGKPKPRSP 488
Query: 125 EKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKER 184
+ + + T + ++A+ ++ R K+ + R R R++ +
Sbjct: 489 QPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASS 548
Query: 185 ERHTDMERERQRETD-----RKRDRQRES 208
++ R R + R R R S
Sbjct: 549 ASASNSSRSSSRSSSYSGSGSSRSRSRSS 577
Score = 87.0 bits (214), Expect = 1e-17
Identities = 61/167 (36%), Positives = 95/167 (56%), Gaps = 15/167 (8%)
Query: 56 RERDRDREREKQTDREGERQRERERDRDRQRETE-------RERDKERETDRHTETDRER 108
+E++ D E ++ T GE +RE +++ + R+ R+ E D + + + ER
Sbjct: 319 KEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYEIER 378
Query: 109 -QKQKEREMERVRDREREKQKEMGRERQTDRETD-RERERQAERERETGRERKTEDRHRE 166
+ + E RV+ E E RER+ +RE + R+RER+ ERER+ RER+ +R RE
Sbjct: 379 FWRGGQYENFRVQYTETEPYHNY-RERERERERENRQRERERERERDRERERRQRERERE 437
Query: 167 RERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
RE ER +ER+R++E ERER E++RQ RDR RE ERE++
Sbjct: 438 REHERDKERQRRKEEWERERAKRDEKDRQH-----RDRDREKEREKE 479
Score = 77.8 bits (190), Expect = 6e-15
Identities = 70/218 (32%), Positives = 100/218 (45%), Gaps = 33/218 (15%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHS---ERDRQRDRERNRER 58
ES E H + + +E D E R + ED E + RD R
Sbjct: 298 ESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPR 357
Query: 59 D-RDREREKQTDREGERQRER-------ERDRDRQRETE-------RERDKERETDRHTE 103
D RD E D + + ER E R + ETE RER++ERE
Sbjct: 358 DVRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERE------ 411
Query: 104 TDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDR 163
+Q+ERE ER RDRERE+++ RER+ +RE +R++ERQ R+ E RER D
Sbjct: 412 -----NRQRERERERERDRERERRQ---REREREREHERDKERQ-RRKEEWERERAKRDE 462
Query: 164 HRERERERKRERERKRETKERERHTDMERERQRETDRK 201
+ R+R RE+ER++E + + + RQ E +K
Sbjct: 463 KDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKK 500
Score = 76.6 bits (187), Expect = 1e-14
Identities = 55/212 (25%), Positives = 98/212 (46%), Gaps = 24/212 (11%)
Query: 3 SKTEGRHTHTETETMDRQRERR---RETDRERDRAKESKTEDRHSERDRQRDRERNRERD 59
++TE H + E E +R+RE R RE +RERDR +E + +R ER+ +RD+ER R ++
Sbjct: 393 TETEPYHNYRERER-ERERENRQRERERERERDRERERRQREREREREHERDKERQRRKE 451
Query: 60 R-DREREKQTDREGERQRERERDRDRQRETERERDKERE---TDRHTETDRERQKQKERE 115
+RER K+ +++ ++ R+RDR+++RE E+ + K R R E ++ +
Sbjct: 452 EWERERAKRDEKD---RQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQ 508
Query: 116 MERVRD------REREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRE--- 166
++R + R + +K++G R R R + + ++ R
Sbjct: 509 VKRADEWKDPWRRSKSPKKKLGVSVSPSRA--RRRRKTSASSASASNSSRSSSRSSSYSG 566
Query: 167 --RERERKRERERKRETKERERHTDMERERQR 196
R R R + RH+ R R
Sbjct: 567 SGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSR 598
Score = 35.0 bits (79), Expect = 0.047
Identities = 42/190 (22%), Positives = 73/190 (38%), Gaps = 18/190 (9%)
Query: 26 ETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQ 85
E + R + ED HS+ + + +++ D+D E + + E E D +
Sbjct: 49 EDEESAARGPSQEEEDNHSDEEDRASEPKSQ--DQDSEVNELSRGPTSSPCEEEGDEGEE 106
Query: 86 RETERERDK----ERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETD 141
T RD+ RE D H E D + ++ E V++ E EK E D
Sbjct: 107 DRTSDLRDEASSVTRELDEH-ELDYD-EEVPEEPAPAVQEDEAEK---------AGAEDD 155
Query: 142 RERERQAERER-ETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDR 200
E+ RE + G + E E +E+K+E + D+E ++
Sbjct: 156 EEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSD 215
Query: 201 KRDRQRESER 210
++ R R + R
Sbjct: 216 RKVRPRPTCR 225
Score = 29.3 bits (64), Expect = 2.6
Identities = 30/139 (21%), Positives = 60/139 (43%), Gaps = 8/139 (5%)
Query: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121
+E+ K +G ++ +R+RD Q + ++ + T ++ + ++ V
Sbjct: 754 KEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAH 813
Query: 122 RERE-----KQKEMG-RERQTDRETDRERERQAERERETGRERKTEDRHRE-RERERKRE 174
+E + K + G R+R + DR+ A+R T +R + DR R K E
Sbjct: 814 KEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPN-TSPDRGSRDRKSGGRLGSPKPE 872
Query: 175 RERKRETKERERHTDMERE 193
R+R + +K D +R+
Sbjct: 873 RQRGQNSKAPAAPADRKRQ 891
>gi|213385278 TNF receptor-associated factor 3 interacting protein 1
isoform 2 [Homo sapiens]
Length = 625
Score = 98.2 bits (243), Expect = 5e-21
Identities = 61/187 (32%), Positives = 102/187 (54%), Gaps = 23/187 (12%)
Query: 23 RRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDR 82
R +E D + R +ES+ +R +ER+ RDR ++ E + DR + RE+D+
Sbjct: 145 RSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR-----KPREKDK 199
Query: 83 DRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDR 142
D+ E+ KE +RH E +RER K + R D ER+K + +R+ D
Sbjct: 200 DK------EKAKENGGNRHREGERERAKARARP-----DNERQKDR-----GNRERDRDS 243
Query: 143 ERERQAERERETGRER-KTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRK 201
ER+++ ER+ E G+E+ + DR RER+R++ ++R+R+R K E D++RE+ RE D+
Sbjct: 244 ERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRR-VKNGEHSWDLDREKNREHDKP 302
Query: 202 RDRQRES 208
+ S
Sbjct: 303 EKKSASS 309
Score = 88.6 bits (218), Expect = 4e-18
Identities = 61/216 (28%), Positives = 102/216 (47%), Gaps = 22/216 (10%)
Query: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRER----NRERD 59
+ E H TE + R T R+R + +E K + + E+D+ +++ + NR R+
Sbjct: 155 REEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHRE 214
Query: 60 RDREREKQTDR-EGERQ-----RERERDRDRQRETERERDKERETDRHTETDRERQKQKE 113
+RER K R + ERQ RER+RD +R++ETER+ + +E +R + DRER + K
Sbjct: 215 GERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKG 274
Query: 114 REMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKT------EDRHRER 167
+DR+R + K DRE +RE ++ ++ +G K +D E
Sbjct: 275 ------KDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAET 328
Query: 168 ERERKRERERKRETKERERHTDMERERQRETDRKRD 203
E E + TK +R + E +D + D
Sbjct: 329 ETEISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGD 364
Score = 84.7 bits (208), Expect = 5e-17
Identities = 58/159 (36%), Positives = 85/159 (53%), Gaps = 8/159 (5%)
Query: 57 ERDRDREREKQTDREGERQRERERDRDRQ--RETERERDKERETDRHTETDRERQKQKER 114
E+ + R T R E + R+ + + + TE D E + +R T DR KQKE
Sbjct: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIK-ERSTSRDR---KQKEE 187
Query: 115 EMERVRDREREKQKEMGRERQTDRETDRERERQAERER-ETGRERKTEDRHRERERERKR 173
E + RE++K KE +E +R + ERER R R + R++ +R R+R+ ERK+
Sbjct: 188 LKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKK 247
Query: 174 ERERKRET-KERERHTDMERERQRETDRKRDRQRESERE 211
E ERK E KE+ER D +RER R+ + RDR+R E
Sbjct: 248 ETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGE 286
Score = 82.8 bits (203), Expect = 2e-16
Identities = 57/165 (34%), Positives = 88/165 (53%), Gaps = 9/165 (5%)
Query: 55 NRERDRDREREKQTDREGE-RQRERERDRDRQRETERERDKERETDRHTETDRERQKQKE 113
N+ D R +GE + R R ++ + + R++E ++TE DR + KE
Sbjct: 117 NKLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTE-DRGDAEIKE 175
Query: 114 REMERVRDRERE-KQKEMGRERQTDRETDRE----RERQAERERETGRERKTEDRHRER- 167
R R R ++ E K+ RE+ D+E +E R R+ ERER R R +R ++R
Sbjct: 176 RSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRG 235
Query: 168 ERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERER 212
RER R+ ERK+ET ER+ E+ER R+ DR+RDR + +R+R
Sbjct: 236 NRERDRDSERKKET-ERKSEGGKEKERLRDRDRERDRDKGKDRDR 279
Score = 81.3 bits (199), Expect = 6e-16
Identities = 60/205 (29%), Positives = 106/205 (51%), Gaps = 27/205 (13%)
Query: 2 ESKTEGRHTHTETETMDRQRERR--RETDRERDRAKESKTEDRHSERDRQR-------DR 52
+++ + R T + + + +E R RE D+++++AKE+ +RH E +R+R D
Sbjct: 170 DAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGG-NRHREGERERAKARARPDN 228
Query: 53 ER-----NRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRE 107
ER NRERDRD ER+K+T+R+ E +E+ER RDR D+ER+ D+ + DR
Sbjct: 229 ERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDR--------DRERDRDKGKDRDRR 280
Query: 108 RQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHR-E 166
R K E + R++ RE K E+++ + ++ +++ E +TE R
Sbjct: 281 RVKNGEHSWDLDREKNREHDKP---EKKSASSGEMSKKLSDGTFKDSKAETETEISTRAS 337
Query: 167 RERERKRERERKRETKERERHTDME 191
+ K + R + + E + +D E
Sbjct: 338 KSLTTKTSKRRSKNSVEGDSTSDAE 362
>gi|20070262 TNF receptor-associated factor 3 interacting protein 1
isoform 1 [Homo sapiens]
Length = 691
Score = 98.2 bits (243), Expect = 5e-21
Identities = 61/187 (32%), Positives = 102/187 (54%), Gaps = 23/187 (12%)
Query: 23 RRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDR 82
R +E D + R +ES+ +R +ER+ RDR ++ E + DR + RE+D+
Sbjct: 145 RSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR-----KPREKDK 199
Query: 83 DRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDR 142
D+ E+ KE +RH E +RER K + R D ER+K + +R+ D
Sbjct: 200 DK------EKAKENGGNRHREGERERAKARARP-----DNERQKDR-----GNRERDRDS 243
Query: 143 ERERQAERERETGRER-KTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRK 201
ER+++ ER+ E G+E+ + DR RER+R++ ++R+R+R K E D++RE+ RE D+
Sbjct: 244 ERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRR-VKNGEHSWDLDREKNREHDKP 302
Query: 202 RDRQRES 208
+ S
Sbjct: 303 EKKSASS 309
Score = 88.2 bits (217), Expect = 5e-18
Identities = 60/210 (28%), Positives = 101/210 (48%), Gaps = 22/210 (10%)
Query: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRER----NRERD 59
+ E H TE + R T R+R + +E K + + E+D+ +++ + NR R+
Sbjct: 155 REEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHRE 214
Query: 60 RDREREKQTDR-EGERQ-----RERERDRDRQRETERERDKERETDRHTETDRERQKQKE 113
+RER K R + ERQ RER+RD +R++ETER+ + +E +R + DRER + K
Sbjct: 215 GERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKG 274
Query: 114 REMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKT------EDRHRER 167
+DR+R + K DRE +RE ++ ++ +G K +D E
Sbjct: 275 ------KDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAET 328
Query: 168 ERERKRERERKRETKERERHTDMERERQRE 197
E E + TK +R + E ++E
Sbjct: 329 ETEISTRASKSLTTKTSKRRSKNSVEGRKE 358
Score = 84.7 bits (208), Expect = 5e-17
Identities = 58/159 (36%), Positives = 85/159 (53%), Gaps = 8/159 (5%)
Query: 57 ERDRDREREKQTDREGERQRERERDRDRQ--RETERERDKERETDRHTETDRERQKQKER 114
E+ + R T R E + R+ + + + TE D E + +R T DR KQKE
Sbjct: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIK-ERSTSRDR---KQKEE 187
Query: 115 EMERVRDREREKQKEMGRERQTDRETDRERERQAERER-ETGRERKTEDRHRERERERKR 173
E + RE++K KE +E +R + ERER R R + R++ +R R+R+ ERK+
Sbjct: 188 LKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKK 247
Query: 174 ERERKRET-KERERHTDMERERQRETDRKRDRQRESERE 211
E ERK E KE+ER D +RER R+ + RDR+R E
Sbjct: 248 ETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGE 286
Score = 80.5 bits (197), Expect = 1e-15
Identities = 60/198 (30%), Positives = 99/198 (50%), Gaps = 34/198 (17%)
Query: 2 ESKTEGRHTHTETETMDRQRERR--RETDRERDRAKESKTEDRHSERDRQR-------DR 52
+++ + R T + + + +E R RE D+++++AKE+ +RH E +R+R D
Sbjct: 170 DAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGG-NRHREGERERAKARARPDN 228
Query: 53 ER-----NRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRE 107
ER NRERDRD ER+K+T+R+ E +E+ER RDR D+ER+ D+ + DR
Sbjct: 229 ERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDR--------DRERDRDKGKDRDRR 280
Query: 108 RQKQKEREMERVRDREREKQK---------EMGRERQ--TDRETDRERERQAERERETGR 156
R K E + R++ RE K EM ++ T +++ E E +
Sbjct: 281 RVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSL 340
Query: 157 ERKTEDRHRERERERKRE 174
KT R + E ++E
Sbjct: 341 TTKTSKRRSKNSVEGRKE 358
Score = 72.4 bits (176), Expect = 3e-13
Identities = 56/166 (33%), Positives = 84/166 (50%), Gaps = 17/166 (10%)
Query: 55 NRERDRDREREKQTDREGE-RQRERERDRDRQRETERERDKERETDRHTETDRERQKQKE 113
N+ D R +GE + R R ++ + + R++E ++TE DR + KE
Sbjct: 117 NKLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTE-DRGDAEIKE 175
Query: 114 REMERVRDRERE-KQKEMGRERQTDRETDRE----RERQAERERETGRERKTEDRHRER- 167
R R R ++ E K+ RE+ D+E +E R R+ ERER R R +R ++R
Sbjct: 176 RSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRG 235
Query: 168 ERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
RER R+ ERK+ET ER+ E+ER R+ DR ER+RD
Sbjct: 236 NRERDRDSERKKET-ERKSEGGKEKERLRDRDR--------ERDRD 272
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 96.7 bits (239), Expect = 1e-20
Identities = 66/208 (31%), Positives = 101/208 (48%), Gaps = 17/208 (8%)
Query: 19 RQRERRRETDRERDRA---KESKTEDRHSERDRQRDRERNRERDRDREREKQTDREG-ER 74
R R R R R R+ K SK D R R RDR R R R RD+ R + DR+ R
Sbjct: 11 RSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRR 70
Query: 75 QRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRER 134
R RERDR R+R R RD+ R R + R R + ++ +R R K+K G E
Sbjct: 71 SRSRERDRSRERRRSRSRDRRRSRSR-SRGRRSRSSSPGNKSKKTENRSRSKEKTDGGES 129
Query: 135 QTDRETDRERERQAERERETGR--ERKTEDRHRERER--ERKRERERKRE-------TKE 183
+++ D++ +++ E+E++ G + K E+ R+R+ E+ RE +RK+ KE
Sbjct: 130 SKEKKKDKD-DKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKE 188
Query: 184 RERHTDMERERQRETDRKRDRQRESERE 211
E ++ + D D E+E+E
Sbjct: 189 IEEMKQGKKWSLEDDDDDEDDPAEAEKE 216
Score = 93.6 bits (231), Expect = 1e-19
Identities = 61/179 (34%), Positives = 92/179 (51%), Gaps = 17/179 (9%)
Query: 40 EDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETD 99
E RH R R R R+ R R R + + G+ +R R RDRDR+RE R RDK R
Sbjct: 4 ESRHY-RKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62
Query: 100 RHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERK 159
R DR+R + R R RDR RE+++ R+R+ R R R R++ + +K
Sbjct: 63 R----DRKRLR---RSRSRERDRSRERRRSRSRDRR--RSRSRSRGRRSRSSSPGNKSKK 113
Query: 160 TEDRHRERER----ERKRERERKRETKERERHTD---MERERQRETDRKRDRQRESERE 211
TE+R R +E+ E +E+++ ++ KE E+ D ++ + E RKR + E RE
Sbjct: 114 TENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWRE 172
Score = 86.7 bits (213), Expect = 1e-17
Identities = 60/198 (30%), Positives = 104/198 (52%), Gaps = 16/198 (8%)
Query: 18 DRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRE 77
D +R R R+ DR R+R++ S+ + R RDR+R R R+R R+RDR RE++ R +R+R
Sbjct: 36 DDRRSRSRDRDRRRERSR-SRDKRRSRSRDRKRLR-RSRSRERDRSRERRRSRSRDRRRS 93
Query: 78 RERDRDRQRETERERDKERETDRHTETDR-----ERQKQKEREMERVRDREREKQKEMGR 132
R R R R+ + +K ++T+ + + E K+K+++ + D+E EK+K+ G
Sbjct: 94 RSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKD---DKEDEKEKDAGN 150
Query: 133 ERQTDRETD-RERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDME 191
Q E + R+R+ + E+ RE R++ E+ E K+E E ++ K+ D +
Sbjct: 151 FDQNKLEEEMRKRKERVEKWREEQRKKAMEN-----IGELKKEIEEMKQGKKWSLEDDDD 205
Query: 192 RERQRETDRKRDRQRESE 209
E K + E E
Sbjct: 206 DEDDPAEAEKEGNEMEGE 223
Score = 79.7 bits (195), Expect = 2e-15
Identities = 48/184 (26%), Positives = 83/184 (45%), Gaps = 4/184 (2%)
Query: 31 RDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETER 90
R K S + R R R R R + D R + DR+ R+R R RD+ R R +R
Sbjct: 6 RHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDR 65
Query: 91 E---RDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQ 147
+ R + RE DR E R R + + R R R R R + G + + R +E+
Sbjct: 66 KRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGR-RSRSSSPGNKSKKTENRSRSKEKT 124
Query: 148 AERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRE 207
E +++ +D+ E+E++ + K E + R+R +E+ R+ + + + E
Sbjct: 125 DGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGE 184
Query: 208 SERE 211
++E
Sbjct: 185 LKKE 188
Score = 67.0 bits (162), Expect = 1e-11
Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 15/148 (10%)
Query: 78 RERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTD 137
RE R+R R R R R R ++ R R RDR RE+ + R+++
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSR--SRDKRRS 60
Query: 138 RETDRER-ERQAERERETGRERKTEDRHRERERERKRERERK----------RETKERER 186
R DR+R R RER+ RER+ R R+R R R R R R+ ++T+ R R
Sbjct: 61 RSRDRKRLRRSRSRERDRSRERR-RSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSR 119
Query: 187 HTDMERERQRETDRKRDR-QRESERERD 213
+ + ++K+D+ +E E+E+D
Sbjct: 120 SKEKTDGGESSKEKKKDKDDKEDEKEKD 147
Score = 64.7 bits (156), Expect = 6e-11
Identities = 45/185 (24%), Positives = 91/185 (49%), Gaps = 18/185 (9%)
Query: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDR 62
S+ R + + DR RERRR R+R R++ S++ R S ++ + E +R
Sbjct: 62 SRDRKRLRRSRSRERDRSRERRRSRSRDRRRSR-SRSRGRRSRSSSPGNKSKKTE---NR 117
Query: 63 EREKQTDREGERQRERERDRDRQRETERERD---------KERETDRHTETDRERQKQKE 113
R K+ GE +E+++D+D +E E+E+D +E R ++ R++Q++
Sbjct: 118 SRSKEKTDGGESSKEKKKDKD-DKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRK 176
Query: 114 REMERVRDREREKQKEMGRERQTDRETDRERERQAERERE----TGRERKTEDRHRERER 169
+ ME + + ++E ++ ++ + + D + + AE E+E G E D + E +
Sbjct: 177 KAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVK 236
Query: 170 ERKRE 174
E ++
Sbjct: 237 EEVKK 241
Score = 36.2 bits (82), Expect = 0.021
Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 155 GRERKTEDRHRERERERKRERERKRETKE-RERHTDMERERQRETDRKRDRQRESERER 212
GRE + R R R R R R R + R + D R R R+ DR+R+R R ++ R
Sbjct: 2 GRESR-HYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRR 59
Score = 31.6 bits (70), Expect = 0.52
Identities = 27/130 (20%), Positives = 61/130 (46%), Gaps = 15/130 (11%)
Query: 2 ESKTEGRHTHTET--ETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERD 59
+ KT+G + E + D++ E+ K++ D++ + R R+ E+
Sbjct: 121 KEKTDGGESSKEKKKDKDDKEDEKE----------KDAGNFDQNKLEEEMRKRKERVEKW 170
Query: 60 RDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERV 119
R+ +R+K + GE ++E E + ++ + + D + D E ++E + + E++ +
Sbjct: 171 REEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDE--DDPAEAEKEGNEMEGEELDPL 228
Query: 120 RDREREKQKE 129
D E+ KE
Sbjct: 229 -DAYMEEVKE 237
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 95.1 bits (235), Expect = 4e-20
Identities = 70/229 (30%), Positives = 115/229 (50%), Gaps = 40/229 (17%)
Query: 20 QRERRRETDRERDRAKESKTE-DRHSERDRQRDRERNRERDRDREREKQTDREGERQRER 78
+R+R R DRERDR ++ K+ + +R R RDR R R R R R K +RE R +ER
Sbjct: 19 ERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERE-RRHKER 77
Query: 79 ERDRDRQRETERERDKERETDRHT-ETDRERQ-----KQKEREMERVRDREREKQKEMG- 131
ERD++R R ++D++R+ D H + DR+R + K+ + + RD +++++ E G
Sbjct: 78 ERDKERDRN---KKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDEHGD 134
Query: 132 ----------RERQTDRETDRERERQ------AERERET--GRERKTEDRHRERERERKR 173
E ++ + E E + AERE E R+++ E+R R E ERK+
Sbjct: 135 KKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKK 194
Query: 174 ER----------ERKRETKERERHTDMERERQRETDRKRDRQRESERER 212
+ E +E + RER MERE D + ++ E+++
Sbjct: 195 RKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDK 243
Score = 89.4 bits (220), Expect = 2e-18
Identities = 62/221 (28%), Positives = 113/221 (51%), Gaps = 33/221 (14%)
Query: 22 ERRRETDRERDRAKESKTEDRHSERDRQR------DRERNRERD--------RDREREKQ 67
++ R+ ++ K S+T DR +RDR R DR+R+R RD R R R K
Sbjct: 8 KKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKS 67
Query: 68 TDREGERQRERERDRDRQRETERERDKERETDRH-TETDRERQ-----KQKEREMERVRD 121
+RE R +ERERD++R R ++D++R+ D H + DR+R + K+ + + RD
Sbjct: 68 AERE-RRHKERERDKERDR---NKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRD 123
Query: 122 REREKQKEMGRERQTDRETDRER---ERQAERERE------TGRERKTEDRHRERERERK 172
+++++ E G ++ + E +++AE E E + ER+ E R ++ +
Sbjct: 124 SKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEE 183
Query: 173 RERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
R+R + E K+R++ D+ R+ + + R+R ER+
Sbjct: 184 RQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERE 224
Score = 87.8 bits (216), Expect = 6e-18
Identities = 66/237 (27%), Positives = 119/237 (50%), Gaps = 38/237 (16%)
Query: 8 RHTHTETETMDRQRERRRETDRERDR-AKESKTEDRHSERDRQRDRERNRERDRDREREK 66
R E R R RE DR+RDR + SK RH RDR+R R+R R R + E+
Sbjct: 11 RDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAER 70
Query: 67 QTDREGERQRERERDR---DRQRETE---RERDKERET-------------DRHTETDRE 107
+ R ER+R++ERDR DR R+ + R++D++R + DR ++ D E
Sbjct: 71 ER-RHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKDEE 129
Query: 108 ------RQKQKEREMERVRDREREKQKEMGRER---QTDRETDRERERQ---AERERETG 155
+ K + +E + +++ +++ + + + +RE + + RQ ER+R
Sbjct: 130 DEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLE 189
Query: 156 RERKTEDRHRERERE-----RKRERERKRETKERERHTDMERERQRETDRKRDRQRE 207
ERK + ++ R+ ++RER +RE ERE + + + E +++ ++D+ +E
Sbjct: 190 EERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDKSKE 246
Score = 75.5 bits (184), Expect = 3e-14
Identities = 44/136 (32%), Positives = 73/136 (53%), Gaps = 7/136 (5%)
Query: 72 GERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMG 131
GE +++RD +E ER + R DR + DR+R+ ++ +R R R+R +
Sbjct: 3 GELADKKDRDASPSKE---ERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRS 59
Query: 132 RERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDME 191
R R + +RER R ERER+ R+R +DR R+++ R R+++RKR + R D +
Sbjct: 60 RSRSRSKSAERER-RHKERERDKERDRNKKDRDRDKDGHR-RDKDRKRSSLSPGRGKDFK 117
Query: 192 RERQRETDRKRDRQRE 207
+ R D K+D + E
Sbjct: 118 SRKDR--DSKKDEEDE 131
Score = 72.4 bits (176), Expect = 3e-13
Identities = 61/218 (27%), Positives = 106/218 (48%), Gaps = 24/218 (11%)
Query: 3 SKTEGRHTHTETETMDRQRERRRETDR---ERDRAKESKTEDRHSERDR---QRDRERNR 56
S++ R E E ++RER +E DR +RDR K+ D+ +R R ++
Sbjct: 59 SRSRSRSKSAERERRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKS 118
Query: 57 ERDRDREREKQTDREGERQ--------RERERDRDRQRETERERDKERETDRHTETDRER 108
+DRD +++++ D G+++ E + + E E + + +R E + R
Sbjct: 119 RKDRDSKKDEE-DEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRR 177
Query: 109 QKQKEREMERVRDREREKQK---EMGRERQTDRETDRERERQAERERET-GRERKTEDRH 164
Q++ E E +R+ + ER+K+K ++GR+ D + RER+ ERET G E ++
Sbjct: 178 QQEVE-ERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNE---DEEG 233
Query: 165 RERERERKRERERKRETKERERHTDMERERQRE-TDRK 201
R++ RE K + + KER +R R R DRK
Sbjct: 234 RQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRK 271
Score = 69.3 bits (168), Expect = 2e-12
Identities = 39/127 (30%), Positives = 68/127 (53%), Gaps = 10/127 (7%)
Query: 93 DKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERER 152
DK+ ++ +R+R + +RE +R RDR+ K+ R R DR R R R +
Sbjct: 7 DKKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSK 66
Query: 153 ETGRERKTEDRHRERERERKRERERKRETKERERH-TDMERERQ-----RETDRKRDRQR 206
RER RH+ERER+++R+R +K ++++ H D +R+R R D K + R
Sbjct: 67 SAERER----RHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDR 122
Query: 207 ESERERD 213
+S+++ +
Sbjct: 123 DSKKDEE 129
Score = 58.5 bits (140), Expect = 4e-09
Identities = 74/313 (23%), Positives = 124/313 (39%), Gaps = 126/313 (40%)
Query: 19 RQRERRR--ETDRERDRAKESKTEDRHSERDRQRDRERNRE----------RDRDREREK 66
R R+RRR R R R+K ++ E RH ER+R ++R+RN++ RD+DR+R
Sbjct: 48 RSRDRRRGGSRSRSRSRSKSAERERRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSS 107
Query: 67 QTDREGERQRERERDRDRQRETERERDKER-----------------------------E 97
+ G+ + R +DRD +++ E E ++ +
Sbjct: 108 LSPGRGKDFKSR-KDRDSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSK 166
Query: 98 TDRHTETDRERQKQKEREMERVRDREREKQKE---MGR------------------ERQT 136
+R E + RQ++ E E +R+ + ER+K+K+ +GR ER+T
Sbjct: 167 AEREAEALKRRQQEVE-ERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERET 225
Query: 137 D------------RETDRERERQAERERETG------RERKTEDR--------------- 163
+ E D+ +E A +ER G R R DR
Sbjct: 226 NGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDASEDTSID 285
Query: 164 ----HRERE---------------RERKRERER-------KRETKERERHTDMERERQRE 197
++ER +++KRE+ R KR T E + + E R R+
Sbjct: 286 YNPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEK---EQEEARLRK 342
Query: 198 TDRKRDRQRESER 210
+K +QR +R
Sbjct: 343 LRKKEAKQRWDDR 355
Score = 56.2 bits (134), Expect = 2e-08
Identities = 51/212 (24%), Positives = 92/212 (43%), Gaps = 19/212 (8%)
Query: 13 ETETMDRQR----ERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQT 68
E E + R++ ER+R + ER + K+ + R D Q R R +RE
Sbjct: 170 EAEALKRRQQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNE 229
Query: 69 DREGERQRERERDRDRQRETERERD----KERETDRHTETDRERQKQKEREMERVRD--- 121
D EG ++ E+D+ ++ +ER K+R RH DR+ + + + D
Sbjct: 230 DEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLN-DRKFVFEWDASEDTSIDYNP 288
Query: 122 --REREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179
+ER + + +GR + +++ Q+ + +R+T + E+E++ R RK
Sbjct: 289 LYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLE-----EKEQEEARLRKL 343
Query: 180 ETKERERHTDMERERQRETDRKRDRQRESERE 211
KE ++ D Q++ D DR RE
Sbjct: 344 RKKEAKQRWDDRHWSQKKLDEMTDRDWRIFRE 375
Score = 53.9 bits (128), Expect = 1e-07
Identities = 36/99 (36%), Positives = 50/99 (50%), Gaps = 18/99 (18%)
Query: 115 EMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRE 174
E+ +DR+ KE ER+ R DRER+R +R+ ++RK RHR R+R R
Sbjct: 4 ELADKKDRDASPSKE---ERKRSRTPDRERDRDRDRKSSPSKDRK---RHRSRDRRRGGS 57
Query: 175 RERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
R R R R ERER R ++RE ++ERD
Sbjct: 58 RSRSRS-----RSKSAERER-------RHKERERDKERD 84
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 94.0 bits (232), Expect = 9e-20
Identities = 60/207 (28%), Positives = 106/207 (51%), Gaps = 32/207 (15%)
Query: 18 DRQRERRRET-DRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQR 76
D++ E+RR + R R R + + + RH R R R R R+ + R R R K R R
Sbjct: 240 DKKEEKRRHSRSRSRSRRRRTPSSSRH-RRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSR 298
Query: 77 ERERDRDRQRETERERDKERETD----------------RHTETDRERQKQKEREMERVR 120
ER R R R T + RDK++E R RER++++ R R
Sbjct: 299 ERGR---RSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSP 355
Query: 121 DREREKQKEMGR-------ERQTDRETDRERERQAERERETGRERKTEDRHRERERERKR 173
+ R ++++ R +++ ++ D+ER R ERER T +++K++D+ ++RER+ +
Sbjct: 356 KKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRD-ERERSTSKKKKSKDKEKDRERKSES 414
Query: 174 ERERKRETK---ERERHTDMERERQRE 197
+++ K+ T+ E E+ D E+E++ E
Sbjct: 415 DKDVKQVTRDYDEEEQGYDSEKEKKEE 441
Score = 84.0 bits (206), Expect = 9e-17
Identities = 52/205 (25%), Positives = 97/205 (47%), Gaps = 20/205 (9%)
Query: 25 RETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDR 84
+E + R +E+++ + +++ +R R R R R ++T +R R R R R
Sbjct: 217 KEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRR 276
Query: 85 QRETERERDKERETDRHTETDRERQKQKEREMERVRDRERE-KQKEMG-----------R 132
R R + + R RER + + R + RD+++E K+K+ R
Sbjct: 277 SHSKSRSRRRSKSPRRRRSHSRERGR-RSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARR 335
Query: 133 ERQTDRETDRERERQAERE----RETGRERKTEDRHRERERERKRERERKRETKERERHT 188
R RE R R R R R R+ R ++E+K++++++R ERER T
Sbjct: 336 SRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERST 395
Query: 189 DMERERQRETDRKRDRQRESERERD 213
++++ D+++DR+R+SE ++D
Sbjct: 396 S---KKKKSKDKEKDRERKSESDKD 417
Score = 77.4 bits (189), Expect = 8e-15
Identities = 41/182 (22%), Positives = 95/182 (52%), Gaps = 8/182 (4%)
Query: 8 RHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREK- 66
R +H+++ + R + RR R+R + S++ + ++ ++ D+E+ R + +
Sbjct: 275 RRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKE-DKEKKRSKTPPKSYSTA 333
Query: 67 QTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREK 126
+ R R+R R R R R ++ R +R+ R + + R +K+K+++ ++ R R+ +
Sbjct: 334 RRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSR-SPSPRRHKKEKKKDKDKERSRDERE 392
Query: 127 QKEMGRERQTDRETDRERERQAERE-----RETGRERKTEDRHRERERERKRERERKRET 181
+ +++ D+E DRER+ +++++ R+ E + D +E++ E+K +T
Sbjct: 393 RSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKT 452
Query: 182 KE 183
KE
Sbjct: 453 KE 454
Score = 73.6 bits (179), Expect = 1e-13
Identities = 50/198 (25%), Positives = 97/198 (48%), Gaps = 16/198 (8%)
Query: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDR 62
S+ GR + + ++T D+++E D+E+ R+K + R R RER R R R
Sbjct: 297 SRERGRRSRSTSKTRDKKKE-----DKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSG 351
Query: 63 EREKQTDREGERQRERERD-RDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121
R + R +R+ R R ++E ++++DKER D + +++K K++E +D
Sbjct: 352 TRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKE----KD 407
Query: 122 REREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRET 181
RER+ + + +Q R+ D E E+ ++ +E+K E + E + +E ++ T
Sbjct: 408 RERKSESDKD-VKQVTRDYDEE-----EQGYDSEKEKKEEKKPIETGSPKTKECSVEKGT 461
Query: 182 KERERHTDMERERQRETD 199
+ R + + + E D
Sbjct: 462 GDSLRESKVNGDDHHEED 479
Score = 32.7 bits (73), Expect = 0.24
Identities = 29/117 (24%), Positives = 57/117 (48%), Gaps = 15/117 (12%)
Query: 3 SKTEGRHTHTETETMDRQR---ERRRET-------DRERDRAKESKTEDRHSERDRQRDR 52
S + RH + + D++R ER R T D+E+DR ++S+++ + R D
Sbjct: 368 SPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDE 427
Query: 53 ERNRERDRDREREKQTDREG-ERQRERERDRDRQRET-ERERDKERETDRHTETDRE 107
E E+ D E+EK+ +++ E + ++ ++ T + R+ + D H E D +
Sbjct: 428 E---EQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDMD 481
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 92.4 bits (228), Expect = 2e-19
Identities = 51/201 (25%), Positives = 107/201 (53%), Gaps = 4/201 (1%)
Query: 13 ETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREG 72
+ + M Q ER E D ER R KE + + ++ + E+ RE + +E+EK+T +
Sbjct: 498 QEQKMWDQEERMWEQD-ERLREKEERMRE---QKKMWQQEEKMREEKKTQEQEKKTWDQE 553
Query: 73 ERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGR 132
E+ RE ER R+R+++ E + RE + + E+ +++E +M ++ +E++++M
Sbjct: 554 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWE 613
Query: 133 ERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMER 192
+ + E + E + Q + E +E K +++ + + ++ RE++ + +E+E +
Sbjct: 614 QEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 673
Query: 193 ERQRETDRKRDRQRESERERD 213
E+ RE + K Q E RE++
Sbjct: 674 EKMREQEEKMQGQEEKMREQE 694
Score = 89.0 bits (219), Expect = 3e-18
Identities = 58/205 (28%), Positives = 107/205 (52%), Gaps = 8/205 (3%)
Query: 10 THTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTD 69
T+T E M RQ E RE +E+ K+ + R ER R+++ + + ++ R +EK+
Sbjct: 229 TNTLQEEMWRQEEELRE--QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLR 286
Query: 70 REGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKE 129
+ + RE+E++ Q++ + ++ +E + E+ +++E +M R +R E++K+
Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 346
Query: 130 MGRERQTDRETDRERERQAERERE-TGRERKTEDRHRERERERKRERERKRETKERERHT 188
M + Q R+ + Q ER RE R R+ E + E+ ++ ER R+RE K RE
Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMRE--- 403
Query: 189 DMERERQRETDRKRDRQRESERERD 213
E E RE + K +Q E+ E++
Sbjct: 404 --EEETMREQEEKMQKQEENMWEQE 426
Score = 86.3 bits (212), Expect = 2e-17
Identities = 55/225 (24%), Positives = 114/225 (50%), Gaps = 13/225 (5%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETD-----------RERDRAKESKTEDRHSERDRQR 50
E + + + + E M RQ ER RE + R+ R +E + E R E++ +
Sbjct: 242 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE 301
Query: 51 DRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKE-RETDRHTETDRERQ 109
++ + ++ +E+E++ + E+ RE+E RQ E E++K+ RE ++ ER
Sbjct: 302 QKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM 361
Query: 110 KQKEREMERVRDREREKQKEMGR-ERQTDRETDRERERQAERERETGRERKTEDRHRERE 168
+++ + +R RE++K + E+ + E RERE++ E ET RE++ + + +E
Sbjct: 362 WEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 421
Query: 169 RERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
+ E+E +++ ++ E+E+ +E + K Q E R+++
Sbjct: 422 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 466
Score = 84.7 bits (208), Expect = 5e-17
Identities = 55/218 (25%), Positives = 114/218 (52%), Gaps = 17/218 (7%)
Query: 13 ETETMDRQRERRRETD---RERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTD 69
+ E M Q ER RE + RE+++ E + + + ER R+R+++ E + RE+E++
Sbjct: 357 QEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQ 416
Query: 70 REGERQRERERDRDRQRETERERDKERETDRHTETDRE--RQKQKEREMERVRDREREK- 126
++ E E+E +Q+ +++K E ++ E + + Q++K R+ E + +E++
Sbjct: 417 KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW 476
Query: 127 QKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERK-------- 178
++E RE++ E+ R E++ ER E R RE+E + ++K
Sbjct: 477 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKM 536
Query: 179 ---RETKERERHTDMERERQRETDRKRDRQRESERERD 213
++T+E+E+ T + E+ RE +R R+R+++ E +
Sbjct: 537 REEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 574
Score = 82.4 bits (202), Expect = 3e-16
Identities = 57/223 (25%), Positives = 111/223 (49%), Gaps = 27/223 (12%)
Query: 13 ETETMDRQRERRRETDRERDRAKESKTED---RHSERDRQRDRERNRERDRDREREKQTD 69
E E M Q E+ +E +R R+R K+ + E+ R E Q+ E E++ ++++
Sbjct: 377 EQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 436
Query: 70 REGERQRERERDRDRQRETERERDKERETDR---------HTETDRERQKQKEREMERVR 120
+ E+ E+E+ ++++ + + +K R+ + E RE++ Q + E++R
Sbjct: 437 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 496
Query: 121 DRER------EKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHR----ERERE 170
D+E+ E+ E + E RE+++ ++E + E+KT+++ + + E+
Sbjct: 497 DQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKM 556
Query: 171 RKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
R+ ER R+RE K RE E E RE + K Q E RE++
Sbjct: 557 REEERMREREKKMRE-----EEEMMREQEEKMQEQEEKMREQE 594
Score = 80.9 bits (198), Expect = 8e-16
Identities = 55/220 (25%), Positives = 114/220 (51%), Gaps = 8/220 (3%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
E E + E + Q E+ R+ + + K+ +++ E++ Q + + RD++
Sbjct: 440 EKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 499
Query: 62 REREKQTDR---EGERQRERERDRDRQRETERERDKERETDRHTETDRER--QKQKEREM 116
++ Q +R + ER RE+E Q++ ++ +K RE + E +++ Q++K RE
Sbjct: 500 QKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE 559
Query: 117 ERVRDRERE--KQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKR- 173
ER+R+RE++ +++EM RE++ + E+ R+ E + E+ E + E+E K
Sbjct: 560 ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 619
Query: 174 ERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
E+E + + +E+E + E+ +E + K Q E RE++
Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 659
Score = 80.9 bits (198), Expect = 8e-16
Identities = 53/195 (27%), Positives = 105/195 (53%), Gaps = 12/195 (6%)
Query: 15 ETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGER 74
E +R RE+++ +E +E KT+++ E+ E+ RE +R REREK+ E E
Sbjct: 518 EKEERMREQKKMWQQEEKMREEKKTQEQ--EKKTWDQEEKMREEERMREREKKMREEEEM 575
Query: 75 QRERERDRDRQRETERERDKE--RETDRHTETDRERQKQKEREMERVRDREREKQKEMGR 132
RE+E Q E RE++++ + ++ E + + +Q+E+ E+ + + ++Q+EM
Sbjct: 576 MREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMW 635
Query: 133 ERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMER 192
E++ E +E+E + + E RE++ + R +E + + + E+ R++E K + +
Sbjct: 636 EQE---EKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQG-----QE 687
Query: 193 ERQRETDRKRDRQRE 207
E+ RE + K Q E
Sbjct: 688 EKMREQEEKMRGQEE 702
Score = 80.5 bits (197), Expect = 1e-15
Identities = 50/212 (23%), Positives = 111/212 (52%), Gaps = 13/212 (6%)
Query: 13 ETETMDRQRERRRETDR-----ERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQ 67
+ + M RQ + R + D+ E+ R +E K D+ Q +R R +E +R RE++K
Sbjct: 471 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKE-ERMREQKKM 529
Query: 68 TDREGERQRERERDRDRQRET------ERERDKERETDRHTETDRERQKQKEREMERVRD 121
+E E+ RE ++ ++++++T RE ++ RE ++ + E +++E +M+ +
Sbjct: 530 WQQE-EKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 588
Query: 122 REREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRET 181
+ RE++++M + + +E + + Q E+ E E K +++ + ++ +E++ +
Sbjct: 589 KMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKM 648
Query: 182 KERERHTDMERERQRETDRKRDRQRESERERD 213
E+E + E+ RE + K Q E RE++
Sbjct: 649 WEQEEKMREQEEKMREQEEKMQGQEEKMREQE 680
Score = 77.4 bits (189), Expect = 8e-15
Identities = 57/205 (27%), Positives = 110/205 (53%), Gaps = 15/205 (7%)
Query: 21 RERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERE- 79
+E +R+ +R + + +T E RQ + R +E+ + R++E++ R+ ER RE+E
Sbjct: 211 KELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEK-KIRKQEEKMWRQEERLREQEG 269
Query: 80 --RDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREK---QKEMGRE- 133
R+++ + + +R +E+E + + R+++K RE E + EK Q+E RE
Sbjct: 270 KMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQ 329
Query: 134 -----RQTDRETDRERE-RQAERERETGRERKTEDRHRERER-ERKRERERKRETKERER 186
RQ +R ++E++ R+ E++ ER E R RE+ ER RE+E+ E +E+ +
Sbjct: 330 EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQ 389
Query: 187 HTDMERERQRETDRKRDRQRESERE 211
+ RER+++ + + RE E +
Sbjct: 390 EEERIREREKKMREEEETMREQEEK 414
Score = 77.4 bits (189), Expect = 8e-15
Identities = 55/214 (25%), Positives = 109/214 (50%), Gaps = 16/214 (7%)
Query: 4 KTEGRHTHTETETMDRQRERRRETD-RERDRAKESKTEDRHSERDRQRDRERN--RERDR 60
+ E R E E ++++E R + RE++ + + E + ++ R++E R+ +R
Sbjct: 280 RQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 339
Query: 61 DREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVR 120
E+EKQ Q ++ RD++ + + ER +E+E + Q++K +E ER+R
Sbjct: 340 LWEQEKQM----REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIR 395
Query: 121 DREREKQKEMGRERQTDRETDRERERQAE-----RERETGRERKTEDRHRERERERKRER 175
+RE K+M E +T RE + + ++Q E E+E ++R E + + E+E+ +E+
Sbjct: 396 ERE----KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 451
Query: 176 ERKRETKERERHTDMERERQRETDRKRDRQRESE 209
E K +E + E Q + ++++ RE E
Sbjct: 452 EEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 485
Score = 77.0 bits (188), Expect = 1e-14
Identities = 55/214 (25%), Positives = 110/214 (51%), Gaps = 14/214 (6%)
Query: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTED---RHSERDRQRDRERNRERDR 60
+ E + E +T D Q E+ RE +R R+R K+ + E+ R E Q E+ RE++
Sbjct: 537 REEKKTQEQEKKTWD-QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE- 594
Query: 61 DREREKQTDREGERQRERER--DRDRQRETERERDKERETDRHTETDRERQKQKEREMER 118
EK ++E + Q + E+ +++ + + E DK +E + E+ +++E +M
Sbjct: 595 ----EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWE 650
Query: 119 VRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERK 178
++ RE++++M RE++ + E+ R+ E + + E+ E + R +E K + +
Sbjct: 651 QEEKMREQEEKM-REQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEE 709
Query: 179 RETKERERHTDMERERQRETDRKRDRQRESERER 212
+ + E+ E R++E +R RD Q+E +ER
Sbjct: 710 KMWGQEEKMWGQEEMREKE-ERIRD-QKEKMQER 741
Score = 76.3 bits (186), Expect = 2e-14
Identities = 60/228 (26%), Positives = 113/228 (49%), Gaps = 17/228 (7%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
E + E R E + RE+ + + ++ E + + R E R ER E+++
Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 346
Query: 62 REREKQTDREGERQRERERDRDRQRETERERDKER-----ETDRHTETDRERQKQKEREM 116
++Q R+ E + + +R R++E ER R++E+ E + E RER+K+ E
Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKE-ERMREQEKMWEQEEKMQEEERIREREKKMREEE 405
Query: 117 ERVRDREREKQK-EMGRERQTDRETDRER-----ERQAERERETGRERK---TEDRHRER 167
E +R++E + QK E Q ++E ++R E+ E+E+ +E K E++ R++
Sbjct: 406 ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 465
Query: 168 ERERKRERERKRETKERERHTDM--ERERQRETDRKRDRQRESERERD 213
E +E++ R+ K RE+ M + E+ R+ ++K Q E E+D
Sbjct: 466 EEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQD 513
Score = 72.4 bits (176), Expect = 3e-13
Identities = 47/214 (21%), Positives = 112/214 (52%), Gaps = 4/214 (1%)
Query: 1 MESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDR 60
M+ + E E E ++ ++E E+++ +E + E + ++ RD+E +++
Sbjct: 415 MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQE-EKIWEQEEKIRDQEEMWGQEK 473
Query: 61 DRER-EKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERV 119
R EK ++E + + E+ RD++++ + ++ E D ER ++ +++M +
Sbjct: 474 KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMRE-QKKMWQQ 532
Query: 120 RDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179
++ RE++K +E++T + ++ RE + RERE + R+ E+ RE+E + + + E+ R
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERMREREK-KMREEEEMMREQEEKMQEQEEKMR 591
Query: 180 ETKERERHTDMERERQRETDRKRDRQRESERERD 213
E +E+ + + + Q E +++ + + E D
Sbjct: 592 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED 625
Score = 70.9 bits (172), Expect = 8e-13
Identities = 56/212 (26%), Positives = 114/212 (53%), Gaps = 25/212 (11%)
Query: 13 ETETMDRQRER---RRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTD 69
+ E M +Q E + E + ++ R E K + E+ ++++ + + ++ R++E+
Sbjct: 411 QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWG 470
Query: 70 REGERQRE---RERDRDRQRETERERDKER----ETDRHTETDRERQKQKEREMERVRDR 122
+E + R+ RE++ + E+ RD+E+ + +R E D ER ++KE ER+R++
Sbjct: 471 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQD-ERLREKE---ERMREQ 526
Query: 123 ERE-KQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRET 181
++ +Q+E RE + +E +++ Q E+ RE E+R RERE++ + E E RE
Sbjct: 527 KKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE-------EERMREREKKMREEEEMMREQ 579
Query: 182 KERERHTDMERERQRETDRKRDRQRESERERD 213
+E+ + + E+ RE + K Q E +E++
Sbjct: 580 EEKMQE---QEEKMREQEEKMWEQEEKMQEQE 608
Score = 70.5 bits (171), Expect = 1e-12
Identities = 50/201 (24%), Positives = 94/201 (46%), Gaps = 11/201 (5%)
Query: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
E KT + E R+RE++ + E R +E K +++ + Q ++ +E
Sbjct: 546 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQ 605
Query: 62 REREKQTDREGERQRERERDRDRQRET----ERERDKERETDRHTETDRER-QKQKEREM 116
+ EK ++E + + E D+ +++E + E+ +E+E + ++ R Q++K RE
Sbjct: 606 EQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 665
Query: 117 ERVRDREREKQKEMGRERQTDRETDRERERQ--AERERETGRERKT----EDRHRERERE 170
E + EK +E + Q E RE+E + + E+ G+E K E + E
Sbjct: 666 EEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMR 725
Query: 171 RKRERERKRETKERERHTDME 191
K ER R ++ K +ER + E
Sbjct: 726 EKEERIRDQKEKMQERLPEHE 746
Score = 66.2 bits (160), Expect = 2e-11
Identities = 50/208 (24%), Positives = 112/208 (53%), Gaps = 11/208 (5%)
Query: 11 HTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNR---ERDRDREREKQ 67
+ T T + +++ E + A+ K+E + + ++ +R ER + + + +++
Sbjct: 176 YRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEE 235
Query: 68 TDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRE---R 124
R+ E RE+E+ + R++E + R +ER ++ + RE++++ R+ +R+R++E R
Sbjct: 236 MWRQEEELREQEK-KIRKQEEKMWRQEERLREQEGKM-REQEEKMRRQEKRLREQEKELR 293
Query: 125 EKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKER 184
E++KE+ RE++ RE + + + Q E+ E + + ++ R+ ER E+E++ +E+
Sbjct: 294 EQEKEL-REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 352
Query: 185 ERHTDMER--ERQRETDRKRDRQRESER 210
+ ER E+ K +R RE E+
Sbjct: 353 KMRDQEERMWEQDERLREKEERMREQEK 380
Score = 65.5 bits (158), Expect = 3e-11
Identities = 43/174 (24%), Positives = 88/174 (50%), Gaps = 6/174 (3%)
Query: 13 ETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREG 72
+ E M Q E+ RE + + +E E +++ E D+ +E+E+ +
Sbjct: 579 QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE 638
Query: 73 ERQRERERDRDRQRETERERD-KERETDRHTETDRERQKQKEREMERVRDREREKQKEM- 130
E+ +E+E Q E RE++ K RE + + E+ +++E +M+ ++ RE++++M
Sbjct: 639 EKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMR 698
Query: 131 GRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKER 184
G+E ++ +E + + E+ G+E E R R+++ K + ER E +ER
Sbjct: 699 GQE---EKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQ-ERLPEHEER 748
Score = 57.8 bits (138), Expect = 7e-09
Identities = 42/194 (21%), Positives = 97/194 (50%), Gaps = 6/194 (3%)
Query: 26 ETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQ 85
E +ERD + + + ++ +E+ R E EK + ++ +R+ +R +
Sbjct: 163 ELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKF 222
Query: 86 RETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEM-GRERQTDRETDRER 144
+ + + +E E + Q++K R+ E R+ E+ +E G+ R+ + + R+
Sbjct: 223 LLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQE 282
Query: 145 ERQAERE---RETGRERKTEDRHRERERERKRERER--KRETKERERHTDMERERQRETD 199
+R E+E RE +E + + + RE+E + + + E+ ++E K RE+ M R+ +R +
Sbjct: 283 KRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWE 342
Query: 200 RKRDRQRESERERD 213
+++ + + ++ RD
Sbjct: 343 QEKQMREQEQKMRD 356
Score = 55.1 bits (131), Expect = 4e-08
Identities = 42/180 (23%), Positives = 91/180 (50%), Gaps = 13/180 (7%)
Query: 43 HSERDRQRDRERNRERDR-DREREKQTDREGERQRERERDRDRQRETERERDKERETDRH 101
H + DR + E +ERD E + T E +++ +++ R E E+ + + +
Sbjct: 154 HKKADRYIE-ELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKE 212
Query: 102 TETDRERQK---------QKEREMERVRDREREKQKEMGR-ERQTDRETDRERERQAERE 151
+ ER K + EM R + RE++K++ + E + R+ +R RE++ +
Sbjct: 213 LKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMR 272
Query: 152 RETGRERKTEDRHRERERE-RKRERERKRETKERERHTDMERERQRETDRKRDRQRESER 210
+ + R+ E R RE+E+E R++E+E + + K RE+ M+ + ++ +++ + + E+
Sbjct: 273 EQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 92.0 bits (227), Expect = 3e-19
Identities = 58/192 (30%), Positives = 95/192 (49%), Gaps = 9/192 (4%)
Query: 3 SKTEGRHTHTETE-TMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRER--- 58
SK H + E + D+ RER ++ DR K ++R S R R R R+RER
Sbjct: 21 SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKR---KERKSSRGRSHSRSRSRERRHR 77
Query: 59 DRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMER 118
R RER+K R ER++ R R R+R++ R R+++R R R R + + R R
Sbjct: 78 SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRI-RSRSRSRSRHRHRTRSRSR 136
Query: 119 VRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERK 178
R R R+++K + + R+ R R R R T + + E R ER +K + +R+
Sbjct: 137 TRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQ-EALARRLERAKKLQEQRE 195
Query: 179 RETKERERHTDM 190
+E E+++ ++
Sbjct: 196 KEMVEKQKQQEI 207
Score = 85.1 bits (209), Expect = 4e-17
Identities = 56/196 (28%), Positives = 88/196 (44%), Gaps = 14/196 (7%)
Query: 21 RERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERER 80
++ RR +++ K E E + RER + +R K+ +R+ R R R
Sbjct: 9 KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
Query: 81 DRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRET 140
R R+R R R +ER+ R +R++ + + RE ++ R R RE+++ R R R
Sbjct: 69 SRSRERR-HRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR---RIRSRSRSR 124
Query: 141 DRERERQAERERETGRERKTEDRHRERERERKRERERKRETKE---RERHTDMERE---- 193
R R R R R R R DR + E+ R+ R R R R+T M+ +
Sbjct: 125 SRHRHRTRSRSRTRSRSR---DRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALA 181
Query: 194 RQRETDRKRDRQRESE 209
R+ E +K QRE E
Sbjct: 182 RRLERAKKLQEQREKE 197
Score = 81.3 bits (199), Expect = 6e-16
Identities = 45/149 (30%), Positives = 75/149 (50%), Gaps = 11/149 (7%)
Query: 70 REGERQRERERDRDRQRETERERDKERETDR------HTETDRERQKQKEREMERVRDRE 123
++G R +++ ++ ++E DKE +D+ +E +R K+KER+ R R
Sbjct: 9 KQGRRHESKDKS-SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 67
Query: 124 REKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKE 183
R + +E R R RE + R R ER++ R R +R + R R R+R+R + ++
Sbjct: 68 RSRSRER-RHRSRSRERKKSRSRSRERKKSRSRSR---ERKKSRSRSRERKRRIRSRSRS 123
Query: 184 RERHTDMERERQRETDRKRDRQRESERER 212
R RH R R R R RDR++ E+ R
Sbjct: 124 RSRHRHRTRSRSRTRSRSRDRKKRIEKPR 152
Score = 60.1 bits (144), Expect = 1e-09
Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 14/114 (12%)
Query: 100 RHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERK 159
RH D+ +K K E ++E + GRER E +R ++ ER+ GR
Sbjct: 13 RHESKDKSSKKHKSEE-----HNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 67
Query: 160 TEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
R R RER + ++ER++ RER++ R R+R++ R R+
Sbjct: 68 ---------RSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRE 112
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.123 0.320
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,959,679
Number of Sequences: 37866
Number of extensions: 457181
Number of successful extensions: 65270
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1470
Number of HSP's successfully gapped in prelim test: 790
Number of HSP's that attempted gapping in prelim test: 5401
Number of HSP's gapped (non-prelim): 19981
length of query: 213
length of database: 18,247,518
effective HSP length: 98
effective length of query: 115
effective length of database: 14,536,650
effective search space: 1671714750
effective search space used: 1671714750
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.