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Search of human proteins with 117320518
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117320518 complement factor H-related 4 [Homo sapiens]
(331 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117320518 complement factor H-related 4 [Homo sapiens] 716 0.0
gi|54792787 complement factor H-related 3 [Homo sapiens] 475 e-134
gi|118442839 complement factor H-related 1 [Homo sapiens] 268 5e-72
gi|239758113 PREDICTED: similar to complement factor H-related 1... 268 5e-72
gi|62739186 complement factor H isoform a precursor [Homo sapiens] 262 4e-70
gi|5031695 H factor (complement)-like 3 [Homo sapiens] 220 1e-57
gi|239758115 PREDICTED: similar to complement factor H-related 1... 205 4e-53
gi|13540563 complement factor H-related 5 [Homo sapiens] 200 2e-51
gi|62739188 complement factor H isoform b precursor [Homo sapiens] 160 1e-39
gi|110611237 coagulation factor XIII B subunit precursor [Homo s... 156 3e-38
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 80 2e-15
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 80 2e-15
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 80 2e-15
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 78 1e-14
gi|148886654 polydom [Homo sapiens] 75 1e-13
gi|54792123 complement component (3d/Epstein Barr virus) recepto... 70 3e-12
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi... 68 1e-11
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi... 68 1e-11
gi|42544177 complement component (3d/Epstein Barr virus) recepto... 68 1e-11
gi|148922949 complement component (3b/4b) receptor 1-like [Homo ... 66 5e-11
gi|81295416 sushi domain containing 4 isoform b [Homo sapiens] 64 2e-10
gi|168693643 decay accelerating factor for complement isoform 2 ... 62 9e-10
gi|10835143 decay accelerating factor for complement isoform 1 p... 62 9e-10
gi|4502503 complement component 4 binding protein, alpha chain p... 60 3e-09
gi|153266841 apolipoprotein H precursor [Homo sapiens] 57 2e-08
gi|32261332 seizure related 6 homolog (mouse)-like precursor [Ho... 54 1e-07
gi|116174738 pappalysin 2 isoform 1 [Homo sapiens] 50 2e-06
gi|5454086 sushi-repeat-containing protein, X-linked [Homo sapiens] 50 2e-06
gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 ... 49 5e-06
gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [H... 49 5e-06
>gi|117320518 complement factor H-related 4 [Homo sapiens]
Length = 331
Score = 716 bits (1847), Expect = 0.0
Identities = 331/331 (100%), Positives = 331/331 (100%)
Query: 1 MLLLINVILTLWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNF 60
MLLLINVILTLWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNF
Sbjct: 1 MLLLINVILTLWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNF 60
Query: 61 VTPSGSYWDYIHCTQDGWSPTVPCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPG 120
VTPSGSYWDYIHCTQDGWSPTVPCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPG
Sbjct: 61 VTPSGSYWDYIHCTQDGWSPTVPCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPG 120
Query: 121 YATADGNSSGSITCLQNGWSAQPICIKFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGY 180
YATADGNSSGSITCLQNGWSAQPICIKFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGY
Sbjct: 121 YATADGNSSGSITCLQNGWSAQPICIKFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGY 180
Query: 181 EISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQC 240
EISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQC
Sbjct: 181 EISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQC 240
Query: 241 QSYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIE 300
QSYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIE
Sbjct: 241 QSYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIE 300
Query: 301 FMCKLGYNANTSVLSFQAVCREGIVEYPRCE 331
FMCKLGYNANTSVLSFQAVCREGIVEYPRCE
Sbjct: 301 FMCKLGYNANTSVLSFQAVCREGIVEYPRCE 331
>gi|54792787 complement factor H-related 3 [Homo sapiens]
Length = 330
Score = 475 bits (1223), Expect = e-134
Identities = 224/336 (66%), Positives = 260/336 (77%), Gaps = 11/336 (3%)
Query: 1 MLLLINVILTLWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNF 60
MLLLINVILTLWVSCANGQ VKPCDFP+I+HGGL+++++RR YFP A G+ YSYYCD++F
Sbjct: 1 MLLLINVILTLWVSCANGQ-VKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHF 59
Query: 61 VTPSGSYWDYIHCTQDGWSPTVPCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPG 120
TPSGSYWDYIHCTQ+GWSP VPCLR C +ENG+ ++ + C PG
Sbjct: 60 ETPSGSYWDYIHCTQNGWSPAVPCLRKCYFP--YLENGYNQNYGRKFVQGNSTEVACHPG 117
Query: 121 YATADGNSSGSITCLQNGWSAQPICIKF-----CDMPVFENSRAKSNGMRFKLHDTLDYE 175
Y ++ +TC + GWS P CI+ D+ + EN + + L+ + Y+
Sbjct: 118 YGLPKAQTT--VTCTEKGWSPTPRCIRVRTCSKSDIEI-ENGFISESSSIYILNKEIQYK 174
Query: 176 CYDGYEISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSR 235
C GY + GN++GSI C ++GWS P C NSSEKCGPPPPISNGDTTSFLLKVYVPQSR
Sbjct: 175 CKPGYATADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSR 234
Query: 236 VEYQCQSYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIQLKGKSDIKYYAKT 295
VEYQCQ YYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNI+LKG+SD KYYAKT
Sbjct: 235 VEYQCQPYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKT 294
Query: 296 GDTIEFMCKLGYNANTSVLSFQAVCREGIVEYPRCE 331
GDTIEFMCKLGYNANTS+LSFQAVCREGIVEYPRCE
Sbjct: 295 GDTIEFMCKLGYNANTSILSFQAVCREGIVEYPRCE 330
>gi|118442839 complement factor H-related 1 [Homo sapiens]
Length = 330
Score = 268 bits (685), Expect = 5e-72
Identities = 134/335 (40%), Positives = 194/335 (57%), Gaps = 13/335 (3%)
Query: 1 MLLLINVILTLWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNF 60
M LL++VIL +S G E CDFP+I HG LY + + + G+ + Y C+ NF
Sbjct: 1 MWLLVSVILISRISSVGG-EATFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNF 59
Query: 61 VTPSGSYWDYIHCTQDGWSPTVPCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPG 120
V+PS S+W I CT++GWSPT CLR C +E NG S ++ +Q C G
Sbjct: 60 VSPSKSFWTRITCTEEGWSPTPKCLRLCFFPFVE--NGHSESSGQTHLEGDTVQIICNTG 117
Query: 121 YATADGNSSGSITCLQNGWSAQPIC----IKFCDMPVFENSRAKSNGM-RFKLHDTLDYE 175
Y N+ +I+C++ GWS P C + P +N+ S M ++ + + YE
Sbjct: 118 YRLQ--NNENNISCVERGWSTPPKCRSTDTSCVNPPTVQNAHILSRQMSKYPSGERVRYE 175
Query: 176 CYDGYEISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSR 235
C YE+ +G+ ++C W+ P C +S+ KCGPPPPI NGD TSF L VY P S
Sbjct: 176 CRSPYEM-FGDE--EVMCLNGNWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASS 232
Query: 236 VEYQCQSYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIQLKGKSDIKYYAKT 295
VEYQCQ+ Y+L+G+ +TC NG+WSEPP+C+HPC+I+ E M NI L+ + K Y +T
Sbjct: 233 VEYQCQNLYQLEGNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLYLRT 292
Query: 296 GDTIEFMCKLGYNANTSVLSFQAVCREGIVEYPRC 330
G++ EF+CK GY ++ + + C +G +EYP C
Sbjct: 293 GESAEFVCKRGYRLSSRSHTLRTTCWDGKLEYPTC 327
>gi|239758113 PREDICTED: similar to complement factor H-related 1
isoform 1 [Homo sapiens]
Length = 330
Score = 268 bits (685), Expect = 5e-72
Identities = 134/335 (40%), Positives = 194/335 (57%), Gaps = 13/335 (3%)
Query: 1 MLLLINVILTLWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNF 60
M LL++VIL +S G E CDFP+I HG LY + + + G+ + Y C+ NF
Sbjct: 1 MWLLVSVILISRISSVGG-EATFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNF 59
Query: 61 VTPSGSYWDYIHCTQDGWSPTVPCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPG 120
V+PS S+W I CT++GWSPT CLR C +E NG S ++ +Q C G
Sbjct: 60 VSPSKSFWTRITCTEEGWSPTPKCLRLCFFPFVE--NGHSESSGQTHLEGDTVQIICNTG 117
Query: 121 YATADGNSSGSITCLQNGWSAQPIC----IKFCDMPVFENSRAKSNGM-RFKLHDTLDYE 175
Y N+ +I+C++ GWS P C + P +N+ S M ++ + + YE
Sbjct: 118 YRLQ--NNENNISCVERGWSTPPKCRSTDTSCVNPPTVQNAHILSRQMSKYPSGERVRYE 175
Query: 176 CYDGYEISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSR 235
C YE+ +G+ ++C W+ P C +S+ KCGPPPPI NGD TSF L VY P S
Sbjct: 176 CRSPYEM-FGDE--EVMCLNGNWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASS 232
Query: 236 VEYQCQSYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIQLKGKSDIKYYAKT 295
VEYQCQ+ Y+L+G+ +TC NG+WSEPP+C+HPC+I+ E M NI L+ + K Y +T
Sbjct: 233 VEYQCQNLYQLEGNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLYLRT 292
Query: 296 GDTIEFMCKLGYNANTSVLSFQAVCREGIVEYPRC 330
G++ EF+CK GY ++ + + C +G +EYP C
Sbjct: 293 GESAEFVCKRGYRLSSRSHTLRTTCWDGKLEYPTC 327
>gi|62739186 complement factor H isoform a precursor [Homo sapiens]
Length = 1231
Score = 262 bits (669), Expect = 4e-70
Identities = 144/346 (41%), Positives = 193/346 (55%), Gaps = 71/346 (20%)
Query: 21 VKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWSP 80
+KPCD+P+I+HGGLY++++RR YFP A G+ YSYYCD++F TPSGSYWD+IHCTQDGWSP
Sbjct: 322 LKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWSP 381
Query: 81 ----------------------------------------------TVPCL--------- 85
TV C+
Sbjct: 382 AVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCMENGWSPTPR 441
Query: 86 ----RTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSA 141
+TCSKS I+IENGFISES Y L ++ +Y+CK GY TADG +SGSITC ++GWSA
Sbjct: 442 CIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGETSGSITCGKDGWSA 501
Query: 142 QPICIKFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDGWSHF 201
QP CIK CD+PVF N+R K++ FKL+DTLDYEC+DGYE + G+TTGSIVCG +GWS
Sbjct: 502 QPTCIKSCDIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNGWSDL 561
Query: 202 PTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSN-GEWS 260
P CY E+ P I Y +++ C+ + + G N V C + G
Sbjct: 562 PICY---ERECELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGLSP 618
Query: 261 EPPRC---IHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMC 303
+ P C + C E +N N++ K K + + + +E+ C
Sbjct: 619 DLPICKEQVQSCGPPPELLN-GNVKEKTKEEYGH----SEVVEYYC 659
Score = 207 bits (528), Expect = 8e-54
Identities = 111/313 (35%), Positives = 171/313 (54%), Gaps = 19/313 (6%)
Query: 23 PCDFP-EIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWSPT 81
PC P EI HG + + S Y G+ +Y C + F + C + WS
Sbjct: 930 PCKSPPEISHGVVAHMSDSYQY-----GEEVTYKCFEGFGIDGPAI---AKCLGEKWSHP 981
Query: 82 VPCLRTCSKSDIEIENGF-ISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWS 140
C++T S EN + E +Y +++ Y C Y DG S+ +TC+ + W+
Sbjct: 982 PSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCAT-YYKMDGASN--VTCINSRWT 1038
Query: 141 AQPIC--IKFCDMPVFENSRAKSNGM-RFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG 197
+P C + P +N+ S M ++ + + Y+C YE+ +G+ ++C
Sbjct: 1039 GRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEM-FGDE--EVMCLNGN 1095
Query: 198 WSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNG 257
W+ P C +S+ KCGPPPPI NGD TSF L VY P S VEYQCQ+ Y+L+G+ +TC NG
Sbjct: 1096 WTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNG 1155
Query: 258 EWSEPPRCIHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSFQ 317
+WSEPP+C+HPC+I+ E M NI L+ + K Y++TG+++EF+CK GY ++ + +
Sbjct: 1156 QWSEPPKCLHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVCKRGYRLSSRSHTLR 1215
Query: 318 AVCREGIVEYPRC 330
C +G +EYP C
Sbjct: 1216 TTCWDGKLEYPTC 1228
Score = 124 bits (311), Expect = 1e-28
Identities = 86/293 (29%), Positives = 133/293 (45%), Gaps = 25/293 (8%)
Query: 47 AAGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWSPTVPCLRTCSKSDIEI-ENGFISESSS 105
A + Y C +VT G I C +DGWS C+++C DI + N +
Sbjct: 468 ALKEKAKYQCKLGYVTADGETSGSITCGKDGWSAQPTCIKSC---DIPVFMNARTKNDFT 524
Query: 106 IYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICI-KFCDMPVFENSRAKSNGM 164
+ LN + Y+C GY + G+++GSI C NGWS PIC + C++P +
Sbjct: 525 WFKLNDTLDYECHDGYESNTGSTTGSIVCGYNGWSDLPICYERECELPKIDVHLVPDRKK 584
Query: 165 -RFKLHDTLDYECYDGYEISYGNTTGSIVCGEDGWS-HFPTCYNSSEKCGPPPPISNGDT 222
++K+ + L + C G+ I N S+ C G S P C + CGPPP + NG+
Sbjct: 585 DQYKVGEVLKFSCKPGFTIVGPN---SVQCYHFGLSPDLPICKEQVQSCGPPPELLNGNV 641
Query: 223 TSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIQ 282
+ Y VEY C + ++G N + C +GEW+ P C I EE+ + +
Sbjct: 642 KEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCVDGEWTTLPVC-----IVEESTCGDIPE 696
Query: 283 LK----GKSDIKYYAKTGDTIEFMCKLGYNANTSVLSFQAVCREGI-VEYPRC 330
L+ S YY GD++EF C + T + C G+ + P+C
Sbjct: 697 LEHGWAQLSSPPYY--YGDSVEFNCSESF---TMIGHRSITCIHGVWTQLPQC 744
Score = 112 bits (281), Expect = 3e-25
Identities = 82/258 (31%), Positives = 113/258 (43%), Gaps = 17/258 (6%)
Query: 12 WVSCANGQEVKPCDFP-EIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDY 70
W S E PC P +I+HG + S R A G SY C+ F S +
Sbjct: 858 WQSIPLCVEKIPCSQPPQIEHGTI--NSSRSSQESYAHGTKLSYTCEGGFRI---SEENE 912
Query: 71 IHCTQDGWSPTVPCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSG 130
C WS C KS EI +G ++ S Y +E+ YKC G+ DG +
Sbjct: 913 TTCYMGKWSSPPQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFG-IDGPAIA 971
Query: 131 SITCLQNGWSAQPICIK--FCDMPVFENSRAKSNGMR-FKLHDTLDYECYDGYEISYGNT 187
CL WS P CIK +P FEN+ +K + + Y C Y++ +
Sbjct: 972 K--CLGEKWSHPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKM---DG 1026
Query: 188 TGSIVCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQ 247
++ C W+ PTC ++S C PP + N S + Y RV YQC+S YE+
Sbjct: 1027 ASNVTCINSRWTGRPTCRDTS--CVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMF 1084
Query: 248 GSNYVTCSNGEWSEPPRC 265
G V C NG W+EPP+C
Sbjct: 1085 GDEEVMCLNGNWTEPPQC 1102
Score = 89.0 bits (219), Expect = 5e-18
Identities = 78/297 (26%), Positives = 120/297 (40%), Gaps = 40/297 (13%)
Query: 49 GQSYSYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVP-CLRTCSKSDIEIENGFISESSSI 106
GQ+ + C+ + + +HC+ DG WS P C+ KS ++ NG I
Sbjct: 171 GQAVRFVCNSGYKIEGD---EEMHCSDDGFWSKEKPKCVEISCKSP-DVINGSPISQKII 226
Query: 107 YILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPIC-IKFCDMPVFENSRAKSNGMR 165
Y N+ QYKC GY + + G C ++GW P C K CD P N ++
Sbjct: 227 YKENERFQYKCNMGY---EYSERGDAVCTESGWRPLPSCEEKSCDNPYIPNGDYSPLRIK 283
Query: 166 FKLHDTLDYECYDG-YEISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTS 224
+ D + Y+C +G Y + GNT C GW P C + + C P G
Sbjct: 284 HRTGDEITYQCRNGFYPATRGNTA---KCTSTGWIPAPRC--TLKPCDYPDIKHGGLYHE 338
Query: 225 FLLKVYVPQS---RVEYQCQSYYELQGSNY---VTCSNGEWSEPPRCIHPCII--TEENM 276
+ + Y P + Y C ++E +Y + C+ WS C+ C E
Sbjct: 339 NMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWSPAVPCLRKCYFPYLENGY 398
Query: 277 NKNNIQLKGKSDIKYYAKTGDTIEFMCKLGY---NANTSVLSFQAVCREGIVEYPRC 330
N+N+ G+ ++ G +I+ C GY A T+V + G PRC
Sbjct: 399 NQNH----GRKFVQ-----GKSIDVACHPGYALPKAQTTVTCME----NGWSPTPRC 442
Score = 75.5 bits (184), Expect = 6e-14
Identities = 65/288 (22%), Positives = 112/288 (38%), Gaps = 31/288 (10%)
Query: 21 VKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWSP 80
+K CD P + + + + Y C + + +GS I C +GWS
Sbjct: 506 IKSCDIPVFMNA-----RTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNGWSD 560
Query: 81 TVPCL-RTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGW 139
C R C I++ Y + + +++ CKPG+ NS + C G
Sbjct: 561 LPICYERECELPKIDVHL-VPDRKKDQYKVGEVLKFSCKPGFTIVGPNS---VQCYHFGL 616
Query: 140 SAQ-PIC---IKFCDMP--VFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVC 193
S PIC ++ C P + + + + + ++Y C + + N I C
Sbjct: 617 SPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPN---KIQC 673
Query: 194 GEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVT 253
+ W+ P C CG P + +G Y S VE+ C + + G +T
Sbjct: 674 VDGEWTTLPVCIVEESTCGDIPELEHGWAQLSSPPYYYGDS-VEFNCSESFTMIGHRSIT 732
Query: 254 CSNGEWSEPPRCI----------HPCIITEENMNKNNIQLKGKSDIKY 291
C +G W++ P+C+ II EE++ KN + S+I+Y
Sbjct: 733 CIHGVWTQLPQCVAIDKLKKCKSSNLIILEEHL-KNKKEFDHNSNIRY 779
Score = 74.3 bits (181), Expect = 1e-13
Identities = 60/255 (23%), Positives = 95/255 (37%), Gaps = 35/255 (13%)
Query: 25 DFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWSPTVPC 84
D PE++HG S Y G S + C ++F I C W+ C
Sbjct: 693 DIPELEHGWAQLSSPPYYY-----GDSVEFNCSESFTMIGHRS---ITCIHGVWTQLPQC 744
Query: 85 -----LRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSI--TCLQN 137
L+ C S++ I + + N I+Y+C+ G I C+
Sbjct: 745 VAIDKLKKCKSSNLIILEEHLKNKKE-FDHNSNIRYRCR--------GKEGWIHTVCING 795
Query: 138 GWSAQPIC----IKFCDMPV-FENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIV 192
W + C I+ C P NS + + ++ + + C + Y I G I
Sbjct: 796 RWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGE---EIT 852
Query: 193 CGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLL--KVYVPQSRVEYQCQSYYELQGSN 250
C + W P C C PP I +G S + Y +++ Y C+ + + N
Sbjct: 853 CKDGRWQSIPLCVEKIP-CSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEEN 911
Query: 251 YVTCSNGEWSEPPRC 265
TC G+WS PP+C
Sbjct: 912 ETTCYMGKWSSPPQC 926
Score = 73.6 bits (179), Expect = 2e-13
Identities = 68/303 (22%), Positives = 113/303 (37%), Gaps = 53/303 (17%)
Query: 27 PEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWSPTVPCL- 85
PE+ +G + K+ + YYC+ F+ + I C W+ C+
Sbjct: 634 PELLNGNVKEKTKEEY----GHSEVVEYYCNPRFLMKGPNK---IQCVDGEWTTLPVCIV 686
Query: 86 --RTCSKSDI-EIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQ 142
TC DI E+E+G+ SS Y +++ C + T G+ S ITC+ W+
Sbjct: 687 EESTCG--DIPELEHGWAQLSSPPYYYGDSVEFNCSESF-TMIGHRS--ITCIHGVWTQL 741
Query: 143 PICIKFCDMPVFENSRA------KSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGED 196
P C+ + ++S N F + + Y C G++
Sbjct: 742 PQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCR----------------GKE 785
Query: 197 GWSHFPTCYNSS------------EKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYY 244
GW H C N + C PPP I N + L Y +V CQ Y
Sbjct: 786 GWIH-TVCINGRWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTLN-YRDGEKVSVLCQENY 843
Query: 245 ELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCK 304
+Q +TC +G W P C+ ++ ++ +S + YA G + + C+
Sbjct: 844 LIQEGEEITCKDGRWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAH-GTKLSYTCE 902
Query: 305 LGY 307
G+
Sbjct: 903 GGF 905
Score = 57.0 bits (136), Expect = 2e-08
Identities = 74/267 (27%), Positives = 108/267 (40%), Gaps = 43/267 (16%)
Query: 84 CLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSA-Q 142
C + + EI G S S Y + YKC+PGY + GN + C + W A
Sbjct: 21 CNELPPRRNTEILTG--SWSDQTYPEGTQAIYKCRPGYRSL-GNV--IMVCRKGEWVALN 75
Query: 143 PI-------CIKFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGY----EISYGNTTGSI 191
P+ C D P + + G F+ Y C +GY EI+Y
Sbjct: 76 PLRKCQKRPCGHPGDTPF--GTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRE----- 128
Query: 192 VCGEDGWSH-FPTCYNSSEKCGPPPPISNGDTTSFLL---KVYVPQSRVEYQCQSYYELQ 247
C DGW++ P C KC P NG S + + Y V + C S Y+++
Sbjct: 129 -CDTDGWTNDIPIC--EVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIE 185
Query: 248 GSNYVTCS-NGEWS-EPPRCIHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKL 305
G + CS +G WS E P+C+ + + +N + I K I Y K + ++ C +
Sbjct: 186 GDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQK----IIY--KENERFQYKCNM 239
Query: 306 GYNANTSVLSFQAVCRE-GIVEYPRCE 331
GY + AVC E G P CE
Sbjct: 240 GYEYSE---RGDAVCTESGWRPLPSCE 263
Score = 30.8 bits (68), Expect = 1.7
Identities = 16/54 (29%), Positives = 26/54 (48%), Gaps = 2/54 (3%)
Query: 208 SEKCGPPPPISNGD--TTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEW 259
+E C PP N + T S+ + Y ++ Y+C+ Y G+ + C GEW
Sbjct: 18 AEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGEW 71
>gi|5031695 H factor (complement)-like 3 [Homo sapiens]
Length = 270
Score = 220 bits (561), Expect = 1e-57
Identities = 103/219 (47%), Positives = 140/219 (63%), Gaps = 5/219 (2%)
Query: 115 YKCKPGYATADGNSSGSITCLQNGWSAQPICIKFCDMPVFENSRAKSNGMRFKLHDTLDY 174
Y C+ + + + ITC + GWS P C++ C P EN ++S+G DT+
Sbjct: 53 YSCEYNFVSPSKSFWTRITCAEEGWSPTPKCLRLCFFPFVENGHSESSGQTHLEGDTVQI 112
Query: 175 ECYDGYEISYGNTTGSIVCGEDGWSHFPTCYN--SSEKCGPPPPISNGDTTSFLLKVYVP 232
C GY + N +I C E GWS P C + S+EKCGPPPPI NGD TSFLL VY P
Sbjct: 113 ICNTGYRLQ--NNENNISCVERGWSTPPKCRSTISAEKCGPPPPIDNGDITSFLLSVYAP 170
Query: 233 QSRVEYQCQSYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIQLKGKSDIKYY 292
S VEYQCQ+ Y+L+G+N +TC NG+WSEPP+C+ PC+I++E M K NI+LK + K Y
Sbjct: 171 GSSVEYQCQNLYQLEGNNQITCRNGQWSEPPKCLDPCVISQEIMEKYNIKLKWTNQQKLY 230
Query: 293 AKTGDTIEFMCKLGYNANTSVLSFQAVCREGIVEYPRCE 331
++TGD +EF+CK GY+ T SF+A+C+ G + YP CE
Sbjct: 231 SRTGDIVEFVCKSGYHP-TKSHSFRAMCQNGKLVYPSCE 268
Score = 116 bits (290), Expect = 3e-26
Identities = 85/280 (30%), Positives = 127/280 (45%), Gaps = 33/280 (11%)
Query: 1 MLLLINVILTLWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNF 60
M LL++VIL +S G E CDFP+I HG LY + + + G+ + Y C+ NF
Sbjct: 1 MWLLVSVILISRISSVGG-EAMFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNF 59
Query: 61 VTPSGSYWDYIHCTQDGWSPTVPCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPG 120
V+PS S+W I C ++GWSPT CLR C +ENG S ++ +Q C G
Sbjct: 60 VSPSKSFWTRITCAEEGWSPTPKCLRLCFFP--FVENGHSESSGQTHLEGDTVQIICNTG 117
Query: 121 YATADGNSSGSITCLQNGWSAQPIC------IKFCDMPVFENSRAKSNGMR-FKLHDTLD 173
Y N+ +I+C++ GWS P C K P +N S + + +++
Sbjct: 118 YRLQ--NNENNISCVERGWSTPPKCRSTISAEKCGPPPPIDNGDITSFLLSVYAPGSSVE 175
Query: 174 YECYDGYEISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKV-YVP 232
Y+C + Y++ N I C WS P KC P IS + +K+ +
Sbjct: 176 YQCQNLYQLEGNN---QITCRNGQWSEPP-------KCLDPCVISQEIMEKYNIKLKWTN 225
Query: 233 QSR--------VEYQCQSYYELQGSN--YVTCSNGEWSEP 262
Q + VE+ C+S Y S+ C NG+ P
Sbjct: 226 QQKLYSRTGDIVEFVCKSGYHPTKSHSFRAMCQNGKLVYP 265
>gi|239758115 PREDICTED: similar to complement factor H-related 1
isoform 2 [Homo sapiens]
Length = 271
Score = 205 bits (522), Expect = 4e-53
Identities = 94/218 (43%), Positives = 131/218 (60%), Gaps = 4/218 (1%)
Query: 115 YKCKPGYATADGNSSGSITCLQNGWSAQPICIKFCDMPVFENSRAKSNGMRFKLHDTLDY 174
Y C+ + + + ITC + GWS P C++ C P EN ++S+G DT+
Sbjct: 53 YSCEYNFVSPSKSFWTRITCTEEGWSPTPKCLRLCFFPFVENGHSESSGQTHLEGDTVQI 112
Query: 175 ECYDGYEISYGNTTGSIVCGEDGWSHFPTCYN--SSEKCGPPPPISNGDTTSFLLKVYVP 232
C GY + N +I C E GWS P C + S+ KCGPPPPI NGD TSF L VY P
Sbjct: 113 ICNTGYRLQ--NNENNISCVERGWSTPPKCRSTDSTGKCGPPPPIDNGDITSFPLSVYAP 170
Query: 233 QSRVEYQCQSYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIQLKGKSDIKYY 292
S VEYQCQ+ Y+L+G+ +TC NG+WSEPP+C+HPC+I+ E M NI L+ + K Y
Sbjct: 171 ASSVEYQCQNLYQLEGNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLY 230
Query: 293 AKTGDTIEFMCKLGYNANTSVLSFQAVCREGIVEYPRC 330
+TG++ EF+CK GY ++ + + C +G +EYP C
Sbjct: 231 LRTGESAEFVCKRGYRLSSRSHTLRTTCWDGKLEYPTC 268
Score = 116 bits (290), Expect = 3e-26
Identities = 85/281 (30%), Positives = 129/281 (45%), Gaps = 34/281 (12%)
Query: 1 MLLLINVILTLWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNF 60
M LL++VIL +S G E CDFP+I HG LY + + + G+ + Y C+ NF
Sbjct: 1 MWLLVSVILISRISSVGG-EATFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNF 59
Query: 61 VTPSGSYWDYIHCTQDGWSPTVPCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPG 120
V+PS S+W I CT++GWSPT CLR C +ENG S ++ +Q C G
Sbjct: 60 VSPSKSFWTRITCTEEGWSPTPKCLRLCFFP--FVENGHSESSGQTHLEGDTVQIICNTG 117
Query: 121 YATADGNSSGSITCLQNGWSAQPICI------KFCDMPVFENSRAKSNGMR-FKLHDTLD 173
Y N+ +I+C++ GWS P C K P +N S + + +++
Sbjct: 118 YRLQ--NNENNISCVERGWSTPPKCRSTDSTGKCGPPPPIDNGDITSFPLSVYAPASSVE 175
Query: 174 YECYDGYEISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLL------ 227
Y+C + Y++ GN I C WS P KC P IS ++ +
Sbjct: 176 YQCQNLYQLE-GNK--RITCRNGQWSEPP-------KCLHPCVISREIMENYNIALRWTA 225
Query: 228 --KVYVPQSR-VEYQCQSYYELQGSNY---VTCSNGEWSEP 262
K+Y+ E+ C+ Y L ++ TC +G+ P
Sbjct: 226 KQKLYLRTGESAEFVCKRGYRLSSRSHTLRTTCWDGKLEYP 266
>gi|13540563 complement factor H-related 5 [Homo sapiens]
Length = 569
Score = 200 bits (508), Expect = 2e-51
Identities = 113/319 (35%), Positives = 166/319 (52%), Gaps = 19/319 (5%)
Query: 19 QEVKPCDF-PEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDYIHCTQDG 77
++VK C + PE+++G ++ P G S C + + I C
Sbjct: 264 EQVKTCGYIPELEYG-----YVQPSVPPYQHGVSVEVNCRNEYAMIGNNM---ITCINGI 315
Query: 78 WSPTVPCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQN 137
W+ C+ T +I ++ + + + KE + + Y +D C+
Sbjct: 316 WTELPMCVATHQLKRCKIAG--VNIKTLLKLSGKEFNHNSRIRYRCSDIFRYRHSVCING 373
Query: 138 GWSAQPICIK----FCDMPV-FENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIV 192
W+ + C + FC P N++ + + ++ + + C + Y + IV
Sbjct: 374 KWNPEVDCTEKREQFCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAK---EIV 430
Query: 193 CGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYV 252
C + W P C S+ CGPPP I+NGDTTSF L VY P S V Y+CQS+Y+LQGS V
Sbjct: 431 CKDGRWQSLPRCVESTAYCGPPPSINNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSVTV 490
Query: 253 TCSNGEWSEPPRCIHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNANTS 312
TC N +WSEPPRC+ PC+++EENMNKNNIQLK ++D K YAKTGD +EF CK + A S
Sbjct: 491 TCRNKQWSEPPRCLDPCVVSEENMNKNNIQLKWRNDGKLYAKTGDAVEFQCKFPHKAMIS 550
Query: 313 VLSFQAVCREGIVEYPRCE 331
F+A+C+EG EYP CE
Sbjct: 551 SPPFRAICQEGKFEYPICE 569
Score = 181 bits (459), Expect = 8e-46
Identities = 100/271 (36%), Positives = 142/271 (52%), Gaps = 13/271 (4%)
Query: 1 MLLLINVILTLWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNF 60
MLLL +VIL WVS G+ CDFP+I HG LY + + G+ + Y C+ NF
Sbjct: 1 MLLLFSVILISWVSTVGGEGTL-CDFPKIHHGFLYDEEDYNPFSQVPTGEVFYYSCEYNF 59
Query: 61 VTPSGSYWDYIHCTQDGWSPTVPCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPG 120
V+PS S+W I CT++GWSPT CLR CS ++NG S I++ +Q C G
Sbjct: 60 VSPSKSFWTRITCTEEGWSPTPKCLRMCSFP--FVKNGHSESSGLIHLEGDTVQIICNTG 117
Query: 121 YATADGNSSGSITCLQNGWSAQPICI---KFCDMPVFE-NSRAKSNGMRFKLHDTLDYEC 176
Y+ N+ +I+C++ GWS PIC C +P+ E N A+ +K+ D L + C
Sbjct: 118 YSLQ--NNEKNISCVERGWSTPPICSFTKGECHVPILEANVDAQPKKESYKVGDVLKFSC 175
Query: 177 YDGYEISYGNTTGSIVCGEDGWS-HFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSR 235
I G + S+ C + GWS +FPTC CGPPP +SNG+ + Y
Sbjct: 176 RKNL-IRVG--SDSVQCYQFGWSPNFPTCKGQVRSCGPPPQLSNGEVKEIRKEEYGHNEV 232
Query: 236 VEYQCQSYYELQGSNYVTCSNGEWSEPPRCI 266
VEY C + + G + C +GEW+ P C+
Sbjct: 233 VEYDCNPNFIINGPKKIQCVDGEWTTLPTCV 263
Score = 32.3 bits (72), Expect = 0.60
Identities = 18/87 (20%), Positives = 38/87 (43%), Gaps = 10/87 (11%)
Query: 238 YQCQSYYELQGSNY---VTCSNGEWSEPPRCIHPCIITEENMNKNNIQLKGKSDIKYYAK 294
Y C+ + ++ +TC+ WS P+C+ C + + + + G ++
Sbjct: 53 YSCEYNFVSPSKSFWTRITCTEEGWSPTPKCLRMC--SFPFVKNGHSESSGLIHLE---- 106
Query: 295 TGDTIEFMCKLGYNANTSVLSFQAVCR 321
GDT++ +C GY+ + + V R
Sbjct: 107 -GDTVQIICNTGYSLQNNEKNISCVER 132
>gi|62739188 complement factor H isoform b precursor [Homo sapiens]
Length = 449
Score = 160 bits (406), Expect = 1e-39
Identities = 68/127 (53%), Positives = 90/127 (70%), Gaps = 4/127 (3%)
Query: 21 VKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWSP 80
+KPCD+P+I+HGGLY++++RR YFP A G+ YSYYCD++F TPSGSYWD+IHCTQDGWSP
Sbjct: 322 LKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWSP 381
Query: 81 TVPCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWS 140
VPCLR C +ENG+ ++ K I C PGYA + ++TC++NGWS
Sbjct: 382 AVPCLRKCYFP--YLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQT--TVTCMENGWS 437
Query: 141 AQPICIK 147
P CI+
Sbjct: 438 PTPRCIR 444
Score = 89.0 bits (219), Expect = 5e-18
Identities = 78/297 (26%), Positives = 120/297 (40%), Gaps = 40/297 (13%)
Query: 49 GQSYSYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVP-CLRTCSKSDIEIENGFISESSSI 106
GQ+ + C+ + + +HC+ DG WS P C+ KS ++ NG I
Sbjct: 171 GQAVRFVCNSGYKIEGD---EEMHCSDDGFWSKEKPKCVEISCKSP-DVINGSPISQKII 226
Query: 107 YILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPIC-IKFCDMPVFENSRAKSNGMR 165
Y N+ QYKC GY + + G C ++GW P C K CD P N ++
Sbjct: 227 YKENERFQYKCNMGY---EYSERGDAVCTESGWRPLPSCEEKSCDNPYIPNGDYSPLRIK 283
Query: 166 FKLHDTLDYECYDG-YEISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTS 224
+ D + Y+C +G Y + GNT C GW P C + + C P G
Sbjct: 284 HRTGDEITYQCRNGFYPATRGNTA---KCTSTGWIPAPRC--TLKPCDYPDIKHGGLYHE 338
Query: 225 FLLKVYVPQS---RVEYQCQSYYELQGSNY---VTCSNGEWSEPPRCIHPCII--TEENM 276
+ + Y P + Y C ++E +Y + C+ WS C+ C E
Sbjct: 339 NMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWSPAVPCLRKCYFPYLENGY 398
Query: 277 NKNNIQLKGKSDIKYYAKTGDTIEFMCKLGY---NANTSVLSFQAVCREGIVEYPRC 330
N+N+ G+ ++ G +I+ C GY A T+V + G PRC
Sbjct: 399 NQNH----GRKFVQ-----GKSIDVACHPGYALPKAQTTVTCME----NGWSPTPRC 442
Score = 85.5 bits (210), Expect = 6e-17
Identities = 57/193 (29%), Positives = 81/193 (41%), Gaps = 13/193 (6%)
Query: 20 EVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWS 79
E K CD P I +G Y LR + G +Y C F + + CT GW
Sbjct: 263 EEKSCDNPYIPNGD--YSPLRIKH---RTGDEITYQCRNGFYPATRG--NTAKCTSTGWI 315
Query: 80 PTVPC-LRTCSKSDIEIENGFISESSSIYI---LNKEIQYKCKPGYATADGNSSGSITCL 135
P C L+ C DI+ + Y + K Y C + T G+ I C
Sbjct: 316 PAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCT 375
Query: 136 QNGWSAQPICIKFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGE 195
Q+GWS C++ C P EN +++G +F ++D C+ GY + TT + C E
Sbjct: 376 QDGWSPAVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTT--VTCME 433
Query: 196 DGWSHFPTCYNSS 208
+GWS P C S
Sbjct: 434 NGWSPTPRCIRVS 446
Score = 73.9 bits (180), Expect = 2e-13
Identities = 70/256 (27%), Positives = 97/256 (37%), Gaps = 35/256 (13%)
Query: 24 CDFPEIQHGG-----LYYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDYIHCTQDGW 78
C P++ +G + YK R + G YS D CT+ GW
Sbjct: 210 CKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAV-------------CTESGW 256
Query: 79 SPTVPCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPG-YATADGNSSGSITCLQN 137
P +P S + I NG S + EI Y+C+ G Y GN++ C
Sbjct: 257 RP-LPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTA---KCTST 312
Query: 138 GWSAQPIC-IKFCDMPVFENSRAKSNGMR-----FKLHDTLDYECYDGYEISYGNTTGSI 191
GW P C +K CD P ++ MR + Y C + +E G+ I
Sbjct: 313 GWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHI 372
Query: 192 VCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYEL-QGSN 250
C +DGWS C KC P + NG + K +V ++ C Y L +
Sbjct: 373 HCTQDGWSPAVPCLR---KCYFPY-LENGYNQNHGRK-FVQGKSIDVACHPGYALPKAQT 427
Query: 251 YVTCSNGEWSEPPRCI 266
VTC WS PRCI
Sbjct: 428 TVTCMENGWSPTPRCI 443
Score = 57.0 bits (136), Expect = 2e-08
Identities = 74/267 (27%), Positives = 108/267 (40%), Gaps = 43/267 (16%)
Query: 84 CLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSA-Q 142
C + + EI G S S Y + YKC+PGY + GN + C + W A
Sbjct: 21 CNELPPRRNTEILTG--SWSDQTYPEGTQAIYKCRPGYRSL-GNV--IMVCRKGEWVALN 75
Query: 143 PI-------CIKFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGY----EISYGNTTGSI 191
P+ C D P + + G F+ Y C +GY EI+Y
Sbjct: 76 PLRKCQKRPCGHPGDTPF--GTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRE----- 128
Query: 192 VCGEDGWSH-FPTCYNSSEKCGPPPPISNGDTTSFLL---KVYVPQSRVEYQCQSYYELQ 247
C DGW++ P C KC P NG S + + Y V + C S Y+++
Sbjct: 129 -CDTDGWTNDIPIC--EVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIE 185
Query: 248 GSNYVTCS-NGEWS-EPPRCIHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKL 305
G + CS +G WS E P+C+ + + +N + I K I Y K + ++ C +
Sbjct: 186 GDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQK----IIY--KENERFQYKCNM 239
Query: 306 GYNANTSVLSFQAVCRE-GIVEYPRCE 331
GY + AVC E G P CE
Sbjct: 240 GYEYSE---RGDAVCTESGWRPLPSCE 263
Score = 30.8 bits (68), Expect = 1.7
Identities = 16/54 (29%), Positives = 26/54 (48%), Gaps = 2/54 (3%)
Query: 208 SEKCGPPPPISNGD--TTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEW 259
+E C PP N + T S+ + Y ++ Y+C+ Y G+ + C GEW
Sbjct: 18 AEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGEW 71
>gi|110611237 coagulation factor XIII B subunit precursor [Homo
sapiens]
Length = 661
Score = 156 bits (394), Expect = 3e-38
Identities = 102/337 (30%), Positives = 155/337 (45%), Gaps = 26/337 (7%)
Query: 5 INVILTLWVSCANGQEVKPCDFPEIQHGGL--YYKSLRRLYFPAAAGQSYSYYCDQNFVT 62
+ I+ L +S E KPC FP +++G + YY + + YFP + + S++C + T
Sbjct: 6 LTFIIILIISGELYAEEKPCGFPHVENGRIAQYYYTFKSFYFPMSIDKKLSFFCLAGYTT 65
Query: 63 PSGSYWDYIHCTQDGWSPTVPCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYA 122
SG + CT +GWSP C + C+K D + NG+IS+ +Y + + ++Y C GY
Sbjct: 66 ESGRQEEQTTCTTEGWSPEPRCFKKCTKPD--LSNGYISDVKLLYKIQENMRYGCASGYK 123
Query: 123 TADGNSSGSITCLQNGWSAQPICIK---FCDMPVFENSRAKSNGMRFKLHDTLDYECYDG 179
T G + CL +GWS+QP C K C P N + FK+ D + YEC G
Sbjct: 124 TTGGKDEEVVQCLSDGWSSQPTCRKEHETCLAPELYNGNYSTTQKTFKVKDKVQYECATG 183
Query: 180 YEISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQ 239
Y + G T + C GWS P C + KC I NG + + Y V++
Sbjct: 184 YYTAGGKKTEEVECLTYGWSLTPKC--TKLKCSSLRLIENGYFHP-VKQTYEEGDVVQFF 240
Query: 240 CQSYYELQGSNYVTCSNGEW-SEPPRCIHPCIITEENMNK-NNIQLKGKSDIKYYAKT-- 295
C Y L GS+ + C N W E P C E N+ L S I+ ++ T
Sbjct: 241 CHENYYLSGSDLIQCYNFGWYPESPVC-------EGRRNRCPPPPLPINSKIQTHSTTYR 293
Query: 296 -GDTIEFMCKLGYNANTSVLSFQAVCREG-IVEYPRC 330
G+ + C+L + + S + C +G E P+C
Sbjct: 294 HGEIVHIECELNFEIHGSA---EIRCEDGKWTEPPKC 327
Score = 152 bits (384), Expect = 4e-37
Identities = 96/308 (31%), Positives = 140/308 (45%), Gaps = 27/308 (8%)
Query: 35 YYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWSPTVPCLR----TCSK 90
Y+ +++ Y G ++C +N+ SGS D I C GW P P C
Sbjct: 223 YFHPVKQTY---EEGDVVQFFCHENYYL-SGS--DLIQCYNFGWYPESPVCEGRRNRCPP 276
Query: 91 SDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICIK--- 147
+ I N I S+ Y + + +C+ + + S I C W+ P CI+
Sbjct: 277 PPLPI-NSKIQTHSTTYRHGEIVHIECELNFEI---HGSAEIRCEDGKWTEPPKCIEGQE 332
Query: 148 --FCDMPVF-ENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDGWSHFPTC 204
C+ P F EN A + + D + Y C GY + N I C W+ P C
Sbjct: 333 KVACEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSN---EITCNRGKWTLPPEC 389
Query: 205 YNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEWSEPPR 264
++E C PP + NG +L Y S VEY+C YY L+GS C G+WS PP
Sbjct: 390 VENNENCKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCEQGKWSSPPV 449
Query: 265 CIHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNAN--TSVLSFQAVCRE 322
C+ PC + + MN+NNI++K K + K GD I+F+CK GY+ + T + C
Sbjct: 450 CLEPCTVNVDYMNRNNIEMKWKYEGK--VLHGDLIDFVCKQGYDLSPLTPLSELSVQCNR 507
Query: 323 GIVEYPRC 330
G V+YP C
Sbjct: 508 GEVKYPLC 515
Score = 123 bits (309), Expect = 2e-28
Identities = 94/335 (28%), Positives = 147/335 (43%), Gaps = 34/335 (10%)
Query: 15 CANGQEVKPCDFPE-IQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDYIHC 73
C GQE C+ P I++G S ++Y+ G +Y C ++ + I C
Sbjct: 327 CIEGQEKVACEEPPFIENGAANLHS--KIYYN---GDKVTYACKSGYLLHGSNE---ITC 378
Query: 74 TQDGWSPTVPCLRT---CSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSG 130
+ W+ C+ C + + + Y ++Y+C Y S
Sbjct: 379 NRGKWTLPPECVENNENCKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKIS- 437
Query: 131 SITCLQNGWSAQPICIKFCDMPVFENSRAKSNGMRFK-----LH-DTLDYECYDGYEISY 184
C Q WS+ P+C++ C + V +R M++K LH D +D+ C GY++S
Sbjct: 438 --RCEQGKWSSPPVCLEPCTVNVDYMNRNNIE-MKWKYEGKVLHGDLIDFVCKQGYDLSP 494
Query: 185 GNTTG--SIVCGEDGWSHFPTCYNSSEK--CGPPPPISNGDTTSFLLKVYVPQSRVEYQC 240
S+ C G +P C K C PP I +G S + Y S VEY+C
Sbjct: 495 LTPLSELSVQCNR-GEVKYPLCTRKESKGMCTSPPLIKHGVIISSTVDTYENGSSVEYRC 553
Query: 241 QSYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIE 300
++ L+GS C +G W+ PP C+ PC ++ M KNN+ LK D + + G+ IE
Sbjct: 554 FDHHFLEGSREAYCLDGMWTTPPLCLEPCTLSFTEMEKNNLLLKWDFDNRPHILHGEYIE 613
Query: 301 FMCKLG-YNANT----SVLSFQAVCREGIVEYPRC 330
F+C+ Y A S+L Q C G ++YPRC
Sbjct: 614 FICRGDTYPAELYITGSILRMQ--CDRGQLKYPRC 646
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 80.5 bits (197), Expect = 2e-15
Identities = 74/264 (28%), Positives = 111/264 (42%), Gaps = 23/264 (8%)
Query: 51 SYSYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVPCLRTCSKSDIEIENGFISESSSIYIL 109
S Y C + ++ S CT +G WS T+P S D I + Y++
Sbjct: 3096 SVIYSCMEGYILSGPSVRQ---CTANGTWSGTLPNCTIISCGDPGIPANGLRYGDD-YVV 3151
Query: 110 NKEIQYKCKPGYATADGNSSGSITCLQNG-WS-AQPIC-IKFCDMPVFENSRAKSNGMRF 166
+ + Y C+PGY T + N S TC NG WS P C C P + S + G F
Sbjct: 3152 GQNVSYMCQPGY-TMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPP-QISNGRLEGTNF 3209
Query: 167 KLHDTLDYECYDGYEISYGNTTGSIVCGEDGWS-HFPTCYNSSEKCGPPPPISNGDTTSF 225
++ Y C GYE+S+ + G WS P C + CG P + G
Sbjct: 3210 DWGFSISYICSPGYELSFPAVLTCV--GNGTWSGEVPQCL--PKFCGDPGIPAQGKREG- 3264
Query: 226 LLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWS-EPPRCIHPCIITEENMNKNNIQL 283
K ++ QS V + C + L GS+ C ++G WS P CI P T+ + +
Sbjct: 3265 --KSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEP---TQTSCENPGVPR 3319
Query: 284 KGKSDIKYYAKTGDTIEFMCKLGY 307
G + + + G ++F CK G+
Sbjct: 3320 HGSQNNTFGFQVGSVVQFHCKKGH 3343
Score = 60.5 bits (145), Expect = 2e-09
Identities = 87/300 (29%), Positives = 124/300 (41%), Gaps = 46/300 (15%)
Query: 24 CDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTP-SGSYWDYIHCTQDG-WSPT 81
C P I GL Y GQ+ SY C + +GS CT +G WS
Sbjct: 3133 CGDPGIPANGLRYGD------DYVVGQNVSYMCQPGYTMELNGSR--IRTCTINGTWSGV 3184
Query: 82 VPCLR--TCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG- 138
+P R TC +I NG + ++ + I Y C PGY + +TC+ NG
Sbjct: 3185 MPTCRAVTCPTPP-QISNGRLEGTN--FDWGFSISYICSPGYELS---FPAVLTCVGNGT 3238
Query: 139 WSAQ-PICI-KFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGED 196
WS + P C+ KFC P ++ K G F + + C + I G++T +C D
Sbjct: 3239 WSGEVPQCLPKFCGDPGIP-AQGKREGKSFIYQSEVSFSCNFPF-ILVGSSTR--ICQAD 3294
Query: 197 G-WS-HFPTCYN----SSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSN 250
G WS P C S E G P S +T F + S V++ C+ + LQGS
Sbjct: 3295 GTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVG-----SVVQFHCKKGHLLQGST 3349
Query: 251 YVTC-SNGEWSE-PPRCI-HPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGY 307
TC + WS P CI H C E + N + + S G T+ + C+ G+
Sbjct: 3350 TRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSH-------GYTLIYTCQPGF 3402
Score = 45.1 bits (105), Expect = 9e-05
Identities = 53/191 (27%), Positives = 79/191 (41%), Gaps = 25/191 (13%)
Query: 83 PCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQ 142
P + SK + +IE+G + + ++ Y C PGY S + C NG +
Sbjct: 2896 PGIPANSKRESKIEHGNFTYGTVVF-------YDCNPGYFLF---GSSVLICQPNGQWDK 2945
Query: 143 PI--CIKF-CDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-W 198
P+ CI C P + S G ++ T+ Y C G G + S C +G W
Sbjct: 2946 PLPECIMIDCGHPGVPPNAVLS-GEKYTFGSTVHYSC-TGKRSLLGQS--SRTCQLNGHW 3001
Query: 199 SHF-PTCY-NSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-S 255
S P C +++ CG P +G + +S V Y C + Y L GS TC +
Sbjct: 3002 SGSQPHCSGDATGTCGDPGTPGHGSRQESNFRT---KSTVRYACDTGYILHGSEERTCLA 3058
Query: 256 NGEWS-EPPRC 265
NG W+ P C
Sbjct: 3059 NGSWTGRQPEC 3069
Score = 42.4 bits (98), Expect = 6e-04
Identities = 57/221 (25%), Positives = 85/221 (38%), Gaps = 41/221 (18%)
Query: 109 LNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICIKFCDMPVFENSRAKSNG----M 164
LN +++ C G+ G SS G+ A + C +A +NG
Sbjct: 2548 LNSVVRWACDRGFRLV-GKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTT 2606
Query: 165 RFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSHFPTCYNSSEKCGPPPPISNGDTT 223
+ + + Y C DGY +S T + VC DG WS+ +N + +C ++
Sbjct: 2607 DYLVGTRVTYFCNDGYRLSSKELT-TAVCQSDGTWSN----HNKTPRC---VVVTCPSIN 2658
Query: 224 SFLLK----------VYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWS---EPPRC-IHP 268
SF+L+ Y +++V + C Y G + C NG WS E P C I
Sbjct: 2659 SFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIIS 2718
Query: 269 C--IITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGY 307
C + T N NK Q G T F C LG+
Sbjct: 2719 CGELPTPPNGNKIGTQ----------TSYGSTAIFTCDLGF 2749
Score = 38.1 bits (87), Expect = 0.011
Identities = 53/209 (25%), Positives = 80/209 (38%), Gaps = 35/209 (16%)
Query: 78 WSPTVPCLR--TCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCL 135
W VP + +C G ++ Y++ + Y C GY + + ++
Sbjct: 2580 WDAPVPACQAISCGIPKAPTNGGILTTD---YLVGTRVTYFCNDGYRLSSKELTTAVCQS 2636
Query: 136 QNGWS---AQPICI----KFCDMPVFENSRAK-SNGMRFKLHDTLDYECYDGYEISYGNT 187
WS P C+ + + E+ R + NG ++ + + C GY +G
Sbjct: 2637 DGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGY---HGLG 2693
Query: 188 TGSIVCGEDG-WS---HFPTCYNSSEKCG--PPPPISN--GDTTSFLLKVYVPQSRVEYQ 239
SI C +G WS P C S CG P PP N G TS+ S +
Sbjct: 2694 PASIECLPNGTWSWRNERPYCQIIS--CGELPTPPNGNKIGTQTSY-------GSTAIFT 2744
Query: 240 CQSYYELQGSNYVTC-SNGEWSE-PPRCI 266
C + L GS C S+G WSE RC+
Sbjct: 2745 CDLGFMLVGSAVRECLSSGLWSESETRCL 2773
Score = 36.6 bits (83), Expect = 0.032
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 5/43 (11%)
Query: 232 PQSRVEYQCQSYYELQGSNYVTCSNGE----WS-EPPRCIHPC 269
P V +QC YELQG +TC E W PP CI PC
Sbjct: 1506 PGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1548
Score = 34.3 bits (77), Expect = 0.16
Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 9/67 (13%)
Query: 209 EKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEWSEP------ 262
E C P I NG K+ S V Y C + Y LQG + +TC G+ P
Sbjct: 1659 ESCFDPGNIMNGTRLGMDYKL---GSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRAL 1715
Query: 263 PRCIHPC 269
P C PC
Sbjct: 1716 PSCHAPC 1722
Score = 33.5 bits (75), Expect = 0.27
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 4/44 (9%)
Query: 230 YVPQSRVEYQCQSYYELQGSNYVTCSNG---EWSEP-PRCIHPC 269
Y+ V +QC Y LQG +++TC G W+ P P C+ C
Sbjct: 2028 YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQC 2071
Score = 33.5 bits (75), Expect = 0.27
Identities = 28/111 (25%), Positives = 42/111 (37%), Gaps = 5/111 (4%)
Query: 211 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEWSE----PPRCI 266
C PPPP+ N + + + + + YQC + L G+ +TC GE + PP C
Sbjct: 2355 CQPPPPVPNAEILTEDDEFEIGDI-IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2413
Query: 267 HPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSFQ 317
C E ++ + L Y + GYN V FQ
Sbjct: 2414 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQ 2464
Score = 33.1 bits (74), Expect = 0.35
Identities = 35/140 (25%), Positives = 54/140 (38%), Gaps = 29/140 (20%)
Query: 136 QNGWSAQPIC-IKFCDMPVFENSRAKSNGMRFKLHDTLDYEC-YDGYEISYGNTTGSIVC 193
+NG QP+ + D+P N+ N R +L D+ Y+G+ I++
Sbjct: 1085 ENGSFTQPLARLTGSDLPPTINAGLYGN-FRAQLRFISDFSISYEGFNITFSE------- 1136
Query: 194 GEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVT 253
YN E C P G F + + + C S Y L+G++ +
Sbjct: 1137 -----------YNL-EPCEDPGIPQYGSRIGFNFGI---GDTLTFSCSSGYRLEGTSEII 1181
Query: 254 CSNG---EWSEP-PRCIHPC 269
C G WS P PRC+ C
Sbjct: 1182 CLGGGRRVWSAPLPRCVAEC 1201
Score = 31.2 bits (69), Expect = 1.3
Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 8/66 (12%)
Query: 163 GMRFKLHDTLDYECYDGYEISYGNTTGSIVCGED---GWSH-FPTCYNSSEKCGPPPPIS 218
GM +KL T+ Y C GY + G +T + + G+D GW+ P+C+ CG S
Sbjct: 1674 GMDYKLGSTVTYYCDAGY-VLQGYSTLTCIMGDDGRPGWNRALPSCH---APCGSRSTGS 1729
Query: 219 NGDTTS 224
G S
Sbjct: 1730 EGTVLS 1735
Score = 30.4 bits (67), Expect = 2.3
Identities = 16/40 (40%), Positives = 19/40 (47%), Gaps = 4/40 (10%)
Query: 234 SRVEYQCQSYYELQGSNYVTCSNGE---WSEP-PRCIHPC 269
S + Y C Y L GS+ + C GE W P P CI C
Sbjct: 1335 STIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAEC 1374
Score = 30.0 bits (66), Expect = 3.0
Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 209 EKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNG---EWSEP-PR 264
+ C P P NG + + ++C Y L G++ +TC +G W+ P PR
Sbjct: 2182 QSCPDPRPFRNGFVIG---NDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2238
Query: 265 CIHPC 269
C C
Sbjct: 2239 CEALC 2243
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 80.5 bits (197), Expect = 2e-15
Identities = 74/264 (28%), Positives = 111/264 (42%), Gaps = 23/264 (8%)
Query: 51 SYSYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVPCLRTCSKSDIEIENGFISESSSIYIL 109
S Y C + ++ S CT +G WS T+P S D I + Y++
Sbjct: 2967 SVIYSCMEGYILSGPSVRQ---CTANGTWSGTLPNCTIISCGDPGIPANGLRYGDD-YVV 3022
Query: 110 NKEIQYKCKPGYATADGNSSGSITCLQNG-WS-AQPIC-IKFCDMPVFENSRAKSNGMRF 166
+ + Y C+PGY T + N S TC NG WS P C C P + S + G F
Sbjct: 3023 GQNVSYMCQPGY-TMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPP-QISNGRLEGTNF 3080
Query: 167 KLHDTLDYECYDGYEISYGNTTGSIVCGEDGWS-HFPTCYNSSEKCGPPPPISNGDTTSF 225
++ Y C GYE+S+ + G WS P C + CG P + G
Sbjct: 3081 DWGFSISYICSPGYELSFPAVLTCV--GNGTWSGEVPQCL--PKFCGDPGIPAQGKREG- 3135
Query: 226 LLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWS-EPPRCIHPCIITEENMNKNNIQL 283
K ++ QS V + C + L GS+ C ++G WS P CI P T+ + +
Sbjct: 3136 --KSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEP---TQTSCENPGVPR 3190
Query: 284 KGKSDIKYYAKTGDTIEFMCKLGY 307
G + + + G ++F CK G+
Sbjct: 3191 HGSQNNTFGFQVGSVVQFHCKKGH 3214
Score = 60.5 bits (145), Expect = 2e-09
Identities = 87/300 (29%), Positives = 124/300 (41%), Gaps = 46/300 (15%)
Query: 24 CDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTP-SGSYWDYIHCTQDG-WSPT 81
C P I GL Y GQ+ SY C + +GS CT +G WS
Sbjct: 3004 CGDPGIPANGLRYGD------DYVVGQNVSYMCQPGYTMELNGSR--IRTCTINGTWSGV 3055
Query: 82 VPCLR--TCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG- 138
+P R TC +I NG + ++ + I Y C PGY + +TC+ NG
Sbjct: 3056 MPTCRAVTCPTPP-QISNGRLEGTN--FDWGFSISYICSPGYELS---FPAVLTCVGNGT 3109
Query: 139 WSAQ-PICI-KFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGED 196
WS + P C+ KFC P ++ K G F + + C + I G++T +C D
Sbjct: 3110 WSGEVPQCLPKFCGDPGIP-AQGKREGKSFIYQSEVSFSCNFPF-ILVGSSTR--ICQAD 3165
Query: 197 G-WS-HFPTCYN----SSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSN 250
G WS P C S E G P S +T F + S V++ C+ + LQGS
Sbjct: 3166 GTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVG-----SVVQFHCKKGHLLQGST 3220
Query: 251 YVTC-SNGEWSE-PPRCI-HPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGY 307
TC + WS P CI H C E + N + + S G T+ + C+ G+
Sbjct: 3221 TRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSH-------GYTLIYTCQPGF 3273
Score = 45.1 bits (105), Expect = 9e-05
Identities = 53/191 (27%), Positives = 79/191 (41%), Gaps = 25/191 (13%)
Query: 83 PCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQ 142
P + SK + +IE+G + + ++ Y C PGY S + C NG +
Sbjct: 2767 PGIPANSKRESKIEHGNFTYGTVVF-------YDCNPGYFLF---GSSVLICQPNGQWDK 2816
Query: 143 PI--CIKF-CDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-W 198
P+ CI C P + S G ++ T+ Y C G G + S C +G W
Sbjct: 2817 PLPECIMIDCGHPGVPPNAVLS-GEKYTFGSTVHYSC-TGKRSLLGQS--SRTCQLNGHW 2872
Query: 199 SHF-PTCY-NSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-S 255
S P C +++ CG P +G + +S V Y C + Y L GS TC +
Sbjct: 2873 SGSQPHCSGDATGTCGDPGTPGHGSRQESNFRT---KSTVRYACDTGYILHGSEERTCLA 2929
Query: 256 NGEWS-EPPRC 265
NG W+ P C
Sbjct: 2930 NGSWTGRQPEC 2940
Score = 42.0 bits (97), Expect = 8e-04
Identities = 51/172 (29%), Positives = 70/172 (40%), Gaps = 25/172 (14%)
Query: 109 LNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICIKFCDMPVFENSRAKSNG----M 164
LN +++ C G+ G SS G+ A + C +A +NG
Sbjct: 2484 LNSVVRWACDRGFRLV-GKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTT 2542
Query: 165 RFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSHF---PTCYNSSEKCG--PPPPIS 218
+ + + Y C DGY +S T + VC DG WS+ P C S CG P PP
Sbjct: 2543 DYLVGTRVTYFCNDGYRLSSKELT-TAVCQSDGTWSNHNKTPRCVVIS--CGELPTPPNG 2599
Query: 219 N--GDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWSE-PPRCI 266
N G TS+ S + C + L GS C S+G WSE RC+
Sbjct: 2600 NKIGTQTSY-------GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCL 2644
Score = 36.6 bits (83), Expect = 0.032
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 5/43 (11%)
Query: 232 PQSRVEYQCQSYYELQGSNYVTCSNGE----WS-EPPRCIHPC 269
P V +QC YELQG +TC E W PP CI PC
Sbjct: 1442 PGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1484
Score = 36.6 bits (83), Expect = 0.032
Identities = 54/246 (21%), Positives = 80/246 (32%), Gaps = 41/246 (16%)
Query: 78 WSPTVPCLR--TCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCL 135
W VP + +C G ++ Y++ + Y C GY + + ++
Sbjct: 2516 WDAPVPACQAISCGIPKAPTNGGILTTD---YLVGTRVTYFCNDGYRLSSKELTTAVCQS 2572
Query: 136 QNGWS---AQPICIKFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIV 192
WS P C+ + G + T + C G+ + GS V
Sbjct: 2573 DGTWSNHNKTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFML-----VGSAV 2627
Query: 193 --CGEDG-WSHFPT-CYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQG 248
C G WS T C + CG P I NG + Y + V YQC + L G
Sbjct: 2628 RECLSSGLWSESETRCL--AGHCGIPELIVNGQVIG---ENYGYRDTVVYQCNPGFRLIG 2682
Query: 249 SNYVTC-SNGEWS------EPPRCIHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEF 301
S+ C + WS P C HP + N D + F
Sbjct: 2683 SSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNF------------NDVVTF 2730
Query: 302 MCKLGY 307
C +GY
Sbjct: 2731 SCNIGY 2736
Score = 34.3 bits (77), Expect = 0.16
Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 9/67 (13%)
Query: 209 EKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEWSEP------ 262
E C P I NG K+ S V Y C + Y LQG + +TC G+ P
Sbjct: 1595 ESCFDPGNIMNGTRLGMDYKL---GSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRAL 1651
Query: 263 PRCIHPC 269
P C PC
Sbjct: 1652 PSCHAPC 1658
Score = 33.5 bits (75), Expect = 0.27
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 4/44 (9%)
Query: 230 YVPQSRVEYQCQSYYELQGSNYVTCSNG---EWSEP-PRCIHPC 269
Y+ V +QC Y LQG +++TC G W+ P P C+ C
Sbjct: 1964 YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQC 2007
Score = 33.5 bits (75), Expect = 0.27
Identities = 28/111 (25%), Positives = 42/111 (37%), Gaps = 5/111 (4%)
Query: 211 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEWSE----PPRCI 266
C PPPP+ N + + + + + YQC + L G+ +TC GE + PP C
Sbjct: 2291 CQPPPPVPNAEILTEDDEFEIGDI-IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2349
Query: 267 HPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSFQ 317
C E ++ + L Y + GYN V FQ
Sbjct: 2350 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQ 2400
Score = 33.1 bits (74), Expect = 0.35
Identities = 35/140 (25%), Positives = 54/140 (38%), Gaps = 29/140 (20%)
Query: 136 QNGWSAQPIC-IKFCDMPVFENSRAKSNGMRFKLHDTLDYEC-YDGYEISYGNTTGSIVC 193
+NG QP+ + D+P N+ N R +L D+ Y+G+ I++
Sbjct: 1021 ENGSFTQPLARLTGSDLPPTINAGLYGN-FRAQLRFISDFSISYEGFNITFSE------- 1072
Query: 194 GEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVT 253
YN E C P G F + + + C S Y L+G++ +
Sbjct: 1073 -----------YNL-EPCEDPGIPQYGSRIGFNFGI---GDTLTFSCSSGYRLEGTSEII 1117
Query: 254 CSNG---EWSEP-PRCIHPC 269
C G WS P PRC+ C
Sbjct: 1118 CLGGGRRVWSAPLPRCVAEC 1137
Score = 31.2 bits (69), Expect = 1.3
Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 8/66 (12%)
Query: 163 GMRFKLHDTLDYECYDGYEISYGNTTGSIVCGED---GWSH-FPTCYNSSEKCGPPPPIS 218
GM +KL T+ Y C GY + G +T + + G+D GW+ P+C+ CG S
Sbjct: 1610 GMDYKLGSTVTYYCDAGY-VLQGYSTLTCIMGDDGRPGWNRALPSCH---APCGSRSTGS 1665
Query: 219 NGDTTS 224
G S
Sbjct: 1666 EGTVLS 1671
Score = 30.4 bits (67), Expect = 2.3
Identities = 16/40 (40%), Positives = 19/40 (47%), Gaps = 4/40 (10%)
Query: 234 SRVEYQCQSYYELQGSNYVTCSNGE---WSEP-PRCIHPC 269
S + Y C Y L GS+ + C GE W P P CI C
Sbjct: 1271 STIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAEC 1310
Score = 30.0 bits (66), Expect = 3.0
Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 209 EKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNG---EWSEP-PR 264
+ C P P NG + + ++C Y L G++ +TC +G W+ P PR
Sbjct: 2118 QSCPDPRPFRNGFVIG---NDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2174
Query: 265 CIHPC 269
C C
Sbjct: 2175 CEALC 2179
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 80.5 bits (197), Expect = 2e-15
Identities = 74/264 (28%), Positives = 111/264 (42%), Gaps = 23/264 (8%)
Query: 51 SYSYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVPCLRTCSKSDIEIENGFISESSSIYIL 109
S Y C + ++ S CT +G WS T+P S D I + Y++
Sbjct: 3136 SVIYSCMEGYILSGPSVRQ---CTANGTWSGTLPNCTIISCGDPGIPANGLRYGDD-YVV 3191
Query: 110 NKEIQYKCKPGYATADGNSSGSITCLQNG-WS-AQPIC-IKFCDMPVFENSRAKSNGMRF 166
+ + Y C+PGY T + N S TC NG WS P C C P + S + G F
Sbjct: 3192 GQNVSYMCQPGY-TMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPP-QISNGRLEGTNF 3249
Query: 167 KLHDTLDYECYDGYEISYGNTTGSIVCGEDGWS-HFPTCYNSSEKCGPPPPISNGDTTSF 225
++ Y C GYE+S+ + G WS P C + CG P + G
Sbjct: 3250 DWGFSISYICSPGYELSFPAVLTCV--GNGTWSGEVPQCL--PKFCGDPGIPAQGKREG- 3304
Query: 226 LLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWS-EPPRCIHPCIITEENMNKNNIQL 283
K ++ QS V + C + L GS+ C ++G WS P CI P T+ + +
Sbjct: 3305 --KSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEP---TQTSCENPGVPR 3359
Query: 284 KGKSDIKYYAKTGDTIEFMCKLGY 307
G + + + G ++F CK G+
Sbjct: 3360 HGSQNNTFGFQVGSVVQFHCKKGH 3383
Score = 60.5 bits (145), Expect = 2e-09
Identities = 87/300 (29%), Positives = 124/300 (41%), Gaps = 46/300 (15%)
Query: 24 CDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTP-SGSYWDYIHCTQDG-WSPT 81
C P I GL Y GQ+ SY C + +GS CT +G WS
Sbjct: 3173 CGDPGIPANGLRYGD------DYVVGQNVSYMCQPGYTMELNGSR--IRTCTINGTWSGV 3224
Query: 82 VPCLR--TCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG- 138
+P R TC +I NG + ++ + I Y C PGY + +TC+ NG
Sbjct: 3225 MPTCRAVTCPTPP-QISNGRLEGTN--FDWGFSISYICSPGYELS---FPAVLTCVGNGT 3278
Query: 139 WSAQ-PICI-KFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGED 196
WS + P C+ KFC P ++ K G F + + C + I G++T +C D
Sbjct: 3279 WSGEVPQCLPKFCGDPGIP-AQGKREGKSFIYQSEVSFSCNFPF-ILVGSSTR--ICQAD 3334
Query: 197 G-WS-HFPTCYN----SSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSN 250
G WS P C S E G P S +T F + S V++ C+ + LQGS
Sbjct: 3335 GTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVG-----SVVQFHCKKGHLLQGST 3389
Query: 251 YVTC-SNGEWSE-PPRCI-HPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGY 307
TC + WS P CI H C E + N + + S G T+ + C+ G+
Sbjct: 3390 TRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSH-------GYTLIYTCQPGF 3442
Score = 45.1 bits (105), Expect = 9e-05
Identities = 53/191 (27%), Positives = 79/191 (41%), Gaps = 25/191 (13%)
Query: 83 PCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQ 142
P + SK + +IE+G + + ++ Y C PGY S + C NG +
Sbjct: 2936 PGIPANSKRESKIEHGNFTYGTVVF-------YDCNPGYFLF---GSSVLICQPNGQWDK 2985
Query: 143 PI--CIKF-CDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-W 198
P+ CI C P + S G ++ T+ Y C G G + S C +G W
Sbjct: 2986 PLPECIMIDCGHPGVPPNAVLS-GEKYTFGSTVHYSC-TGKRSLLGQS--SRTCQLNGHW 3041
Query: 199 SHF-PTCY-NSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-S 255
S P C +++ CG P +G + +S V Y C + Y L GS TC +
Sbjct: 3042 SGSQPHCSGDATGTCGDPGTPGHGSRQESNFRT---KSTVRYACDTGYILHGSEERTCLA 3098
Query: 256 NGEWS-EPPRC 265
NG W+ P C
Sbjct: 3099 NGSWTGRQPEC 3109
Score = 42.4 bits (98), Expect = 6e-04
Identities = 57/221 (25%), Positives = 85/221 (38%), Gaps = 41/221 (18%)
Query: 109 LNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICIKFCDMPVFENSRAKSNG----M 164
LN +++ C G+ G SS G+ A + C +A +NG
Sbjct: 2588 LNSVVRWACDRGFRLV-GKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTT 2646
Query: 165 RFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSHFPTCYNSSEKCGPPPPISNGDTT 223
+ + + Y C DGY +S T + VC DG WS+ +N + +C ++
Sbjct: 2647 DYLVGTRVTYFCNDGYRLSSKELT-TAVCQSDGTWSN----HNKTPRC---VVVTCPSIN 2698
Query: 224 SFLLK----------VYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWS---EPPRC-IHP 268
SF+L+ Y +++V + C Y G + C NG WS E P C I
Sbjct: 2699 SFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIIS 2758
Query: 269 C--IITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGY 307
C + T N NK Q G T F C LG+
Sbjct: 2759 CGELPTPPNGNKIGTQ----------TSYGSTAIFTCDLGF 2789
Score = 38.1 bits (87), Expect = 0.011
Identities = 53/209 (25%), Positives = 80/209 (38%), Gaps = 35/209 (16%)
Query: 78 WSPTVPCLR--TCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCL 135
W VP + +C G ++ Y++ + Y C GY + + ++
Sbjct: 2620 WDAPVPACQAISCGIPKAPTNGGILTTD---YLVGTRVTYFCNDGYRLSSKELTTAVCQS 2676
Query: 136 QNGWS---AQPICI----KFCDMPVFENSRAK-SNGMRFKLHDTLDYECYDGYEISYGNT 187
WS P C+ + + E+ R + NG ++ + + C GY +G
Sbjct: 2677 DGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGY---HGLG 2733
Query: 188 TGSIVCGEDG-WS---HFPTCYNSSEKCG--PPPPISN--GDTTSFLLKVYVPQSRVEYQ 239
SI C +G WS P C S CG P PP N G TS+ S +
Sbjct: 2734 PASIECLPNGTWSWRNERPYCQIIS--CGELPTPPNGNKIGTQTSY-------GSTAIFT 2784
Query: 240 CQSYYELQGSNYVTC-SNGEWSE-PPRCI 266
C + L GS C S+G WSE RC+
Sbjct: 2785 CDLGFMLVGSAVRECLSSGLWSESETRCL 2813
Score = 36.6 bits (83), Expect = 0.032
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 5/43 (11%)
Query: 232 PQSRVEYQCQSYYELQGSNYVTCSNGE----WS-EPPRCIHPC 269
P V +QC YELQG +TC E W PP CI PC
Sbjct: 1546 PGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1588
Score = 34.3 bits (77), Expect = 0.16
Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 9/67 (13%)
Query: 209 EKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEWSEP------ 262
E C P I NG K+ S V Y C + Y LQG + +TC G+ P
Sbjct: 1699 ESCFDPGNIMNGTRLGMDYKL---GSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRAL 1755
Query: 263 PRCIHPC 269
P C PC
Sbjct: 1756 PSCHAPC 1762
Score = 33.5 bits (75), Expect = 0.27
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 4/44 (9%)
Query: 230 YVPQSRVEYQCQSYYELQGSNYVTCSNG---EWSEP-PRCIHPC 269
Y+ V +QC Y LQG +++TC G W+ P P C+ C
Sbjct: 2068 YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQC 2111
Score = 33.5 bits (75), Expect = 0.27
Identities = 28/111 (25%), Positives = 42/111 (37%), Gaps = 5/111 (4%)
Query: 211 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEWSE----PPRCI 266
C PPPP+ N + + + + + YQC + L G+ +TC GE + PP C
Sbjct: 2395 CQPPPPVPNAEILTEDDEFEIGDI-IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2453
Query: 267 HPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSFQ 317
C E ++ + L Y + GYN V FQ
Sbjct: 2454 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQ 2504
Score = 33.1 bits (74), Expect = 0.35
Identities = 35/140 (25%), Positives = 54/140 (38%), Gaps = 29/140 (20%)
Query: 136 QNGWSAQPIC-IKFCDMPVFENSRAKSNGMRFKLHDTLDYEC-YDGYEISYGNTTGSIVC 193
+NG QP+ + D+P N+ N R +L D+ Y+G+ I++
Sbjct: 1125 ENGSFTQPLARLTGSDLPPTINAGLYGN-FRAQLRFISDFSISYEGFNITFSE------- 1176
Query: 194 GEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVT 253
YN E C P G F + + + C S Y L+G++ +
Sbjct: 1177 -----------YNL-EPCEDPGIPQYGSRIGFNFGI---GDTLTFSCSSGYRLEGTSEII 1221
Query: 254 CSNG---EWSEP-PRCIHPC 269
C G WS P PRC+ C
Sbjct: 1222 CLGGGRRVWSAPLPRCVAEC 1241
Score = 31.2 bits (69), Expect = 1.3
Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 8/66 (12%)
Query: 163 GMRFKLHDTLDYECYDGYEISYGNTTGSIVCGED---GWSH-FPTCYNSSEKCGPPPPIS 218
GM +KL T+ Y C GY + G +T + + G+D GW+ P+C+ CG S
Sbjct: 1714 GMDYKLGSTVTYYCDAGY-VLQGYSTLTCIMGDDGRPGWNRALPSCH---APCGSRSTGS 1769
Query: 219 NGDTTS 224
G S
Sbjct: 1770 EGTVLS 1775
Score = 30.4 bits (67), Expect = 2.3
Identities = 16/40 (40%), Positives = 19/40 (47%), Gaps = 4/40 (10%)
Query: 234 SRVEYQCQSYYELQGSNYVTCSNGE---WSEP-PRCIHPC 269
S + Y C Y L GS+ + C GE W P P CI C
Sbjct: 1375 STIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAEC 1414
Score = 30.0 bits (66), Expect = 3.0
Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 209 EKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNG---EWSEP-PR 264
+ C P P NG + + ++C Y L G++ +TC +G W+ P PR
Sbjct: 2222 QSCPDPRPFRNGFVIG---NDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2278
Query: 265 CIHPC 269
C C
Sbjct: 2279 CEALC 2283
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 78.2 bits (191), Expect = 1e-14
Identities = 71/251 (28%), Positives = 118/251 (47%), Gaps = 26/251 (10%)
Query: 72 HCTQDG-WSPTVPCLRTCSKSDI-EIENGFISESSSIYILNKEIQYKCKPGYATADGNSS 129
HCT +G W+ T P S D + NG + + + NK + Y+C PGY + +S
Sbjct: 3019 HCTANGTWTGTAPDCTIISCGDPGTLANGI--QFGTDFTFNKTVSYQCNPGYVM-EAVTS 3075
Query: 130 GSITCLQNG-WS-AQPIC--IKFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYG 185
+I C ++G W+ ++P+C + P +N + G F+ ++ Y C DGY++S+
Sbjct: 3076 ATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVE--GSDFRWGSSISYSCMDGYQLSH- 3132
Query: 186 NTTGSIVC-GEDGW-SHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSY 243
+ + C G W P C CG P + G + K + +S V +QC+S
Sbjct: 3133 --SAILSCEGRGVWKGEIPQCL--PVFCGDPGIPAEGRLSG---KSFTYKSEVFFQCKSP 3185
Query: 244 YELQGSNYVTC-SNGEWSE-PPRCIHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEF 301
+ L GS+ C ++G WS P CI P T + + ++ S + Y + G T+ F
Sbjct: 3186 FILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSS--RGY-EVGSTVFF 3242
Query: 302 MCKLGYNANTS 312
C+ GY+ S
Sbjct: 3243 RCRKGYHIQGS 3253
Score = 56.6 bits (135), Expect = 3e-08
Identities = 63/230 (27%), Positives = 100/230 (43%), Gaps = 21/230 (9%)
Query: 50 QSYSYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVP-CLRTCSKSDIEIENGFISESSSIY 107
++ SY C+ +V + + I CT+DG W+P+ P C ++NG + S +
Sbjct: 3058 KTVSYQCNPGYVMEAVTSAT-IRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSD--F 3114
Query: 108 ILNKEIQYKCKPGYATADGNSSGSITCLQNG-WSAQ-PICIK-FCDMPVFENSRAKSNGM 164
I Y C GY + S ++C G W + P C+ FC P + + +G
Sbjct: 3115 RWGSSISYSCMDGYQLSH---SAILSCEGRGVWKGEIPQCLPVFCGDPGIP-AEGRLSGK 3170
Query: 165 RFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSHF-PTCYNSSEKCGPPPPISNGDT 222
F + ++C + I G++ VC DG WS PTC + + P P +
Sbjct: 3171 SFTYKSEVFFQCKSPF-ILVGSSRR--VCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGI 3227
Query: 223 TSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWSE-PPRCI-HPC 269
+ + Y S V ++C+ Y +QGS TC +N WS CI H C
Sbjct: 3228 QNSS-RGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPHAC 3276
Score = 53.5 bits (127), Expect = 3e-07
Identities = 56/206 (27%), Positives = 84/206 (40%), Gaps = 24/206 (11%)
Query: 73 CTQDG-WSPT-VPCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSG 130
C +G WS + CL S I NG IS Y + Y+C PG+ +S
Sbjct: 2663 CLANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSY--RDTVVYQCNPGFRLV--GTSV 2718
Query: 131 SITCLQNGWSAQ-PICIKFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTG 189
I + WS Q P+C+ + +NG F L+D +++ C GY +
Sbjct: 2719 RICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLL---QGVS 2775
Query: 190 SIVCGEDG-WSH-FPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQS-----RVEYQCQS 242
C +G WS PTC C P + N + P+S + Y C+
Sbjct: 2776 RAQCRSNGQWSSPLPTC--RVVNCSDPGFVENAIRHG---QQNFPESFEYGMSILYHCKK 2830
Query: 243 YYELQGSNYVTC-SNGEWSEP-PRCI 266
+ L GS+ +TC +NG W P+C+
Sbjct: 2831 GFYLLGSSALTCMANGLWDRSLPKCL 2856
Score = 48.5 bits (114), Expect = 8e-06
Identities = 62/221 (28%), Positives = 89/221 (40%), Gaps = 41/221 (18%)
Query: 109 LNKEIQYKCKPGYATADGNSSGSITCLQNG-----W-SAQPICIKF-CDMPVFENSRAKS 161
+ ++ Y CKPGY G+S+ TC +N W S P+C C +P +
Sbjct: 2452 VGSKVHYFCKPGYRMV-GHSNA--TCRRNPLGMYQWDSLTPLCQAVSCGIPESPGN-GSF 2507
Query: 162 NGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSHF---PTCYNSSEKCGPPPPI 217
G F L + YEC++G+++ + + VC EDG WS+ PTC C P
Sbjct: 2508 TGNEFTLDSKVVYECHEGFKLE-SSQQATAVCQEDGLWSNKGKPPTC--KPVAC----PS 2560
Query: 218 SNGDTTSFLLKVYVPQSRVEY------QCQSYYELQGSNYVTC-SNGEWS---EPPRC-I 266
+ ++ V S EY C Y L+G + C +NG W+ E P C +
Sbjct: 2561 IEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRV 2620
Query: 267 HPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGY 307
C N N I + Y G T F C GY
Sbjct: 2621 ISCGSLSFPPNGNKI-----GTLTVY---GATAIFTCNTGY 2653
Score = 40.4 bits (93), Expect = 0.002
Identities = 50/222 (22%), Positives = 77/222 (34%), Gaps = 65/222 (29%)
Query: 107 YILNKEIQYKCKPGYATADGNSSGSITCLQNG---WS-AQPICIKFCD-----------M 151
Y++N + ++C+PGY T G S I+C+ W+ P+CI C
Sbjct: 1932 YMVNDVLSFQCEPGY-TLQGRSH--ISCMPGTVRRWNYPSPLCIATCGGTLSTLGGVILS 1988
Query: 152 PVFENSRAKSNGMRFKLHDTLDYECY------------DGYEISYGNTTGSIVCGEDGWS 199
P F S + +++ + Y + D EI G S + G+ +
Sbjct: 1989 PGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGT 2048
Query: 200 HFPTCYNSS----------------------------EKCGPPPPISNGDTTSFLLKVYV 231
P S+ + C PPP NG + Y
Sbjct: 2049 DLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPFQNG---YMINSDYS 2105
Query: 232 PQSRVEYQCQSYYELQGSNYVTCSNG---EWSEP-PRCIHPC 269
V ++C Y L G +TC +G W+ P PRC PC
Sbjct: 2106 VGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPC 2147
Score = 34.3 bits (77), Expect = 0.16
Identities = 21/73 (28%), Positives = 32/73 (43%), Gaps = 7/73 (9%)
Query: 201 FPTCYNSSEK--CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNG 257
F Y EK CG P + G T ++ + ++C + +EL G +TC N
Sbjct: 516 FKAVYQEIEKGGCGDPGIPAYGKRTG---SSFLHGDTLTFECPAAFELVGERVITCQQNN 572
Query: 258 EWS-EPPRCIHPC 269
+WS P C+ C
Sbjct: 573 QWSGNKPSCVFSC 585
Score = 34.3 bits (77), Expect = 0.16
Identities = 25/101 (24%), Positives = 40/101 (39%), Gaps = 6/101 (5%)
Query: 230 YVPQSRVEYQCQSYYELQGSNYVTCSNG---EWSEP-PRCIHPCIITEENMNKNNIQLKG 285
Y+ + +QC+ Y LQG ++++C G W+ P P CI C T + + L
Sbjct: 1932 YMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGGTLSTL--GGVILSP 1989
Query: 286 KSDIKYYAKTGDTIEFMCKLGYNANTSVLSFQAVCREGIVE 326
Y T +GY A+ L+F +E
Sbjct: 1990 GFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLE 2030
Score = 33.5 bits (75), Expect = 0.27
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 4/38 (10%)
Query: 236 VEYQCQSYYELQGSNYVTCSNGE---WSEP-PRCIHPC 269
V Y C Y + GSN +TC +G+ W +P P CI C
Sbjct: 1241 VLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAEC 1278
Score = 32.0 bits (71), Expect = 0.78
Identities = 26/96 (27%), Positives = 38/96 (39%), Gaps = 27/96 (28%)
Query: 179 GYEISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEY 238
G+ I + +T+ + C + G T Y S + G DT +F
Sbjct: 1379 GFSIQF-STSIAATCNDPGMPQNGTRYGDSREAG--------DTVTF------------- 1416
Query: 239 QCQSYYELQGSNYVTC----SNGEWS-EPPRCIHPC 269
QC Y+LQG +TC + W +PP CI C
Sbjct: 1417 QCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAAC 1452
Score = 32.0 bits (71), Expect = 0.78
Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 9/67 (13%)
Query: 209 EKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEWSEP------ 262
E C P I NG K+ S + YQC S Y++ + +TC G +P
Sbjct: 1563 EACFDPGNIMNGTRVGTDFKL---GSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVL 1619
Query: 263 PRCIHPC 269
P C PC
Sbjct: 1620 PSCNAPC 1626
Score = 29.6 bits (65), Expect = 3.9
Identities = 25/114 (21%), Positives = 41/114 (35%), Gaps = 5/114 (4%)
Query: 209 EKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEW----SEPPR 264
+KC PPP + + + + V+YQC Y L G++ +TC P
Sbjct: 2257 KKCQPPPAVPQAEMLTEDDDFEIGDF-VKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPT 2315
Query: 265 CIHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSFQA 318
C C E + + L Y+ + + YN V +FQ+
Sbjct: 2316 CEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQS 2369
Score = 29.3 bits (64), Expect = 5.1
Identities = 14/36 (38%), Positives = 19/36 (52%), Gaps = 4/36 (11%)
Query: 238 YQCQSYYELQGSNYVTCSNG---EWSEP-PRCIHPC 269
+ C Y L+G+ +TC G WS P PRC+ C
Sbjct: 1070 FSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAEC 1105
Score = 28.9 bits (63), Expect = 6.6
Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 6/42 (14%)
Query: 234 SRVEYQCQSYYELQGSNYVTCSN-----GEWSEP-PRCIHPC 269
S V ++C Y LQGS + C + +W++ P C+ PC
Sbjct: 1762 SIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVVPC 1803
Score = 28.5 bits (62), Expect = 8.7
Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 18/98 (18%)
Query: 163 GMRFKLHDTLDYECYDGYEISYGNTTGSIVC-----GEDGWSH-FPTC-------YNSSE 209
G FKL T+ Y+C GY+I SI C G+ W P+C Y SE
Sbjct: 1578 GTDFKLGSTITYQCDSGYKIL---DPSSITCVIGADGKPSWDQVLPSCNAPCGGQYTGSE 1634
Query: 210 KCGPPPPISNGDTTS--FLLKVYVPQSRVEYQCQSYYE 245
P + T L + VP+ V + +Y++
Sbjct: 1635 GVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQ 1672
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 74.7 bits (182), Expect = 1e-13
Identities = 71/226 (31%), Positives = 106/226 (46%), Gaps = 35/226 (15%)
Query: 53 SYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVPCLR--TCSKSDIEIENGFISESSSIYIL 109
+++C + ++ + C DG W +P + C + ++ +GF + S I+
Sbjct: 2914 TFHCHEGYILHGAPK---LTCQSDGNWDAEIPLCKPVNCGPPE-DLAHGFPNGFSFIH-- 2967
Query: 110 NKEIQYKCKPGYATADGNSSGSITCLQNG-WS-AQPICIKF-CDMPVFENSRAKSNGMRF 166
IQY+C PGY GNSS CL NG WS + P C+ C PV E NG F
Sbjct: 2968 GGHIQYQCFPGYKL-HGNSSRR--CLSNGSWSGSSPSCLPCRCSTPVIEYGTV--NGTDF 3022
Query: 167 KLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSH-FPTCYNSSEKCGPPPPISNG---D 221
+C+ G+++ I C DG WS FP C ++S CG P I N +
Sbjct: 3023 DCGKAARIQCFKGFKLL---GLSEITCEADGQWSSGFPHCEHTS--CGSLPMIPNAFISE 3077
Query: 222 TTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCS-NGEWSEP-PRC 265
T+S+ V + Y C+S Y +QGS+ + C+ G WS+P P C
Sbjct: 3078 TSSWKENV------ITYSCRSGYVIQGSSDLICTEKGVWSQPYPVC 3117
Score = 65.9 bits (159), Expect = 5e-11
Identities = 60/225 (26%), Positives = 88/225 (39%), Gaps = 40/225 (17%)
Query: 96 ENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WSAQPICIKFCDMPVF 154
ENG S IY + E+ + C+ GY ITCL++G W+ I +C
Sbjct: 1796 ENGH--SSGEIYTVGAEVTFSCQEGYQLM---GVTKITCLESGEWNH---LIPYCKAVSC 1847
Query: 155 ENSRAKSNG----MRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDGWSHF-PTCYNSSE 209
NG + F + Y C GY ++ G+ S + WSH P C
Sbjct: 1848 GKPAIPENGCIEELAFTFGSKVTYRCNKGYTLA-GDKESSCL-ANSSWSHSPPVC--EPV 1903
Query: 210 KCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWSEPPRCIH- 267
KC P I+NG ++L S Y C + Y LQG + + C ++G W P H
Sbjct: 1904 KCSSPENINNG---KYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHL 1960
Query: 268 -----PCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGY 307
P I + + NN + +T+ + CK GY
Sbjct: 1961 VFCGEPPAIKDAVITGNNFTFR------------NTVTYTCKEGY 1993
Score = 65.1 bits (157), Expect = 8e-11
Identities = 66/233 (28%), Positives = 89/233 (38%), Gaps = 29/233 (12%)
Query: 49 GQSYSYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVP-CLRTCSKSDIEIENGFISESSSI 106
G SY C+ + + C +DG W+ + P C+ ENGF+ + +
Sbjct: 2678 GTMVSYTCNPGYELLGNPV---LICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETS 2734
Query: 107 YILNKEIQYKCKPGYATADGNSSGSITCLQN-GWS-AQPICIKFCDMPVFENSRAKSNGM 164
+ +QY CKPG+ A S CL+N WS A P C G
Sbjct: 2735 --MGSAVQYSCKPGHILA---GSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGS 2789
Query: 165 RFKLHDTLDYECYDGYEISYGNTTGSIVCGED-GWSH-FPTCYNSSEKCGPPPPISNGDT 222
+ TL YEC GY + N T C +D W P C C PP +NG
Sbjct: 2790 NYTYLSTLYYECDPGYVL---NGTERRTCQDDKNWDEDEPICI--PVDCSSPPVSANGQV 2844
Query: 223 TSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWS------EPPRCIHP 268
Y Q +EY C + L+G+ C +NG WS P RC P
Sbjct: 2845 RG---DEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATP 2894
Score = 60.8 bits (146), Expect = 2e-09
Identities = 71/264 (26%), Positives = 110/264 (41%), Gaps = 28/264 (10%)
Query: 53 SYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVP-CLRTCSKSDIEIENGFISESSSIYILN 110
+Y C +V S D I CT+ G WS P C S + N + + Y
Sbjct: 3087 TYSCRSGYVIQGSS--DLI-CTEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAHTY--E 3141
Query: 111 KEIQYKCKPGYATADGNSSGSITCLQNG-WSAQPICIKFCDMPVFEN-SRAKSNGMRFKL 168
E++ +C GY T D ++ + TC ++G W + I P+ EN + +G F +
Sbjct: 3142 SEVKLRCLEGY-TMDTDTD-TFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSV 3199
Query: 169 HDTLDYECYDGYEISYGNTTGSIVCGEDGWSHFPTCYNSSE--KCGPPPPISNGDTTSFL 226
+ + C +GY N + VC DG P S CG P +G
Sbjct: 3200 NRQVSVSCAEGYTFEGVNIS---VCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVG-- 3254
Query: 227 LKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWSEPPRCIHPCIITEENMNKNNIQ-LK 284
Y +S + YQC+ YEL+G+ C N +WS I +E + ++ L
Sbjct: 3255 -SKYTFESTIIYQCEPGYELEGNRERVCQENRQWS------GGVAICKETRCETPLEFLN 3307
Query: 285 GKSDIKYYAKTGDTIEFMCKLGYN 308
GK+DI+ TG + + C GY+
Sbjct: 3308 GKADIE-NRTTGPNVVYSCNRGYS 3330
Score = 57.4 bits (137), Expect = 2e-08
Identities = 58/229 (25%), Positives = 91/229 (39%), Gaps = 26/229 (11%)
Query: 53 SYYCDQNFVTPSGSYWDYIHCTQDG-WSPT-VPCLRTCSKSDIEIENGFISESSSIYILN 110
+Y C + + D I C DG WS + CL +++ S ++ +
Sbjct: 1986 TYTCKEGYTLAG---LDTIECLADGKWSRSDQQCLAVSCDEPPIVDHA--SPETAHRLFG 2040
Query: 111 KEIQYKCKPGYATADGNSSGSITCLQNGW-----SAQPICIK-FCDMP--VFENSRAKSN 162
Y C GY+ AD +S + Q W P CI FC+ P V + +
Sbjct: 2041 DIAFYYCSDGYSLAD--NSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVS 2098
Query: 163 GMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSHFPTCYNSSE-KCGPPPPISNG 220
+F + ++C +G+ + NT+ I C G W+ P +CG PP I NG
Sbjct: 2099 KAKFAAGSVVSFKCMEGFVL---NTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNG 2155
Query: 221 DTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWSEPPRCIHP 268
+ Y + V Y C + ++G TC + G+WS P HP
Sbjct: 2156 YASG---SNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHP 2201
Score = 53.9 bits (128), Expect = 2e-07
Identities = 67/259 (25%), Positives = 95/259 (36%), Gaps = 33/259 (12%)
Query: 24 CDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDYIHCTQDG-WSPTV 82
C PE + G Y L L + + A SY CD + S I CT G W
Sbjct: 1905 CSSPENINNGKYI--LSGLTYLSTA----SYSCDTGYSLQGPSI---IECTASGIWDRAP 1955
Query: 83 P-CLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WS 140
P C I++ I+ ++ + + Y CK GY A +I CL +G WS
Sbjct: 1956 PACHLVFCGEPPAIKDAVITGNN--FTFRNTVTYTCKEGYTLA---GLDTIECLADGKWS 2010
Query: 141 A--QPICIKFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG- 197
Q CD P + + R D Y C DGY ++ ++C G
Sbjct: 2011 RSDQQCLAVSCDEPPIVDHASPETAHRL-FGDIAFYYCSDGYSLA---DNSQLLCNAQGK 2066
Query: 198 W-----SHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYV 252
W P C + C PP +S S + S V ++C + L S +
Sbjct: 2067 WVPPEGQDMPRCI--AHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKI 2124
Query: 253 TC-SNGEWSEPPRCIHPCI 270
C G+W+ P I CI
Sbjct: 2125 ECMRGGQWNPSPMSIQ-CI 2142
Score = 52.8 bits (125), Expect = 4e-07
Identities = 56/228 (24%), Positives = 96/228 (42%), Gaps = 26/228 (11%)
Query: 47 AAGQSYS------YYCDQNFVTPSGSYWDYIHCTQDGWSPTVPCLRTCSKSDIEIENGFI 100
A+G +YS Y C++ F G T SP C ++ENGF+
Sbjct: 2157 ASGSNYSFGAMVAYSCNKGFYI-KGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFL 2215
Query: 101 SESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQN-GWSAQP--ICIKF-CDM-PVFE 155
++ I E++Y+C PGY + S C N W ++ +C+ C P +
Sbjct: 2216 EHTTG-RIFESEVRYQCNPGYKSV---GSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQ 2271
Query: 156 NSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSHFPTCYNSSEKCGPP 214
N K G F++ + + C +GYE+ G++ S C + G W+ KC P
Sbjct: 2272 NGFMK--GENFEVGSKVQFFCNEGYEL-VGDS--SWTCQKSGKWNKKSNPKCMPAKCPEP 2326
Query: 215 PPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWSE 261
P + N L ++ V + C+ + LQG + + C + +W++
Sbjct: 2327 PLLEN---QLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWND 2371
Score = 52.0 bits (123), Expect = 7e-07
Identities = 55/231 (23%), Positives = 87/231 (37%), Gaps = 48/231 (20%)
Query: 49 GQSYSYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVPCLRT--CSKSDIEIENGFISESSS 105
G + Y C++ + S HCT++G WS VP + C + EN +SE
Sbjct: 3318 GPNVVYSCNRGYSLEGPSE---AHCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKE- 3373
Query: 106 IYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPI--CIKFCDMPVFENSRAKSNG 163
+ +++ + KC+ G+ G ITC + Q C K P A + G
Sbjct: 3374 -FYVDQNVSIKCREGFLL---QGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARG 3429
Query: 164 MRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSHFPTCYNSSEKCGPPPPISNGDT 222
+ ++ D + Y CY GY + + VC E+G W+ P C
Sbjct: 3430 VHYQYGDMITYSCYSGYMLEGFLRS---VCLENGTWTSPPIC------------------ 3468
Query: 223 TSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSN---GEWSEPPRCIHPCI 270
++ + CQ+ Q N +C G E P CI PC+
Sbjct: 3469 ----------RAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCL 3509
Score = 50.4 bits (119), Expect = 2e-06
Identities = 59/225 (26%), Positives = 84/225 (37%), Gaps = 23/225 (10%)
Query: 49 GQSYSYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVP-CLRTCSKSDIEIENGFISESSSI 106
G + Y C F S C DG WS +P C+ EI NG I
Sbjct: 2401 GSTVKYSCVGGFFLRGNST---TLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLA 2457
Query: 107 YILNKEIQYKCKPGYATADGNSSGSITCLQNG-W-SAQPICIKFCDMPVFENSRAKSNGM 164
Y+ Y CKPG+ GN++ C +NG W +P C + E K +
Sbjct: 2458 YL--STALYTCKPGFELV-GNTT--TLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYT 2512
Query: 165 RFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WS-HFPTCYNSSEKCGPPPPISNGDT 222
T+ Y C G+ + ++ C E G W P+C ++ C P PI NG
Sbjct: 2513 DLHYGQTVTYSCNRGFRLE---GPSALTCLETGDWDVDAPSC--NAIHCDSPQPIENGFV 2567
Query: 223 TSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEWSEP-PRCI 266
Y + + Y C +++ G TC WS P C+
Sbjct: 2568 EG---ADYSYGAIIIYSCFPGFQVAGHAMQTCEESGWSSSIPTCM 2609
Score = 50.1 bits (118), Expect = 3e-06
Identities = 48/197 (24%), Positives = 72/197 (36%), Gaps = 16/197 (8%)
Query: 78 WSPTVP-CLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQ 136
WS V C T ++ +E NG + + Y C GY+ +G S C +
Sbjct: 3287 WSGGVAICKETRCETPLEFLNGKADIENRT--TGPNVVYSCNRGYSL-EGPSEAH--CTE 3341
Query: 137 NGWSAQPICI---KFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVC 193
NG + P+ + C +P A + F + + +C +G+ + G I C
Sbjct: 3342 NGTWSHPVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQ---GHGIITC 3398
Query: 194 GEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVT 253
D + CGPP + N Y + Y C S Y L+G
Sbjct: 3399 NPDETWTQTSAKCEKISCGPPAHVENAIARGVH---YQYGDMITYSCYSGYMLEGFLRSV 3455
Query: 254 C-SNGEWSEPPRCIHPC 269
C NG W+ PP C C
Sbjct: 3456 CLENGTWTSPPICRAVC 3472
Score = 48.9 bits (115), Expect = 6e-06
Identities = 62/217 (28%), Positives = 90/217 (41%), Gaps = 42/217 (19%)
Query: 104 SSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WS-AQPICIKF-CDMPVFENSRAK 160
SS ++ + Y C PGY GN + C ++G W+ + P CI CD+P A
Sbjct: 2672 SSNFLYGTMVSYTCNPGYELL-GNP--VLICQEDGTWNGSAPSCISIECDLPT-----AP 2723
Query: 161 SNG-MRFKLHDTLDYECYDGYEISYGNTTGSIVCGED--------GWS-HFPTCYNSSEK 210
NG +RF E G + Y G I+ G D WS P C +
Sbjct: 2724 ENGFLRFT-------ETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRC--EAIS 2774
Query: 211 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGE-WSE-PPRCIHP 268
C P P+ NG S Y S + Y+C Y L G+ TC + + W E P CI P
Sbjct: 2775 CKKPNPVMNG---SIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICI-P 2830
Query: 269 CIITEENMNKNNIQLKG-----KSDIKYYAKTGDTIE 300
+ ++ N Q++G + +I+Y G +E
Sbjct: 2831 VDCSSPPVSANG-QVRGDEYTFQKEIEYTCNEGFLLE 2866
Score = 48.1 bits (113), Expect = 1e-05
Identities = 73/307 (23%), Positives = 113/307 (36%), Gaps = 75/307 (24%)
Query: 77 GWSPTVPCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQ 136
G PT + C K EI NG S + Y + + Y C G+ ++TCL+
Sbjct: 2488 GGKPTCKAIE-CLKPK-EILNGKFSYTDLHY--GQTVTYSCNRGFRL---EGPSALTCLE 2540
Query: 137 NG-WSAQ-PICIKF-CDMPV-FENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIV 192
G W P C CD P EN + G + + Y C+ G++++ G+ +
Sbjct: 2541 TGDWDVDAPSCNAIHCDSPQPIENGFVE--GADYSYGAIIIYSCFPGFQVA-GHAMQT-- 2595
Query: 193 CGEDGWSH-FPTCYNSSEKCGPPPPISNGDTTSF------------LLKV---------- 229
C E GWS PTC CG PP I GD T +++V
Sbjct: 2596 CEESGWSSSIPTCMPID--CGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYH 2653
Query: 230 ---------------------YVPQSRVEYQCQSYYELQGSNYVTC-SNGEWS-EPPRCI 266
++ + V Y C YEL G+ + C +G W+ P CI
Sbjct: 2654 LGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCI 2713
Query: 267 HPCIITEENMNKNNIQLKGKSDIKYYAKT--GDTIEFMCKLGYNANTSVLSFQAVCREGI 324
+ ++ ++ + +T G +++ CK G+ S L R+
Sbjct: 2714 ---------SIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWS 2764
Query: 325 VEYPRCE 331
PRCE
Sbjct: 2765 GASPRCE 2771
Score = 45.4 bits (106), Expect = 7e-05
Identities = 52/170 (30%), Positives = 77/170 (45%), Gaps = 21/170 (12%)
Query: 104 SSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WSAQ-PICIKF-CDMPV-FENSRA 159
SS ++Y C G+ GNS+ C +G WS+ P C+ C P N
Sbjct: 2395 SSALHFGSTVKYSCVGGFFLR-GNST--TLCQPDGTWSSPLPECVPVECPQPEEIPNGII 2451
Query: 160 KSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-W-SHFPTCYNSSEKCGPPPPI 217
G+ + T Y C G+E+ GNTT +CGE+G W PTC + +C P I
Sbjct: 2452 DVQGLAYL--STALYTCKPGFEL-VGNTT--TLCGENGHWLGGKPTC--KAIECLKPKEI 2504
Query: 218 SNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWS-EPPRC 265
NG + ++ Q+ V Y C + L+G + +TC G+W + P C
Sbjct: 2505 LNGKFS--YTDLHYGQT-VTYSCNRGFRLEGPSALTCLETGDWDVDAPSC 2551
Score = 43.1 bits (100), Expect = 3e-04
Identities = 51/225 (22%), Positives = 81/225 (36%), Gaps = 52/225 (23%)
Query: 49 GQSYSYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVP-CLRTCSKSDIEIENGFISESSSI 106
G + +CD F +C G W+ +P C R +ENGF S+
Sbjct: 1651 GSKVNLFCDPGFQLVGNPVQ---YCLNQGQWTQPLPHCERISCGVPPPLENGF--HSADD 1705
Query: 107 YILNKEIQYKCKPGYATADGNSSGSITCLQNG-WSA-QPICIKFCDMPVFENSRAKSNGM 164
+ + Y+C GY + C NG W+ P C+ + V + ++ +
Sbjct: 1706 FYAGSTVTYQCNNGYYLL---GDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCL 1762
Query: 165 RFKLHDTLDYECYDGYEISYGNTTGSIVCG------EDGWSHFPTCYNSSE--KCGPPPP 216
N GS +C DG N +E KC P
Sbjct: 1763 ---------------------NVDGSYICSCVPPYTGDG-------KNCAEPIKCKAPGN 1794
Query: 217 ISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWS 260
NG ++ ++Y + V + CQ Y+L G +TC +GEW+
Sbjct: 1795 PENGHSSG---EIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWN 1836
Score = 43.1 bits (100), Expect = 3e-04
Identities = 50/182 (27%), Positives = 75/182 (41%), Gaps = 22/182 (12%)
Query: 87 TCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WSAQPIC 145
+C K + E+GF+ S Y I Y+C+PGY +GN C +N WS
Sbjct: 3240 SCGKPESP-EHGFVVGSK--YTFESTIIYQCEPGYEL-EGNRER--VCQENRQWSGGVAI 3293
Query: 146 IKF--CDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSH-F 201
K C+ P+ E K++ + Y C GY + + C E+G WSH
Sbjct: 3294 CKETRCETPL-EFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAH---CTENGTWSHPV 3349
Query: 202 PTCYNSSEKCGP-PPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGE-W 259
P C K P P P + K + V +C+ + LQG +TC+ E W
Sbjct: 3350 PLC-----KPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETW 3404
Query: 260 SE 261
++
Sbjct: 3405 TQ 3406
Score = 38.1 bits (87), Expect = 0.011
Identities = 24/67 (35%), Positives = 34/67 (50%), Gaps = 7/67 (10%)
Query: 202 PTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCS-NGEWS 260
P C S CG PPP+ NG ++ + S V YQC + Y L G + + C+ NG W+
Sbjct: 1683 PHCERIS--CGVPPPLENGFHSA---DDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWN 1737
Query: 261 -EPPRCI 266
P C+
Sbjct: 1738 GVSPSCL 1744
Score = 30.4 bits (67), Expect = 2.3
Identities = 13/29 (44%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
Query: 240 CQSYYELQGSNYVTC-SNGEWSEP-PRCI 266
C Y L+GS+ +TC N +W P PRC+
Sbjct: 466 CDEGYRLEGSDKLTCQGNSQWDGPEPRCV 494
>gi|54792123 complement component (3d/Epstein Barr virus) receptor 2
isoform 1 [Homo sapiens]
Length = 1092
Score = 70.1 bits (170), Expect = 3e-12
Identities = 63/240 (26%), Positives = 105/240 (43%), Gaps = 25/240 (10%)
Query: 45 PAAAGQSYSYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVPCLRTCSKSDIEIENGFISES 103
P + ++ C F S I C D W P +P +S + +G +
Sbjct: 619 PYFYNDTVTFKCYSGFTLKGSSQ---IRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGG 675
Query: 104 SSIYILN-KEIQYKCKPGYATADGNSSGSITCLQNG-WS-AQPICIKFCDMPVFENSRAK 160
++++ ++ + Y C PGY GN S I C+ +G WS + P C + C V ++ +
Sbjct: 676 NTVFFVSGMTVDYTCDPGYLLV-GNKS--IHCMPSGNWSPSAPRCEETCQH-VRQSLQEL 731
Query: 161 SNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG--WSHFPTCYNSSEKCGPPPPIS 218
G R +L +T C DGY+++ G+ E+G + P C C PPP I
Sbjct: 732 PAGSRVELVNT---SCQDGYQLT-GHAYQMCQDAENGIWFKKIPLC--KVIHCHPPPVIV 785
Query: 219 NGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-----SNGEWSEP-PRCIHPCIIT 272
NG T + + ++ + V Y+C + L G + C +G WS P P+C+ +T
Sbjct: 786 NGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVT 845
Score = 54.3 bits (129), Expect = 1e-07
Identities = 66/254 (25%), Positives = 96/254 (37%), Gaps = 27/254 (10%)
Query: 95 IENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITC--LQNGWSAQ-PICIKF--- 148
I NG IS S+ + I+Y C + S IT + W P C F
Sbjct: 29 ILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKY 88
Query: 149 --CDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGED---GWSHFPT 203
C P+ ++ D++ + C + + N S+ C + G + PT
Sbjct: 89 SSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSM---NGNKSVWCQANNMWGPTRLPT 145
Query: 204 CYNSSE-KCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWSE 261
C + +C P I NG TS + P V Y C+S Y L G + C S+G+WS
Sbjct: 146 CVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSA 205
Query: 262 -PPRCIHPCIITEENMNKNNIQL-KGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSFQAV 319
PP C EE K+ + GK + G T F C GY S +
Sbjct: 206 VPPTC-------EEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVI 258
Query: 320 CREGI--VEYPRCE 331
+G+ + P CE
Sbjct: 259 AGQGVAWTKMPVCE 272
Score = 51.6 bits (122), Expect = 1e-06
Identities = 60/233 (25%), Positives = 92/233 (39%), Gaps = 28/233 (12%)
Query: 49 GQSYSYYCDQNFVTPSGSYWDYIHCTQDG-----WS-PTVPCLRTCSKS---DIEIENGF 99
G SY CDQ F + C D WS P+ CLR+ + + E+++G+
Sbjct: 800 GNEVSYECDQGFYLLGEKK---LQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGY 856
Query: 100 -ISESSSIYILNKEIQYKCKPGYATADGNSSGSITC-LQNGW-SAQPICIKF----CDMP 152
++++ S Y N + C PG+ N S I C N W P CIK C P
Sbjct: 857 KLNKTHSAYSHNDIVYVDCNPGFIM---NGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPP 913
Query: 153 --VFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDGWSHFPTCYNSSEK 210
+ N RF ++ Y C GY + G ++C +G P +
Sbjct: 914 PKTPNGNHTGGNIARFSPGMSILYSCDQGY-LLVGEAL--LLCTHEGTWSQPAPHCKEVN 970
Query: 211 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWSEP 262
C P + K+Y + V +C+ Y L+GS C S+ +W+ P
Sbjct: 971 CSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPP 1023
Score = 50.4 bits (119), Expect = 2e-06
Identities = 60/253 (23%), Positives = 94/253 (37%), Gaps = 37/253 (14%)
Query: 78 WSPTVPCLRT--CSKSDIEIENGFISESSSIYILNKEIQYKCKPGY---------ATADG 126
W +P + C + + + ++ E+ Y+C G+ +D
Sbjct: 766 WFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDS 825
Query: 127 NSSGSITCLQNGWSA-QPICIKFCDMPVFENSRAKSNGMRFKLH------DTLDYECYDG 179
GS WS P C++ + N K K H D + +C G
Sbjct: 826 KGHGS-------WSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPG 878
Query: 180 YEISYGNTTGSIVCGEDG-W-SHFPTCYNSSE-KCGPPPPISNGDTTSFLLKVYVPQSRV 236
+ + N + I C D W PTC + C PPP NG+ T + + P +
Sbjct: 879 FIM---NGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSI 935
Query: 237 EYQCQSYYELQGSNYVTCSN-GEWSEP-PRCIHPCIITEENMNKNNIQLKGKSDIKYYAK 294
Y C Y L G + C++ G WS+P P C + +M + IQ KG K Y +
Sbjct: 936 LYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADM--DGIQ-KGLEPRKMY-Q 991
Query: 295 TGDTIEFMCKLGY 307
G + C+ GY
Sbjct: 992 YGAVVTLECEDGY 1004
Score = 48.5 bits (114), Expect = 8e-06
Identities = 59/268 (22%), Positives = 98/268 (36%), Gaps = 45/268 (16%)
Query: 71 IHCTQDG-WSPTVPCLRTCSKSDIEIENGFISESSSI-YILNKEIQYKCKPGYATADGNS 128
I C G W P+ P ++ I NG + + + I+Y C PGY
Sbjct: 391 IRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV---G 447
Query: 129 SGSITCLQNGWSAQPICIKFCDMPVFENSRAKSNGMRFK-------LHDTLDYECYDGYE 181
SI C G P+ P + + ++ G + + ++ C +GY+
Sbjct: 448 EESIQCTSEGVWTPPV-------PQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYK 500
Query: 182 IS---YGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEY 238
+S Y G+I + C + C PPP I NG T L+ + + V Y
Sbjct: 501 LSGSVYQECQGTI----PWFMEIRLCKEIT--CPPPPVIYNGAHTGSSLEDFPYGTTVTY 554
Query: 239 QCQS------YYELQGSNYVTCSN-----GEWSEPPRCIHPCIITEENMN---KNNIQLK 284
C + L G + + C++ G WS P ++ + + N ++
Sbjct: 555 TCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKIS 614
Query: 285 GKSDIKYYAKTGDTIEFMCKLGYNANTS 312
GK +Y DT+ F C G+ S
Sbjct: 615 GKEAPYFY---NDTVTFKCYSGFTLKGS 639
Score = 45.8 bits (107), Expect = 5e-05
Identities = 71/282 (25%), Positives = 106/282 (37%), Gaps = 33/282 (11%)
Query: 47 AAGQSYSYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVP-CLRTCSKSDIEIENGFISESS 104
A G S +Y C+ ++ I+C G WS P C KS NG + E
Sbjct: 174 APGLSVTYSCESGYLLVGEKI---INCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPP 230
Query: 105 SIYILNKEIQYKCKPGYATADGNSSGSITCLQN-GWSAQPICIK-FCDMPV-FENSRAKS 161
+ + + C GY SS + Q W+ P+C + FC P N R
Sbjct: 231 ILRV-GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIG 289
Query: 162 NGMRFKLHDTL-DYECYDGYE-----ISYGNTTGSIVCGEDG-----WSH-FPTCY--NS 207
N + + ++ Y C E I G +T + C D WS P C S
Sbjct: 290 NSLANVSYGSIVTYTCDPDPEEGVNFILIGEST--LRCTVDSQKTGTWSGPAPRCELSTS 347
Query: 208 SEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWS-EPPRC 265
+ +C P P I G S Y V + C + L+GS + C + G W P C
Sbjct: 348 AVQC-PHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVC 406
Query: 266 IHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGY 307
C + N N Q + + +++ G +I++ C GY
Sbjct: 407 EKEC---QAPPNILNGQKEDRHMVRF--DPGTSIKYSCNPGY 443
Score = 44.3 bits (103), Expect = 2e-04
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 8/104 (7%)
Query: 165 RFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSHFPTCYNSSEKCGPPPPISNGDTT 223
R+ +DT+ + C G+ + I C G W P+ ++C PP I NG
Sbjct: 368 RYTYNDTVIFACMFGFTLKGSK---QIRCNAQGTWE--PSAPVCEKECQAPPNILNGQKE 422
Query: 224 SFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWSEP-PRC 265
+ + P + ++Y C Y L G + C S G W+ P P+C
Sbjct: 423 DRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC 466
Score = 43.1 bits (100), Expect = 3e-04
Identities = 35/130 (26%), Positives = 56/130 (43%), Gaps = 16/130 (12%)
Query: 211 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-----SNGEWSEP-PR 264
CG PPPI NG + + + V + + Y C + L G + C +G W +P P+
Sbjct: 23 CGSPPPILNGRISYYSTPIAV-GTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 265 C--IHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGY--NANTSVLSFQAVC 320
C + E + +++G + ++ GD++ F CK + N N SV QA
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRH----GDSVTFACKTNFSMNGNKSVWC-QANN 136
Query: 321 REGIVEYPRC 330
G P C
Sbjct: 137 MWGPTRLPTC 146
Score = 37.0 bits (84), Expect = 0.024
Identities = 64/286 (22%), Positives = 103/286 (36%), Gaps = 50/286 (17%)
Query: 49 GQSYSYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVPCLRTCSKSDIEIENGFISESSSIY 107
G S Y C+ +V + I CT +G W+P VP C + E +
Sbjct: 432 GTSIKYSCNPGYVLVGE---ESIQCTSEGVWTPPVP---QCKVAACEATGRQLLTKPQHQ 485
Query: 108 ILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICIKFCDM------PVFENSRAKS 161
+ ++ C GY SGS+ G + I+ C PV N
Sbjct: 486 FVRPDVNSSCGEGYKL-----SGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTG 540
Query: 162 NGMR-FKLHDTLDYECYDGYEISYGNTTGSIVCGEDGWSHFPTCYNSSEK---CGPPP-- 215
+ + F T+ Y C G E S++ G S N E+ GP P
Sbjct: 541 SSLEDFPYGTTVTYTCNPGPE---RGVEFSLI----GESTIRCTSNDQERGTWSGPAPLC 593
Query: 216 ------------PISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWS-E 261
I+NG S Y V ++C S + L+GS+ + C ++ W E
Sbjct: 594 KLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPE 653
Query: 262 PPRCIHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGY 307
P C C + ++ + G + + + +G T+++ C GY
Sbjct: 654 IPVCEKGC---QSPPGLHHGRHTGGNTV--FFVSGMTVDYTCDPGY 694
>gi|86793109 complement receptor 1 isoform S precursor [Homo
sapiens]
Length = 2489
Score = 67.8 bits (164), Expect = 1e-11
Identities = 60/208 (28%), Positives = 89/208 (42%), Gaps = 26/208 (12%)
Query: 78 WSPTVP-CLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQ 136
W P +P C R C + + +E+ Y C+PGY D + S+ C
Sbjct: 286 WEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY---DLRGAASMRCTP 342
Query: 137 NG-WS-AQPIC-IKFCD--MPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSI 191
G WS A P C +K CD M N R + +L +D+ C +G+++ + + +
Sbjct: 343 QGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP-VNLQLGAKVDFVCDEGFQLKGSSASYCV 401
Query: 192 VCG-EDGW-SHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSY------ 243
+ G E W S P C C PP I NG T L+V+ V Y C +
Sbjct: 402 LAGMESLWNSSVPVCEQIF--CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTS 459
Query: 244 YELQGSNYVTCS-----NGEWSEP-PRC 265
++L G + + C+ NG WS P PRC
Sbjct: 460 FDLIGESTIRCTSDPQGNGVWSSPAPRC 487
Score = 67.8 bits (164), Expect = 1e-11
Identities = 60/208 (28%), Positives = 89/208 (42%), Gaps = 26/208 (12%)
Query: 78 WSPTVP-CLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQ 136
W P +P C R C + + +E+ Y C+PGY D + S+ C
Sbjct: 736 WEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY---DLRGAASMRCTP 792
Query: 137 NG-WS-AQPIC-IKFCD--MPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSI 191
G WS A P C +K CD M N R + +L +D+ C +G+++ + + +
Sbjct: 793 QGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP-VNLQLGAKVDFVCDEGFQLKGSSASYCV 851
Query: 192 VCG-EDGW-SHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSY------ 243
+ G E W S P C C PP I NG T L+V+ V Y C +
Sbjct: 852 LAGMESLWNSSVPVCEQIF--CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTS 909
Query: 244 YELQGSNYVTCS-----NGEWSEP-PRC 265
++L G + + C+ NG WS P PRC
Sbjct: 910 FDLIGESTIRCTSDPQGNGVWSSPAPRC 937
Score = 67.8 bits (164), Expect = 1e-11
Identities = 60/208 (28%), Positives = 89/208 (42%), Gaps = 26/208 (12%)
Query: 78 WSPTVP-CLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQ 136
W P +P C R C + + +E+ Y C+PGY D + S+ C
Sbjct: 1186 WEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY---DLRGAASMRCTP 1242
Query: 137 NG-WS-AQPIC-IKFCD--MPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSI 191
G WS A P C +K CD M N R + +L +D+ C +G+++ + + +
Sbjct: 1243 QGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP-VNLQLGAKVDFVCDEGFQLKGSSASYCV 1301
Query: 192 VCG-EDGW-SHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSY------ 243
+ G E W S P C C PP I NG T L+V+ V Y C +
Sbjct: 1302 LAGMESLWNSSVPVCEQIF--CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTS 1359
Query: 244 YELQGSNYVTCS-----NGEWSEP-PRC 265
++L G + + C+ NG WS P PRC
Sbjct: 1360 FDLIGESTIRCTSDPQGNGVWSSPAPRC 1387
Score = 63.9 bits (154), Expect = 2e-10
Identities = 70/276 (25%), Positives = 109/276 (39%), Gaps = 34/276 (12%)
Query: 11 LWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNF-VTPSGSYWD 69
+W S + K C P G+ + + + G + +Y C++ F + S S
Sbjct: 1894 VWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQF-----GSTVNYSCNEGFRLIGSPSTTC 1948
Query: 70 YIHCTQDGWSPTVPCLRTCS-KSDIEIENG-FISESSSIYILNKEIQYKCKPGYATADGN 127
+ W P S + I NG F S + + + + Y+C G DG
Sbjct: 1949 LVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTG---PDGE 2005
Query: 128 S------SGSITCLQNG-----WSAQP---ICIKFCDMPVFENS-RAKSNGMRFKLHDTL 172
SI C WS+ P I C P EN+ R N F L + +
Sbjct: 2006 QLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEII 2065
Query: 173 DYECYDGYEISYGNTTGSIVCGEDG-WSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYV 231
+ C G+ + +T + C +G W P + S C PPP I +G+ T +
Sbjct: 2066 RFRCQPGFVMVGSHT---VQCQTNGRWG--PKLPHCSRVCQPPPEILHGEHTLSHQDNFS 2120
Query: 232 PQSRVEYQCQSYYELQGSNYVTCS-NGEWS-EPPRC 265
P V Y C+ Y+L+G+ + C+ G+WS E PRC
Sbjct: 2121 PGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRC 2156
Score = 60.5 bits (145), Expect = 2e-09
Identities = 60/215 (27%), Positives = 92/215 (42%), Gaps = 33/215 (15%)
Query: 113 IQYKCKPGYATADGNSSGSITCLQNG-WSAQPICIKFCDMPVFENSRAKSNGM-----RF 166
+ Y+C+PGY+ SI CL+N W+ C N NGM
Sbjct: 69 LNYECRPGYS----GRPFSIICLKNSVWTGAK---DRCRRKSCRNPPDPVNGMVHVIKGI 121
Query: 167 KLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSH-FPTCYNSSEKCGPPPPISNGDTTS 224
+ + Y C GY + ++ I+ G+ W + P C CG PP I+NGD S
Sbjct: 122 QFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC--DRIPCGLPPTITNGDFIS 179
Query: 225 FLLKVYVPQSRVEYQC------QSYYELQGSNYVTCSN-----GEWSEP-PRCIHPCIIT 272
+ + S V Y+C + +EL G + C++ G WS P P+CI P T
Sbjct: 180 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT 239
Query: 273 EENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGY 307
N+ +N I + SD + + +EF C+ G+
Sbjct: 240 PPNV-ENGILV---SDNRSLFSLNEVVEFRCQPGF 270
Score = 58.5 bits (140), Expect = 8e-09
Identities = 66/257 (25%), Positives = 102/257 (39%), Gaps = 29/257 (11%)
Query: 78 WSPTVP-CLRTCSKSDIEIENG-FISESSSIYILNKEIQYKCKPGYA---TADGNSSGSI 132
WS P C R I NG FIS + + + Y+C PG + SI
Sbjct: 604 WSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSI 663
Query: 133 TCLQNG-----WSAQ-PICI--KFCDMPVFENSRAKS-NGMRFKLHDTLDYECYDGYEIS 183
C N WS P CI C P EN S N F L++ +++ C G+ +
Sbjct: 664 YCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMK 723
Query: 184 YGNTTGSIVCGEDGWS-HFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQS 242
+ W P+C S C PPP + + + T + P V Y C+
Sbjct: 724 GPRRVKCQALNK--WEPELPSC---SRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEP 778
Query: 243 YYELQGSNYVTCS-NGEWS-EPPRC-IHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTI 299
Y+L+G+ + C+ G+WS P C + C ++ M + L G+ + G +
Sbjct: 779 GYDLRGAASMRCTPQGDWSPAAPTCEVKSC---DDFMGQ---LLNGRVLFPVNLQLGAKV 832
Query: 300 EFMCKLGYNANTSVLSF 316
+F+C G+ S S+
Sbjct: 833 DFVCDEGFQLKGSSASY 849
Score = 58.5 bits (140), Expect = 8e-09
Identities = 66/257 (25%), Positives = 102/257 (39%), Gaps = 29/257 (11%)
Query: 78 WSPTVP-CLRTCSKSDIEIENG-FISESSSIYILNKEIQYKCKPGYA---TADGNSSGSI 132
WS P C R I NG FIS + + + Y+C PG + SI
Sbjct: 1054 WSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSI 1113
Query: 133 TCLQNG-----WSAQ-PICI--KFCDMPVFENSRAKS-NGMRFKLHDTLDYECYDGYEIS 183
C N WS P CI C P EN S N F L++ +++ C G+ +
Sbjct: 1114 YCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMK 1173
Query: 184 YGNTTGSIVCGEDGWS-HFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQS 242
+ W P+C S C PPP + + + T + P V Y C+
Sbjct: 1174 GPRRVKCQALNK--WEPELPSC---SRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEP 1228
Query: 243 YYELQGSNYVTCS-NGEWS-EPPRC-IHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTI 299
Y+L+G+ + C+ G+WS P C + C ++ M + L G+ + G +
Sbjct: 1229 GYDLRGAASMRCTPQGDWSPAAPTCEVKSC---DDFMGQ---LLNGRVLFPVNLQLGAKV 1282
Query: 300 EFMCKLGYNANTSVLSF 316
+F+C G+ S S+
Sbjct: 1283 DFVCDEGFQLKGSSASY 1299
Score = 57.8 bits (138), Expect = 1e-08
Identities = 59/205 (28%), Positives = 83/205 (40%), Gaps = 22/205 (10%)
Query: 78 WSPTVP-CLRTCSKSDIEIENG-FISESSSIYILNKEIQYKCK---PGYATADGNSSGSI 132
WS P C R I NG FIS + + + Y+C G + SI
Sbjct: 1504 WSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSI 1563
Query: 133 TCLQNG-----WSAQ-PICI--KFCDMPVFENSRAKS-NGMRFKLHDTLDYECYDGYEIS 183
C N WS P CI C P EN S N F L++ +++ C G+ +
Sbjct: 1564 YCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMK 1623
Query: 184 YGNTTGSIVCGEDGWS-HFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQS 242
+ W P+C S C PPP I +G+ T + P V Y C+
Sbjct: 1624 GPRRVKCQALNK--WEPELPSC---SRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEP 1678
Query: 243 YYELQGSNYVTCS-NGEWS-EPPRC 265
Y+L+G+ + C+ G+WS E PRC
Sbjct: 1679 GYDLRGAASLHCTPQGDWSPEAPRC 1703
Score = 57.0 bits (136), Expect = 2e-08
Identities = 61/239 (25%), Positives = 97/239 (40%), Gaps = 28/239 (11%)
Query: 95 IENG-FISESSSIYILNKEIQYKCKPGYA---TADGNSSGSITCLQNG-----WSAQ-PI 144
I NG FIS + + + Y+C PG + SI C N WS P
Sbjct: 172 ITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 231
Query: 145 CI--KFCDMPVFENSRAKS-NGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDGWS-H 200
CI C P EN S N F L++ +++ C G+ + + W
Sbjct: 232 CIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK--WEPE 289
Query: 201 FPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCS-NGEW 259
P+C S C PPP + + + T + P V Y C+ Y+L+G+ + C+ G+W
Sbjct: 290 LPSC---SRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDW 346
Query: 260 S-EPPRC-IHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSF 316
S P C + C ++ M + L G+ + G ++F+C G+ S S+
Sbjct: 347 SPAAPTCEVKSC---DDFMGQ---LLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASY 399
Score = 54.3 bits (129), Expect = 1e-07
Identities = 82/320 (25%), Positives = 127/320 (39%), Gaps = 60/320 (18%)
Query: 27 PEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVP-- 83
PEI HG + S + + P GQ Y C+ ++ + +HCT G WSP P
Sbjct: 2104 PEILHGE-HTLSHQDNFSP---GQEVFYSCEPSYDLRGAAS---LHCTPQGDWSPEAPRC 2156
Query: 84 CLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITC-LQNGW-SA 141
+++C ++ +G + ++ L ++ + C G+ ++S + ++ W S+
Sbjct: 2157 TVKSCDDFLGQLPHGRVLLPLNLQ-LGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSS 2215
Query: 142 QPICIK-FC-DMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTT----------- 188
P+C + FC + P N R G F + Y G EISY T
Sbjct: 2216 VPVCEQIFCPNPPAILNGR--HTGTPF---GDIPY----GKEISYACDTHPDRGMTFNLI 2266
Query: 189 --GSIVCGEDG-----WSH-FPTCYNS-SEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQ 239
SI C D WS P C S C PP I NG + +Y+P + Y
Sbjct: 2267 GESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYI 2326
Query: 240 CQSYYELQGSNYVTCSN-GEWSE------PPRCIHPCIITEENMNKNNIQLKGKSDIKYY 292
C Y L G ++ C++ G WS+ C P MN + +L+ K Y
Sbjct: 2327 CDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLF-----MNGISKELEMKKVYHY- 2380
Query: 293 AKTGDTIEFMCKLGYNANTS 312
GD + C+ GY S
Sbjct: 2381 ---GDYVTLKCEDGYTLEGS 2397
Score = 50.4 bits (119), Expect = 2e-06
Identities = 93/334 (27%), Positives = 120/334 (35%), Gaps = 77/334 (23%)
Query: 21 VKPCD--FPEIQHGGLYYKSLRRLYFPA--AAGQSYSYYCDQNFVTPSGSYWDYIHCTQD 76
VK CD ++ HG R+ FP G S+ CD+ F S HC
Sbjct: 1705 VKSCDDFLGQLPHG--------RVLFPLNLQLGAKVSFVCDEGFRLKGSSV---SHCVLV 1753
Query: 77 G----WSPTVP-CLRTCSKSDIEIENGFISESSSIYI-LNKEIQYKCKPGY---ATADGN 127
G W+ +VP C + I NG + + S I KEI Y C P T +
Sbjct: 1754 GMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLI 1813
Query: 128 SSGSITCLQ----NG-WSAQ-PIC-----IKFCDMPV---FENSRAKSNGMRFKLHDTLD 173
+I C NG WS+ P C C P F + N F + +L+
Sbjct: 1814 GESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLN 1873
Query: 174 YECYDGYEISYGNTTGSIVCGED-GWSHF-PTCYNSSEKCGPPPPISNG-----DTTSFL 226
YEC GY +G SI C E+ WS C S CGPPP NG T F
Sbjct: 1874 YECRPGY---FGKMF-SISCLENLVWSSVEDNCRRKS--CGPPPEPFNGMVHINTDTQF- 1926
Query: 227 LKVYVPQSRVEYQCQSYYELQGSNYVTC----SNGEWS-----------EPPRCIHPCII 271
S V Y C + L GS TC +N W EPP P I
Sbjct: 1927 ------GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPP----PTIS 1976
Query: 272 TEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKL 305
+ + N + + Y TG E + +L
Sbjct: 1977 NGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFEL 2010
Score = 32.7 bits (73), Expect = 0.46
Identities = 68/267 (25%), Positives = 96/267 (35%), Gaps = 37/267 (13%)
Query: 21 VKPCD--FPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDYIHCTQDG- 77
VK CD ++ HG + +L G S+ CD+ F S HC G
Sbjct: 2158 VKSCDDFLGQLPHGRVLLPLNLQL------GAKVSFVCDEGFRLKGRSA---SHCVLAGM 2208
Query: 78 ---WSPTVP-CLRTCSKSDIEIENGFISESSSIYI-LNKEIQYKCKPGY---ATADGNSS 129
W+ +VP C + + I NG + + I KEI Y C T +
Sbjct: 2209 KALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGE 2268
Query: 130 GSITCLQ----NG-WSAQ-PICIKFCDM-----PVFENSRAKSNGMRFKLHD-TLDYECY 177
SI C NG WS+ P C P +N + L T+ Y C
Sbjct: 2269 SSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICD 2328
Query: 178 DGYEISYGNTTGSIVCGEDG-WSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRV 236
GY + G I C + G WS Y C P ++ + KVY V
Sbjct: 2329 PGYLLV---GKGFIFCTDQGIWSQLDH-YCKEVNCSFPLFMNGISKELEMKKVYHYGDYV 2384
Query: 237 EYQCQSYYELQGSNYVTCSNGEWSEPP 263
+C+ Y L+GS + C + +PP
Sbjct: 2385 TLKCEDGYTLEGSPWSQCQADDRWDPP 2411
>gi|86793036 complement receptor 1 isoform F precursor [Homo
sapiens]
Length = 2039
Score = 67.8 bits (164), Expect = 1e-11
Identities = 60/208 (28%), Positives = 89/208 (42%), Gaps = 26/208 (12%)
Query: 78 WSPTVP-CLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQ 136
W P +P C R C + + +E+ Y C+PGY D + S+ C
Sbjct: 286 WEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY---DLRGAASMRCTP 342
Query: 137 NG-WS-AQPIC-IKFCD--MPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSI 191
G WS A P C +K CD M N R + +L +D+ C +G+++ + + +
Sbjct: 343 QGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP-VNLQLGAKVDFVCDEGFQLKGSSASYCV 401
Query: 192 VCG-EDGW-SHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSY------ 243
+ G E W S P C C PP I NG T L+V+ V Y C +
Sbjct: 402 LAGMESLWNSSVPVCEQIF--CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTS 459
Query: 244 YELQGSNYVTCS-----NGEWSEP-PRC 265
++L G + + C+ NG WS P PRC
Sbjct: 460 FDLIGESTIRCTSDPQGNGVWSSPAPRC 487
Score = 67.8 bits (164), Expect = 1e-11
Identities = 60/208 (28%), Positives = 89/208 (42%), Gaps = 26/208 (12%)
Query: 78 WSPTVP-CLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQ 136
W P +P C R C + + +E+ Y C+PGY D + S+ C
Sbjct: 736 WEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY---DLRGAASMRCTP 792
Query: 137 NG-WS-AQPIC-IKFCD--MPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSI 191
G WS A P C +K CD M N R + +L +D+ C +G+++ + + +
Sbjct: 793 QGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP-VNLQLGAKVDFVCDEGFQLKGSSASYCV 851
Query: 192 VCG-EDGW-SHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSY------ 243
+ G E W S P C C PP I NG T L+V+ V Y C +
Sbjct: 852 LAGMESLWNSSVPVCEQIF--CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTS 909
Query: 244 YELQGSNYVTCS-----NGEWSEP-PRC 265
++L G + + C+ NG WS P PRC
Sbjct: 910 FDLIGESTIRCTSDPQGNGVWSSPAPRC 937
Score = 63.9 bits (154), Expect = 2e-10
Identities = 70/276 (25%), Positives = 109/276 (39%), Gaps = 34/276 (12%)
Query: 11 LWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNF-VTPSGSYWD 69
+W S + K C P G+ + + + G + +Y C++ F + S S
Sbjct: 1444 VWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQF-----GSTVNYSCNEGFRLIGSPSTTC 1498
Query: 70 YIHCTQDGWSPTVPCLRTCS-KSDIEIENG-FISESSSIYILNKEIQYKCKPGYATADGN 127
+ W P S + I NG F S + + + + Y+C G DG
Sbjct: 1499 LVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTG---PDGE 1555
Query: 128 S------SGSITCLQNG-----WSAQP---ICIKFCDMPVFENS-RAKSNGMRFKLHDTL 172
SI C WS+ P I C P EN+ R N F L + +
Sbjct: 1556 QLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEII 1615
Query: 173 DYECYDGYEISYGNTTGSIVCGEDG-WSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYV 231
+ C G+ + +T + C +G W P + S C PPP I +G+ T +
Sbjct: 1616 RFRCQPGFVMVGSHT---VQCQTNGRWG--PKLPHCSRVCQPPPEILHGEHTLSHQDNFS 1670
Query: 232 PQSRVEYQCQSYYELQGSNYVTCS-NGEWS-EPPRC 265
P V Y C+ Y+L+G+ + C+ G+WS E PRC
Sbjct: 1671 PGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRC 1706
Score = 60.5 bits (145), Expect = 2e-09
Identities = 60/215 (27%), Positives = 92/215 (42%), Gaps = 33/215 (15%)
Query: 113 IQYKCKPGYATADGNSSGSITCLQNG-WSAQPICIKFCDMPVFENSRAKSNGM-----RF 166
+ Y+C+PGY+ SI CL+N W+ C N NGM
Sbjct: 69 LNYECRPGYS----GRPFSIICLKNSVWTGAK---DRCRRKSCRNPPDPVNGMVHVIKGI 121
Query: 167 KLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSH-FPTCYNSSEKCGPPPPISNGDTTS 224
+ + Y C GY + ++ I+ G+ W + P C CG PP I+NGD S
Sbjct: 122 QFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC--DRIPCGLPPTITNGDFIS 179
Query: 225 FLLKVYVPQSRVEYQC------QSYYELQGSNYVTCSN-----GEWSEP-PRCIHPCIIT 272
+ + S V Y+C + +EL G + C++ G WS P P+CI P T
Sbjct: 180 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT 239
Query: 273 EENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGY 307
N+ +N I + SD + + +EF C+ G+
Sbjct: 240 PPNV-ENGILV---SDNRSLFSLNEVVEFRCQPGF 270
Score = 58.5 bits (140), Expect = 8e-09
Identities = 66/257 (25%), Positives = 102/257 (39%), Gaps = 29/257 (11%)
Query: 78 WSPTVP-CLRTCSKSDIEIENG-FISESSSIYILNKEIQYKCKPGYA---TADGNSSGSI 132
WS P C R I NG FIS + + + Y+C PG + SI
Sbjct: 604 WSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSI 663
Query: 133 TCLQNG-----WSAQ-PICI--KFCDMPVFENSRAKS-NGMRFKLHDTLDYECYDGYEIS 183
C N WS P CI C P EN S N F L++ +++ C G+ +
Sbjct: 664 YCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMK 723
Query: 184 YGNTTGSIVCGEDGWS-HFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQS 242
+ W P+C S C PPP + + + T + P V Y C+
Sbjct: 724 GPRRVKCQALNK--WEPELPSC---SRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEP 778
Query: 243 YYELQGSNYVTCS-NGEWS-EPPRC-IHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTI 299
Y+L+G+ + C+ G+WS P C + C ++ M + L G+ + G +
Sbjct: 779 GYDLRGAASMRCTPQGDWSPAAPTCEVKSC---DDFMGQ---LLNGRVLFPVNLQLGAKV 832
Query: 300 EFMCKLGYNANTSVLSF 316
+F+C G+ S S+
Sbjct: 833 DFVCDEGFQLKGSSASY 849
Score = 57.8 bits (138), Expect = 1e-08
Identities = 59/205 (28%), Positives = 83/205 (40%), Gaps = 22/205 (10%)
Query: 78 WSPTVP-CLRTCSKSDIEIENG-FISESSSIYILNKEIQYKCK---PGYATADGNSSGSI 132
WS P C R I NG FIS + + + Y+C G + SI
Sbjct: 1054 WSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSI 1113
Query: 133 TCLQNG-----WSAQ-PICI--KFCDMPVFENSRAKS-NGMRFKLHDTLDYECYDGYEIS 183
C N WS P CI C P EN S N F L++ +++ C G+ +
Sbjct: 1114 YCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMK 1173
Query: 184 YGNTTGSIVCGEDGWS-HFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQS 242
+ W P+C S C PPP I +G+ T + P V Y C+
Sbjct: 1174 GPRRVKCQALNK--WEPELPSC---SRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEP 1228
Query: 243 YYELQGSNYVTCS-NGEWS-EPPRC 265
Y+L+G+ + C+ G+WS E PRC
Sbjct: 1229 GYDLRGAASLHCTPQGDWSPEAPRC 1253
Score = 57.0 bits (136), Expect = 2e-08
Identities = 61/239 (25%), Positives = 97/239 (40%), Gaps = 28/239 (11%)
Query: 95 IENG-FISESSSIYILNKEIQYKCKPGYA---TADGNSSGSITCLQNG-----WSAQ-PI 144
I NG FIS + + + Y+C PG + SI C N WS P
Sbjct: 172 ITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 231
Query: 145 CI--KFCDMPVFENSRAKS-NGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDGWS-H 200
CI C P EN S N F L++ +++ C G+ + + W
Sbjct: 232 CIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK--WEPE 289
Query: 201 FPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCS-NGEW 259
P+C S C PPP + + + T + P V Y C+ Y+L+G+ + C+ G+W
Sbjct: 290 LPSC---SRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDW 346
Query: 260 S-EPPRC-IHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSF 316
S P C + C ++ M + L G+ + G ++F+C G+ S S+
Sbjct: 347 SPAAPTCEVKSC---DDFMGQ---LLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASY 399
Score = 54.3 bits (129), Expect = 1e-07
Identities = 82/320 (25%), Positives = 127/320 (39%), Gaps = 60/320 (18%)
Query: 27 PEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVP-- 83
PEI HG + S + + P GQ Y C+ ++ + +HCT G WSP P
Sbjct: 1654 PEILHGE-HTLSHQDNFSP---GQEVFYSCEPSYDLRGAAS---LHCTPQGDWSPEAPRC 1706
Query: 84 CLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITC-LQNGW-SA 141
+++C ++ +G + ++ L ++ + C G+ ++S + ++ W S+
Sbjct: 1707 TVKSCDDFLGQLPHGRVLLPLNLQ-LGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSS 1765
Query: 142 QPICIK-FC-DMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTT----------- 188
P+C + FC + P N R G F + Y G EISY T
Sbjct: 1766 VPVCEQIFCPNPPAILNGR--HTGTPF---GDIPY----GKEISYACDTHPDRGMTFNLI 1816
Query: 189 --GSIVCGEDG-----WSH-FPTCYNS-SEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQ 239
SI C D WS P C S C PP I NG + +Y+P + Y
Sbjct: 1817 GESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYI 1876
Query: 240 CQSYYELQGSNYVTCSN-GEWSE------PPRCIHPCIITEENMNKNNIQLKGKSDIKYY 292
C Y L G ++ C++ G WS+ C P MN + +L+ K Y
Sbjct: 1877 CDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLF-----MNGISKELEMKKVYHY- 1930
Query: 293 AKTGDTIEFMCKLGYNANTS 312
GD + C+ GY S
Sbjct: 1931 ---GDYVTLKCEDGYTLEGS 1947
Score = 50.4 bits (119), Expect = 2e-06
Identities = 93/334 (27%), Positives = 120/334 (35%), Gaps = 77/334 (23%)
Query: 21 VKPCD--FPEIQHGGLYYKSLRRLYFPA--AAGQSYSYYCDQNFVTPSGSYWDYIHCTQD 76
VK CD ++ HG R+ FP G S+ CD+ F S HC
Sbjct: 1255 VKSCDDFLGQLPHG--------RVLFPLNLQLGAKVSFVCDEGFRLKGSSV---SHCVLV 1303
Query: 77 G----WSPTVP-CLRTCSKSDIEIENGFISESSSIYI-LNKEIQYKCKPGY---ATADGN 127
G W+ +VP C + I NG + + S I KEI Y C P T +
Sbjct: 1304 GMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLI 1363
Query: 128 SSGSITCLQ----NG-WSAQ-PIC-----IKFCDMPV---FENSRAKSNGMRFKLHDTLD 173
+I C NG WS+ P C C P F + N F + +L+
Sbjct: 1364 GESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLN 1423
Query: 174 YECYDGYEISYGNTTGSIVCGED-GWSHF-PTCYNSSEKCGPPPPISNG-----DTTSFL 226
YEC GY +G SI C E+ WS C S CGPPP NG T F
Sbjct: 1424 YECRPGY---FGKMF-SISCLENLVWSSVEDNCRRKS--CGPPPEPFNGMVHINTDTQF- 1476
Query: 227 LKVYVPQSRVEYQCQSYYELQGSNYVTC----SNGEWS-----------EPPRCIHPCII 271
S V Y C + L GS TC +N W EPP P I
Sbjct: 1477 ------GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPP----PTIS 1526
Query: 272 TEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKL 305
+ + N + + Y TG E + +L
Sbjct: 1527 NGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFEL 1560
Score = 32.7 bits (73), Expect = 0.46
Identities = 68/267 (25%), Positives = 96/267 (35%), Gaps = 37/267 (13%)
Query: 21 VKPCD--FPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDYIHCTQDG- 77
VK CD ++ HG + +L G S+ CD+ F S HC G
Sbjct: 1708 VKSCDDFLGQLPHGRVLLPLNLQL------GAKVSFVCDEGFRLKGRSA---SHCVLAGM 1758
Query: 78 ---WSPTVP-CLRTCSKSDIEIENGFISESSSIYI-LNKEIQYKCKPGY---ATADGNSS 129
W+ +VP C + + I NG + + I KEI Y C T +
Sbjct: 1759 KALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGE 1818
Query: 130 GSITCLQ----NG-WSAQ-PICIKFCDM-----PVFENSRAKSNGMRFKLHD-TLDYECY 177
SI C NG WS+ P C P +N + L T+ Y C
Sbjct: 1819 SSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICD 1878
Query: 178 DGYEISYGNTTGSIVCGEDG-WSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRV 236
GY + G I C + G WS Y C P ++ + KVY V
Sbjct: 1879 PGYLLV---GKGFIFCTDQGIWSQLDH-YCKEVNCSFPLFMNGISKELEMKKVYHYGDYV 1934
Query: 237 EYQCQSYYELQGSNYVTCSNGEWSEPP 263
+C+ Y L+GS + C + +PP
Sbjct: 1935 TLKCEDGYTLEGSPWSQCQADDRWDPP 1961
>gi|42544177 complement component (3d/Epstein Barr virus) receptor 2
isoform 2 [Homo sapiens]
Length = 1033
Score = 67.8 bits (164), Expect = 1e-11
Identities = 61/222 (27%), Positives = 93/222 (41%), Gaps = 29/222 (13%)
Query: 71 IHCTQDG-----WSPTVPC----LRTCSKSDIEIENGF-ISESSSIYILNKEIQYKCKPG 120
I CT + WS P L S + I NG+ IS + Y N + +KC G
Sbjct: 574 IRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSG 633
Query: 121 YATADGNSSGSITC-LQNGWSAQ-PICIKFCDMPVFENSRAKSNGMRFKLHDTLDYECYD 178
+ S I C N W + P+C K V ++ + G R +L +T C D
Sbjct: 634 FTL---KGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNT---SCQD 687
Query: 179 GYEISYGNTTGSIVCGEDG--WSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRV 236
GY+++ G+ E+G + P C C PPP I NG T + + ++ + V
Sbjct: 688 GYQLT-GHAYQMCQDAENGIWFKKIPLC--KVIHCHPPPVIVNGKHTGMMAENFLYGNEV 744
Query: 237 EYQCQSYYELQGSNYVTC-----SNGEWSEP-PRCIHPCIIT 272
Y+C + L G + C +G WS P P+C+ +T
Sbjct: 745 SYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVT 786
Score = 54.3 bits (129), Expect = 1e-07
Identities = 66/254 (25%), Positives = 96/254 (37%), Gaps = 27/254 (10%)
Query: 95 IENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITC--LQNGWSAQ-PICIKF--- 148
I NG IS S+ + I+Y C + S IT + W P C F
Sbjct: 29 ILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKY 88
Query: 149 --CDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGED---GWSHFPT 203
C P+ ++ D++ + C + + N S+ C + G + PT
Sbjct: 89 SSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSM---NGNKSVWCQANNMWGPTRLPT 145
Query: 204 CYNSSE-KCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWSE 261
C + +C P I NG TS + P V Y C+S Y L G + C S+G+WS
Sbjct: 146 CVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSA 205
Query: 262 -PPRCIHPCIITEENMNKNNIQL-KGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSFQAV 319
PP C EE K+ + GK + G T F C GY S +
Sbjct: 206 VPPTC-------EEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVI 258
Query: 320 CREGI--VEYPRCE 331
+G+ + P CE
Sbjct: 259 AGQGVAWTKMPVCE 272
Score = 51.6 bits (122), Expect = 1e-06
Identities = 60/233 (25%), Positives = 92/233 (39%), Gaps = 28/233 (12%)
Query: 49 GQSYSYYCDQNFVTPSGSYWDYIHCTQDG-----WS-PTVPCLRTCSKS---DIEIENGF 99
G SY CDQ F + C D WS P+ CLR+ + + E+++G+
Sbjct: 741 GNEVSYECDQGFYLLGEKK---LQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGY 797
Query: 100 -ISESSSIYILNKEIQYKCKPGYATADGNSSGSITC-LQNGW-SAQPICIKF----CDMP 152
++++ S Y N + C PG+ N S I C N W P CIK C P
Sbjct: 798 KLNKTHSAYSHNDIVYVDCNPGFIM---NGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPP 854
Query: 153 --VFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDGWSHFPTCYNSSEK 210
+ N RF ++ Y C GY + G ++C +G P +
Sbjct: 855 PKTPNGNHTGGNIARFSPGMSILYSCDQGY-LLVGEAL--LLCTHEGTWSQPAPHCKEVN 911
Query: 211 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWSEP 262
C P + K+Y + V +C+ Y L+GS C S+ +W+ P
Sbjct: 912 CSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPP 964
Score = 50.4 bits (119), Expect = 2e-06
Identities = 60/253 (23%), Positives = 94/253 (37%), Gaps = 37/253 (14%)
Query: 78 WSPTVPCLRT--CSKSDIEIENGFISESSSIYILNKEIQYKCKPGY---------ATADG 126
W +P + C + + + ++ E+ Y+C G+ +D
Sbjct: 707 WFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDS 766
Query: 127 NSSGSITCLQNGWSA-QPICIKFCDMPVFENSRAKSNGMRFKLH------DTLDYECYDG 179
GS WS P C++ + N K K H D + +C G
Sbjct: 767 KGHGS-------WSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPG 819
Query: 180 YEISYGNTTGSIVCGEDG-W-SHFPTCYNSSE-KCGPPPPISNGDTTSFLLKVYVPQSRV 236
+ + N + I C D W PTC + C PPP NG+ T + + P +
Sbjct: 820 FIM---NGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSI 876
Query: 237 EYQCQSYYELQGSNYVTCSN-GEWSEP-PRCIHPCIITEENMNKNNIQLKGKSDIKYYAK 294
Y C Y L G + C++ G WS+P P C + +M + IQ KG K Y +
Sbjct: 877 LYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADM--DGIQ-KGLEPRKMY-Q 932
Query: 295 TGDTIEFMCKLGY 307
G + C+ GY
Sbjct: 933 YGAVVTLECEDGY 945
Score = 48.5 bits (114), Expect = 8e-06
Identities = 59/268 (22%), Positives = 98/268 (36%), Gaps = 45/268 (16%)
Query: 71 IHCTQDG-WSPTVPCLRTCSKSDIEIENGFISESSSI-YILNKEIQYKCKPGYATADGNS 128
I C G W P+ P ++ I NG + + + I+Y C PGY
Sbjct: 391 IRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV---G 447
Query: 129 SGSITCLQNGWSAQPICIKFCDMPVFENSRAKSNGMRFK-------LHDTLDYECYDGYE 181
SI C G P+ P + + ++ G + + ++ C +GY+
Sbjct: 448 EESIQCTSEGVWTPPV-------PQCKVAACEATGRQLLTKPQHQFVRPDVNSSCGEGYK 500
Query: 182 IS---YGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEY 238
+S Y G+I + C + C PPP I NG T L+ + + V Y
Sbjct: 501 LSGSVYQECQGTI----PWFMEIRLCKEIT--CPPPPVIYNGAHTGSSLEDFPYGTTVTY 554
Query: 239 QCQS------YYELQGSNYVTCSN-----GEWSEPPRCIHPCIITEENMN---KNNIQLK 284
C + L G + + C++ G WS P ++ + + N ++
Sbjct: 555 TCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKIS 614
Query: 285 GKSDIKYYAKTGDTIEFMCKLGYNANTS 312
GK +Y DT+ F C G+ S
Sbjct: 615 GKEAPYFY---NDTVTFKCYSGFTLKGS 639
Score = 45.8 bits (107), Expect = 5e-05
Identities = 71/282 (25%), Positives = 106/282 (37%), Gaps = 33/282 (11%)
Query: 47 AAGQSYSYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVP-CLRTCSKSDIEIENGFISESS 104
A G S +Y C+ ++ I+C G WS P C KS NG + E
Sbjct: 174 APGLSVTYSCESGYLLVGEKI---INCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPP 230
Query: 105 SIYILNKEIQYKCKPGYATADGNSSGSITCLQN-GWSAQPICIK-FCDMPV-FENSRAKS 161
+ + + C GY SS + Q W+ P+C + FC P N R
Sbjct: 231 ILRV-GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIG 289
Query: 162 NGMRFKLHDTL-DYECYDGYE-----ISYGNTTGSIVCGEDG-----WSH-FPTCY--NS 207
N + + ++ Y C E I G +T + C D WS P C S
Sbjct: 290 NSLANVSYGSIVTYTCDPDPEEGVNFILIGEST--LRCTVDSQKTGTWSGPAPRCELSTS 347
Query: 208 SEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWS-EPPRC 265
+ +C P P I G S Y V + C + L+GS + C + G W P C
Sbjct: 348 AVQC-PHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVC 406
Query: 266 IHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGY 307
C + N N Q + + +++ G +I++ C GY
Sbjct: 407 EKEC---QAPPNILNGQKEDRHMVRF--DPGTSIKYSCNPGY 443
Score = 44.3 bits (103), Expect = 2e-04
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 8/104 (7%)
Query: 165 RFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSHFPTCYNSSEKCGPPPPISNGDTT 223
R+ +DT+ + C G+ + I C G W P+ ++C PP I NG
Sbjct: 368 RYTYNDTVIFACMFGFTLKGSK---QIRCNAQGTWE--PSAPVCEKECQAPPNILNGQKE 422
Query: 224 SFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWSEP-PRC 265
+ + P + ++Y C Y L G + C S G W+ P P+C
Sbjct: 423 DRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC 466
Score = 43.1 bits (100), Expect = 3e-04
Identities = 35/130 (26%), Positives = 56/130 (43%), Gaps = 16/130 (12%)
Query: 211 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-----SNGEWSEP-PR 264
CG PPPI NG + + + V + + Y C + L G + C +G W +P P+
Sbjct: 23 CGSPPPILNGRISYYSTPIAV-GTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 265 C--IHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGY--NANTSVLSFQAVC 320
C + E + +++G + ++ GD++ F CK + N N SV QA
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRH----GDSVTFACKTNFSMNGNKSVWC-QANN 136
Query: 321 REGIVEYPRC 330
G P C
Sbjct: 137 MWGPTRLPTC 146
>gi|148922949 complement component (3b/4b) receptor 1-like [Homo
sapiens]
Length = 569
Score = 65.9 bits (159), Expect = 5e-11
Identities = 62/215 (28%), Positives = 93/215 (43%), Gaps = 33/215 (15%)
Query: 113 IQYKCKPGYATADGNSSGSITCLQNG-WSAQPICIKFCDMPVFENSRAKSNGMRFKLHD- 170
+ Y+C+PGY+ SI CL+N W++ C N NGM + D
Sbjct: 61 LNYECRPGYS----GRPFSIICLKNSVWTSAK---DKCKRKSCRNPPDPVNGMAHVIKDI 113
Query: 171 ----TLDYECYDGYEISYGNTTGSIVCGEDG-WSH-FPTCYNSSEKCGPPPPISNGDTTS 224
+ Y C GY + ++ I+ G W + P C CG PP I+NGD TS
Sbjct: 114 QFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVC--DRIICGLPPTIANGDFTS 171
Query: 225 FLLKVYVPQSRVEYQC------QSYYELQGSNYVTCSN-----GEWSEP-PRCIHPCIIT 272
+ + S V Y C + +EL G + C++ G WS P P+CI P T
Sbjct: 172 ISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCT 231
Query: 273 EENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGY 307
N+ +N I + SD + + +EF C+ G+
Sbjct: 232 PPNV-ENGILV---SDNRSLFSLNEVVEFRCQPGF 262
Score = 55.8 bits (133), Expect = 5e-08
Identities = 55/204 (26%), Positives = 85/204 (41%), Gaps = 27/204 (13%)
Query: 78 WSPTVP-CLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQ 136
W P +P C R C + + +E+ Y C+PGY D S + C
Sbjct: 278 WEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY---DLRGSTYLHCTP 334
Query: 137 NG-WS-AQPIC-IKFCDMPVFENSRAKSNG-----MRFKLHDTLDYECYDGYEISYGNTT 188
G WS A P C +K CD + NG + +L +D+ C +G+++ + +
Sbjct: 335 QGDWSPAAPRCEVKSCD----DFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSAS 390
Query: 189 GSIVCG-EDGW-SHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYEL 246
++ G E W S P C S C PP NG + ++V SR+ Y C + + L
Sbjct: 391 YCVLAGMESLWNSSVPVCERKS--CETPPVPVNG-MVHVITDIHV-GSRINYSCTTGHRL 446
Query: 247 QGSNYVTC----SNGEWS-EPPRC 265
G + C + WS +PP C
Sbjct: 447 IGHSSAECILSGNTAHWSMKPPIC 470
Score = 53.9 bits (128), Expect = 2e-07
Identities = 55/210 (26%), Positives = 82/210 (39%), Gaps = 32/210 (15%)
Query: 78 WSPTVP-CLRTCSKSDIEIENG-FISESSSIYILNKEIQYKCKPG--------------- 120
W P C R I NG F S S + + Y C G
Sbjct: 146 WDNKTPVCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSI 205
Query: 121 YATADGNSSGSITCLQNGWSAQPICIKFCDMPVFENSRAKS-NGMRFKLHDTLDYECYDG 179
Y T+ + G + +G + Q I C P EN S N F L++ +++ C G
Sbjct: 206 YCTSKDDQVG----IWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPG 261
Query: 180 YEISYGNTTGSIVCGE-DGWS-HFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVE 237
+ + + C + W P+C S C PPP + + + T + P V
Sbjct: 262 FGMK---GPSHVKCQALNKWEPELPSC---SRVCQPPPDVLHAERTQRDKDNFSPGQEVF 315
Query: 238 YQCQSYYELQGSNYVTCS-NGEWS-EPPRC 265
Y C+ Y+L+GS Y+ C+ G+WS PRC
Sbjct: 316 YSCEPGYDLRGSTYLHCTPQGDWSPAAPRC 345
Score = 36.2 bits (82), Expect = 0.042
Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 23/116 (19%)
Query: 149 CDMPV---FENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSHFPTC 204
C++P F ++ F + L+YEC GY SI+C ++ W+
Sbjct: 35 CNVPEWLPFARPTNLTDDFEFPIGTYLNYECRPGYS----GRPFSIICLKNSVWT----- 85
Query: 205 YNSSEKC------GPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC 254
++ +KC PP P++ + ++K +S+++Y C Y L GS+ TC
Sbjct: 86 -SAKDKCKRKSCRNPPDPVNG---MAHVIKDIQFRSQIKYSCPKGYRLIGSSSATC 137
>gi|81295416 sushi domain containing 4 isoform b [Homo sapiens]
Length = 290
Score = 63.9 bits (154), Expect = 2e-10
Identities = 54/195 (27%), Positives = 91/195 (46%), Gaps = 23/195 (11%)
Query: 85 LRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQN-----GW 139
L+ C+ I ENGF + S ++ ++ C+ G+ CL++ GW
Sbjct: 54 LQVCADPGIP-ENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKR---LCLKHFNGTLGW 109
Query: 140 --SAQPICI-KFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSI-VCGE 195
S IC+ + C +P E+ A+ + ++ + L C++G++I Y + + +C +
Sbjct: 110 IPSDNSICVQEDCRIPQIED--AEIHNKTYRHGEKLIITCHEGFKIRYPDLHNMVSLCRD 167
Query: 196 DG-WSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRV-EYQCQSYYELQGSNYVT 253
DG W++ P C + C P SNG L+ P V Y+C ++L GS Y+
Sbjct: 168 DGTWNNLPIC----QGCLRPLASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLE 223
Query: 254 C-SNGEW-SEPPRCI 266
C N W S PPRC+
Sbjct: 224 CLQNLIWSSSPPRCL 238
>gi|168693643 decay accelerating factor for complement isoform 2
precursor [Homo sapiens]
Length = 440
Score = 61.6 bits (148), Expect = 9e-10
Identities = 68/287 (23%), Positives = 112/287 (39%), Gaps = 52/287 (18%)
Query: 1 MLLLINVILTLWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQS-------YS 53
+LL++ + +W C P D P Q PA G++ +
Sbjct: 22 LLLVLLCLPAVWGDCG-----LPPDVPNAQ--------------PALEGRTSFPEDTVIT 62
Query: 54 YYCDQNFVTPSGSYWDYIHCTQDGWSPTVP-CLRTCSK----SDIEIENGFISESSSIYI 108
Y C+++FV G I WS C R+C + ++ +I+++ +
Sbjct: 63 YKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQN--YFP 120
Query: 109 LNKEIQYKCKPGYATADGNSSGSITCLQN-GWSAQPICIKFCDMPVFENSRAKSNGM--- 164
+ ++Y+C+PGY + + S +TCLQN WS ++FC N NG
Sbjct: 121 VGTVVEYECRPGY-RREPSLSPKLTCLQNLKWST---AVEFCKKKSCPNPGEIRNGQIDV 176
Query: 165 --RFKLHDTLDYECYDGYEISYGNTTGSIVCGED-GWSH-FPTCYNSSEKCGPPPPISNG 220
T+ + C GY++ ++ ++ G WS P C C PP I NG
Sbjct: 177 PGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC--REIYCPAPPQIDNG 234
Query: 221 DTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCS----NGEWSEPP 263
Y + V Y C + + G + + C+ GEWS PP
Sbjct: 235 -IIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPP 280
Score = 35.4 bits (80), Expect = 0.071
Identities = 30/118 (25%), Positives = 50/118 (42%), Gaps = 8/118 (6%)
Query: 211 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQ-SYYELQGS-NYVTCSNG-EWSEPPR-CI 266
CG PP + N + + + Y+C+ S+ ++ G + V C G +WS+ C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 267 HPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSFQAVCREGI 324
C E N+ LK + Y G +E+ C+ GY S LS + C + +
Sbjct: 96 RSC---EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPS-LSPKLTCLQNL 149
Score = 30.8 bits (68), Expect = 1.7
Identities = 43/171 (25%), Positives = 65/171 (38%), Gaps = 13/171 (7%)
Query: 152 PVFENSRAKSNGMRFKLHDT-LDYECYDGYEISYGNTTGSIVCGEDGWSHFPTCYNSSEK 210
P N++ G DT + Y+C + + G I WS N S
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRS-- 97
Query: 211 CGPPPPISNGDTTS-FLLKVYVPQSRV-EYQCQSYYELQGS--NYVTC-SNGEWSEPPRC 265
C P +++ ++ + Y P V EY+C+ Y + S +TC N +WS
Sbjct: 98 CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST---A 154
Query: 266 IHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSF 316
+ C + N I+ G+ D+ G TI F C GY S SF
Sbjct: 155 VEFCK-KKSCPNPGEIR-NGQIDVPGGILFGATISFSCNTGYKLFGSTSSF 203
>gi|10835143 decay accelerating factor for complement isoform 1
preproprotein [Homo sapiens]
Length = 381
Score = 61.6 bits (148), Expect = 9e-10
Identities = 68/287 (23%), Positives = 112/287 (39%), Gaps = 52/287 (18%)
Query: 1 MLLLINVILTLWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQS-------YS 53
+LL++ + +W C P D P Q PA G++ +
Sbjct: 22 LLLVLLCLPAVWGDCG-----LPPDVPNAQ--------------PALEGRTSFPEDTVIT 62
Query: 54 YYCDQNFVTPSGSYWDYIHCTQDGWSPTVP-CLRTCSK----SDIEIENGFISESSSIYI 108
Y C+++FV G I WS C R+C + ++ +I+++ +
Sbjct: 63 YKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQN--YFP 120
Query: 109 LNKEIQYKCKPGYATADGNSSGSITCLQN-GWSAQPICIKFCDMPVFENSRAKSNGM--- 164
+ ++Y+C+PGY + + S +TCLQN WS ++FC N NG
Sbjct: 121 VGTVVEYECRPGY-RREPSLSPKLTCLQNLKWST---AVEFCKKKSCPNPGEIRNGQIDV 176
Query: 165 --RFKLHDTLDYECYDGYEISYGNTTGSIVCGED-GWSH-FPTCYNSSEKCGPPPPISNG 220
T+ + C GY++ ++ ++ G WS P C C PP I NG
Sbjct: 177 PGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC--REIYCPAPPQIDNG 234
Query: 221 DTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCS----NGEWSEPP 263
Y + V Y C + + G + + C+ GEWS PP
Sbjct: 235 -IIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPP 280
Score = 35.4 bits (80), Expect = 0.071
Identities = 30/118 (25%), Positives = 50/118 (42%), Gaps = 8/118 (6%)
Query: 211 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQ-SYYELQGS-NYVTCSNG-EWSEPPR-CI 266
CG PP + N + + + Y+C+ S+ ++ G + V C G +WS+ C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 267 HPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSFQAVCREGI 324
C E N+ LK + Y G +E+ C+ GY S LS + C + +
Sbjct: 96 RSC---EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPS-LSPKLTCLQNL 149
Score = 30.8 bits (68), Expect = 1.7
Identities = 43/171 (25%), Positives = 65/171 (38%), Gaps = 13/171 (7%)
Query: 152 PVFENSRAKSNGMRFKLHDT-LDYECYDGYEISYGNTTGSIVCGEDGWSHFPTCYNSSEK 210
P N++ G DT + Y+C + + G I WS N S
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRS-- 97
Query: 211 CGPPPPISNGDTTS-FLLKVYVPQSRV-EYQCQSYYELQGS--NYVTC-SNGEWSEPPRC 265
C P +++ ++ + Y P V EY+C+ Y + S +TC N +WS
Sbjct: 98 CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST---A 154
Query: 266 IHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSF 316
+ C + N I+ G+ D+ G TI F C GY S SF
Sbjct: 155 VEFCK-KKSCPNPGEIR-NGQIDVPGGILFGATISFSCNTGYKLFGSTSSF 203
>gi|4502503 complement component 4 binding protein, alpha chain
precursor [Homo sapiens]
Length = 597
Score = 60.1 bits (144), Expect = 3e-09
Identities = 77/355 (21%), Positives = 131/355 (36%), Gaps = 65/355 (18%)
Query: 6 NVILTLWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYY------CDQN 59
N + +W E C P++ HG + + G Y+Y C +
Sbjct: 221 NETIGVWRPSPPTCEKITCRKPDVSHGEMV----------SGFGPIYNYKDTIVFKCQKG 270
Query: 60 FVTPSGSYWDYIHCTQDG-WSPTVP------CLRTCSKSDIEIENGFISESSSIYILNKE 112
FV S IHC D W+P+ P C+ E +Y++
Sbjct: 271 FVLRGSSV---IHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTV 327
Query: 113 IQYKCKPGYATADGNSSGSITCLQN-GWSAQPICIKFC---------DMPVFENSRAKSN 162
++Y+C PGY + ++ C +N W+ C C ++ SR ++
Sbjct: 328 LRYRCHPGYKPTTDEPT-TVICQKNLRWTPYQGCEALCCPEPKLNNGEITQHRKSRPANH 386
Query: 163 GMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSHFPTCYNSSEKCGPPPPISNGD 221
+ F D + + C++ + S +C DG WS P + + C PP I++G
Sbjct: 387 CVYF-YGDEISFSCHE-------TSRFSAICQGDGTWS--PRTPSCGDICNFPPKIAHGH 436
Query: 222 TTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEWSEP-PRCIHPCIITEENMNKNN 280
+ + + Y+C Y L G ++CS WS P P+C C E + +
Sbjct: 437 YKQSSSYSFFKEEII-YECDKGYILVGQAKLSCSYSHWSAPAPQCKALCRKPELVNGRLS 495
Query: 281 IQLKGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSFQAVCREG----IVEYPRCE 331
+ D Y + + + C GY V+ Q++ G E P+CE
Sbjct: 496 V------DKDQYVEP-ENVTIQCDSGY----GVVGPQSITCSGNRTWYPEVPKCE 539
Score = 45.4 bits (106), Expect = 7e-05
Identities = 60/298 (20%), Positives = 115/298 (38%), Gaps = 25/298 (8%)
Query: 49 GQSYSYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVPCLRTCSKSDIEIENGFISESSSIY 107
G + Y C +V + + C DG W C+ + E+ NG + + +
Sbjct: 74 GTTLKYTCLPGYVRSHST--QTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVEIKTDLS 131
Query: 108 ILNKEIQYKCKPGYATADGNSSG-SITCLQNGWSAQ-PIC--IKFCDMPVFENSRAKSNG 163
+I++ C G+ +S + GWS P C +K P N R
Sbjct: 132 F-GSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDIRNGRHSGEE 190
Query: 164 MRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-----WSHFP-TCYNSSEKCGPPPPI 217
+ ++ Y C + + G+ SI C + W P TC + + P +
Sbjct: 191 NFYAYGFSVTYSCDPRFSL-LGHA--SISCTVENETIGVWRPSPPTCEKITCR---KPDV 244
Query: 218 SNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEWS-EPPRCIHPCIITEEN 275
S+G+ S +Y + + ++CQ + L+GS+ + C ++ +W+ PP C I +
Sbjct: 245 SHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPD 304
Query: 276 MNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSFQAVCREGI--VEYPRCE 331
+ + + + + G + + C GY T + +C++ + Y CE
Sbjct: 305 IPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPT-TVICQKNLRWTPYQGCE 361
Score = 40.8 bits (94), Expect = 0.002
Identities = 33/108 (30%), Positives = 49/108 (45%), Gaps = 14/108 (12%)
Query: 165 RFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSHFPTCYNSSEKCGPPPPISNGDTT 223
RFK TL Y C GY S+ +T ++ C DG W + C ++C P + NG
Sbjct: 70 RFKTGTTLKYTCLPGYVRSH--STQTLTCNSDGEWVYNTFCI--YKRCRHPGELRNGQVE 125
Query: 224 SFLLKVYVP-QSRVEYQCQSYYELQGSNYVTCSNGE----WSEP-PRC 265
+K + S++E+ C + L GS C + WS P P+C
Sbjct: 126 ---IKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQC 170
Score = 36.2 bits (82), Expect = 0.042
Identities = 33/128 (25%), Positives = 52/128 (40%), Gaps = 13/128 (10%)
Query: 211 CGPPPPISNGDTTSFLLKV--YVPQSRVEYQC-QSYYELQGSNYVTC-SNGEWSEPPRCI 266
CGPPP +S L + + ++Y C Y + +TC S+GEW CI
Sbjct: 50 CGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCI 109
Query: 267 HPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSFQAVCREGI-- 324
+ + +++ K+D+ + G IEF C G+ S S V G+
Sbjct: 110 YKRCRHPGELRNGQVEI--KTDLSF----GSQIEFSCSEGFFLIGSTTSRCEVQDRGVGW 163
Query: 325 -VEYPRCE 331
P+CE
Sbjct: 164 SHPLPQCE 171
>gi|153266841 apolipoprotein H precursor [Homo sapiens]
Length = 345
Score = 57.0 bits (136), Expect = 2e-08
Identities = 55/195 (28%), Positives = 82/195 (42%), Gaps = 30/195 (15%)
Query: 86 RTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPIC 145
RTC K D ++ + + Y +EI Y CKPGY + G I L W PI
Sbjct: 21 RTCPKPD-DLPFSTVVPLKTFYEPGEEITYSCKPGYVSR-GGMRKFICPLTGLW---PIN 75
Query: 146 IKFCDMPVFENSRAKSNG----MRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WS- 199
C V + NG F+ +T+ + C G+ Y N S C E+G WS
Sbjct: 76 TLKCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGF---YLNGADSAKCTEEGKWSP 132
Query: 200 HFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVP--------QSRVEYQCQSYYELQGSNY 251
P C + PPP I T L+VY P + ++C + + G++
Sbjct: 133 ELPVC---APIICPPPSI----PTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDT 185
Query: 252 VTC-SNGEWSEPPRC 265
+TC ++G W++ P C
Sbjct: 186 ITCTTHGNWTKLPEC 200
Score = 39.7 bits (91), Expect = 0.004
Identities = 43/188 (22%), Positives = 69/188 (36%), Gaps = 28/188 (14%)
Query: 69 DYIHCTQDG-WSPTVPCLRTCSKSDIEIENGFISESSSIYILNKE-IQYKCKPGYATADG 126
D I CT G W+ C +NGF++ + + K+ + C GY+ DG
Sbjct: 184 DTITCTTHGNWTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSL-DG 242
Query: 127 NSSGSITCLQNGWSAQPICIKFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGN 186
T L N WSA P C C +PV + + G R K+ + G ++S+
Sbjct: 243 PEEIECTKLGN-WSAMPSCKASCKVPV-KKATVVYQGERVKIQEKFKNGMLHGDKVSF-- 298
Query: 187 TTGSIVCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYEL 246
C N +KC D T + VP+ E+ ++++
Sbjct: 299 ----------------FCKNKEKKCSYTEDAQCIDGT-----IEVPKCFKEHSSLAFWKT 337
Query: 247 QGSNYVTC 254
S+ C
Sbjct: 338 DASDVKPC 345
>gi|32261332 seizure related 6 homolog (mouse)-like precursor [Homo
sapiens]
Length = 1024
Score = 54.3 bits (129), Expect = 1e-07
Identities = 53/194 (27%), Positives = 85/194 (43%), Gaps = 18/194 (9%)
Query: 86 RTCSKSDI-EIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQN-GWSAQP 143
R S SD+ EI+NG+ + S + + I Y+C PGY D S ++TC + WS+ P
Sbjct: 741 RNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGY---DIVGSDTLTCQWDLSWSSDP 797
Query: 144 -IC--IKFCDMP--VFENSRAKSNGMRFKLHDTLDYECYDGYEISYGN--TTGSIVCGED 196
C I +C P V ++R S+ + + T+ Y C G+ + + T S G
Sbjct: 798 PFCEKIMYCTDPGEVDHSTRLISDPVLL-VGTTIQYTCNPGFVLEGSSLLTCYSRETGTP 856
Query: 197 GW-SHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCS 255
W S P C + P + ++Y+P + + C +EL G + C
Sbjct: 857 IWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCI 916
Query: 256 NGE---WSEP-PRC 265
G+ W+ P P C
Sbjct: 917 LGQPSHWNGPLPVC 930
Score = 32.0 bits (71), Expect = 0.78
Identities = 25/80 (31%), Positives = 32/80 (40%), Gaps = 8/80 (10%)
Query: 195 EDGWSHFPTCYNSSE-KCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVT 253
+DG F Y + C P +GD T L + C YELQG+ +T
Sbjct: 376 DDGLGTFQLHYQAFMLSCNFPRRPDSGDVTVMDLH---SGGVAHFHCHLGYELQGAKMLT 432
Query: 254 CSNG---EW-SEPPRCIHPC 269
C N W S+ P C PC
Sbjct: 433 CINASKPHWSSQEPICSAPC 452
>gi|116174738 pappalysin 2 isoform 1 [Homo sapiens]
Length = 1791
Score = 50.4 bits (119), Expect = 2e-06
Identities = 59/220 (26%), Positives = 85/220 (38%), Gaps = 44/220 (20%)
Query: 44 FPAAAGQSYSYYCDQNFVTPSG----SYWDYIHCTQDG-WS-PTVPCLRTCSKSDIEIEN 97
F + G + C + V P+ S W + C +DG WS P V C C I +
Sbjct: 1477 FSCSEGTKFLKRCSISCVPPAKLQGLSPW--LTCLEDGLWSLPEVYCKLECDAPPIILNA 1534
Query: 98 GFISES--SSIYILNKEIQYKCKPGYATADG------NSSGSITCLQNGWSAQPICIK-F 148
+ + + +Y+CKPGY A+ N I CL+ G Q CI
Sbjct: 1535 NLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPVV 1594
Query: 149 CD--MPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WS-HFPTC 204
C+ PVFE +NG +LD +C + I+C ++G W+ F C
Sbjct: 1595 CEPPPPVFEGMYECTNGF------SLDSQCV--LNCNQEREKLPILCTKEGLWTQEFKLC 1646
Query: 205 YNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYY 244
N +C PPP N VEY+C+ Y
Sbjct: 1647 ENLQGECPPPPSELNS---------------VEYKCEQGY 1671
>gi|5454086 sushi-repeat-containing protein, X-linked [Homo sapiens]
Length = 464
Score = 50.4 bits (119), Expect = 2e-06
Identities = 65/277 (23%), Positives = 101/277 (36%), Gaps = 51/277 (18%)
Query: 24 CDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWSPTVP 83
C ++++G +Y ++ + Y+ A G C + + S I + WS V
Sbjct: 57 CSPIKVKYGDVYCRAPQGGYYKTALGTRCDIRCQKGYELHGSSL--LICQSNKRWSDKVI 114
Query: 84 CL-RTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQN-GWSA 141
C + C + GF + + N +Y C PGY ++TC+ N WS
Sbjct: 115 CKQKRCPTLAMPANGGFKCVDGAYF--NSRCEYYCSPGYTL---KGERTVTCMDNKAWSG 169
Query: 142 QPICIKFCDMPVFENSRAKSN-GMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDGWSH 200
+P + P + K KL + +E +G + + G T I+ G S+
Sbjct: 170 RPASCVDMEPPRIKCPSVKERIAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSN 229
Query: 201 FP--------TCYNSSEKCGPPPPISNGDTTSFLLKVYVPQ------------------- 233
FP T Y+ +E G T F +KV V +
Sbjct: 230 FPEGDHKIQYTVYDRAENKG---------TCKFRVKVRVKRCGKLNAPENGYMKCSSDGD 280
Query: 234 ---SRVEYQCQSYYELQGSNYVTC-SNGEWS-EPPRC 265
+ E+ C YELQGS C SN WS P C
Sbjct: 281 NYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTC 317
Score = 35.0 bits (79), Expect = 0.093
Identities = 39/140 (27%), Positives = 55/140 (39%), Gaps = 23/140 (16%)
Query: 143 PICIKFCDMPVFENSRAKSNGM-RFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSH 200
PI +K+ D+ RA G + L D C GYE+ + + ++C + WS
Sbjct: 59 PIKVKYGDV----YCRAPQGGYYKTALGTRCDIRCQKGYEL---HGSSLLICQSNKRWSD 111
Query: 201 FPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC-SNGEW 259
C ++C +NG + SR EY C Y L+G VTC N W
Sbjct: 112 KVIC--KQKRCPTLAMPANGGFKCVDGAYF--NSRCEYYCSPGYTLKGERTVTCMDNKAW 167
Query: 260 S---------EPPRCIHPCI 270
S EPPR P +
Sbjct: 168 SGRPASCVDMEPPRIKCPSV 187
>gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4
[Homo sapiens]
Length = 809
Score = 49.3 bits (116), Expect = 5e-06
Identities = 54/205 (26%), Positives = 81/205 (39%), Gaps = 19/205 (9%)
Query: 96 ENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQN-GWS-AQPICIKF---CD 150
E G+ + S I + Y+C+PGY S +TC + WS A P C K D
Sbjct: 537 EWGWRTASHGDLIRGTVLTYQCEPGYELL---GSDILTCQWDLSWSAAPPACQKIMTCAD 593
Query: 151 MPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGN--TTGSIVCGEDGWS-HFPTCYNS 207
N ++ F + + Y C GY + T S G WS P C
Sbjct: 594 PGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALK 653
Query: 208 SEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNG---EW-SEPP 263
E C P NG T + +S + + C +EL G +TC G +W S+PP
Sbjct: 654 YEPCLNPGVPENGYQTLYKHHYQAGES-LRFFCYEGFELIGEVTITCVPGHPSQWTSQPP 712
Query: 264 RCIHPCIITEENMNKNNIQLKGKSD 288
C + EE ++ +++ +D
Sbjct: 713 LC---KVAYEELLDNRKLEVTQTTD 734
Score = 48.5 bits (114), Expect = 8e-06
Identities = 40/146 (27%), Positives = 65/146 (44%), Gaps = 20/146 (13%)
Query: 172 LDYECYDGYEISYGNTTGSIVCGED-GWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVY 230
L Y+C GYE+ + + C D WS P C P I+NG T+
Sbjct: 554 LTYQCEPGYELLGSDI---LTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFP 610
Query: 231 VPQSRVEYQCQSYYELQGSNYVTC-----SNGEWSE-PPRC---IHPCIITEENMNKNNI 281
V S V+Y+C Y L+G+ +TC +WS+ P+C PC+ + +N
Sbjct: 611 VG-SHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCL--NPGVPENGY 667
Query: 282 QLKGKSDIKYYAKTGDTIEFMCKLGY 307
Q + K++ + G+++ F C G+
Sbjct: 668 Q----TLYKHHYQAGESLRFFCYEGF 689
Score = 42.7 bits (99), Expect = 4e-04
Identities = 45/169 (26%), Positives = 73/169 (43%), Gaps = 23/169 (13%)
Query: 49 GQSYSYYCDQNFVTPSGSYWDYIHCTQD-GWSPTVPC---LRTCSKSDIEIENGFISESS 104
G +Y C+ + D + C D WS P + TC+ EI NG + S
Sbjct: 551 GTVLTYQCEPGYELLGS---DILTCQWDLSWSAAPPACQKIMTCADPG-EIANGHRTASD 606
Query: 105 SIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-----WSAQ-PIC-IKF--CDMP-VF 154
+ + + +QY+C PGY+ + +TC WS + P C +K+ C P V
Sbjct: 607 AGFPVGSHVQYRCLPGYSL---EGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVP 663
Query: 155 ENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSHFP 202
EN ++ ++L + CY+G+E+ G T + V G W+ P
Sbjct: 664 ENGYQTLYKHHYQAGESLRFFCYEGFEL-IGEVTITCVPGHPSQWTSQP 711
Score = 37.7 bits (86), Expect = 0.014
Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 7/75 (9%)
Query: 211 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNG---EWS-EPPRCI 266
CG PP ++GD + L P + C S Y+LQG + C NG W+ E P C+
Sbjct: 176 CGFPPRPAHGDVSVTDLH---PGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 232
Query: 267 HPCIITEENMNKNNI 281
C T N I
Sbjct: 233 ASCGGTIHNATLGRI 247
Score = 32.3 bits (72), Expect = 0.60
Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 10/75 (13%)
Query: 238 YQCQSYYELQGSNYVTCS-NGEWS-EPPRC--IHPCIITEENMNKNNIQLKGKSDIKYYA 293
YQC+ YEL GS+ +TC + WS PP C I C E N + + SD +
Sbjct: 556 YQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGH----RTASDAGF-- 609
Query: 294 KTGDTIEFMCKLGYN 308
G +++ C GY+
Sbjct: 610 PVGSHVQYRCLPGYS 624
>gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [Homo
sapiens]
Length = 853
Score = 49.3 bits (116), Expect = 5e-06
Identities = 54/205 (26%), Positives = 81/205 (39%), Gaps = 19/205 (9%)
Query: 96 ENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQN-GWS-AQPICIKF---CD 150
E G+ + S I + Y+C+PGY S +TC + WS A P C K D
Sbjct: 581 EWGWRTASHGDLIRGTVLTYQCEPGYELL---GSDILTCQWDLSWSAAPPACQKIMTCAD 637
Query: 151 MPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGN--TTGSIVCGEDGWS-HFPTCYNS 207
N ++ F + + Y C GY + T S G WS P C
Sbjct: 638 PGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALK 697
Query: 208 SEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNG---EW-SEPP 263
E C P NG T + +S + + C +EL G +TC G +W S+PP
Sbjct: 698 YEPCLNPGVPENGYQTLYKHHYQAGES-LRFFCYEGFELIGEVTITCVPGHPSQWTSQPP 756
Query: 264 RCIHPCIITEENMNKNNIQLKGKSD 288
C + EE ++ +++ +D
Sbjct: 757 LC---KVAYEELLDNRKLEVTQTTD 778
Score = 48.5 bits (114), Expect = 8e-06
Identities = 40/146 (27%), Positives = 65/146 (44%), Gaps = 20/146 (13%)
Query: 172 LDYECYDGYEISYGNTTGSIVCGED-GWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVY 230
L Y+C GYE+ + + C D WS P C P I+NG T+
Sbjct: 598 LTYQCEPGYELLGSDI---LTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFP 654
Query: 231 VPQSRVEYQCQSYYELQGSNYVTC-----SNGEWSE-PPRC---IHPCIITEENMNKNNI 281
V S V+Y+C Y L+G+ +TC +WS+ P+C PC+ + +N
Sbjct: 655 VG-SHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCL--NPGVPENGY 711
Query: 282 QLKGKSDIKYYAKTGDTIEFMCKLGY 307
Q + K++ + G+++ F C G+
Sbjct: 712 Q----TLYKHHYQAGESLRFFCYEGF 733
Score = 42.7 bits (99), Expect = 4e-04
Identities = 45/169 (26%), Positives = 73/169 (43%), Gaps = 23/169 (13%)
Query: 49 GQSYSYYCDQNFVTPSGSYWDYIHCTQD-GWSPTVPC---LRTCSKSDIEIENGFISESS 104
G +Y C+ + D + C D WS P + TC+ EI NG + S
Sbjct: 595 GTVLTYQCEPGYELLGS---DILTCQWDLSWSAAPPACQKIMTCADPG-EIANGHRTASD 650
Query: 105 SIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-----WSAQ-PIC-IKF--CDMP-VF 154
+ + + +QY+C PGY+ + +TC WS + P C +K+ C P V
Sbjct: 651 AGFPVGSHVQYRCLPGYSL---EGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVP 707
Query: 155 ENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WSHFP 202
EN ++ ++L + CY+G+E+ G T + V G W+ P
Sbjct: 708 ENGYQTLYKHHYQAGESLRFFCYEGFEL-IGEVTITCVPGHPSQWTSQP 755
Score = 37.7 bits (86), Expect = 0.014
Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 7/75 (9%)
Query: 211 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNG---EWS-EPPRCI 266
CG PP ++GD + L P + C S Y+LQG + C NG W+ E P C+
Sbjct: 220 CGFPPRPAHGDVSVTDLH---PGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 276
Query: 267 HPCIITEENMNKNNI 281
C T N I
Sbjct: 277 ASCGGTIHNATLGRI 291
Score = 32.3 bits (72), Expect = 0.60
Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 10/75 (13%)
Query: 238 YQCQSYYELQGSNYVTCS-NGEWS-EPPRC--IHPCIITEENMNKNNIQLKGKSDIKYYA 293
YQC+ YEL GS+ +TC + WS PP C I C E N + + SD +
Sbjct: 600 YQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGH----RTASDAGF-- 653
Query: 294 KTGDTIEFMCKLGYN 308
G +++ C GY+
Sbjct: 654 PVGSHVQYRCLPGYS 668
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.443
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,108,500
Number of Sequences: 37866
Number of extensions: 724289
Number of successful extensions: 2266
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 1568
Number of HSP's gapped (non-prelim): 413
length of query: 331
length of database: 18,247,518
effective HSP length: 103
effective length of query: 228
effective length of database: 14,347,320
effective search space: 3271188960
effective search space used: 3271188960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.