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Search of human proteins with 117168245
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117168245 ATPase, aminophospholipid transporter-like, Class
I, type 8A, member 2 [Homo sapiens]
(1188 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117168245 ATPase, aminophospholipid transporter-like, Class I... 2381 0.0
gi|17978471 ATPase, aminophospholipid transporter (APLT), class ... 1613 0.0
gi|157649069 ATPase, aminophospholipid transporter (APLT), class... 1597 0.0
gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo s... 848 0.0
gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens] 835 0.0
gi|50083277 ATPase class I type 8B member 4 [Homo sapiens] 831 0.0
gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens] 693 0.0
gi|62632750 ATPase, class VI, type 11B [Homo sapiens] 678 0.0
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens] 670 0.0
gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens] 667 0.0
gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens] 622 e-178
gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens] 622 e-178
gi|65301139 ATPase, class II, type 9A [Homo sapiens] 439 e-122
gi|41327760 ATPase, class II, type 9B [Homo sapiens] 423 e-118
gi|149944474 ATPase, class V, type 10B [Homo sapiens] 410 e-114
gi|222352161 ATPase, class V, type 10D [Homo sapiens] 400 e-111
gi|14424433 ATPase, class V, type 10A [Homo sapiens] 393 e-109
gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo s... 266 9e-71
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 115 3e-25
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 115 3e-25
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 100 6e-21
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 92 2e-18
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 92 2e-18
gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap... 91 7e-18
gi|66932949 ATPase type 13A4 [Homo sapiens] 87 7e-17
gi|148839292 ATPase type 13A3 [Homo sapiens] 77 7e-14
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 74 1e-12
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 74 1e-12
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi... 69 2e-11
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi... 69 2e-11
>gi|117168245 ATPase, aminophospholipid transporter-like, Class I,
type 8A, member 2 [Homo sapiens]
Length = 1188
Score = 2381 bits (6171), Expect = 0.0
Identities = 1188/1188 (100%), Positives = 1188/1188 (100%)
Query: 1 MLNGAGLDKALKMSLPRRSRIRSSVGPVRSSLGYKKAEDEMSRATSVGDQLEAPARTIYL 60
MLNGAGLDKALKMSLPRRSRIRSSVGPVRSSLGYKKAEDEMSRATSVGDQLEAPARTIYL
Sbjct: 1 MLNGAGLDKALKMSLPRRSRIRSSVGPVRSSLGYKKAEDEMSRATSVGDQLEAPARTIYL 60
Query: 61 NQPHLNKFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTT 120
NQPHLNKFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTT
Sbjct: 61 NQPHLNKFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTT 120
Query: 121 LVPLIIILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVN 180
LVPLIIILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVN
Sbjct: 121 LVPLIIILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVN 180
Query: 181 GQYLPADVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGTIEC 240
GQYLPADVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGTIEC
Sbjct: 181 GQYLPADVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGTIEC 240
Query: 241 EGPNRHLYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNST 300
EGPNRHLYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNST
Sbjct: 241 EGPNRHLYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNST 300
Query: 301 KAPLKRSNVEKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSDNFG 360
KAPLKRSNVEKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSDNFG
Sbjct: 301 KAPLKRSNVEKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSDNFG 360
Query: 361 YNLLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELG 420
YNLLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELG
Sbjct: 361 YNLLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELG 420
Query: 421 QVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSCDFDD 480
QVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSCDFDD
Sbjct: 421 QVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSCDFDD 480
Query: 481 PRLLKNIEDRHPTAPCIQEFLTLLAVCHTVVPEKDGDNIIYQASSPDEAALVKGAKKLGF 540
PRLLKNIEDRHPTAPCIQEFLTLLAVCHTVVPEKDGDNIIYQASSPDEAALVKGAKKLGF
Sbjct: 481 PRLLKNIEDRHPTAPCIQEFLTLLAVCHTVVPEKDGDNIIYQASSPDEAALVKGAKKLGF 540
Query: 541 VFTARTPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFE 600
VFTARTPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFE
Sbjct: 541 VFTARTPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFE 600
Query: 601 RLSKDSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRL 660
RLSKDSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRL
Sbjct: 601 RLSKDSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRL 660
Query: 661 EECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCR 720
EECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCR
Sbjct: 661 EECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCR 720
Query: 721 LVSQNMALILLKEDSLDATRAAITQHCTDLGNLLGKENDVALIIDGHTLKYALSFEVRRS 780
LVSQNMALILLKEDSLDATRAAITQHCTDLGNLLGKENDVALIIDGHTLKYALSFEVRRS
Sbjct: 721 LVSQNMALILLKEDSLDATRAAITQHCTDLGNLLGKENDVALIIDGHTLKYALSFEVRRS 780
Query: 781 FLDLALSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISG 840
FLDLALSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISG
Sbjct: 781 FLDLALSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISG 840
Query: 841 NEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVN 900
NEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVN
Sbjct: 841 NEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVN 900
Query: 901 GFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKV 960
GFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKV
Sbjct: 901 GFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKV 960
Query: 961 FWGHCINALVHSLILFWFPMKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCLKAGLET 1020
FWGHCINALVHSLILFWFPMKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCLKAGLET
Sbjct: 961 FWGHCINALVHSLILFWFPMKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCLKAGLET 1020
Query: 1021 TAWTKFSHLAVWGSMLTWLVFFGIYSTIWPTIPIAPDMRGQATMVLSSAHFWLGLFLVPT 1080
TAWTKFSHLAVWGSMLTWLVFFGIYSTIWPTIPIAPDMRGQATMVLSSAHFWLGLFLVPT
Sbjct: 1021 TAWTKFSHLAVWGSMLTWLVFFGIYSTIWPTIPIAPDMRGQATMVLSSAHFWLGLFLVPT 1080
Query: 1081 ACLIEDVAWRAAKHTCKKTLLEEVQELETKSRVLGKAVLRDSNGKRLNERDRLIKRLGRK 1140
ACLIEDVAWRAAKHTCKKTLLEEVQELETKSRVLGKAVLRDSNGKRLNERDRLIKRLGRK
Sbjct: 1081 ACLIEDVAWRAAKHTCKKTLLEEVQELETKSRVLGKAVLRDSNGKRLNERDRLIKRLGRK 1140
Query: 1141 TPPTLFRGSSLQQGVPHGYAFSQEEHGAVSQEEVIRAYDTTKKKSRKK 1188
TPPTLFRGSSLQQGVPHGYAFSQEEHGAVSQEEVIRAYDTTKKKSRKK
Sbjct: 1141 TPPTLFRGSSLQQGVPHGYAFSQEEHGAVSQEEVIRAYDTTKKKSRKK 1188
>gi|17978471 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform a [Homo sapiens]
Length = 1164
Score = 1613 bits (4177), Expect = 0.0
Identities = 789/1165 (67%), Positives = 953/1165 (81%), Gaps = 9/1165 (0%)
Query: 21 IRSSVGPVRSSL-GYKKAEDEMSRATSVGDQLEAPARTIYLNQPHLNKFRDNQISTAKYS 79
+R +V +RS GY+K +D +S TS+ DQ E RTI++NQP L KF +N +STAKY+
Sbjct: 4 MRRTVSEIRSRAEGYEKTDD-VSEKTSLADQEEV--RTIFINQPQLTKFCNNHVSTAKYN 60
Query: 80 VLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLIIILTIAGIKEIVED 139
++TFLPRFLY Q RRAAN+FFLFIALLQQIPDVSPTGRYTTLVPL+ IL +A IKEI+ED
Sbjct: 61 IITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIED 120
Query: 140 FKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAM 199
KRHKADNAVNKK+T VLRNG W + W++VAVG+IVKV NG++LPAD++ LSSSEPQAM
Sbjct: 121 IKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEHLPADLISLSSSEPQAM 180
Query: 200 CYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNLNLDGK 259
CY+ET+NLDGETNLKIRQGL T+D++ + LM++SG IECE PNRHLYDF GN+ LDG
Sbjct: 181 CYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGH 240
Query: 260 SLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAPLKRSNVEKVTNVQILV 319
V LG DQILLRG QLRNTQWV GIVVYTGHDTKLMQNST PLK SNVE++TNVQIL+
Sbjct: 241 GTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILI 300
Query: 320 LFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSDNFGYNLLTFIILYNNLIPISLL 379
LF IL+ M+LV S G+ WNR H K+WY+ + NFG N LTFIIL+NNLIPISLL
Sbjct: 301 LFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLL 360
Query: 380 VTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMN 439
VTLEVVK+TQA FINWD DM+Y DT AMARTSNLNEELGQVKY+FSDKTGTLTCN+M
Sbjct: 361 VTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQ 420
Query: 440 FKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSCDFDDPRLLKNIEDRHPTAPCIQE 499
FKKC+IAGV YGH PE S D + D F D LL+N+++ HPTAP I E
Sbjct: 421 FKKCTIAGVAYGHVPEPEDYGCSPDEWQNSQ-FGDEKTFSDSSLLENLQNNHPTAPIICE 479
Query: 500 FLTLLAVCHTVVPEKDGDNIIYQASSPDEAALVKGAKKLGFVFTARTPFSVIIEAMGQEQ 559
FLT++AVCHT VPE++GD IIYQA+SPDE ALV+ AK+L FVFT RTP SVII+++GQE+
Sbjct: 480 FLTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEE 539
Query: 560 TFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFERLSKDSKYMEETLCHLEYF 619
+ +LNVLEF+S RKRMSVIVRTPSG+LRLYCKGAD VI++RL++ SKY E TL HLE F
Sbjct: 540 RYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQF 599
Query: 620 ATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAI 679
ATEGLRTLC A A++SE++++EW VYQ AST +++R +LEE YE+IEKNL LLGATAI
Sbjct: 600 ATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAI 659
Query: 680 EDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDAT 739
ED+LQ VPETI TL+KA+IKIW+LTGDKQETAINIG+SC+L+ +NM +I++ E SLD T
Sbjct: 660 EDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGT 719
Query: 740 RAAITQHCTDLGNLLGKENDVALIIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPL 799
R +++HCT LG+ L KEND ALIIDG TLKYAL+F VR+ FLDLALSCKAVICCRVSPL
Sbjct: 720 RETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPL 779
Query: 800 QKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFSY 859
QKSE+V++VKK+VK +TLAIGDGANDV MIQTAHVGVGISGNEG+QA N+SDY+IAQF Y
Sbjct: 780 QKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKY 839
Query: 860 LEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNVI 919
L+ LL++HGAW+YNRV+KCILYCFYKN+VLYIIE+WFAFVNGFSGQILFERWCIGLYNV+
Sbjct: 840 LKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVM 899
Query: 920 FTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKVFWGHCINALVHSLILFWFP 979
FTA+PP TLGIFERSC +E+ML++P+LYK +QN FNTKVFW HC+N L HS+ILFWFP
Sbjct: 900 FTAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFP 959
Query: 980 MKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCLKAGLETTAWTKFSHLAVWGSMLTWL 1039
+KAL++ T +G +DYL +GN VYT+VV+TVCLKAGLET+ WT FSH+A+WGS+ W+
Sbjct: 960 LKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWV 1019
Query: 1040 VFFGIYSTIWPTIPIAPDMRGQATMVLSSAHFWLGLFLVPTACLIEDVAWRAAKHTCKKT 1099
VFFGIYS++WP IP+APDM G+A M+ SS FW+GL +P A L+ DV ++ K T KT
Sbjct: 1020 VFFGIYSSLWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKT 1079
Query: 1100 LLEEVQELETKSRVLGKAVLRDSNGKRLNERDRLIKRLGRKTPPTLFRGSSLQQGVPHGY 1159
L++EVQELE KS+ G VL GK L ER +L+K + +K L+R SLQQ + HGY
Sbjct: 1080 LVDEVQELEAKSQDPGAVVL----GKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGY 1135
Query: 1160 AFSQEEHGAVSQEEVIRAYDTTKKK 1184
AFSQ+E+G VSQ EVIRAYDTTK++
Sbjct: 1136 AFSQDENGIVSQSEVIRAYDTTKQR 1160
>gi|157649069 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform b [Homo sapiens]
Length = 1149
Score = 1597 bits (4136), Expect = 0.0
Identities = 782/1165 (67%), Positives = 945/1165 (81%), Gaps = 24/1165 (2%)
Query: 21 IRSSVGPVRSSL-GYKKAEDEMSRATSVGDQLEAPARTIYLNQPHLNKFRDNQISTAKYS 79
+R +V +RS GY+K +D +S TS+ DQ E RTI++NQP L KF +N +STAKY+
Sbjct: 4 MRRTVSEIRSRAEGYEKTDD-VSEKTSLADQEEV--RTIFINQPQLTKFCNNHVSTAKYN 60
Query: 80 VLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLIIILTIAGIKEIVED 139
++TFLPRFLY Q RRAAN+FFLFIALLQQIPDVSPTGRYTTLVPL+ IL +A IKEI+ED
Sbjct: 61 IITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIED 120
Query: 140 FKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAM 199
KRHKADNAVNKK+T VLRNG W + W++V VGDIV + +Y+PAD VLLSSSEPQAM
Sbjct: 121 IKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIPADTVLLSSSEPQAM 180
Query: 200 CYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNLNLDGK 259
CY+ET+NLDGETNLKIRQGL T+D++ + LM++SG IECE PNRHLYDF GN+ LDG
Sbjct: 181 CYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGH 240
Query: 260 SLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAPLKRSNVEKVTNVQILV 319
V LG DQILLRG QLRNTQWV GIVVYTGHDTKLMQNST PLK SNVE++TNVQIL+
Sbjct: 241 GTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILI 300
Query: 320 LFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSDNFGYNLLTFIILYNNLIPISLL 379
LF IL+ M+LV S G+ WNR H K+WY+ + NFG N LTFIIL+NNLIPISLL
Sbjct: 301 LFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLL 360
Query: 380 VTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMN 439
VTLEVVK+TQA FINWD DM+Y DT AMARTSNLNEELGQVKY+FSDKTGTLTCN+M
Sbjct: 361 VTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQ 420
Query: 440 FKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSCDFDDPRLLKNIEDRHPTAPCIQE 499
FKKC+IAGV YG + E + F D LL+N+++ HPTAP I E
Sbjct: 421 FKKCTIAGVAYGQNSQFGDEKT----------------FSDSSLLENLQNNHPTAPIICE 464
Query: 500 FLTLLAVCHTVVPEKDGDNIIYQASSPDEAALVKGAKKLGFVFTARTPFSVIIEAMGQEQ 559
FLT++AVCHT VPE++GD IIYQA+SPDE ALV+ AK+L FVFT RTP SVII+++GQE+
Sbjct: 465 FLTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEE 524
Query: 560 TFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFERLSKDSKYMEETLCHLEYF 619
+ +LNVLEF+S RKRMSVIVRTPSG+LRLYCKGAD VI++RL++ SKY E TL HLE F
Sbjct: 525 RYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQF 584
Query: 620 ATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAI 679
ATEGLRTLC A A++SE++++EW VYQ AST +++R +LEE YE+IEKNL LLGATAI
Sbjct: 585 ATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAI 644
Query: 680 EDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDAT 739
ED+LQ VPETI TL+KA+IKIW+LTGDKQETAINIG+SC+L+ +NM +I++ E SLD T
Sbjct: 645 EDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGT 704
Query: 740 RAAITQHCTDLGNLLGKENDVALIIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPL 799
R +++HCT LG+ L KEND ALIIDG TLKYAL+F VR+ FLDLALSCKAVICCRVSPL
Sbjct: 705 RETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPL 764
Query: 800 QKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFSY 859
QKSE+V++VKK+VK +TLAIGDGANDV MIQTAHVGVGISGNEG+QA N+SDY+IAQF Y
Sbjct: 765 QKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKY 824
Query: 860 LEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNVI 919
L+ LL++HGAW+YNRV+KCILYCFYKN+VLYIIE+WFAFVNGFSGQILFERWCIGLYNV+
Sbjct: 825 LKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVM 884
Query: 920 FTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKVFWGHCINALVHSLILFWFP 979
FTA+PP TLGIFERSC +E+ML++P+LYK +QN FNTKVFW HC+N L HS+ILFWFP
Sbjct: 885 FTAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFP 944
Query: 980 MKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCLKAGLETTAWTKFSHLAVWGSMLTWL 1039
+KAL++ T +G +DYL +GN VYT+VV+TVCLKAGLET+ WT FSH+A+WGS+ W+
Sbjct: 945 LKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWV 1004
Query: 1040 VFFGIYSTIWPTIPIAPDMRGQATMVLSSAHFWLGLFLVPTACLIEDVAWRAAKHTCKKT 1099
VFFGIYS++WP IP+APDM G+A M+ SS FW+GL +P A L+ DV ++ K T KT
Sbjct: 1005 VFFGIYSSLWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKT 1064
Query: 1100 LLEEVQELETKSRVLGKAVLRDSNGKRLNERDRLIKRLGRKTPPTLFRGSSLQQGVPHGY 1159
L++EVQELE KS+ G VL GK L ER +L+K + +K L+R SLQQ + HGY
Sbjct: 1065 LVDEVQELEAKSQDPGAVVL----GKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGY 1120
Query: 1160 AFSQEEHGAVSQEEVIRAYDTTKKK 1184
AFSQ+E+G VSQ EVIRAYDTTK++
Sbjct: 1121 AFSQDENGIVSQSEVIRAYDTTKQR 1145
>gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo
sapiens]
Length = 1223
Score = 848 bits (2191), Expect = 0.0
Identities = 466/1138 (40%), Positives = 677/1138 (59%), Gaps = 69/1138 (6%)
Query: 67 KFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLII 126
++ N I T+KY++LTFLP L+EQ + AN +FLF+ +LQ IP +S +TT+VPL++
Sbjct: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
Query: 127 ILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPA 186
+LTI +K+ +D+ RHK+DN VN +++ VL NG+ W V VGDI+K+ N Q++ A
Sbjct: 121 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 180
Query: 187 DVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRH 246
D++LLSSSEP +CY+ETA LDGETN+K+RQ + T+++ L K G + CE PN
Sbjct: 181 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 240
Query: 247 LYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAPLKR 306
L F+G L ++ L +LLRG LRNT+W FG+V++ G DTKLMQNS + KR
Sbjct: 241 LDKFSGTLYWK-ENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKR 299
Query: 307 SNVEKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSDNFGYN---- 362
++++++ N +L +FG L+ M ++ + G W G + D D+ ++
Sbjct: 300 TSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGFLS 359
Query: 363 LLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELGQV 422
++II+ N ++PISL V++EV++ + FINWD M+ + TPA ART+ LNEELGQV
Sbjct: 360 FWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQV 419
Query: 423 KYLFSDKTGTLTCNIMNFKKCSIAGVTYG-------HFPELAREPSSDDFCRMPPPCSDS 475
+Y+FSDKTGTLT NIM F KCSI G +YG H EL P DF P
Sbjct: 420 EYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDFS-FNPLADKK 478
Query: 476 CDFDDPRLLKNIEDRHPTAPCIQEFLTLLAVCHTVVPE-KDGDNIIYQASSPDEAALVKG 534
F DP LL+ ++ P EF LL++CHTV+ E K+ + Y+A SPDE ALV
Sbjct: 479 FLFWDPSLLEAVKIGDPHT---HEFFRLLSLCHTVMSEEKNEGELYYKAQSPDEGALVTA 535
Query: 535 AKKLGFVFTARTPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGA 594
A+ GFVF +RTP ++ + MG T+ +L +L+F++ RKRMSVIVR P G++RLYCKGA
Sbjct: 536 ARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFNNIRKRMSVIVRNPEGKIRLYCKGA 595
Query: 595 DNVIFERLSKDSK-YMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASTIL 653
D ++ +RL ++ + T+ HL +A EGLRTL +AY DL E YEEW + +AS
Sbjct: 596 DTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKDLDEEYYEEWAERRLQASLAQ 655
Query: 654 KDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAI 713
R RL YE +E N++LLGATAIED+LQ GVPETIA L A IKIWVLTGDKQETA+
Sbjct: 656 DSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAV 715
Query: 714 NIGYSCRLVSQNMA--------LILLKEDSLDATRAAITQHCTDLGN------------- 752
NIGYSC++++ +M +L + L R + +GN
Sbjct: 716 NIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMDSSRSVGNGFTYQDKLSSSKL 775
Query: 753 ---LLGKENDVALIIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPLQKSEIVDVVK 809
L + AL+I+GH+L +AL ++ FL+ A +CKAVICCRV+PLQK+++V++VK
Sbjct: 776 TSVLEAVAGEYALVINGHSLAHALEADMELEFLETACACKAVICCRVTPLQKAQVVELVK 835
Query: 810 KRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGA 869
K KA+TLAIGDGANDV MI+TAH+GVGISG EG+QA SDY+ +QF +L++LLLVHG
Sbjct: 836 KYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGR 895
Query: 870 WSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNVIFTALPPFTLG 929
WSY R+ K + Y FYKN ++ WF F GFS Q +++++ I LYN+++T+LP +G
Sbjct: 896 WSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMG 955
Query: 930 IFERSCTQESMLRFPQLYKITQNGEGFNTKVFWGHCINALVHSLILFWFPMKALEHDTVL 989
+F++ ++ + +P+LY+ Q FN + F+ + S+++F+ P T
Sbjct: 956 VFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFADATRD 1015
Query: 990 TSGHATDYLFVGNIVYTYVVVTVCLKAGLETTAWTKFSHLAVWGSMLTWL-VFFGIYST- 1047
DY V T +V+ V ++ GL+T WT +H +WGS+ + + F ++S
Sbjct: 1016 DGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNG 1075
Query: 1048 IWPTIPIAPDMRGQATMVLSSAHFWLGLFLVPTACLIEDVAWRAAKHTCKKTLLEEVQEL 1107
++ P G A L+ WL + L C++ VA+R + K L + V+
Sbjct: 1076 LFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVRYT 1135
Query: 1108 ETKSRVLGKAVLRDSNGKRLNERDRLIKRLGRKTPPTLFRGSSLQQGVPHGYAFSQEE 1165
+ K+ + R ++R+GR T R S GYAFS +E
Sbjct: 1136 QLVR-------------KKQKAQHRCMRRVGR----TGSRRS--------GYAFSHQE 1168
>gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]
Length = 1251
Score = 835 bits (2156), Expect = 0.0
Identities = 468/1151 (40%), Positives = 685/1151 (59%), Gaps = 75/1151 (6%)
Query: 23 SSVGPVRSSLGYKKAEDEMSRATSVGDQLEAPARTIYLNQPHL----------NKFRDNQ 72
S+V P ++ + + E+ Q++A R Y QPH +K+ +N
Sbjct: 38 SAVEPEQNRVNREAEENREPFRKECTWQVKANDRK-YHEQPHFMNTKFLCIKESKYANNA 96
Query: 73 ISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLIIILTIAG 132
I T KY+ TF+P L+EQ +RAAN +FL + +LQ +P +S YTTLVPL+++L +
Sbjct: 97 IKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLVVLGVTA 156
Query: 133 IKEIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLS 192
IK++V+D RHK D +N + V+++G + WKE+ VGD++++ ++PAD++LLS
Sbjct: 157 IKDLVDDVARHKMDKEINNRTCEVIKDGRFKVAKWKEIQVGDVIRLKKNDFVPADILLLS 216
Query: 193 SSEPQAMCYVETANLDGETNLKIRQGLSHTAD-MQTREVLMKLSGTIECEGPNRHLYDFT 251
SSEP ++CYVETA LDGETNLK + L T +Q + L G IECE PN L FT
Sbjct: 217 SSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPNNRLDKFT 276
Query: 252 GNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAPLKRSNVEK 311
G L S L D+ILLRG +RNT + G+V++ G DTK+M+NS K KR+ ++
Sbjct: 277 GTLFWRNTSF-PLDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGKTRFKRTKIDY 335
Query: 312 VTNVQILVLFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSDNFGYNLLT--FIIL 369
+ N + +F +L++++ + G YW G +WY+ + + ++ L+ +II+
Sbjct: 336 LMNYMVYTIFVVLILLSAGLAIGHAYWEAQVGNSSWYLYDGEDDTPSYRGFLIFWGYIIV 395
Query: 370 YNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELGQVKYLFSDK 429
N ++PISL V++EV++ Q+ FINWD MYY DTPA ART+ LNE+LGQ+ Y+FSDK
Sbjct: 396 LNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDK 455
Query: 430 TGTLTCNIMNFKKCSIAGVTYGHFPELAREPSSD----DFCRMPPPCSDSCDFDDPRLLK 485
TGTLT NIM FKKC I G YG + ++ + DF F D L++
Sbjct: 456 TGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFS-WNTYADGKLAFYDHYLIE 514
Query: 486 NIEDRHPTAPCIQEFLTLLAVCHTVVPEKDGDNIIYQASSPDEAALVKGAKKLGFVFTAR 545
I+ P +++F LLAVCHTV+ ++ + YQA+SPDE ALV A+ GF F AR
Sbjct: 515 QIQSGKE--PEVRQFFFLLAVCHTVMVDRTDGQLNYQAASPDEGALVNAARNFGFAFLAR 572
Query: 546 TPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFERLSKD 605
T ++ I +G E+T+ +L +L+F+SDRKRMS+IVRTP G ++LYCKGAD VI+ERL +
Sbjct: 573 TQNTITISELGTERTYNVLAILDFNSDRKRMSIIVRTPEGNIKLYCKGADTVIYERLHRM 632
Query: 606 SKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYE 665
+ +ET L+ FA E LRTLC+ Y ++ E E+ EW K + AS +R + L++ YE
Sbjct: 633 NPTKQETQDALDIFANETLRTLCLCYKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYE 692
Query: 666 IIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQN 725
IEK+L+LLGATAIED+LQ GVPETI+ L KA+IKIWVLTGDK+ETA NIG++C L++++
Sbjct: 693 EIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFACELLTED 752
Query: 726 MALILLKEDSLDATRAAITQHCTDLGNLLGK------------ENDVALIIDGH------ 767
+ + +++ A ++ + G + K + ALII G
Sbjct: 753 TTICY--GEDINSLLHARMENQRNRGGVYAKFAPPVQESFFPPGGNRALIITGSWLNEIL 810
Query: 768 -----------TLKYALSFEVRR------------------SFLDLALSCKAVICCRVSP 798
LK+ + E RR +F+DLA C AVICCRV+P
Sbjct: 811 LEKKTKRNKILKLKFPRTEEERRMRTQSKRRLEAKKEQRQKNFVDLACECSAVICCRVTP 870
Query: 799 LQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFS 858
QK+ +VD+VK+ KAITLAIGDGANDV MI+TAH+GVGISG EGMQA +SDY+ AQF
Sbjct: 871 KQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFR 930
Query: 859 YLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNV 918
YL++LLLVHG WSY R+ K + Y FYKN ++ W++F NG+S Q +E W I LYNV
Sbjct: 931 YLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNV 990
Query: 919 IFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKVFWGHCINALVHSLILFWF 978
++T+LP +G+ ++ + + LRFP LY + Q FN K F+ ++ ++ S+ILF+
Sbjct: 991 LYTSLPVLLMGLLDQDVSDKLSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFI 1050
Query: 979 PMKALEHDTVLTSGHA-TDYLFVGNIVYTYVVVTVCLKAGLETTAWTKFSHLAVWGSMLT 1037
P+ A TV G A +DY + + +V+TV + GL+T+ WT + +++GS+
Sbjct: 1051 PLGAY-LQTVGQDGEAPSDYQSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIAL 1109
Query: 1038 WL-VFFGIYST-IWPTIPIAPDMRGQATMVLSSAHFWLGLFLVPTACLIEDVAWRAAKHT 1095
+ + F +S I P A G A+ L + WL + L CL+ VA R T
Sbjct: 1110 YFGIMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMT 1169
Query: 1096 CKKTLLEEVQE 1106
+ +++Q+
Sbjct: 1170 IWPSESDKIQK 1180
>gi|50083277 ATPase class I type 8B member 4 [Homo sapiens]
Length = 1192
Score = 831 bits (2147), Expect = 0.0
Identities = 453/1091 (41%), Positives = 675/1091 (61%), Gaps = 51/1091 (4%)
Query: 67 KFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLII 126
++ DN+I T+KY++LTFLP L+EQ +R ANA+FL + +LQ IP++S +TT+VPL++
Sbjct: 27 QYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVL 86
Query: 127 ILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPA 186
++T+ +K+ +D+ RHK+DN VN +++ VL N W V VGDI+K+ N Q++ A
Sbjct: 87 VITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAA 146
Query: 187 DVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADMQTR-EVLMKLSGTIECEGPNR 245
D++LLSSSEP +CYVETA LDGETNLK+R LS T+++ L G + CE PN
Sbjct: 147 DLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNN 206
Query: 246 HLYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAPLK 305
L F G L+ S +L ++I+LRG LRNT W FG+V++ G DTKLMQNS K K
Sbjct: 207 KLDKFMGILSWK-DSKHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGKTKFK 265
Query: 306 RSNVEKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEK-----NWYIKKMDTTSDNFG 360
R++++++ N +L +FG L+ + ++ + G W G++ W + + F
Sbjct: 266 RTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQTGDQFRTFLFWNEGEKSSVFSGF- 324
Query: 361 YNLLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELG 420
++II+ N ++PISL V++EV++ + FINWD MYY PA+ART+ LNEELG
Sbjct: 325 LTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVARTTTLNEELG 384
Query: 421 QVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGHF-------PELAREPSSDDFCRMPPPCS 473
Q++Y+FSDKTGTLT NIM FK+CSI G YG E+ +E DF +
Sbjct: 385 QIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDF-SVKSQAD 443
Query: 474 DSCDFDDPRLLKNIEDRHPTAPCIQEFLTLLAVCHTVVPEKD-GDNIIYQASSPDEAALV 532
F D L+++I+ P + EFL LLA+CHTV+ E++ +IYQ SPDE ALV
Sbjct: 444 REFQFFDHHLMESIKMGDPK---VHEFLRLLALCHTVMSEENSAGELIYQVQSPDEGALV 500
Query: 533 KGAKKLGFVFTARTPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCK 592
A+ GF+F +RTP ++ IE +G T+ +L L+F++ RKRMSVIVR P G+++LY K
Sbjct: 501 TAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRNPEGQIKLYSK 560
Query: 593 GADNVIFERLSKDSK-YMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEAST 651
GAD ++FE+L ++ + T HL FA EGLRTL +AY DL + ++EW K+ ++A+
Sbjct: 561 GADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRDLDDKYFKEWHKMLEDANA 620
Query: 652 ILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQET 711
++R +R+ YE IE++L+LLGATA+ED+LQ GV ET+ +L A IKIWVLTGDKQET
Sbjct: 621 ATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIKIWVLTGDKQET 680
Query: 712 AINIGYSCRLVSQNMALILL----------------KEDSLDATRAAITQHCT------- 748
AINIGY+C +++ +M + + K++ R H
Sbjct: 681 AINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFGQNRNFSNGHVVCEKKQQL 740
Query: 749 DLGNLLGK--ENDVALIIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPLQKSEIVD 806
+L +++ + D ALII+GH+L +AL +V+ L+LA CK VICCRV+PLQK+++V+
Sbjct: 741 ELDSIVEETITGDYALIINGHSLAHALESDVKNDLLELACMCKTVICCRVTPLQKAQVVE 800
Query: 807 VVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFSYLEKLLLV 866
+VKK A+TLAIGDGANDV MI++AH+GVGISG EG+QA SDY+ AQF YL++LLLV
Sbjct: 801 LVKKYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLV 860
Query: 867 HGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNVIFTALPPF 926
HG WSY R+ K + Y FYKN ++ WF F GFS Q ++++W I L+N+++T+LP
Sbjct: 861 HGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVL 920
Query: 927 TLGIFERSCTQESMLRFPQLYKITQNGEGFNTKVFWGHCINALVHSLILFWFPMKALEHD 986
+GIF++ + ++ + PQLYK Q FN + F+ ++ + SL+LF+ P A +
Sbjct: 921 AMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAFYNV 980
Query: 987 TVLTSGHATDYLFVGNIVYTYVVVTVCLKAGLETTAWTKFSHLAVWGSMLTWL-VFFGIY 1045
H DY + T +V+ V ++ L+T+ WT +H+ +WGS+ + + F ++
Sbjct: 981 AGEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTMH 1040
Query: 1046 ST-IWPTIPIAPDMRGQATMVLSSAHFWLGLFLVPTACLIEDVAWRAAKHTCKKTLLEEV 1104
S I+ P G A L+ WL + L A ++ VA+R K TL +++
Sbjct: 1041 SNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASVMPVVAFRFLKVDLYPTLSDQI 1100
Query: 1105 ---QELETKSR 1112
Q+ + K+R
Sbjct: 1101 RRWQKAQKKAR 1111
>gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]
Length = 1300
Score = 693 bits (1788), Expect = 0.0
Identities = 410/1055 (38%), Positives = 616/1055 (58%), Gaps = 101/1055 (9%)
Query: 67 KFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLII 126
K++ N I TAKY+ +FLP LYEQ R +N FFL I +LQ IPD+S ++ P++
Sbjct: 132 KYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTPMVC 191
Query: 127 ILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPA 186
+L I +++V+D RHK+D A+N + +L + W+++ VGD+V + +PA
Sbjct: 192 LLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDVVCLRKDNIVPA 251
Query: 187 DVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHT-ADMQTREVLMKLSGTIECEGPNR 245
D++LL+S+EP ++CYVET ++DGETNLK RQ L T ++ T + + GT+ CE PN
Sbjct: 252 DMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEAPNS 311
Query: 246 HLYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAPLK 305
++ F G L + K +L +LLRG ++RNT +G+V+Y G DTK+M+N K LK
Sbjct: 312 RMHHFVGCLEWNDKKY-SLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCGKIHLK 370
Query: 306 RSNVEKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTS---DNFGYN 362
R+ ++ + N ++V+F ++++ LV + G + + + ++Y+ + +S ++F +
Sbjct: 371 RTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAAESF-FV 429
Query: 363 LLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELGQV 422
+F+IL + IP+S+ + E + ++FI+WD MYY D PA AR+++LN+ LGQV
Sbjct: 430 FWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLGQV 489
Query: 423 KYLFSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSCDFDDPR 482
+Y+FSDKTGTLT NI+ F KC I+G YG E P + + F +
Sbjct: 490 EYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYL-WNKFADGKLLFHNAA 548
Query: 483 LLKNIEDRHPTAPCIQEFLTLLAVCHTVV----PEKDGDNIIYQASSPDEAALVKGAKKL 538
LL + A ++EF LLA+CHTV+ P + D ++YQA+SPDE ALV A+
Sbjct: 549 LLHLVRTNGDEA--VREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALVTAARNF 606
Query: 539 GFVFTARTPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVI 598
G+VF +RT +V I +G+E+ + +L +++F+S RKRMSV+VR P G + LY KGAD VI
Sbjct: 607 GYVFLSRTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVRKPEGAICLYTKGADTVI 666
Query: 599 FERLSKDSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQ 658
FERL + T L FA E LRTLC+AY +++E+ YE+W + +QEAS +L++RAQ
Sbjct: 667 FERLHRRGAMEFATEEALAAFAQETLRTLCLAYREVAEDIYEDWQQRHQEASLLLQNRAQ 726
Query: 659 RLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYS 718
L++ LLGATAIEDRLQ GVPETI L K+ IKIWVLTGDKQETA+NIG++
Sbjct: 727 ALQQ----------LLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETAVNIGFA 776
Query: 719 CRLVSQNMALILLKEDSLDATRAAITQHCTDLGNLLGKEN----DVALIIDGHTL-KYAL 773
C L+S+NM ++ KE S + + + NLL +E+ +AL+I+G L K +
Sbjct: 777 CELLSENMLILEEKEIS-----RILETYWENSNNLLTRESLSQVKLALVINGDFLDKLLV 831
Query: 774 SF---------------------EVRRSFL---DLALSCK-------------------- 789
S + RR FL L+L C+
Sbjct: 832 SLRKEPRALAQNVNMDEAWQELGQSRRDFLYARRLSLLCRRFGLPLAAPPAQDSRARRSS 891
Query: 790 ----------------AVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAH 833
AVICCRV+P QK+ IV +VKK + +TLAIGDGAND+ MI+TA
Sbjct: 892 EVLQERAFVDLASKCQAVICCRVTPKQKALIVALVKKYHQVVTLAIGDGANDINMIKTAD 951
Query: 834 VGVGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIE 893
VGVG++G EGMQA NSD+ + QF +L++LLLVHG WSY R+ K + Y FYK++ +++
Sbjct: 952 VGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLVHGRWSYVRICKFLRYFFYKSMASMMVQ 1011
Query: 894 LWFAFVNGFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNG 953
+WFA NGF+GQ L+E W + L+N++++ LP +G+FE+ + E L P+LY + Q
Sbjct: 1012 VWFACYNGFTGQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQSLEKPELYVVGQKD 1071
Query: 954 EGFNTKVFWGHCINALVHSLILFWFPMKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVC 1013
E FN VF + + SL+ F+ + + D T+G A+ F + + VV C
Sbjct: 1072 ELFNYWVFVQAIAHGVTTSLVNFFMTL-WISRD---TAGPAS---FSDHQSFAVVVALSC 1124
Query: 1014 -LKAGLETTAWTKFSHLAVWGSMLTWLVFFGIYST 1047
L +E K+ ++L L F+ I +T
Sbjct: 1125 LLSITMEVILIIKYWTALCVATILLSLGFYAIMTT 1159
>gi|62632750 ATPase, class VI, type 11B [Homo sapiens]
Length = 1177
Score = 678 bits (1750), Expect = 0.0
Identities = 420/1124 (37%), Positives = 620/1124 (55%), Gaps = 52/1124 (4%)
Query: 28 VRSSLGYKKAEDEMSRATSVGDQLEAPARTIYLNQPHLNKFRDNQISTAKYSVLTFLPRF 87
+R LG+ +R V ++ P +Y Q KF DN+I ++KY+V F+P+
Sbjct: 5 IRQQLGFDPPHQSDTRTIYVANRF--PQNGLYTPQ----KFIDNRIISSKYTVWNFVPKN 58
Query: 88 LYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLIIILTIAGIKEIVEDFKRHKADN 147
L+EQ RR AN +FL I L+Q + D +PT T+ +PL ++T+ IK+ ED+ RH +DN
Sbjct: 59 LFEQFRRVANFYFLIIFLVQLMID-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDN 117
Query: 148 AVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANL 207
VN V+R+G K + VGDIV++ + PAD+VLLSS C+V TA+L
Sbjct: 118 EVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASL 177
Query: 208 DGETNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNLNLDGKS---LVAL 264
DGETNLK + TA +QT L L IEC+ P LY F G + + + + L
Sbjct: 178 DGETNLKTHVAVPETALLQTVANLDTLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPL 237
Query: 265 GPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAPLKRSNVEKVTNVQILVLFGIL 324
GP+ +LLRG +L+NT+ +FG+ VYTG +TK+ N KRS VEK N +++ IL
Sbjct: 238 GPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVIL 297
Query: 325 LVMALVSSAGALYWNRSHG-EKNWYIKKMDTTSDN-----FGYNLLTFIILYNNLIPISL 378
+ A++S+ W ++ WY +K + ++ F + L F++LYN +IPISL
Sbjct: 298 ISEAVISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISL 357
Query: 379 LVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIM 438
VT+E+ K+ + FI WD D+Y+ +D A TS+LNEELGQV+Y+F+DKTGTLT N M
Sbjct: 358 YVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEM 417
Query: 439 NFKKCSIAGVTYGHFP-ELAREPSSDDFCRMPPPCSDSCDFDDPRLLKNIEDRHPTAP-- 495
F++CSI G+ Y L E + D S + T+P
Sbjct: 418 QFRECSINGMKYQEINGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPEN 477
Query: 496 ---CIQE---FLTLLAVCHTVVPEK-------DG--------DNIIYQASSPDEAALVKG 534
I+E F +++CHTV DG + Y ASSPDE ALV+
Sbjct: 478 ETELIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEA 537
Query: 535 AKKLGFVFTARTPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGA 594
A ++G VF + ++ ++ +G+ + + +L++LEF SDR+RMSVIV+ PSG L+ KGA
Sbjct: 538 AARIGIVFIGNSEETMEVKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGA 597
Query: 595 DNVIFERLSKDSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASTILK 654
++ I + +E+T H++ FA +GLRTLC+AY + EYEE K EA T L+
Sbjct: 598 ESSILPKCIGGE--IEKTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQ 655
Query: 655 DRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAIN 714
R ++L ++ IEK+L+LLGATA+EDRLQ V ETI L A IK+WVLTGDK ETA++
Sbjct: 656 QREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVS 715
Query: 715 IGYSCRLVSQNMALILLKEDSLDATRAAITQHCTDLGNLLGKENDV--ALIIDGHTLKYA 772
+ SC + M ++ L D+ A + L + +++ + L++DG +L A
Sbjct: 716 VSLSCGHFHRTMNILELINQKSDSECA---EQLRQLARRITEDHVIQHGLVVDGTSLSLA 772
Query: 773 LSFEVRRSFLDLALSCKAVICCRVSPLQKSEIVDVVK-KRVKAITLAIGDGANDVGMIQT 831
L E + F+++ +C AV+CCR++PLQK++++ ++K K ITLA+GDGANDV MIQ
Sbjct: 773 LR-EHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQE 831
Query: 832 AHVGVGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYI 891
AHVG+GI G EG QA NSDYAIA+F +L KLL VHG + Y R+ + Y FYKNV
Sbjct: 832 AHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFIT 891
Query: 892 IELWFAFVNGFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQ 951
+ + F FS Q L++ + LYN+ FT+LP + E+ + P LY+
Sbjct: 892 PQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDIS 951
Query: 952 NGEGFNTKVFWGHCINALVHSLILFWFPMKALEHDT-VLTSGHATDYLFVGNIVYTYVVV 1010
+ K F I H+ I F+ + DT +L +G G +V+T +V+
Sbjct: 952 KNRLLSIKTFLYWTILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTLVFTVMVI 1011
Query: 1011 TVCLKAGLETTAWTKFSHLAVWGSMLTWLVFFGIYSTI-WPTIPIAPDMRGQATMVLSSA 1069
TV +K LET WT +HL WGS++ + VF Y I WP + + +M +LSS
Sbjct: 1012 TVTVKMALETHFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLG-SQNMYFVFIQLLSSG 1070
Query: 1070 HFWLGLFLVPTACLIEDVAWRAAKHTCKKTLLEEVQELETKSRV 1113
W + L+ CL D+ + T E+ Q ET + +
Sbjct: 1071 SAWFAIILMVVTCLFLDIIKKVFDRHLHPTSTEKAQLTETNAGI 1114
>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
Length = 1134
Score = 670 bits (1728), Expect = 0.0
Identities = 418/1120 (37%), Positives = 611/1120 (54%), Gaps = 74/1120 (6%)
Query: 42 SRATSVGDQLEAPARTIYLNQPHLNKFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFL 101
SR VG + P Y+ Q ++ DN+I ++KY+ F+P+ L+EQ RR AN +FL
Sbjct: 23 SRTIYVGHREPPPGAEAYIPQ----RYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFL 78
Query: 102 FIALLQQIPDVSPTGRYTTLVPLIIILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGM 161
I L+Q I D +PT T+ +PL ++T+ IK+ ED+ RHKADNA+N+ +++G
Sbjct: 79 IIFLVQLIID-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGK 137
Query: 162 WHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSH 221
+++ VGDIV V + P D++ LSS+ C+V TA+LDGE++ K +
Sbjct: 138 LVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQD 197
Query: 222 TADMQTREVLMKLSGTIECEGPNRHLYDFTGNLN----LDGKSLVALGPDQILLRGTQLR 277
T T E + L TIECE P LY F G +N L+ + LG + +LLRG L+
Sbjct: 198 TKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLK 257
Query: 278 NTQWVFGIVVYTGHDTKLMQNSTKAPLKRSNVEKVTNVQILVLFGILLVMALVSSAGALY 337
NT+ +FG+ +YTG +TK+ N KRS VEK N ++V IL+ AL+++
Sbjct: 258 NTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYM 317
Query: 338 W-NRSHGEKNWYIKKMDTTSDNFGY-----NLLTFIILYNNLIPISLLVTLEVVKYTQAL 391
W + ++ WY +K ++ + + L F++L+N +IP+S+ VT+E+ K+ +
Sbjct: 318 WQSEPFRDEPWYNQKTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSY 377
Query: 392 FINWDTDMYYIGNDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYG 451
FI WD DM+ + TS+LNEELGQV+Y+F+DKTGTLT N M FK+C I G Y
Sbjct: 378 FITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVY- 436
Query: 452 HFPELAREPSSDDFCR-MPPPCSDSCDFDDPRLLKNIEDRHPTAPCIQEFLTLLAVCHTV 510
P + C P S D D N +R + F L +CHTV
Sbjct: 437 -VPHV--------ICNGQVLPESSGIDMIDSSPSVNGRERE------ELFFRALCLCHTV 481
Query: 511 VPEKD------------GDNIIYQASSPDEAALVKGAKKLGFVFTA-RTPFSVIIEAMGQ 557
+ D G + +Y +SSPDE ALV+G ++LGF + + + I+
Sbjct: 482 QVKDDDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRENH 541
Query: 558 EQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFERLSKDSKYMEETLCHLE 617
+ F +L +L F S R+RMSVIV++ +G + L+CKGAD+ IF R+ + +++ +E
Sbjct: 542 IERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGK--VDQIRARVE 599
Query: 618 YFATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGAT 677
A EGLRTLCVAY L + EYE K+ Q A L+DR ++L E YE IEK+L LLGAT
Sbjct: 600 RNAVEGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGAT 659
Query: 678 AIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLK----- 732
A+EDRLQ +TI L KA IK+WVLTGDK ETA Y+C+L +N L+ L
Sbjct: 660 AVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLLELTTKRIE 719
Query: 733 ----EDSLDATRAAITQHC-----TDLGNLLGKENDVALIIDGHTLKYAL-------SFE 776
D L + +H +L L D LIIDG L + S
Sbjct: 720 EQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGN 779
Query: 777 VRRSFLDLALSCKAVICCRVSPLQKSEIVDVVK-KRVKAITLAIGDGANDVGMIQTAHVG 835
R FL++ SC AV+CCR++PLQK++IV ++K + ITLAIGDGANDV MI AHVG
Sbjct: 780 YRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVG 839
Query: 836 VGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELW 895
+G+ G EG QA NSDYAI +F +L+K+LLVHG + Y R+++ + Y FYKNV +
Sbjct: 840 IGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFL 899
Query: 896 FAFVNGFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEG 955
+ F GFS Q L++ + LYN+ FT+LP + E+ + + R P LY+
Sbjct: 900 YQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNAL 959
Query: 956 FNTKVFWGHCINALVHSLILFWFPMKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCLK 1015
+VF + L +L+ F+ E+ TV ++G G +V+T +V TV LK
Sbjct: 960 LRWRVFIYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLK 1019
Query: 1016 AGLETTAWTKFSHLAVWGSMLTWLVFFGIY-STIWPTIPIAPDMRGQATMVLSSAHFWLG 1074
L+T WT +H +WGS+L ++VF ++ IWP + M +LSS WL
Sbjct: 1020 LALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNY-QRMYYVFIQMLSSGPAWLA 1078
Query: 1075 LFLVPTACLIEDVAWRAAKHTCKKTLLEEVQELETKSRVL 1114
+ L+ T L+ DV K C++ + ++TKS+ L
Sbjct: 1079 IVLLVTISLLPDV---LKKVLCRQLWPTATERVQTKSQCL 1115
>gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]
Length = 1191
Score = 667 bits (1721), Expect = 0.0
Identities = 416/1111 (37%), Positives = 604/1111 (54%), Gaps = 71/1111 (6%)
Query: 42 SRATSVGDQLEAPARTIYLNQPHLNKFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFL 101
SR VG + P Y+ Q ++ DN+I ++KY+ F+P+ L+EQ RR AN +FL
Sbjct: 23 SRTIYVGHREPPPGAEAYIPQ----RYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFL 78
Query: 102 FIALLQQIPDVSPTGRYTTLVPLIIILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGM 161
I L+Q I D +PT T+ +PL ++T+ IK+ ED+ RHKADNA+N+ +++G
Sbjct: 79 IIFLVQLIID-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGK 137
Query: 162 WHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSH 221
+++ VGDIV V + P D++ LSS+ C+V TA+LDGE++ K +
Sbjct: 138 LVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQD 197
Query: 222 TADMQTREVLMKLSGTIECEGPNRHLYDFTGNLN----LDGKSLVALGPDQILLRGTQLR 277
T T E + L TIECE P LY F G +N L+ + LG + +LLRG L+
Sbjct: 198 TKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLK 257
Query: 278 NTQWVFGIVVYTGHDTKLMQNSTKAPLKRSNVEKVTNVQILVLFGILLVMALVSSAGALY 337
NT+ +FG+ +YTG +TK+ N KRS VEK N ++V IL+ AL+++
Sbjct: 258 NTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYM 317
Query: 338 W-NRSHGEKNWYIKKMDTTSDNFGY-----NLLTFIILYNNLIPISLLVTLEVVKYTQAL 391
W + ++ WY +K ++ + + L F++L+N +IP+S+ VT+E+ K+ +
Sbjct: 318 WQSEPFRDEPWYNQKTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSY 377
Query: 392 FINWDTDMYYIGNDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYG 451
FI WD DM+ + TS+LNEELGQV+Y+F+DKTGTLT N M FK+C I G Y
Sbjct: 378 FITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVY- 436
Query: 452 HFPELAREPSSDDFCR-MPPPCSDSCDFDDPRLLKNIEDRHPTAPCIQEFLTLLAVCHTV 510
P + C P S D D N +R + F L +CHTV
Sbjct: 437 -VPHV--------ICNGQVLPESSGIDMIDSSPSVNGRERE------ELFFRALCLCHTV 481
Query: 511 VPEKD------------GDNIIYQASSPDEAALVKGAKKLGFVFTA-RTPFSVIIEAMGQ 557
+ D G + +Y +SSPDE ALV+G ++LGF + + + I+
Sbjct: 482 QVKDDDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRENH 541
Query: 558 EQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFERLSKDSKYMEETLCHLE 617
+ F +L +L F S R+RMSVIV++ +G + L+CKGAD+ IF R+ + +++ +E
Sbjct: 542 IERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGK--VDQIRARVE 599
Query: 618 YFATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGAT 677
A EGLRTLCVAY L + EYE K+ Q A L+DR ++L E YE IEK+L LLGAT
Sbjct: 600 RNAVEGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGAT 659
Query: 678 AIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLK----- 732
A+EDRLQ +TI L KA IK+WVLTGDK ETA Y+C+L +N L+ L
Sbjct: 660 AVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLLELTTKRIE 719
Query: 733 ----EDSLDATRAAITQHC-----TDLGNLLGKENDVALIIDGHTLKYAL-------SFE 776
D L + +H +L L D LIIDG L + S
Sbjct: 720 EQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGN 779
Query: 777 VRRSFLDLALSCKAVICCRVSPLQKSEIVDVVK-KRVKAITLAIGDGANDVGMIQTAHVG 835
R FL++ SC AV+CCR++PLQK++IV ++K + ITLAIGDGANDV MI AHVG
Sbjct: 780 YRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVG 839
Query: 836 VGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELW 895
+G+ G EG QA NSDYAI +F +L+K+LLVHG + Y R+++ + Y FYKNV +
Sbjct: 840 IGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFL 899
Query: 896 FAFVNGFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEG 955
+ F GFS Q L++ + LYN+ FT+LP + E+ + + R P LY+
Sbjct: 900 YQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNAL 959
Query: 956 FNTKVFWGHCINALVHSLILFWFPMKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCLK 1015
+VF + L +L+ F+ E+ TV ++G G +V+T +V TV LK
Sbjct: 960 LRWRVFIYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLK 1019
Query: 1016 AGLETTAWTKFSHLAVWGSMLTWLVFFGIY-STIWPTIPIAPDMRGQATMVLSSAHFWLG 1074
L+T WT +H +WGS+L ++VF ++ IWP + M +LSS WL
Sbjct: 1020 LALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNY-QRMYYVFIQMLSSGPAWLA 1078
Query: 1075 LFLVPTACLIEDVAWRAAKHTCKKTLLEEVQ 1105
+ L+ T L+ DV + T E VQ
Sbjct: 1079 IVLLVTISLLPDVLKKVLCRQLWPTATERVQ 1109
>gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens]
Length = 1119
Score = 622 bits (1605), Expect = e-178
Identities = 392/1107 (35%), Positives = 586/1107 (52%), Gaps = 79/1107 (7%)
Query: 48 GDQLEAPARTIYLNQPHLN--------KFRDNQISTAKYSVLTFLPRFLYEQIRRAANAF 99
G++ RT+++ ++ +F DN+I ++KY++ FLP+ L+EQ RR AN +
Sbjct: 15 GEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFY 74
Query: 100 FLFIALLQQIPDVSPTGRYTTLVPLIIILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRN 159
FL I L+Q D +PT T+ +PL ++T+ IK+ ED+ RH+ADN VNK ++ N
Sbjct: 75 FLIIFLVQVTVD-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIEN 133
Query: 160 GMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGETNLKIRQGL 219
+++ VGD+V+V + P D++LLSS CYV TA+LDGE+N K +
Sbjct: 134 AKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAV 193
Query: 220 SHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNLNLDGKSLVA----LGPDQILLRGTQ 275
T + T E + L IECE P LY F G +N+ SL A LGP+ +LL+G
Sbjct: 194 RDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGAT 253
Query: 276 LRNTQWVFGIVVYTGHDTKLMQNSTKAPLKRSNVEKVTNVQILVLFGILLVMALVSSAGA 335
L+NT+ ++G+ VYTG +TK+ N KRS VEK N ++V ILL A V +
Sbjct: 254 LKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLK 313
Query: 336 LYWNRS-HGEKNWYIKKMDTTSDNFGY-----NLLTFIILYNNLIPISLLVTLEVVKYTQ 389
W + + ++ WY +K + + L+F++L+N +IP+S+ VT+E+ K+
Sbjct: 314 YVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLG 373
Query: 390 ALFINWDTDMYYIGNDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVT 449
+ FI+WD D Y + A+ TS+LNEELGQV Y+F+DKTGTLT N M F +C I G
Sbjct: 374 SFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHK 433
Query: 450 YGHFPELAREPSSDDFCRMPPPCSDSCDFDDPRLLKNIEDRHPTAPCIQEFLTLLAVCHT 509
Y + S D FD ++ KN E+ FL L +CHT
Sbjct: 434 YKGVTQEVDGLSQTD--------GTLTYFD--KVDKNREEL---------FLRALCLCHT 474
Query: 510 VVPE--------KDGDNIIYQASSPDEAALVKGAKKLGFVFTARTPFSVIIEAMGQE-QT 560
V + + + Y +SSPDE ALVKGAK+ GF F + +E +E +
Sbjct: 475 VEIKTNDAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEE 534
Query: 561 FGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFERLSKDSKYMEETLCHLEYFA 620
+ +L+ L F + R+RMSVIV+T G + L+CKGAD+ +F R+ +E T H+E A
Sbjct: 535 YELLHTLNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHE--IELTKVHVERNA 592
Query: 621 TEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAIE 680
+G RTLCVA+ +++ ++YE + EA L+DR +++E+ ++ IE N+ L+GATA+E
Sbjct: 593 MDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVE 652
Query: 681 DRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILL--------- 731
D+LQ ETI L A +K+WVLTGDK ETA + Y+CRL N L+ L
Sbjct: 653 DKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESE 712
Query: 732 -KEDSLDATRA--------AITQHCTDLGNLLGKENDVALIIDGHTLKYAL-------SF 775
KED L + + + LIIDG TL L S
Sbjct: 713 RKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSN 772
Query: 776 EVRRSFLDLALSCKAVICCRVSPLQKSEIVDVVKK-RVKAITLAIGDGANDVGMIQTAHV 834
+ FL + + C AV+CCR++PLQK++IV +VK + ITL+IGDGANDV MI +HV
Sbjct: 773 NYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHV 832
Query: 835 GVGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIEL 894
G+GI G EG QA NSDY++ +F +L+KLLL HG Y R+ + Y FYKN+ + +
Sbjct: 833 GIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQF 892
Query: 895 WFAFVNGFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGE 954
+ F GFS Q L++ + +YN+ FT+LP + E+ +++ P+LY
Sbjct: 893 LYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNA 952
Query: 955 GFNTKVFWGHCINALVHSLILFWFPMKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCL 1014
F A + F+ + ++ +G G IV+T +V TV L
Sbjct: 953 MLQLGPFLYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTL 1012
Query: 1015 KAGLETTAWTKFSHLAVWGSMLTWLVFFGIY--STIWPTIPIAPDMRGQATMVLSSAHFW 1072
K L+T WT +H +WGS L + VFF + IWP + M +LSS W
Sbjct: 1013 KLALDTRFWTWINHFVIWGS-LAFYVFFSFFWGGIIWPFLK-QQRMYFVFAQMLSSVSTW 1070
Query: 1073 LGLFLVPTACLIEDVAWRAAKHTCKKT 1099
L + L+ L ++ K+ +++
Sbjct: 1071 LAIILLIFISLFPEILLIVLKNVRRRS 1097
>gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens]
Length = 1132
Score = 622 bits (1605), Expect = e-178
Identities = 392/1107 (35%), Positives = 586/1107 (52%), Gaps = 79/1107 (7%)
Query: 48 GDQLEAPARTIYLNQPHLN--------KFRDNQISTAKYSVLTFLPRFLYEQIRRAANAF 99
G++ RT+++ ++ +F DN+I ++KY++ FLP+ L+EQ RR AN +
Sbjct: 15 GEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFY 74
Query: 100 FLFIALLQQIPDVSPTGRYTTLVPLIIILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRN 159
FL I L+Q D +PT T+ +PL ++T+ IK+ ED+ RH+ADN VNK ++ N
Sbjct: 75 FLIIFLVQVTVD-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIEN 133
Query: 160 GMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGETNLKIRQGL 219
+++ VGD+V+V + P D++LLSS CYV TA+LDGE+N K +
Sbjct: 134 AKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAV 193
Query: 220 SHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNLNLDGKSLVA----LGPDQILLRGTQ 275
T + T E + L IECE P LY F G +N+ SL A LGP+ +LL+G
Sbjct: 194 RDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGAT 253
Query: 276 LRNTQWVFGIVVYTGHDTKLMQNSTKAPLKRSNVEKVTNVQILVLFGILLVMALVSSAGA 335
L+NT+ ++G+ VYTG +TK+ N KRS VEK N ++V ILL A V +
Sbjct: 254 LKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLK 313
Query: 336 LYWNRS-HGEKNWYIKKMDTTSDNFGY-----NLLTFIILYNNLIPISLLVTLEVVKYTQ 389
W + + ++ WY +K + + L+F++L+N +IP+S+ VT+E+ K+
Sbjct: 314 YVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLG 373
Query: 390 ALFINWDTDMYYIGNDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVT 449
+ FI+WD D Y + A+ TS+LNEELGQV Y+F+DKTGTLT N M F +C I G
Sbjct: 374 SFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHK 433
Query: 450 YGHFPELAREPSSDDFCRMPPPCSDSCDFDDPRLLKNIEDRHPTAPCIQEFLTLLAVCHT 509
Y + S D FD ++ KN E+ FL L +CHT
Sbjct: 434 YKGVTQEVDGLSQTD--------GTLTYFD--KVDKNREEL---------FLRALCLCHT 474
Query: 510 VVPE--------KDGDNIIYQASSPDEAALVKGAKKLGFVFTARTPFSVIIEAMGQE-QT 560
V + + + Y +SSPDE ALVKGAK+ GF F + +E +E +
Sbjct: 475 VEIKTNDAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEE 534
Query: 561 FGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFERLSKDSKYMEETLCHLEYFA 620
+ +L+ L F + R+RMSVIV+T G + L+CKGAD+ +F R+ +E T H+E A
Sbjct: 535 YELLHTLNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHE--IELTKVHVERNA 592
Query: 621 TEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAIE 680
+G RTLCVA+ +++ ++YE + EA L+DR +++E+ ++ IE N+ L+GATA+E
Sbjct: 593 MDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVE 652
Query: 681 DRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILL--------- 731
D+LQ ETI L A +K+WVLTGDK ETA + Y+CRL N L+ L
Sbjct: 653 DKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESE 712
Query: 732 -KEDSLDATRA--------AITQHCTDLGNLLGKENDVALIIDGHTLKYAL-------SF 775
KED L + + + LIIDG TL L S
Sbjct: 713 RKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSN 772
Query: 776 EVRRSFLDLALSCKAVICCRVSPLQKSEIVDVVKK-RVKAITLAIGDGANDVGMIQTAHV 834
+ FL + + C AV+CCR++PLQK++IV +VK + ITL+IGDGANDV MI +HV
Sbjct: 773 NYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHV 832
Query: 835 GVGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIEL 894
G+GI G EG QA NSDY++ +F +L+KLLL HG Y R+ + Y FYKN+ + +
Sbjct: 833 GIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQF 892
Query: 895 WFAFVNGFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGE 954
+ F GFS Q L++ + +YN+ FT+LP + E+ +++ P+LY
Sbjct: 893 LYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNA 952
Query: 955 GFNTKVFWGHCINALVHSLILFWFPMKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCL 1014
F A + F+ + ++ +G G IV+T +V TV L
Sbjct: 953 MLQLGPFLYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTL 1012
Query: 1015 KAGLETTAWTKFSHLAVWGSMLTWLVFFGIY--STIWPTIPIAPDMRGQATMVLSSAHFW 1072
K L+T WT +H +WGS L + VFF + IWP + M +LSS W
Sbjct: 1013 KLALDTRFWTWINHFVIWGS-LAFYVFFSFFWGGIIWPFLK-QQRMYFVFAQMLSSVSTW 1070
Query: 1073 LGLFLVPTACLIEDVAWRAAKHTCKKT 1099
L + L+ L ++ K+ +++
Sbjct: 1071 LAIILLIFISLFPEILLIVLKNVRRRS 1097
>gi|65301139 ATPase, class II, type 9A [Homo sapiens]
Length = 1047
Score = 439 bits (1128), Expect = e-122
Identities = 299/1003 (29%), Positives = 496/1003 (49%), Gaps = 92/1003 (9%)
Query: 52 EAPARTIYLNQPHLN--KFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQI 109
EA RT++L P ++ N I+ KY+ TFLP L+ Q + N +FL +A Q +
Sbjct: 35 EARPRTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFV 94
Query: 110 PDVSPTGRYTTLVPLIIILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKE 169
P++ YT VPL +L + I+E VE+ + + D VN + L +
Sbjct: 95 PEMRLGALYTYWVPLGFVLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSN 154
Query: 170 VAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADMQTRE 229
+ VGD++ V Q +PAD++ L +SE C++ T LDGET+ K+R ++ T + T
Sbjct: 155 IQVGDLIIVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAA 214
Query: 230 VLMKLSGTIECEGPNRHLYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQW-------- 281
L+++ + E PN +++F G + D + + NT W
Sbjct: 215 DLLQIRSYVYAEEPNIDIHNFVGTFTREDS-------DPPISESLSIENTLWAGTVVASG 267
Query: 282 -VFGIVVYTGHDTKLMQNSTKAPLKRSNVEKVTNVQILVLFGILLVMALVSSAGALYWNR 340
V G+V+YTG + + + N++ K + N +LFG L+V++LV A
Sbjct: 268 TVVGVVLYTGRELRSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMVA------L 321
Query: 341 SHGEKNWYIKKMDTTSDNFGYNLLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMY 400
H WY++ ++ F++L++N+IPISL V L++ K + I D+ +
Sbjct: 322 QHFAGRWYLQ------------IIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKI- 368
Query: 401 YIGNDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREP 460
+ R+S + E+LG++ YL +DKTGTLT N M FK+ + V YG + E
Sbjct: 369 -----PGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGL--DSMDEV 421
Query: 461 SSDDFCRMPPPCSDSCDFDDPRLLKNIEDRHPTAPCIQEFLTLLAVCHTVVPEKDGDNI- 519
S F D P L + R + + E + +A+CH V P + + +
Sbjct: 422 QSHIFSIYTQQSQDPPAQKGPTLTTKV--RRTMSSRVHEAVKAIALCHNVTPVYESNGVT 479
Query: 520 --------------IYQASSPDEAALVKGAKKLGFVFTARTPFSVIIEAMGQE-QTFGIL 564
+YQASSPDE ALV+ + +G R S+ + G + F IL
Sbjct: 480 DQAEAEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTIL 539
Query: 565 NVLEFSSDRKRMSVIVRTPS-GRLRLYCKGADNVIFERLSKDSKYMEETLCHLEYFATEG 623
+ F+ + KRM +IVR S G + Y KGAD V+ + + + ++EE ++ A EG
Sbjct: 540 QIFPFTYESKRMGIIVRDESTGEITFYMKGAD-VVMAGIVQYNDWLEEECGNM---AREG 595
Query: 624 LRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAIEDRL 683
LR L VA L+E +Y+++ Y +A + DR+ ++ E +E + LL T +ED+L
Sbjct: 596 LRVLVVAKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQL 655
Query: 684 QAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAI 743
QA V T+ TL A IK+W+LTGDK ETA + LV++N + + + L R
Sbjct: 656 QADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFR---LVTNRGEA 712
Query: 744 TQHCTDLGNLLGKENDVALIIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPLQKSE 803
N +++D AL+I G +L+ L + F++LA C AV+CCR +P QK++
Sbjct: 713 HLEL----NAFRRKHDCALVISGDSLEVCLKY-YEYEFMELACQCPAVVCCRCAPTQKAQ 767
Query: 804 IVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFSYLEKL 863
IV ++++R +T A+GDG NDV MIQ + GVG+ G EG QA+ +D++I QF +L +L
Sbjct: 768 IVRLLQERTGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRL 827
Query: 864 LLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNVIFTAL 923
L+VHG SY R + ++++ + ++ F+ V F+ L++ + I Y+ I+T
Sbjct: 828 LMVHGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMF 887
Query: 924 PPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKVFWGHCINALVHSLILFWFPMKAL 983
P F+L + ++ E + +P+LYK G + K F L W +
Sbjct: 888 PVFSL-VLDKDVKSEVAMLYPELYKDLLKGRPLSYKTF-------------LIWVLISIY 933
Query: 984 EHDTVLTSG---HATDYLFVGNIVYTYVVVTVCLKAGLETTAW 1023
+ T++ ++++ + I +T +++T L L W
Sbjct: 934 QGSTIMYGALLLFESEFVHIVAISFTSLILTELLMVALTIQTW 976
>gi|41327760 ATPase, class II, type 9B [Homo sapiens]
Length = 1147
Score = 423 bits (1087), Expect = e-118
Identities = 313/1046 (29%), Positives = 503/1046 (48%), Gaps = 117/1046 (11%)
Query: 52 EAPARTIYLNQPHL--NKFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQI 109
E ART++L P K N I KY+V TF+P LYEQ + N +FL I+ Q +
Sbjct: 112 ELKARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFV 171
Query: 110 PDVSPTGRYTTLVPLIIILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKE 169
P + YT PL +L + +E +++F+R + D VN + L + +
Sbjct: 172 PALKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSD 231
Query: 170 VAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADMQTRE 229
+ VGD++ V Q +P+D+V L +SE C++ T LDGET+ K++ +S T +
Sbjct: 232 IQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALG 291
Query: 230 VLMKLSGTIECEGPNRHLYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQW-------- 281
L +S + + P ++ F G + D + + NT W
Sbjct: 292 DLFSISAYVYAQKPQMDIHSFEGTFTREDS-------DPPIHESLSIENTLWASTIVASG 344
Query: 282 -VFGIVVYTGHDTKLMQNST----KAPLKRSNVEKVTNVQILVLFGILLVMALVSSAGAL 336
V G+V+YTG +T+ + N++ K L + ++T L L + +VM +
Sbjct: 345 TVIGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVG- 403
Query: 337 YWNRSHGEKNWYIKKMDTTSDNFGYNLLTFIILYNNLIPISLLVTLEVVKYTQALFINWD 396
WY NL F++L++ +IPISL V L++ K + D
Sbjct: 404 ---------PWY------------RNLFRFLLLFSYIIPISLRVNLDMGKAVYGWMMMKD 442
Query: 397 TDMYYIGNDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYG-HFPE 455
N + RTS + EELG++ YL +DKTGTLT N M FK+ + V+YG +
Sbjct: 443 E------NIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMD 496
Query: 456 LAREPSSDDFCRMPPPCSDS---------CDFDDPRLLKNIEDRHPTAPCIQEFLTLLAV 506
+ D + +M + P++ K++ R I E + + +
Sbjct: 497 EIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSR------IHEAVKAIVL 550
Query: 507 CHTVVP---------------EKDGD----NIIYQASSPDEAALVKGAKKLGFVFTARTP 547
CH V P E D D N YQASSPDE ALV+ + +G +R
Sbjct: 551 CHNVTPVYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDL 610
Query: 548 FSVIIEA-MGQEQTFGILNVLEFSSDRKRMSVIVRTPS-GRLRLYCKGADNVIFERLSKD 605
S+ ++ GQ +F IL + F+S+ KRM VIVR S + Y KGAD V + +
Sbjct: 611 TSMQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGAD-VAMSPIVQY 669
Query: 606 SKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYE 665
+ ++EE ++ A EGLRTL VA L+E +Y+++ Y +A + DR+ ++ E
Sbjct: 670 NDWLEEECGNM---AREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVE 726
Query: 666 IIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQN 725
+E+ + LL T +ED+LQA V T+ L A IKIW+LTGDK ETA I S LVS+
Sbjct: 727 SLEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRT 786
Query: 726 MALILLKEDSLDATRAAITQHCTDLGNLLGKENDVALIIDGHTLKYALSFEVRRSFLDLA 785
+ + ++ + +R N +++D AL+I G +L+ L + F++LA
Sbjct: 787 QDIHIFRQVT---SRGEAHLEL----NAFRRKHDCALVISGDSLEVCLKY-YEHEFVELA 838
Query: 786 LSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQ 845
C AV+CCR SP QK+ IV ++++ T AIGDG NDV MIQ A G+GI G EG Q
Sbjct: 839 CQCPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQ 898
Query: 846 ATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQ 905
A+ +D++I QF ++ +LL+VHG SY R + ++ +++ ++ F+ V F+
Sbjct: 899 ASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASV 958
Query: 906 ILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKVFWGHC 965
L++ + + Y I+T P F+L + ++ E + +P+LYK G + K F
Sbjct: 959 PLYQGFLMVGYATIYTMFPVFSL-VLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWV 1017
Query: 966 INALVHSLILFWFPMKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCLKAGLETTAW-- 1023
+ ++ IL + + E ++++ V I +T +++T L L W
Sbjct: 1018 LISIYQGGILMYGALVLFE----------SEFVHVVAISFTALILTELLMVALTVRTWHW 1067
Query: 1024 ----TKFSHLAVWGSMLTWL-VFFGI 1044
+F L + S L +L +FGI
Sbjct: 1068 LMVVAEFLSLGCYVSSLAFLNEYFGI 1093
>gi|149944474 ATPase, class V, type 10B [Homo sapiens]
Length = 1461
Score = 410 bits (1053), Expect = e-114
Identities = 237/631 (37%), Positives = 347/631 (54%), Gaps = 55/631 (8%)
Query: 521 YQASSPDEAALVKGAKKLGFVFTARTPFSVIIEA-MGQEQTFGILNVLEFSSDRKRMSVI 579
Y+A SPDEAALV A F +RTP V + G TF +L L F S RKRMSV+
Sbjct: 717 YEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRMSVV 776
Query: 580 VRTP-SGRLRLYCKGADNVIFERLS------------KDSKYMEETLCHLEYFATEGLRT 626
VR P +G + +Y KGAD+VI + L K K T HL+ +A +GLRT
Sbjct: 777 VRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRT 836
Query: 627 LCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAG 686
LC+A +SE ++ W +EA L +R + L E + +E L LLGAT IEDRLQ G
Sbjct: 837 LCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEG 896
Query: 687 VPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAITQH 746
VP+TIATL +A I++WVLTGDKQETA+NI +SCRL++Q + + ++ + + +
Sbjct: 897 VPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCA 956
Query: 747 CTDLGNLLGKEN------------------------DVALIIDGHTLKYALSFEVRRSFL 782
+L + + L+IDG TL ++ + FL
Sbjct: 957 LEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQGKLEKKFL 1016
Query: 783 DLALSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNE 842
+L C++V+CCR +PLQKS IV +V+ +++ +TL+IGDGANDV MIQ A +G+GISG E
Sbjct: 1017 ELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQE 1076
Query: 843 GMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGF 902
GMQA +SD+AI +F +L+KLLLVHG W Y+R+ + ++Y YKNV + W+ F GF
Sbjct: 1077 GMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGF 1136
Query: 903 SGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKVFW 962
S + + W + +N+ FT+LPP G+ ++ + E++L P+LYK QN E +N FW
Sbjct: 1137 SSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFW 1196
Query: 963 GHCINALVHSLILFWFPMKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCLKAGLETTA 1022
++A SLI F+ P A + G D G + T + T+ L +E
Sbjct: 1197 ISMVDAFYQSLICFFIPYLAYK-------GSDIDVFTFGTPINTISLTTILLHQAMEMKT 1249
Query: 1023 WTKFSHLAVWGSMLTWLVFFGIYSTIW-----PTIPIAPDMRGQATMVLSSAHFWLGLFL 1077
WT F + + GS L + + +Y+ PT P M GQ LS+ F+L FL
Sbjct: 1250 WTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWV-MEGQ----LSNPTFYLVCFL 1304
Query: 1078 VPTACLIEDVAWRAAKHTCKKTLLEEVQELE 1108
P L+ + + + TC K+L+ + Q+++
Sbjct: 1305 TPVVALLPRYFFLSLQGTCGKSLISKAQKID 1335
Score = 283 bits (723), Expect = 9e-76
Identities = 158/404 (39%), Positives = 230/404 (56%), Gaps = 29/404 (7%)
Query: 67 KFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLII 126
++ N+ T KY++ TFLPR L+EQ R AN +FLF+ +L +P + R T++PL I
Sbjct: 65 RYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAI 124
Query: 127 ILTIAGIKEIVEDFKRHKADNAVN---------KKKTIVLRNGMWHTIMWKEVAVGDIVK 177
+L + IK+ +EDFKRH+ D A+N K++T V + WK+V VGD ++
Sbjct: 125 VLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQK-------CWKDVRVGDFIQ 177
Query: 178 VVNGQYLPADVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGT 237
+ + +PAD++LL SS+P +C++ETA+LDGETNLK R + + + + T
Sbjct: 178 MKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNT 237
Query: 238 IECEGPNRHLYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQ 297
I CE PN HL F G + ++ G + +LLRG +RNT+ GIV+Y GH+TK M
Sbjct: 238 IVCEKPNNHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAML 297
Query: 298 NSTKAPLKRSNVEKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSD 357
N++ KRS +E+ N+ I GIL++M L+ + G WN + E D
Sbjct: 298 NNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEH----PPFDVPDA 353
Query: 358 NFG---------YNLLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPA 408
N Y LT IIL LIPISL V++E+VK Q F++ D D+Y D
Sbjct: 354 NGSFLPSALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSI 413
Query: 409 MARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGH 452
R N+ E+LGQ++Y+FSDKTGTLT N M F++C+I G Y H
Sbjct: 414 QCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSH 457
>gi|222352161 ATPase, class V, type 10D [Homo sapiens]
Length = 1426
Score = 400 bits (1028), Expect = e-111
Identities = 230/568 (40%), Positives = 333/568 (58%), Gaps = 42/568 (7%)
Query: 518 NIIYQASSPDEAALVKGAKKLGFVFTARTPFSVIIE--AMGQEQTFGILNVLEFSSDRKR 575
N+ Y+A SPDEAALV A+ +RTP V+++ A+G TF +L++L F S RKR
Sbjct: 720 NLCYEAESPDEAALVYAARAYQCTLRSRTPEQVMVDFAALGP-LTFQLLHILPFDSVRKR 778
Query: 576 MSVIVRTP-SGRLRLYCKGADNVIFERLSKDSK-----------YMEETLCHLEYFATEG 623
MSV+VR P S ++ +Y KGAD+VI E LS S E+T HL+ +A +G
Sbjct: 779 MSVVVRHPLSNQVVVYTKGADSVIMELLSVASPDGASLEKQQMIVREKTQKHLDDYAKQG 838
Query: 624 LRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAIEDRL 683
LRTLC+A +S+ EY EWL+ + A T + +R + L E +E L LLGAT IEDRL
Sbjct: 839 LRTLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRL 898
Query: 684 QAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAI 743
Q GVPE+I L KA IKIW+LTGDKQETA+NI Y+C+L+ + L +L S DA +
Sbjct: 899 QEGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSKDACGMLM 958
Query: 744 TQHCTDLGNL-------LGKENDV-------------ALIIDGHTLKYALSFEVRRSFLD 783
+ +L + D+ LII G TL++AL +++ FL+
Sbjct: 959 STILKELQKKTQALPEQVSLSEDLLQPPVPRDSGLRAGLIITGKTLEFALQESLQKQFLE 1018
Query: 784 LALSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEG 843
L C+AV+CCR +PLQKSE+V +V+ ++ +TLAIGDGANDV MIQ A +G+G+SG EG
Sbjct: 1019 LTSWCQAVVCCRATPLQKSEVVKLVRSHLQVMTLAIGDGANDVSMIQVADIGIGVSGQEG 1078
Query: 844 MQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFS 903
MQA SD+A++QF +L KLLLVHG W Y R++ ILY FYKNV + W+ F GFS
Sbjct: 1079 MQAVMASDFAVSQFKHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFS 1138
Query: 904 GQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKVFWG 963
G + + W + +N++FT+ PP G+ E+ + E++++ P+LY+ Q E + FW
Sbjct: 1139 GTSMTDYWVLIFFNLLFTSAPPVIYGVLEKDVSAETLMQLPELYRSGQKSEAYLPHTFWI 1198
Query: 964 HCINALVHSLILFWFPMKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCLKAGLETTAW 1023
++A SL+ F+ P + G TD GN + T + V L +E+ +
Sbjct: 1199 TLLDAFYQSLVCFFVPYFTYQ-------GSDTDIFAFGNPLNTAALFIVLLHLVIESKSL 1251
Query: 1024 TKFSHLAVWGSMLTWLVFFGIYSTIWPT 1051
T L + GS+L++ +F ++ + T
Sbjct: 1252 TWIHLLVIIGSILSYFLFAIVFGAMCVT 1279
Score = 289 bits (739), Expect = 1e-77
Identities = 164/409 (40%), Positives = 234/409 (57%), Gaps = 20/409 (4%)
Query: 63 PHLNKFRD-----------NQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPD 111
PH+ F+D N+I T KY++L F+PR L+EQ RAAN +FLF+ +L +P
Sbjct: 55 PHIQPFKDEYEKFSGAYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPL 114
Query: 112 VSPTGRYTTLVPLIIILTIAGIKEIVEDFKRHKADNAVNKKKTIVL--RNGMWHTIMWKE 169
V + T++PL+++LTI IK+ +ED++++K D +N T V + + WK+
Sbjct: 115 VEAFQKEITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDRCWKD 174
Query: 170 VAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADMQTRE 229
V VGD +++ + +PAD+VLL S++P +C++ET+ LDGE+NLK RQ + A+ +
Sbjct: 175 VTVGDFIRLSCNEVIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEV 234
Query: 230 VLMKLSGTIECEGPNRHLYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYT 289
K S IECE PN L F G L K V L + +LLRG +RNT+ V GIVVY
Sbjct: 235 DPEKFSSRIECESPNNDLSRFRGFLEHSNKERVGLSKENLLLRGCTIRNTEAVVGIVVYA 294
Query: 290 GHDTKLMQNSTKAPLKRSNVEKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEKNWYI 349
GH+TK M N++ KRS +E+ N +L +L++M L + G W S EK +
Sbjct: 295 GHETKAMLNNSGPRYKRSKLERRANTDVLWCVMLLVIMCLTGAVGHGIW-LSRYEKMHFF 353
Query: 350 KKMDTTSDNFG------YNLLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIG 403
+ Y T IIL LIPISL V++E+VK Q FI D D Y
Sbjct: 354 NVPEPDGHIISPLLAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEK 413
Query: 404 NDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGH 452
D+ R N+ E+LGQ++YLFSDKTGTLT N M F++CS+AG Y H
Sbjct: 414 MDSIVQCRALNIAEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCH 462
>gi|14424433 ATPase, class V, type 10A [Homo sapiens]
Length = 1499
Score = 393 bits (1009), Expect = e-109
Identities = 243/632 (38%), Positives = 346/632 (54%), Gaps = 51/632 (8%)
Query: 521 YQASSPDEAALVKGAKKLGFVFTARTPFSVIIEA--MGQEQTFGILNVLEFSSDRKRMSV 578
Y+A SPDEAALV A+ V R V +E +G+ TF +L+ L F S RKRMSV
Sbjct: 693 YEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGR-LTFELLHTLGFDSVRKRMSV 751
Query: 579 IVRTP-SGRLRLYCKGADNVIFERLSKDS----------KYMEETLCHLEYFATEGLRTL 627
++R P + + +Y KGAD+V+ + L S K +T +L +A EGLRTL
Sbjct: 752 VIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLRTL 811
Query: 628 CVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGV 687
C+A LS+ EY WL+ + EA + L++ + L + +E NL LLGAT IEDRLQ GV
Sbjct: 812 CIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGV 871
Query: 688 PETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAITQ-- 745
PETI+ L +A ++IWVLTGDKQETA+NI Y+C+L+ + +I L S +A A + Q
Sbjct: 872 PETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLDQCL 931
Query: 746 -HCTDLGNLLGKENDV-----------------------ALIIDGHTLKYALSFEVRRSF 781
+ G E +L+IDG +L YAL + F
Sbjct: 932 CYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEKNLEDKF 991
Query: 782 LDLALSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGN 841
L LA C++V+CCR +PLQKS +V +V+ ++KA+TLAIGDGANDV MIQ A VGVGISG
Sbjct: 992 LFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQ 1051
Query: 842 EGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNG 901
EGMQA SD+A+ +F YLE+LL++HG W Y+R+ +LY FYKN + + WF F G
Sbjct: 1052 EGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCG 1111
Query: 902 FSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKVF 961
FS + ++W + +N++F++LPP G+ +R +L PQLYK QN E + + F
Sbjct: 1112 FSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNMEEYRPRTF 1171
Query: 962 WGHCINALVHSLILFWFPMKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCLKAGLETT 1021
W + +A SL+ F P A V D G + T ++T L G+ET
Sbjct: 1172 WFNMADAAFQSLVCFSIPYLAYYDSNV-------DLFTWGTPIVTIALLTFLLHLGIETK 1224
Query: 1022 AWTKFSHLAVWGSMLTWLVFFGIYSTIWPTI--PIAPDMRGQATMVLSSAHFWLGLFLVP 1079
WT + + S+L + IY+ T P P QA +L F+L + P
Sbjct: 1225 TWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSNPYWTMQA--LLGDPVFYLTCLMTP 1282
Query: 1080 TACLIEDVAWRAAKHTCKKTLLEEVQELETKS 1111
A L+ + +R+ + T L+ ++L KS
Sbjct: 1283 VAALLPRLFFRSLQGRVFPTQLQLARQLTRKS 1314
Score = 292 bits (747), Expect = 1e-78
Identities = 159/391 (40%), Positives = 235/391 (60%), Gaps = 8/391 (2%)
Query: 70 DNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLIIILT 129
DN++ T KY++L+FLP+ L+EQ R AN +F+FIALL +P V+ L P++ IL
Sbjct: 61 DNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILA 120
Query: 130 IAGIKEIVEDFKRHKADNAVNKKKTIVL--RNGMWHTIMWKEVAVGDIVKVVNGQYLPAD 187
I +++ ED+ RH++D+ +N +V + WKE+ VGD V++ + PAD
Sbjct: 121 ITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPAD 180
Query: 188 VVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRHL 247
++LLSSS+P +C++ETANLDGETNLK RQ + +++ + + + IECE PN L
Sbjct: 181 ILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDL 240
Query: 248 YDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAPLKRS 307
F G + D L + +LLRG LRNT V GIV+Y GH+TK + N++ KRS
Sbjct: 241 SRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRS 300
Query: 308 NVEKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEKN--WYIKKMDTTS----DNFGY 361
+E+ N +L +L+ M+L S+ G W + EK +Y+ K D +S Y
Sbjct: 301 KLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVY 360
Query: 362 NLLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELGQ 421
+ LT II+ LIPISL V++E+VK Q FIN D +Y D+ R N+ E+LGQ
Sbjct: 361 SFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQ 420
Query: 422 VKYLFSDKTGTLTCNIMNFKKCSIAGVTYGH 452
++Y+FSDKTGTLT N M F++C+++GV Y H
Sbjct: 421 IQYIFSDKTGTLTENKMVFRRCTVSGVEYSH 451
>gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo
sapiens]
Length = 387
Score = 266 bits (680), Expect = 9e-71
Identities = 142/383 (37%), Positives = 222/383 (57%), Gaps = 29/383 (7%)
Query: 67 KFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLII 126
++ N I T+KY++LTFLP L+EQ + AN +FLF+ +LQ IP +S +TT+VPL++
Sbjct: 28 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87
Query: 127 ILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPA 186
+LTI +K+ +D+ RHK+DN VN +++ VL NG+ W V VGDI+K+ N Q++ A
Sbjct: 88 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 147
Query: 187 DVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRH 246
D++LLSSSEP +CY+ETA LDGETN+K+RQ + T+++ L K G + CE PN
Sbjct: 148 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 207
Query: 247 LYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAPLKR 306
L F+G L ++ L +LLRG LRNT+W FG+V++ G DTKLMQNS + KR
Sbjct: 208 LDKFSGTLYWK-ENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKR 266
Query: 307 SNVEKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSDNFGY----N 362
++++++ N +L +FG L+ M ++ + G W G + D D+ + +
Sbjct: 267 TSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGFLS 326
Query: 363 LLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELGQV 422
++II+ N ++PISL V Y+ + T ++R S G +
Sbjct: 327 FWSYIIILNTVVPISLYVR-------------------YVPSLTWGLSRESG-----GPI 362
Query: 423 KYLFSDKTGTLTCNIMNFKKCSI 445
+ FS K +L N + C++
Sbjct: 363 ELFFSMKMKSLRSNEKSSSSCTV 385
>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
sapiens]
Length = 1170
Score = 115 bits (287), Expect = 3e-25
Identities = 180/783 (22%), Positives = 305/783 (38%), Gaps = 153/783 (19%)
Query: 151 KKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGE 210
++K ++RNG + E+ VGDI +V G LPAD +L+ ++ + ++ ++L GE
Sbjct: 187 EQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLK----IDESSLTGE 242
Query: 211 TNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNLNLDGKSLVALGPD--- 267
++ +++ L M LSGT EG R + G + G L LG +
Sbjct: 243 SD-HVKKSLDKDP--------MLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDD 293
Query: 268 ----------QILLRGTQLRNTQWVFGIVVYTGHDTKLMQN------STKAPLKRSNV-- 309
Q + TQ + + + + + N + K P K +V
Sbjct: 294 EGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQ 353
Query: 310 EKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSDNFGYNLLTFIIL 369
K+T + + + LL+ AL LY+ N+ I + + + F+
Sbjct: 354 GKLTRLAVQIGKAGLLMSALTVFILILYFVID----NFVINRRPWLPECTPIYIQYFVKF 409
Query: 370 YNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELGQVKYLFSDK 429
+ +I I++LV A+ I+ + + D + R + E +G + SDK
Sbjct: 410 F--IIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNN-LVRHLDACETMGNATAICSDK 466
Query: 430 TGTLTCNIMNFKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSCDFDDPRLLKNIED 489
TGTLT N M + I G+ Y P S D F L + D
Sbjct: 467 TGTLTMNRMTVVQAYIGGIHYRQIP------SPDVF------------------LPKVLD 502
Query: 490 RHPTAPCIQEFLTLLAVCHTVVPEKDGDNIIYQASSPDEAALVKGAKKLGFVFTARTPFS 549
I T + PEK+G + Q + E AL LGFV + +
Sbjct: 503 LIVNGISINSAYT----SKILPPEKEG-GLPRQVGNKTECAL------LGFVTDLKQDYQ 551
Query: 550 VIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFERL------- 602
+ + +E+ + V F+S RK MS ++R P+G R+Y KGA +I +
Sbjct: 552 AVRNEVPEEKLY---KVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRK 608
Query: 603 -------SKDSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKD 655
+KD M T+ +E A +GLRT+C+AY D + E + + IL +
Sbjct: 609 GEAVPFKNKDRDDMVRTV--IEPMACDGLRTICIAYRDFDDTE-----PSWDNENEILTE 661
Query: 656 RAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINI 715
L + IED ++ VP+ IA +A I + ++TGD TA I
Sbjct: 662 ---------------LTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAI 706
Query: 716 GYSCRLVSQNMALILLKEDSLDATRAAITQHCTDLGNLLGKENDVALIIDGHTLKYALSF 775
C +++ + L+ + L+ E
Sbjct: 707 ATKCGILTPGDDFLCLEG--------------KEFNRLIRNEKG---------------- 736
Query: 776 EVRRSFLDLALSCKAVICCRVSPLQK----SEIVDVVKKRVKAITLAIGDGANDVGMIQT 831
EV + LD + K + R SP K I+D + + GDG ND ++
Sbjct: 737 EVEQEKLD-KIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKK 795
Query: 832 AHVG--VGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVL 889
A VG +GI+G + + ++ F+ + K ++ G Y+ ++K + + NVV
Sbjct: 796 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM-WGRNVYDSISKFLQFQLTVNVVA 854
Query: 890 YII 892
I+
Sbjct: 855 VIV 857
>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
sapiens]
Length = 1205
Score = 115 bits (287), Expect = 3e-25
Identities = 180/783 (22%), Positives = 305/783 (38%), Gaps = 153/783 (19%)
Query: 151 KKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGE 210
++K ++RNG + E+ VGDI +V G LPAD +L+ ++ + ++ ++L GE
Sbjct: 187 EQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLK----IDESSLTGE 242
Query: 211 TNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNLNLDGKSLVALGPD--- 267
++ +++ L M LSGT EG R + G + G L LG +
Sbjct: 243 SD-HVKKSLDKDP--------MLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDD 293
Query: 268 ----------QILLRGTQLRNTQWVFGIVVYTGHDTKLMQN------STKAPLKRSNV-- 309
Q + TQ + + + + + N + K P K +V
Sbjct: 294 EGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQ 353
Query: 310 EKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSDNFGYNLLTFIIL 369
K+T + + + LL+ AL LY+ N+ I + + + F+
Sbjct: 354 GKLTRLAVQIGKAGLLMSALTVFILILYFVID----NFVINRRPWLPECTPIYIQYFVKF 409
Query: 370 YNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELGQVKYLFSDK 429
+ +I I++LV A+ I+ + + D + R + E +G + SDK
Sbjct: 410 F--IIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNN-LVRHLDACETMGNATAICSDK 466
Query: 430 TGTLTCNIMNFKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSCDFDDPRLLKNIED 489
TGTLT N M + I G+ Y P S D F L + D
Sbjct: 467 TGTLTMNRMTVVQAYIGGIHYRQIP------SPDVF------------------LPKVLD 502
Query: 490 RHPTAPCIQEFLTLLAVCHTVVPEKDGDNIIYQASSPDEAALVKGAKKLGFVFTARTPFS 549
I T + PEK+G + Q + E AL LGFV + +
Sbjct: 503 LIVNGISINSAYT----SKILPPEKEG-GLPRQVGNKTECAL------LGFVTDLKQDYQ 551
Query: 550 VIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFERL------- 602
+ + +E+ + V F+S RK MS ++R P+G R+Y KGA +I +
Sbjct: 552 AVRNEVPEEKLY---KVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRK 608
Query: 603 -------SKDSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKD 655
+KD M T+ +E A +GLRT+C+AY D + E + + IL +
Sbjct: 609 GEAVPFKNKDRDDMVRTV--IEPMACDGLRTICIAYRDFDDTE-----PSWDNENEILTE 661
Query: 656 RAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINI 715
L + IED ++ VP+ IA +A I + ++TGD TA I
Sbjct: 662 ---------------LTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAI 706
Query: 716 GYSCRLVSQNMALILLKEDSLDATRAAITQHCTDLGNLLGKENDVALIIDGHTLKYALSF 775
C +++ + L+ + L+ E
Sbjct: 707 ATKCGILTPGDDFLCLEG--------------KEFNRLIRNEKG---------------- 736
Query: 776 EVRRSFLDLALSCKAVICCRVSPLQK----SEIVDVVKKRVKAITLAIGDGANDVGMIQT 831
EV + LD + K + R SP K I+D + + GDG ND ++
Sbjct: 737 EVEQEKLD-KIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKK 795
Query: 832 AHVG--VGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVL 889
A VG +GI+G + + ++ F+ + K ++ G Y+ ++K + + NVV
Sbjct: 796 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM-WGRNVYDSISKFLQFQLTVNVVA 854
Query: 890 YII 892
I+
Sbjct: 855 VIV 857
>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo
sapiens]
Length = 1198
Score = 100 bits (250), Expect = 6e-21
Identities = 176/776 (22%), Positives = 302/776 (38%), Gaps = 151/776 (19%)
Query: 151 KKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGE 210
++K V+R G I E+ VGDI +V G LPAD + + ++ + ++ ++L GE
Sbjct: 189 EQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLK----IDESSLTGE 244
Query: 211 TNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNLNLDGK--SLVALGPDQ 268
++ ++R+ + M LSGT EG R L G + G +L+ G ++
Sbjct: 245 SD-QVRKSVDKDP--------MLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEE 295
Query: 269 ILLRGTQLRNTQWVFGIVVYT-----GHDTKLMQNSTKAPLKRSNVE-KVTNVQILVLFG 322
+ + + + + G D + ++ ++S ++ K+T + + +
Sbjct: 296 EEKKDKKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKA 355
Query: 323 ILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSDNFGYNLLTFIILYNNLIPISLLVTL 382
L++ A+ LY+ N + T Y + FII VT+
Sbjct: 356 GLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIG----------VTV 405
Query: 383 EVVKYTQALFINWDTDMYYIGNDTPAMARTSNLN------EELGQVKYLFSDKTGTLTCN 436
VV + L + + Y M + +NL E +G + SDKTGTLT N
Sbjct: 406 LVVAVPEGLPLAVTISLAY---SVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTN 462
Query: 437 IMNFKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSCDFDDPRLLKNIEDRHPTAPC 496
M + + V Y P+ PSS + M LL N A
Sbjct: 463 RMTVVQAYVGDVHYKEIPD----PSSINTKTM-------------ELLIN-------AIA 498
Query: 497 IQEFLTLLAVCHTVVPEKDGDNIIYQASSPDEAALVKGAKKLGFVFTARTPFSVIIEAMG 556
I T + PEK+G + Q + E L LGFV + + + M
Sbjct: 499 INSAYTT----KILPPEKEGA-LPRQVGNKTECGL------LGFVLDLKQDYEPVRSQMP 547
Query: 557 QEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFERLSK------------ 604
+E+ + V F+S RK MS +++ P R+Y KGA ++ ++ K
Sbjct: 548 EEKLY---KVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFR 604
Query: 605 --DSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEE 662
D M + + +E A +GLRT+CVAY D + +W + IL +
Sbjct: 605 PRDRDEMVKKV--IEPMACDGLRTICVAYRDFPSSPEPDW----DNENDILNE------- 651
Query: 663 CYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLV 722
L + IED ++ VPE I +A I + ++TGD TA I C ++
Sbjct: 652 --------LTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGII 703
Query: 723 SQNMALILLKEDSLDATRAAITQHCTDLGNLLGKENDVALIIDGHTLKYALSFEVRRSFL 782
+ L+ GKE + + + E+ + +
Sbjct: 704 HPGEDFLCLE----------------------GKEFNRRIRNE--------KGEIEQERI 733
Query: 783 DLALSCKAVICCRVSPLQK----SEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVG--V 836
D + K + R SP K I+D + + GDG ND ++ A VG +
Sbjct: 734 D-KIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAM 792
Query: 837 GISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYII 892
GI+G + + ++ FS + K ++ G Y+ ++K + + NVV I+
Sbjct: 793 GIAGTDVAKEASDIILTDDNFSSIVKAVM-WGRNVYDSISKFLQFQLTVNVVAVIV 847
>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
sapiens]
Length = 1220
Score = 92.4 bits (228), Expect = 2e-18
Identities = 117/496 (23%), Positives = 191/496 (38%), Gaps = 111/496 (22%)
Query: 417 EELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSC 476
E +G + SDKTGTLT N M + + Y P PS+
Sbjct: 462 ETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPA----PSA-------------- 503
Query: 477 DFDDPRLLKNIEDRHPTAPCIQEFLTLLAVCHTVVPEKDGDNIIYQASSPDEAALVKGAK 536
L I D A I T + PEK+G + Q + E AL
Sbjct: 504 ------LTPKILDLLVHAISINSAYTT----KILPPEKEGA-LPRQVGNKTECAL----- 547
Query: 537 KLGFVFTARTPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADN 596
LGFV + F + E + +++ + V F+S RK MS ++R P G RL+ KGA
Sbjct: 548 -LGFVLDLKRDFQPVREQIPEDKLY---KVYTFNSVRKSMSTVIRMPDGGFRLFSKGASE 603
Query: 597 VIFERLS--------------KDSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEW 642
++ ++ + +D M + +E A +GLRT+C+AY D S + +W
Sbjct: 604 ILLKKCTNILNSNGELRGFRPRDRDDMVRKI--IEPMACDGLRTICIAYRDFSAGQEPDW 661
Query: 643 LKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIW 702
+ ++ D L + IED ++ VPE I +A I +
Sbjct: 662 ----DNENEVVGD---------------LTCIAVVGIEDPVRPEVPEAIRKCQRAGITVR 702
Query: 703 VLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAITQHCTDLGNLLGKENDVAL 762
++TGD TA I C ++ + L+ GKE + +
Sbjct: 703 MVTGDNINTARAIAAKCGIIQPGEDFLCLE----------------------GKEFNRRI 740
Query: 763 IIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPLQK----SEIVDVVKKRVKAITLA 818
+ E+ + LD K + R SP K I+D + +
Sbjct: 741 RNE--------KGEIEQERLDKVWP-KLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAV 791
Query: 819 IGDGANDVGMIQTAHVG--VGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVT 876
GDG ND ++ A VG +GI+G + + ++ F+ + K ++ G Y+ ++
Sbjct: 792 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM-WGRNVYDSIS 850
Query: 877 KCILYCFYKNVVLYII 892
K + + NVV I+
Sbjct: 851 KFLQFQLTVNVVAVIV 866
Score = 39.3 bits (90), Expect = 0.023
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 13/115 (11%)
Query: 151 KKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGE 210
++K V+RNG + + VGDI +V G LPAD VL+ +++ + ++ ++L GE
Sbjct: 192 EQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLK----IDESSLTGE 247
Query: 211 TNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNLNLDGKSLVALG 265
++ + +AD M LSGT EG R + G + G LG
Sbjct: 248 SD-----HVRKSADKDP----MLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLG 293
>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
sapiens]
Length = 1173
Score = 92.4 bits (228), Expect = 2e-18
Identities = 117/496 (23%), Positives = 191/496 (38%), Gaps = 111/496 (22%)
Query: 417 EELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSC 476
E +G + SDKTGTLT N M + + Y P PS+
Sbjct: 462 ETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPA----PSA-------------- 503
Query: 477 DFDDPRLLKNIEDRHPTAPCIQEFLTLLAVCHTVVPEKDGDNIIYQASSPDEAALVKGAK 536
L I D A I T + PEK+G + Q + E AL
Sbjct: 504 ------LTPKILDLLVHAISINSAYTT----KILPPEKEGA-LPRQVGNKTECAL----- 547
Query: 537 KLGFVFTARTPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADN 596
LGFV + F + E + +++ + V F+S RK MS ++R P G RL+ KGA
Sbjct: 548 -LGFVLDLKRDFQPVREQIPEDKLY---KVYTFNSVRKSMSTVIRMPDGGFRLFSKGASE 603
Query: 597 VIFERLS--------------KDSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEW 642
++ ++ + +D M + +E A +GLRT+C+AY D S + +W
Sbjct: 604 ILLKKCTNILNSNGELRGFRPRDRDDMVRKI--IEPMACDGLRTICIAYRDFSAGQEPDW 661
Query: 643 LKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIW 702
+ ++ D L + IED ++ VPE I +A I +
Sbjct: 662 ----DNENEVVGD---------------LTCIAVVGIEDPVRPEVPEAIRKCQRAGITVR 702
Query: 703 VLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAITQHCTDLGNLLGKENDVAL 762
++TGD TA I C ++ + L+ GKE + +
Sbjct: 703 MVTGDNINTARAIAAKCGIIQPGEDFLCLE----------------------GKEFNRRI 740
Query: 763 IIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPLQK----SEIVDVVKKRVKAITLA 818
+ E+ + LD K + R SP K I+D + +
Sbjct: 741 RNE--------KGEIEQERLDKVWP-KLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAV 791
Query: 819 IGDGANDVGMIQTAHVG--VGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVT 876
GDG ND ++ A VG +GI+G + + ++ F+ + K ++ G Y+ ++
Sbjct: 792 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM-WGRNVYDSIS 850
Query: 877 KCILYCFYKNVVLYII 892
K + + NVV I+
Sbjct: 851 KFLQFQLTVNVVAVIV 866
Score = 39.3 bits (90), Expect = 0.023
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 13/115 (11%)
Query: 151 KKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGE 210
++K V+RNG + + VGDI +V G LPAD VL+ +++ + ++ ++L GE
Sbjct: 192 EQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLK----IDESSLTGE 247
Query: 211 TNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNLNLDGKSLVALG 265
++ + +AD M LSGT EG R + G + G LG
Sbjct: 248 SD-----HVRKSADKDP----MLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLG 293
>gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo
sapiens]
Length = 1243
Score = 90.9 bits (224), Expect = 7e-18
Identities = 119/496 (23%), Positives = 192/496 (38%), Gaps = 111/496 (22%)
Query: 417 EELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSC 476
E +G + SDKTGTLT N M + + V Y P+ PSS + M
Sbjct: 488 ETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPD----PSSINTKTM-------- 535
Query: 477 DFDDPRLLKNIEDRHPTAPCIQEFLTLLAVCHTVVPEKDGDNIIYQASSPDEAALVKGAK 536
LL N A I T + PEK+G + Q + E L
Sbjct: 536 -----ELLIN-------AIAINSAYTT----KILPPEKEGA-LPRQVGNKTECGL----- 573
Query: 537 KLGFVFTARTPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADN 596
LGFV + + + M +E+ + V F+S RK MS +++ P R+Y KGA
Sbjct: 574 -LGFVLDLKQDYEPVRSQMPEEKLY---KVYTFNSVRKSMSTVIKLPDESFRMYSKGASE 629
Query: 597 VIFERLSK--------------DSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEW 642
++ ++ K D M + + +E A +GLRT+CVAY D + +W
Sbjct: 630 IVLKKCCKILNGAGEPRVFRPRDRDEMVKKV--IEPMACDGLRTICVAYRDFPSSPEPDW 687
Query: 643 LKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIW 702
+ IL + L + IED ++ VPE I +A I +
Sbjct: 688 ----DNENDILNE---------------LTCICVVGIEDPVRPEVPEAIRKCQRAGITVR 728
Query: 703 VLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAITQHCTDLGNLLGKENDVAL 762
++TGD TA I C ++ + L+ GKE + +
Sbjct: 729 MVTGDNINTARAIAIKCGIIHPGEDFLCLE----------------------GKEFNRRI 766
Query: 763 IIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPLQK----SEIVDVVKKRVKAITLA 818
+ E+ + +D + K + R SP K I+D + +
Sbjct: 767 RNE--------KGEIEQERID-KIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAV 817
Query: 819 IGDGANDVGMIQTAHVG--VGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVT 876
GDG ND ++ A VG +GI+G + + ++ FS + K ++ G Y+ ++
Sbjct: 818 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVM-WGRNVYDSIS 876
Query: 877 KCILYCFYKNVVLYII 892
K + + NVV I+
Sbjct: 877 KFLQFQLTVNVVAVIV 892
Score = 37.7 bits (86), Expect = 0.066
Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 13/115 (11%)
Query: 151 KKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGE 210
++K V+R G I E+ VGDI +V G LPAD + + ++ + ++ ++L GE
Sbjct: 189 EQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLK----IDESSLTGE 244
Query: 211 TNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNLNLDGKSLVALG 265
++ ++R+ + M LSGT EG R L G + G LG
Sbjct: 245 SD-QVRKSVDKDP--------MLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLG 290
>gi|66932949 ATPase type 13A4 [Homo sapiens]
Length = 1196
Score = 87.4 bits (215), Expect = 7e-17
Identities = 81/301 (26%), Positives = 143/301 (47%), Gaps = 37/301 (12%)
Query: 563 ILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFERLSKDSKYMEETLCHLEYFATE 622
IL+ FSS +RM+VIV+ G + KGA + ++ + L+ + T+
Sbjct: 595 ILHQFPFSSALQRMTVIVQEMGGDRLAFMKGAPERVASFCQPET-VPTSFVSELQIYTTQ 653
Query: 623 GLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAIEDR 682
G R + +AY L EN++ A+T+ + E +E +L+ LG +E+R
Sbjct: 654 GFRVIALAYKKL-ENDHH--------ATTLTR----------ETVESDLIFLGLLILENR 694
Query: 683 LQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLK-EDSLDATRA 741
L+ + L+ A I+ ++TGD +TAI + +VS++ +IL++ ++ ++ A
Sbjct: 695 LKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSA 754
Query: 742 AITQHCTDLGN--LLGKENDVALIIDGHTLK-------YAL---SFEVRRSFLDLALS-- 787
+I+ + + G +++ I D + K +AL SF V L
Sbjct: 755 SISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREGSYHFALTGKSFHVISQHFSSLLPKI 814
Query: 788 -CKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQA 846
I R+SP QKS +V+ +K + + GDGAND G ++ AHVG+ +S E A
Sbjct: 815 LINGTIFARMSPGQKSSLVEEFQKLDYFVGMC-GDGANDCGALKMAHVGISLSEQEASVA 873
Query: 847 T 847
+
Sbjct: 874 S 874
>gi|148839292 ATPase type 13A3 [Homo sapiens]
Length = 1226
Score = 77.4 bits (189), Expect = 7e-14
Identities = 91/357 (25%), Positives = 145/357 (40%), Gaps = 46/357 (12%)
Query: 562 GILNVLEFSSDRKRMSVIVRTPSGR-LRLYCKGADNVIFERLSKDSKYMEETLCHLEYFA 620
GI+ FSS +RMSV+ R R + Y KGA I L K + LE F
Sbjct: 621 GIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAI-AGLCKPETVPVDFQNVLEDFT 679
Query: 621 TEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAIE 680
+G R + +A+ L W KV I +D IE N+ +G ++
Sbjct: 680 KQGFRVIALAHRKLESKL--TWHKV----QNISRDA----------IENNMDFMGLIIMQ 723
Query: 681 DRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLV-SQNMALILLKEDSLDAT 739
++L+ P + L KA I+ ++TGD TA+++ C ++ Q+ +I D
Sbjct: 724 NKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPPKDGK 783
Query: 740 RAAITQH-------CTDLGNLLGKENDVALIIDG---------HTLKYALSFEV-RRSFL 782
A I H C+ + + V L+ D H SF V F
Sbjct: 784 VAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVILEHFQ 843
Query: 783 DLA--LSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISG 840
DL L + R++P QK+++++ + + V GDGAND G ++ AH G+ +S
Sbjct: 844 DLVPKLMLHGTVFARMAPDQKTQLIEAL-QNVDYFVGMCGDGANDCGALKRAHGGISLSE 902
Query: 841 NEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFA 897
E A+ + S + V R +C +K + LY I +F+
Sbjct: 903 LEASVASPFT-------SKTPSISCVPNLIREGRAALITSFCVFKFMALYSIIQYFS 952
>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
sapiens]
Length = 1176
Score = 73.6 bits (179), Expect = 1e-12
Identities = 106/497 (21%), Positives = 181/497 (36%), Gaps = 112/497 (22%)
Query: 417 EELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSC 476
E +G + SDKTGTLT N M + I Y PE P
Sbjct: 464 ETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVPEPEAIP---------------- 507
Query: 477 DFDDPRLLKNIEDRHPTAPCIQEFLTLLAVCHTVVPEKDGDNIIYQASSPDEAALVKGAK 536
P +L + + A ++P + + + E AL
Sbjct: 508 ----PNILSYL---------VTGISVNCAYTSKILPPEKEGGLPRHVGNKTECAL----- 549
Query: 537 KLGFVFTARTPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADN 596
LG + + + + + +E + V F+S RK MS +++ G R++ KGA
Sbjct: 550 -LGLLLDLKRDYQDVRNEIPEEALY---KVYTFNSVRKSMSTVLKNSDGSYRIFSKGASE 605
Query: 597 VIFERLSK--------------DSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYE-E 641
+I ++ K D + +T+ +E A+EGLRT+C+A+ D E E E
Sbjct: 606 IILKKCFKILSANGEAKVFRPRDRDDIVKTV--IEPMASEGLRTICLAFRDFPAGEPEPE 663
Query: 642 WLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKI 701
W + I L + IED ++ VP+ I +A I +
Sbjct: 664 W-------------------DNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITV 704
Query: 702 WVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAITQHCTDLGNLLGKENDVA 761
++TGD TA I C ++ + L+ D + E
Sbjct: 705 RMVTGDNINTARAIATKCGILHPGEDFLCLEG--------------KDFNRRIRNEKG-- 748
Query: 762 LIIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPLQK----SEIVDVVKKRVKAITL 817
E+ + +D + K + R SP K I+D + +
Sbjct: 749 --------------EIEQERID-KIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVA 793
Query: 818 AIGDGANDVGMIQTAHVG--VGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRV 875
GDG ND ++ A VG +GI+G + + ++ F+ + K ++ G Y+ +
Sbjct: 794 VTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM-WGRNVYDSI 852
Query: 876 TKCILYCFYKNVVLYII 892
+K + + NVV I+
Sbjct: 853 SKFLQFQLTVNVVAVIV 869
Score = 38.5 bits (88), Expect = 0.038
Identities = 32/115 (27%), Positives = 54/115 (46%), Gaps = 13/115 (11%)
Query: 151 KKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGE 210
++K V+R G I ++ VGDI +V G LPAD +L+ ++ + ++ ++L GE
Sbjct: 191 EQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLK----IDESSLTGE 246
Query: 211 TNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNLNLDGKSLVALG 265
++ H ++ L+ LSGT EG R + G + G LG
Sbjct: 247 SD--------HVKKSLDKDPLL-LSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLG 292
>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
sapiens]
Length = 1220
Score = 73.6 bits (179), Expect = 1e-12
Identities = 106/497 (21%), Positives = 181/497 (36%), Gaps = 112/497 (22%)
Query: 417 EELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSC 476
E +G + SDKTGTLT N M + I Y PE P
Sbjct: 464 ETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVPEPEAIP---------------- 507
Query: 477 DFDDPRLLKNIEDRHPTAPCIQEFLTLLAVCHTVVPEKDGDNIIYQASSPDEAALVKGAK 536
P +L + + A ++P + + + E AL
Sbjct: 508 ----PNILSYL---------VTGISVNCAYTSKILPPEKEGGLPRHVGNKTECAL----- 549
Query: 537 KLGFVFTARTPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADN 596
LG + + + + + +E + V F+S RK MS +++ G R++ KGA
Sbjct: 550 -LGLLLDLKRDYQDVRNEIPEEALY---KVYTFNSVRKSMSTVLKNSDGSYRIFSKGASE 605
Query: 597 VIFERLSK--------------DSKYMEETLCHLEYFATEGLRTLCVAYADLSENEYE-E 641
+I ++ K D + +T+ +E A+EGLRT+C+A+ D E E E
Sbjct: 606 IILKKCFKILSANGEAKVFRPRDRDDIVKTV--IEPMASEGLRTICLAFRDFPAGEPEPE 663
Query: 642 WLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKI 701
W + I L + IED ++ VP+ I +A I +
Sbjct: 664 W-------------------DNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITV 704
Query: 702 WVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAITQHCTDLGNLLGKENDVA 761
++TGD TA I C ++ + L+ D + E
Sbjct: 705 RMVTGDNINTARAIATKCGILHPGEDFLCLEG--------------KDFNRRIRNEKG-- 748
Query: 762 LIIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPLQK----SEIVDVVKKRVKAITL 817
E+ + +D + K + R SP K I+D + +
Sbjct: 749 --------------EIEQERID-KIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVA 793
Query: 818 AIGDGANDVGMIQTAHVG--VGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRV 875
GDG ND ++ A VG +GI+G + + ++ F+ + K ++ G Y+ +
Sbjct: 794 VTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM-WGRNVYDSI 852
Query: 876 TKCILYCFYKNVVLYII 892
+K + + NVV I+
Sbjct: 853 SKFLQFQLTVNVVAVIV 869
Score = 38.5 bits (88), Expect = 0.038
Identities = 32/115 (27%), Positives = 54/115 (46%), Gaps = 13/115 (11%)
Query: 151 KKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGE 210
++K V+R G I ++ VGDI +V G LPAD +L+ ++ + ++ ++L GE
Sbjct: 191 EQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLK----IDESSLTGE 246
Query: 211 TNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNLNLDGKSLVALG 265
++ H ++ L+ LSGT EG R + G + G LG
Sbjct: 247 SD--------HVKKSLDKDPLL-LSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLG 292
>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo
sapiens]
Length = 1023
Score = 69.3 bits (168), Expect = 2e-11
Identities = 166/737 (22%), Positives = 279/737 (37%), Gaps = 181/737 (24%)
Query: 135 EIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSS 194
+I+E FK A +V+RNG +I +EV VGD+V+V G +PAD+ ++S++
Sbjct: 156 KIMESFKNMVPQQA------LVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISAN 209
Query: 195 EPQAMCYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNL 254
C V+ ++L GE+ + QTR DFT
Sbjct: 210 G----CKVDNSSLTGES------------EPQTRSP------------------DFTNEN 235
Query: 255 NLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAP-LKRSNVEKVT 313
L+ +++ + + GT GIVVYTG T + + +T A L+
Sbjct: 236 PLETRNIAFFSTNCV--EGTAR-------GIVVYTGDRTVMGRIATLASGLEGGQTPIAA 286
Query: 314 NVQ--ILVLFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSDNFGYNLLTFIILYN 371
++ I ++ G+ + + + + +L+ I+ Y
Sbjct: 287 EIEHFIHIITGVAVFLGV------------------------------SFFILSLILEYT 316
Query: 372 NLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTS----NLN--EELGQVKYL 425
L + L+ + V + L T + MAR + NL E LG +
Sbjct: 317 WLEAVIFLIGIIVANVPEGLLA---TVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTI 373
Query: 426 FSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSCDFDDPRLLK 485
SDKTGTLT N M V + F E + + FD
Sbjct: 374 CSDKTGTLTQNRMT--------VAHMWFDNQIHEADTTEN-------QSGVSFDK----- 413
Query: 486 NIEDRHPTAPCIQEFLTLLAVCHTVVPEKDGDN--IIYQASSPD--EAALVKGAKKL-GF 540
T+ + +C+ V + + +N I+ +A + D E+AL+K + G
Sbjct: 414 -------TSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGS 466
Query: 541 VFTARTPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSG---RLRLYCKGADNV 597
V R ++ I+E + F+S K I + P+ + L KGA
Sbjct: 467 VKEMRERYAKIVE-------------IPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPER 513
Query: 598 IFERLS------KDSKYMEETLCHLE--YFATEGL--RTLCVAYADLSENEYEEWLKVYQ 647
I +R S K+ EE + Y GL R L + L + ++ E +
Sbjct: 514 ILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDT 573
Query: 648 EASTILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGD 707
+ D NL +G ++ D +A VP+ + A IK+ ++TGD
Sbjct: 574 DDVNFPID--------------NLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGD 619
Query: 708 KQETAINIGYSCRLVSQNMALILLKEDSLDATRAAITQHCTDLGNLLGKENDVALIIDGH 767
TA I ++S+ + ED ++Q + + A ++ G
Sbjct: 620 HPITAKAIAKGVGIISEGNETV---EDIAARLNIPVSQ--------VNPRDAKACVVHGS 668
Query: 768 TLKYALSFEVRRSFLDLALSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVG 827
LK S ++ D+ ++ R SP QK IV+ +R AI GDG ND
Sbjct: 669 DLKDMTSEQLD----DILKYHTEIVFARTSPQQKLIIVEGC-QRQGAIVAVTGDGVNDSP 723
Query: 828 MIQTAHVGV--GISGNE 842
++ A +GV GI+G++
Sbjct: 724 ALKKADIGVAMGIAGSD 740
>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo
sapiens]
Length = 992
Score = 69.3 bits (168), Expect = 2e-11
Identities = 166/737 (22%), Positives = 279/737 (37%), Gaps = 181/737 (24%)
Query: 135 EIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSS 194
+I+E FK A +V+RNG +I +EV VGD+V+V G +PAD+ ++S++
Sbjct: 125 KIMESFKNMVPQQA------LVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISAN 178
Query: 195 EPQAMCYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNL 254
C V+ ++L GE+ + QTR DFT
Sbjct: 179 G----CKVDNSSLTGES------------EPQTRSP------------------DFTNEN 204
Query: 255 NLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAP-LKRSNVEKVT 313
L+ +++ + + GT GIVVYTG T + + +T A L+
Sbjct: 205 PLETRNIAFFSTNCV--EGTAR-------GIVVYTGDRTVMGRIATLASGLEGGQTPIAA 255
Query: 314 NVQ--ILVLFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSDNFGYNLLTFIILYN 371
++ I ++ G+ + + + + +L+ I+ Y
Sbjct: 256 EIEHFIHIITGVAVFLGV------------------------------SFFILSLILEYT 285
Query: 372 NLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTS----NLN--EELGQVKYL 425
L + L+ + V + L T + MAR + NL E LG +
Sbjct: 286 WLEAVIFLIGIIVANVPEGLLA---TVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTI 342
Query: 426 FSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSCDFDDPRLLK 485
SDKTGTLT N M V + F E + + FD
Sbjct: 343 CSDKTGTLTQNRMT--------VAHMWFDNQIHEADTTEN-------QSGVSFDK----- 382
Query: 486 NIEDRHPTAPCIQEFLTLLAVCHTVVPEKDGDN--IIYQASSPD--EAALVKGAKKL-GF 540
T+ + +C+ V + + +N I+ +A + D E+AL+K + G
Sbjct: 383 -------TSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGS 435
Query: 541 VFTARTPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSG---RLRLYCKGADNV 597
V R ++ I+E + F+S K I + P+ + L KGA
Sbjct: 436 VKEMRERYAKIVE-------------IPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPER 482
Query: 598 IFERLS------KDSKYMEETLCHLE--YFATEGL--RTLCVAYADLSENEYEEWLKVYQ 647
I +R S K+ EE + Y GL R L + L + ++ E +
Sbjct: 483 ILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDT 542
Query: 648 EASTILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGD 707
+ D NL +G ++ D +A VP+ + A IK+ ++TGD
Sbjct: 543 DDVNFPID--------------NLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGD 588
Query: 708 KQETAINIGYSCRLVSQNMALILLKEDSLDATRAAITQHCTDLGNLLGKENDVALIIDGH 767
TA I ++S+ + ED ++Q + + A ++ G
Sbjct: 589 HPITAKAIAKGVGIISEGNETV---EDIAARLNIPVSQ--------VNPRDAKACVVHGS 637
Query: 768 TLKYALSFEVRRSFLDLALSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVG 827
LK S ++ D+ ++ R SP QK IV+ +R AI GDG ND
Sbjct: 638 DLKDMTSEQLD----DILKYHTEIVFARTSPQQKLIIVEGC-QRQGAIVAVTGDGVNDSP 692
Query: 828 MIQTAHVGV--GISGNE 842
++ A +GV GI+G++
Sbjct: 693 ALKKADIGVAMGIAGSD 709
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,316,548
Number of Sequences: 37866
Number of extensions: 1835058
Number of successful extensions: 4309
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 4001
Number of HSP's gapped (non-prelim): 193
length of query: 1188
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1075
effective length of database: 13,968,660
effective search space: 15016309500
effective search space used: 15016309500
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.