Guide to the Human Genome
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Search of human proteins with 239745058

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo
sapiens]
         (544 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo ...  1099   0.0  
gi|52856430 protein expressed in prostate, ovary, testis, and pl...  1071   0.0  
gi|239747116 PREDICTED: hypothetical protein XP_002343915 isofor...  1045   0.0  
gi|153792284 pote protein [Homo sapiens]                             1035   0.0  
gi|239747114 PREDICTED: hypothetical protein XP_002343914 isofor...  1033   0.0  
gi|212549546 ANKRD26-like family B, member 2 [Homo sapiens]           970   0.0  
gi|239741769 PREDICTED: similar to protein expressed in prostate...   926   0.0  
gi|239747898 PREDICTED: actin, beta-like 3 [Homo sapiens]             920   0.0  
gi|239753333 PREDICTED: actin, beta-like 3 [Homo sapiens]             917   0.0  
gi|239741786 PREDICTED: kappa-actin [Homo sapiens]                    916   0.0  
gi|52856434 POTE ankyrin domain family, member G [Homo sapiens]       837   0.0  
gi|224282147 prostate-specific P704P [Homo sapiens]                   832   0.0  
gi|209977003 ANKRD26-like family C, member 3 [Homo sapiens]           830   0.0  
gi|113413200 PREDICTED: similar to protein expressed in prostate...   808   0.0  
gi|88953571 PREDICTED: similar to protein expressed in prostate,...   793   0.0  
gi|153791352 prostate, ovary, testis expressed protein on chromo...   791   0.0  
gi|134133226 protein expressed in prostate, ovary, testis, and p...   791   0.0  
gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo...   629   e-180
gi|50897294 POTE ankyrin domain family, member A isoform 1 [Homo...   540   e-153
gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo...   303   3e-82
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]       301   8e-82
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo...   301   8e-82
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap...   253   3e-67
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap...   253   3e-67
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa...   253   4e-67
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa...   253   4e-67
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]      249   6e-66
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]      249   6e-66
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]      248   1e-65
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ...   244   2e-64

>gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo
           sapiens]
          Length = 544

 Score = 1099 bits (2842), Expect = 0.0
 Identities = 544/544 (100%), Positives = 544/544 (100%)

Query: 1   MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGTSNVGTSGDHDDSFMKTLRSK 60
           MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGTSNVGTSGDHDDSFMKTLRSK
Sbjct: 1   MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGTSNVGTSGDHDDSFMKTLRSK 60

Query: 61  MGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDL 120
           MGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDL
Sbjct: 61  MGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDL 120

Query: 121 IVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQ 180
           IVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQ
Sbjct: 121 IVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQ 180

Query: 181 EDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLL 240
           EDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLL
Sbjct: 181 EDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLL 240

Query: 241 LGVHEQKQEVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLS 300
           LGVHEQKQEVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLS
Sbjct: 241 LGVHEQKQEVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLS 300

Query: 301 GQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQ 360
           GQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQ
Sbjct: 301 GQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQ 360

Query: 361 PEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPEN 420
           PEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPEN
Sbjct: 361 PEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPEN 420

Query: 421 QQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSELSLSHK 480
           QQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSELSLSHK
Sbjct: 421 QQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSELSLSHK 480

Query: 481 KEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILEEIESVKEKLLKTIQLNEEALT 540
           KEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILEEIESVKEKLLKTIQLNEEALT
Sbjct: 481 KEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILEEIESVKEKLLKTIQLNEEALT 540

Query: 541 KTSI 544
           KTSI
Sbjct: 541 KTSI 544


>gi|52856430 protein expressed in prostate, ovary, testis, and
           placenta 15 [Homo sapiens]
          Length = 581

 Score = 1072 bits (2771), Expect = 0.0
 Identities = 539/581 (92%), Positives = 542/581 (93%), Gaps = 37/581 (6%)

Query: 1   MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSG--------------------- 39
           MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSG                     
Sbjct: 1   MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGKSNMGTSGDHDDSFMKTLRSK 60

Query: 40  ----------------TSNVGTSGDHDDSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTW 83
                           TSNVGTSGDHD+SFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTW
Sbjct: 61  MGKCCHHCFPCCRGSGTSNVGTSGDHDNSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTW 120

Query: 84  GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLA 143
           GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLA
Sbjct: 121 GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLA 180

Query: 144 SANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGN 203
           SANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGN
Sbjct: 181 SANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGN 240

Query: 204 TALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNA 263
           TALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQ+VVKFLIKKKANLNA
Sbjct: 241 TALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNA 300

Query: 264 LDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDY 323
           LDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDY
Sbjct: 301 LDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDY 360

Query: 324 KEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIK 383
           KEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIK
Sbjct: 361 KEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIK 420

Query: 384 KHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQL 443
           KHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQL
Sbjct: 421 KHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQL 480

Query: 444 SEEQNTGISQDEILTNKQKQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAKLRLEL 503
           SEEQNTGISQDEILTNKQKQIEVAEKEMNS+LSLSHKKEEDLLRENSMLREEIA LRLEL
Sbjct: 481 SEEQNTGISQDEILTNKQKQIEVAEKEMNSKLSLSHKKEEDLLRENSMLREEIAMLRLEL 540

Query: 504 DETKHQNQLRENKILEEIESVKEKLLKTIQLNEEALTKTSI 544
           DETKHQNQLRENKILEEIESVKEKLLK IQLNEEALTKTSI
Sbjct: 541 DETKHQNQLRENKILEEIESVKEKLLKAIQLNEEALTKTSI 581


>gi|239747116 PREDICTED: hypothetical protein XP_002343915 isoform 2
           [Homo sapiens]
          Length = 551

 Score = 1045 bits (2703), Expect = 0.0
 Identities = 519/551 (94%), Positives = 532/551 (96%), Gaps = 7/551 (1%)

Query: 1   MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGTSNVGTSGDHDDSFMKTLRSK 60
           MVAEVCSMP AS VKKPFDLRSKMGKWCHHRFPCCRGSG SN+GTSGDHDDSFMK LRSK
Sbjct: 1   MVAEVCSMPTASTVKKPFDLRSKMGKWCHHRFPCCRGSGKSNMGTSGDHDDSFMKMLRSK 60

Query: 61  MG----KWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVP 116
           MG    KWCCHCFPCCRGS KSNVG WGDYD SAFMEPRYHVRREDLDKLHRAAWWGKVP
Sbjct: 61  MGNKMGKWCCHCFPCCRGSSKSNVGAWGDYDHSAFMEPRYHVRREDLDKLHRAAWWGKVP 120

Query: 117 RKDLIVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKA 176
           RKDLIVMLRDTDMNKRDK+KRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKA
Sbjct: 121 RKDLIVMLRDTDMNKRDKEKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKA 180

Query: 177 VQCQEDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGL 236
           +QCQEDECVLMLLEHGAD NI DEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGL
Sbjct: 181 IQCQEDECVLMLLEHGADRNIPDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGL 240

Query: 237 TPLLLGVHEQKQEVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSS 296
           TPLLLGVHEQKQ+VVKFLIKKKANLN LDRYGRTALILAVCCGSASIVNLLLEQNVDVSS
Sbjct: 241 TPLLLGVHEQKQQVVKFLIKKKANLNVLDRYGRTALILAVCCGSASIVNLLLEQNVDVSS 300

Query: 297 QDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVS 356
           QDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVS
Sbjct: 301 QDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVS 360

Query: 357 ENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRKSR 416
           ENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQR+SR
Sbjct: 361 ENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRRSR 420

Query: 417 KPENQQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSELS 476
           KPENQQFPDTENEEYHSDEQNDT+KQLSEEQNTGISQDEILTNKQKQIEVAE++MNSELS
Sbjct: 421 KPENQQFPDTENEEYHSDEQNDTRKQLSEEQNTGISQDEILTNKQKQIEVAEQKMNSELS 480

Query: 477 LSHKKEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILEEIESVKE---KLLKTIQ 533
           LSHKKEEDLLRENS+L+EEIA LRLELDETKHQNQLRENKILEEIESVKE   KLL+ +Q
Sbjct: 481 LSHKKEEDLLRENSVLQEEIAVLRLELDETKHQNQLRENKILEEIESVKEKTDKLLRAMQ 540

Query: 534 LNEEALTKTSI 544
           LNEEALTKT+I
Sbjct: 541 LNEEALTKTNI 551


>gi|153792284 pote protein [Homo sapiens]
          Length = 584

 Score = 1035 bits (2676), Expect = 0.0
 Identities = 519/584 (88%), Positives = 533/584 (91%), Gaps = 40/584 (6%)

Query: 1   MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGTSNVGTSGDHDDSFMKTLRSK 60
           MVAEVCSMP AS VKKPFDLRSKMGKWCHHRFPCCRGSG SN+GTSGDHDDSFMK LRSK
Sbjct: 1   MVAEVCSMPTASTVKKPFDLRSKMGKWCHHRFPCCRGSGKSNMGTSGDHDDSFMKMLRSK 60

Query: 61  MGK-------------------------------------WCCHCFPCCRGSGKSNVGTW 83
           MGK                                     WCCHCFPCCRGSGKSNVG W
Sbjct: 61  MGKCCRHCFPCCRGSGTSNVGTSGDHENSFMKMLRSKMGKWCCHCFPCCRGSGKSNVGAW 120

Query: 84  GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLA 143
           GDYD SAFMEPRYH+RREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDK+KRTALHLA
Sbjct: 121 GDYDHSAFMEPRYHIRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEKRTALHLA 180

Query: 144 SANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGN 203
           SANGNSEVVQLLLDRRCQLNVLDNKKRTALIKA+QCQEDECVLMLLEHGAD NI DEYGN
Sbjct: 181 SANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAIQCQEDECVLMLLEHGADRNIPDEYGN 240

Query: 204 TALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNA 263
           TALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQ+VVKFLIKKKANLN 
Sbjct: 241 TALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNV 300

Query: 264 LDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDY 323
           LDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDY
Sbjct: 301 LDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDY 360

Query: 324 KEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIK 383
           KEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIK
Sbjct: 361 KEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIK 420

Query: 384 KHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQL 443
           KHGSNPVGLPENLTNGASAGNGDDGLIPQR+SRKPENQQFPDTENEEYHSDEQNDT+KQL
Sbjct: 421 KHGSNPVGLPENLTNGASAGNGDDGLIPQRRSRKPENQQFPDTENEEYHSDEQNDTRKQL 480

Query: 444 SEEQNTGISQDEILTNKQKQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAKLRLEL 503
           SEEQNTGISQDEILTNKQKQIEVAE++MNSELSLSHKKEEDLLRENS+L+EEIA LRLEL
Sbjct: 481 SEEQNTGISQDEILTNKQKQIEVAEQKMNSELSLSHKKEEDLLRENSVLQEEIAMLRLEL 540

Query: 504 DETKHQNQLRENKILEEIESVKE---KLLKTIQLNEEALTKTSI 544
           DETKHQNQLRENKILEEIESVKE   KLL+ +QLNEEALTKT+I
Sbjct: 541 DETKHQNQLRENKILEEIESVKEKTDKLLRAMQLNEEALTKTNI 584


>gi|239747114 PREDICTED: hypothetical protein XP_002343914 isoform 1
           [Homo sapiens]
          Length = 584

 Score = 1033 bits (2670), Expect = 0.0
 Identities = 519/584 (88%), Positives = 532/584 (91%), Gaps = 40/584 (6%)

Query: 1   MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGTSNVGTSGDHDDSFMKTLRSK 60
           MVAEVCSMP AS VKKPFDLRSKMGKWCHHRFPCCRGSG SN+GTSGDHDDSFMK LRSK
Sbjct: 1   MVAEVCSMPTASTVKKPFDLRSKMGKWCHHRFPCCRGSGKSNMGTSGDHDDSFMKMLRSK 60

Query: 61  MGK-------------------------------------WCCHCFPCCRGSGKSNVGTW 83
           MGK                                     WCCHCFPCCRGS KSNVG W
Sbjct: 61  MGKCCRHCFPCCRGSGTSNVGTSGDHENSFMKMLRSKMGKWCCHCFPCCRGSSKSNVGAW 120

Query: 84  GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLA 143
           GDYD SAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDK+KRTALHLA
Sbjct: 121 GDYDHSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEKRTALHLA 180

Query: 144 SANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGN 203
           SANGNSEVVQLLLDRRCQLNVLDNKKRTALIKA+QCQEDECVLMLLEHGAD NI DEYGN
Sbjct: 181 SANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAIQCQEDECVLMLLEHGADRNIPDEYGN 240

Query: 204 TALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNA 263
           TALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQ+VVKFLIKKKANLN 
Sbjct: 241 TALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNV 300

Query: 264 LDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDY 323
           LDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDY
Sbjct: 301 LDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDY 360

Query: 324 KEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIK 383
           KEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIK
Sbjct: 361 KEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIK 420

Query: 384 KHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQL 443
           KHGSNPVGLPENLTNGASAGNGDDGLIPQR+SRKPENQQFPDTENEEYHSDEQNDT+KQL
Sbjct: 421 KHGSNPVGLPENLTNGASAGNGDDGLIPQRRSRKPENQQFPDTENEEYHSDEQNDTRKQL 480

Query: 444 SEEQNTGISQDEILTNKQKQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAKLRLEL 503
           SEEQNTGISQDEILTNKQKQIEVAE++MNSELSLSHKKEEDLLRENS+L+EEIA LRLEL
Sbjct: 481 SEEQNTGISQDEILTNKQKQIEVAEQKMNSELSLSHKKEEDLLRENSVLQEEIAVLRLEL 540

Query: 504 DETKHQNQLRENKILEEIESVKE---KLLKTIQLNEEALTKTSI 544
           DETKHQNQLRENKILEEIESVKE   KLL+ +QLNEEALTKT+I
Sbjct: 541 DETKHQNQLRENKILEEIESVKEKTDKLLRAMQLNEEALTKTNI 584


>gi|212549546 ANKRD26-like family B, member 2 [Homo sapiens]
          Length = 542

 Score =  970 bits (2508), Expect = 0.0
 Identities = 484/536 (90%), Positives = 492/536 (91%), Gaps = 37/536 (6%)

Query: 1   MVAEVCSMPAASAVKKPFDLRSKMGKW--------------------------------- 27
           MV EVCSMPAASAVKKPFDLRSKMGKW                                 
Sbjct: 1   MVTEVCSMPAASAVKKPFDLRSKMGKWFHHRFPCCKGSGKSNMGTSGDHDDSFMKMLRSK 60

Query: 28  ----CHHRFPCCRGSGTSNVGTSGDHDDSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTW 83
               CHH FPCCRGSGTSNVGTSGDHD+SFMKTLRSKMGKWCCHCFPCCRGSGKSNVG W
Sbjct: 61  MGKCCHHCFPCCRGSGTSNVGTSGDHDNSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGAW 120

Query: 84  GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLA 143
           GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLA
Sbjct: 121 GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLA 180

Query: 144 SANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGN 203
           SANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGAD NI DEYGN
Sbjct: 181 SANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADQNIPDEYGN 240

Query: 204 TALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNA 263
           T LHYA++NEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQ+VVKFLIKKKANLNA
Sbjct: 241 TTLHYAVHNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNA 300

Query: 264 LDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDY 323
           LDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDY
Sbjct: 301 LDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDY 360

Query: 324 KEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIK 383
           KEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIK
Sbjct: 361 KEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIK 420

Query: 384 KHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQL 443
           KHGSNPVGLPENLTNGASAGNGDDGLIPQR+SRKPENQQFPDTENEEYHSDEQNDT+KQL
Sbjct: 421 KHGSNPVGLPENLTNGASAGNGDDGLIPQRRSRKPENQQFPDTENEEYHSDEQNDTRKQL 480

Query: 444 SEEQNTGISQDEILTNKQKQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAKL 499
           SEEQNTGISQDEILTNKQKQIEVAEK+MNSELSLSHKKEEDLLRENSML+EEIA L
Sbjct: 481 SEEQNTGISQDEILTNKQKQIEVAEKKMNSELSLSHKKEEDLLRENSMLQEEIAML 536


>gi|239741769 PREDICTED: similar to protein expressed in prostate,
           ovary, testis, and placenta 2 [Homo sapiens]
          Length = 952

 Score =  926 bits (2393), Expect = 0.0
 Identities = 474/576 (82%), Positives = 495/576 (85%), Gaps = 41/576 (7%)

Query: 1   MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGTSNVGTSGD------------ 48
           MVAEV SMPAAS+VKKPF LRSKMGKWC H FPCCRGSG SNVGTSGD            
Sbjct: 1   MVAEVDSMPAASSVKKPFVLRSKMGKWCRHCFPCCRGSGKSNVGTSGDQDDSTMKTLRSK 60

Query: 49  -------------------------HDDSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTW 83
                                    HDDS MKTLRSKMGKWCCHCFPCCRGSGKSNVG W
Sbjct: 61  MGKWCCHCFPCCRGSGKSNVGTSGDHDDSAMKTLRSKMGKWCCHCFPCCRGSGKSNVGAW 120

Query: 84  GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLA 143
           GDYDDSAF+EPRYHVRREDLDKLHRAAWWGKV RKDLIVMLRDTD+NK+DKQKRTALHLA
Sbjct: 121 GDYDDSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLA 180

Query: 144 SANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGN 203
           SANGNS VV+LLLDRRCQLNVLDNKKRTAL KAVQCQEDEC LMLLEHG D NI DEYGN
Sbjct: 181 SANGNSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGN 240

Query: 204 TALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNA 263
           T LHYAIYNEDKLMAKALLLYGADIESKNK GLTPLLLGVHEQKQ+VVKFLIKKKANLNA
Sbjct: 241 TTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNA 300

Query: 264 LDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDY 323
           LDRYGRTALILAVCCGSASIV+LLLEQN+DVSSQDLSGQTAREYAVSSHHHVIC+LLSDY
Sbjct: 301 LDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDY 360

Query: 324 KEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIK 383
           KEKQMLKISSENSNPEQDLKLTSEEESQR K SENSQPEKMSQEPEINKD DREVEEE+K
Sbjct: 361 KEKQMLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMK 420

Query: 384 KHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQL 443
           KHGS  VG PENLTNGA+AGNGDDGLIP RKSR PE+QQFPDTENEEYHSDEQNDTQKQ 
Sbjct: 421 KHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQF 480

Query: 444 SEEQNTGISQDEILTNKQKQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAKLRLEL 503
            EEQNTGI  DEIL +++KQIEV EK MNSELSLS KKE+D L ENS LREEIA LRLEL
Sbjct: 481 CEEQNTGILHDEILIHEEKQIEVVEK-MNSELSLSCKKEKDFLHENSTLREEIAMLRLEL 539

Query: 504 DETKHQNQLRENKILEEIESVKEK---LLKTIQLNE 536
           D  KHQ+QLR+ K LE+IESVK+K   LLK +QLNE
Sbjct: 540 DTMKHQSQLRKKKYLEDIESVKKKNDNLLKALQLNE 575


>gi|239747898 PREDICTED: actin, beta-like 3 [Homo sapiens]
          Length = 924

 Score =  920 bits (2379), Expect = 0.0
 Identities = 466/548 (85%), Positives = 495/548 (90%), Gaps = 13/548 (2%)

Query: 1   MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGTSNVGTSGDHDDSFMKTLRSK 60
           MVAEV SMPAAS+VKKPF LRSKMGKWC H FPCCRGSG SNVGTSGDH+DS +KTL SK
Sbjct: 1   MVAEVDSMPAASSVKKPFGLRSKMGKWCCHCFPCCRGSGKSNVGTSGDHNDSSVKTLGSK 60

Query: 61  MGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDL 120
             KWCCHCFPCCRGSGKSNVG WGDYDDSAFM+PRYHV  EDLDKLHRAAWWGKVPRKDL
Sbjct: 61  RCKWCCHCFPCCRGSGKSNVGAWGDYDDSAFMDPRYHVHGEDLDKLHRAAWWGKVPRKDL 120

Query: 121 IVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQ 180
           IVMLRDTD+NKRDKQKRTALHLASANGNSEVV+L+LDRRCQLNVLDNKKRTAL KAVQCQ
Sbjct: 121 IVMLRDTDVNKRDKQKRTALHLASANGNSEVVKLVLDRRCQLNVLDNKKRTALTKAVQCQ 180

Query: 181 EDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLL 240
           EDEC LMLLEHG D NI DEYGNT LHYA+YNEDKLMAKALLLYGADIESKNK GLTPLL
Sbjct: 181 EDECALMLLEHGTDPNIPDEYGNTTLHYAVYNEDKLMAKALLLYGADIESKNKHGLTPLL 240

Query: 241 LGVHEQKQEVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLS 300
           LG+HEQKQ+VVKFLIKKKANLNALDRYGRTALILAVCCGSASIV+ LLEQNVDVSSQD  
Sbjct: 241 LGIHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSPLLEQNVDVSSQD-X 299

Query: 301 GQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQ 360
           G+TAREYAVSSHHHVIC+LLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLK SENSQ
Sbjct: 300 GKTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKGSENSQ 359

Query: 361 PEKMSQEPEINKDCDRE------VEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRK 414
           PEKMSQEPEINKD DRE      +EEE+KKHGS  VG PENLTNGA+AGNGDDGLIP RK
Sbjct: 360 PEKMSQEPEINKDGDRELEDFMAIEEEMKKHGSTHVGFPENLTNGAAAGNGDDGLIPPRK 419

Query: 415 SRKPENQQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNS- 473
           SR PE+QQFPDTENEEYHSDEQNDTQKQLSEEQNTGI QDEIL +++KQIEVAEK+MNS 
Sbjct: 420 SRTPESQQFPDTENEEYHSDEQNDTQKQLSEEQNTGILQDEILXHEEKQIEVAEKKMNSG 479

Query: 474 --ELSLSHKKEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILEEIESVKEK---L 528
              LSLS+KKE+D L ENS L+EE+A LRLELD  KHQ+QLRE K LEEIESV++K   L
Sbjct: 480 PGTLSLSYKKEKDFLHENSTLQEEVAMLRLELDIMKHQSQLREKKYLEEIESVEKKNDNL 539

Query: 529 LKTIQLNE 536
           LK +QLNE
Sbjct: 540 LKALQLNE 547


>gi|239753333 PREDICTED: actin, beta-like 3 [Homo sapiens]
          Length = 924

 Score =  917 bits (2370), Expect = 0.0
 Identities = 465/548 (84%), Positives = 494/548 (90%), Gaps = 13/548 (2%)

Query: 1   MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGTSNVGTSGDHDDSFMKTLRSK 60
           MVAEV SMPAAS+VKKPF LRSKMGKWC H FPCCRGSG SNVGTSGDH+DS +KTL SK
Sbjct: 1   MVAEVDSMPAASSVKKPFGLRSKMGKWCCHCFPCCRGSGKSNVGTSGDHNDSSVKTLGSK 60

Query: 61  MGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDL 120
             KWCCHCFPCCRGSGKSNV  WGDYDDSAFM+PRYHV  EDLDKLHRAAWWGKVPRKDL
Sbjct: 61  RCKWCCHCFPCCRGSGKSNVVAWGDYDDSAFMDPRYHVHGEDLDKLHRAAWWGKVPRKDL 120

Query: 121 IVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQ 180
           IVMLRDTD+NKRDKQKRTALHLASANGNSEVV+L+LDRRCQLNVLDNKKRTAL KAVQCQ
Sbjct: 121 IVMLRDTDVNKRDKQKRTALHLASANGNSEVVKLVLDRRCQLNVLDNKKRTALTKAVQCQ 180

Query: 181 EDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLL 240
           EDEC LMLLEHG D NI DEYGNT LHYA+YNEDKLMAKALLLYGADIESKNK GLTPLL
Sbjct: 181 EDECALMLLEHGTDPNIPDEYGNTTLHYAVYNEDKLMAKALLLYGADIESKNKHGLTPLL 240

Query: 241 LGVHEQKQEVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLS 300
           LG+HEQKQ+VVKFLIKKKANLNALDRYGRTALILAVCCGSASIV+ LLEQNVDVSSQD  
Sbjct: 241 LGIHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSPLLEQNVDVSSQD-X 299

Query: 301 GQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQ 360
           G+TAREYAVSSHHHVIC+LLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLK SENSQ
Sbjct: 300 GKTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKGSENSQ 359

Query: 361 PEKMSQEPEINKDCDRE------VEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRK 414
           PEKMSQEPEINKD DRE      +EEE+KKHGS  VG PENLTNGA+AGNGDDGLIP RK
Sbjct: 360 PEKMSQEPEINKDGDRELEDFMAIEEEMKKHGSTHVGFPENLTNGAAAGNGDDGLIPPRK 419

Query: 415 SRKPENQQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNS- 473
           SR PE+QQFPDTENEEYHSDEQNDTQKQLSEEQNTGI QDEIL +++KQIEVAEK+MNS 
Sbjct: 420 SRTPESQQFPDTENEEYHSDEQNDTQKQLSEEQNTGILQDEILXHEEKQIEVAEKKMNSG 479

Query: 474 --ELSLSHKKEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILEEIESVKEK---L 528
              LSLS+KKE+D L ENS L+EE+A LRLELD  KHQ+QLRE K LEEIESV++K   L
Sbjct: 480 PGTLSLSYKKEKDFLHENSTLQEEVAMLRLELDIMKHQSQLREKKYLEEIESVEKKNDNL 539

Query: 529 LKTIQLNE 536
           LK +QLNE
Sbjct: 540 LKALQLNE 547


>gi|239741786 PREDICTED: kappa-actin [Homo sapiens]
          Length = 924

 Score =  916 bits (2368), Expect = 0.0
 Identities = 463/548 (84%), Positives = 494/548 (90%), Gaps = 13/548 (2%)

Query: 1   MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGTSNVGTSGDHDDSFMKTLRSK 60
           MVAEV SMPAAS+VKKPF LRSKMGKWC H FPCCRGSG SNVGTSGD +DS +KTL SK
Sbjct: 1   MVAEVDSMPAASSVKKPFGLRSKMGKWCCHCFPCCRGSGKSNVGTSGDRNDSSVKTLGSK 60

Query: 61  MGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDL 120
             KWCCHCFPCCRGSGKSNVG WGDYDDSAFM+PRYHV  EDLDKLHRAAWWGKVPRKDL
Sbjct: 61  RCKWCCHCFPCCRGSGKSNVGAWGDYDDSAFMDPRYHVHGEDLDKLHRAAWWGKVPRKDL 120

Query: 121 IVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQ 180
           IVMLRDTD+NKRDKQKRTALHLASANGNSEVV+L+LDRRCQLNVLDNKKRTAL KAVQCQ
Sbjct: 121 IVMLRDTDVNKRDKQKRTALHLASANGNSEVVKLVLDRRCQLNVLDNKKRTALTKAVQCQ 180

Query: 181 EDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLL 240
           EDEC LMLLEHG D NI DEYGNT LHYA+YNEDKLMAKALLLYGADIESKNK GLTPLL
Sbjct: 181 EDECALMLLEHGTDPNIPDEYGNTTLHYAVYNEDKLMAKALLLYGADIESKNKHGLTPLL 240

Query: 241 LGVHEQKQEVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLS 300
           LG+HEQKQ+VVKFLIKKKANLNALDRYGRTALILAVCCGSA+IV+ LLEQN+DVSSQD  
Sbjct: 241 LGIHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSANIVSPLLEQNIDVSSQD-X 299

Query: 301 GQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQ 360
           GQTAREYAVSSHHHVIC+LLSDYKEKQMLKISSENSNPEQDLKLTSEEESQ+LK SENSQ
Sbjct: 300 GQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEESQKLKGSENSQ 359

Query: 361 PEKMSQEPEINKDCDRE------VEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRK 414
           PEKMSQEPEINKD DRE      +EEE+KKHGS  VG PENLTNGA+AGNGDDGLIP RK
Sbjct: 360 PEKMSQEPEINKDGDRELEDFMAIEEEMKKHGSTHVGFPENLTNGAAAGNGDDGLIPPRK 419

Query: 415 SRKPENQQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNS- 473
           SR PE+QQFPDTENEEYHSDEQNDTQKQLSEEQNTGI QDEIL +++KQIEVAEK+MNS 
Sbjct: 420 SRTPESQQFPDTENEEYHSDEQNDTQKQLSEEQNTGILQDEILXHEEKQIEVAEKKMNSG 479

Query: 474 --ELSLSHKKEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILEEIESVKEK---L 528
              LSLS+KKE+D L ENS L+EE+A LRLELD  KHQ+QLRE K LEEIESV++K   L
Sbjct: 480 PGTLSLSYKKEKDFLHENSTLQEEVAMLRLELDIMKHQSQLREKKYLEEIESVEKKNDNL 539

Query: 529 LKTIQLNE 536
           LK +QLNE
Sbjct: 540 LKALQLNE 547


>gi|52856434 POTE ankyrin domain family, member G [Homo sapiens]
          Length = 508

 Score =  837 bits (2162), Expect = 0.0
 Identities = 419/507 (82%), Positives = 441/507 (86%), Gaps = 37/507 (7%)

Query: 1   MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGTSNVGTSGDHDDSFMKTLRSK 60
           MVAE  SMPAAS+VKKPF LRSKMGKWC H FP CRGSG SNVGTSGDHDDS MKTLRSK
Sbjct: 1   MVAEAGSMPAASSVKKPFGLRSKMGKWCRHCFPWCRGSGKSNVGTSGDHDDSAMKTLRSK 60

Query: 61  MGKWC-------------------------------------CHCFPCCRGSGKSNVGTW 83
           MGKWC                                     CHCFPCCRGSGKS VG W
Sbjct: 61  MGKWCRHCFPWCRGSSKSNVGTSGDHDDSAMKTLRSKMGKWCCHCFPCCRGSGKSKVGPW 120

Query: 84  GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLA 143
           GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVML+DTDMNK+DKQKRTALHLA
Sbjct: 121 GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLA 180

Query: 144 SANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGN 203
           SANGNSEVV+LLLDRRCQLN+LDNKKRTAL KAVQC+EDEC LMLLEHG D NI DEYGN
Sbjct: 181 SANGNSEVVKLLLDRRCQLNILDNKKRTALTKAVQCREDECALMLLEHGTDPNIPDEYGN 240

Query: 204 TALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNA 263
           TALHYAIYNEDKLMAKALLLYGADIESKNK GLTPLLLGVHEQKQ+VVKFLIKKKANLNA
Sbjct: 241 TALHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNA 300

Query: 264 LDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDY 323
           LDRYGRTALILAVCCGSASIV+LLLEQN+DVSSQDLSGQTAREYAVSSHH+VIC+LLSDY
Sbjct: 301 LDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHNVICQLLSDY 360

Query: 324 KEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIK 383
           KEKQMLK+SSENSNPEQDLKLTSEEESQRLK SENSQPE+MSQEPEINK  DR+VEEE+K
Sbjct: 361 KEKQMLKVSSENSNPEQDLKLTSEEESQRLKGSENSQPEEMSQEPEINKGGDRKVEEEMK 420

Query: 384 KHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQL 443
           KHGS  +G PENL NGA+A NGDDGLIP RKSR PE+QQFPDTENE+YHSDEQNDTQKQL
Sbjct: 421 KHGSTHMGFPENLPNGATADNGDDGLIPPRKSRTPESQQFPDTENEQYHSDEQNDTQKQL 480

Query: 444 SEEQNTGISQDEILTNKQKQIEVAEKE 470
           SEEQNTGI QDEIL +++KQIEVAE E
Sbjct: 481 SEEQNTGILQDEILIHEEKQIEVAENE 507


>gi|224282147 prostate-specific P704P [Homo sapiens]
          Length = 508

 Score =  832 bits (2150), Expect = 0.0
 Identities = 417/507 (82%), Positives = 439/507 (86%), Gaps = 37/507 (7%)

Query: 1   MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGTSNVGTSGDHDDSFMKTLRSK 60
           MVAE  SMPAAS+VKKPF LRSKMGKWC H FP CRGSG SNVGTSGDHDDS MKTLRSK
Sbjct: 1   MVAEAGSMPAASSVKKPFGLRSKMGKWCRHCFPWCRGSGKSNVGTSGDHDDSAMKTLRSK 60

Query: 61  MGKWC-------------------------------------CHCFPCCRGSGKSNVGTW 83
           MGKWC                                     CHCFPCCRGSGKS VG W
Sbjct: 61  MGKWCRHCFPWCRGSGKSNVGTSGDHDDSAMKTLRSKMGKWCCHCFPCCRGSGKSKVGPW 120

Query: 84  GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLA 143
           GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVML+DTDMNK+DKQKRTALHLA
Sbjct: 121 GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLA 180

Query: 144 SANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGN 203
           SANGNSEVV+LLLDRRCQLN+LDNKKRTAL KAVQCQEDEC LMLLEHG D NI DEYGN
Sbjct: 181 SANGNSEVVKLLLDRRCQLNILDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGN 240

Query: 204 TALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNA 263
           TALHYAIYNEDKLMAKALLLYGADIESKNK GLTPLLLGVHEQKQ+VVKFLIKKKANLNA
Sbjct: 241 TALHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNA 300

Query: 264 LDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDY 323
           LDRYGRT LILAVCCGSASIV+LLLEQN+DVSSQDLSGQTAREYAVSS H+VIC+LLSDY
Sbjct: 301 LDRYGRTVLILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSRHNVICQLLSDY 360

Query: 324 KEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIK 383
           KEKQ+LK+SSENSNPEQDLKLTSEEESQRLK SENSQPE+MSQEPEINK  DR+VEEE+K
Sbjct: 361 KEKQILKVSSENSNPEQDLKLTSEEESQRLKGSENSQPEEMSQEPEINKGGDRKVEEEMK 420

Query: 384 KHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQL 443
           KHGS  +G PENL NGA+A NGDDGLIP RKSR PE+QQFPDTENE+YHSDEQNDTQKQL
Sbjct: 421 KHGSTHMGFPENLPNGATADNGDDGLIPPRKSRTPESQQFPDTENEQYHSDEQNDTQKQL 480

Query: 444 SEEQNTGISQDEILTNKQKQIEVAEKE 470
           SEEQNTGI QDEIL +++KQIEVAE E
Sbjct: 481 SEEQNTGILQDEILIHEEKQIEVAENE 507


>gi|209977003 ANKRD26-like family C, member 3 [Homo sapiens]
          Length = 545

 Score =  830 bits (2143), Expect = 0.0
 Identities = 404/451 (89%), Positives = 426/451 (94%)

Query: 20  LRSKMGKWCHHRFPCCRGSGTSNVGTSGDHDDSFMKTLRSKMGKWCCHCFPCCRGSGKSN 79
           LRSKMGKWC H FPCCRGSG SNVGTSGDHDDS MKTLRSKMGKWCCHCFPCCRGSGK+ 
Sbjct: 94  LRSKMGKWCCHCFPCCRGSGKSNVGTSGDHDDSAMKTLRSKMGKWCCHCFPCCRGSGKNK 153

Query: 80  VGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTA 139
           VG WGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVML+DTDMNK+DKQKRTA
Sbjct: 154 VGPWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTA 213

Query: 140 LHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQD 199
           LHLASANGNSEVV+LLLDRRCQLN+LDNKKRTAL KAVQCQEDEC LMLLEHG D NI D
Sbjct: 214 LHLASANGNSEVVKLLLDRRCQLNILDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPD 273

Query: 200 EYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKA 259
           EYGNTALHYAIYNEDKLMAKALLLYGADIESKNK GLTPLLLGVHEQKQ+VVKFLIKKKA
Sbjct: 274 EYGNTALHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKA 333

Query: 260 NLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICEL 319
           NLNALDRYGRTALILAVCCGSASIV+LLLEQN+DVSSQDLSGQTAREYAVSS H+VIC+L
Sbjct: 334 NLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSRHNVICQL 393

Query: 320 LSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVE 379
           LSDYKEKQ+LK+SSENSNPEQDLKLTSEEESQRLK SENSQPE+MSQEPEINK  DR+VE
Sbjct: 394 LSDYKEKQILKVSSENSNPEQDLKLTSEEESQRLKGSENSQPEEMSQEPEINKGGDRKVE 453

Query: 380 EEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDT 439
           EE+KKHGS  +G PENLTNGA+A NGDDGLIP RKSR PE+QQFPDTENE+YHSDEQNDT
Sbjct: 454 EEMKKHGSTHMGFPENLTNGATADNGDDGLIPPRKSRTPESQQFPDTENEQYHSDEQNDT 513

Query: 440 QKQLSEEQNTGISQDEILTNKQKQIEVAEKE 470
           QKQLSEEQNTGI QDEIL +++KQIEVAE E
Sbjct: 514 QKQLSEEQNTGILQDEILIHEEKQIEVAENE 544



 Score =  166 bits (421), Expect = 4e-41
 Identities = 77/90 (85%), Positives = 79/90 (87%)

Query: 1  MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGTSNVGTSGDHDDSFMKTLRSK 60
          MVAE  SMPAAS+VKKPF LRSKMGKWC H F  CRGSG SNVGTSGDHDDS MKTLRSK
Sbjct: 1  MVAEAGSMPAASSVKKPFGLRSKMGKWCRHCFAWCRGSGKSNVGTSGDHDDSAMKTLRSK 60

Query: 61 MGKWCCHCFPCCRGSGKSNVGTWGDYDDSA 90
          MGKWCCHCFP CRGSGKSNVGT GD+DDSA
Sbjct: 61 MGKWCCHCFPWCRGSGKSNVGTSGDHDDSA 90


>gi|113413200 PREDICTED: similar to protein expressed in prostate,
           ovary, testis, and placenta 2 [Homo sapiens]
          Length = 1038

 Score =  808 bits (2087), Expect = 0.0
 Identities = 409/507 (80%), Positives = 434/507 (85%), Gaps = 9/507 (1%)

Query: 1   MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGTSNVGTSGDHDDSFMKTLRSK 60
           MVAEV SMPAAS+VKKPF LRSKMGKWC H FPCCRGSG SNVGTSGD DDS MKTLRSK
Sbjct: 1   MVAEVDSMPAASSVKKPFVLRSKMGKWCRHCFPCCRGSGKSNVGTSGDQDDSTMKTLRSK 60

Query: 61  MGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDL 120
           MGKWCCHCFPCCRGSGKSNVG WGDYDDSAF+EPRYHVRREDLDKLHRAAWWGKV RKDL
Sbjct: 61  MGKWCCHCFPCCRGSGKSNVGAWGDYDDSAFVEPRYHVRREDLDKLHRAAWWGKVARKDL 120

Query: 121 IVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQ 180
           IVMLRDTD+NK+DKQKRTALHLASANGNS VV+LLLDRRCQLNVLDNKKRTAL KAVQCQ
Sbjct: 121 IVMLRDTDVNKQDKQKRTALHLASANGNSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQ 180

Query: 181 EDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLL 240
           EDEC LMLLEHG D NI DEYGNT LHYAIYNEDKLMAKALLLYGADIESKNK GLTPLL
Sbjct: 181 EDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLL 240

Query: 241 LGVHEQKQEVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLS 300
           LGVHEQKQ+VVKFLIKKKANLNALDRYGRTALILAVCCGSASIV+LLLEQN+DVSSQDLS
Sbjct: 241 LGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLS 300

Query: 301 GQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQ 360
           GQTAREYAVSSHHHVIC+LLSDYKEKQMLKISSENSNPEQDLKLTSEEESQR K SENSQ
Sbjct: 301 GQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRFKGSENSQ 360

Query: 361 PEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPEN 420
           PEKMSQEPEINKD DREVEEE+KKH SN VGL ENL+NG +AGNGDDGLIPQRKSR PEN
Sbjct: 361 PEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLSNGVTAGNGDDGLIPQRKSRTPEN 420

Query: 421 QQFPDTENEEYHS-----DEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSEL 475
           QQFPD E+EEYH       +  + Q      +N+   QD  LT++++   +   E     
Sbjct: 421 QQFPDNESEEYHRICELVSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPE 480

Query: 476 SLSHK----KEEDLLRENSMLREEIAK 498
             S +    K+ D   EN M  EE+ K
Sbjct: 481 KRSQEPEINKDGDRELENFMAIEEMKK 507



 Score =  373 bits (958), Expect = e-103
 Identities = 233/442 (52%), Positives = 277/442 (62%), Gaps = 28/442 (6%)

Query: 122 VMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQE 181
           ++L   D+  ++K   T L L       +VV+ L+ ++  LN LD   RTALI AV C  
Sbjct: 221 LLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGS 280

Query: 182 DECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGAD----IESKNKCGLT 237
              V +LLE   D + QD  G TA  YA+ +   ++ + L  Y       I S+N     
Sbjct: 281 ASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQ 340

Query: 238 PLLLGVHEQKQEVV---KFLIKKKANLNALDRYGRTALILAVCCGSASIVNLL--LEQNV 292
            L L   E+ Q          +K +    +++ G   +   +    ++ V LL  L   V
Sbjct: 341 DLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLSNGV 400

Query: 293 DVSSQDLSGQTAREYAV----------SSHHHVICELLSDYKEKQMLKISSENSNPEQDL 342
              + D      R+             S  +H ICEL+SDYKEKQM K SSENSNPEQDL
Sbjct: 401 TAGNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEKQMPKYSSENSNPEQDL 460

Query: 343 KLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVE-----EEIKKHGSNPVGLPENLT 397
           KLTSEEESQRLK SEN QPEK SQEPEINKD DRE+E     EE+KKHGS  VG PENLT
Sbjct: 461 KLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHGSTHVGFPENLT 520

Query: 398 NGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEIL 457
           NGA+AGNGDDGLIP RKSR PE+QQFPDTENEEYHSDEQNDTQKQ  EEQNTGI  DEIL
Sbjct: 521 NGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEIL 580

Query: 458 TNKQKQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKI 517
            +++KQIEV EK MNSELSLS KKE D L ENSMLREEIA LRLELD  KHQ+QLR+ K 
Sbjct: 581 IHEEKQIEVVEK-MNSELSLSCKKERDFLHENSMLREEIAMLRLELDTMKHQSQLRKKKY 639

Query: 518 LEEIESVKEK---LLKTIQLNE 536
           LE+IESVK+K   LLK +QLNE
Sbjct: 640 LEDIESVKKKNDNLLKALQLNE 661


>gi|88953571 PREDICTED: similar to protein expressed in prostate,
           ovary, testis, and placenta 2 isoform 2 [Homo sapiens]
          Length = 1075

 Score =  793 bits (2047), Expect = 0.0
 Identities = 410/544 (75%), Positives = 435/544 (79%), Gaps = 46/544 (8%)

Query: 1   MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGTSNVGTSGD------------ 48
           MVAEV SMPAAS+VKKPF LRSKMGKWC H FPCCRGSG SNVGTSGD            
Sbjct: 1   MVAEVDSMPAASSVKKPFVLRSKMGKWCRHCFPCCRGSGKSNVGTSGDQDDSTMKTLRSK 60

Query: 49  -------------------------HDDSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTW 83
                                    HDDS MKTLRSKMGKWCCHCFPCCRGSGKSNVG W
Sbjct: 61  MGKWCCHCFPCCRGSGKSNVGTSGDHDDSAMKTLRSKMGKWCCHCFPCCRGSGKSNVGAW 120

Query: 84  GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLA 143
           GDYDDSAF+EPRYHVRREDLDKLHRAAWWGKV RKDLIVMLRDTD+NK+DKQKRTALHLA
Sbjct: 121 GDYDDSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLA 180

Query: 144 SANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGN 203
           SANGNS VV+LLLDRRCQLNVLDNKKRTAL KAVQCQEDEC LMLLEHG D NI DEYGN
Sbjct: 181 SANGNSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGN 240

Query: 204 TALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNA 263
           T LHYAIYNEDKLMAKALLLYGADIESKNK GLTPLLLGVHEQKQ+VVKFLIKKKANLNA
Sbjct: 241 TTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNA 300

Query: 264 LDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDY 323
           LDRYGRTALILAVCCGSASIV+LLLEQN+DVSSQDLSGQTAREYAVSSHHHVIC+LLSDY
Sbjct: 301 LDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDY 360

Query: 324 KEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIK 383
           KEKQMLKISSENSNPEQDLKLTSEEESQR K SENSQPEKMSQEPEINKD DREVEEE+K
Sbjct: 361 KEKQMLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMK 420

Query: 384 KHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHS-----DEQND 438
           KH SN VGL ENL+NG +AGNGDDGLIPQRKSR PENQQFPD E+EEYH       +  +
Sbjct: 421 KHESNNVGLLENLSNGVTAGNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKE 480

Query: 439 TQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSELSLSHK----KEEDLLRENSMLRE 494
            Q      +N+   QD  LT++++   +   E       S +    K+ D   EN M  E
Sbjct: 481 KQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIE 540

Query: 495 EIAK 498
           E+ K
Sbjct: 541 EMKK 544



 Score =  371 bits (953), Expect = e-103
 Identities = 232/442 (52%), Positives = 277/442 (62%), Gaps = 28/442 (6%)

Query: 122 VMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQE 181
           ++L   D+  ++K   T L L       +VV+ L+ ++  LN LD   RTALI AV C  
Sbjct: 258 LLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGS 317

Query: 182 DECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGAD----IESKNKCGLT 237
              V +LLE   D + QD  G TA  YA+ +   ++ + L  Y       I S+N     
Sbjct: 318 ASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQ 377

Query: 238 PLLLGVHEQKQEVV---KFLIKKKANLNALDRYGRTALILAVCCGSASIVNLL--LEQNV 292
            L L   E+ Q          +K +    +++ G   +   +    ++ V LL  L   V
Sbjct: 378 DLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLSNGV 437

Query: 293 DVSSQDLSGQTAREYAV----------SSHHHVICELLSDYKEKQMLKISSENSNPEQDL 342
              + D      R+             S  +H ICEL+SDYKEKQM K SSENSNPEQDL
Sbjct: 438 TAGNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEKQMPKYSSENSNPEQDL 497

Query: 343 KLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVE-----EEIKKHGSNPVGLPENLT 397
           KLTSEEESQRLK SEN QPEK SQEPEINKD DRE+E     EE+KKHGS  VG PENLT
Sbjct: 498 KLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHGSTHVGFPENLT 557

Query: 398 NGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEIL 457
           NGA+AGNGDDGLIP RKSR PE+QQFPDTENEEYHSDEQNDTQKQ  EEQNTGI  DEIL
Sbjct: 558 NGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEIL 617

Query: 458 TNKQKQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKI 517
            +++KQIEV EK MNSELSLS KKE+D L ENS LREEIA LRLELD  KHQ+QLR+ K 
Sbjct: 618 IHEEKQIEVVEK-MNSELSLSCKKEKDFLHENSTLREEIAMLRLELDTMKHQSQLRKKKY 676

Query: 518 LEEIESVKEK---LLKTIQLNE 536
           LE+IESVK+K   LLK +QLNE
Sbjct: 677 LEDIESVKKKNDNLLKALQLNE 698


>gi|153791352 prostate, ovary, testis expressed protein on
           chromosome 2 [Homo sapiens]
          Length = 1075

 Score =  791 bits (2043), Expect = 0.0
 Identities = 409/546 (74%), Positives = 434/546 (79%), Gaps = 46/546 (8%)

Query: 1   MVAEVCSMPAASAVKKPFDLRSKMGKWC-------------------------------- 28
           MV EV SMPAAS+VKKPF LRSKMGKWC                                
Sbjct: 1   MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCCRESGKSNVGTSGDHDDSAMKTLRSK 60

Query: 29  -----HHRFPCCRGSGTSNVGTSGDHDDSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTW 83
                 H FPCCRGSG SNVG SGDHDDS MKTLR+KMGKWCCHCFPCCRGS KS VG W
Sbjct: 61  MGKWCRHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSSKSKVGAW 120

Query: 84  GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLA 143
           GDYDDSAFMEPRYHVR EDLDKLHRAAWWGKVPRKDLIVMLRDTD+NK+DKQKRTALHLA
Sbjct: 121 GDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKQDKQKRTALHLA 180

Query: 144 SANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGN 203
           SANGNSEVV+LLLDRRCQLNVLDNKKRTALIKAVQCQEDEC LMLLEHG D NI DEYGN
Sbjct: 181 SANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGN 240

Query: 204 TALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNA 263
           T LHYAIYNEDKLMAKALLLYGADIESKNK GLTPLLLGVHEQKQ+VVKFLIKKKANLNA
Sbjct: 241 TTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNA 300

Query: 264 LDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDY 323
           LDRYGRTALILAVCCGSASIV+LLLEQN+DVSSQDLSGQTAREYAVSSHHHVIC+LLSDY
Sbjct: 301 LDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDY 360

Query: 324 KEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIK 383
           KEKQMLKISSENSNPEQDLKLTSEEESQR K SENSQPEKMSQEPEINKD DREVEEE+K
Sbjct: 361 KEKQMLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMK 420

Query: 384 KHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHS-----DEQND 438
           KH SN VGL ENLTNG +AGNGD+GLIPQRKSR PENQQFPD E+EEYH       +  +
Sbjct: 421 KHESNNVGLLENLTNGVTAGNGDNGLIPQRKSRTPENQQFPDNESEEYHRICELLSDYKE 480

Query: 439 TQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSELSLSHK----KEEDLLRENSMLRE 494
            Q      +N+   QD  LT++++   +   E       S +    K+ D   EN M  E
Sbjct: 481 KQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIE 540

Query: 495 EIAKLR 500
           E+ K R
Sbjct: 541 EMKKHR 546



 Score =  370 bits (951), Expect = e-102
 Identities = 232/442 (52%), Positives = 277/442 (62%), Gaps = 28/442 (6%)

Query: 122 VMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQE 181
           ++L   D+  ++K   T L L       +VV+ L+ ++  LN LD   RTALI AV C  
Sbjct: 258 LLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGS 317

Query: 182 DECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGAD----IESKNKCGLT 237
              V +LLE   D + QD  G TA  YA+ +   ++ + L  Y       I S+N     
Sbjct: 318 ASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQ 377

Query: 238 PLLLGVHEQKQEVV---KFLIKKKANLNALDRYGRTALILAVCCGSASIVNLL--LEQNV 292
            L L   E+ Q          +K +    +++ G   +   +    ++ V LL  L   V
Sbjct: 378 DLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLTNGV 437

Query: 293 DVSSQDLSGQTAREYAV----------SSHHHVICELLSDYKEKQMLKISSENSNPEQDL 342
              + D      R+             S  +H ICELLSDYKEKQM K SSENSNPEQDL
Sbjct: 438 TAGNGDNGLIPQRKSRTPENQQFPDNESEEYHRICELLSDYKEKQMPKYSSENSNPEQDL 497

Query: 343 KLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVE-----EEIKKHGSNPVGLPENLT 397
           KLTSEEESQRLK SEN QPEK SQEPEINKD DRE+E     EE+KKH S  VG PENLT
Sbjct: 498 KLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHRSTHVGFPENLT 557

Query: 398 NGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEIL 457
           NGA+AGNGDDGLIP RKSR PE+QQFPDTENEEYHSDEQNDTQKQ  EEQNTGI  DEIL
Sbjct: 558 NGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEIL 617

Query: 458 TNKQKQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKI 517
            +++KQIEV EK MNSELSLS KKE+D+L ENS LREEIA LRLELD  KHQ+QLRE K 
Sbjct: 618 IHEEKQIEVVEK-MNSELSLSCKKEKDILHENSTLREEIAMLRLELDTMKHQSQLREKKY 676

Query: 518 LEEIESVKEK---LLKTIQLNE 536
           LE+IESVK++   LLK +QLNE
Sbjct: 677 LEDIESVKKRNDNLLKALQLNE 698


>gi|134133226 protein expressed in prostate, ovary, testis, and
           placenta 2 [Homo sapiens]
          Length = 1075

 Score =  791 bits (2042), Expect = 0.0
 Identities = 408/544 (75%), Positives = 434/544 (79%), Gaps = 46/544 (8%)

Query: 1   MVAEVCSMPAASAVKKPFDLRSKMGKWC-------------------------------- 28
           MV EV SMPAAS+VKKPF LRSKMGKWC                                
Sbjct: 1   MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCYRESGKSNVGTSGDHDDSAMKTLRSK 60

Query: 29  -----HHRFPCCRGSGTSNVGTSGDHDDSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTW 83
                HH FPCCRGSG SNVG SGDHDDS MKTLR+KMGKWCCHCFPCCRGSGKS VG W
Sbjct: 61  MGKWCHHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSGKSKVGAW 120

Query: 84  GDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLA 143
           GDYDDSAFMEPRYHVR EDLDKLHRAAWWGKVPRKDLIVMLRDTD+NK+DKQKRTALHLA
Sbjct: 121 GDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLA 180

Query: 144 SANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGN 203
           SANGNSEVV+LLLDRRCQLNVLDNKKRTALIKAVQCQEDEC LMLLEHG D NI DEYGN
Sbjct: 181 SANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGN 240

Query: 204 TALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNA 263
           T LHYAIYNEDKLMAKALLLYGADIESKNK GLTPLLLGVHEQKQ+VVKFLIKKKANLNA
Sbjct: 241 TTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNA 300

Query: 264 LDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDY 323
           LDRYGRTALILAVCCGSASIV+LLLEQN+DVSSQDLSGQTAREYAVSSHHHVIC+LLSDY
Sbjct: 301 LDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDY 360

Query: 324 KEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIK 383
           KEKQMLKISSENSNPEQ+LKLTSEEESQR K SENSQPEKMSQE EINKD DREVEEE+K
Sbjct: 361 KEKQMLKISSENSNPEQELKLTSEEESQRFKGSENSQPEKMSQELEINKDGDREVEEEMK 420

Query: 384 KHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHS-----DEQND 438
           KH SN VGL ENLTNG +AGNGD+GLIPQRKSR PENQQFPD E+EEYH       +  +
Sbjct: 421 KHESNNVGLLENLTNGVTAGNGDNGLIPQRKSRTPENQQFPDNESEEYHRICELLSDYKE 480

Query: 439 TQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSELSLSHK----KEEDLLRENSMLRE 494
            Q      +N+   QD  LT++++   +   E       S +    K+ D   EN M  E
Sbjct: 481 KQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIE 540

Query: 495 EIAK 498
           E+ K
Sbjct: 541 EMKK 544



 Score =  374 bits (960), Expect = e-103
 Identities = 234/442 (52%), Positives = 278/442 (62%), Gaps = 28/442 (6%)

Query: 122 VMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQE 181
           ++L   D+  ++K   T L L       +VV+ L+ ++  LN LD   RTALI AV C  
Sbjct: 258 LLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGS 317

Query: 182 DECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGAD----IESKNKCGLT 237
              V +LLE   D + QD  G TA  YA+ +   ++ + L  Y       I S+N     
Sbjct: 318 ASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQ 377

Query: 238 PLLLGVHEQKQEVV---KFLIKKKANLNALDRYGRTALILAVCCGSASIVNLL--LEQNV 292
            L L   E+ Q          +K +    +++ G   +   +    ++ V LL  L   V
Sbjct: 378 ELKLTSEEESQRFKGSENSQPEKMSQELEINKDGDREVEEEMKKHESNNVGLLENLTNGV 437

Query: 293 DVSSQDLSGQTAREYAV----------SSHHHVICELLSDYKEKQMLKISSENSNPEQDL 342
              + D      R+             S  +H ICELLSDYKEKQM K SSENSNPEQDL
Sbjct: 438 TAGNGDNGLIPQRKSRTPENQQFPDNESEEYHRICELLSDYKEKQMPKYSSENSNPEQDL 497

Query: 343 KLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVE-----EEIKKHGSNPVGLPENLT 397
           KLTSEEESQRLK SEN QPEK SQEPEINKD DRE+E     EE+KKHGS  VG PENLT
Sbjct: 498 KLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHGSTHVGFPENLT 557

Query: 398 NGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEIL 457
           NGA+AGNGDDGLIP RKSR PE+QQFPDTENEEYHSDEQNDTQKQ  EEQNTGI  DEIL
Sbjct: 558 NGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEIL 617

Query: 458 TNKQKQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKI 517
            +++KQIEV EK MNSELSLS KKE+D+L ENS LREEIA LRLELD  KHQ+QLRE K 
Sbjct: 618 IHEEKQIEVVEK-MNSELSLSCKKEKDVLHENSTLREEIAMLRLELDTMKHQSQLREKKY 676

Query: 518 LEEIESVKEK---LLKTIQLNE 536
           LE+IESVK+K   LLK +QLNE
Sbjct: 677 LEDIESVKKKNDNLLKALQLNE 698


>gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo
           sapiens]
          Length = 498

 Score =  629 bits (1623), Expect = e-180
 Identities = 331/520 (63%), Positives = 386/520 (74%), Gaps = 51/520 (9%)

Query: 1   MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGTSNVGTSGDHDDSFMKTLRSK 60
           MVAEV    AAS +KKPF  R KM                                    
Sbjct: 1   MVAEVSPKLAASPMKKPFGFRGKM------------------------------------ 24

Query: 61  MGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDL 120
            GKWCC CFPCCRGSGK+N+G W D+DDSAF EPRYHVRREDL KLHRAAWWG+VPR DL
Sbjct: 25  -GKWCCCCFPCCRGSGKNNMGAWRDHDDSAFTEPRYHVRREDLGKLHRAAWWGEVPRADL 83

Query: 121 IVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQ 180
           IVMLR   +NKRDK+KRTALHLA ANGNSEVV LLLDR+CQL+V D+KKRTALIKAVQCQ
Sbjct: 84  IVMLRGPGINKRDKKKRTALHLACANGNSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQ 143

Query: 181 EDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLL 240
           EDEC LMLL+HG D N+ D YGNTALHYA+YNEDKLMAK LLLYGADIESKNK GLTPLL
Sbjct: 144 EDECALMLLQHGTDPNLPDMYGNTALHYAVYNEDKLMAKTLLLYGADIESKNKGGLTPLL 203

Query: 241 LGVHEQKQEVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLS 300
           L VH QKQ +VKFLIKKKANLNALDR+GRTALILAV CGSASIV+LLL+QN+DV SQD+ 
Sbjct: 204 LAVHGQKQRMVKFLIKKKANLNALDRFGRTALILAVRCGSASIVSLLLQQNIDVFSQDVF 263

Query: 301 GQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQ 360
           GQTA +YAVSSHH +IC+LLSDYKE QM   SS NSNPEQDLKLTSEEE QRLK SENSQ
Sbjct: 264 GQTAEDYAVSSHHSIICQLLSDYKENQMPNNSSGNSNPEQDLKLTSEEEPQRLKGSENSQ 323

Query: 361 PEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPEN 420
            EK++QEP+INKDCDREVEEE++KHGSN VGL ENLT+GA+AGNGD GL+PQRKSRK EN
Sbjct: 324 HEKVTQEPDINKDCDREVEEEMQKHGSNNVGLSENLTDGAAAGNGDGGLVPQRKSRKHEN 383

Query: 421 QQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSELSLSHK 480
           QQFP+TE EEYH  E+   +K   + Q   +   + +T      E+A ++   +L  S+ 
Sbjct: 384 QQFPNTEIEEYHRPEKKSNEKNKVKSQIHSVDNLDDITWPS---EIASEDY--DLLFSNY 438

Query: 481 KEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILEE 520
           +   LL         I +L+++ +++   +++++  I EE
Sbjct: 439 ETFTLL---------IEQLKMDFNDSASLSKIQDAVISEE 469


>gi|50897294 POTE ankyrin domain family, member A isoform 1 [Homo
           sapiens]
          Length = 452

 Score =  540 bits (1391), Expect = e-153
 Identities = 296/520 (56%), Positives = 345/520 (66%), Gaps = 97/520 (18%)

Query: 1   MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGTSNVGTSGDHDDSFMKTLRSK 60
           MVAEV    AAS +KKPF  R KM                                    
Sbjct: 1   MVAEVSPKLAASPMKKPFGFRGKM------------------------------------ 24

Query: 61  MGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDL 120
            GKWCC CFPCCRGSGK+N+G W D+DDSAF EPRYHVRREDL KLHRAAWWG+VPR DL
Sbjct: 25  -GKWCCCCFPCCRGSGKNNMGAWRDHDDSAFTEPRYHVRREDLGKLHRAAWWGEVPRADL 83

Query: 121 IVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQ 180
           IVMLR   +NKRDK+KRTALHLA ANGNSEVV LLLDR+CQL+V D+KKRTALIKAVQCQ
Sbjct: 84  IVMLRGPGINKRDKKKRTALHLACANGNSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQ 143

Query: 181 EDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLL 240
           EDEC LMLL+HG D N+ D YGNTALHYA+YNEDKLMAK LLLYGADIESKNK GLTPLL
Sbjct: 144 EDECALMLLQHGTDPNLPDMYGNTALHYAVYNEDKLMAKTLLLYGADIESKNKGGLTPLL 203

Query: 241 LGVHEQKQEVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLS 300
           L VH QKQ +VKFLIKKKANLNALDR+GR                               
Sbjct: 204 LAVHGQKQRMVKFLIKKKANLNALDRFGR------------------------------- 232

Query: 301 GQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQ 360
                          IC+LLSDYKE QM   SS NSNPEQDLKLTSEEE QRLK SENSQ
Sbjct: 233 ---------------ICQLLSDYKENQMPNNSSGNSNPEQDLKLTSEEEPQRLKGSENSQ 277

Query: 361 PEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPEN 420
            EK++QEP+INKDCDREVEEE++KHGSN VGL ENLT+GA+AGNGD GL+PQRKSRK EN
Sbjct: 278 HEKVTQEPDINKDCDREVEEEMQKHGSNNVGLSENLTDGAAAGNGDGGLVPQRKSRKHEN 337

Query: 421 QQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSELSLSHK 480
           QQFP+TE EEYH  E+   +K   + Q   +   + +T      E+A ++   +L  S+ 
Sbjct: 338 QQFPNTEIEEYHRPEKKSNEKNKVKSQIHSVDNLDDITWPS---EIASEDY--DLLFSNY 392

Query: 481 KEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILEE 520
           +   LL         I +L+++ +++   +++++  I EE
Sbjct: 393 ETFTLL---------IEQLKMDFNDSASLSKIQDAVISEE 423


>gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo
           sapiens]
          Length = 917

 Score =  303 bits (776), Expect = 3e-82
 Identities = 195/477 (40%), Positives = 277/477 (58%), Gaps = 45/477 (9%)

Query: 77  KSNVGTWG-DYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQ 135
           +  + TW  + D   F  P Y VR++DL  +H+AA  G V +    ++LR  D+N RDK+
Sbjct: 12  RRRMATWRKNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKK 71

Query: 136 KRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADG 195
            RTAL LA A+G   VV  L+ R+CQLN+ D++ RTALIKAVQCQE+ C  +LLEHGA+ 
Sbjct: 72  NRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANP 131

Query: 196 NIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLI 255
           N++D YGNTALHYAI NE+  MA+ LL YGADIE++++ G T LLL V+ +K+++V FL+
Sbjct: 132 NVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVAFLL 191

Query: 256 KKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHV 315
           KKK +L A+D +GRTALILA   GS S+V  LL+ N+DV  QD+SG TA +YAV+S    
Sbjct: 192 KKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQA 251

Query: 316 ICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCD 375
           I  ++S+YK  +  K S +NSN EQDL++TSE E +RL+  E+SQP              
Sbjct: 252 IRGMISEYKANKRCK-SLQNSNSEQDLEMTSEGEQERLEGCESSQP-------------- 296

Query: 376 REVEEEIKKHGSNPVGLPENLTNGASAGNGD--DGLIPQRKSRKPENQQFPDTENEE--- 430
            +VEE++KK  +  + +  N+    S    D  D LI + K+RKP+N Q P  EN E   
Sbjct: 297 -QVEEKMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDR 355

Query: 431 ----------------YHSDEQND---TQKQLSEEQNTGISQDEILTNKQKQIEVAEKEM 471
                           Y +D+ ND   + ++ SE+     S DE   N    IE +  E 
Sbjct: 356 LARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDE---NFMLLIEQSGMEC 412

Query: 472 NSELSLSHKKEEDLLRENSMLREEIAKLRLELDETKHQNQLRE-NKILEEIESVKEK 527
              +SLS  K        S+  ++    RL++   K +N +    K+L E +  K +
Sbjct: 413 KDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQ 469



 Score =  104 bits (259), Expect = 2e-22
 Identities = 120/464 (25%), Positives = 203/464 (43%), Gaps = 58/464 (12%)

Query: 128 DMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLM 187
           D+  R +   T+L LA      ++V  LL ++  L  +DN  RTALI A +      V  
Sbjct: 163 DIEARSQDGHTSLLLAVNRKKEQMVAFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQ 222

Query: 188 LLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGA--------------DIESKNK 233
           LL+H  D   QD  G TA  YA+ ++ + +   +  Y A              D+E  ++
Sbjct: 223 LLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRCKSLQNSNSEQDLEMTSE 282

Query: 234 CGLTPLLLGVHEQKQEVV---------KFLIKKKANLNALDRYGRTALILAVCCGSASIV 284
            G    L G    + +V          K  + +  + +  D Y      L     +    
Sbjct: 283 -GEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPD 341

Query: 285 NLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKL 344
           N       +     L+ +T+ E +         + L+D      +  SSE ++ + +L  
Sbjct: 342 NHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLND------ISGSSEKTSEDDELPY 395

Query: 345 TSEEESQRLKVSENSQPEK----MSQEPEINKDCDREVEEE----------IKKHGSNPV 390
            S++E+  L + ++    K    +S+       C R +E++           +K  +N  
Sbjct: 396 -SDDENFMLLIEQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNIS 454

Query: 391 GLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSD-----EQNDTQKQLSE 445
            L + L+      +  +    Q K +K  N +F   + EE         E++  + ++ E
Sbjct: 455 VLQKVLSETDKTKSQSEHQNLQGK-KKLCNLRFILQQQEEERIKAEELYEKDIEELKIME 513

Query: 446 EQ---NTGISQDEILTNKQKQIEVAEKEMNSELSL-SHKKEEDLLRENSMLREEIAKLRL 501
           EQ    T + +   LT K  ++E+     NS  +  +H++E DL +EN ++R+EIA+LRL
Sbjct: 514 EQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRL 573

Query: 502 ELDETKHQNQLRENKILEEIESVKEK---LLKTIQLNEEALTKT 542
           E+D  KHQNQ  ENK  ++IE +KE    L KT++ NEEALTKT
Sbjct: 574 EIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEEALTKT 617


>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
          Length = 917

 Score =  301 bits (772), Expect = 8e-82
 Identities = 194/477 (40%), Positives = 277/477 (58%), Gaps = 45/477 (9%)

Query: 77  KSNVGTWG-DYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQ 135
           +  + TW  + D   F  P Y VR++DL  +H+AA  G V +    ++LR  D+N RDK+
Sbjct: 12  RRRMATWRKNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKK 71

Query: 136 KRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADG 195
            RTAL LA A+G   VV  L+ R+CQLN+ D++ RTALIKAVQCQE+ C  +LLEHGA+ 
Sbjct: 72  NRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANP 131

Query: 196 NIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLI 255
           N++D YGNTALHYAI NE+  MA+ LL YGADIE++++ G T LLL V+ +K+++V FL+
Sbjct: 132 NVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLL 191

Query: 256 KKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHV 315
           KKK +L A+D +GRTALILA   GS S+V  LL+ N+DV  QD+SG TA +YAV+S    
Sbjct: 192 KKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQA 251

Query: 316 ICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCD 375
           I  ++S+YK  +  K S +NSN EQDL++TSE E +RL+  E+SQP              
Sbjct: 252 IRGMISEYKANKRRK-SLQNSNSEQDLEMTSEGEQERLEGCESSQP-------------- 296

Query: 376 REVEEEIKKHGSNPVGLPENLTNGASAGNGD--DGLIPQRKSRKPENQQFPDTENEE--- 430
            +VEE++KK  +  + +  N+    S    D  D LI + K+RKP+N Q P  EN E   
Sbjct: 297 -QVEEKMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDR 355

Query: 431 ----------------YHSDEQND---TQKQLSEEQNTGISQDEILTNKQKQIEVAEKEM 471
                           Y +D+ ND   + ++ SE+     S DE   N    I+ +  E 
Sbjct: 356 LARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDE---NFMLLIKQSGMEC 412

Query: 472 NSELSLSHKKEEDLLRENSMLREEIAKLRLELDETKHQNQLRE-NKILEEIESVKEK 527
              +SLS  K        S+  ++    RL++   K +N +    K+L E +  K +
Sbjct: 413 KDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQ 469



 Score =  103 bits (256), Expect = 5e-22
 Identities = 119/464 (25%), Positives = 202/464 (43%), Gaps = 58/464 (12%)

Query: 128 DMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLM 187
           D+  R +   T+L LA      ++V  LL ++  L  +DN  RTALI A +      V  
Sbjct: 163 DIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQ 222

Query: 188 LLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGA--------------DIESKNK 233
           LL+H  D   QD  G TA  YA+ ++ + +   +  Y A              D+E  ++
Sbjct: 223 LLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSE 282

Query: 234 CGLTPLLLGVHEQKQEVV---------KFLIKKKANLNALDRYGRTALILAVCCGSASIV 284
            G    L G    + +V          K  + +  + +  D Y      L     +    
Sbjct: 283 -GEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPD 341

Query: 285 NLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKL 344
           N       +     L+ +T+ E +         + L+D      +  SSE ++ + +L  
Sbjct: 342 NHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLND------ISGSSEKTSEDDELPY 395

Query: 345 TSEEESQRLKVSENSQPEK----MSQEPEINKDCDREVEEE----------IKKHGSNPV 390
            S++E+  L + ++    K    +S+       C R +E++           +K  +N  
Sbjct: 396 -SDDENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNIS 454

Query: 391 GLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSD-----EQNDTQKQLSE 445
            L + L+      +  +    Q K +K  N +F   + EE         E++  + ++ E
Sbjct: 455 VLQKVLSETDKTKSQSEHQNLQGK-KKLCNLRFILQQQEEERIKAEELYEKDIEELKIME 513

Query: 446 EQ---NTGISQDEILTNKQKQIEVAEKEMNSELSL-SHKKEEDLLRENSMLREEIAKLRL 501
           EQ    T + +   LT K  ++E+     NS  +  +H++E DL +EN ++R+EIA+LRL
Sbjct: 514 EQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRL 573

Query: 502 ELDETKHQNQLRENKILEEIESVKEK---LLKTIQLNEEALTKT 542
           E+D  KHQNQ  ENK  ++IE +KE    L KT++ NEE LTKT
Sbjct: 574 EIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKT 617


>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
           sapiens]
          Length = 917

 Score =  301 bits (772), Expect = 8e-82
 Identities = 194/477 (40%), Positives = 277/477 (58%), Gaps = 45/477 (9%)

Query: 77  KSNVGTWG-DYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQ 135
           +  + TW  + D   F  P Y VR++DL  +H+AA  G V +    ++LR  D+N RDK+
Sbjct: 12  RRRMATWRKNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKK 71

Query: 136 KRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADG 195
            RTAL LA A+G   VV  L+ R+CQLN+ D++ RTALIKAVQCQE+ C  +LLEHGA+ 
Sbjct: 72  NRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANP 131

Query: 196 NIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLI 255
           N++D YGNTALHYAI NE+  MA+ LL YGADIE++++ G T LLL V+ +K+++V FL+
Sbjct: 132 NVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLL 191

Query: 256 KKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHV 315
           KKK +L A+D +GRTALILA   GS S+V  LL+ N+DV  QD+SG TA +YAV+S    
Sbjct: 192 KKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQA 251

Query: 316 ICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCD 375
           I  ++S+YK  +  K S +NSN EQDL++TSE E +RL+  E+SQP              
Sbjct: 252 IRGMISEYKANKRRK-SLQNSNSEQDLEMTSEGEQERLEGCESSQP-------------- 296

Query: 376 REVEEEIKKHGSNPVGLPENLTNGASAGNGD--DGLIPQRKSRKPENQQFPDTENEE--- 430
            +VEE++KK  +  + +  N+    S    D  D LI + K+RKP+N Q P  EN E   
Sbjct: 297 -QVEEKMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDR 355

Query: 431 ----------------YHSDEQND---TQKQLSEEQNTGISQDEILTNKQKQIEVAEKEM 471
                           Y +D+ ND   + ++ SE+     S DE   N    I+ +  E 
Sbjct: 356 LARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDE---NFMLLIKQSGMEC 412

Query: 472 NSELSLSHKKEEDLLRENSMLREEIAKLRLELDETKHQNQLRE-NKILEEIESVKEK 527
              +SLS  K        S+  ++    RL++   K +N +    K+L E +  K +
Sbjct: 413 KDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQ 469



 Score =  103 bits (256), Expect = 5e-22
 Identities = 119/464 (25%), Positives = 202/464 (43%), Gaps = 58/464 (12%)

Query: 128 DMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLM 187
           D+  R +   T+L LA      ++V  LL ++  L  +DN  RTALI A +      V  
Sbjct: 163 DIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQ 222

Query: 188 LLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGA--------------DIESKNK 233
           LL+H  D   QD  G TA  YA+ ++ + +   +  Y A              D+E  ++
Sbjct: 223 LLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSE 282

Query: 234 CGLTPLLLGVHEQKQEVV---------KFLIKKKANLNALDRYGRTALILAVCCGSASIV 284
            G    L G    + +V          K  + +  + +  D Y      L     +    
Sbjct: 283 -GEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPD 341

Query: 285 NLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKL 344
           N       +     L+ +T+ E +         + L+D      +  SSE ++ + +L  
Sbjct: 342 NHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLND------ISGSSEKTSEDDELPY 395

Query: 345 TSEEESQRLKVSENSQPEK----MSQEPEINKDCDREVEEE----------IKKHGSNPV 390
            S++E+  L + ++    K    +S+       C R +E++           +K  +N  
Sbjct: 396 -SDDENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNIS 454

Query: 391 GLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSD-----EQNDTQKQLSE 445
            L + L+      +  +    Q K +K  N +F   + EE         E++  + ++ E
Sbjct: 455 VLQKVLSETDKTKSQSEHQNLQGK-KKLCNLRFILQQQEEERIKAEELYEKDIEELKIME 513

Query: 446 EQ---NTGISQDEILTNKQKQIEVAEKEMNSELSL-SHKKEEDLLRENSMLREEIAKLRL 501
           EQ    T + +   LT K  ++E+     NS  +  +H++E DL +EN ++R+EIA+LRL
Sbjct: 514 EQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRL 573

Query: 502 ELDETKHQNQLRENKILEEIESVKEK---LLKTIQLNEEALTKT 542
           E+D  KHQNQ  ENK  ++IE +KE    L KT++ NEE LTKT
Sbjct: 574 EIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKT 617


>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo
           sapiens]
          Length = 823

 Score =  253 bits (646), Expect = 3e-67
 Identities = 184/553 (33%), Positives = 289/553 (52%), Gaps = 97/553 (17%)

Query: 88  DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANG 147
           D  +    Y +R  +L K+HRAA  G     +  +  R  D++  DKQ RTALHLA A+G
Sbjct: 19  DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASG 78

Query: 148 NSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALH 207
           + +VV LL++R+CQ++V D + RT LI+AV CQE+ C ++LLEHGA+ N++D YGNTALH
Sbjct: 79  HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138

Query: 208 YAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNALDRY 267
           YA+Y+E   +A+ LL +GA IE+ +K   TPLL  +  +K+++V+FL+K+KA+ +A+DR 
Sbjct: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHAVDRL 198

Query: 268 GRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQ 327
            R+AL+LAV   S  IVN+LL+QN+DV +QD+ G+ A +YA+S H   I + + ++K+K 
Sbjct: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258

Query: 328 MLKISSE-NSNPEQDLKLTSEEESQRLKVSENSQ---------PEKMS------------ 365
           + K  S+  S+ E  + +  E     L  S++           PEK+S            
Sbjct: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGN 318

Query: 366 -----------------------QEPEINKDCDRE--------------VEEEIKKHGSN 388
                                  ++P +     R+               EEE ++H  +
Sbjct: 319 RIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQERHERS 378

Query: 389 PVGLPE----NLTNGA-----------SAGNGDDGLIPQ-RKSRKPENQQFPDTENEEY- 431
               P+    N TN +           S  +   G + Q RK  K   QQFP    EE+ 
Sbjct: 379 EKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHD 438

Query: 432 -----HSDEQNDTQKQLSEEQNTGISQDEILTNKQ---KQIE--VAEKEMNSELSL---- 477
                  +E+      L ++    + + E    K+   KQ+E  V   EM S+ +     
Sbjct: 439 RCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498

Query: 478 ----SHKKEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILEEIESVKE---KLLK 530
               +H++ + L+ EN +L+ +IA LR E+   K+ N  +ENK L++I+ VKE    L K
Sbjct: 499 RDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558

Query: 531 TIQLNEEALTKTS 543
            I+LNEE +T+T+
Sbjct: 559 YIKLNEEMITETA 571


>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo
           sapiens]
          Length = 823

 Score =  253 bits (646), Expect = 3e-67
 Identities = 184/553 (33%), Positives = 289/553 (52%), Gaps = 97/553 (17%)

Query: 88  DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANG 147
           D  +    Y +R  +L K+HRAA  G     +  +  R  D++  DKQ RTALHLA A+G
Sbjct: 19  DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASG 78

Query: 148 NSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALH 207
           + +VV LL++R+CQ++V D + RT LI+AV CQE+ C ++LLEHGA+ N++D YGNTALH
Sbjct: 79  HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138

Query: 208 YAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNALDRY 267
           YA+Y+E   +A+ LL +GA IE+ +K   TPLL  +  +K+++V+FL+K+KA+ +A+DR 
Sbjct: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHAVDRL 198

Query: 268 GRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQ 327
            R+AL+LAV   S  IVN+LL+QN+DV +QD+ G+ A +YA+S H   I + + ++K+K 
Sbjct: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258

Query: 328 MLKISSE-NSNPEQDLKLTSEEESQRLKVSENSQ---------PEKMS------------ 365
           + K  S+  S+ E  + +  E     L  S++           PEK+S            
Sbjct: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGN 318

Query: 366 -----------------------QEPEINKDCDRE--------------VEEEIKKHGSN 388
                                  ++P +     R+               EEE ++H  +
Sbjct: 319 RIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQERHERS 378

Query: 389 PVGLPE----NLTNGA-----------SAGNGDDGLIPQ-RKSRKPENQQFPDTENEEY- 431
               P+    N TN +           S  +   G + Q RK  K   QQFP    EE+ 
Sbjct: 379 EKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHD 438

Query: 432 -----HSDEQNDTQKQLSEEQNTGISQDEILTNKQ---KQIE--VAEKEMNSELSL---- 477
                  +E+      L ++    + + E    K+   KQ+E  V   EM S+ +     
Sbjct: 439 RCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498

Query: 478 ----SHKKEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILEEIESVKE---KLLK 530
               +H++ + L+ EN +L+ +IA LR E+   K+ N  +ENK L++I+ VKE    L K
Sbjct: 499 RDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558

Query: 531 TIQLNEEALTKTS 543
            I+LNEE +T+T+
Sbjct: 559 YIKLNEEMITETA 571


>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
           sapiens]
          Length = 823

 Score =  253 bits (645), Expect = 4e-67
 Identities = 184/553 (33%), Positives = 288/553 (52%), Gaps = 97/553 (17%)

Query: 88  DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANG 147
           D  +    Y +R  +L K+HRAA  G     +  +  R  D++  DKQ RTALHLA  +G
Sbjct: 19  DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACTSG 78

Query: 148 NSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALH 207
           + +VV LL++R+CQ++V D + RT LI+AV CQE+ C ++LLEHGA+ N++D YGNTALH
Sbjct: 79  HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138

Query: 208 YAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNALDRY 267
           YA+Y+E   +A+ LL +GA IE+ +K   TPLL  +  +K+++V+FL+KKKA+ +A+DR 
Sbjct: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRL 198

Query: 268 GRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQ 327
            R+AL+LAV   S  IVN+LL+QN+DV +QD+ G+ A +YA+S H   I + + ++K+K 
Sbjct: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258

Query: 328 MLKISSE-NSNPEQDLKLTSEEESQRLKVSENSQ---------PEKMS------------ 365
           + K  S+  S+ E  + +  E     L  S++           PEK+S            
Sbjct: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGN 318

Query: 366 -----------------------QEPEINKDCDRE--------------VEEEIKKHGSN 388
                                  ++P +     R+               EEE ++H  +
Sbjct: 319 RIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQERHERS 378

Query: 389 PVGLPE----NLTNGA-----------SAGNGDDGLIPQ-RKSRKPENQQFPDTENEEY- 431
               P+    N TN +           S  +   G + Q RK  K   QQFP    EE+ 
Sbjct: 379 EKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHD 438

Query: 432 -----HSDEQNDTQKQLSEEQNTGISQDEILTNKQ---KQIE--VAEKEMNSELSL---- 477
                  +E+      L ++    + + E    K+   KQ+E  V   EM S+ +     
Sbjct: 439 RCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498

Query: 478 ----SHKKEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILEEIESVKE---KLLK 530
               +H++ + L+ EN +L+ +IA LR E+   K+ N  +ENK L++I+ VKE    L K
Sbjct: 499 WDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558

Query: 531 TIQLNEEALTKTS 543
            I+LNEE +T+T+
Sbjct: 559 YIKLNEEMITETA 571


>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
           sapiens]
          Length = 823

 Score =  253 bits (645), Expect = 4e-67
 Identities = 184/553 (33%), Positives = 289/553 (52%), Gaps = 97/553 (17%)

Query: 88  DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANG 147
           D  +    Y +R  +L K+HRAA  G     +  +  R  +++  DKQ RTALHLA A+G
Sbjct: 19  DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELDALDKQHRTALHLACASG 78

Query: 148 NSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALH 207
           + +VV LL++R+CQ++V D + RT LI+AV CQE+ C ++LLEHGA+ N++D YGNTALH
Sbjct: 79  HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138

Query: 208 YAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNALDRY 267
           YA+Y+E   +A+ LL +GA IE+ +K   TPLL  +  +K+++V+FL+KKKA+ +A+DR 
Sbjct: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRL 198

Query: 268 GRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQ 327
            R+AL+LAV   S  IVN+LL+QN+DV +QD+ G+ A +YA+S H   I + + ++K+K 
Sbjct: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258

Query: 328 MLKISSE-NSNPEQDLKLTSEEESQRLKVSENSQ---------PEKMS------------ 365
           + K  S+  S+ E  + +  E     L  S++           PEK+S            
Sbjct: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGN 318

Query: 366 -----------------------QEPEINKDCDRE--------------VEEEIKKHGSN 388
                                  ++P +     R+               EEE ++H  +
Sbjct: 319 RIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQQRHERS 378

Query: 389 PVGLPE----NLTNGA-----------SAGNGDDGLIPQ-RKSRKPENQQFPDTENEEY- 431
               P+    N TN +           S  +   G + Q RK  K   QQFP    EE+ 
Sbjct: 379 EKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHD 438

Query: 432 -----HSDEQNDTQKQLSEEQNTGISQDEILTNKQ---KQIE--VAEKEMNSELSL---- 477
                  +E+      L ++    + + E    K+   KQ+E  V   EM S+ +     
Sbjct: 439 RCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498

Query: 478 ----SHKKEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILEEIESVKE---KLLK 530
               +H++ + L+ EN +L+ +IA LR E+   K+ N  +ENK L++I+ VKE    L K
Sbjct: 499 WDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558

Query: 531 TIQLNEEALTKTS 543
            I+LNEE +T+T+
Sbjct: 559 YIKLNEEMITETA 571


>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1363

 Score =  249 bits (635), Expect = 6e-66
 Identities = 170/507 (33%), Positives = 271/507 (53%), Gaps = 66/507 (13%)

Query: 88  DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANG 147
           D  +    YH+R  +L K+HRAA  G     +  +  R  D++ RDK+ RT LHLA A+G
Sbjct: 119 DQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHG 178

Query: 148 NSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALH 207
             +VV LLLDR+CQ+N+ D   RT L+KAV CQE+ C ++LL+ GA+ NI+D YGNTALH
Sbjct: 179 RVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALH 238

Query: 208 YAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNALDRY 267
           YA+YNE   +A+ LL + A+IE+ NK G TPLL  ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 239 YAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 298

Query: 268 GRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQ 327
            RTALILAV    +SIV LLL+QN+ +SSQD+ GQTA +YA       I + + ++K K 
Sbjct: 299 KRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKM 358

Query: 328 M---------------------------LKISSENSNPEQDLKLTSEEESQRLKVSENSQ 360
           +                           LK   E +  E +LK+ SEE+ +RL+ SEN Q
Sbjct: 359 LKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQ 418

Query: 361 PE------KMSQEPEINKDCDREV---EEEI-----------KKHGSNPVGLPENLTNGA 400
           P+      K   E   N    R++   +EE+           KK+      + E   N  
Sbjct: 419 PQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFE 478

Query: 401 SAGNGDDGLIPQRKSR--------KPENQQFPDTENEEYHSDEQNDTQ-KQLSEEQNTGI 451
            +   ++ +I ++ ++        K EN +      +E H+ E+ + + + L     T I
Sbjct: 479 KSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAI 538

Query: 452 SQ-DEILTNKQKQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAKLRLELDETKHQN 510
           ++ +EIL  K  ++ +   +  S           L  +N +L E++ K R++ +  K   
Sbjct: 539 NEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLK--- 595

Query: 511 QLRENKILEEIESVKEK--LLKTIQLN 535
                K+ E  ++++EK   L+++QL+
Sbjct: 596 ----GKLRETRDALREKTLALESVQLD 618



 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 106/423 (25%), Positives = 194/423 (45%), Gaps = 66/423 (15%)

Query: 124 LRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQ-LNVLDNKKRTALIKAVQCQED 182
           +RD ++ K        +H A+  G++  V+  L RR + L+V D K RT L  A      
Sbjct: 129 IRDWELRK--------IHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHGRV 180

Query: 183 ECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLG 242
           + V +LL+     NI D    T L  A++ +++  A  LL  GA+   K+  G T L   
Sbjct: 181 QVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYA 240

Query: 243 VHEQKQEVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQ 302
           V+ +   + + L+   AN+ AL++ G T L+ A+      +V  LL+   ++ + D   +
Sbjct: 241 VYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKR 300

Query: 303 TAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPE 362
           TA   AV  +   I  LL     +Q + ISS++   +     T+E+ +            
Sbjct: 301 TALILAVQHNLSSIVTLLL----QQNIHISSQDMFGQ-----TAEDYAFC---------- 341

Query: 363 KMSQEPEINKDCD-REVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQ 421
                      CD R ++++I +H +  +       N  +A    + L  ++K +K + +
Sbjct: 342 -----------CDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKR 390

Query: 422 QFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSELSLSHKK 481
           +                  +    E N  ++ +E    KQ+++E +E +   + S S+ K
Sbjct: 391 K------------------EGAKAEHNLKVASEE----KQERLERSENKQPQD-SQSYGK 427

Query: 482 EEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILEEIESVKE---KLLKTIQLNEEA 538
           ++D +  N ML+ +IA L+ EL   K+ +  +E K ++EI+S+ E      K+++LNEE 
Sbjct: 428 KKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEM 487

Query: 539 LTK 541
           +TK
Sbjct: 488 ITK 490



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 34/153 (22%), Positives = 69/153 (45%), Gaps = 16/153 (10%)

Query: 408  GLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQLSE--EQNTGISQDEILTNKQ---- 461
            G + + KS   E       + EE H  +Q + +KQL +  + NT   + + LT K     
Sbjct: 925  GKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECK 984

Query: 462  -KQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAK---------LRLELDETKHQNQ 511
              +++ A +++ +EL    +     L+ NS + E+I K          +L +++ + +  
Sbjct: 985  FSKMKTAYEDVTTELEEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEYF 1044

Query: 512  LRENKILEEIESVKEKLLKTIQLNEEALTKTSI 544
            L    +  + E    + L +I+LN + + K +I
Sbjct: 1045 LSTLPMRPDPELPCVENLNSIELNRKYIPKMAI 1077


>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1366

 Score =  249 bits (635), Expect = 6e-66
 Identities = 170/507 (33%), Positives = 271/507 (53%), Gaps = 66/507 (13%)

Query: 88  DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANG 147
           D  +    YH+R  +L K+HRAA  G     +  +  R  D++ RDK+ RT LHLA A+G
Sbjct: 148 DQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHG 207

Query: 148 NSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALH 207
             +VV LLLDR+CQ+N+ D   RT L+KAV CQE+ C ++LL+ GA+ NI+D YGNTALH
Sbjct: 208 RVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALH 267

Query: 208 YAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNALDRY 267
           YA+YNE   +A+ LL + A+IE+ NK G TPLL  ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 268 YAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 327

Query: 268 GRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQ 327
            RTALILAV    +SIV LLL+QN+ +SSQD+ GQTA +YA       I + + ++K K 
Sbjct: 328 KRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKM 387

Query: 328 M---------------------------LKISSENSNPEQDLKLTSEEESQRLKVSENSQ 360
           +                           LK   E +  E +LK+ SEE+ +RL+ SEN Q
Sbjct: 388 LKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQ 447

Query: 361 PE------KMSQEPEINKDCDREV---EEEI-----------KKHGSNPVGLPENLTNGA 400
           P+      K   E   N    R++   +EE+           KK+      + E   N  
Sbjct: 448 PQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFE 507

Query: 401 SAGNGDDGLIPQRKSR--------KPENQQFPDTENEEYHSDEQNDTQ-KQLSEEQNTGI 451
            +   ++ +I ++ ++        K EN +      +E H+ E+ + + + L     T I
Sbjct: 508 KSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAI 567

Query: 452 SQ-DEILTNKQKQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAKLRLELDETKHQN 510
           ++ +EIL  K  ++ +   +  S           L  +N +L E++ K R++ +  K   
Sbjct: 568 NEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLK--- 624

Query: 511 QLRENKILEEIESVKEK--LLKTIQLN 535
                K+ E  ++++EK   L+++QL+
Sbjct: 625 ----GKLRETRDALREKTLALESVQLD 647



 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 106/423 (25%), Positives = 194/423 (45%), Gaps = 66/423 (15%)

Query: 124 LRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQ-LNVLDNKKRTALIKAVQCQED 182
           +RD ++ K        +H A+  G++  V+  L RR + L+V D K RT L  A      
Sbjct: 158 IRDWELRK--------IHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHGRV 209

Query: 183 ECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLG 242
           + V +LL+     NI D    T L  A++ +++  A  LL  GA+   K+  G T L   
Sbjct: 210 QVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYA 269

Query: 243 VHEQKQEVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQ 302
           V+ +   + + L+   AN+ AL++ G T L+ A+      +V  LL+   ++ + D   +
Sbjct: 270 VYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKR 329

Query: 303 TAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPE 362
           TA   AV  +   I  LL     +Q + ISS++   +     T+E+ +            
Sbjct: 330 TALILAVQHNLSSIVTLLL----QQNIHISSQDMFGQ-----TAEDYAFC---------- 370

Query: 363 KMSQEPEINKDCD-REVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQ 421
                      CD R ++++I +H +  +       N  +A    + L  ++K +K + +
Sbjct: 371 -----------CDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKR 419

Query: 422 QFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSELSLSHKK 481
           +                  +    E N  ++ +E    KQ+++E +E +   + S S+ K
Sbjct: 420 K------------------EGAKAEHNLKVASEE----KQERLERSENKQPQD-SQSYGK 456

Query: 482 EEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILEEIESVKE---KLLKTIQLNEEA 538
           ++D +  N ML+ +IA L+ EL   K+ +  +E K ++EI+S+ E      K+++LNEE 
Sbjct: 457 KKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEM 516

Query: 539 LTK 541
           +TK
Sbjct: 517 ITK 519



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 34/153 (22%), Positives = 69/153 (45%), Gaps = 16/153 (10%)

Query: 408  GLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQLSE--EQNTGISQDEILTNKQ---- 461
            G + + KS   E       + EE H  +Q + +KQL +  + NT   + + LT K     
Sbjct: 954  GKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECK 1013

Query: 462  -KQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAK---------LRLELDETKHQNQ 511
              +++ A +++ +EL    +     L+ NS + E+I K          +L +++ + +  
Sbjct: 1014 FSKMKTAYEDVTTELEEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEYF 1073

Query: 512  LRENKILEEIESVKEKLLKTIQLNEEALTKTSI 544
            L    +  + E    + L +I+LN + + K +I
Sbjct: 1074 LSTLPMRPDPELPCVENLNSIELNRKYIPKMAI 1106


>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1139

 Score =  248 bits (632), Expect = 1e-65
 Identities = 169/507 (33%), Positives = 271/507 (53%), Gaps = 66/507 (13%)

Query: 88  DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANG 147
           D  +    YH+R  +L K+HRAA  G     +  +  R  D++ RD++ RT LHLA A+G
Sbjct: 148 DQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDRKDRTVLHLACAHG 207

Query: 148 NSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALH 207
             +VV LLLDR+CQ+N+ D   RT L+KAV CQE+ C ++LL+ GA+ NI+D YGNTALH
Sbjct: 208 RVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALH 267

Query: 208 YAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNALDRY 267
           YA+YNE   +A+ LL + A+IE+ NK G TPLL  ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 268 YAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 327

Query: 268 GRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQ 327
            RTALILAV    +SIV LLL+QN+ +SSQD+ GQTA +YA       I + + ++K K 
Sbjct: 328 KRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKM 387

Query: 328 M---------------------------LKISSENSNPEQDLKLTSEEESQRLKVSENSQ 360
           +                           LK   E +  E +LK+ SEE+ +RL+ SEN Q
Sbjct: 388 LKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQ 447

Query: 361 PE------KMSQEPEINKDCDREV---EEEI-----------KKHGSNPVGLPENLTNGA 400
           P+      K   E   N    R++   +EE+           KK+      + E   N  
Sbjct: 448 PQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFE 507

Query: 401 SAGNGDDGLIPQRKSR--------KPENQQFPDTENEEYHSDEQNDTQ-KQLSEEQNTGI 451
            +   ++ +I ++ ++        K EN +      +E H+ E+ + + + L     T I
Sbjct: 508 KSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAI 567

Query: 452 SQ-DEILTNKQKQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAKLRLELDETKHQN 510
           ++ +EIL  K  ++ +   +  S           L  +N +L E++ K R++ +  K   
Sbjct: 568 NEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLK--- 624

Query: 511 QLRENKILEEIESVKEK--LLKTIQLN 535
                K+ E  ++++EK   L+++QL+
Sbjct: 625 ----GKLRETRDALREKTLALESVQLD 647



 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 106/423 (25%), Positives = 194/423 (45%), Gaps = 66/423 (15%)

Query: 124 LRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQ-LNVLDNKKRTALIKAVQCQED 182
           +RD ++ K        +H A+  G++  V+  L RR + L+V D K RT L  A      
Sbjct: 158 IRDWELRK--------IHRAAIKGDAAEVEHCLTRRFRDLDVRDRKDRTVLHLACAHGRV 209

Query: 183 ECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLG 242
           + V +LL+     NI D    T L  A++ +++  A  LL  GA+   K+  G T L   
Sbjct: 210 QVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYA 269

Query: 243 VHEQKQEVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQ 302
           V+ +   + + L+   AN+ AL++ G T L+ A+      +V  LL+   ++ + D   +
Sbjct: 270 VYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKR 329

Query: 303 TAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPE 362
           TA   AV  +   I  LL     +Q + ISS++   +     T+E+ +            
Sbjct: 330 TALILAVQHNLSSIVTLLL----QQNIHISSQDMFGQ-----TAEDYAFC---------- 370

Query: 363 KMSQEPEINKDCD-REVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQ 421
                      CD R ++++I +H +  +       N  +A    + L  ++K +K + +
Sbjct: 371 -----------CDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKR 419

Query: 422 QFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSELSLSHKK 481
           +                  +    E N  ++ +E    KQ+++E +E +   + S S+ K
Sbjct: 420 K------------------EGAKAEHNLKVASEE----KQERLERSENKQPQD-SQSYGK 456

Query: 482 EEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILEEIESVKE---KLLKTIQLNEEA 538
           ++D +  N ML+ +IA L+ EL   K+ +  +E K ++EI+S+ E      K+++LNEE 
Sbjct: 457 KKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEM 516

Query: 539 LTK 541
           +TK
Sbjct: 517 ITK 519



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 34/153 (22%), Positives = 69/153 (45%), Gaps = 16/153 (10%)

Query: 408  GLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQLSE--EQNTGISQDEILTNKQ---- 461
            G + + KS   E       + EE H  +Q + +KQL +  + NT   + + LT K     
Sbjct: 954  GKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECK 1013

Query: 462  -KQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAK---------LRLELDETKHQNQ 511
              +++ A +++ +EL    +     L+ NS + E+I K          +L +++ + +  
Sbjct: 1014 FSKMKTAYEDVTTELEEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEYF 1073

Query: 512  LRENKILEEIESVKEKLLKTIQLNEEALTKTSI 544
            L    +  + E    + L +I+LN + + K +I
Sbjct: 1074 LSTLPMRPDPELPCVENLNSIELNRKYIPKMAI 1106


>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
           [Homo sapiens]
          Length = 823

 Score =  244 bits (622), Expect = 2e-64
 Identities = 174/554 (31%), Positives = 283/554 (51%), Gaps = 99/554 (17%)

Query: 88  DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANG 147
           D  +    Y +R  +L K+H+AA  G     +  +  R  D++  DKQ RTALHLA A+G
Sbjct: 19  DHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLDALDKQHRTALHLACASG 78

Query: 148 NSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALH 207
           + +VV LL++R+CQ+++ D + RT LI+AV CQE+ C ++LLEHGA+ N++D YGNTALH
Sbjct: 79  HVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138

Query: 208 YAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNALDRY 267
           YA+Y+E   +A+ LL +G +IE+ +K   TPLL  +  +K+++V+FL+K KA+ +A+DR 
Sbjct: 139 YAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHAVDRL 198

Query: 268 GRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVS----------------- 310
             TAL+LAV   S  IVN+LL+Q+++V +QD+ G+ A +YA+S                 
Sbjct: 199 RXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAISCRLTKIQQQILEHKKMI 258

Query: 311 ----------------SHHHVICELLSDYKEKQMLKISSENSNPEQ-------------- 340
                           S  H +C       + ++L ++++   PE+              
Sbjct: 259 LKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQCVPEKVSEPLRGPSHGKGN 318

Query: 341 ---------------DLKLTSEEESQRLKVS---ENSQPEKMSQEPEINKDCDREVEEEI 382
                           LK ++E E   +K +   +N Q  +  Q   +  + +++  E  
Sbjct: 319 RIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRAEQALPVASEEEQQRRERS 378

Query: 383 KK-----------HGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEY 431
           +K           + S  + L EN+ +   +    D L  QRK  K   QQFP    EE+
Sbjct: 379 EKKQPQVIEGNNTYKSEKIQLSENICHSTFSA-AADRLTQQRKIGKTYPQQFPKKLKEEH 437

Query: 432 ------HSDEQNDTQKQLSEEQNTGISQDEILTNKQ---KQIE--VAEKEMNSELSL--- 477
                   +E+      L ++    + + E    K+   KQ+E  V   EM  + +    
Sbjct: 438 DRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKPKTARNTP 497

Query: 478 -----SHKKEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILEEIESVKE---KLL 529
                +H++ +DL+ EN +L+ +IA LR E+   K+ N  +ENK L++I+  KE    L 
Sbjct: 498 NQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALE 557

Query: 530 KTIQLNEEALTKTS 543
           K I+LNEE +TKT+
Sbjct: 558 KCIKLNEEMITKTA 571


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,234,371
Number of Sequences: 37866
Number of extensions: 973726
Number of successful extensions: 12067
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 541
Number of HSP's successfully gapped in prelim test: 791
Number of HSP's that attempted gapping in prelim test: 5023
Number of HSP's gapped (non-prelim): 4701
length of query: 544
length of database: 18,247,518
effective HSP length: 107
effective length of query: 437
effective length of database: 14,195,856
effective search space: 6203589072
effective search space used: 6203589072
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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