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Search of human proteins with 239745044
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239745044 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
(368 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239745044 PREDICTED: similar to breast cancer anti-estrogen r... 774 0.0
gi|239745060 PREDICTED: similar to breast cancer anti-estrogen r... 591 e-169
gi|239756225 PREDICTED: similar to breast cancer anti-estrogen r... 452 e-127
gi|239750776 PREDICTED: similar to breast cancer anti-estrogen r... 452 e-127
gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens] 441 e-124
gi|5453680 neural precursor cell expressed, developmentally down... 134 1e-31
gi|215422375 neural precursor cell expressed, developmentally do... 132 4e-31
gi|78486553 neural precursor cell expressed, developmentally dow... 125 6e-29
gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa... 112 4e-25
gi|55769585 HEF-like protein [Homo sapiens] 89 5e-18
gi|182765466 FCH and double SH3 domains 2 [Homo sapiens] 65 7e-11
gi|11321634 CD2-associated protein [Homo sapiens] 58 2e-08
gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo ... 56 4e-08
gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo ... 56 4e-08
gi|224177511 sorting nexin 18 isoform c [Homo sapiens] 56 6e-08
gi|157057545 sorting nexin 18 isoform a [Homo sapiens] 56 6e-08
gi|157057543 sorting nexin 18 isoform b [Homo sapiens] 56 6e-08
gi|28875786 FCH and double SH3 domains 1 [Homo sapiens] 54 3e-07
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 53 5e-07
gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H... 53 5e-07
gi|20149528 proline-serine-threonine phosphatase interacting pro... 52 8e-07
gi|155723000 mixed lineage kinase 4 [Homo sapiens] 52 1e-06
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [... 51 2e-06
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H... 51 2e-06
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 51 2e-06
gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens] 50 2e-06
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens] 50 2e-06
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens] 50 2e-06
gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens] 50 2e-06
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 50 4e-06
>gi|239745044 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 368
Score = 774 bits (1999), Expect = 0.0
Identities = 368/368 (100%), Positives = 368/368 (100%)
Query: 1 MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60
MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL
Sbjct: 1 MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60
Query: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP
Sbjct: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180
SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ
Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180
Query: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGLGSPSFLLIYLSPAP 240
VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGLGSPSFLLIYLSPAP
Sbjct: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGLGSPSFLLIYLSPAP 240
Query: 241 ARGEPCRALTGHLSQRHWAPQLCSSGRTLRIHVEKEAVTTPEASSPSYRAVSSVVTKLSC 300
ARGEPCRALTGHLSQRHWAPQLCSSGRTLRIHVEKEAVTTPEASSPSYRAVSSVVTKLSC
Sbjct: 241 ARGEPCRALTGHLSQRHWAPQLCSSGRTLRIHVEKEAVTTPEASSPSYRAVSSVVTKLSC 300
Query: 301 KENRMYPECISGDGYSTLMREAAWDTEIACEGFAPPTAAPGTGHLGTERIAGSCVLRCST 360
KENRMYPECISGDGYSTLMREAAWDTEIACEGFAPPTAAPGTGHLGTERIAGSCVLRCST
Sbjct: 301 KENRMYPECISGDGYSTLMREAAWDTEIACEGFAPPTAAPGTGHLGTERIAGSCVLRCST 360
Query: 361 PISSRLTL 368
PISSRLTL
Sbjct: 361 PISSRLTL 368
>gi|239745060 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 353
Score = 591 bits (1523), Expect = e-169
Identities = 284/307 (92%), Positives = 285/307 (92%), Gaps = 21/307 (6%)
Query: 1 MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60
MNHLNVLAKALY NVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGI+PGNHL
Sbjct: 1 MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHL 60
Query: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP
Sbjct: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180
SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ
Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180
Query: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGLGSPSFLLIYLSPAP 240
VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGLGSPSFLLIYLSPAP
Sbjct: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGLGSPSFLLIYLSPAP 240
Query: 241 ARGEPCRALTGHLSQRHWA---------------------PQLCSSGRTLRIHVEKEAVT 279
ARGEPCRALTGHLSQRHWA PQLCSSGRTLRIHVEKEAVT
Sbjct: 241 ARGEPCRALTGHLSQRHWAPQVTEQVQPSLSTAPGDRAVFPQLCSSGRTLRIHVEKEAVT 300
Query: 280 TPEASSP 286
TPEASSP
Sbjct: 301 TPEASSP 307
>gi|239756225 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 232
Score = 452 bits (1163), Expect = e-127
Identities = 211/211 (100%), Positives = 211/211 (100%)
Query: 1 MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60
MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL
Sbjct: 1 MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60
Query: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP
Sbjct: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180
SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ
Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180
Query: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK 211
VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK
Sbjct: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK 211
>gi|239750776 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 224
Score = 452 bits (1163), Expect = e-127
Identities = 211/211 (100%), Positives = 211/211 (100%)
Query: 1 MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60
MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL
Sbjct: 1 MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60
Query: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP
Sbjct: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180
SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ
Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180
Query: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK 211
VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK
Sbjct: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK 211
>gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]
Length = 870
Score = 441 bits (1134), Expect = e-124
Identities = 206/211 (97%), Positives = 206/211 (97%)
Query: 1 MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60
MNHLNVLAKALY NVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGN L
Sbjct: 1 MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRL 60
Query: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
KILVGMYDKKPAGPGPGPPATPAQPQPGLHAP PPASQYTPMLPNTYQPQPDSVYLVPTP
Sbjct: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTP 120
Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180
SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQV PGPGGPAQDIYQ
Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQ 180
Query: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK 211
VPPSAGMGHDIYQVP SMDTRSWEGTKPPAK
Sbjct: 181 VPPSAGMGHDIYQVPPSMDTRSWEGTKPPAK 211
Score = 39.7 bits (91), Expect = 0.004
Identities = 51/185 (27%), Positives = 67/185 (36%), Gaps = 37/185 (20%)
Query: 66 MYDKKPA---GP-GPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPS 121
+YD P GP G P P + +PP++ + Y P VP
Sbjct: 266 VYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHA-----VYDVPPSVSKDVPDGP 320
Query: 122 KAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGP-AQDIYQ 180
++ Y VP PA F+K P P +P L +P P P A+D+Y
Sbjct: 321 LLREETYDVP---------PA-----FAKAKPFDPARTP---LVLAAPPPDSPPAEDVYD 363
Query: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPR-GLGSPSFLLIYLSPA 239
VPP A D+Y VP + P V R LPP G +Y P
Sbjct: 364 VPPPA---PDLYDVPPGLRRPG------PGTLYDVPRERVLPPEVADGGVVDSGVYAVPP 414
Query: 240 PARGE 244
PA E
Sbjct: 415 PAERE 419
>gi|5453680 neural precursor cell expressed, developmentally
down-regulated 9 isoform 1 [Homo sapiens]
Length = 834
Score = 134 bits (338), Expect = 1e-31
Identities = 86/217 (39%), Positives = 116/217 (53%), Gaps = 35/217 (16%)
Query: 1 MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60
M + N++A+ALY NV E +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGIVPGN +
Sbjct: 1 MKYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60
Query: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
K+L+ GP ++ QP GL Q +PN D++Y VP P
Sbjct: 61 KLLI--------GPMQETASSHEQPASGLMQQT-FGQQKLYQVPNPQAAPRDTIYQVP-P 110
Query: 121 SKAQQGLYQVP---GPSPQ--FQSPPAKQTSTFSKQTPH----------------HPFPS 159
S QG+YQVP G Q +Q PP+ Q S PH + +PS
Sbjct: 111 SYQNQGIYQVPTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPS 170
Query: 160 P-ATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVP 195
D+Y + P Q +Y +PPS+ G ++ VP
Sbjct: 171 RYQKDVYDIP--PSHTTQGVYDIPPSSAKG-PVFSVP 204
Score = 31.2 bits (69), Expect = 1.5
Identities = 33/145 (22%), Positives = 55/145 (37%), Gaps = 22/145 (15%)
Query: 82 PAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPP 141
P+ G++ +PP+S P V+ VP QG+Y +P + PP
Sbjct: 181 PSHTTQGVY-DIPPSSAKGP------------VFSVPVGEIKPQGVYDIPPTKGVYAIPP 227
Query: 142 AKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPPSA--GMGHDIYQVPSSMD 199
+ + + FP P + P G +Y +PP+ G D++ V + D
Sbjct: 228 SACRDEAGLREKDYDFPPPMRQAGRPDLRPEG----VYDIPPTCTKPAGKDLH-VKYNCD 282
Query: 200 TRSWEGTKPPAKCASVSSPRCLPPR 224
+P A+ SP PP+
Sbjct: 283 IPG--AAEPVARRHQSLSPNHPPPQ 305
>gi|215422375 neural precursor cell expressed, developmentally
down-regulated 9 isoform 3 [Homo sapiens]
Length = 834
Score = 132 bits (333), Expect = 4e-31
Identities = 85/213 (39%), Positives = 114/213 (53%), Gaps = 35/213 (16%)
Query: 5 NVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILV 64
N++A+ALY NV E +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGIVPGN +K+L+
Sbjct: 5 NLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLI 64
Query: 65 GMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124
GP ++ QP GL Q +PN D++Y VP PS
Sbjct: 65 --------GPMQETASSHEQPASGLMQQT-FGQQKLYQVPNPQAAPRDTIYQVP-PSYQN 114
Query: 125 QGLYQVP---GPSPQ--FQSPPAKQTSTFSKQTPH----------------HPFPSP-AT 162
QG+YQVP G Q +Q PP+ Q S PH + +PS
Sbjct: 115 QGIYQVPTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQK 174
Query: 163 DLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVP 195
D+Y + P Q +Y +PPS+ G ++ VP
Sbjct: 175 DVYDIP--PSHTTQGVYDIPPSSAKG-PVFSVP 204
Score = 31.2 bits (69), Expect = 1.5
Identities = 33/145 (22%), Positives = 55/145 (37%), Gaps = 22/145 (15%)
Query: 82 PAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPP 141
P+ G++ +PP+S P V+ VP QG+Y +P + PP
Sbjct: 181 PSHTTQGVY-DIPPSSAKGP------------VFSVPVGEIKPQGVYDIPPTKGVYAIPP 227
Query: 142 AKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPPSA--GMGHDIYQVPSSMD 199
+ + + FP P + P G +Y +PP+ G D++ V + D
Sbjct: 228 SACRDEAGLREKDYDFPPPMRQAGRPDLRPEG----VYDIPPTCTKPAGKDLH-VKYNCD 282
Query: 200 TRSWEGTKPPAKCASVSSPRCLPPR 224
+P A+ SP PP+
Sbjct: 283 IPG--AAEPVARRHQSLSPNHPPPQ 305
>gi|78486553 neural precursor cell expressed, developmentally
down-regulated 9 isoform 2 [Homo sapiens]
Length = 174
Score = 125 bits (314), Expect = 6e-29
Identities = 73/159 (45%), Positives = 94/159 (59%), Gaps = 15/159 (9%)
Query: 1 MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60
M + N++A+ALY NV E +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGIVPGN +
Sbjct: 1 MKYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60
Query: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
K+L+ GP ++ QP GL Q +PN D++Y VP P
Sbjct: 61 KLLI--------GPMQETASSHEQPASGLMQQT-FGQQKLYQVPNPQAAPRDTIYQVP-P 110
Query: 121 SKAQQGLYQVP---GPSPQ--FQSPPAKQTSTFSKQTPH 154
S QG+YQVP G Q +Q PP+ Q S PH
Sbjct: 111 SYQNQGIYQVPTGHGTQEQEVYQVPPSVQRSIGGTSGPH 149
>gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo
sapiens]
Length = 561
Score = 112 bits (281), Expect = 4e-25
Identities = 96/281 (34%), Positives = 123/281 (43%), Gaps = 49/281 (17%)
Query: 7 LAKALYVNVAESPDELSFRKGDIMTVLEQD-TQGLDGWWLCSLHGRQGIVPGNHLKILVG 65
LA+ALY N AESP ELSFR+GD++ VL+++ GLDGW LCSLHG+QGIVP N +K+L
Sbjct: 9 LARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLL-- 66
Query: 66 MYDKKPAGPGPGP---PATPAQPQPGLHAP-----------VPPASQYTPML---PNTYQ 108
PAGP P P PA+PAQP AP VPP ++ P
Sbjct: 67 -----PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCP 121
Query: 109 PQPDSVYLVPTPSKAQQG-------LYQVPG-----PSPQFQSPPAKQTSTFSKQTPHHP 156
P PD +Y +P S Q +Y VP PS PA + ++ P P
Sbjct: 122 PSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPP 181
Query: 157 FPSPATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVS 216
A ++P P + + G IY PS++ S A
Sbjct: 182 GEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRAS-------ALLNLYE 234
Query: 217 SPRCLPPRGLGSPSFLLIYLSP-----APARGEPCRALTGH 252
+P L G G + IY P AP EP AL H
Sbjct: 235 APEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASH 275
Score = 31.6 bits (70), Expect = 1.2
Identities = 58/232 (25%), Positives = 85/232 (36%), Gaps = 68/232 (29%)
Query: 65 GMYDKKPAGPGPGPPATP----------------AQPQPGLHAPVPPASQYTPMLPNTYQ 108
G+YD GP P P A+ P H P P+++ P
Sbjct: 251 GIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPAL 310
Query: 109 PQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVS 168
P P++ P+PS P PSP P ++ S + P P P L
Sbjct: 311 PVPEA----PSPS---------PVPSP----APGRKGSIQDR-----PLPPPPPRL---- 344
Query: 169 PGPGGP-------AQDIYQVPPSAGMGHDIYQVPSSMD--------TRSWEGTKPPAKCA 213
PG GGP +++ P AG ++ +P + + +G++PP + A
Sbjct: 345 PGYGGPKVEGDPEGREMEDDP--AGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQ-A 401
Query: 214 SVSSPRCLPPRGLGSPSFLLIYLSPAPARGEPCRALTGHLSQRHWAPQLCSS 265
P LP RG+ +P LSP GEP TG L ++ C S
Sbjct: 402 CTGDPE-LPERGMPAPQEA---LSP----GEPLVVSTGDLQLLYFYAGQCQS 445
>gi|55769585 HEF-like protein [Homo sapiens]
Length = 786
Score = 89.4 bits (220), Expect = 5e-18
Identities = 66/194 (34%), Positives = 89/194 (45%), Gaps = 22/194 (11%)
Query: 6 VLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVG 65
+LA+ALY N + DEL+F +GDI+T+LEQ +GWW C LHGRQG+ P N L+IL
Sbjct: 14 LLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTE 73
Query: 66 MYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124
+ +P P G PA + P P P P Q S P P AQ
Sbjct: 74 VAADRPCPPFLRGLEEAPASSEETYQVPTLP----RPPTPGPVYEQMRSWAEGPQPPTAQ 129
Query: 125 QGLYQVPGPSPQFQSPPAKQTSTFSKQ---TPHHP----FPSPATDLYQVSPGPGGPA-- 175
+Y+ P P P ++T +F KQ T P P+ + +Y V GP
Sbjct: 130 --VYEFPDP-PTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVL 186
Query: 176 -----QDIYQVPPS 184
Q +Y +P S
Sbjct: 187 KEPEKQQLYDIPAS 200
>gi|182765466 FCH and double SH3 domains 2 [Homo sapiens]
Length = 740
Score = 65.5 bits (158), Expect = 7e-11
Identities = 49/158 (31%), Positives = 73/158 (46%), Gaps = 12/158 (7%)
Query: 9 KALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYD 68
KALY ++ DELSF +G I+ +L ++ Q DG+W +GR G+ P +LV
Sbjct: 573 KALYDYEGQTDDELSFPEGAIIRILNKENQDDDGFWEGEFNGRIGVFP----SVLVEELS 628
Query: 69 KKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPD---SVYLVPTPSKAQQ 125
G P P P HA +PP Y P++ P PD S+Y +PS ++
Sbjct: 629 ASENGDTPWMREIQISPSPKPHASLPPLPLY-DQPPSSPYPSPDKRSSLYFPRSPSANEK 687
Query: 126 GLY-QVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPAT 162
L+ + PG S + P +++ K P P P T
Sbjct: 688 SLHAESPGFSQASRHTP---ETSYGKLRPVRAAPPPPT 722
>gi|11321634 CD2-associated protein [Homo sapiens]
Length = 639
Score = 57.8 bits (138), Expect = 2e-08
Identities = 43/159 (27%), Positives = 72/159 (45%), Gaps = 20/159 (12%)
Query: 9 KALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYD 68
+ L+ + DEL+F++G+I+ ++ ++T G GWW L+G++G+ P N + + D
Sbjct: 275 RTLFAYEGTNEDELTFKEGEIIHLISKET-GEAGWWRGELNGKEGVFPDN-FAVQINELD 332
Query: 69 KK-PAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGL 127
K P P PPA P+P L + +Y + P + + + L PSK
Sbjct: 333 KDFPKPKKPPPPAKAPAPKPEL---IAAEKKYFSLKP---EEKDEKSTLEQKPSKP---- 382
Query: 128 YQVPGPSPQFQSPPAK------QTSTFSKQTPHHPFPSP 160
P P+ +PP K + T + P P P P
Sbjct: 383 -AAPQVPPKKPTPPTKASNLLRSSGTVYPKRPEKPVPPP 420
Score = 38.9 bits (89), Expect = 0.007
Identities = 18/55 (32%), Positives = 32/55 (58%), Gaps = 3/55 (5%)
Query: 9 KALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKIL 63
K L+ + ++ DEL + GDI+ + E+ +G WW +L+ + G+ P N +K L
Sbjct: 114 KVLFEYIPQNEDELELKVGDIIDINEEVEEG---WWSGTLNNKLGLFPSNFVKEL 165
Score = 30.0 bits (66), Expect = 3.4
Identities = 15/42 (35%), Positives = 27/42 (64%), Gaps = 2/42 (4%)
Query: 20 DELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLK 61
DEL+ R G+I+ +++ + +GW L+GR+G+ P N +K
Sbjct: 16 DELTIRVGEIIRNVKKLQE--EGWLEGELNGRRGMFPDNFVK 55
>gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo
sapiens]
Length = 628
Score = 56.2 bits (134), Expect = 4e-08
Identities = 28/79 (35%), Positives = 49/79 (62%), Gaps = 2/79 (2%)
Query: 9 KALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYD 68
K ++ A++ DEL+ ++GDI+T++ +D + GWW L+GR+G+ P N +K+L ++
Sbjct: 236 KVIFPYEAQNDDELTIKEGDIVTLINKDCIDV-GWWEGELNGRRGVFPDNFVKLLPPDFE 294
Query: 69 KKPAGP-GPGPPATPAQPQ 86
K+ P P PP+ P Q
Sbjct: 295 KEGNRPKKPPPPSAPVIKQ 313
Score = 38.1 bits (87), Expect = 0.013
Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
Query: 17 ESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYDK 69
++ DEL + GDI+ V+ + +G WW L+G+ G+ P N +K L G D+
Sbjct: 75 QNDDELELKVGDIIEVVGEVEEG---WWEGVLNGKTGMFPSNFIKELSGESDE 124
>gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo
sapiens]
Length = 665
Score = 56.2 bits (134), Expect = 4e-08
Identities = 28/79 (35%), Positives = 49/79 (62%), Gaps = 2/79 (2%)
Query: 9 KALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYD 68
K ++ A++ DEL+ ++GDI+T++ +D + GWW L+GR+G+ P N +K+L ++
Sbjct: 273 KVIFPYEAQNDDELTIKEGDIVTLINKDCIDV-GWWEGELNGRRGVFPDNFVKLLPPDFE 331
Query: 69 KKPAGP-GPGPPATPAQPQ 86
K+ P P PP+ P Q
Sbjct: 332 KEGNRPKKPPPPSAPVIKQ 350
Score = 38.1 bits (87), Expect = 0.013
Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
Query: 17 ESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYDK 69
++ DEL + GDI+ V+ + +G WW L+G+ G+ P N +K L G D+
Sbjct: 112 QNDDELELKVGDIIEVVGEVEEG---WWEGVLNGKTGMFPSNFIKELSGESDE 161
Score = 35.8 bits (81), Expect = 0.063
Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
Query: 16 AESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYDKKP 71
A+ DEL+ G+I+T + ++ GWW ++GR+G+ P N ++ + K P
Sbjct: 12 AQHDDELTISVGEIITNIRKED---GGWWEGQINGRRGLFPDNFVREIKKEMKKDP 64
>gi|224177511 sorting nexin 18 isoform c [Homo sapiens]
Length = 591
Score = 55.8 bits (133), Expect = 6e-08
Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 27/145 (18%)
Query: 8 AKALYVNVAESPDELSFRKGDIMTVL-EQDTQGLDGWWLCSLHGR--QGIVPGNHLKILV 64
A+ALY +E+P E+S R+ +++++ EQD +G WL ++ R +G+ P ++++++
Sbjct: 5 ARALYDFRSENPGEISLREHEVLSLCSEQDIEG----WLEGVNSRGDRGLFPASYVQVIR 60
Query: 65 GMYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKA 123
+ PAG G PG PA A PG P+P A P +++P PD+ + P +A
Sbjct: 61 AP-EPGPAGDGGPGAPARYANVPPGGFEPLPVAP------PASFKPPPDAFQALLQPQQA 113
Query: 124 -QQGLYQVPG-----------PSPQ 136
+Q PG PSPQ
Sbjct: 114 PPPSTFQPPGAGFPYGGGALQPSPQ 138
>gi|157057545 sorting nexin 18 isoform a [Homo sapiens]
Length = 624
Score = 55.8 bits (133), Expect = 6e-08
Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 27/145 (18%)
Query: 8 AKALYVNVAESPDELSFRKGDIMTVL-EQDTQGLDGWWLCSLHGR--QGIVPGNHLKILV 64
A+ALY +E+P E+S R+ +++++ EQD +G WL ++ R +G+ P ++++++
Sbjct: 5 ARALYDFRSENPGEISLREHEVLSLCSEQDIEG----WLEGVNSRGDRGLFPASYVQVIR 60
Query: 65 GMYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKA 123
+ PAG G PG PA A PG P+P A P +++P PD+ + P +A
Sbjct: 61 AP-EPGPAGDGGPGAPARYANVPPGGFEPLPVAP------PASFKPPPDAFQALLQPQQA 113
Query: 124 -QQGLYQVPG-----------PSPQ 136
+Q PG PSPQ
Sbjct: 114 PPPSTFQPPGAGFPYGGGALQPSPQ 138
>gi|157057543 sorting nexin 18 isoform b [Homo sapiens]
Length = 628
Score = 55.8 bits (133), Expect = 6e-08
Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 27/145 (18%)
Query: 8 AKALYVNVAESPDELSFRKGDIMTVL-EQDTQGLDGWWLCSLHGR--QGIVPGNHLKILV 64
A+ALY +E+P E+S R+ +++++ EQD +G WL ++ R +G+ P ++++++
Sbjct: 5 ARALYDFRSENPGEISLREHEVLSLCSEQDIEG----WLEGVNSRGDRGLFPASYVQVIR 60
Query: 65 GMYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKA 123
+ PAG G PG PA A PG P+P A P +++P PD+ + P +A
Sbjct: 61 AP-EPGPAGDGGPGAPARYANVPPGGFEPLPVAP------PASFKPPPDAFQALLQPQQA 113
Query: 124 -QQGLYQVPG-----------PSPQ 136
+Q PG PSPQ
Sbjct: 114 PPPSTFQPPGAGFPYGGGALQPSPQ 138
>gi|28875786 FCH and double SH3 domains 1 [Homo sapiens]
Length = 690
Score = 53.5 bits (127), Expect = 3e-07
Identities = 43/153 (28%), Positives = 69/153 (45%), Gaps = 15/153 (9%)
Query: 7 LAKALYVNVAESPDELSFRKGDIMTVLEQDTQGL-DGWWLCSLHGRQGIVPGNHLKILVG 65
LA+ALY +S +ELSF +G ++ +L + G+ DG+W GR G+ P ++ L+G
Sbjct: 550 LAQALYSYTGQSAEELSFPEGALIRLLPRAQDGVDDGFWRGEFGGRVGVFPSLLVEELLG 609
Query: 66 MYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQ 125
PGPP + P+ L +P PP+ ++P P + P + L +
Sbjct: 610 ---------PPGPPEL-SDPEQMLPSPSPPS--FSPPAPTSVLDGPPAPVLPGDKALDFP 657
Query: 126 GLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFP 158
G + P + PP + P HP P
Sbjct: 658 GFLDMMAPRLRPMRPPPPPPA--KAPDPGHPDP 688
>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
sapiens]
Length = 756
Score = 52.8 bits (125), Expect = 5e-07
Identities = 45/161 (27%), Positives = 67/161 (41%), Gaps = 34/161 (21%)
Query: 9 KALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYD 68
+ L+ E+PDEL+ R+GD++ VL + T+ GWW GR+G+ P N +
Sbjct: 187 RVLFDYQPEAPDELALRRGDVVKVLSKTTED-KGWWEGECQGRRGVFPDNFVL------- 238
Query: 69 KKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQ----------PDSVYLVP 118
P PP P+ + P + ++P T P P
Sbjct: 239 -------PPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSR 291
Query: 119 TPSKAQQGL-YQVPGPSPQFQS-----PPAKQTSTFSKQTP 153
TPS+ Q L + GP+ FQS P K++ T QTP
Sbjct: 292 TPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKT---QTP 329
Score = 42.4 bits (98), Expect = 7e-04
Identities = 35/112 (31%), Positives = 51/112 (45%), Gaps = 22/112 (19%)
Query: 13 VNVAESP---DELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYDK 69
VN + SP DEL + G+I+ ++++ DGWWL +G+ G P N +++L D
Sbjct: 90 VNFSYSPEQADELKLQAGEIVEMIKEIE---DGWWLGKKNGQLGAFPSNFVELL----DS 142
Query: 70 KPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPN-TYQPQPDSVYLVPTP 120
P P G P P+ V P Q P L + Y PD + V P
Sbjct: 143 GP--PSLGNPDMPS---------VSPGPQRPPKLSSLAYDSPPDYLQTVSHP 183
>gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo
sapiens]
Length = 645
Score = 52.8 bits (125), Expect = 5e-07
Identities = 45/161 (27%), Positives = 67/161 (41%), Gaps = 34/161 (21%)
Query: 9 KALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVGMYD 68
+ L+ E+PDEL+ R+GD++ VL + T+ GWW GR+G+ P N +
Sbjct: 76 RVLFDYQPEAPDELALRRGDVVKVLSKTTED-KGWWEGECQGRRGVFPDNFVL------- 127
Query: 69 KKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQ----------PDSVYLVP 118
P PP P+ + P + ++P T P P
Sbjct: 128 -------PPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSR 180
Query: 119 TPSKAQQGL-YQVPGPSPQFQS-----PPAKQTSTFSKQTP 153
TPS+ Q L + GP+ FQS P K++ T QTP
Sbjct: 181 TPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKT---QTP 218
Score = 34.7 bits (78), Expect = 0.14
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 16/81 (19%)
Query: 41 DGWWLCSLHGRQGIVPGNHLKILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYT 100
DGWWL +G+ G P N +++L D P P G P P+ V P Q
Sbjct: 7 DGWWLGKKNGQLGAFPSNFVELL----DSGP--PSLGNPDMPS---------VSPGPQRP 51
Query: 101 PMLPN-TYQPQPDSVYLVPTP 120
P L + Y PD + V P
Sbjct: 52 PKLSSLAYDSPPDYLQTVSHP 72
>gi|20149528 proline-serine-threonine phosphatase interacting
protein 1 [Homo sapiens]
Length = 416
Score = 52.0 bits (123), Expect = 8e-07
Identities = 24/55 (43%), Positives = 36/55 (65%), Gaps = 3/55 (5%)
Query: 9 KALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKIL 63
+ALY A++PDEL GDI+ V+ +G DGWW +G++G VPG++L+ L
Sbjct: 365 RALYDYTAQNPDELDLSAGDILEVI---LEGEDGWWTVERNGQRGFVPGSYLEKL 416
>gi|155723000 mixed lineage kinase 4 [Homo sapiens]
Length = 1036
Score = 51.6 bits (122), Expect = 1e-06
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 11/83 (13%)
Query: 10 ALYVNVAESPDELSFRKGDIMTVLEQD--TQGLDGWWLCSLHGRQGIVPGNHLKILVGMY 67
ALY A DELS R+G ++ VL QD G +GWW + R GI P N++
Sbjct: 45 ALYDYEARGEDELSLRRGQLVEVLSQDAAVSGDEGWWAGQVQRRLGIFPANYV------- 97
Query: 68 DKKPAGPGPGPPATPAQPQPGLH 90
P P P P++P +H
Sbjct: 98 --APCRPAASPAPPPSRPSSPVH 118
>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
[Homo sapiens]
Length = 828
Score = 50.8 bits (120), Expect = 2e-06
Identities = 24/50 (48%), Positives = 33/50 (66%)
Query: 10 ALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNH 59
AL+ AE DELSFR+G+ +TVL +D WW +LHG++G VP N+
Sbjct: 765 ALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYVPRNY 814
Score = 40.0 bits (92), Expect = 0.003
Identities = 45/163 (27%), Positives = 58/163 (35%), Gaps = 32/163 (19%)
Query: 71 PAGPGPGPPATPAQPQP---GLHAPVPPASQY------TPMLPNTYQPQ-PDSVYLVPTP 120
P GP P T +P+P GL PV A P+ P QP P VP
Sbjct: 448 PVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPEL 507
Query: 121 SKAQQGLYQVPGP----SPQFQSPPAKQTSTFSKQ---------------TPHHPFP--S 159
+ + L ++P P Q+P T KQ P P P S
Sbjct: 508 EEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELS 567
Query: 160 PATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVPSSMDTRS 202
P T+ + GP PA +PP A + P SM+ RS
Sbjct: 568 PITEGSEARAGPPAPAPPA-PIPPPAPSQSSPPEQPQSMEMRS 609
Score = 31.2 bits (69), Expect = 1.5
Identities = 30/125 (24%), Positives = 46/125 (36%), Gaps = 9/125 (7%)
Query: 70 KPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQG--- 126
+P P PP++P P+P + + L N + S ++P +
Sbjct: 347 QPVSRIPMPPSSPQPRGAPRQRPIPLSMIFK--LQNAFWEHGASRAMLPGSPLFTRAPPP 404
Query: 127 -LYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLY---QVSPGPGGPAQDIYQVP 182
L P P PQ QS P Q + P P P+P V+ GP P ++ P
Sbjct: 405 KLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEP 464
Query: 183 PSAGM 187
G+
Sbjct: 465 EIEGL 469
>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
sapiens]
Length = 828
Score = 50.8 bits (120), Expect = 2e-06
Identities = 24/50 (48%), Positives = 33/50 (66%)
Query: 10 ALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNH 59
AL+ AE DELSFR+G+ +TVL +D WW +LHG++G VP N+
Sbjct: 765 ALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYVPRNY 814
Score = 40.0 bits (92), Expect = 0.003
Identities = 45/163 (27%), Positives = 58/163 (35%), Gaps = 32/163 (19%)
Query: 71 PAGPGPGPPATPAQPQP---GLHAPVPPASQY------TPMLPNTYQPQ-PDSVYLVPTP 120
P GP P T +P+P GL PV A P+ P QP P VP
Sbjct: 448 PVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPEL 507
Query: 121 SKAQQGLYQVPGP----SPQFQSPPAKQTSTFSKQ---------------TPHHPFP--S 159
+ + L ++P P Q+P T KQ P P P S
Sbjct: 508 EEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELS 567
Query: 160 PATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVPSSMDTRS 202
P T+ + GP PA +PP A + P SM+ RS
Sbjct: 568 PITEGSEARAGPPAPAPPA-PIPPPAPSQSSPPEQPQSMEMRS 609
Score = 31.2 bits (69), Expect = 1.5
Identities = 30/125 (24%), Positives = 46/125 (36%), Gaps = 9/125 (7%)
Query: 70 KPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQG--- 126
+P P PP++P P+P + + L N + S ++P +
Sbjct: 347 QPVSRIPMPPSSPQPRGAPRQRPIPLSMIFK--LQNAFWEHGASRAMLPGSPLFTRAPPP 404
Query: 127 -LYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLY---QVSPGPGGPAQDIYQVP 182
L P P PQ QS P Q + P P P+P V+ GP P ++ P
Sbjct: 405 KLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEP 464
Query: 183 PSAGM 187
G+
Sbjct: 465 EIEGL 469
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 50.8 bits (120), Expect = 2e-06
Identities = 58/210 (27%), Positives = 73/210 (34%), Gaps = 37/210 (17%)
Query: 68 DKKPAGPGPG-----PPATPAQPQPGLHAPVPPASQYTPMLPNTYQ----PQPDSVYLVP 118
++ P GPGPG PP P P P PP Q P P +Q PQP P
Sbjct: 43 NRGPMGPGPGQSGPKPPIPP--PPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPP 100
Query: 119 TP--SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTP-------HHPFPSPATDLYQVSP 169
P ++ + Q PGP+P S P +S P P P+P S
Sbjct: 101 PPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSA 160
Query: 170 GPGGPAQDIYQVPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPR--GLG 227
PG P PPS+G + T + PP A+V P P + G G
Sbjct: 161 PPGAPP----PTPPSSG-----------VPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPG 205
Query: 228 SPSFLLIYLSPAPARGEPCRALTGHLSQRH 257
P + P P G GH H
Sbjct: 206 GPKGGKMPGGPKPGGGPGLSTPGGHPKPPH 235
Score = 37.7 bits (86), Expect = 0.017
Identities = 38/130 (29%), Positives = 42/130 (32%), Gaps = 33/130 (25%)
Query: 71 PAGPGPGPPATP----AQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQG 126
P G GPGP TP PG P PP+S P P P VP P G
Sbjct: 142 PPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPA-AVPGPG---PG 197
Query: 127 LYQVPGP----------SPQFQSPPAKQTSTFSKQTP------------HHPFPSPATDL 164
Q PGP P+ P T + P HHP P
Sbjct: 198 PKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHP---PYHQQ 254
Query: 165 YQVSPGPGGP 174
+ P PGGP
Sbjct: 255 HHQGPPPGGP 264
>gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]
Length = 1083
Score = 50.4 bits (119), Expect = 2e-06
Identities = 38/101 (37%), Positives = 43/101 (42%), Gaps = 12/101 (11%)
Query: 75 GPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPS 134
G P TP P P P + TP P Y S Y P+P QG YQ P PS
Sbjct: 849 GTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSP----QGSYQ-PSPS 903
Query: 135 P----QFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGP 171
P Q PA +T S + +HP PSP YQ SP P
Sbjct: 904 PQSYHQVAPSPAGYQNTHSPAS-YHPTPSPMA--YQASPSP 941
>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 50.4 bits (119), Expect = 2e-06
Identities = 38/101 (37%), Positives = 43/101 (42%), Gaps = 12/101 (11%)
Query: 75 GPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPS 134
G P TP P P P + TP P Y S Y P+P QG YQ P PS
Sbjct: 853 GTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSP----QGSYQ-PSPS 907
Query: 135 P----QFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGP 171
P Q PA +T S + +HP PSP YQ SP P
Sbjct: 908 PQSYHQVAPSPAGYQNTHSPAS-YHPTPSPMA--YQASPSP 945
>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 50.4 bits (119), Expect = 2e-06
Identities = 38/101 (37%), Positives = 43/101 (42%), Gaps = 12/101 (11%)
Query: 75 GPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPS 134
G P TP P P P + TP P Y S Y P+P QG YQ P PS
Sbjct: 853 GTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSP----QGSYQ-PSPS 907
Query: 135 P----QFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGP 171
P Q PA +T S + +HP PSP YQ SP P
Sbjct: 908 PQSYHQVAPSPAGYQNTHSPAS-YHPTPSPMA--YQASPSP 945
>gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 50.4 bits (119), Expect = 2e-06
Identities = 38/101 (37%), Positives = 43/101 (42%), Gaps = 12/101 (11%)
Query: 75 GPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPS 134
G P TP P P P + TP P Y S Y P+P QG YQ P PS
Sbjct: 853 GTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSP----QGSYQ-PSPS 907
Query: 135 P----QFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGP 171
P Q PA +T S + +HP PSP YQ SP P
Sbjct: 908 PQSYHQVAPSPAGYQNTHSPAS-YHPTPSPMA--YQASPSP 945
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 49.7 bits (117), Expect = 4e-06
Identities = 57/215 (26%), Positives = 81/215 (37%), Gaps = 38/215 (17%)
Query: 55 VPGNHLKILVGMYDKKPAGPGPGP-----------------PATPAQPQPGLHAPVPP-- 95
VP H++ ++ ++P P P P P+ P+ QP LH PP
Sbjct: 241 VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP 300
Query: 96 -ASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVP-GPSPQFQSP------PAKQTST 147
+ Q P+L + PQP + P +A QG Q P G SP P PA Q++
Sbjct: 301 HSLQAGPLLQHPGPPQPFGL-----PPQASQG--QAPLGTSPAAAYPHTSLQLPASQSAL 353
Query: 148 FSKQTP-HHPFPSPATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVPSSMDTRSWEGT 206
S+Q P P P + + P P P I Q+P H + S + +
Sbjct: 354 QSQQPPREQPLPPAPLAMPHIKPPPTTP---IPQLPAPQAHKHPPHLSGPSPFSMNANLP 410
Query: 207 KPPAKCASVSSPRCLPPRGLGSPSFLLIYLSPAPA 241
PPA S PP P L+ P P+
Sbjct: 411 PPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS 445
Score = 42.7 bits (99), Expect = 5e-04
Identities = 35/116 (30%), Positives = 43/116 (37%), Gaps = 17/116 (14%)
Query: 74 PGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGP 133
P PP TP P PG P P A+ P T P+ PT + Q P
Sbjct: 197 PSSAPPGTPQLPTPG---PTPSATAVPPQGSPTASQAPNQPQ-APTAPVPHTHIQQAPAL 252
Query: 134 SPQFQSPPAKQTSTFSKQTPH-HPFPSPATDLYQVSPGPGGPAQDIYQVPPSAGMG 188
P Q PP +PH P PSP L ++ G P+ + PP G G
Sbjct: 253 HP--QRPP----------SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
Score = 39.3 bits (90), Expect = 0.006
Identities = 31/102 (30%), Positives = 40/102 (39%), Gaps = 8/102 (7%)
Query: 78 PPATPAQ--PQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPT------PSKAQQGLYQ 129
PP TP P P H P S +P N P P ++ + + PS L
Sbjct: 377 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQL 436
Query: 130 VPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGP 171
+P P SP T S+ P P P T L+QV+P P
Sbjct: 437 MPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQP 478
Score = 38.9 bits (89), Expect = 0.007
Identities = 45/165 (27%), Positives = 59/165 (35%), Gaps = 17/165 (10%)
Query: 66 MYDKKPAGPGPGPPATPAQP--QPGLHAPVP--PASQYTPMLPNTYQPQPDSVYLVPTPS 121
+ ++P P PPA A P +P P+P PA Q P+ P P S+ P
Sbjct: 353 LQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPP 412
Query: 122 KAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGP--GGPAQDIY 179
A + L + P PP Q S+ P P P Q P P P ++
Sbjct: 413 PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLH 472
Query: 180 QVPPSAGMGHDIYQVPSSMDTRSWEGTKP--PAKCASVSSPRCLP 222
QV P Q P + G P P C S S+P P
Sbjct: 473 QVAP---------QPPFAQHPFVPGGPPPITPPTCPSTSTPPAGP 508
Score = 38.1 bits (87), Expect = 0.013
Identities = 48/180 (26%), Positives = 64/180 (35%), Gaps = 33/180 (18%)
Query: 70 KPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTY---QPQPDSVYLVPTPSKAQQG 126
+P P P T Q P LH PP S + P P+ + QP S PS AQ
Sbjct: 233 QPQAPTAPVPHTHIQQAPALHPQRPP-SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPP 291
Query: 127 LYQVPGPSP-QFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPPSA 185
L+ P P Q+ P Q HP P L P Q P+A
Sbjct: 292 LHGQGPPGPHSLQAGPLLQ----------HPGPPQPFGL----PPQASQGQAPLGTSPAA 337
Query: 186 GMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGLGSPSFLLIYLSPAPARGEP 245
H Q+P+S + + +PP + + LPP L P ++ P P P
Sbjct: 338 AYPHTSLQLPASQS--ALQSQQPPRE-------QPLPPAPLAMP-----HIKPPPTTPIP 383
Score = 30.0 bits (66), Expect = 3.4
Identities = 30/113 (26%), Positives = 41/113 (36%), Gaps = 9/113 (7%)
Query: 100 TPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPS 159
+P +P+ + DS S AQQ + Q P+ Q + S+ TP P P
Sbjct: 158 SPSIPSPQDNESDS------DSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPG 211
Query: 160 PATDLYQVSPGPGGPAQDIYQVP--PSAGMGH-DIYQVPSSMDTRSWEGTKPP 209
P V P A P P+A + H I Q P+ R PP
Sbjct: 212 PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPP 264
Score = 28.9 bits (63), Expect = 7.7
Identities = 26/98 (26%), Positives = 35/98 (35%), Gaps = 15/98 (15%)
Query: 78 PPATPAQPQPGLH--APVPPASQYT-----------PMLPNTYQPQ--PDSVYLVPTPSK 122
PP + P GLH AP PP +Q+ P P+T P P + P
Sbjct: 460 PPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGA 519
Query: 123 AQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSP 160
A G G S + K+ + + P P P P
Sbjct: 520 AASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP 557
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,068,945
Number of Sequences: 37866
Number of extensions: 1485355
Number of successful extensions: 11322
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 234
Number of HSP's successfully gapped in prelim test: 974
Number of HSP's that attempted gapping in prelim test: 6767
Number of HSP's gapped (non-prelim): 3712
length of query: 368
length of database: 18,247,518
effective HSP length: 104
effective length of query: 264
effective length of database: 14,309,454
effective search space: 3777695856
effective search space used: 3777695856
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.