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Search of human proteins with 116268103
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116268103 zinc finger, FYVE domain containing 19 [Homo
sapiens]
(471 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116268103 zinc finger, FYVE domain containing 19 [Homo sapiens] 965 0.0
gi|4758528 hepatocyte growth factor-regulated tyrosine kinase su... 57 3e-08
gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens] 52 1e-06
gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens] 52 1e-06
gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Hom... 52 2e-06
gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo... 51 2e-06
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 51 3e-06
gi|50557648 zinc finger, FYVE domain containing 27 isoform c [Ho... 50 3e-06
gi|50557646 zinc finger, FYVE domain containing 27 isoform a [Ho... 50 3e-06
gi|50557644 zinc finger, FYVE domain containing 27 isoform b [Ho... 50 3e-06
gi|217272865 myotubularin related protein 4 [Homo sapiens] 50 4e-06
gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Hom... 49 8e-06
gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Ho... 49 8e-06
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 49 8e-06
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 49 1e-05
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 49 1e-05
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 49 1e-05
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 49 1e-05
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 49 1e-05
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 48 2e-05
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 45 1e-04
gi|24797153 faciogenital dysplasia protein [Homo sapiens] 45 2e-04
gi|194353964 coiled-coil domain containing 157 [Homo sapiens] 44 2e-04
gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens] 44 2e-04
gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens] 44 2e-04
gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens] 44 4e-04
gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform... 43 5e-04
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora... 42 0.002
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens] 41 0.002
gi|126723390 ankyrin repeat domain 24 [Homo sapiens] 41 0.003
>gi|116268103 zinc finger, FYVE domain containing 19 [Homo sapiens]
Length = 471
Score = 965 bits (2495), Expect = 0.0
Identities = 471/471 (100%), Positives = 471/471 (100%)
Query: 1 MNYDSQQPPLPPLPYAGCRRASGFPALGRGGTVPVGVWGGAGQGREGRSWGEGPRGPGLG 60
MNYDSQQPPLPPLPYAGCRRASGFPALGRGGTVPVGVWGGAGQGREGRSWGEGPRGPGLG
Sbjct: 1 MNYDSQQPPLPPLPYAGCRRASGFPALGRGGTVPVGVWGGAGQGREGRSWGEGPRGPGLG 60
Query: 61 RRDLSSADPAVLGATMESRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNT 120
RRDLSSADPAVLGATMESRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNT
Sbjct: 61 RRDLSSADPAVLGATMESRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNT 120
Query: 121 QQKVCKQCHEVLTRGSSANASKWSPPQNYKKRVAALEAKQKPSTSQSQGLTRQDQMIAER 180
QQKVCKQCHEVLTRGSSANASKWSPPQNYKKRVAALEAKQKPSTSQSQGLTRQDQMIAER
Sbjct: 121 QQKVCKQCHEVLTRGSSANASKWSPPQNYKKRVAALEAKQKPSTSQSQGLTRQDQMIAER 180
Query: 181 LARLRQENKPKLVPSQAEIEARLAALKDERQGSIPSTQEMEARLAALQGRVLPSQTPQPA 240
LARLRQENKPKLVPSQAEIEARLAALKDERQGSIPSTQEMEARLAALQGRVLPSQTPQPA
Sbjct: 181 LARLRQENKPKLVPSQAEIEARLAALKDERQGSIPSTQEMEARLAALQGRVLPSQTPQPA 240
Query: 241 HHTPDTRTQAQQTQDLLTQLAAEVAIDESWKGGGPAASLQNDLNQGGPGSTNSKRQANWS 300
HHTPDTRTQAQQTQDLLTQLAAEVAIDESWKGGGPAASLQNDLNQGGPGSTNSKRQANWS
Sbjct: 241 HHTPDTRTQAQQTQDLLTQLAAEVAIDESWKGGGPAASLQNDLNQGGPGSTNSKRQANWS 300
Query: 301 LEEEKSRLLAEAALELREENTRQERILALAKRLAMLRGQDPERVTLQDYRLPDSDDDEDE 360
LEEEKSRLLAEAALELREENTRQERILALAKRLAMLRGQDPERVTLQDYRLPDSDDDEDE
Sbjct: 301 LEEEKSRLLAEAALELREENTRQERILALAKRLAMLRGQDPERVTLQDYRLPDSDDDEDE 360
Query: 361 ETAIQRVLQQLTEEASLDEASGFNIPAEQASRPWTQPRGAEPEAQDVDPRPEAEEEELPW 420
ETAIQRVLQQLTEEASLDEASGFNIPAEQASRPWTQPRGAEPEAQDVDPRPEAEEEELPW
Sbjct: 361 ETAIQRVLQQLTEEASLDEASGFNIPAEQASRPWTQPRGAEPEAQDVDPRPEAEEEELPW 420
Query: 421 CCICNEDATLRCAGCDGDLFCARCFREGHDAFELKEHQTSAYSPPRAGQEH 471
CCICNEDATLRCAGCDGDLFCARCFREGHDAFELKEHQTSAYSPPRAGQEH
Sbjct: 421 CCICNEDATLRCAGCDGDLFCARCFREGHDAFELKEHQTSAYSPPRAGQEH 471
>gi|4758528 hepatocyte growth factor-regulated tyrosine kinase
substrate [Homo sapiens]
Length = 777
Score = 57.4 bits (137), Expect = 3e-08
Identities = 42/183 (22%), Positives = 79/183 (43%), Gaps = 20/183 (10%)
Query: 80 CYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTG-NTQQKVCKQCHEVLTRGSSA 138
C+ C V+F + +++ C+ CG+ FC C S + +P+ G + +VC+ C+E L R +
Sbjct: 166 CHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNRKAEG 225
Query: 139 NASKWS--PPQNYKKRVAALEAKQKPSTSQSQGLTRQD---------QMIAERLARLRQE 187
A+ + PP+ ++ + Q P L ++ Q AE RLRQ+
Sbjct: 226 KATSTTELPPEYLTSPLS--QQSQLPPKRDETALQEEEELQLALALSQSEAEEKERLRQK 283
Query: 188 N------KPKLVPSQAEIEARLAALKDERQGSIPSTQEMEARLAALQGRVLPSQTPQPAH 241
+ K + +PS + + S P ++++ LA R + + A
Sbjct: 284 STYTSYPKAEPMPSASSAPPASSLYSSPVNSSAPLAEDIDPELARYLNRNYWEKKQEEAR 343
Query: 242 HTP 244
+P
Sbjct: 344 KSP 346
>gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens]
Length = 887
Score = 52.0 bits (123), Expect = 1e-06
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
Query: 80 CYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNTQQ-KVCKQCH 129
C C FT+ ++++ C++CG+ FCS C S SA +PR G + +VC C+
Sbjct: 823 CTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCY 873
>gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens]
Length = 1430
Score = 52.0 bits (123), Expect = 1e-06
Identities = 34/138 (24%), Positives = 58/138 (42%), Gaps = 11/138 (7%)
Query: 64 LSSADPAVLGATMESRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNTQQK 123
L S P + T + C C +FTL + + C+ CG+ C C S + N +
Sbjct: 1212 LGSKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPAR 1271
Query: 124 VCKQCHEVLTRGSSANASKWSPPQNYKKRVAALEA---------KQK--PSTSQSQGLTR 172
VC+ C + L + ++ + P N+K +AL + KQK P+ +
Sbjct: 1272 VCEHCFQELQKLDHQHSPRIGSPGNHKSPSSALSSVLHSIPSGRKQKKIPAALKEVSANT 1331
Query: 173 QDQMIAERLARLRQENKP 190
+D ++ L R + KP
Sbjct: 1332 EDSSMSGYLYRSKGNKKP 1349
>gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Homo
sapiens]
Length = 1425
Score = 51.6 bits (122), Expect = 2e-06
Identities = 28/105 (26%), Positives = 43/105 (40%), Gaps = 8/105 (7%)
Query: 64 LSSADPAVLGATMESRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNTQQK 123
L P + + C C +FT K+ + C+ CG+ FC+ C S + + +
Sbjct: 689 LGEVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEAR 748
Query: 124 VCKQCHEVLTRGSS----ANASKWSP----PQNYKKRVAALEAKQ 160
VC CH VL + +AS SP P Y + L+ Q
Sbjct: 749 VCVICHSVLMNAQAWENMMSASSQSPNPNNPAEYCSTIPPLQQAQ 793
>gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo
sapiens]
Length = 762
Score = 51.2 bits (121), Expect = 2e-06
Identities = 21/72 (29%), Positives = 32/72 (44%)
Query: 64 LSSADPAVLGATMESRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNTQQK 123
L P + + C C +FT K+ + C+ CG+ FC+ C S + + +
Sbjct: 689 LGEVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEAR 748
Query: 124 VCKQCHEVLTRG 135
VC CH VL G
Sbjct: 749 VCVICHSVLMNG 760
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens]
Length = 1478
Score = 50.8 bits (120), Expect = 3e-06
Identities = 39/174 (22%), Positives = 69/174 (39%), Gaps = 19/174 (10%)
Query: 66 SADPAVLGATMESRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNTQQKVC 125
SA+ LG T + C C +F+ + + C+ CGR FC C + + + + G +++ C
Sbjct: 1165 SAEERWLGDTEANHCLDCKREFSWMVRRHHCRICGRIFCYYCCN-NYVLSKHGGKKERCC 1223
Query: 126 KQCHEVLTRGSSANASKWSPPQNYKKRVAALEAKQKPSTSQSQGLTRQ---------DQM 176
+ C + L+ G + S S + A A P + QG D +
Sbjct: 1224 RACFQKLSEGPGSPDSSGSGTSQGEPSPALSPASPGPQATGGQGANTDYRPPDDAVFDII 1283
Query: 177 IAERLARLRQENK---------PKLVPSQAEIEARLAALKDERQGSIPSTQEME 221
E L ++++ L P+ AE + +L E +P Q+ E
Sbjct: 1284 TDEELCQIQESGSSLPETPTETDSLDPNAAEQDTTSTSLTPEDTEDMPVGQDSE 1337
>gi|50557648 zinc finger, FYVE domain containing 27 isoform c [Homo
sapiens]
Length = 404
Score = 50.4 bits (119), Expect = 3e-06
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 7/62 (11%)
Query: 80 CYGCAVKFTLFKKEYGCKNCGRAFCSGCLSF-------SAAVPRTGNTQQKVCKQCHEVL 132
C GC+ F++ KK C NCG +FCS C SF A P VC C++ L
Sbjct: 343 CTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTL 402
Query: 133 TR 134
++
Sbjct: 403 SK 404
>gi|50557646 zinc finger, FYVE domain containing 27 isoform a [Homo
sapiens]
Length = 416
Score = 50.4 bits (119), Expect = 3e-06
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 7/62 (11%)
Query: 80 CYGCAVKFTLFKKEYGCKNCGRAFCSGCLSF-------SAAVPRTGNTQQKVCKQCHEVL 132
C GC+ F++ KK C NCG +FCS C SF A P VC C++ L
Sbjct: 355 CTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTL 414
Query: 133 TR 134
++
Sbjct: 415 SK 416
>gi|50557644 zinc finger, FYVE domain containing 27 isoform b [Homo
sapiens]
Length = 411
Score = 50.4 bits (119), Expect = 3e-06
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 7/62 (11%)
Query: 80 CYGCAVKFTLFKKEYGCKNCGRAFCSGCLSF-------SAAVPRTGNTQQKVCKQCHEVL 132
C GC+ F++ KK C NCG +FCS C SF A P VC C++ L
Sbjct: 350 CTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTL 409
Query: 133 TR 134
++
Sbjct: 410 SK 411
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 50.1 bits (118), Expect = 4e-06
Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
Query: 76 MESRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVP-RTGNTQQKVCKQCHE 130
M S CY C +F L K+ + C+NCG FC+GC +P + VC C+E
Sbjct: 1116 MASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCYE 1171
>gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Homo
sapiens]
Length = 1366
Score = 49.3 bits (116), Expect = 8e-06
Identities = 20/69 (28%), Positives = 31/69 (44%)
Query: 64 LSSADPAVLGATMESRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNTQQK 123
L P + + C C +FT K+ + C+ CG+ FC+ C S + + +
Sbjct: 689 LGEVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEAR 748
Query: 124 VCKQCHEVL 132
VC CH VL
Sbjct: 749 VCVICHSVL 757
>gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Homo
sapiens]
Length = 281
Score = 49.3 bits (116), Expect = 8e-06
Identities = 18/51 (35%), Positives = 33/51 (64%), Gaps = 1/51 (1%)
Query: 80 CYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTG-NTQQKVCKQCH 129
C GC+V+F+L ++ + C+NCG+ FC C F + + R ++ +VC+ C+
Sbjct: 215 CSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 49.3 bits (116), Expect = 8e-06
Identities = 18/51 (35%), Positives = 33/51 (64%), Gaps = 1/51 (1%)
Query: 80 CYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTG-NTQQKVCKQCH 129
C GC+V+F+L ++ + C+NCG+ FC C F + + R ++ +VC+ C+
Sbjct: 3460 CSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 3510
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 48.9 bits (115), Expect = 1e-05
Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Query: 76 MESRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNTQ-QKVCKQCHEVLTR 134
+ + CY C F L +++ C+NCG FCS C + VP + +VCK C+ L
Sbjct: 1084 LAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCYSSLHP 1143
Query: 135 GSSA 138
SS+
Sbjct: 1144 TSSS 1147
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 48.9 bits (115), Expect = 1e-05
Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Query: 76 MESRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNTQ-QKVCKQCHEVLTR 134
+ + CY C F L +++ C+NCG FCS C + VP + +VCK C+ L
Sbjct: 1121 LAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCYSSLHP 1180
Query: 135 GSSA 138
SS+
Sbjct: 1181 TSSS 1184
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 48.5 bits (114), Expect = 1e-05
Identities = 21/64 (32%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Query: 78 SRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNTQQKVCKQCHEVLTRGSS 137
+ C C +F++ ++++ C+NCG FC+ C S A+P + +VC CH +L + S
Sbjct: 538 THCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALP-SYPKPVRVCDSCHTLLLQRCS 596
Query: 138 ANAS 141
+ AS
Sbjct: 597 STAS 600
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 48.5 bits (114), Expect = 1e-05
Identities = 21/64 (32%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Query: 78 SRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNTQQKVCKQCHEVLTRGSS 137
+ C C +F++ ++++ C+NCG FC+ C S A+P + +VC CH +L + S
Sbjct: 538 THCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALP-SYPKPVRVCDSCHTLLLQRCS 596
Query: 138 ANAS 141
+ AS
Sbjct: 597 STAS 600
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 48.5 bits (114), Expect = 1e-05
Identities = 21/64 (32%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Query: 78 SRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNTQQKVCKQCHEVLTRGSS 137
+ C C +F++ ++++ C+NCG FC+ C S A+P + +VC CH +L + S
Sbjct: 646 THCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALP-SYPKPVRVCDSCHTLLLQRCS 704
Query: 138 ANAS 141
+ AS
Sbjct: 705 STAS 708
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 48.1 bits (113), Expect = 2e-05
Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 6/82 (7%)
Query: 63 DLSSADPAVLGATM-----ESRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRT 117
D+ A+ A+ G + C C +F+L K+++ C+NCG FC+ C +P +
Sbjct: 559 DIKEANKALQGLVWLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLP-S 617
Query: 118 GNTQQKVCKQCHEVLTRGSSAN 139
+VC CH +L + S+N
Sbjct: 618 SPKPVRVCDSCHALLIQRCSSN 639
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 45.1 bits (105), Expect = 1e-04
Identities = 42/205 (20%), Positives = 79/205 (38%), Gaps = 21/205 (10%)
Query: 80 CYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNT-QQKVCKQCHEV-LTRGSS 137
CY C+ KFT F++ + C+ CG+ FCS C + G T + C C ++ L+ S
Sbjct: 164 CYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHS 223
Query: 138 ANASKWSPPQNYKKRVAALEAKQKPSTSQ--------SQGLTRQDQMIAERLARLRQENK 189
+++ N A + PS + S+ + +D + + L N
Sbjct: 224 TDSNSIGEDLNALSDSACSVSVLDPSEPRTPVGSRKASRNIFLEDDLAWQSLIHPDSSNT 283
Query: 190 PKLVPSQAEIEARLAALKDERQGSIPSTQEMEARLAALQ---GRVLPSQTPQPAHHTPDT 246
P + RL +++++ S + +L ++PS + T
Sbjct: 284 P--------LSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSYETSVSPQANRT 335
Query: 247 RTQAQQTQDLLTQLAAEVAIDESWK 271
+ + T+D L V + + WK
Sbjct: 336 YVRTETTEDERKILLDSVQLKDLWK 360
>gi|24797153 faciogenital dysplasia protein [Homo sapiens]
Length = 961
Score = 44.7 bits (104), Expect = 2e-04
Identities = 31/117 (26%), Positives = 48/117 (41%), Gaps = 10/117 (8%)
Query: 54 PRGPGLGRRDLSSADPAVLGATMESRCYGCAVKF-TLFKKEYGCKNCGRAFCSGCLSFSA 112
P P + DL P + + C C F ++ K+ + CK CG C C F A
Sbjct: 713 PNSPNV---DLGKRAPTPIREKEVTMCMRCQEPFNSITKRRHHCKACGHVVCGKCSEFRA 769
Query: 113 AVPRTGNTQQKVCKQCHEVL--TRGSSANASKWSPPQNYKKRVAALEAKQKPSTSQS 167
+ N +VC C+ L GSS S+ +P ++R + LE + + S
Sbjct: 770 RLVYDNNRSNRVCTDCYVALHGVPGSSPACSQHTP----QRRRSILEKQASVAAENS 822
>gi|194353964 coiled-coil domain containing 157 [Homo sapiens]
Length = 752
Score = 44.3 bits (103), Expect = 2e-04
Identities = 67/311 (21%), Positives = 120/311 (38%), Gaps = 79/311 (25%)
Query: 104 CSGCLSFSAAVPRTGNTQQKVCKQCHEVLTRGS---------------SANASKWSPPQN 148
C C S ++ + G +C+ + + G +A +W+ Q
Sbjct: 221 CDACASVQGSLQKVGKVVISLCQSQNLPSSLGQFQQLVQDSMGLRPLPAATVGRWAAEQR 280
Query: 149 -----YKKRVAALEAKQKPSTSQSQGLTRQDQMIAERL-----ARLRQ------------ 186
K V AL A+ + + Q GL +Q + + L AR RQ
Sbjct: 281 KDLTRLSKHVEALRAQLEEAEGQKDGLRKQAGKLEQALKQEQGARRRQAEEDEQCLSEWE 340
Query: 187 ENKPKLVPSQAEIEARLAALKDERQGSIPSTQEMEARLAALQGRVLPSQTPQPAHHTPDT 246
+K +L+ ++++ ++A L+ E + STQ +EA+ LQ +
Sbjct: 341 HDKQQLLTETSDLKTKMATLERELKQQRESTQAVEAKAQQLQ---------EEGERRAAA 391
Query: 247 RTQAQQTQDLLTQLAAEVAIDESWKGGGPAASLQNDLNQGGPGSTNSKRQANWS---LEE 303
Q QQ ++ + QL A+V + L L G +Q W+ L++
Sbjct: 392 ERQVQQLEEQVQQLEAQVQL------------LVGRLEGAG-------QQVCWASTELDK 432
Query: 304 EKSRLLAEAALELREENTRQERILALAKRLAMLRGQDPERVTLQDYRLPDSDDDEDEETA 363
EK+R+ + +R + + Q + AL K+L L D ER L+ D+ E +
Sbjct: 433 EKARVDS----MVRHQESLQAKQRALLKQLDSL---DQEREELRG----SLDEAEAQRAR 481
Query: 364 IQRVLQQLTEE 374
++ LQ E+
Sbjct: 482 VEEQLQSEREQ 492
>gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 44.3 bits (103), Expect = 2e-04
Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 64 LSSADPAVLGATMESRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNTQQK 123
L P + + C C VKFT K+ + C+ CG+ FC C + + + +
Sbjct: 737 LGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYL-EKEAR 795
Query: 124 VCKQCHEVLTRGSS 137
VC C+E +++ +
Sbjct: 796 VCVVCYETISKAQA 809
>gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 44.3 bits (103), Expect = 2e-04
Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 64 LSSADPAVLGATMESRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNTQQK 123
L P + + C C VKFT K+ + C+ CG+ FC C + + + +
Sbjct: 737 LGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYL-EKEAR 795
Query: 124 VCKQCHEVLTRGSS 137
VC C+E +++ +
Sbjct: 796 VCVVCYETISKAQA 809
>gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens]
Length = 2539
Score = 43.5 bits (101), Expect = 4e-04
Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 11/88 (12%)
Query: 77 ESRCYGCAVK-FTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTGNTQQKVCKQCH------ 129
ES C C + FT+F + + C+ CGR CS C + V +VC QC+
Sbjct: 1815 ESICMVCCREHFTMFNRRHHCRRCGRLVCSSCSTKKMVVEGCRENPARVCDQCYSYCNKD 1874
Query: 130 ---EVLTRGSSANASK-WSPPQNYKKRV 153
E + + ++SK SPP ++ RV
Sbjct: 1875 VPEEPSEKPEALDSSKNESPPYSFVVRV 1902
>gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform 1
[Homo sapiens]
Length = 1170
Score = 43.1 bits (100), Expect = 5e-04
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Query: 78 SRCYGCAVKFTLFKKEYGCKNCGRAFCSGCLSFSAAVPRTG-NTQQKVCKQCHEVLTRG 135
S CY C +F + +++ C++CGR C C + + + N +VC C +VLT G
Sbjct: 1109 SYCYECTARFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICFDVLTLG 1167
>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 2 [Homo
sapiens]
Length = 1651
Score = 41.6 bits (96), Expect = 0.002
Identities = 65/270 (24%), Positives = 112/270 (41%), Gaps = 37/270 (13%)
Query: 162 PSTSQSQGLTRQDQMIAERLARLRQENKPKLVPSQAEIEARLAALKDERQGSIPSTQEME 221
P ++ GL AER R R+E+ Q E A L++ER+ +E E
Sbjct: 1391 PPSANQIGLPSAQVAAAER--RKREEH-------QRWYEKEKARLEEERERK---RREQE 1438
Query: 222 ARLAALQGRVLPSQTPQPAHHTPDTRTQAQQTQDLLTQLAAEVAIDESWKGGGPAASLQN 281
+L ++ +Q+ PA +P T Q + + Q E I E P +
Sbjct: 1439 RKLGQMR-----TQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERR 1493
Query: 282 DLN-------QGGPGSTNS----KRQANWSLEEEKSRLLAEA-ALELREENTRQERILAL 329
DL + G + S KR A LE+++ + + + E++E ++ +R
Sbjct: 1494 DLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEE 1553
Query: 330 AKRLAMLRGQDPERVTLQDYRLPDSDDDEDEETAIQR--VLQQL-TEEASLDEASGFNIP 386
+ RL L + + LQ+ + D DD+E+E+ + ++Q+L E + DE
Sbjct: 1554 SDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQ 1613
Query: 387 AEQASRPWTQPRGAEPEAQDVDPRPEAEEE 416
E+ + R AE A+ + R EEE
Sbjct: 1614 LEEMRK-----REAEDRARQEEERRRQEEE 1638
>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
Length = 1170
Score = 41.2 bits (95), Expect = 0.002
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 10/73 (13%)
Query: 76 MESRCYGCAVKFTLFKKEYGCK---------NCGRAFCSGCLSFSAAVPRTGNTQ-QKVC 125
+ + CY C F L +++ C+ NCG FCS C + VP + +VC
Sbjct: 1084 LAAHCYACDSAFWLASRKHHCRDTDRVDQTWNCGNVFCSSCCNQKVPVPSQQLFEPSRVC 1143
Query: 126 KQCHEVLTRGSSA 138
K C+ L SS+
Sbjct: 1144 KSCYSSLHPTSSS 1156
>gi|126723390 ankyrin repeat domain 24 [Homo sapiens]
Length = 1146
Score = 40.8 bits (94), Expect = 0.003
Identities = 68/277 (24%), Positives = 111/277 (40%), Gaps = 22/277 (7%)
Query: 159 KQKPSTSQSQGLTRQDQMIAERLARLRQENKPKLVPSQAEIEARLAALKDERQGS---IP 215
++ P S L RQ Q + + L RQE K L +++RL+ L++ER+ + +
Sbjct: 352 QESPEASSLHILERQVQELQQLLVE-RQEEKESLGREVESLQSRLSLLENERENTSYDVT 410
Query: 216 STQEMEARLAALQG-RVLPSQ--TPQPAHHTPDTRTQAQQTQDLLTQLAAEVAIDESWKG 272
+ Q+ E L L G VL S+ +P H + Q +L +V I E+++
Sbjct: 411 TLQDEEGELPDLPGAEVLLSRQLSPSAQEHLASLQEQVAVLTRQNQELMEKVQILENFEK 470
Query: 273 GGPAASLQNDLNQGGPGSTNSKRQANWSLEEEKSRLLAEAALELREENTRQ---ERILAL 329
++ L + P + +A + ++ R AEA LR++ TR+ E A
Sbjct: 471 DETQMEVEA-LAEVIPLALYDSLRAEF---DQLRRQHAEALQALRQQETREVPREEGAAC 526
Query: 330 AKRL---AMLRGQDPERVTLQDYRLPDSD----DDEDEETAIQRVLQQLTEEASLDEASG 382
+ A P + L P++ + DEE A ++ T EA A
Sbjct: 527 GESEVAGATATKNGPTHMELNGSVAPETKVNGAETIDEEAAGDETMEARTMEAEATGAEA 586
Query: 383 FNIPAEQASRPWTQPRGAEPEAQDVDPRPEAEEEELP 419
A A T+P GAE + EA E P
Sbjct: 587 TGAEATGAKVTETKPTGAEVREMET-TEEEANMETKP 622
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,064,848
Number of Sequences: 37866
Number of extensions: 1105671
Number of successful extensions: 10410
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 458
Number of HSP's that attempted gapping in prelim test: 7953
Number of HSP's gapped (non-prelim): 2832
length of query: 471
length of database: 18,247,518
effective HSP length: 106
effective length of query: 365
effective length of database: 14,233,722
effective search space: 5195308530
effective search space used: 5195308530
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.