BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239741720 PREDICTED: hypothetical protein XP_002342298 [Homo sapiens] (248 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239741720 PREDICTED: hypothetical protein XP_002342298 [Homo ... 543 e-155 gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ... 373 e-104 gi|238859658 LIM and senescent cell antigen-like domains 2 isofo... 320 9e-88 gi|238776786 LIM and senescent cell antigen-like domains 2 isofo... 320 9e-88 gi|40804748 LIM and senescent cell antigen-like domains 2 isofor... 320 9e-88 gi|238776788 LIM and senescent cell antigen-like domains 2 isofo... 317 5e-87 gi|15743548 LIM and senescent cell antigen-like domains 3 [Homo ... 241 3e-64 gi|239758027 PREDICTED: similar to LIM and senescent cell antige... 208 3e-54 gi|170932518 paxillin isoform 3 [Homo sapiens] 94 8e-20 gi|170932516 paxillin isoform 2 [Homo sapiens] 94 8e-20 gi|170932514 paxillin isoform 1 [Homo sapiens] 94 8e-20 gi|109638745 transforming growth factor beta 1 induced transcrip... 92 5e-19 gi|21361591 transforming growth factor beta 1 induced transcript... 92 5e-19 gi|58530845 zyxin [Homo sapiens] 91 7e-19 gi|4508047 zyxin [Homo sapiens] 91 7e-19 gi|221316659 leupaxin isoform 1 [Homo sapiens] 91 1e-18 gi|4758670 leupaxin isoform 2 [Homo sapiens] 91 1e-18 gi|7657307 LIM domains containing 1 [Homo sapiens] 89 4e-18 gi|14249622 ajuba isoform 1 [Homo sapiens] 86 3e-17 gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens] 80 2e-15 gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens] 80 2e-15 gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens] 80 2e-15 gi|30410801 activator of cAMP-responsive element modulator (CREM... 80 2e-15 gi|122937269 Wilms tumor 1 interacting protein [Homo sapiens] 80 2e-15 gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 79 5e-15 gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens] 79 5e-15 gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 79 5e-15 gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 79 5e-15 gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] 79 5e-15 gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] 79 5e-15 >gi|239741720 PREDICTED: hypothetical protein XP_002342298 [Homo sapiens] Length = 248 Score = 543 bits (1400), Expect = e-155 Identities = 248/248 (100%), Positives = 248/248 (100%) Query: 1 MAFSGRARPCIIPENEEIPRAALNTVHEANGTEDERAVSKLQRRHSDVKVYKEFCDFYAK 60 MAFSGRARPCIIPENEEIPRAALNTVHEANGTEDERAVSKLQRRHSDVKVYKEFCDFYAK Sbjct: 1 MAFSGRARPCIIPENEEIPRAALNTVHEANGTEDERAVSKLQRRHSDVKVYKEFCDFYAK 60 Query: 61 FNMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKY 120 FNMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKY Sbjct: 61 FNMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKY 120 Query: 121 CEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLC 180 CEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLC Sbjct: 121 CEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLC 180 Query: 181 RPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQEGSDCRCTGAER 240 RPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQEGSDCRCTGAER Sbjct: 181 RPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQEGSDCRCTGAER 240 Query: 241 GAILPAMP 248 GAILPAMP Sbjct: 241 GAILPAMP 248 >gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo sapiens] Length = 325 Score = 373 bits (957), Expect = e-104 Identities = 165/167 (98%), Positives = 166/167 (99%) Query: 63 MANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 122 MANALASATCERCKGGFAPAE IVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE Sbjct: 1 MANALASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 60 Query: 123 HDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP 182 HDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP Sbjct: 61 HDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP 120 Query: 183 CHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQE 229 CHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCG+E Sbjct: 121 CHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKE 167 Score = 73.9 bits (180), Expect = 1e-13 Identities = 35/103 (33%), Positives = 53/103 (51%), Gaps = 1/103 (0%) Query: 85 IVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRV 144 +VN+ G+ +H + FVCA+C + F YE +G YCE + LF C C I G V Sbjct: 204 VVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDV 263 Query: 145 IKAMNNSWHPECFRCDLCQEVLA-DIGFVKNAGRHLCRPCHNR 186 + A+N +W CF C C L FV+ + +C+ C+ + Sbjct: 264 VSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306 Score = 60.5 bits (145), Expect = 1e-09 Identities = 41/163 (25%), Positives = 65/163 (39%), Gaps = 8/163 (4%) Query: 64 ANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEH 123 A L C++C + ++ N + YH F CA C ++ E +G YC Sbjct: 127 ARGLGKYICQKCHA-IIDEQPLIFKN-DPYHPDHFNCANCGKELTADA-RELKGELYCLP 183 Query: 124 DFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 183 + P C C I GRV+ AM WH E F C C++ + G C Sbjct: 184 CHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETH 243 Query: 184 HNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 226 +N+ L +C C+ +I+ + N + + F C+ C Sbjct: 244 YNQ-----LFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTC 281 Score = 36.2 bits (82), Expect = 0.027 Identities = 25/107 (23%), Positives = 46/107 (42%), Gaps = 7/107 (6%) Query: 128 LFAPCCHQC--GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHN 185 L + C +C G +++ + +H +CF C C + + F + GR C H+ Sbjct: 5 LASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE--HD 62 Query: 186 REKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQEGSD 232 + L C +C I + + N+ +HP+ F C C + +D Sbjct: 63 FQM---LFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLAD 106 >gi|238859658 LIM and senescent cell antigen-like domains 2 isoform 1 [Homo sapiens] Length = 363 Score = 320 bits (819), Expect = 9e-88 Identities = 135/168 (80%), Positives = 153/168 (91%) Query: 62 NMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYC 121 NM++ALA+A C+RC+ F+PAE IVNSNGELYHE CFVCAQCF+ FPEGLFYEFEGRKYC Sbjct: 27 NMSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYC 86 Query: 122 EHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCR 181 EHDFQMLFAPCC CGEFIIGRVIKAMNN+WHP CFRC+LC LAD+GFVKNAGRHLCR Sbjct: 87 EHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCR 146 Query: 182 PCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQE 229 PCHNREKA+GLGKYICQ+CH +IDEQPL+F++D YHPDHFNC +CG+E Sbjct: 147 PCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKE 194 Score = 74.7 bits (182), Expect = 7e-14 Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 1/103 (0%) Query: 85 IVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRV 144 +VN+ G+ +H + FVCA+C + F YE +G YCE + LF C+ C I G V Sbjct: 231 VVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV 290 Query: 145 IKAMNNSWHPECFRCDLCQEVLA-DIGFVKNAGRHLCRPCHNR 186 + A+N +W CF C C L FV+ + +C+ C+ + Sbjct: 291 VSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333 Score = 59.7 bits (143), Expect = 2e-09 Identities = 40/166 (24%), Positives = 62/166 (37%), Gaps = 8/166 (4%) Query: 64 ANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEH 123 A L C+RC E + + YH F C C ++ E +G YC Sbjct: 154 AKGLGKYICQRCH--LVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLP 210 Query: 124 DFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 183 + P C C I GRV+ A+ WH E F C C++ + G C Sbjct: 211 CHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETH 270 Query: 184 HNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQE 229 +N+ L +C C +I+ + N + F+C+ C + Sbjct: 271 YNQ-----LFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSK 311 Score = 34.3 bits (77), Expect = 0.10 Identities = 23/90 (25%), Positives = 36/90 (40%), Gaps = 5/90 (5%) Query: 143 RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHA 202 R++ + +H CF C C + F + GR C H+ + L C C Sbjct: 49 RIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE--HDFQM---LFAPCCGSCGE 103 Query: 203 IIDEQPLIFKNDPYHPDHFNCANCGQEGSD 232 I + + N+ +HP F C C E +D Sbjct: 104 FIIGRVIKAMNNNWHPGCFRCELCDVELAD 133 >gi|238776786 LIM and senescent cell antigen-like domains 2 isoform 3 [Homo sapiens] Length = 341 Score = 320 bits (819), Expect = 9e-88 Identities = 135/168 (80%), Positives = 153/168 (91%) Query: 62 NMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYC 121 NM++ALA+A C+RC+ F+PAE IVNSNGELYHE CFVCAQCF+ FPEGLFYEFEGRKYC Sbjct: 5 NMSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYC 64 Query: 122 EHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCR 181 EHDFQMLFAPCC CGEFIIGRVIKAMNN+WHP CFRC+LC LAD+GFVKNAGRHLCR Sbjct: 65 EHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCR 124 Query: 182 PCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQE 229 PCHNREKA+GLGKYICQ+CH +IDEQPL+F++D YHPDHFNC +CG+E Sbjct: 125 PCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKE 172 Score = 74.7 bits (182), Expect = 7e-14 Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 1/103 (0%) Query: 85 IVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRV 144 +VN+ G+ +H + FVCA+C + F YE +G YCE + LF C+ C I G V Sbjct: 209 VVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV 268 Query: 145 IKAMNNSWHPECFRCDLCQEVLA-DIGFVKNAGRHLCRPCHNR 186 + A+N +W CF C C L FV+ + +C+ C+ + Sbjct: 269 VSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 311 Score = 59.7 bits (143), Expect = 2e-09 Identities = 40/166 (24%), Positives = 62/166 (37%), Gaps = 8/166 (4%) Query: 64 ANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEH 123 A L C+RC E + + YH F C C ++ E +G YC Sbjct: 132 AKGLGKYICQRCH--LVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLP 188 Query: 124 DFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 183 + P C C I GRV+ A+ WH E F C C++ + G C Sbjct: 189 CHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETH 248 Query: 184 HNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQE 229 +N+ L +C C +I+ + N + F+C+ C + Sbjct: 249 YNQ-----LFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSK 289 Score = 34.3 bits (77), Expect = 0.10 Identities = 23/90 (25%), Positives = 36/90 (40%), Gaps = 5/90 (5%) Query: 143 RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHA 202 R++ + +H CF C C + F + GR C H+ + L C C Sbjct: 27 RIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE--HDFQM---LFAPCCGSCGE 81 Query: 203 IIDEQPLIFKNDPYHPDHFNCANCGQEGSD 232 I + + N+ +HP F C C E +D Sbjct: 82 FIIGRVIKAMNNNWHPGCFRCELCDVELAD 111 >gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2 [Homo sapiens] Length = 365 Score = 320 bits (819), Expect = 9e-88 Identities = 135/168 (80%), Positives = 153/168 (91%) Query: 62 NMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYC 121 NM++ALA+A C+RC+ F+PAE IVNSNGELYHE CFVCAQCF+ FPEGLFYEFEGRKYC Sbjct: 29 NMSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYC 88 Query: 122 EHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCR 181 EHDFQMLFAPCC CGEFIIGRVIKAMNN+WHP CFRC+LC LAD+GFVKNAGRHLCR Sbjct: 89 EHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCR 148 Query: 182 PCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQE 229 PCHNREKA+GLGKYICQ+CH +IDEQPL+F++D YHPDHFNC +CG+E Sbjct: 149 PCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKE 196 Score = 74.7 bits (182), Expect = 7e-14 Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 1/103 (0%) Query: 85 IVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRV 144 +VN+ G+ +H + FVCA+C + F YE +G YCE + LF C+ C I G V Sbjct: 233 VVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV 292 Query: 145 IKAMNNSWHPECFRCDLCQEVLA-DIGFVKNAGRHLCRPCHNR 186 + A+N +W CF C C L FV+ + +C+ C+ + Sbjct: 293 VSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 335 Score = 59.7 bits (143), Expect = 2e-09 Identities = 40/166 (24%), Positives = 62/166 (37%), Gaps = 8/166 (4%) Query: 64 ANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEH 123 A L C+RC E + + YH F C C ++ E +G YC Sbjct: 156 AKGLGKYICQRCH--LVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLP 212 Query: 124 DFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 183 + P C C I GRV+ A+ WH E F C C++ + G C Sbjct: 213 CHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETH 272 Query: 184 HNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQE 229 +N+ L +C C +I+ + N + F+C+ C + Sbjct: 273 YNQ-----LFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSK 313 Score = 34.3 bits (77), Expect = 0.10 Identities = 23/90 (25%), Positives = 36/90 (40%), Gaps = 5/90 (5%) Query: 143 RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHA 202 R++ + +H CF C C + F + GR C H+ + L C C Sbjct: 51 RIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE--HDFQM---LFAPCCGSCGE 105 Query: 203 IIDEQPLIFKNDPYHPDHFNCANCGQEGSD 232 I + + N+ +HP F C C E +D Sbjct: 106 FIIGRVIKAMNNNWHPGCFRCELCDVELAD 135 >gi|238776788 LIM and senescent cell antigen-like domains 2 isoform 5 [Homo sapiens] Length = 336 Score = 317 bits (813), Expect = 5e-87 Identities = 134/167 (80%), Positives = 152/167 (91%) Query: 63 MANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 122 M++ALA+A C+RC+ F+PAE IVNSNGELYHE CFVCAQCF+ FPEGLFYEFEGRKYCE Sbjct: 1 MSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 60 Query: 123 HDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP 182 HDFQMLFAPCC CGEFIIGRVIKAMNN+WHP CFRC+LC LAD+GFVKNAGRHLCRP Sbjct: 61 HDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 120 Query: 183 CHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQE 229 CHNREKA+GLGKYICQ+CH +IDEQPL+F++D YHPDHFNC +CG+E Sbjct: 121 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKE 167 Score = 74.7 bits (182), Expect = 7e-14 Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 1/103 (0%) Query: 85 IVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRV 144 +VN+ G+ +H + FVCA+C + F YE +G YCE + LF C+ C I G V Sbjct: 204 VVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV 263 Query: 145 IKAMNNSWHPECFRCDLCQEVLA-DIGFVKNAGRHLCRPCHNR 186 + A+N +W CF C C L FV+ + +C+ C+ + Sbjct: 264 VSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 306 Score = 59.7 bits (143), Expect = 2e-09 Identities = 40/166 (24%), Positives = 62/166 (37%), Gaps = 8/166 (4%) Query: 64 ANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEH 123 A L C+RC E + + YH F C C ++ E +G YC Sbjct: 127 AKGLGKYICQRCH--LVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLP 183 Query: 124 DFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 183 + P C C I GRV+ A+ WH E F C C++ + G C Sbjct: 184 CHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETH 243 Query: 184 HNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQE 229 +N+ L +C C +I+ + N + F+C+ C + Sbjct: 244 YNQ-----LFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSK 284 Score = 34.3 bits (77), Expect = 0.10 Identities = 23/90 (25%), Positives = 36/90 (40%), Gaps = 5/90 (5%) Query: 143 RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHA 202 R++ + +H CF C C + F + GR C H+ + L C C Sbjct: 22 RIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE--HDFQM---LFAPCCGSCGE 76 Query: 203 IIDEQPLIFKNDPYHPDHFNCANCGQEGSD 232 I + + N+ +HP F C C E +D Sbjct: 77 FIIGRVIKAMNNNWHPGCFRCELCDVELAD 106 >gi|15743548 LIM and senescent cell antigen-like domains 3 [Homo sapiens] Length = 117 Score = 241 bits (616), Expect = 3e-64 Identities = 114/114 (100%), Positives = 114/114 (100%) Query: 1 MAFSGRARPCIIPENEEIPRAALNTVHEANGTEDERAVSKLQRRHSDVKVYKEFCDFYAK 60 MAFSGRARPCIIPENEEIPRAALNTVHEANGTEDERAVSKLQRRHSDVKVYKEFCDFYAK Sbjct: 1 MAFSGRARPCIIPENEEIPRAALNTVHEANGTEDERAVSKLQRRHSDVKVYKEFCDFYAK 60 Query: 61 FNMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYE 114 FNMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYE Sbjct: 61 FNMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYE 114 >gi|239758027 PREDICTED: similar to LIM and senescent cell antigen-like domains 1 [Homo sapiens] Length = 116 Score = 208 bits (530), Expect = 3e-54 Identities = 91/91 (100%), Positives = 91/91 (100%) Query: 137 GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYI 196 GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYI Sbjct: 26 GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYI 85 Query: 197 CQKCHAIIDEQPLIFKNDPYHPDHFNCANCG 227 CQKCHAIIDEQPLIFKNDPYHPDHFNCANCG Sbjct: 86 CQKCHAIIDEQPLIFKNDPYHPDHFNCANCG 116 Score = 34.3 bits (77), Expect = 0.10 Identities = 20/83 (24%), Positives = 36/83 (43%), Gaps = 5/83 (6%) Query: 85 IVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE--HDFQM---LFAPCCHQCGEF 139 ++ + +H +CF C C + + F + GR C H+ + L C +C Sbjct: 33 VIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAI 92 Query: 140 IIGRVIKAMNNSWHPECFRCDLC 162 I + + N+ +HP+ F C C Sbjct: 93 IDEQPLIFKNDPYHPDHFNCANC 115 >gi|170932518 paxillin isoform 3 [Homo sapiens] Length = 424 Score = 94.4 bits (233), Expect = 8e-20 Identities = 55/161 (34%), Positives = 76/161 (47%), Gaps = 9/161 (5%) Query: 67 LASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQF-PEGLFYEFEGRKYCEHDF 125 L S C C G + +V + +H + F CAQC F PEG F+E +G+ YC D+ Sbjct: 245 LFSPRCYYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEG-FHEKDGKAYCRKDY 301 Query: 126 QMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHN 185 +FAP C C I+ I A+N WHPECF C C + F ++ G+ C H Sbjct: 302 FDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE-VHY 360 Query: 186 REKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 226 E+ L C C I + + +HP+HF CA C Sbjct: 361 HERRGSL----CSGCQKPITGRCITAMAKKFHPEHFVCAFC 397 Score = 92.4 bits (228), Expect = 3e-19 Identities = 50/160 (31%), Positives = 76/160 (47%), Gaps = 7/160 (4%) Query: 67 LASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 126 +A C CK A +V + G+ +H + FVC C ++ F+E +G+ YCE D+ Sbjct: 186 VAKGVCGACKKPIAGQ--VVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYH 243 Query: 127 MLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNR 186 LF+P C+ C I+ +V+ A++ +WHPE F C C GF + G+ CR + Sbjct: 244 NLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFD 303 Query: 187 EKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 226 A C C I E + N +HP+ F C C Sbjct: 304 MFAPK-----CGGCARAILENYISALNTLWHPECFVCREC 338 Score = 75.9 bits (185), Expect = 3e-14 Identities = 39/109 (35%), Positives = 55/109 (50%), Gaps = 2/109 (1%) Query: 77 GGFAPA--ETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCH 134 GG A A E +++ L+H +CFVC +CF F G F+E +G+ YCE + C Sbjct: 310 GGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCS 369 Query: 135 QCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 183 C + I GR I AM +HPE F C C + L F + + C+ C Sbjct: 370 GCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNC 418 Score = 63.9 bits (154), Expect = 1e-10 Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 7/96 (7%) Query: 133 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLC-RPCHNREKARG 191 C C + I G+V+ AM +WHPE F C CQE + F + G+ C + HN R Sbjct: 191 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR- 249 Query: 192 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCG 227 C C+ I ++ + + +HP+HF CA CG Sbjct: 250 -----CYYCNGPILDKVVTALDRTWHPEHFFCAQCG 280 Score = 37.0 bits (84), Expect = 0.016 Identities = 15/44 (34%), Positives = 25/44 (56%) Query: 86 VNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLF 129 + + + +H + FVCA C +Q +G F E + YC++ F LF Sbjct: 380 ITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423 Score = 30.8 bits (68), Expect = 1.1 Identities = 12/38 (31%), Positives = 19/38 (50%) Query: 192 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQE 229 + K +C C I Q + +HP+HF C +C +E Sbjct: 186 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEE 223 >gi|170932516 paxillin isoform 2 [Homo sapiens] Length = 557 Score = 94.4 bits (233), Expect = 8e-20 Identities = 55/161 (34%), Positives = 76/161 (47%), Gaps = 9/161 (5%) Query: 67 LASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQF-PEGLFYEFEGRKYCEHDF 125 L S C C G + +V + +H + F CAQC F PEG F+E +G+ YC D+ Sbjct: 378 LFSPRCYYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEG-FHEKDGKAYCRKDY 434 Query: 126 QMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHN 185 +FAP C C I+ I A+N WHPECF C C + F ++ G+ C H Sbjct: 435 FDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE-VHY 493 Query: 186 REKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 226 E+ L C C I + + +HP+HF CA C Sbjct: 494 HERRGSL----CSGCQKPITGRCITAMAKKFHPEHFVCAFC 530 Score = 92.4 bits (228), Expect = 3e-19 Identities = 50/160 (31%), Positives = 76/160 (47%), Gaps = 7/160 (4%) Query: 67 LASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 126 +A C CK A +V + G+ +H + FVC C ++ F+E +G+ YCE D+ Sbjct: 319 VAKGVCGACKKPIAGQ--VVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYH 376 Query: 127 MLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNR 186 LF+P C+ C I+ +V+ A++ +WHPE F C C GF + G+ CR + Sbjct: 377 NLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFD 436 Query: 187 EKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 226 A C C I E + N +HP+ F C C Sbjct: 437 MFAPK-----CGGCARAILENYISALNTLWHPECFVCREC 471 Score = 75.9 bits (185), Expect = 3e-14 Identities = 39/109 (35%), Positives = 55/109 (50%), Gaps = 2/109 (1%) Query: 77 GGFAPA--ETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCH 134 GG A A E +++ L+H +CFVC +CF F G F+E +G+ YCE + C Sbjct: 443 GGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCS 502 Query: 135 QCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 183 C + I GR I AM +HPE F C C + L F + + C+ C Sbjct: 503 GCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNC 551 Score = 63.9 bits (154), Expect = 1e-10 Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 7/96 (7%) Query: 133 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLC-RPCHNREKARG 191 C C + I G+V+ AM +WHPE F C CQE + F + G+ C + HN R Sbjct: 324 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR- 382 Query: 192 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCG 227 C C+ I ++ + + +HP+HF CA CG Sbjct: 383 -----CYYCNGPILDKVVTALDRTWHPEHFFCAQCG 413 Score = 37.0 bits (84), Expect = 0.016 Identities = 15/44 (34%), Positives = 25/44 (56%) Query: 86 VNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLF 129 + + + +H + FVCA C +Q +G F E + YC++ F LF Sbjct: 513 ITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556 Score = 30.8 bits (68), Expect = 1.1 Identities = 12/38 (31%), Positives = 19/38 (50%) Query: 192 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQE 229 + K +C C I Q + +HP+HF C +C +E Sbjct: 319 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEE 356 >gi|170932514 paxillin isoform 1 [Homo sapiens] Length = 591 Score = 94.4 bits (233), Expect = 8e-20 Identities = 55/161 (34%), Positives = 76/161 (47%), Gaps = 9/161 (5%) Query: 67 LASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQF-PEGLFYEFEGRKYCEHDF 125 L S C C G + +V + +H + F CAQC F PEG F+E +G+ YC D+ Sbjct: 412 LFSPRCYYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEG-FHEKDGKAYCRKDY 468 Query: 126 QMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHN 185 +FAP C C I+ I A+N WHPECF C C + F ++ G+ C H Sbjct: 469 FDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE-VHY 527 Query: 186 REKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 226 E+ L C C I + + +HP+HF CA C Sbjct: 528 HERRGSL----CSGCQKPITGRCITAMAKKFHPEHFVCAFC 564 Score = 92.4 bits (228), Expect = 3e-19 Identities = 50/160 (31%), Positives = 76/160 (47%), Gaps = 7/160 (4%) Query: 67 LASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 126 +A C CK A +V + G+ +H + FVC C ++ F+E +G+ YCE D+ Sbjct: 353 VAKGVCGACKKPIAGQ--VVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYH 410 Query: 127 MLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNR 186 LF+P C+ C I+ +V+ A++ +WHPE F C C GF + G+ CR + Sbjct: 411 NLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFD 470 Query: 187 EKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 226 A C C I E + N +HP+ F C C Sbjct: 471 MFAPK-----CGGCARAILENYISALNTLWHPECFVCREC 505 Score = 75.9 bits (185), Expect = 3e-14 Identities = 39/109 (35%), Positives = 55/109 (50%), Gaps = 2/109 (1%) Query: 77 GGFAPA--ETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCH 134 GG A A E +++ L+H +CFVC +CF F G F+E +G+ YCE + C Sbjct: 477 GGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCS 536 Query: 135 QCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 183 C + I GR I AM +HPE F C C + L F + + C+ C Sbjct: 537 GCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNC 585 Score = 63.9 bits (154), Expect = 1e-10 Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 7/96 (7%) Query: 133 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLC-RPCHNREKARG 191 C C + I G+V+ AM +WHPE F C CQE + F + G+ C + HN R Sbjct: 358 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR- 416 Query: 192 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCG 227 C C+ I ++ + + +HP+HF CA CG Sbjct: 417 -----CYYCNGPILDKVVTALDRTWHPEHFFCAQCG 447 Score = 37.0 bits (84), Expect = 0.016 Identities = 15/44 (34%), Positives = 25/44 (56%) Query: 86 VNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLF 129 + + + +H + FVCA C +Q +G F E + YC++ F LF Sbjct: 547 ITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590 Score = 30.8 bits (68), Expect = 1.1 Identities = 12/38 (31%), Positives = 19/38 (50%) Query: 192 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQE 229 + K +C C I Q + +HP+HF C +C +E Sbjct: 353 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEE 390 >gi|109638745 transforming growth factor beta 1 induced transcript 1 isoform 1 [Homo sapiens] Length = 461 Score = 91.7 bits (226), Expect = 5e-19 Identities = 48/142 (33%), Positives = 69/142 (48%), Gaps = 5/142 (3%) Query: 85 IVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRV 144 +V + G +H + F C C + F + F+E EGR YC DF LFAP C C I+ Sbjct: 298 MVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNY 357 Query: 145 IKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII 204 I A++ WHP+CF C C + F ++ GR LC ++ RG +C C + Sbjct: 358 ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCE--NHFHARRG---SLCATCGLPV 412 Query: 205 DEQPLIFKNDPYHPDHFNCANC 226 + + +HPDHF C C Sbjct: 413 TGRCVSALGRRFHPDHFTCTFC 434 Score = 89.0 bits (219), Expect = 4e-18 Identities = 40/117 (34%), Positives = 59/117 (50%), Gaps = 2/117 (1%) Query: 67 LASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 126 L + C+ C+G + +++ L+H CFVC +CF F G F+E EGR CE+ F Sbjct: 341 LFAPRCQGCQGPIL--DNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFH 398 Query: 127 MLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 183 C CG + GR + A+ +HP+ F C C L F + AG+ C+PC Sbjct: 399 ARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 455 Score = 76.6 bits (187), Expect = 2e-14 Identities = 47/159 (29%), Positives = 66/159 (41%), Gaps = 7/159 (4%) Query: 68 ASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQM 127 A C C A +V + G +H + FVC C F+E +G +C + Sbjct: 224 AKGLCGSCNKPIAGQ--VVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFE 281 Query: 128 LFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE 187 F+P C C + I +++ A+ WHPE F C C E D GF + GR C R Sbjct: 282 RFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYC-----RR 336 Query: 188 KARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 226 L CQ C I + + + +HPD F C C Sbjct: 337 DFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCREC 375 Score = 60.1 bits (144), Expect = 2e-09 Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 7/101 (6%) Query: 133 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCH-NREKARG 191 C C + I G+V+ A+ +WHPE F C C L F + G C C+ R R Sbjct: 228 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR- 286 Query: 192 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQEGSD 232 C C+ I + + +HP+HF C +CG+ D Sbjct: 287 -----CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGD 322 Score = 37.0 bits (84), Expect = 0.016 Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 2/68 (2%) Query: 62 NMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYC 121 N +A + C C G V++ G +H F C C + +G F E G+ YC Sbjct: 395 NHFHARRGSLCATC--GLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYC 452 Query: 122 EHDFQMLF 129 + F LF Sbjct: 453 QPCFLKLF 460 >gi|21361591 transforming growth factor beta 1 induced transcript 1 isoform 2 [Homo sapiens] Length = 444 Score = 91.7 bits (226), Expect = 5e-19 Identities = 48/142 (33%), Positives = 69/142 (48%), Gaps = 5/142 (3%) Query: 85 IVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRV 144 +V + G +H + F C C + F + F+E EGR YC DF LFAP C C I+ Sbjct: 281 MVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNY 340 Query: 145 IKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII 204 I A++ WHP+CF C C + F ++ GR LC ++ RG +C C + Sbjct: 341 ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCE--NHFHARRG---SLCATCGLPV 395 Query: 205 DEQPLIFKNDPYHPDHFNCANC 226 + + +HPDHF C C Sbjct: 396 TGRCVSALGRRFHPDHFTCTFC 417 Score = 89.0 bits (219), Expect = 4e-18 Identities = 40/117 (34%), Positives = 59/117 (50%), Gaps = 2/117 (1%) Query: 67 LASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 126 L + C+ C+G + +++ L+H CFVC +CF F G F+E EGR CE+ F Sbjct: 324 LFAPRCQGCQGPIL--DNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFH 381 Query: 127 MLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 183 C CG + GR + A+ +HP+ F C C L F + AG+ C+PC Sbjct: 382 ARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 438 Score = 76.6 bits (187), Expect = 2e-14 Identities = 47/159 (29%), Positives = 66/159 (41%), Gaps = 7/159 (4%) Query: 68 ASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQM 127 A C C A +V + G +H + FVC C F+E +G +C + Sbjct: 207 AKGLCGSCNKPIAGQ--VVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFE 264 Query: 128 LFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE 187 F+P C C + I +++ A+ WHPE F C C E D GF + GR C R Sbjct: 265 RFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYC-----RR 319 Query: 188 KARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 226 L CQ C I + + + +HPD F C C Sbjct: 320 DFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCREC 358 Score = 60.1 bits (144), Expect = 2e-09 Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 7/101 (6%) Query: 133 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCH-NREKARG 191 C C + I G+V+ A+ +WHPE F C C L F + G C C+ R R Sbjct: 211 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR- 269 Query: 192 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQEGSD 232 C C+ I + + +HP+HF C +CG+ D Sbjct: 270 -----CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGD 305 Score = 37.0 bits (84), Expect = 0.016 Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 2/68 (2%) Query: 62 NMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYC 121 N +A + C C G V++ G +H F C C + +G F E G+ YC Sbjct: 378 NHFHARRGSLCATC--GLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYC 435 Query: 122 EHDFQMLF 129 + F LF Sbjct: 436 QPCFLKLF 443 >gi|58530845 zyxin [Homo sapiens] Length = 572 Score = 91.3 bits (225), Expect = 7e-19 Identities = 53/172 (30%), Positives = 78/172 (45%), Gaps = 14/172 (8%) Query: 65 NALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHD 124 N + C RC A A+ V + G+L+H CF C QC QQ FY EG YCE Sbjct: 377 NVAVNELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGC 436 Query: 125 FQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGF-VKNAGRHLCRPC 183 + C+ CGE I R+++A ++HP CF C +C L F V A R C P Sbjct: 437 YTDTLEK-CNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPD 495 Query: 184 HNREKARGLGKYICQKCHAIIDEQP-------LIFKNDPYHPDHFNCANCGQ 228 ++++ A C C I +P ++ + +H + C +CG+ Sbjct: 496 YHKQYAPR-----CSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGK 542 Score = 59.3 bits (142), Expect = 3e-09 Identities = 37/127 (29%), Positives = 60/127 (47%), Gaps = 13/127 (10%) Query: 71 TCERCKGGFAP-AETIVNSNGELYHEQCFVCAQCFQQFPEGLFY-EFEGRKYCEHDFQML 128 T E+C P + ++ + G+ YH CF C C + F + R +C D+ Sbjct: 440 TLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQ 499 Query: 129 FAPCCHQCGEFII---GRV----IKAMNNSWHPECFRCDLCQEVLA----DIGFVKNAGR 177 +AP C C E I+ GR + A++ ++H +C++C+ C + L+ D G G Sbjct: 500 YAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGH 559 Query: 178 HLCRPCH 184 LCR CH Sbjct: 560 VLCRKCH 566 >gi|4508047 zyxin [Homo sapiens] Length = 572 Score = 91.3 bits (225), Expect = 7e-19 Identities = 53/172 (30%), Positives = 78/172 (45%), Gaps = 14/172 (8%) Query: 65 NALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHD 124 N + C RC A A+ V + G+L+H CF C QC QQ FY EG YCE Sbjct: 377 NVAVNELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGC 436 Query: 125 FQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGF-VKNAGRHLCRPC 183 + C+ CGE I R+++A ++HP CF C +C L F V A R C P Sbjct: 437 YTDTLEK-CNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPD 495 Query: 184 HNREKARGLGKYICQKCHAIIDEQP-------LIFKNDPYHPDHFNCANCGQ 228 ++++ A C C I +P ++ + +H + C +CG+ Sbjct: 496 YHKQYAPR-----CSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGK 542 Score = 59.3 bits (142), Expect = 3e-09 Identities = 37/127 (29%), Positives = 60/127 (47%), Gaps = 13/127 (10%) Query: 71 TCERCKGGFAP-AETIVNSNGELYHEQCFVCAQCFQQFPEGLFY-EFEGRKYCEHDFQML 128 T E+C P + ++ + G+ YH CF C C + F + R +C D+ Sbjct: 440 TLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQ 499 Query: 129 FAPCCHQCGEFII---GRV----IKAMNNSWHPECFRCDLCQEVLA----DIGFVKNAGR 177 +AP C C E I+ GR + A++ ++H +C++C+ C + L+ D G G Sbjct: 500 YAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGH 559 Query: 178 HLCRPCH 184 LCR CH Sbjct: 560 VLCRKCH 566 >gi|221316659 leupaxin isoform 1 [Homo sapiens] Length = 391 Score = 90.5 bits (223), Expect = 1e-18 Identities = 45/145 (31%), Positives = 72/145 (49%), Gaps = 5/145 (3%) Query: 82 AETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFII 141 A ++++ G+ +H + FVC C ++ F+E G YC +D+ LF+P C C I+ Sbjct: 165 AGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPIL 224 Query: 142 GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCH 201 +V+ AMN +WHPE F C C EV GF + + C R+ + C C+ Sbjct: 225 DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC-----RKDFLAMFSPKCGGCN 279 Query: 202 AIIDEQPLIFKNDPYHPDHFNCANC 226 + E L + +HP+ F C +C Sbjct: 280 RPVLENYLSAMDTVWHPECFVCGDC 304 Score = 87.8 bits (216), Expect = 8e-18 Identities = 47/138 (34%), Positives = 67/138 (48%), Gaps = 13/138 (9%) Query: 52 KEFC--DFYAKFNMANALASATCERCKGGFAPA-ETIVNSNGELYHEQCFVCAQCFQQFP 108 K +C DF A F+ +C G P E +++ ++H +CFVC CF F Sbjct: 260 KPYCRKDFLAMFS----------PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFS 309 Query: 109 EGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLAD 168 G F+E +GR +CE + CH CG+ I GR I AM +HPE F C C L+ Sbjct: 310 TGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSK 369 Query: 169 IGFVKNAGRHLCRPCHNR 186 F + + C+PC N+ Sbjct: 370 GIFREQNDKTYCQPCFNK 387 Score = 83.6 bits (205), Expect = 1e-16 Identities = 43/154 (27%), Positives = 71/154 (46%), Gaps = 6/154 (3%) Query: 74 RCKGGFAPA-ETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPC 132 RC AP + ++ + + +H + F C+ C + F F+E + + YC DF +F+P Sbjct: 215 RCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPK 274 Query: 133 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGL 192 C C ++ + AM+ WHPECF C C + F + GR C ++ + Sbjct: 275 CGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT-- 332 Query: 193 GKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 226 +C C I + + +HP+HF CA C Sbjct: 333 ---LCHGCGQPITGRCISAMGYKFHPEHFVCAFC 363 Score = 65.1 bits (157), Expect = 5e-11 Identities = 33/96 (34%), Positives = 50/96 (52%), Gaps = 5/96 (5%) Query: 133 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGL 192 C C + I G+VI A+ SWHPE F C C+E + F + +G C +++ L Sbjct: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQ-----L 211 Query: 193 GKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQ 228 C C A I ++ L N +HP+HF C++CG+ Sbjct: 212 FSPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGE 247 Score = 38.9 bits (89), Expect = 0.004 Identities = 16/44 (36%), Positives = 25/44 (56%) Query: 86 VNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLF 129 +++ G +H + FVCA C Q +G+F E + YC+ F LF Sbjct: 346 ISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389 Score = 27.7 bits (60), Expect = 9.7 Identities = 10/33 (30%), Positives = 16/33 (48%) Query: 197 CQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQE 229 C C I + + +HP+HF C +C +E Sbjct: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEE 189 >gi|4758670 leupaxin isoform 2 [Homo sapiens] Length = 386 Score = 90.5 bits (223), Expect = 1e-18 Identities = 45/145 (31%), Positives = 72/145 (49%), Gaps = 5/145 (3%) Query: 82 AETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFII 141 A ++++ G+ +H + FVC C ++ F+E G YC +D+ LF+P C C I+ Sbjct: 160 AGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPIL 219 Query: 142 GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCH 201 +V+ AMN +WHPE F C C EV GF + + C R+ + C C+ Sbjct: 220 DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC-----RKDFLAMFSPKCGGCN 274 Query: 202 AIIDEQPLIFKNDPYHPDHFNCANC 226 + E L + +HP+ F C +C Sbjct: 275 RPVLENYLSAMDTVWHPECFVCGDC 299 Score = 87.8 bits (216), Expect = 8e-18 Identities = 47/138 (34%), Positives = 67/138 (48%), Gaps = 13/138 (9%) Query: 52 KEFC--DFYAKFNMANALASATCERCKGGFAPA-ETIVNSNGELYHEQCFVCAQCFQQFP 108 K +C DF A F+ +C G P E +++ ++H +CFVC CF F Sbjct: 255 KPYCRKDFLAMFS----------PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFS 304 Query: 109 EGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLAD 168 G F+E +GR +CE + CH CG+ I GR I AM +HPE F C C L+ Sbjct: 305 TGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSK 364 Query: 169 IGFVKNAGRHLCRPCHNR 186 F + + C+PC N+ Sbjct: 365 GIFREQNDKTYCQPCFNK 382 Score = 83.6 bits (205), Expect = 1e-16 Identities = 43/154 (27%), Positives = 71/154 (46%), Gaps = 6/154 (3%) Query: 74 RCKGGFAPA-ETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPC 132 RC AP + ++ + + +H + F C+ C + F F+E + + YC DF +F+P Sbjct: 210 RCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPK 269 Query: 133 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGL 192 C C ++ + AM+ WHPECF C C + F + GR C ++ + Sbjct: 270 CGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT-- 327 Query: 193 GKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 226 +C C I + + +HP+HF CA C Sbjct: 328 ---LCHGCGQPITGRCISAMGYKFHPEHFVCAFC 358 Score = 65.1 bits (157), Expect = 5e-11 Identities = 33/96 (34%), Positives = 50/96 (52%), Gaps = 5/96 (5%) Query: 133 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGL 192 C C + I G+VI A+ SWHPE F C C+E + F + +G C +++ L Sbjct: 152 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQ-----L 206 Query: 193 GKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQ 228 C C A I ++ L N +HP+HF C++CG+ Sbjct: 207 FSPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGE 242 Score = 38.9 bits (89), Expect = 0.004 Identities = 16/44 (36%), Positives = 25/44 (56%) Query: 86 VNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLF 129 +++ G +H + FVCA C Q +G+F E + YC+ F LF Sbjct: 341 ISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384 Score = 27.7 bits (60), Expect = 9.7 Identities = 10/33 (30%), Positives = 16/33 (48%) Query: 197 CQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQE 229 C C I + + +HP+HF C +C +E Sbjct: 152 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEE 184 >gi|7657307 LIM domains containing 1 [Homo sapiens] Length = 676 Score = 89.0 bits (219), Expect = 4e-18 Identities = 54/176 (30%), Positives = 78/176 (44%), Gaps = 23/176 (13%) Query: 72 CERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ----M 127 C +C G A + G LYH+ CF CA C ++ FY G+ +CE DF Sbjct: 472 CVKCSKGVFGAGQACQAMGNLYHDTCFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQ 531 Query: 128 LFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGF-VKNAGRHLCRPCHNR 186 A C CG I+ +++A+ S+HP CFRC +C E L + F V + + C Sbjct: 532 QSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYC------ 585 Query: 187 EKARGLGKYICQKCHAI---------IDEQPLIFKND-PYHPDHFNCANCGQEGSD 232 R K + KC A DE + D YH + ++C +CG E +D Sbjct: 586 --VRDYHKVLAPKCAACGLPILPPEGSDETIRVVSMDRDYHVECYHCEDCGLELND 639 >gi|14249622 ajuba isoform 1 [Homo sapiens] Length = 538 Score = 85.9 bits (211), Expect = 3e-17 Identities = 56/179 (31%), Positives = 82/179 (45%), Gaps = 18/179 (10%) Query: 71 TCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHD-----F 125 TC +C G + LYH QCFVC C + FY G YCE D F Sbjct: 337 TCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGF 396 Query: 126 QMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGF-VKNAGRHLCRPCH 184 Q CC CG I+ ++++AM S+HP CFRC +C + L I F V + + C + Sbjct: 397 QEAAEKCC-VCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDY 455 Query: 185 NRE---KARGLGKYI--CQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQEGSD---CRC 235 ++ K G+ I + C I+ +I + YH + ++C +C + SD C C Sbjct: 456 HKNYAPKCAACGQPILPSEGCEDIV---RVISMDRDYHFECYHCEDCRMQLSDEEGCCC 511 >gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens] Length = 746 Score = 80.1 bits (196), Expect = 2e-15 Identities = 46/161 (28%), Positives = 70/161 (43%), Gaps = 11/161 (6%) Query: 73 ERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPC 132 E CKG +T + +H +CF C C +G F+ G C D+Q ++ Sbjct: 44 EPCKGEVLRVQT------KHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTR 97 Query: 133 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRH-LCRPCHNREKARG 191 CH CGEF+ G V+ A+ ++HP CF C +C+ V GR LC+ C + Sbjct: 98 CHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSP 157 Query: 192 LGKYICQKC----HAIIDEQPLIFKNDPYHPDHFNCANCGQ 228 C I + Q L+ + +H F C +CG+ Sbjct: 158 KETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGK 198 Score = 75.1 bits (183), Expect = 5e-14 Identities = 53/180 (29%), Positives = 76/180 (42%), Gaps = 21/180 (11%) Query: 72 CERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGR----KYCEHDF-- 125 C C G F E +V + G+ YH CF C C + FP G F GR + C Sbjct: 98 CHGC-GEFVEGE-VVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSS 155 Query: 126 ---QMLFAPCCHQCGEFII-GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCR 181 + F+ C CG I G+ + A++ WH CF+C C +VL ++ G C Sbjct: 156 SPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTG-EYISKDGAPYCE 214 Query: 182 PCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQ---EGSDCRCTGA 238 + +GL C+ CH I + L + YHP C+ C Q EG + G+ Sbjct: 215 KDY-----QGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGS 269 Score = 64.7 bits (156), Expect = 7e-11 Identities = 30/100 (30%), Positives = 50/100 (50%), Gaps = 2/100 (2%) Query: 69 SATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 128 S+ C C + ++ + + +H CF C C + G + +G YCE D+Q L Sbjct: 163 SSNCAGCGRDIKNGQALLALDKQ-WHLGCFKCKSCGKVLT-GEYISKDGAPYCEKDYQGL 220 Query: 129 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLAD 168 F C C +FI G+V++A + +HP C RC C ++ + Sbjct: 221 FGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTE 260 Score = 56.6 bits (135), Expect = 2e-08 Identities = 32/113 (28%), Positives = 46/113 (40%), Gaps = 15/113 (13%) Query: 133 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGL 192 CH+CGE G V++ +H +CF C +C LA GF G +LC + R Sbjct: 39 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTR- 97 Query: 193 GKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQ----------EGSDCRC 235 C C ++ + + YHP+ F C C + G DC C Sbjct: 98 ----CHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLC 146 >gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens] Length = 718 Score = 80.1 bits (196), Expect = 2e-15 Identities = 46/161 (28%), Positives = 70/161 (43%), Gaps = 11/161 (6%) Query: 73 ERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPC 132 E CKG +T + +H +CF C C +G F+ G C D+Q ++ Sbjct: 44 EPCKGEVLRVQT------KHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTR 97 Query: 133 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRH-LCRPCHNREKARG 191 CH CGEF+ G V+ A+ ++HP CF C +C+ V GR LC+ C + Sbjct: 98 CHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSP 157 Query: 192 LGKYICQKC----HAIIDEQPLIFKNDPYHPDHFNCANCGQ 228 C I + Q L+ + +H F C +CG+ Sbjct: 158 KETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGK 198 Score = 75.1 bits (183), Expect = 5e-14 Identities = 53/180 (29%), Positives = 76/180 (42%), Gaps = 21/180 (11%) Query: 72 CERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGR----KYCEHDF-- 125 C C G F E +V + G+ YH CF C C + FP G F GR + C Sbjct: 98 CHGC-GEFVEGE-VVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSS 155 Query: 126 ---QMLFAPCCHQCGEFII-GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCR 181 + F+ C CG I G+ + A++ WH CF+C C +VL ++ G C Sbjct: 156 SPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTG-EYISKDGAPYCE 214 Query: 182 PCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQ---EGSDCRCTGA 238 + +GL C+ CH I + L + YHP C+ C Q EG + G+ Sbjct: 215 KDY-----QGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGS 269 Score = 64.7 bits (156), Expect = 7e-11 Identities = 30/100 (30%), Positives = 50/100 (50%), Gaps = 2/100 (2%) Query: 69 SATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 128 S+ C C + ++ + + +H CF C C + G + +G YCE D+Q L Sbjct: 163 SSNCAGCGRDIKNGQALLALDKQ-WHLGCFKCKSCGKVLT-GEYISKDGAPYCEKDYQGL 220 Query: 129 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLAD 168 F C C +FI G+V++A + +HP C RC C ++ + Sbjct: 221 FGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTE 260 Score = 56.6 bits (135), Expect = 2e-08 Identities = 32/113 (28%), Positives = 46/113 (40%), Gaps = 15/113 (13%) Query: 133 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGL 192 CH+CGE G V++ +H +CF C +C LA GF G +LC + R Sbjct: 39 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTR- 97 Query: 193 GKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQ----------EGSDCRC 235 C C ++ + + YHP+ F C C + G DC C Sbjct: 98 ----CHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLC 146 >gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens] Length = 778 Score = 80.1 bits (196), Expect = 2e-15 Identities = 46/161 (28%), Positives = 70/161 (43%), Gaps = 11/161 (6%) Query: 73 ERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPC 132 E CKG +T + +H +CF C C +G F+ G C D+Q ++ Sbjct: 104 EPCKGEVLRVQT------KHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTR 157 Query: 133 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRH-LCRPCHNREKARG 191 CH CGEF+ G V+ A+ ++HP CF C +C+ V GR LC+ C + Sbjct: 158 CHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSP 217 Query: 192 LGKYICQKC----HAIIDEQPLIFKNDPYHPDHFNCANCGQ 228 C I + Q L+ + +H F C +CG+ Sbjct: 218 KETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGK 258 Score = 75.1 bits (183), Expect = 5e-14 Identities = 53/180 (29%), Positives = 76/180 (42%), Gaps = 21/180 (11%) Query: 72 CERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGR----KYCEHDF-- 125 C C G F E +V + G+ YH CF C C + FP G F GR + C Sbjct: 158 CHGC-GEFVEGE-VVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSS 215 Query: 126 ---QMLFAPCCHQCGEFII-GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCR 181 + F+ C CG I G+ + A++ WH CF+C C +VL ++ G C Sbjct: 216 SPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTG-EYISKDGAPYCE 274 Query: 182 PCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQ---EGSDCRCTGA 238 + +GL C+ CH I + L + YHP C+ C Q EG + G+ Sbjct: 275 KDY-----QGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGS 329 Score = 64.7 bits (156), Expect = 7e-11 Identities = 30/100 (30%), Positives = 50/100 (50%), Gaps = 2/100 (2%) Query: 69 SATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 128 S+ C C + ++ + + +H CF C C + G + +G YCE D+Q L Sbjct: 223 SSNCAGCGRDIKNGQALLALDKQ-WHLGCFKCKSCGKVLT-GEYISKDGAPYCEKDYQGL 280 Query: 129 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLAD 168 F C C +FI G+V++A + +HP C RC C ++ + Sbjct: 281 FGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTE 320 Score = 56.6 bits (135), Expect = 2e-08 Identities = 32/113 (28%), Positives = 46/113 (40%), Gaps = 15/113 (13%) Query: 133 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGL 192 CH+CGE G V++ +H +CF C +C LA GF G +LC + R Sbjct: 99 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTR- 157 Query: 193 GKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQ----------EGSDCRC 235 C C ++ + + YHP+ F C C + G DC C Sbjct: 158 ----CHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLC 206 >gi|30410801 activator of cAMP-responsive element modulator (CREM) in testis [Homo sapiens] Length = 284 Score = 79.7 bits (195), Expect = 2e-15 Identities = 45/159 (28%), Positives = 64/159 (40%), Gaps = 3/159 (1%) Query: 69 SATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 128 S+ C CK P + G +HE CFVC C Q E YC F+ Sbjct: 99 SSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKE 158 Query: 129 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 188 FA C+ C + I I + WH ECF C C++ L + F+ C C+N Sbjct: 159 FAHYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLY 218 Query: 189 ARGLGKYICQK-CHAIIDEQPLIFKNDPYHPDHFNCANC 226 A C K + + + F++ +H + FNC C Sbjct: 219 ANKC--VACSKPISGLTGAKFICFQDSQWHSECFNCGKC 255 Score = 67.8 bits (164), Expect = 8e-12 Identities = 38/160 (23%), Positives = 63/160 (39%), Gaps = 7/160 (4%) Query: 72 CERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAP 131 CE CK + +HE CF C +C E F + R C + + Sbjct: 41 CEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSS 100 Query: 132 CCHQCGEFII--GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKA 189 C C I+ R ++ N WH CF C+ C++ + + + C PC +E A Sbjct: 101 KCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFA 160 Query: 190 RGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQE 229 + C C +I + F + +H + F C+ C ++ Sbjct: 161 -----HYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKD 195 Score = 58.5 bits (140), Expect = 5e-09 Identities = 33/121 (27%), Positives = 52/121 (42%), Gaps = 16/121 (13%) Query: 72 CERCKGGFAPAETIVNSNG-----ELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 126 C CK ++ S G +L+H++CF+C+ C + E F + +C + Sbjct: 163 CNFCK-------KVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYN 215 Query: 127 MLFAPCCHQCGEFIIG----RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP 182 L+A C C + I G + I ++ WH ECF C C L GF+ C+ Sbjct: 216 HLYANKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQK 275 Query: 183 C 183 C Sbjct: 276 C 276 Score = 49.7 bits (117), Expect = 2e-06 Identities = 33/135 (24%), Positives = 52/135 (38%), Gaps = 9/135 (6%) Query: 98 FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIG--RVIKAMNNSWHPE 155 F C C + + YC + +F+ C +C + I + + + WH Sbjct: 6 FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65 Query: 156 CFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFKN 213 CF+C C L + F R LC C++ E + C C I + + FK Sbjct: 66 CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSK-----CFHCKRTIMPGSRKMEFKG 120 Query: 214 DPYHPDHFNCANCGQ 228 + +H F C NC Q Sbjct: 121 NYWHETCFVCENCRQ 135 >gi|122937269 Wilms tumor 1 interacting protein [Homo sapiens] Length = 430 Score = 79.7 bits (195), Expect = 2e-15 Identities = 50/177 (28%), Positives = 76/177 (42%), Gaps = 18/177 (10%) Query: 72 CERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ----M 127 C +C G A+ + G LYH CF C C ++ FY + YC+ DF Sbjct: 225 CIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQ 284 Query: 128 LFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHL--CRPCHN 185 A C CG I+ +++A+ S+HP CFRC +C E L + F + ++ R H Sbjct: 285 QTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHT 344 Query: 186 --REKARGLGKYI--CQKCHAIIDEQPLIFKNDPYHPDHFNCANC-----GQEGSDC 233 K + I Q C I ++ + YH ++C +C G+EG C Sbjct: 345 VFAPKCASCARPILPAQGCETTI---RVVSMDRDYHVACYHCEDCGLQLSGEEGRRC 398 Score = 55.5 bits (132), Expect = 4e-08 Identities = 41/136 (30%), Positives = 60/136 (44%), Gaps = 18/136 (13%) Query: 71 TCERCKG-GFAPAETIVNSNGELYHEQCF---VCAQCFQQFPEGLFYEFEGRKYCEHDFQ 126 T ++C G E I+ + G+ YH CF VC +C P + E YC D+ Sbjct: 286 TADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVP--FTVDVENNIYCVRDYH 343 Query: 127 MLFAPCCHQCGEFIIG--------RVIKAMNNSWHPECFRCDLCQ-EVLADIG--FVKNA 175 +FAP C C I+ RV+ +M+ +H C+ C+ C ++ + G A Sbjct: 344 TVFAPKCASCARPILPAQGCETTIRVV-SMDRDYHVACYHCEDCGLQLSGEEGRRCYPLA 402 Query: 176 GRHLCRPCHNREKARG 191 G LCR CH R G Sbjct: 403 GHLLCRRCHLRRLQPG 418 >gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] Length = 280 Score = 78.6 bits (192), Expect = 5e-15 Identities = 45/197 (22%), Positives = 77/197 (39%), Gaps = 20/197 (10%) Query: 45 HSDVKVYKEFCDFYAKFNMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCF 104 H +K + +FC + TC C+ V+ +H+ CF CA+C Sbjct: 26 HCCLKCFDKFC-------------ANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCL 72 Query: 105 QQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIG--RVIKAMNNSWHPECFRCDLC 162 F + + C +P C C + I+ + ++ WH +CF C C Sbjct: 73 HPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNC 132 Query: 163 QEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFN 222 ++V+ F C CH + A+ C KC+ I + +++ P+H D F Sbjct: 133 KQVIGTGSFFPKGEDFYCVTCHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFV 187 Query: 223 CANCGQEGSDCRCTGAE 239 C C ++ + R T E Sbjct: 188 CVTCSKKLAGQRFTAVE 204 Score = 66.6 bits (161), Expect = 2e-11 Identities = 43/187 (22%), Positives = 69/187 (36%), Gaps = 31/187 (16%) Query: 69 SATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 128 S C+ C + V G ++H+ CF C+ C Q G F+ YC + Sbjct: 98 SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 157 Query: 129 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 188 FA C +C + I I + WH +CF C C + LA F ++ C C+ Sbjct: 158 FAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFV 217 Query: 189 AR----------GLGK----------------YICQKCHAIIDEQPLIFKNDPYHPDHFN 222 A+ G GK + C+KC + + +F H + Sbjct: 218 AKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVF-----HQEQVY 272 Query: 223 CANCGQE 229 C +C ++ Sbjct: 273 CPDCAKK 279 Score = 61.6 bits (148), Expect = 6e-10 Identities = 40/136 (29%), Positives = 56/136 (41%), Gaps = 11/136 (8%) Query: 98 FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 155 F C C + + +G C F A C +C + I + + N WH Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64 Query: 156 CFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIIDEQPLIFK 212 CFRC C LA+ FV + LC C RE K +G K I + +Q + +K Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118 Query: 213 NDPYHPDHFNCANCGQ 228 +H D F C+NC Q Sbjct: 119 GTVWHKDCFTCSNCKQ 134 Score = 37.7 bits (86), Expect = 0.009 Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 7/74 (9%) Query: 155 ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 212 E F C C++ L +V+ G H C C ++ A C +C I D + + +K Sbjct: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 57 Query: 213 NDPYHPDHFNCANC 226 N +H F CA C Sbjct: 58 NRFWHDTCFRCAKC 71 >gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens] Length = 323 Score = 78.6 bits (192), Expect = 5e-15 Identities = 45/197 (22%), Positives = 77/197 (39%), Gaps = 20/197 (10%) Query: 45 HSDVKVYKEFCDFYAKFNMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCF 104 H +K + +FC + TC C+ V+ +H+ CF CA+C Sbjct: 26 HCCLKCFDKFC-------------ANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCL 72 Query: 105 QQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIG--RVIKAMNNSWHPECFRCDLC 162 F + + C +P C C + I+ + ++ WH +CF C C Sbjct: 73 HPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNC 132 Query: 163 QEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFN 222 ++V+ F C CH + A+ C KC+ I + +++ P+H D F Sbjct: 133 KQVIGTGSFFPKGEDFYCVTCHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFV 187 Query: 223 CANCGQEGSDCRCTGAE 239 C C ++ + R T E Sbjct: 188 CVTCSKKLAGQRFTAVE 204 Score = 64.3 bits (155), Expect = 9e-11 Identities = 34/132 (25%), Positives = 53/132 (40%), Gaps = 8/132 (6%) Query: 69 SATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 128 S C+ C + V G ++H+ CF C+ C Q G F+ YC + Sbjct: 98 SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 157 Query: 129 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 188 FA C +C + I I + WH +CF C C + LA F ++ C C+ Sbjct: 158 FAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYK--- 214 Query: 189 ARGLGKYICQKC 200 ++ +KC Sbjct: 215 -----NFVAKKC 221 Score = 61.6 bits (148), Expect = 6e-10 Identities = 40/136 (29%), Positives = 56/136 (41%), Gaps = 11/136 (8%) Query: 98 FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 155 F C C + + +G C F A C +C + I + + N WH Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64 Query: 156 CFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIIDEQPLIFK 212 CFRC C LA+ FV + LC C RE K +G K I + +Q + +K Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118 Query: 213 NDPYHPDHFNCANCGQ 228 +H D F C+NC Q Sbjct: 119 GTVWHKDCFTCSNCKQ 134 Score = 37.7 bits (86), Expect = 0.009 Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 7/74 (9%) Query: 155 ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 212 E F C C++ L +V+ G H C C ++ A C +C I D + + +K Sbjct: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 57 Query: 213 NDPYHPDHFNCANC 226 N +H F CA C Sbjct: 58 NRFWHDTCFRCAKC 71 Score = 33.1 bits (74), Expect = 0.23 Identities = 17/62 (27%), Positives = 27/62 (43%), Gaps = 2/62 (3%) Query: 93 YHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSW 152 +H CFVC C ++ F E + YC ++ A C C I G+ + ++ Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGK--RTVSRVS 238 Query: 153 HP 154 HP Sbjct: 239 HP 240 >gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] Length = 280 Score = 78.6 bits (192), Expect = 5e-15 Identities = 45/197 (22%), Positives = 77/197 (39%), Gaps = 20/197 (10%) Query: 45 HSDVKVYKEFCDFYAKFNMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCF 104 H +K + +FC + TC C+ V+ +H+ CF CA+C Sbjct: 26 HCCLKCFDKFC-------------ANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCL 72 Query: 105 QQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIG--RVIKAMNNSWHPECFRCDLC 162 F + + C +P C C + I+ + ++ WH +CF C C Sbjct: 73 HPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNC 132 Query: 163 QEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFN 222 ++V+ F C CH + A+ C KC+ I + +++ P+H D F Sbjct: 133 KQVIGTGSFFPKGEDFYCVTCHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFV 187 Query: 223 CANCGQEGSDCRCTGAE 239 C C ++ + R T E Sbjct: 188 CVTCSKKLAGQRFTAVE 204 Score = 66.6 bits (161), Expect = 2e-11 Identities = 43/187 (22%), Positives = 69/187 (36%), Gaps = 31/187 (16%) Query: 69 SATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 128 S C+ C + V G ++H+ CF C+ C Q G F+ YC + Sbjct: 98 SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 157 Query: 129 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 188 FA C +C + I I + WH +CF C C + LA F ++ C C+ Sbjct: 158 FAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFV 217 Query: 189 AR----------GLGK----------------YICQKCHAIIDEQPLIFKNDPYHPDHFN 222 A+ G GK + C+KC + + +F H + Sbjct: 218 AKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVF-----HQEQVY 272 Query: 223 CANCGQE 229 C +C ++ Sbjct: 273 CPDCAKK 279 Score = 61.6 bits (148), Expect = 6e-10 Identities = 40/136 (29%), Positives = 56/136 (41%), Gaps = 11/136 (8%) Query: 98 FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 155 F C C + + +G C F A C +C + I + + N WH Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64 Query: 156 CFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIIDEQPLIFK 212 CFRC C LA+ FV + LC C RE K +G K I + +Q + +K Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118 Query: 213 NDPYHPDHFNCANCGQ 228 +H D F C+NC Q Sbjct: 119 GTVWHKDCFTCSNCKQ 134 Score = 37.7 bits (86), Expect = 0.009 Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 7/74 (9%) Query: 155 ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 212 E F C C++ L +V+ G H C C ++ A C +C I D + + +K Sbjct: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 57 Query: 213 NDPYHPDHFNCANC 226 N +H F CA C Sbjct: 58 NRFWHDTCFRCAKC 71 >gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] Length = 309 Score = 78.6 bits (192), Expect = 5e-15 Identities = 45/197 (22%), Positives = 77/197 (39%), Gaps = 20/197 (10%) Query: 45 HSDVKVYKEFCDFYAKFNMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCF 104 H +K + +FC + TC C+ V+ +H+ CF CA+C Sbjct: 55 HCCLKCFDKFC-------------ANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCL 101 Query: 105 QQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIG--RVIKAMNNSWHPECFRCDLC 162 F + + C +P C C + I+ + ++ WH +CF C C Sbjct: 102 HPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNC 161 Query: 163 QEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFN 222 ++V+ F C CH + A+ C KC+ I + +++ P+H D F Sbjct: 162 KQVIGTGSFFPKGEDFYCVTCHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFV 216 Query: 223 CANCGQEGSDCRCTGAE 239 C C ++ + R T E Sbjct: 217 CVTCSKKLAGQRFTAVE 233 Score = 66.6 bits (161), Expect = 2e-11 Identities = 43/187 (22%), Positives = 69/187 (36%), Gaps = 31/187 (16%) Query: 69 SATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 128 S C+ C + V G ++H+ CF C+ C Q G F+ YC + Sbjct: 127 SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 186 Query: 129 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 188 FA C +C + I I + WH +CF C C + LA F ++ C C+ Sbjct: 187 FAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFV 246 Query: 189 AR----------GLGK----------------YICQKCHAIIDEQPLIFKNDPYHPDHFN 222 A+ G GK + C+KC + + +F H + Sbjct: 247 AKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVF-----HQEQVY 301 Query: 223 CANCGQE 229 C +C ++ Sbjct: 302 CPDCAKK 308 Score = 61.6 bits (148), Expect = 6e-10 Identities = 40/136 (29%), Positives = 56/136 (41%), Gaps = 11/136 (8%) Query: 98 FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 155 F C C + + +G C F A C +C + I + + N WH Sbjct: 34 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 93 Query: 156 CFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIIDEQPLIFK 212 CFRC C LA+ FV + LC C RE K +G K I + +Q + +K Sbjct: 94 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 147 Query: 213 NDPYHPDHFNCANCGQ 228 +H D F C+NC Q Sbjct: 148 GTVWHKDCFTCSNCKQ 163 Score = 37.7 bits (86), Expect = 0.009 Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 7/74 (9%) Query: 155 ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 212 E F C C++ L +V+ G H C C ++ A C +C I D + + +K Sbjct: 32 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 86 Query: 213 NDPYHPDHFNCANC 226 N +H F CA C Sbjct: 87 NRFWHDTCFRCAKC 100 >gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] Length = 296 Score = 78.6 bits (192), Expect = 5e-15 Identities = 45/197 (22%), Positives = 77/197 (39%), Gaps = 20/197 (10%) Query: 45 HSDVKVYKEFCDFYAKFNMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCF 104 H +K + +FC + TC C+ V+ +H+ CF CA+C Sbjct: 42 HCCLKCFDKFC-------------ANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCL 88 Query: 105 QQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIG--RVIKAMNNSWHPECFRCDLC 162 F + + C +P C C + I+ + ++ WH +CF C C Sbjct: 89 HPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNC 148 Query: 163 QEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFN 222 ++V+ F C CH + A+ C KC+ I + +++ P+H D F Sbjct: 149 KQVIGTGSFFPKGEDFYCVTCHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFV 203 Query: 223 CANCGQEGSDCRCTGAE 239 C C ++ + R T E Sbjct: 204 CVTCSKKLAGQRFTAVE 220 Score = 66.6 bits (161), Expect = 2e-11 Identities = 43/187 (22%), Positives = 69/187 (36%), Gaps = 31/187 (16%) Query: 69 SATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 128 S C+ C + V G ++H+ CF C+ C Q G F+ YC + Sbjct: 114 SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 173 Query: 129 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 188 FA C +C + I I + WH +CF C C + LA F ++ C C+ Sbjct: 174 FAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFV 233 Query: 189 AR----------GLGK----------------YICQKCHAIIDEQPLIFKNDPYHPDHFN 222 A+ G GK + C+KC + + +F H + Sbjct: 234 AKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVF-----HQEQVY 288 Query: 223 CANCGQE 229 C +C ++ Sbjct: 289 CPDCAKK 295 Score = 61.6 bits (148), Expect = 6e-10 Identities = 40/136 (29%), Positives = 56/136 (41%), Gaps = 11/136 (8%) Query: 98 FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 155 F C C + + +G C F A C +C + I + + N WH Sbjct: 21 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80 Query: 156 CFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIIDEQPLIFK 212 CFRC C LA+ FV + LC C RE K +G K I + +Q + +K Sbjct: 81 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 134 Query: 213 NDPYHPDHFNCANCGQ 228 +H D F C+NC Q Sbjct: 135 GTVWHKDCFTCSNCKQ 150 Score = 37.7 bits (86), Expect = 0.009 Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 7/74 (9%) Query: 155 ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 212 E F C C++ L +V+ G H C C ++ A C +C I D + + +K Sbjct: 19 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 73 Query: 213 NDPYHPDHFNCANC 226 N +H F CA C Sbjct: 74 NRFWHDTCFRCAKC 87 >gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] Length = 280 Score = 78.6 bits (192), Expect = 5e-15 Identities = 45/197 (22%), Positives = 77/197 (39%), Gaps = 20/197 (10%) Query: 45 HSDVKVYKEFCDFYAKFNMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCF 104 H +K + +FC + TC C+ V+ +H+ CF CA+C Sbjct: 26 HCCLKCFDKFC-------------ANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCL 72 Query: 105 QQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIG--RVIKAMNNSWHPECFRCDLC 162 F + + C +P C C + I+ + ++ WH +CF C C Sbjct: 73 HPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNC 132 Query: 163 QEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFN 222 ++V+ F C CH + A+ C KC+ I + +++ P+H D F Sbjct: 133 KQVIGTGSFFPKGEDFYCVTCHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFV 187 Query: 223 CANCGQEGSDCRCTGAE 239 C C ++ + R T E Sbjct: 188 CVTCSKKLAGQRFTAVE 204 Score = 66.6 bits (161), Expect = 2e-11 Identities = 43/187 (22%), Positives = 69/187 (36%), Gaps = 31/187 (16%) Query: 69 SATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 128 S C+ C + V G ++H+ CF C+ C Q G F+ YC + Sbjct: 98 SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 157 Query: 129 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 188 FA C +C + I I + WH +CF C C + LA F ++ C C+ Sbjct: 158 FAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFV 217 Query: 189 AR----------GLGK----------------YICQKCHAIIDEQPLIFKNDPYHPDHFN 222 A+ G GK + C+KC + + +F H + Sbjct: 218 AKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVF-----HQEQVY 272 Query: 223 CANCGQE 229 C +C ++ Sbjct: 273 CPDCAKK 279 Score = 61.6 bits (148), Expect = 6e-10 Identities = 40/136 (29%), Positives = 56/136 (41%), Gaps = 11/136 (8%) Query: 98 FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 155 F C C + + +G C F A C +C + I + + N WH Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64 Query: 156 CFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIIDEQPLIFK 212 CFRC C LA+ FV + LC C RE K +G K I + +Q + +K Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118 Query: 213 NDPYHPDHFNCANCGQ 228 +H D F C+NC Q Sbjct: 119 GTVWHKDCFTCSNCKQ 134 Score = 37.7 bits (86), Expect = 0.009 Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 7/74 (9%) Query: 155 ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 212 E F C C++ L +V+ G H C C ++ A C +C I D + + +K Sbjct: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 57 Query: 213 NDPYHPDHFNCANC 226 N +H F CA C Sbjct: 58 NRFWHDTCFRCAKC 71 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.326 0.140 0.472 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,668,886 Number of Sequences: 37866 Number of extensions: 504600 Number of successful extensions: 2870 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 129 Number of HSP's successfully gapped in prelim test: 121 Number of HSP's that attempted gapping in prelim test: 1954 Number of HSP's gapped (non-prelim): 678 length of query: 248 length of database: 18,247,518 effective HSP length: 100 effective length of query: 148 effective length of database: 14,460,918 effective search space: 2140215864 effective search space used: 2140215864 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.