Guide to the Human Genome
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Search of human proteins with 239049457

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239049457 FCH domain only 1 isoform b [Homo sapiens]
         (889 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239049457 FCH domain only 1 isoform b [Homo sapiens]              1786   0.0  
gi|29789054 FCH domain only 1 isoform b [Homo sapiens]               1786   0.0  
gi|239049440 FCH domain only 1 isoform a [Homo sapiens]              1771   0.0  
gi|239049540 FCH domain only 1 isoform c [Homo sapiens]              1682   0.0  
gi|226371723 FCH domain only 2 isoform a [Homo sapiens]               736   0.0  
gi|226371725 FCH domain only 2 isoform b [Homo sapiens]               684   0.0  
gi|116235472 SH3-domain GRB2-like (endophilin) interacting prote...   312   8e-85
gi|20149528 proline-serine-threonine phosphatase interacting pro...    95   3e-19
gi|165905601 proline-serine-threonine phosphatase interacting pr...    90   8e-18
gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens]         88   4e-17
gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens]          88   4e-17
gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens]          88   4e-17
gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens]          88   4e-17
gi|19224660 protein kinase C and casein kinase substrate in neur...    57   6e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    55   2e-07
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             55   3e-07
gi|116256464 hypothetical protein LOC343990 [Homo sapiens]             54   6e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni...    54   6e-07
gi|157168329 formin 1 [Homo sapiens]                                   53   1e-06
gi|239752265 PREDICTED: hypothetical protein XP_002348186 [Homo ...    52   3e-06
gi|51702222 SPT2, Suppressor of Ty, domain containing 1 [Homo sa...    51   5e-06
gi|157743252 pecanex-like 3 [Homo sapiens]                             50   7e-06
gi|18959210 WIRE protein [Homo sapiens]                                50   7e-06
gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s...    50   9e-06
gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sa...    50   9e-06
gi|157074225 nuclear pore complex interacting protein-like 3 [Ho...    50   9e-06
gi|150170670 piccolo isoform 2 [Homo sapiens]                          50   1e-05
gi|150378539 piccolo isoform 1 [Homo sapiens]                          50   1e-05
gi|33356148 formin-like 1 [Homo sapiens]                               49   2e-05
gi|223972704 hypothetical protein LOC284418 [Homo sapiens]             49   3e-05

>gi|239049457 FCH domain only 1 isoform b [Homo sapiens]
          Length = 889

 Score = 1786 bits (4625), Expect = 0.0
 Identities = 889/889 (100%), Positives = 889/889 (100%)

Query: 1   MSYFGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASN 60
           MSYFGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASN
Sbjct: 1   MSYFGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASN 60

Query: 61  GTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVST 120
           GTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVST
Sbjct: 61  GTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVST 120

Query: 121 LDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKKAAESLRRSVE 180
           LDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKKAAESLRRSVE
Sbjct: 121 LDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKKAAESLRRSVE 180

Query: 181 KYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNI 240
           KYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNI
Sbjct: 181 KYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNI 240

Query: 241 ENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRRERE 300
           ENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRRERE
Sbjct: 241 ENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRRERE 300

Query: 301 PEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVH 360
           PEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVH
Sbjct: 301 PEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVH 360

Query: 361 IKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSS 420
           IKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSS
Sbjct: 361 IKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSS 420

Query: 421 CAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSP 480
           CAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSP
Sbjct: 421 CAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSP 480

Query: 481 SHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALA 540
           SHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALA
Sbjct: 481 SHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALA 540

Query: 541 GGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTALER 600
           GGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTALER
Sbjct: 541 GGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTALER 600

Query: 601 PSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLARVTGELTMTFP 660
           PSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLARVTGELTMTFP
Sbjct: 601 PSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLARVTGELTMTFP 660

Query: 661 AGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEA 720
           AGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEA
Sbjct: 661 AGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEA 720

Query: 721 LQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYGYRPGATA 780
           LQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYGYRPGATA
Sbjct: 721 LQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYGYRPGATA 780

Query: 781 VPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSGRLSASWEPLS 840
           VPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSGRLSASWEPLS
Sbjct: 781 VPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSGRLSASWEPLS 840

Query: 841 GPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC 889
           GPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC
Sbjct: 841 GPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC 889


>gi|29789054 FCH domain only 1 isoform b [Homo sapiens]
          Length = 889

 Score = 1786 bits (4625), Expect = 0.0
 Identities = 889/889 (100%), Positives = 889/889 (100%)

Query: 1   MSYFGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASN 60
           MSYFGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASN
Sbjct: 1   MSYFGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASN 60

Query: 61  GTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVST 120
           GTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVST
Sbjct: 61  GTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVST 120

Query: 121 LDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKKAAESLRRSVE 180
           LDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKKAAESLRRSVE
Sbjct: 121 LDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKKAAESLRRSVE 180

Query: 181 KYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNI 240
           KYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNI
Sbjct: 181 KYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNI 240

Query: 241 ENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRRERE 300
           ENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRRERE
Sbjct: 241 ENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRRERE 300

Query: 301 PEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVH 360
           PEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVH
Sbjct: 301 PEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVH 360

Query: 361 IKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSS 420
           IKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSS
Sbjct: 361 IKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSS 420

Query: 421 CAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSP 480
           CAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSP
Sbjct: 421 CAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSP 480

Query: 481 SHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALA 540
           SHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALA
Sbjct: 481 SHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALA 540

Query: 541 GGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTALER 600
           GGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTALER
Sbjct: 541 GGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTALER 600

Query: 601 PSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLARVTGELTMTFP 660
           PSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLARVTGELTMTFP
Sbjct: 601 PSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLARVTGELTMTFP 660

Query: 661 AGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEA 720
           AGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEA
Sbjct: 661 AGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEA 720

Query: 721 LQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYGYRPGATA 780
           LQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYGYRPGATA
Sbjct: 721 LQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYGYRPGATA 780

Query: 781 VPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSGRLSASWEPLS 840
           VPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSGRLSASWEPLS
Sbjct: 781 VPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSGRLSASWEPLS 840

Query: 841 GPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC 889
           GPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC
Sbjct: 841 GPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC 889


>gi|239049440 FCH domain only 1 isoform a [Homo sapiens]
          Length = 891

 Score = 1771 bits (4586), Expect = 0.0
 Identities = 882/882 (100%), Positives = 882/882 (100%)

Query: 1   MSYFGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASN 60
           MSYFGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASN
Sbjct: 1   MSYFGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASN 60

Query: 61  GTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVST 120
           GTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVST
Sbjct: 61  GTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVST 120

Query: 121 LDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKKAAESLRRSVE 180
           LDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKKAAESLRRSVE
Sbjct: 121 LDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKKAAESLRRSVE 180

Query: 181 KYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNI 240
           KYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNI
Sbjct: 181 KYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNI 240

Query: 241 ENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRRERE 300
           ENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRRERE
Sbjct: 241 ENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRRERE 300

Query: 301 PEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVH 360
           PEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVH
Sbjct: 301 PEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVH 360

Query: 361 IKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSS 420
           IKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSS
Sbjct: 361 IKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSS 420

Query: 421 CAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSP 480
           CAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSP
Sbjct: 421 CAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSP 480

Query: 481 SHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALA 540
           SHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALA
Sbjct: 481 SHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALA 540

Query: 541 GGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTALER 600
           GGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTALER
Sbjct: 541 GGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTALER 600

Query: 601 PSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLARVTGELTMTFP 660
           PSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLARVTGELTMTFP
Sbjct: 601 PSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLARVTGELTMTFP 660

Query: 661 AGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEA 720
           AGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEA
Sbjct: 661 AGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEA 720

Query: 721 LQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYGYRPGATA 780
           LQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYGYRPGATA
Sbjct: 721 LQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYGYRPGATA 780

Query: 781 VPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSGRLSASWEPLS 840
           VPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSGRLSASWEPLS
Sbjct: 781 VPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSGRLSASWEPLS 840

Query: 841 GPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFAT 882
           GPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFAT
Sbjct: 841 GPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFAT 882


>gi|239049540 FCH domain only 1 isoform c [Homo sapiens]
          Length = 839

 Score = 1682 bits (4356), Expect = 0.0
 Identities = 839/839 (100%), Positives = 839/839 (100%)

Query: 51  MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH 110
           MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH
Sbjct: 1   MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH 60

Query: 111 KKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKK 170
           KKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKK
Sbjct: 61  KKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKK 120

Query: 171 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 230
           AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG
Sbjct: 121 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 180

Query: 231 QVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFR 290
           QVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFR
Sbjct: 181 QVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFR 240

Query: 291 LPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFD 350
           LPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFD
Sbjct: 241 LPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFD 300

Query: 351 DEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQ 410
           DEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQ
Sbjct: 301 DEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQ 360

Query: 411 RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPE 470
           RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPE
Sbjct: 361 RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPE 420

Query: 471 NVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASS 530
           NVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASS
Sbjct: 421 NVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASS 480

Query: 531 PGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG 590
           PGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG
Sbjct: 481 PGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG 540

Query: 591 SSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLAR 650
           SSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLAR
Sbjct: 541 SSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLAR 600

Query: 651 VTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDF 710
           VTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDF
Sbjct: 601 VTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDF 660

Query: 711 WLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSV 770
           WLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSV
Sbjct: 661 WLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSV 720

Query: 771 EYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSG 830
           EYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSG
Sbjct: 721 EYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSG 780

Query: 831 RLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC 889
           RLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC
Sbjct: 781 RLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC 839


>gi|226371723 FCH domain only 2 isoform a [Homo sapiens]
          Length = 810

 Score =  736 bits (1901), Expect = 0.0
 Identities = 404/897 (45%), Positives = 568/897 (63%), Gaps = 97/897 (10%)

Query: 1   MSYFGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASN 60
           M+YF E+FWGEKN GF+VLYH++K G ISTKELADF+RERATIEE YS++M KL+K ASN
Sbjct: 3   MAYFVENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASN 62

Query: 61  GTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVST 120
            + +GTFAP+W+VF+ S++KLA CHL+L RKLQ+LIK+V +YGEEQ+K+HKK KEEV  T
Sbjct: 63  YSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGT 122

Query: 121 LDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKKAAESLRRSVE 180
           L+AVQ +  ++Q L KS+ENY  +C++QERL++E  +Q+E++KA  K+KKA ++ +  VE
Sbjct: 123 LEAVQTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKKATDTYKLYVE 182

Query: 181 KYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNI 240
           KY  A+ADFEQKM ++A +FQ +EETHL H+K ++GS ++++++ H+QIGQVHEEF  N+
Sbjct: 183 KYALAKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNAIKEIHLQIGQVHEEFINNM 242

Query: 241 ENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRRERE 300
            N +VE L++KFAESKGTG+E+PG ++FE    A+  E +K  R  K F LPG+ ++E++
Sbjct: 243 ANTTVESLIQKFAESKGTGKERPGLIEFEECDTASAVEGIKP-RKRKTFALPGIIKKEKD 301

Query: 301 PEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVH 360
            E   +V+  + DS   P+VDEEG++++P+  QN T E   +SSSDSD +DEEP+K+ + 
Sbjct: 302 AE---SVECPDADSLNIPDVDEEGYSIKPETNQNDTKENHFYSSSDSDSEDEEPKKYRIE 358

Query: 361 IKPAPARAPACSPEAAAAQLRATAGSLILPPGPGG----TMKRHSSRDAAGKPQRPRSAP 416
           IKP      +    A+  +L+ + G++ L P         M R+ S +   K  +P + P
Sbjct: 359 IKPMHPN-NSHHTMASLDELKVSIGNITLSPAISRHSPVQMNRNLSNEELTK-SKPSAPP 416

Query: 417 RTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSG 476
                ++ L  +      LFGP L+S         SSS   TSS S              
Sbjct: 417 NEKGTSDLLAWDP-----LFGPSLDS---------SSSSSLTSSSS-------------- 448

Query: 477 LDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGL 536
                             RP TP S  +          I  PP P S   L S       
Sbjct: 449 -----------------ARPTTPLSVGT----------IVPPPRPASRPKLTSG------ 475

Query: 537 EALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAAST 596
             L+G + +P P  P      + PP        + PL R+        S S + SSA+ +
Sbjct: 476 -KLSGINEIPRPFSPPVTSNTSPPP--------AAPLARAE-------SSSSISSSASLS 519

Query: 597 ALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPS-CLARVTGEL 655
           A   P+       GVSRGPSPV LG+QD LP+A A TE V+AYF+G  P+ C+ ++TG++
Sbjct: 520 AANTPTV------GVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPTKCIVKITGDM 573

Query: 656 TMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMA 715
           TM+FP+GI++VF+  P P VL FR+ + + +E   PNA L+FSDPSQ D  TKDFW+NM 
Sbjct: 574 TMSFPSGIIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLVFSDPSQCDSNTKDFWMNMQ 633

Query: 716 ALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYGYR 775
           A+T  L++ +EQNP ASYYNV +L+YQ S  G QS PL L+ +W+C A+ T + V+Y Y 
Sbjct: 634 AVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSASTTDLRVDYKYN 693

Query: 776 PGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEA---GGSGRL 832
           P A   P+ L+N+Q+++PV   VTN++  P A WN E+ +  W+L  +SE    GGSG L
Sbjct: 694 PEAMVAPSVLSNIQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSSISEKSENGGSGSL 753

Query: 833 SASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC 889
            A ++   GPS P+ +A QF SEG+TLSGVD ELVG+GYR+SL+K+RFATG YL  C
Sbjct: 754 RAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFATGRYLADC 810


>gi|226371725 FCH domain only 2 isoform b [Homo sapiens]
          Length = 777

 Score =  684 bits (1765), Expect = 0.0
 Identities = 389/897 (43%), Positives = 541/897 (60%), Gaps = 130/897 (14%)

Query: 1   MSYFGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASN 60
           M+YF E+FWGEKN GF+VLYH++K G ISTKELADF+RERATIEE YS++M KL+K ASN
Sbjct: 3   MAYFVENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASN 62

Query: 61  GTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVST 120
            + +GTFAP+W+VF+ S++KLA CHL+L RKLQ+LIK+V +YGEEQ+K+HKK KEEV  T
Sbjct: 63  YSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGT 122

Query: 121 LDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKKAAESLRRSVE 180
           L+AVQ +  ++Q L KS+ENY  +C++QERL++E  +Q+E++KA  K+KKA ++ +  VE
Sbjct: 123 LEAVQTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKKATDTYKLYVE 182

Query: 181 KYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNI 240
           KY  A+ADFEQKM ++A                                 QVHEEF  N+
Sbjct: 183 KYALAKADFEQKMTETA---------------------------------QVHEEFINNM 209

Query: 241 ENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRRERE 300
            N +VE L++KFAESKGTG+E+PG ++FE    A+  E +K  R  K F LPG+ ++E++
Sbjct: 210 ANTTVESLIQKFAESKGTGKERPGLIEFEECDTASAVEGIKP-RKRKTFALPGIIKKEKD 268

Query: 301 PEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVH 360
            E   +V+  + DS   P+VDEEG++++P+  QN T E   +SSSDSD +DEEP+K+ + 
Sbjct: 269 AE---SVECPDADSLNIPDVDEEGYSIKPETNQNDTKENHFYSSSDSDSEDEEPKKYRIE 325

Query: 361 IKPAPARAPACSPEAAAAQLRATAGSLILPPGPGG----TMKRHSSRDAAGKPQRPRSAP 416
           IKP      +    A+  +L+ + G++ L P         M R+ S +   K  +P + P
Sbjct: 326 IKPMHPNN-SHHTMASLDELKVSIGNITLSPAISRHSPVQMNRNLSNEELTK-SKPSAPP 383

Query: 417 RTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSG 476
                ++ L  +      LFGP L+S         SSS   TSS S              
Sbjct: 384 NEKGTSDLLAWDP-----LFGPSLDS---------SSSSSLTSSSSA------------- 416

Query: 477 LDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGL 536
                             RP TP S  +          I  PP P S   L S       
Sbjct: 417 ------------------RPTTPLSVGT----------IVPPPRPASRPKLTSGK----- 443

Query: 537 EALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAAST 596
             L+G + +P P  P      + PP        + PL R+        S S + SSA+ +
Sbjct: 444 --LSGINEIPRPFSPPVTSNTSPPP--------AAPLARAE-------SSSSISSSASLS 486

Query: 597 ALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPS-CLARVTGEL 655
           A   P+       GVSRGPSPV LG+QD LP+A A TE V+AYF+G  P+ C+ ++TG++
Sbjct: 487 AANTPTV------GVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPTKCIVKITGDM 540

Query: 656 TMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMA 715
           TM+FP+GI++VF+  P P VL FR+ + + +E   PNA L+FSDPSQ D  TKDFW+NM 
Sbjct: 541 TMSFPSGIIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLVFSDPSQCDSNTKDFWMNMQ 600

Query: 716 ALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYGYR 775
           A+T  L++ +EQNP ASYYNV +L+YQ S  G QS PL L+ +W+C A+ T + V+Y Y 
Sbjct: 601 AVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSASTTDLRVDYKYN 660

Query: 776 PGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEA---GGSGRL 832
           P A   P+ L+N+Q+++PV   VTN++  P A WN E+ +  W+L  +SE    GGSG L
Sbjct: 661 PEAMVAPSVLSNIQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSSISEKSENGGSGSL 720

Query: 833 SASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC 889
            A ++   GPS P+ +A QF SEG+TLSGVD ELVG+GYR+SL+K+RFATG YL  C
Sbjct: 721 RAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFATGRYLADC 777


>gi|116235472 SH3-domain GRB2-like (endophilin) interacting protein
           1 [Homo sapiens]
          Length = 828

 Score =  312 bits (800), Expect = 8e-85
 Identities = 201/548 (36%), Positives = 288/548 (52%), Gaps = 47/548 (8%)

Query: 349 FDDEEPRKFYVHIKPAP-ARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAG 407
           F D  P      + P     +P  +P+  A    + A   + PPGP G           G
Sbjct: 315 FSDTSPEHVTPELTPREKVVSPPATPDNPAD---SPAPGPLGPPGPTGP---------PG 362

Query: 408 KPQRPRS--APRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFS 465
            P  PR+  +P      ++  +E+   K+ +   LE+    +DF     LG  ++P P  
Sbjct: 363 PPGPPRNVLSPLNLEEVQKKVAEQTFIKDDY---LETISSPKDF----GLGQRATPPP-- 413

Query: 466 SSSPENVEDSGLDSPSHAA-PGPSPDSWVPRPGTPQSP-PSCRAPPPEARGIRAPPLPDS 523
              P     + + SP   + PGP   S    P  P +P   CR+  P       PP P  
Sbjct: 414 --PPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPP------PPPPRP 465

Query: 524 PQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRS 583
           P      PG  G+     GD+   P  P      + PP    +R  S     S   LS +
Sbjct: 466 PSRPKLPPGKPGV-----GDVS-RPFSPPIHSS-SPPPIAPLARAESTSSISSTNSLSAA 518

Query: 584 LSPSPLGSSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGH 643
            +P+      +    +R  F   T  G SRGPSP+ +G+QD LP+A AFTE V+AYF+G 
Sbjct: 519 TTPTVENEQPSLVWFDRGKFYL-TFEGSSRGPSPLTMGAQDTLPVAAAFTETVNAYFKGA 577

Query: 644 SPS-CLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQ 702
            PS C+ ++TGE+ ++FPAGI R F+  P P  L+FR+++ + +EH  PN  LL  D +Q
Sbjct: 578 DPSKCIVKITGEMVLSFPAGITRHFANNPSPAALTFRVINFSRLEHVLPNPQLLCCDNTQ 637

Query: 703 SDPETKDFWLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCG 762
           +D  TK+FW+NM  L   L++ +EQ P A+YYNV +L+YQ S  G QS PL L+ +W+C 
Sbjct: 638 NDANTKEFWVNMPNLMTHLKKVSEQKPQATYYNVDMLKYQVSAQGIQSTPLNLAVNWRCE 697

Query: 763 ATLTQVSVEYGYRPGATAVPTPLTNVQILLPVGEPVTNVR-LQPAATWNLEEKRLTWRLP 821
            + T + ++Y Y   A      L NVQ L+P+   VT ++ + P A WN E++R+ W++P
Sbjct: 698 PSSTDLRIDYKYNTDAMTTAVALNNVQFLVPIDGGVTKLQAVLPPAVWNAEQQRILWKIP 757

Query: 822 DV---SEAGGSGRLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKR 878
           D+   SE GG G L A ++   GPS PSP+  QFTSEG+TLSG D+ELVG+GYR SL+K+
Sbjct: 758 DISQKSENGGVGSLLARFQLSEGPSKPSPLVVQFTSEGSTLSGCDIELVGAGYRFSLIKK 817

Query: 879 RFATGMYL 886
           RFA G YL
Sbjct: 818 RFAAGKYL 825



 Score = 84.3 bits (207), Expect = 4e-16
 Identities = 81/294 (27%), Positives = 127/294 (43%), Gaps = 40/294 (13%)

Query: 318 PEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPACSPEAAA 377
           PE+DEEG+++RP+    ST     +SSS+S+ ++E  +KF + IKP  ++       A  
Sbjct: 79  PELDEEGYSIRPE-EPGSTKGKHFYSSSESEEEEESHKKFNIKIKPLQSK-DILKNAATV 136

Query: 378 AQLRATAGSLILPPGP--------GGTMKRHSSRDAAGKPQRPRSAPRTSSCAERLQSEE 429
            +L+A+ G++ L P P         G +KR+ S +   +P+R  S P     +++   + 
Sbjct: 137 DELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPRR--STPTPELISKKPPDDT 194

Query: 430 QVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSP 489
                LFGPPLESAFD +      +      P  + S  P N     ++SP    P P  
Sbjct: 195 TALAPLFGPPLESAFDEQ-----KTEVLLDQPEIWGSGQPIN---PSMESPKLTRPFP-- 244

Query: 490 DSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPD---SPQPLASSPGPWGLEALAGGDLMP 546
            +  P P  P++ P+   PP     +   P  D   +   +   P    L+++ G  L P
Sbjct: 245 -TGTPPPLPPKNVPA--TPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGPVLSP 301

Query: 547 APADPTAREGL----------AAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLG 590
                 A E              P    R + VS P T  N   + S +P PLG
Sbjct: 302 KSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNP--ADSPAPGPLG 353


>gi|20149528 proline-serine-threonine phosphatase interacting
           protein 1 [Homo sapiens]
          Length = 416

 Score = 94.7 bits (234), Expect = 3e-19
 Identities = 63/285 (22%), Positives = 140/285 (49%), Gaps = 21/285 (7%)

Query: 4   FGEHFWGEK---NHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASN 60
           F + FW      + G+EVL   +  G    K++ + +R+RA  EE Y K + ++++ A  
Sbjct: 7   FKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARKAGG 66

Query: 61  GTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVST 120
            T + +    ++  +   + +   H++L   L++ ++ +  + E Q +  KK +    + 
Sbjct: 67  QTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYE----AV 122

Query: 121 LDAVQVLS-GVSQLLPKSRENYLNRCMD----QERLRRESTS--QKEMDKAETKTKKAAE 173
           +D VQ     + +   +S++ Y  +C D    ++   R S +  QK+++K++ K ++  +
Sbjct: 123 MDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQCKD 182

Query: 174 SL-------RRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTH 226
           S        R+S+ +    RA++EQ+   +   FQ  E   L  ++  L  +++ +    
Sbjct: 183 SATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQC 242

Query: 227 VQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAY 271
           V+  +++EE +  +E  S++  +  F ++K TG E P P+ ++ Y
Sbjct: 243 VKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNY 287


>gi|165905601 proline-serine-threonine phosphatase interacting
           protein 2 [Homo sapiens]
          Length = 334

 Score = 90.1 bits (222), Expect = 8e-18
 Identities = 70/324 (21%), Positives = 146/324 (45%), Gaps = 25/324 (7%)

Query: 2   SYFGEHFWGE---KNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLA 58
           S F  +FW        G++ +   +  G  + KE  DF++ERA IEE Y K +  LS+  
Sbjct: 4   SLFKGNFWSADILSTIGYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKK 63

Query: 59  SNG-TPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEV 117
             G + + T     EVF+   D +A CH++L + L++  + +  + E+Q K  +K  E +
Sbjct: 64  PCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQ-KLQRKKTELI 122

Query: 118 VSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRR------ESTSQKEMDKAETKTKKA 171
           +  +   + L     +   +++NY  +C D++   +         + K+ +K   K   +
Sbjct: 123 MDAIHKQKSLQFKKTM--DAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATS 180

Query: 172 AESLRRSVEKY-------NSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVED 224
             ++  S + Y       +  R +++ + + +   F+A E   +   +  L  + + +  
Sbjct: 181 KTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQ 240

Query: 225 THVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLR 284
             V   +++E+ ++++E  S++  +  F   + TG+  P P+ +E +       + K   
Sbjct: 241 QCVTSDEMYEQVRKSLEMCSIQRDIEYFVNQRKTGQIPPAPIMYENF-----YSSQKNAV 295

Query: 285 GAKAFRLPGLSRREREPEPPAAVD 308
            A     P L+RR   P P ++ D
Sbjct: 296 PAGKATGPNLARRGPLPIPKSSPD 319


>gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens]
          Length = 412

 Score = 87.8 bits (216), Expect = 4e-17
 Identities = 69/266 (25%), Positives = 125/266 (46%), Gaps = 27/266 (10%)

Query: 6   EHFWGEKNH--------GFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKL 57
           ++FW +K          GFE+L     +G    KE+++FIRER  IEE Y+K +AKLS+ 
Sbjct: 138 DYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQN 197

Query: 58  ASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKL-QDLIKDVLRYGEEQLKTHKKCKEE 116
           +      G+    W   + S    A  HL+ + KL  ++ K ++ + E   K  KKC   
Sbjct: 198 SLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHH 257

Query: 117 VVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQE------RLRRESTSQKEMDKAETKTKK 170
           +    D  + L+     + K+R+    R  D E       ++  + +++++ KA  K+ +
Sbjct: 258 IA---DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQ 314

Query: 171 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 230
           A + L R V+ YN A++ + ++M+ + L  + +E   +  ++  L  Y     +T     
Sbjct: 315 AGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHET----- 369

Query: 231 QVHEEFKQNIENVSVEMLLRKFAESK 256
              + F Q+     V+ LLRK   +K
Sbjct: 370 ---DMFNQSTVE-PVDQLLRKVDPAK 391


>gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens]
          Length = 476

 Score = 87.8 bits (216), Expect = 4e-17
 Identities = 69/266 (25%), Positives = 125/266 (46%), Gaps = 27/266 (10%)

Query: 6   EHFWGEKNH--------GFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKL 57
           ++FW +K          GFE+L     +G    KE+++FIRER  IEE Y+K +AKLS+ 
Sbjct: 202 DYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQN 261

Query: 58  ASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKL-QDLIKDVLRYGEEQLKTHKKCKEE 116
           +      G+    W   + S    A  HL+ + KL  ++ K ++ + E   K  KKC   
Sbjct: 262 SLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHH 321

Query: 117 VVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQE------RLRRESTSQKEMDKAETKTKK 170
           +    D  + L+     + K+R+    R  D E       ++  + +++++ KA  K+ +
Sbjct: 322 IA---DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQ 378

Query: 171 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 230
           A + L R V+ YN A++ + ++M+ + L  + +E   +  ++  L  Y     +T     
Sbjct: 379 AGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHET----- 433

Query: 231 QVHEEFKQNIENVSVEMLLRKFAESK 256
              + F Q+     V+ LLRK   +K
Sbjct: 434 ---DMFNQSTVE-PVDQLLRKVDPAK 455


>gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens]
          Length = 416

 Score = 87.8 bits (216), Expect = 4e-17
 Identities = 69/266 (25%), Positives = 125/266 (46%), Gaps = 27/266 (10%)

Query: 6   EHFWGEKNH--------GFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKL 57
           ++FW +K          GFE+L     +G    KE+++FIRER  IEE Y+K +AKLS+ 
Sbjct: 142 DYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQN 201

Query: 58  ASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKL-QDLIKDVLRYGEEQLKTHKKCKEE 116
           +      G+    W   + S    A  HL+ + KL  ++ K ++ + E   K  KKC   
Sbjct: 202 SLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHH 261

Query: 117 VVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQE------RLRRESTSQKEMDKAETKTKK 170
           +    D  + L+     + K+R+    R  D E       ++  + +++++ KA  K+ +
Sbjct: 262 IA---DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQ 318

Query: 171 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 230
           A + L R V+ YN A++ + ++M+ + L  + +E   +  ++  L  Y     +T     
Sbjct: 319 AGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHET----- 373

Query: 231 QVHEEFKQNIENVSVEMLLRKFAESK 256
              + F Q+     V+ LLRK   +K
Sbjct: 374 ---DMFNQSTVE-PVDQLLRKVDPAK 395


>gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens]
          Length = 336

 Score = 87.8 bits (216), Expect = 4e-17
 Identities = 69/266 (25%), Positives = 125/266 (46%), Gaps = 27/266 (10%)

Query: 6   EHFWGEKNH--------GFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKL 57
           ++FW +K          GFE+L     +G    KE+++FIRER  IEE Y+K +AKLS+ 
Sbjct: 62  DYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQN 121

Query: 58  ASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKL-QDLIKDVLRYGEEQLKTHKKCKEE 116
           +      G+    W   + S    A  HL+ + KL  ++ K ++ + E   K  KKC   
Sbjct: 122 SLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHH 181

Query: 117 VVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQE------RLRRESTSQKEMDKAETKTKK 170
           +    D  + L+     + K+R+    R  D E       ++  + +++++ KA  K+ +
Sbjct: 182 IA---DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQ 238

Query: 171 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 230
           A + L R V+ YN A++ + ++M+ + L  + +E   +  ++  L  Y     +T     
Sbjct: 239 AGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHET----- 293

Query: 231 QVHEEFKQNIENVSVEMLLRKFAESK 256
              + F Q+     V+ LLRK   +K
Sbjct: 294 ---DMFNQSTVE-PVDQLLRKVDPAK 315


>gi|19224660 protein kinase C and casein kinase substrate in neurons
           3 [Homo sapiens]
          Length = 424

 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 80/382 (20%), Positives = 132/382 (34%), Gaps = 63/382 (16%)

Query: 5   GEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSK----LASN 60
           G  FW   N+   V    V+ G     +L    +ERA IE+ Y++ +A  ++        
Sbjct: 13  GGSFWEAGNYRRTV--QRVEDGHRLCGDLVSCFQERARIEKAYAQQLADWARKWRGTVEK 70

Query: 61  GTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLR------------------- 101
           G   GT    W  F  ++++L+  HLE+  KLQ    + +R                   
Sbjct: 71  GPQYGTLEKAWHAFFTAAERLSALHLEVREKLQGQDSERVRAWQRGAFHRPVLGGFRESR 130

Query: 102 -----YGEEQLKTHKKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRREST 156
                + + Q    K+ KE   S                +      +  + QE+LR+   
Sbjct: 131 AAEDGFRKAQKPWLKRLKEVEASKKSYHAARKDEKTAQTRESHAKADSAVSQEQLRKLQE 190

Query: 157 SQKEMDKAETKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMK-ALL 215
             +   K   KTK   E     + +Y     +  ++  ++    QA E   L   K  LL
Sbjct: 191 RVERCAKEAEKTKAQYEQTLAELHRYTPRYMEDMEQAFETC---QAAERQRLLFFKDMLL 247

Query: 216 GSYAHSVEDTHVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAA 275
             + H    +  +  ++H +  Q IE  S E  LR +  + G G     P  FE +S   
Sbjct: 248 TLHQHLDLSSSEKFHELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWP-QFEEWSLDT 306

Query: 276 LQEAMKRLRGAKAFRLPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNS 335
            +   ++ +G             R P+       +    GT P     G           
Sbjct: 307 QRTISRKEKGG------------RSPDEVTLTSIVPTRDGTAPPPQSPG----------- 343

Query: 336 TAEPSRFSSSDSDFDDEE-PRK 356
               S  +  D ++ DEE PRK
Sbjct: 344 ----SPGTGQDEEWSDEESPRK 361


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 141/575 (24%), Positives = 204/575 (35%), Gaps = 77/575 (13%)

Query: 303 PPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVHIK 362
           PP  V    P S T P +      +     Q +T+  S    +   F    PR+    + 
Sbjct: 387 PPIQV----PHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLT 442

Query: 363 PAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCA 422
            +P+R  +  P++   Q       L LP  P        +      P         SS A
Sbjct: 443 -SPSRPASTPPDSPPLQ-----APLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLA 496

Query: 423 ERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVED--SGLDSP 480
               S +    +L  PPLE+          SSL   S  +P +S +   +E+  S    P
Sbjct: 497 SH--SPQAPLSSLIMPPLET---------QSSLAPPSLQTPPASLTTPPLENLPSLAPPP 545

Query: 481 SHAAPGPSPDSWVPRPGTP-----QSPPS-CRAPPPEARGIRAPPLPDSPQPLASSPGPW 534
              A  P     +  P  P     Q+PPS    PPPE     A P P +P  LAS P   
Sbjct: 546 LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP--- 602

Query: 535 GLEALAGGDLMP-APADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSA 593
            L+ L    L P A   P A   LA PP +      + P   ++  LS   +PSP   +A
Sbjct: 603 -LQGLPSPPLSPLATPPPQAPPXLALPPLQ------APPSPPASPPLSPLATPSPQAPNA 655

Query: 594 ASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLARVTG 653
            +  L +  F       V    SP    S    P AT  ++         +P  LA    
Sbjct: 656 LAVHLLQAPFSPPPSPPVQAPFSPP--ASPPVSPSATPPSQ---------APPSLAAPPL 704

Query: 654 ELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLN 713
           ++  + PA      S TPPP            +    P +  +   PS + P        
Sbjct: 705 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPM--SPSATPPP------R 756

Query: 714 MAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQC-GATLTQVSVEY 772
           +  L  A   Q   +P AS     L     ++P PQ+ P   +   Q   +       + 
Sbjct: 757 VPPLLAAPPLQVPPSPPAS-----LPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQA 811

Query: 773 GYRPGATAVPTPLTNVQILLP--VGEPVTNVRLQPAATWNLE-EKRLTWRLPDVSEAGGS 829
            + P A+   +PL       P  +  P+  V   P A+  L+  +R     PD S +G  
Sbjct: 812 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG-- 869

Query: 830 GRLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDL 864
            RL+ +  P  GP  P        S  +TLSG DL
Sbjct: 870 PRLTLALAP--GPPPPPS-----RSPSSTLSGPDL 897



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 88/353 (24%), Positives = 124/353 (35%), Gaps = 55/353 (15%)

Query: 256 KGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRREREPEPPAAVDFLEPDSG 315
           + +G  +PGPL  +    +A +E + R +  +A +   LS   R              SG
Sbjct: 119 RASGTTRPGPLGQKGLRISA-EETVARGKATEAPKRSALSAGARRDT-----------SG 166

Query: 316 TCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYV----HIKPAPARAPAC 371
             P         R          P    S+      E PRK       H    P+ A   
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226

Query: 372 SPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCAERLQSEEQV 431
            P A     R  + SL     P  +  R S   A G P+ P    +      +     QV
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPAR-SGPSARGTPRAPAHPSQPKPKGLQALRPPQV 285

Query: 432 SKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSPDS 491
           +     PP + A        + +LG  SS SP ++ SP         S + A P P PD+
Sbjct: 286 T-----PPRKDA--------APALGPLSS-SPLATPSP---------SGTKARPVPPPDN 322

Query: 492 WV-PRPGT-PQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPA 549
              P P T P SPP     P       APP P +P  L + P P    A       P+  
Sbjct: 323 AATPLPATLPPSPPLATPLP------LAPPSPSAPPSLQTLPSP---PATPPSQAPPSMT 373

Query: 550 DPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTALERPS 602
            P     + APP       +  P + ++  L    SP  L S  A+T+L  P+
Sbjct: 374 TPP----MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPT 422



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 74/294 (25%), Positives = 100/294 (34%), Gaps = 44/294 (14%)

Query: 352 EEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKP-Q 410
           + P    VH+  AP   P   P  A     A+      P  P  T    +    A  P Q
Sbjct: 651 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP-----PVSPSATPPSQAPPSLAAPPLQ 705

Query: 411 RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPE 470
            P S P +   +       Q    L  PPL+                 +SP    S++P 
Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPP-----------ASPPMSPSATPP 754

Query: 471 NVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASS 530
                 L +P    P PSP + +P     + PP  +APP     +  PPL   P P AS 
Sbjct: 755 PRVPPLLAAPPLQVP-PSPPASLPMSPLAKPPP--QAPP----ALATPPLQALPSPPASF 807

Query: 531 PGPWGLEALAGGDLMP-APADPTAREGLAAP----------------PRRLRSRKVSCPL 573
           PG       A   + P A   P A   LAAP                PRR  +      +
Sbjct: 808 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 867

Query: 574 TRSNGDLSRSLSPSPLGSSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALP 627
           +     L+ +  P P  S + S+ L  P      GH  S   +P  L   D+ P
Sbjct: 868 SGPRLTLALAPGPPPPPSRSPSSTLSGPDL---AGHSSSATSTPEELRGYDSGP 918



 Score = 34.7 bits (78), Expect = 0.40
 Identities = 48/189 (25%), Positives = 65/189 (34%), Gaps = 46/189 (24%)

Query: 364  APARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCAE 423
            AP R P   P+ + +  R T   L L PGP               P  P  +P       
Sbjct: 854  APRRPPTPGPDTSVSGPRLT---LALAPGP---------------PPPPSRSP------- 888

Query: 424  RLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHA 483
                    S  L GP L         T     G+ S P   +++SP    +     P+  
Sbjct: 889  --------SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 940

Query: 484  APGPSPD-SWVPRPGTPQSPPSCRAPPPEARGI----------RAPPLPDSPQPLASSPG 532
            + GP+P  ++   PG P   P     P  A G+           A P P +  P   SPG
Sbjct: 941  SRGPAPPLAFRGAPGAPLPWPPATG-PGSADGLCTIYETEGPESATPAPGALDP-GPSPG 998

Query: 533  PWGLEALAG 541
              G +A AG
Sbjct: 999  TSGGKAAAG 1007



 Score = 34.3 bits (77), Expect = 0.53
 Identities = 57/245 (23%), Positives = 80/245 (32%), Gaps = 61/245 (24%)

Query: 474 DSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPP----------------------E 511
           D+  D     A   +P +  P   TP+ P S R PPP                       
Sbjct: 2   DNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAER 61

Query: 512 ARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSC 571
           A GI    +P+S    A   GP    +       PA   P +  G  APP          
Sbjct: 62  AGGIGGATIPES----APRAGP--TRSAGTSSRNPASRPPASGRGERAPP---------- 105

Query: 572 PLTRSNGDLSRSLSPSPLGSSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATA 631
                    +++ SP P+ S   ++   RP  L Q G  +S     V  G     P  +A
Sbjct: 106 ---------AKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS-AEETVARGKATEAPKRSA 155

Query: 632 FTEYVHAYFRGHSPSC-------LARVTG-ELTMTFPAGIVRVFSGTPPPPVLSFRLVHT 683
            +        G +P          +R  G E+ +  PA      S  P PP    R   +
Sbjct: 156 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP-----SARPRPPTEGPRKSVS 210

Query: 684 TAIEH 688
           +A EH
Sbjct: 211 SASEH 215


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 71/238 (29%), Positives = 93/238 (39%), Gaps = 32/238 (13%)

Query: 398 KRHSSRDAAGKPQ---RPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFD--------- 445
           +RH SR +  K +   + +  P T S   R  S    S +   P L S +          
Sbjct: 222 RRHRSRSSKCKRKEKNKEKKRPHTESPGRR--SHRHSSGSSHSPSLSSHYSDSRSPSRLS 279

Query: 446 --HEDF---TGSSSLGFTSSPSPFSSS---SPENVEDSGLDSPSHAAPGPSPDSWVPRPG 497
             H D    TGS     + SPSP   S   SP+    SG  S +H     S  S   +P 
Sbjct: 280 PKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPS 339

Query: 498 TP----QSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEA-LAGGDLMPAPADPT 552
           +P    +   +  AP P ARG  +P    SP+   SS G  G  A  AG           
Sbjct: 340 SPSPRVRDKAAAAAPTPPARGKESP----SPRSAPSSQGRGGRAAGGAGRRRRRRRRRRR 395

Query: 553 AREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTALERPSFLSQTGHG 610
           +R   +AP RR R R    P   S+  LSR+ S S  GS   +     P   S+ GHG
Sbjct: 396 SRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPG-PGPEPGSERGHG 452



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 63/261 (24%), Positives = 84/261 (32%), Gaps = 35/261 (13%)

Query: 362 KPAPARAPACSPEAAAAQLRATAGSLILPPGPG---GTMKRHSSRDAAGKPQRPRSAPRT 418
           +P PA     S   + A+  + +GS    PGPG   G+ + H       K + PR+ P +
Sbjct: 410 RPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPAS 469

Query: 419 SSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLD 478
           +S                  P   A          S   +  P P S SS  +   S   
Sbjct: 470 TS------------------PSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSR 511

Query: 479 SPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLAS--SPGPWGL 536
           S       PS      +P +       RA   EA   RA     S  P+       P  +
Sbjct: 512 SAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFM 571

Query: 537 EALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAAST 596
           E          P   T+      P  R      S  L+      S S SPSP G S  S 
Sbjct: 572 E----------PRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSP-GHSHGSY 620

Query: 597 ALERPSFLSQTGHGVSRGPSP 617
           +       S+T    SR PSP
Sbjct: 621 SSRSHGTRSRT-RSPSRTPSP 640


>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
          Length = 962

 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 94/377 (24%), Positives = 131/377 (34%), Gaps = 96/377 (25%)

Query: 297 REREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDF---DDEE 353
           +E EP PP   D  +   G  PE + E  T   +  + +  EP R  +  S         
Sbjct: 437 KEAEPTPPVLPDEEKGPPGPAPEPEREAET---EPERGAGTEPERIGTEPSTAPAPSPPA 493

Query: 354 PRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDA-AGKPQRP 412
           P+    H   A +  PA SP  AAA+      S  + PGPG       S DA A  P+RP
Sbjct: 494 PKSCLKHRPAAASEGPAASPPLAAAE------SPPVEPGPG-------SLDAEAAAPERP 540

Query: 413 RS--APRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSS-----------LGFTS 459
           ++  A    + AER   E +  +   G  L  A   + F+ SS            L   S
Sbjct: 541 KAERAEAPPAGAERAAPERKAERG--GAELRGA---KKFSVSSCRARPRPGVSRPLERAS 595

Query: 460 SPSPFSSSSPENVEDSGLDS------PSHAAPGP-----------------------SPD 490
              P + S P    ++ LD       P HA PGP                       SP 
Sbjct: 596 GRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQ 655

Query: 491 SWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPAD 550
                PGT +  P+ + P        AP    +P P+                L      
Sbjct: 656 EAAAAPGTREPCPAAQEP--------APSEDRNPFPV---------------KLRSTSLS 692

Query: 551 PTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTALERPSFLSQTGHG 610
              R+G +   + ++       L RS   L +     PLG++ A      P   S  G G
Sbjct: 693 LKYRDGASQEVKGVKRYSAEVRLERSLTVLPKE-EKCPLGTAPALRGTRAP---SDQGKG 748

Query: 611 VSRGPSPVVLGSQDALP 627
            +R P P  L S+  LP
Sbjct: 749 KARPPEP--LSSKPPLP 763



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 57/223 (25%), Positives = 80/223 (35%), Gaps = 25/223 (11%)

Query: 365 PARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCAER 424
           PA      PE+A   LR    S   P GP         +D    P  P  AP T    E 
Sbjct: 336 PATPELAEPESAPT-LRVEPPSP--PEGPPNPGPDGGKQDGEAPPAGP-CAPATDKAEEV 391

Query: 425 LQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPE-NVEDSGLDSP--- 480
           + + E V+      P  +A    D T   +    +S +P +   PE +V      +P   
Sbjct: 392 VCAPEDVAS-----PFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVL 446

Query: 481 ---SHAAPGPSPD-----SWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDS---PQPLAS 529
                  PGP+P+        P  G    P      P  A    +PP P S    +P A+
Sbjct: 447 PDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPA-PSPPAPKSCLKHRPAAA 505

Query: 530 SPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCP 572
           S GP     LA  +  P    P + +  AA P R ++ +   P
Sbjct: 506 SEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAP 548



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 37/136 (27%), Positives = 52/136 (38%), Gaps = 19/136 (13%)

Query: 465 SSSSPENVEDSGLDSPSHAAPGPSPDSW--VPRPGTPQSPPSCRAPPPEARGIRAPPLPD 522
           SS+   +VE+ G+       PG  P S    P    P+S P+ R  PP        P PD
Sbjct: 315 SSALTASVEEGGV-------PGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPD 367

Query: 523 SPQPLASSP--GPWGLEALAGGDLMPAPAD-----PTA-REGLAAPPRRLRSRKVSCPLT 574
             +    +P  GP         +++ AP D     PTA  EG   PP    +     P  
Sbjct: 368 GGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSA 427

Query: 575 RSNGDLS--RSLSPSP 588
           R   + S  +   P+P
Sbjct: 428 RDGPERSVPKEAEPTP 443



 Score = 30.8 bits (68), Expect = 5.8
 Identities = 57/260 (21%), Positives = 81/260 (31%), Gaps = 35/260 (13%)

Query: 363 PAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKR--HSSRDAAGKPQRPRSAPRTSS 420
           P     P    EAA   L+         PGP    +R    S D A  P  PR +P+ ++
Sbjct: 599 PLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAA 658

Query: 421 --------CAERLQSEEQVSKNLFGPPLES---AFDHEDFTGSSSLGFTSSPSPFSSSSP 469
                   C    +      +N F   L S   +  + D       G     +       
Sbjct: 659 AAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERS 718

Query: 470 ENVEDSGLDSPSHAAPG----PSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQ 525
             V       P   AP      +P         P  P S + P P    +++  LP  P 
Sbjct: 719 LTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPA 778

Query: 526 PLASSPG------------PWGLEALAGGDLMPAPADPTAREGLAAPP-----RRLRSRK 568
           P  + PG               L   A   L PA   P A +G  APP     R+ R   
Sbjct: 779 PPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGA-DGQPAPPWITVTRQKRRGT 837

Query: 569 VSCPLTRSNGDLSRSLSPSP 588
           +  P  + +   +R+L   P
Sbjct: 838 LDQPPNQEDKPGARTLKSEP 857


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 84/360 (23%), Positives = 117/360 (32%), Gaps = 50/360 (13%)

Query: 273  AAALQEAMKRLRGAKAFRLPGLSRREREPEP-----PAAVDFLEPDSGTCPEVDEEGFTV 327
            A+ L E     +G+K    P  +     P P     P+AV  L P   T P  +    T 
Sbjct: 833  ASFLPENSLSFQGSKDS--PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKE----TP 886

Query: 328  RPDVT-----QNSTAEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPAC-SPEAAAAQLR 381
             P V      +   A P+   +         P+K      PAP   PA  SP+ A     
Sbjct: 887  TPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK--ARATPAPKGIPASPSPKGAPTPPA 944

Query: 382  ATAGS-----------------LILPPGPGGTMKRHSSRDA----AGKPQRPRSAPRTSS 420
            AT  S                    PP P G     S + A    A  P  P+  P T S
Sbjct: 945  ATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPS 1004

Query: 421  CAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSP 480
                         +  G P  + F      G+S+    + PSP  S +   +      +P
Sbjct: 1005 PKGAPTPPAVTPPSPKGSPAATPFPK----GASTPPAATPPSPKGSPAATPLPKGAPTTP 1060

Query: 481  SHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEAL- 539
            +   P P      P      +PP+   P P+       P      P A+ P P G  A  
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120

Query: 540  --AGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTA 597
               G    PA   P+ + GLA PP +      +       G L+   +P P G+     A
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA---TPPPKGAPTTPAA 1177



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 56/219 (25%), Positives = 79/219 (36%), Gaps = 20/219 (9%)

Query: 363  PAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCA 422
            P+P  +PA +P    A     A       GP     + +    A  P  P+  P T S  
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100

Query: 423  ER----LQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSS-SSPENVEDS-- 475
                    +       L  PP + A      T  S  G  ++P P  + ++P     S  
Sbjct: 1101 GAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1160

Query: 476  -GLDSP-------SHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDS--PQ 525
             GL +P       + AA  PSP   +  P    +P +  A PP  +G  A P P      
Sbjct: 1161 GGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1220

Query: 526  PLASSPGPWG---LEALAGGDLMPAPADPTAREGLAAPP 561
            P A+ P P G     +  G    PA   P+ + G A PP
Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP 1259



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 67/325 (20%), Positives = 109/325 (33%), Gaps = 41/325 (12%)

Query: 332  TQNSTAEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAP----ACSPEAAAAQLRATAGSL 387
            T++S A  +  S     +  + P    V + P   R P    +  P+     L +    +
Sbjct: 772  TEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPV 831

Query: 388  ILPPGPGGTMKRHSSRDAAGK-----PQRPRSAPRTSSCAE------RLQSEEQVSKNLF 436
                 P  ++    S+D+        P  P+ AP  S+          L  +E  + ++ 
Sbjct: 832  EASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVV 891

Query: 437  -------GPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSP 489
                   GP   +       + +SS    +  +P     P +    G  +P  A P PSP
Sbjct: 892  NLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATP-PSP 950

Query: 490  DSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQ--PLASSPGPWGLEALA---GGDL 544
                  P    +P    A PP  +G  A P P      P A+ P P G  A     G   
Sbjct: 951  KGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPT 1010

Query: 545  MPAPADPTAR---------EGLAAPPRRL----RSRKVSCPLTRSNGDLSRSLSPSPLGS 591
             PA   P+ +         +G + PP       +    + PL +       +  PSP G 
Sbjct: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG 1070

Query: 592  SAASTALERPSFLSQTGHGVSRGPS 616
             A  +    P+  + T      GP+
Sbjct: 1071 PATPSLKGAPTPPAATPPSPKGGPA 1095



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 59/221 (26%), Positives = 79/221 (35%), Gaps = 44/221 (19%)

Query: 363  PAPARAPAC-SPEAAAAQLRATA----GSLILPPGPGG----TMKRHSSRDAAGKPQRPR 413
            P+P   PA  SP+ A     AT     G L  PP  G          S +     P  P+
Sbjct: 1088 PSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP-PK 1146

Query: 414  SAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSS-SSPENV 472
             AP T +      +       L  PP + A      T  S  G  ++PSP  + ++P   
Sbjct: 1147 GAPTTPAA-----TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1201

Query: 473  EDS---GLDSPSH-------AAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPD 522
              S   GL +PS        AA  PSP   +  P    +P +  A PP  +G  A P P 
Sbjct: 1202 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPP- 1260

Query: 523  SPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRR 563
                              G    PA   P+ + GLA PP +
Sbjct: 1261 -----------------KGAPTPPAATPPSLKGGLATPPHK 1284



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 61/266 (22%), Positives = 92/266 (34%), Gaps = 37/266 (13%)

Query: 363  PAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCA 422
            P+P  +P   P   A    A     + PP P GT    ++  ++      +  P T S  
Sbjct: 1318 PSPKGSPGTPPPKGAPTPPA-----VTPPSPKGTPTLPATTPSS------KGGPTTPSSK 1366

Query: 423  ERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPEN----VEDSGLD 478
            E          +  GP +            S  G  +SP+    S  +     V   G  
Sbjct: 1367 EGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAA 1426

Query: 479  SPSHAAPGP----------SPDSWVPR--PGTPQSPPSCRAPPPEARGIRAPPLP----- 521
            +PS     P          +P +  P+  P TP S      P       + PP P     
Sbjct: 1427 TPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVAT 1486

Query: 522  -DSPQPLASSPGPWG---LEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSN 577
              SP+   ++P P G   L A+        PA P++R    AP   L S+K    L    
Sbjct: 1487 SSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKE 1546

Query: 578  GDLSRSLS-PSPLGSSAASTALERPS 602
              +  +++ PSP  + A  T  E P+
Sbjct: 1547 ALIPPAMTVPSPKKTPAIPTPKEAPA 1572



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 63/259 (24%), Positives = 93/259 (35%), Gaps = 53/259 (20%)

Query: 372  SPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDA----AGKPQRPRSAPRTSSCAERLQS 427
            SP+ A     AT      PP P G +   S + A    A  P  P+  P T         
Sbjct: 1213 SPKGAPTTPAAT------PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP-----PK 1261

Query: 428  EEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGP 487
                      P L+         G+ +    + PSP     P      G  +P  A P P
Sbjct: 1262 GAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP--KGGPATSPPKGAPTPPAATP-P 1318

Query: 488  SPDSWVPRPGTPQSPPSCRAPPPEA--------------------RGIRAPPLPDSPQPL 527
            SP       G+P +PP   AP P A                     G   P   + P P 
Sbjct: 1319 SPK------GSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPP 1372

Query: 528  ASSPGPWGLEALA-----GGDLMPAP-ADPTAREGLAAPPRRLRSRKVS--CPLTRSNGD 579
            A++P   G  A+       G  +P+P  DPT+   +   P++  +  V+     T S GD
Sbjct: 1373 AATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432

Query: 580  LS-RSLSPSPLGSSAASTA 597
            L+  +++P  L  + A++A
Sbjct: 1433 LTPPAVTPVSLKKAPATSA 1451



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 62/251 (24%), Positives = 89/251 (35%), Gaps = 27/251 (10%)

Query: 352  EEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQR 411
            E P    V    +P +APA      A  L A     ++P  P       SSR       R
Sbjct: 1477 EPPAPKQVATSSSPKKAPATPAPMGAPTLPA-----VIPSSPKEVPATPSSR-------R 1524

Query: 412  PRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPEN 471
               AP  +  +++  +     + L  P +      +     +     ++PS   +SSP  
Sbjct: 1525 DPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA 1584

Query: 472  VEDS---GLDSPSH-----AAPGPSP-DSWVPRPGTPQSPPSCRAPPPEARGIRAPP--- 519
            V  S   G  SP       A   PSP ++  P   TP SP    A P       +PP   
Sbjct: 1585 VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTP 1644

Query: 520  --LPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSN 577
              L DSP   AS     G         +PA   PTA + +   P    +  ++ P TR  
Sbjct: 1645 SSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAP-TRKG 1703

Query: 578  GDLSRSLSPSP 588
                +S + SP
Sbjct: 1704 PQTKKSSATSP 1714



 Score = 34.3 bits (77), Expect = 0.53
 Identities = 120/597 (20%), Positives = 202/597 (33%), Gaps = 124/597 (20%)

Query: 299  REPEPPAAVDFLEPDSGTCPEVDE---------EGFTVRPDV-TQNSTAEPSRFSSSDSD 348
            +EP    A     P S   P+ ++           F  + D+ T  ++ E + FS + + 
Sbjct: 491  KEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAG 550

Query: 349  FDDEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAA-- 406
               ++       ++ AP  +P+          ++T+ S  +P  P  T+ + S  +    
Sbjct: 551  LTTKKDPTVLPLVQAAPKNSPS---------FQSTSSSPEIPLSPEATLAKKSLGEPLPI 601

Query: 407  GKPQRPRSAPR-TSSCAERLQSEEQVSKNLFGPPLES--------AFDHEDF-------- 449
            GKP    ++P   +S A  ++++     +  GP L+S        AF  E          
Sbjct: 602  GKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPT 661

Query: 450  TGSSSLGFTSSPSPFS----SSSPEN--VEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPP 503
            T   +  +T++ SPF     S +P+N  V++  L +              P P    +P 
Sbjct: 662  TAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPL 721

Query: 504  SCRAPPPEA-RGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPR 562
            +     PE  + + +P LP    P  + PG   ++ ++           +A   +A+ P+
Sbjct: 722  ATLVLAPEIPKSVPSPSLP----PAGTPPGTKKVDGIS---------HTSALAPVASSPK 768

Query: 563  RLRSRKVSCPLTRSNGDLSRSL--SPSPLGSSAASTALERPSFLSQTGHGVSRGPSPVVL 620
               +       T S+      L  SPSPLG S +      P     T  G +   +P+  
Sbjct: 769  ECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPP-----TKKGSAGPDTPIGN 823

Query: 621  GSQDALPIATAFTEYVHAYFRGHSPSCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRL 680
             S    P+  +F       F+G   S             PA      S TPP P  +   
Sbjct: 824  LSSPVSPVEASFLPENSLSFQGSKDS-------------PA---TTHSPTPPSPKGA--- 864

Query: 681  VHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEALQRQAEQNPTASYYNVVLLR 740
                               PS   P +           + +    ++ PT S  N+   +
Sbjct: 865  -----------------PTPSAVTPLSP----------KGVTLPPKETPTPSVVNLPFPK 897

Query: 741  YQFSRPGPQSVP-LQLSAHWQCGATLTQVSVEYGYRPGATAVPTPLTNVQILLPVGEPVT 799
               + P P+  P L +++     A  T         P     PTP        P G P T
Sbjct: 898  EGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPS-PKGGPAT 956

Query: 800  NVRLQPAATWNLEEKRLTWRLPDVSEAGGSGR------LSASWEPLSGPSTPSPVAA 850
                 P+  W       T   P    A  S +       +    P  GP+TPSP  A
Sbjct: 957  -----PSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGA 1008



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 43/177 (24%), Positives = 67/177 (37%), Gaps = 14/177 (7%)

Query: 361  IKPAPARAPACSPEAAAAQLRATA--GSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRT 418
            + P+  +    SP +   ++ AT    S  LP   G T  +      A     P S P  
Sbjct: 1642 VTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPA-----PESTPII 1696

Query: 419  SSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLD 478
            ++   +    ++ S     PP+    D     GS     T +P+P      ++ + +   
Sbjct: 1697 TAPTRKGPQTKKSSAT--SPPI--CPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGK 1752

Query: 479  SPSHAAPGP--SPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGP 533
              SH+  GP   P+S    P T  +      P PE+  + A P P    PLA SP P
Sbjct: 1753 DASHSPKGPLAPPESKASTPLTAAAFEKV-LPKPESASVSAAPSPPVSLPLAPSPVP 1808


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 46/124 (37%), Positives = 53/124 (42%), Gaps = 21/124 (16%)

Query: 445 DHEDF-------TGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSPDSWVPRPG 497
           DH+D         G +S    + P P +S  P     SGL S S A P P   +  P P 
Sbjct: 623 DHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPP 682

Query: 498 TPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGL 557
            P  PP    PPP + G   PP P  P PL +SP P       GG   P PA P    GL
Sbjct: 683 PPPPPPP--LPPPSSAG---PPPPPPPPPLPNSPAP----PNPGG---PPPAPPP--PGL 728

Query: 558 AAPP 561
           A PP
Sbjct: 729 APPP 732



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 103/452 (22%), Positives = 152/452 (33%), Gaps = 104/452 (23%)

Query: 132 QLLPKSRENYLN--RCMDQERLRRESTSQ-KEMDKAETKTKKAAESLRRSVEKYNSARAD 188
           ++ PKS E  L   + +     R+ +T+   E++  + K +   ESLR   E+ NS  AD
Sbjct: 392 EVKPKSPETALEAFKALFIRPPRKGTTADTSELEALKRKMRHEKESLRAVFERSNSKPAD 451

Query: 189 FEQKMLDSALRFQAMEETHLRHMKALLGSYAH-SVEDTHVQIG-------------QVHE 234
                 DS     ++ E   R    L   +     +DT  ++G              +  
Sbjct: 452 GPS---DSKSPDHSLTEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTEAEYQAAILHLKR 508

Query: 235 EFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGL 294
           E K+ IEN+  +  LR F   +G            A   A L+E ++ L+     R  G 
Sbjct: 509 EHKEEIENLQAQFELRAF-HIRGE----------HAMITARLEETIENLKHELEHRWRG- 556

Query: 295 SRREREPEPPAAVDFLEPDS--GTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDE 352
              ER+    +  D   P +    C + D E F ++P  +++ T   ++           
Sbjct: 557 GCEERKDVCISTDDDCPPKTFRNVCVQTDRETF-LKPCESESKTTRSNQLV--------- 606

Query: 353 EPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRP 412
            P+K  ++I      +P    +   A L+   G               +S      P  P
Sbjct: 607 -PKK--LNISSLSQLSPPNDHKDIHAALQPMEGM--------------ASNQQKALPPPP 649

Query: 413 RSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSP--- 469
            S P                     PPL S        G  SL       P S+  P   
Sbjct: 650 ASIPPP-------------------PPLPS--------GLGSLSPAPPMPPVSAGPPLPP 682

Query: 470 ENVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLAS 529
                  L  PS A P P P    P P +P +PP+   PPP      APP    P  LA 
Sbjct: 683 PPPPPPPLPPPSSAGPPPPPPP-PPLPNSP-APPNPGGPPP------APP----PPGLAP 730

Query: 530 SPGPWGLEALAGGDLMPAPADPTAREGLAAPP 561
            P P GL    G      P  P         P
Sbjct: 731 PPPP-GLFFGLGSSSSQCPRKPAIEPSCPMKP 761


>gi|239752265 PREDICTED: hypothetical protein XP_002348186 [Homo
           sapiens]
          Length = 225

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 50/155 (32%), Positives = 64/155 (41%), Gaps = 11/155 (7%)

Query: 466 SSSPENVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPP-LPDSP 524
           S SP++V        S   P  SPDS VP PG   SP S   PP     +  PP  PDS 
Sbjct: 52  SRSPDSVVPPPGSPDSVVLPPRSPDSVVPPPG---SPDSVVLPPRSPDSVVPPPRSPDSV 108

Query: 525 QPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSL 584
            P   SP    L   +   ++P P  P   + +  PP   RS     P  RS     R+ 
Sbjct: 109 VPPPGSPDSVVLPPRSPDSVVPPPGSP---DSVVLPP---RSPDSVVPPARSPDSGGRAG 162

Query: 585 SPSPLGSSAASTALERPSFLSQTGH-GVSRGPSPV 618
           SP  L   AA+ A   P +  + G   ++R P  V
Sbjct: 163 SPRSLAPPAAARAEGAPGWAGRWGRVPLARSPPQV 197



 Score = 38.9 bits (89), Expect = 0.021
 Identities = 63/226 (27%), Positives = 82/226 (36%), Gaps = 32/226 (14%)

Query: 369 PACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQR-PRSAPRTSSCAERLQS 427
           P+ SP++     R+   S++LPPG         S D+   P R P S        + +  
Sbjct: 21  PSRSPDSVVLPSRSP-DSVVLPPG---------SPDSVVLPSRSPDSVVPPPGSPDSVVL 70

Query: 428 EEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSP----SHA 483
             +   ++  PP           GS         SP S   P    DS +  P    S  
Sbjct: 71  PPRSPDSVVPPP-----------GSPDSVVLPPRSPDSVVPPPRSPDSVVPPPGSPDSVV 119

Query: 484 APGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGD 543
            P  SPDS VP PG   SP S   PP     +  P         A SP      A A  +
Sbjct: 120 LPPRSPDSVVPPPG---SPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRSLAPPAAARAE 176

Query: 544 LMPAPADPTAREGLAAPPRRLRSR--KVSCPLTRSNGDLSRSLSPS 587
             P  A    R  LA  P ++ SR   +S PL+ S   L   L PS
Sbjct: 177 GAPGWAGRWGRVPLARSPPQVPSRPPSLSQPLS-SRVSLYELLFPS 221


>gi|51702222 SPT2, Suppressor of Ty, domain containing 1 [Homo
           sapiens]
          Length = 685

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 122/527 (23%), Positives = 190/527 (36%), Gaps = 96/527 (18%)

Query: 126 VLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMD-KAETKTKKAAESLRRSVEKYNS 184
           V S   Q   K +E  L R   +E+ R+E   +K ++ K + K +  A+  + +   YN 
Sbjct: 39  VQSAAVQAFLKRKEEELRRKALEEKRRKEELVKKRIELKHDKKARAMAKRTKDNFHGYNG 98

Query: 185 ARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNIENVS 244
              + + K      + QA E              +H+ + T         E++   EN  
Sbjct: 99  IPIEEKSK------KRQATE--------------SHTSQGTD-------REYEMEEEN-- 129

Query: 245 VEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRREREPEPP 304
            E L    AES+    E+  P   E+     L+ A   +      RL    +++ EP   
Sbjct: 130 -EFLEYNHAESEQEYEEEQEPPKVESKPKVPLKSAPPPMNFTDLLRLA--EKKQFEPVEI 186

Query: 305 AAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVHIKPA 364
             V   E    T  E+ E  F  R                          +K     K  
Sbjct: 187 KVVKKSEERPMTAEELREREFLERK----------------------HRRKKLETDGKLP 224

Query: 365 PARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCAER 424
           P  +     +  +   + + GS    P   G    H+ + +       +    +SS +  
Sbjct: 225 PTVSKKAPSQKESVGTKLSKGSGDRHPSSKGMPLPHAEKKSRPSMANEKHLALSSSKSMP 284

Query: 425 LQSEEQVSKNLFGPPLESAFDHEDFTGSSSL-GFTSSPS-PFSSSSP------ENVEDSG 476
            +  +  S N   P L    D   F G+      TSSPS P +S+S       E+     
Sbjct: 285 GERIKAGSGNSSQPSLREGHDKPVFNGAGKPHSSTSSPSVPKTSASRTQKSAVEHKAKKS 344

Query: 477 LDSPSHAAPGP--SPDSWVPRPGTPQ-SPPSCRAPPPEARGIRAPPLPDSPQPL----AS 529
           L  PSH+ PGP  +P +    PG  Q    S  AP   + G+  P +   P P     +S
Sbjct: 345 LSHPSHSRPGPMVTPHNKAKSPGVRQPGSSSSSAPGQPSTGVARPTVSSGPVPRRQNGSS 404

Query: 530 SPGPWGLEALAGGDLMPAPADPTAR--EGLAAPPRRLRSRKVSCPLTRSNG---DLSRSL 584
           S GP    +++G       ++P+ R   G   P +         P + S G    +S S+
Sbjct: 405 SSGP--ERSISGSKKPTNDSNPSRRTVSGTCGPGQ---------PASSSGGPGRPISGSV 453

Query: 585 SPS-PLGSS-------AASTALERP-SFLSQTGHGVSRGPSPVVLGS 622
           S + PLGSS       ++   L RP S L   G  VS GP   + GS
Sbjct: 454 SSARPLGSSRGPGRPVSSPHELRRPVSGLGPPGRSVS-GPGRSISGS 499


>gi|157743252 pecanex-like 3 [Homo sapiens]
          Length = 2034

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 55/170 (32%), Positives = 66/170 (38%), Gaps = 38/170 (22%)

Query: 445  DHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPS 504
            D  D +G   L   S+  P +  +PEN   +G D P    PG  P S +   G  + PP 
Sbjct: 1836 DDSDCSGGGGLTSLSNNPPVAHPTPENTAGNG-DQPLPPGPGWGPRSSLSGSGDGRPPPL 1894

Query: 505  CRAPPPEARGIRAPPLPDSPQP-------------LASSPGP---W---GLEALAGGDLM 545
             + PPP   G    P P SP P             L SS GP   W   G + L G D  
Sbjct: 1895 LQWPPPRLPG----PPPASPIPTEGPRTSRPPGPGLLSSEGPSGKWSLGGRKGLGGSDGE 1950

Query: 546  PAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAAS 595
            PA   P              + K   PL  S   LS SLS SP  S+ AS
Sbjct: 1951 PASGSPKG-----------GTPKSQAPLDLS---LSLSLSLSPDVSTEAS 1986



 Score = 30.4 bits (67), Expect = 7.6
 Identities = 69/288 (23%), Positives = 99/288 (34%), Gaps = 35/288 (12%)

Query: 363 PAPARAPACSPEAAAAQLRATAGSLI----LPPGPGGTMKRHSSRDAAGKPQRPRSAPRT 418
           P+ A   +  P   A      +GS +    + P   G++ +  S+      Q  R+  RT
Sbjct: 207 PSLASTDSSEPSPLAGDGAPWSGSSMADTPMSPLLKGSLSQELSKSFLTLTQPDRALVRT 266

Query: 419 SSCAERLQSE---EQVSKNLFGPPL-------ESAFDHEDFTGSSSLGFTSSPSPFSSSS 468
           SS  E+ +     + + +   G P        +S F   D    SS     + S    S 
Sbjct: 267 SSRREQRRGAGGYQPLDRRGSGEPTPQKAGSSDSCFSGTDRETLSSFKSEKTNSTHLDSP 326

Query: 469 PENV--EDSGLDSPSHAAPGPSPDSWVPRPGTPQS---------PPSCRAP----PPEAR 513
           P     E S  D PS A    SPD+ VP   T +S         PP    P     P+  
Sbjct: 327 PGGPAPEGSDTDPPSEAELPASPDAGVPSDDTLRSFDTVIGAGTPPGLAEPLLVVRPKDL 386

Query: 514 GIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRS-RKVSCP 572
            +  P     P    S PG      L  G       D T+     +P   LRS R+ S  
Sbjct: 387 ALLRPSKRQPPLRRHSPPGRAPRRPLLEGGGFFEDED-TSEGSELSPASSLRSQRRYSTD 445

Query: 573 LTRSNG----DLSRSLSPSPLGSSAASTALERPSFLSQTGHGVSRGPS 616
            + S      + SR  +  P    A   A E  +   +  +G  R PS
Sbjct: 446 SSSSTSCYSPESSRGAAGGPRKRRAPHGAEEGTAVPPKRPYGTQRTPS 493


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 85/341 (24%), Positives = 115/341 (33%), Gaps = 67/341 (19%)

Query: 383 TAGSLILPPG---PGGTMK------RHSSRDAAGKPQRPRSAPRTSSCAERLQSEEQVSK 433
           + G+ + P G    GG +K      +  S + AGKP      P + + A R         
Sbjct: 76  SGGAALQPKGGLFQGGVLKLRPVGAKDGSENLAGKPAL--QIPSSRAAAPR--------- 124

Query: 434 NLFGPPLESAFDH-EDFTGSS-----SLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGP 487
               PP+ +A    +D T SS      L     PS    S P     +G+   S A P P
Sbjct: 125 ----PPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPP 180

Query: 488 SPDSWVPRPGTPQSPPSCRAPP-------PEARGIRAPP---LPDSPQPLASSPGPWGLE 537
            P      P TP    S +AP        P   G R  P    P +P P+   P P  + 
Sbjct: 181 PPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSPVNIR 240

Query: 538 ALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCP--------LTRSNGDLSRSLSPSPL 589
               G  + AP  P  R+    P         S P        L R      R L+P P 
Sbjct: 241 TGPSGQSL-APPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPP 299

Query: 590 GSSAASTALER--PSFLSQTGHGVSRGPSPVVL--GSQDALPIATAFTEYVHAYFRGHSP 645
            S++ S    R  P        G +  P P V+  G++DA P    +         G  P
Sbjct: 300 TSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYR------MHGSEP 353

Query: 646 SCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAI 686
               +         P    R  +G PPPP    R  H  +I
Sbjct: 354 PSRGKP--------PPPPSRTPAGPPPPPPPPLRNGHRDSI 386


>gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo
           sapiens]
          Length = 1235

 Score = 50.1 bits (118), Expect = 9e-06
 Identities = 55/203 (27%), Positives = 75/203 (36%), Gaps = 39/203 (19%)

Query: 487 PSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMP 546
           P P    P P  PQ+ P  RAP P+   ++    P  P PL++ P     EA     L P
Sbjct: 298 PCPQVAQPIP-QPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEA----QLQP 352

Query: 547 APADPTAREGLAAPPRRL------------RSRKVSCPLTRSNGDLSRSLSPSPLGSSAA 594
           AP     R      P +L             ++ +S PL+  N   S SLS + L SS +
Sbjct: 353 APQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYN---SSSLSLNSLSSSRS 409

Query: 595 STALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLARVTGE 654
           ST  +         H  S  P P+ L +   L    +FT  +      H P+  A  T  
Sbjct: 410 STPAKTQPAPPHISHHPSASPFPLSLPNHSPL---HSFTPTLQPPAHSHHPNMFAPPT-- 464

Query: 655 LTMTFPAGIVRVFSGTPPPPVLS 677
                           PPPP L+
Sbjct: 465 --------------ALPPPPPLT 473


>gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo
           sapiens]
          Length = 1259

 Score = 50.1 bits (118), Expect = 9e-06
 Identities = 55/203 (27%), Positives = 75/203 (36%), Gaps = 39/203 (19%)

Query: 487 PSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMP 546
           P P    P P  PQ+ P  RAP P+   ++    P  P PL++ P     EA     L P
Sbjct: 298 PCPQVAQPIP-QPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEA----QLQP 352

Query: 547 APADPTAREGLAAPPRRL------------RSRKVSCPLTRSNGDLSRSLSPSPLGSSAA 594
           AP     R      P +L             ++ +S PL+  N   S SLS + L SS +
Sbjct: 353 APQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYN---SSSLSLNSLSSSRS 409

Query: 595 STALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLARVTGE 654
           ST  +         H  S  P P+ L +   L    +FT  +      H P+  A  T  
Sbjct: 410 STPAKTQPAPPHISHHPSASPFPLSLPNHSPL---HSFTPTLQPPAHSHHPNMFAPPT-- 464

Query: 655 LTMTFPAGIVRVFSGTPPPPVLS 677
                           PPPP L+
Sbjct: 465 --------------ALPPPPPLT 473


>gi|157074225 nuclear pore complex interacting protein-like 3 [Homo
           sapiens]
          Length = 678

 Score = 50.1 bits (118), Expect = 9e-06
 Identities = 69/256 (26%), Positives = 94/256 (36%), Gaps = 49/256 (19%)

Query: 361 IKPAPARAPACSPEAAAAQLRATAGSLI--LPPGPGGTMKRHSSRDAAGKPQR--PRSAP 416
           + P P  A   +P +A   L+  A  L+  LPP     +K  S R     P    P +  
Sbjct: 347 LTPLPPSALPSAPPSADDNLKTRAECLLHPLPPSADDNLKTPSERQLTPLPPSAPPSADD 406

Query: 417 RTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSG 476
              + AERL+          GP   SA D+        L      +P   S+P + +D+ 
Sbjct: 407 NIKTPAERLR----------GPLPPSADDNLKTPSERQL------TPLPPSAPPSADDN- 449

Query: 477 LDSPSHAAPGPSPDSWVPRPGTPQS------PPSCRAPPPEARGIRAP------PLPDSP 524
           + +P+    GP P S      TP        PPS  APP     I+ P      PLP S 
Sbjct: 450 IKTPAERLRGPLPPSADDNLKTPSERQLTPLPPS--APPSADDNIKTPAERLRGPLPPSA 507

Query: 525 QPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSL 584
                +P    L  L      P  A P+A + +  P  RLR      PL  S  D   +L
Sbjct: 508 DDNLKTPSERQLTPL------PPSAPPSADDNIKTPAERLRG-----PLPPSADD---NL 553

Query: 585 SPSPLGSSAASTALER 600
              PL +  A     R
Sbjct: 554 KTPPLATQEAEAEKPR 569



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 60/246 (24%), Positives = 88/246 (35%), Gaps = 39/246 (15%)

Query: 360 HIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTS 419
           ++K  P       P +A   L+     L+ P  P       +  +    P  P + P   
Sbjct: 300 NLKTPPECVLTPLPPSADDNLKTPPECLLTPLPPSADDNLKTPPECLLTPLPPSALPSAP 359

Query: 420 SCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDS 479
             A+   + +  ++ L  P   SA D+        L      +P   S+P + +D+ + +
Sbjct: 360 PSAD--DNLKTRAECLLHPLPPSADDNLKTPSERQL------TPLPPSAPPSADDN-IKT 410

Query: 480 PSHAAPGPSPDSWVPRPGTPQS------PPSCRAPPPEARGIRAP------PLPDSPQPL 527
           P+    GP P S      TP        PPS  APP     I+ P      PLP S    
Sbjct: 411 PAERLRGPLPPSADDNLKTPSERQLTPLPPS--APPSADDNIKTPAERLRGPLPPSADDN 468

Query: 528 ASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGD-----LSR 582
             +P    L  L      P  A P+A + +  P  RLR      PL  S  D       R
Sbjct: 469 LKTPSERQLTPL------PPSAPPSADDNIKTPAERLRG-----PLPPSADDNLKTPSER 517

Query: 583 SLSPSP 588
            L+P P
Sbjct: 518 QLTPLP 523


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 73/314 (23%), Positives = 106/314 (33%), Gaps = 66/314 (21%)

Query: 326 TVRPDVTQNSTAEPSRFSSSDSDFDDEEPRK------FYVHIKPAPARAPACSPEAAAAQ 379
           T + D+ +  + +PS  S S        P K       +   +P PA+ PA  P      
Sbjct: 283 TKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPA-QPSGLTKP 341

Query: 380 LRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCAERLQSEEQVSKNLFGPP 439
           L    G++  P  P GT K         +P  P   P   + +E+  SE+   K L  PP
Sbjct: 342 LAQQPGTVKPPVQPPGTTK------PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395

Query: 440 LESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAA---------PGPS-- 488
                     T +   G    P+    +     +  GL SP+ A          PGP   
Sbjct: 396 GVGK------TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449

Query: 489 -------------------PDSWVPRPGTPQ-SPPSCRAPPPEARGIRAPPL-------- 520
                              P S +P P  P    P    PPP+  G   PP         
Sbjct: 450 PAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP 509

Query: 521 -PDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGD 579
            P  P P   SP   G  +       P  A P+A++   A P   +S K   P++++   
Sbjct: 510 PPQQPGPAKPSPQQPG--STKPPSQQPGSAKPSAQQPSPAKPSAQQSTK---PVSQTGS- 563

Query: 580 LSRSLSPSPLGSSA 593
             + L P  +  SA
Sbjct: 564 -GKPLQPPTVSPSA 576



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 61/241 (25%), Positives = 84/241 (34%), Gaps = 39/241 (16%)

Query: 295  SRREREPEPPAAVDFLEPDSGTCPEVD-----EEGFTVRPDVTQNSTAEPSRFSSS---- 345
            S+ E +  PP   D  +P     P  +     +     RP       + P   S S    
Sbjct: 785  SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK 844

Query: 346  --DSDFDDEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSR 403
              D     EEP+K    + P P   P           R TAG  +  P      +  S R
Sbjct: 845  QVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRR 904

Query: 404  ---DAAGKPQRPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSS 460
               +       P+S P T         +E V+  LFG      F    F+ +S+L  T+ 
Sbjct: 905  FSLNLGSITDAPKSQPTTP--------QETVTGKLFG------FGASIFSQASNLISTAG 950

Query: 461  -PSPFSSSSPENVEDSGLDSPSHAAPGPS--PDSWVPRPGTPQSPPSCRAPPPEARGIRA 517
             P P S S P         +P   AP PS  P S  P   T Q+PP+     P  +  +A
Sbjct: 951  QPGPHSQSGP--------GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKA 1002

Query: 518  P 518
            P
Sbjct: 1003 P 1003



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 72/270 (26%), Positives = 100/270 (37%), Gaps = 56/270 (20%)

Query: 362 KPAPARAPACSPE---AAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRT 418
           KPAP + P+   E   A  A  +     ++ P     T    SS  A  KP  P S  ++
Sbjct: 731 KPAPPKEPSVPSEQDKAPVADDKPKQPKMVKP-----TTDLVSSSSATTKPDIPSSKVQS 785

Query: 419 SSCAERLQSEEQVSKNLFGPPL--ESAFDHEDFTGSSSLGFTSSPSPFSSSS-PENVEDS 475
                  Q+EE+ +     PPL  +SA   + F  +         SPF S + P    DS
Sbjct: 786 -------QAEEKTT-----PPLKTDSAKPSQSFPPTGE-----KVSPFDSKAIPRPASDS 828

Query: 476 GLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWG 535
            + S     PGPS +S     G  Q  P  +   P+    +  P PD+      SP P G
Sbjct: 829 KIISH----PGPSSES----KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPG 880

Query: 536 LEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSP------- 588
               A G  +P P          +P  + +SR+ S  L  S  D  +S   +P       
Sbjct: 881 PRPTA-GQTVPTPQQ--------SPKPQEQSRRFSLNL-GSITDAPKSQPTTPQETVTGK 930

Query: 589 ---LGSSAASTALERPSFLSQTGHGVSRGP 615
               G+S  S A    S   Q G     GP
Sbjct: 931 LFGFGASIFSQASNLISTAGQPGPHSQSGP 960



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 35/118 (29%), Positives = 44/118 (37%), Gaps = 16/118 (13%)

Query: 422  AERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPS 481
            AER +S   +S+ +F  P  S          S+  FTS  + F    P +   SG  S S
Sbjct: 2328 AERTKSS--LSETVFDHPPSSVIALPMKEQLSTTYFTSGET-FGQEKPASQLPSGSPSVS 2384

Query: 482  HAAPGPSPD------SWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGP 533
                 P P           +P  P  PP    PPP       PP P  P P  +SP P
Sbjct: 2385 SLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPP-------PPPPPPPLPPPTSPKP 2435



 Score = 30.8 bits (68), Expect = 5.8
 Identities = 35/133 (26%), Positives = 46/133 (34%), Gaps = 28/133 (21%)

Query: 406  AGKPQRPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFS 465
            A + ++   A RT S       +   S ++   P++       FT   + G     S   
Sbjct: 2319 AYRDKKELEAERTKSSLSETVFDHPPS-SVIALPMKEQLSTTYFTSGETFGQEKPASQLP 2377

Query: 466  SSSPEN----------VEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGI 515
            S SP               S LD  +   P P P    P P  P  PP    PPP     
Sbjct: 2378 SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP----PPPPPPPPPP----PPP----- 2424

Query: 516  RAPPL--PDSPQP 526
              PPL  P SP+P
Sbjct: 2425 --PPLPPPTSPKP 2435


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 73/314 (23%), Positives = 106/314 (33%), Gaps = 66/314 (21%)

Query: 326 TVRPDVTQNSTAEPSRFSSSDSDFDDEEPRK------FYVHIKPAPARAPACSPEAAAAQ 379
           T + D+ +  + +PS  S S        P K       +   +P PA+ PA  P      
Sbjct: 283 TKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPA-QPSGLTKP 341

Query: 380 LRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCAERLQSEEQVSKNLFGPP 439
           L    G++  P  P GT K         +P  P   P   + +E+  SE+   K L  PP
Sbjct: 342 LAQQPGTVKPPVQPPGTTK------PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395

Query: 440 LESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAA---------PGPS-- 488
                     T +   G    P+    +     +  GL SP+ A          PGP   
Sbjct: 396 GVGK------TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449

Query: 489 -------------------PDSWVPRPGTPQ-SPPSCRAPPPEARGIRAPPL-------- 520
                              P S +P P  P    P    PPP+  G   PP         
Sbjct: 450 PAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP 509

Query: 521 -PDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGD 579
            P  P P   SP   G  +       P  A P+A++   A P   +S K   P++++   
Sbjct: 510 PPQQPGPAKPSPQQPG--STKPPSQQPGSAKPSAQQPSPAKPSAQQSTK---PVSQTGS- 563

Query: 580 LSRSLSPSPLGSSA 593
             + L P  +  SA
Sbjct: 564 -GKPLQPPTVSPSA 576



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 61/241 (25%), Positives = 84/241 (34%), Gaps = 39/241 (16%)

Query: 295  SRREREPEPPAAVDFLEPDSGTCPEVD-----EEGFTVRPDVTQNSTAEPSRFSSS---- 345
            S+ E +  PP   D  +P     P  +     +     RP       + P   S S    
Sbjct: 785  SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK 844

Query: 346  --DSDFDDEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSR 403
              D     EEP+K    + P P   P           R TAG  +  P      +  S R
Sbjct: 845  QVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRR 904

Query: 404  ---DAAGKPQRPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSS 460
               +       P+S P T         +E V+  LFG      F    F+ +S+L  T+ 
Sbjct: 905  FSLNLGSITDAPKSQPTTP--------QETVTGKLFG------FGASIFSQASNLISTAG 950

Query: 461  -PSPFSSSSPENVEDSGLDSPSHAAPGPS--PDSWVPRPGTPQSPPSCRAPPPEARGIRA 517
             P P S S P         +P   AP PS  P S  P   T Q+PP+     P  +  +A
Sbjct: 951  QPGPHSQSGP--------GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKA 1002

Query: 518  P 518
            P
Sbjct: 1003 P 1003



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 72/270 (26%), Positives = 100/270 (37%), Gaps = 56/270 (20%)

Query: 362 KPAPARAPACSPE---AAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRT 418
           KPAP + P+   E   A  A  +     ++ P     T    SS  A  KP  P S  ++
Sbjct: 731 KPAPPKEPSVPSEQDKAPVADDKPKQPKMVKP-----TTDLVSSSSATTKPDIPSSKVQS 785

Query: 419 SSCAERLQSEEQVSKNLFGPPL--ESAFDHEDFTGSSSLGFTSSPSPFSSSS-PENVEDS 475
                  Q+EE+ +     PPL  +SA   + F  +         SPF S + P    DS
Sbjct: 786 -------QAEEKTT-----PPLKTDSAKPSQSFPPTGE-----KVSPFDSKAIPRPASDS 828

Query: 476 GLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWG 535
            + S     PGPS +S     G  Q  P  +   P+    +  P PD+      SP P G
Sbjct: 829 KIISH----PGPSSES----KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPG 880

Query: 536 LEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSP------- 588
               A G  +P P          +P  + +SR+ S  L  S  D  +S   +P       
Sbjct: 881 PRPTA-GQTVPTPQQ--------SPKPQEQSRRFSLNL-GSITDAPKSQPTTPQETVTGK 930

Query: 589 ---LGSSAASTALERPSFLSQTGHGVSRGP 615
               G+S  S A    S   Q G     GP
Sbjct: 931 LFGFGASIFSQASNLISTAGQPGPHSQSGP 960



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 35/118 (29%), Positives = 44/118 (37%), Gaps = 16/118 (13%)

Query: 422  AERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPS 481
            AER +S   +S+ +F  P  S          S+  FTS  + F    P +   SG  S S
Sbjct: 2328 AERTKSS--LSETVFDHPPSSVIALPMKEQLSTTYFTSGET-FGQEKPASQLPSGSPSVS 2384

Query: 482  HAAPGPSPD------SWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGP 533
                 P P           +P  P  PP    PPP       PP P  P P  +SP P
Sbjct: 2385 SLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPP-------PPPPPPPLPPPTSPKP 2435



 Score = 30.8 bits (68), Expect = 5.8
 Identities = 35/133 (26%), Positives = 46/133 (34%), Gaps = 28/133 (21%)

Query: 406  AGKPQRPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFS 465
            A + ++   A RT S       +   S ++   P++       FT   + G     S   
Sbjct: 2319 AYRDKKELEAERTKSSLSETVFDHPPS-SVIALPMKEQLSTTYFTSGETFGQEKPASQLP 2377

Query: 466  SSSPEN----------VEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGI 515
            S SP               S LD  +   P P P    P P  P  PP    PPP     
Sbjct: 2378 SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP----PPPPPPPPPP----PPP----- 2424

Query: 516  RAPPL--PDSPQP 526
              PPL  P SP+P
Sbjct: 2425 --PPLPPPTSPKP 2435


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 54/168 (32%), Positives = 69/168 (41%), Gaps = 34/168 (20%)

Query: 405 AAGKPQRPRSAPR---TSSCAERLQSEEQVSKNLF----GPPLESAFDHEDFT-GSSSLG 456
           A+ +P  P  AP    T   A  L+ EE   K L     GP    + +       + S G
Sbjct: 455 ASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGG 514

Query: 457 FTSSPS-PFSSSSPENVEDSGLDSPSHAAPGPSPDSWVPRPGTP---QSPPSCRAPPPEA 512
              +P  P  S SP+      L   +  APG +P    P PG P   ++PPS  APP   
Sbjct: 515 DAPTPGVPTGSPSPD------LAPAAEPAPGAAPPPPPPLPGLPSPQEAPPS--APP--- 563

Query: 513 RGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAP 560
              +APPLP SP+P  + P P        GDL P P  P    G   P
Sbjct: 564 ---QAPPLPGSPEPPPAPPLP--------GDLPPPPPPPPPPPGTDGP 600



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 30/99 (30%), Positives = 37/99 (37%), Gaps = 14/99 (14%)

Query: 450 TGSSSLGFTSSPSPFSSSSPENVED-SGLDSPSHAAPGPSPDSWVPRPGTPQSPPSC--- 505
           TGS S     +  P   ++P       GL SP  A P   P +  P PG+P+ PP+    
Sbjct: 523 TGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQA-PPLPGSPEPPPAPPLP 581

Query: 506 ---------RAPPPEARGIRAPPLPDSPQPLASSPGPWG 535
                      PPP   G   PP P  P P    P   G
Sbjct: 582 GDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALG 620


>gi|223972704 hypothetical protein LOC284418 [Homo sapiens]
          Length = 922

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 109/455 (23%), Positives = 158/455 (34%), Gaps = 125/455 (27%)

Query: 481 SHAAPGPSPDSWVPRPGT--PQSPPSCRAPPPEARGI-----RAPPLPDSPQPLASSPGP 533
           S   P     SW P PG   PQ  P+  APP +A  +     +AP +P   Q   + P P
Sbjct: 419 SQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAP 478

Query: 534 WGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSA 593
                        A A P     + APP++        P             P+    + 
Sbjct: 479 -------SRKASAASASPRKASAVPAPPQKTPPPSQKAPSV-----------PTIPQKAV 520

Query: 594 ASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLARVTG 653
           + TA ++ S L          P+P    SQ ALP  T+ TEY  A      P+   ++ G
Sbjct: 521 SPTAPKKKSLLL---------PAP----SQKALP--TSPTEYQMAL---SPPASRGKLPG 562

Query: 654 ELTMTFPAGI------VRVFSGTPPPPVLSFRLVHTTAIEHF--------------QPNA 693
           +  +  P GI       R  SG  P PV++ R   T  +E                + + 
Sbjct: 563 DFDV-LPTGIPGRAVLERSQSGGKPEPVVTVRTQETDVVEMTTQAKSPESPFTVTKKESK 621

Query: 694 DLLFSDPSQSDPET------KDFWLNMAALTE--------------------ALQRQAEQ 727
           D+L S   +   E        + W + A L E                      +  A +
Sbjct: 622 DILISQTKEVTLEAFRGQGKLEDWAHWAKLEERSPDLPGVRSKELEQRKRWVKAKELAVE 681

Query: 728 NPTASY---YNVVLL-----------RYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYG 773
            P+  +   ++V  L           + Q S+    S+P  L A  Q  AT    SV   
Sbjct: 682 GPSQEHSRPFSVEALTLTKLMITANSKEQPSKSALVSLPSWLLATPQASATSMMASVP-- 739

Query: 774 YRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAA-TWNLEEKRLTWRLPDVSEAGGSGRL 832
            RPG           Q+ L  G+PV  VR QP + TW  E KR  W   ++ E       
Sbjct: 740 SRPG-----------QLSLLEGKPVV-VREQPESHTWVKEGKR-PW--GEMKEQPWGEMK 784

Query: 833 SASWEPLSGPSTP---SPVAAQFTSEGTTLSGVDL 864
              W+P   P  P    P +A    EG + + + L
Sbjct: 785 EPPWDPKGPPKVPFRSKPTSASLKREGISQAPIPL 819


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,912,717
Number of Sequences: 37866
Number of extensions: 2437987
Number of successful extensions: 19792
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 238
Number of HSP's successfully gapped in prelim test: 1496
Number of HSP's that attempted gapping in prelim test: 12409
Number of HSP's gapped (non-prelim): 5967
length of query: 889
length of database: 18,247,518
effective HSP length: 111
effective length of query: 778
effective length of database: 14,044,392
effective search space: 10926536976
effective search space used: 10926536976
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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