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Search of human proteins with 116174778
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116174778 centrosome spindle pole associated protein 1
isoform b [Homo sapiens]
(1221 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116174778 centrosome spindle pole associated protein 1 isofor... 2436 0.0
gi|116174789 centrosome spindle pole associated protein 1 isofor... 2419 0.0
gi|148746195 trichohyalin [Homo sapiens] 92 3e-18
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 84 1e-15
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 81 5e-15
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 78 4e-14
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 77 1e-13
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 76 2e-13
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 74 8e-13
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 73 2e-12
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 73 2e-12
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa... 70 1e-11
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa... 70 1e-11
gi|221219020 NYD-SP11 protein [Homo sapiens] 69 3e-11
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 69 4e-11
gi|4506467 radixin [Homo sapiens] 69 4e-11
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa... 68 5e-11
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa... 68 5e-11
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa... 68 6e-11
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap... 68 6e-11
gi|62244004 modulator of estrogen induced transcription isoform ... 67 8e-11
gi|63176611 modulator of estrogen induced transcription isoform ... 67 8e-11
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 67 1e-10
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 67 1e-10
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 67 1e-10
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 67 1e-10
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 67 1e-10
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 66 2e-10
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof... 66 2e-10
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 65 3e-10
>gi|116174778 centrosome spindle pole associated protein 1 isoform b
[Homo sapiens]
Length = 1221
Score = 2436 bits (6314), Expect = 0.0
Identities = 1221/1221 (100%), Positives = 1221/1221 (100%)
Query: 1 MLFPLQVAAVTSSVRDDPLEHCVSPRTRARSPEICKMADNLDEFIEEQKARLAEDKAELE 60
MLFPLQVAAVTSSVRDDPLEHCVSPRTRARSPEICKMADNLDEFIEEQKARLAEDKAELE
Sbjct: 1 MLFPLQVAAVTSSVRDDPLEHCVSPRTRARSPEICKMADNLDEFIEEQKARLAEDKAELE 60
Query: 61 SDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGSLGIDYGLSLPLGEDYERKK 120
SDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGSLGIDYGLSLPLGEDYERKK
Sbjct: 61 SDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGSLGIDYGLSLPLGEDYERKK 120
Query: 121 HKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPI 180
HKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPI
Sbjct: 121 HKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPI 180
Query: 181 GQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRI 240
GQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRI
Sbjct: 181 GQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRI 240
Query: 241 IKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFR 300
IKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFR
Sbjct: 241 IKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFR 300
Query: 301 YESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSA 360
YESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSA
Sbjct: 301 YESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSA 360
Query: 361 NQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKRREKDLELRVAASGAQD 420
NQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKRREKDLELRVAASGAQD
Sbjct: 361 NQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKRREKDLELRVAASGAQD 420
Query: 421 PEKSPDRLKQFSVAPRHFEEMIPPERPRIAFQTPLPPLSAPSVPPIPSVHPVPSQNEDLR 480
PEKSPDRLKQFSVAPRHFEEMIPPERPRIAFQTPLPPLSAPSVPPIPSVHPVPSQNEDLR
Sbjct: 421 PEKSPDRLKQFSVAPRHFEEMIPPERPRIAFQTPLPPLSAPSVPPIPSVHPVPSQNEDLR 480
Query: 481 SGLSSALGEMVSPRIAPLPPPPLLPPLATNYRTPYDDAYYFYGSRNTFDPSLAYYGSGMM 540
SGLSSALGEMVSPRIAPLPPPPLLPPLATNYRTPYDDAYYFYGSRNTFDPSLAYYGSGMM
Sbjct: 481 SGLSSALGEMVSPRIAPLPPPPLLPPLATNYRTPYDDAYYFYGSRNTFDPSLAYYGSGMM 540
Query: 541 GVQPAAYVSAPVTHQLAQPVVNTVGQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEA 600
GVQPAAYVSAPVTHQLAQPVVNTVGQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEA
Sbjct: 541 GVQPAAYVSAPVTHQLAQPVVNTVGQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEA 600
Query: 601 LQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMH 660
LQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMH
Sbjct: 601 LQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMH 660
Query: 661 RQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVF 720
RQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVF
Sbjct: 661 RQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVF 720
Query: 721 GEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYE 780
GEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYE
Sbjct: 721 GEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYE 780
Query: 781 EEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEET 840
EEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEET
Sbjct: 781 EEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEET 840
Query: 841 KHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEE 900
KHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEE
Sbjct: 841 KHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEE 900
Query: 901 KKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVR 960
KKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVR
Sbjct: 901 KKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVR 960
Query: 961 RQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKR 1020
RQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKR
Sbjct: 961 RQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKR 1020
Query: 1021 LNRIKMQEGAKVDLDAIPSAKVREQRMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIED 1080
LNRIKMQEGAKVDLDAIPSAKVREQRMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIED
Sbjct: 1021 LNRIKMQEGAKVDLDAIPSAKVREQRMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIED 1080
Query: 1081 DVLPPPSQLPSARERRRNKWKGLDIDSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRR 1140
DVLPPPSQLPSARERRRNKWKGLDIDSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRR
Sbjct: 1081 DVLPPPSQLPSARERRRNKWKGLDIDSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRR 1140
Query: 1141 LNEFHNKPINTDDESSLVDPDDIMKHIGDDGSNSVATEPWLRPGTSETLKRFMAEQLNQE 1200
LNEFHNKPINTDDESSLVDPDDIMKHIGDDGSNSVATEPWLRPGTSETLKRFMAEQLNQE
Sbjct: 1141 LNEFHNKPINTDDESSLVDPDDIMKHIGDDGSNSVATEPWLRPGTSETLKRFMAEQLNQE 1200
Query: 1201 QQQIPGKPGTFTWQGLSTAHG 1221
QQQIPGKPGTFTWQGLSTAHG
Sbjct: 1201 QQQIPGKPGTFTWQGLSTAHG 1221
>gi|116174789 centrosome spindle pole associated protein 1 isoform a
[Homo sapiens]
Length = 1256
Score = 2419 bits (6268), Expect = 0.0
Identities = 1221/1256 (97%), Positives = 1221/1256 (97%), Gaps = 35/1256 (2%)
Query: 1 MLFPLQVAAVTSSVRDDPLEHCVSPRTRARSPEICKMADNLDEFIEEQKARLAEDKAELE 60
MLFPLQVAAVTSSVRDDPLEHCVSPRTRARSPEICKMADNLDEFIEEQKARLAEDKAELE
Sbjct: 1 MLFPLQVAAVTSSVRDDPLEHCVSPRTRARSPEICKMADNLDEFIEEQKARLAEDKAELE 60
Query: 61 SDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGSLGIDYGLSLPLGEDYERKK 120
SDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGSLGIDYGLSLPLGEDYERKK
Sbjct: 61 SDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGSLGIDYGLSLPLGEDYERKK 120
Query: 121 HKLKEELRQDYRRYLTQ-----------------------------------ERLKLERN 145
HKLKEELRQDYRRYLTQ ERLKLERN
Sbjct: 121 HKLKEELRQDYRRYLTQGITQGKRKKNFLSTSETDPSTLGVSLPIGERLSAKERLKLERN 180
Query: 146 KEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDV 205
KEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDV
Sbjct: 181 KEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDV 240
Query: 206 LTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIP 265
LTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIP
Sbjct: 241 LTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIP 300
Query: 266 DRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGN 325
DRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGN
Sbjct: 301 DRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGN 360
Query: 326 MPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRK 385
MPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRK
Sbjct: 361 MPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRK 420
Query: 386 EKYRLELLEQMAEQQRNKRREKDLELRVAASGAQDPEKSPDRLKQFSVAPRHFEEMIPPE 445
EKYRLELLEQMAEQQRNKRREKDLELRVAASGAQDPEKSPDRLKQFSVAPRHFEEMIPPE
Sbjct: 421 EKYRLELLEQMAEQQRNKRREKDLELRVAASGAQDPEKSPDRLKQFSVAPRHFEEMIPPE 480
Query: 446 RPRIAFQTPLPPLSAPSVPPIPSVHPVPSQNEDLRSGLSSALGEMVSPRIAPLPPPPLLP 505
RPRIAFQTPLPPLSAPSVPPIPSVHPVPSQNEDLRSGLSSALGEMVSPRIAPLPPPPLLP
Sbjct: 481 RPRIAFQTPLPPLSAPSVPPIPSVHPVPSQNEDLRSGLSSALGEMVSPRIAPLPPPPLLP 540
Query: 506 PLATNYRTPYDDAYYFYGSRNTFDPSLAYYGSGMMGVQPAAYVSAPVTHQLAQPVVNTVG 565
PLATNYRTPYDDAYYFYGSRNTFDPSLAYYGSGMMGVQPAAYVSAPVTHQLAQPVVNTVG
Sbjct: 541 PLATNYRTPYDDAYYFYGSRNTFDPSLAYYGSGMMGVQPAAYVSAPVTHQLAQPVVNTVG 600
Query: 566 QNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAK 625
QNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAK
Sbjct: 601 QNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAK 660
Query: 626 LEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLD 685
LEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLD
Sbjct: 661 LEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLD 720
Query: 686 PNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEE 745
PNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEE
Sbjct: 721 PNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEE 780
Query: 746 KKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAE 805
KKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAE
Sbjct: 781 KKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAE 840
Query: 806 ERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP 865
ERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP
Sbjct: 841 ERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP 900
Query: 866 SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQER 925
SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQER
Sbjct: 901 SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQER 960
Query: 926 LLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRD 985
LLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRD
Sbjct: 961 LLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRD 1020
Query: 986 SETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQ 1045
SETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQ
Sbjct: 1021 SETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQ 1080
Query: 1046 RMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIEDDVLPPPSQLPSARERRRNKWKGLDI 1105
RMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIEDDVLPPPSQLPSARERRRNKWKGLDI
Sbjct: 1081 RMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIEDDVLPPPSQLPSARERRRNKWKGLDI 1140
Query: 1106 DSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRRLNEFHNKPINTDDESSLVDPDDIMK 1165
DSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRRLNEFHNKPINTDDESSLVDPDDIMK
Sbjct: 1141 DSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRRLNEFHNKPINTDDESSLVDPDDIMK 1200
Query: 1166 HIGDDGSNSVATEPWLRPGTSETLKRFMAEQLNQEQQQIPGKPGTFTWQGLSTAHG 1221
HIGDDGSNSVATEPWLRPGTSETLKRFMAEQLNQEQQQIPGKPGTFTWQGLSTAHG
Sbjct: 1201 HIGDDGSNSVATEPWLRPGTSETLKRFMAEQLNQEQQQIPGKPGTFTWQGLSTAHG 1256
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 92.0 bits (227), Expect = 3e-18
Identities = 110/478 (23%), Positives = 210/478 (43%), Gaps = 74/478 (15%)
Query: 598 QEALQQQIREREERRKKEREEKEEYEA-----KLEAEMRTYNPWGKGGGGAPLRDAKGNL 652
+E QQQ RER++R +E EEKE + K E +++ P + L++ +
Sbjct: 223 REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ----RELQEEE--- 275
Query: 653 ITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSS 712
L ++ RQ + + + + R L E E+ + Q +
Sbjct: 276 -EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE- 333
Query: 713 PFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQR 772
+L+ +Q+E + LR + EE+++ ++ RE+ E++ RR EQ+
Sbjct: 334 ---------RREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR--EQQ 382
Query: 773 ARIQQEYEEEQEKKREKE--EEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYC 830
R +Q+ EQ+ +RE++ EQ+L+ E+ +R ++ ++E + ++++EEE++ + +
Sbjct: 383 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQER 442
Query: 831 ERDNLIGEETKH---MRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPP 887
L E+ + +++ Q + +L+R + R E R Q
Sbjct: 443 REQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQ-- 500
Query: 888 VPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDI 947
R+ QLR E+E++ E R + + EE RLQ+RL S+ ++ ++ER +
Sbjct: 501 -ERREQQLRREQEERR------EQRLKRQEEEERLQQRL---RSEQQLRREQEERREQLL 550
Query: 948 FDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLE 1007
RL+ R Q K R+ E R D + E
Sbjct: 551 KREEEKRLEQERREQRLK------------------REQEERRDQLLKREE--------E 584
Query: 1008 IQQQALLREQQKRL-NRIKMQEGAKVDLDAIPSAKVREQRMPRDDTSDFLKNSLLESD 1064
+QQ L REQ++RL R+K +E ++ + + REQR+ R++ + + LL+S+
Sbjct: 585 RRQQRLKREQEERLEQRLKREE-----VERLEQEERREQRLKREEPEEERRQQLLKSE 637
Score = 82.0 bits (201), Expect = 3e-15
Identities = 120/576 (20%), Positives = 226/576 (39%), Gaps = 69/576 (11%)
Query: 584 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGA 643
E++ + ++ + QE +QQ RE++ ++E+EE+ E + + E E +
Sbjct: 311 EEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEE 370
Query: 644 PLRDAKGNLITDLNRMH--RQNIDAYHNPDARTYEDKRAVVSL--------DPNLATSNA 693
R+ + L R R+ R + R L + L
Sbjct: 371 ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQE 430
Query: 694 ENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLR-----------FQ 742
E + ++ Q + + E + +QE K L+ +
Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK 490
Query: 743 IEEKKQREEAERERLRIAEEKEERR-----LAEQRARIQQEYEEEQEKKREKEE--EQRL 795
+EE+++RE+ ER ++ E+EERR E+ R+QQ EQ+ +RE+EE EQ L
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLL 550
Query: 796 KNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCER--------------DNLIGEETK 841
K EE RL +ER++ +R K+E+EE+ + L+ ER L EE +
Sbjct: 551 KREEEKRLEQERRE--QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVE 608
Query: 842 HMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEK 901
+ Q L+ + + +R + S + + + R Q R+ +L+ EEE+
Sbjct: 609 RLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ---ERREQRLKREEEE 665
Query: 902 KNVIMEL-----SEMRKQLRSEERRLQER----------LLHMDSDDEIPIRKKERNPMD 946
+ + L E R+Q +EE + Q R ++S+ + K P
Sbjct: 666 ERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRK 725
Query: 947 IFDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMY-LDPPRDHHT 1005
R + Q RR+ L + H + ++ E R D + + + +
Sbjct: 726 QEGQRRRQEQEEKRRRRESELQWQEEERAH----RQQQEEEQRRDFTWQWQAEEKSERGR 781
Query: 1006 LEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQRMPRDDTSDFLKNSLLESDS 1065
+ + LREQ++R +++ +E + + +P + +EQR + + L E +
Sbjct: 782 QRLSARPPLREQRER--QLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQ 839
Query: 1066 AFIGAYGETYPAIEDDVLPPPSQLPSARERRRNKWK 1101
+ ED + + S +RR KW+
Sbjct: 840 LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWR 875
Score = 79.7 bits (195), Expect = 2e-14
Identities = 110/537 (20%), Positives = 236/537 (43%), Gaps = 88/537 (16%)
Query: 584 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGA 643
+++ + +Q LQ +E LQ++ RE+ R+++ER+ +EE + + E E
Sbjct: 896 QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQL------------ 943
Query: 644 PLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKS 703
LR+ + + RQ + + D + + + ++ +P + +
Sbjct: 944 -LREER-------EKRRRQERERQYRKDKKLQQKEEQLLGEEPE---KRRRQEREKKYRE 992
Query: 704 SGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEK 763
+Q + R E + ++++ ++ Q +K + ++ E + LR EE+
Sbjct: 993 EEELQQEEEQLLR--------EEREKRRRQEWER----QYRKKDELQQEEEQLLR--EER 1038
Query: 764 EERRLAEQRARIQQEYEEEQEKKR----EKEEEQRLKNEEHIRLAEERQKEAERKKKEEE 819
E+RRL E+ + ++E E +QE+++ E+E +R + E R EE Q+E E+ +EE
Sbjct: 1039 EKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP 1098
Query: 820 EKYNLQ-LQHYC-ERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHE 877
EK Q + C E + L EE + +R+ + + +L+R + ++ E
Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREER------EKRRRQELERQYREEEEVQQ--EE 1150
Query: 878 SSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQL--RSEERRLQERLLHMDSDDEI 935
+ R + P R+ +L + ++ EL + +QL +E+R QER ++E+
Sbjct: 1151 EQLLREE--PEKRRRQELERQYREEE---ELQQEEEQLLREEQEKRRQERERQYREEEEL 1205
Query: 936 PIRKKERNPMDIFDMARHRLQAPVRRQSP--------KGLDAATFQNVHDFNELKDRDSE 987
+K+++ D + + Q +++ KG + F+ + D ++L+DR S+
Sbjct: 1206 QRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED-SQLRDRQSQ 1264
Query: 988 TRVDLKFM---YLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVRE 1044
DL+ + + R+ QQ+ ++++L R + +E + D E
Sbjct: 1265 Q--DLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRD-----RKSQEE 1317
Query: 1045 QRMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIEDDVLPPPSQLPSARERRRNKWK 1101
+++ R++ + K E+D F E+ +L + P R+ R K++
Sbjct: 1318 KQLLREEREE--KRRRQETDRKF---------REEEQLLQEREEQPLRRQERDRKFR 1363
Score = 77.0 bits (188), Expect = 1e-13
Identities = 102/496 (20%), Positives = 203/496 (40%), Gaps = 91/496 (18%)
Query: 598 QEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLN 657
+ LQ Q ER R+++E E++ ++ + +AE ++ + PLR+ + L
Sbjct: 743 ESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRER---QLR 799
Query: 658 RMHRQNIDAYHNPDARTYEDKRA--------VVSLDPNLATSNAENLEDAANKSSGHMQT 709
RQ + P+ E +R + L+ E + + G +
Sbjct: 800 AEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQED 859
Query: 710 QSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQR------------EEAERERL 757
Q E + Q++ R+Q+EE+++R E+ +E+
Sbjct: 860 Q---------------ERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQ 904
Query: 758 RIAEEKEE--RRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKE----- 810
+ EE+EE R E+R R +QE + +E++ ++EEEQ L+ E R +ER+++
Sbjct: 905 LLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDK 964
Query: 811 --------------AERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNK 856
+R+++E E+KY + + E + L+ EE + R+ + +
Sbjct: 965 KLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQE-----WERQ 1019
Query: 857 IASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLR 916
K + + ++R E R Q R+ Q R EE EL + +QL
Sbjct: 1020 YRKKDELQQEEEQLLR---EEREKRRLQE-----RERQYREEE-------ELQQEEEQLL 1064
Query: 917 SEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSPKGL-DAATFQNV 975
EER + R + E RK+E + + R + R++ + + Q
Sbjct: 1065 GEERETRRR-----QELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE 1119
Query: 976 HDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLRE--QQKRLNRIKMQEGAKVD 1033
+ ++R+ R +L+ Y R+ ++ +++ LLRE +++R ++ Q + +
Sbjct: 1120 EEQLLREEREKRRRQELERQY----REEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
Query: 1034 LDAIPSAKVREQRMPR 1049
L +RE++ R
Sbjct: 1176 LQQEEEQLLREEQEKR 1191
Score = 75.9 bits (185), Expect = 2e-13
Identities = 137/645 (21%), Positives = 253/645 (39%), Gaps = 89/645 (13%)
Query: 584 EDKPKPSKQSLQSYQEAL---QQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGG 640
ED +QS Q Q L Q++ RE+E RR ++R+ E +LE E +
Sbjct: 1254 EDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE------- 1306
Query: 641 GGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAA 700
A RD K L R R+ D + E+++ L E
Sbjct: 1307 --AKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQ--------LLQEREEQPLRRQ 1356
Query: 701 NKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIA 760
+ + + +G F E E ++++QE + FL+ + + + Q E + + R
Sbjct: 1357 ERDRKFREEELRHQEQGRKFLEE--EQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDR 1414
Query: 761 EEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEE 820
+ +EE + ++ R ++ EEEQ+ +R++ E + L+ E+ +R R+ E + +E E
Sbjct: 1415 KFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQERE 1474
Query: 821 KYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSM 880
+ L H ERD EE + +R+ + ++ S Q P R F+ E
Sbjct: 1475 EQQL---HRQERDRKFLEEEQQLRRQERDRKFREQELRS--QEPE------RKFLEE--- 1520
Query: 881 SRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKK 940
+ QL ++ ++ + E ++R+Q R ++RR Q+R ++++ ++
Sbjct: 1521 -----------EQQLHRQQRQRKFLQEEQQLRRQERGQQRR-QDRDRKFREEEQL---RQ 1565
Query: 941 ERNPMDIFDMARHRL----QAPVRRQSPKGL---DAATFQNVHDFNELK-DRDSETRVDL 992
ER + R R + VRRQ + D + +L+ +RD + R D
Sbjct: 1566 EREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDE 1625
Query: 993 KFMYLDPPRDHHTLEIQQQAL---------LREQQKRLNRIKMQEGAKVDLDAIPSAKVR 1043
+ + + H E ++ L REQQ R +R + + L ++R
Sbjct: 1626 QLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR 1685
Query: 1044 EQRMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIEDDVLPPPSQLPSARE----RRRNK 1099
Q R + + E + F+ + + QL E RR+ +
Sbjct: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQER 1745
Query: 1100 W-KGLDIDSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRRLNEFHNKPINTDDESSLV 1158
+ K L+ + RP +E ++R +ER R+ E + +E L
Sbjct: 1746 YRKILEEEQLRP---------------EREEQQLRRQERDRKFRE-EEQLRQEREEQQLR 1789
Query: 1159 DPDDIMKHIGDDGSNSVATEPWLRPGTSETLKRFMAEQLNQEQQQ 1203
+ K ++ E LRP + R+ EQL E+Q+
Sbjct: 1790 SQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE 1834
Score = 68.9 bits (167), Expect = 3e-11
Identities = 94/441 (21%), Positives = 199/441 (45%), Gaps = 68/441 (15%)
Query: 601 LQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMH 660
L+++ + R+ER +K REE++ + + E ++ RD K + + ++
Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQE-----------RDRK--FLEEEQQLR 1495
Query: 661 RQNIDA-YHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNV 719
RQ D + + R+ E +R + + L H Q + F +
Sbjct: 1496 RQERDRKFREQELRSQEPERKFLEEEQQL-----------------HRQQRQRKFLQ--- 1535
Query: 720 FGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEY 779
E Q+++QE + R Q ++K REE E+LR +E+EE++L+ Q R ++
Sbjct: 1536 -----EEQQLRRQE--RGQQRRQDRDRKFREE---EQLR--QEREEQQLSRQE-RDRKFR 1582
Query: 780 EEEQEKKREKEEEQRLKNEEHIRLAEERQK---EAERKKKEEEE---KYNLQLQHYCERD 833
EEQ+ +R+++E + +++E+ +R E +Q+ E +RK +E+E+ + Q H ERD
Sbjct: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERD 1642
Query: 834 NLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKN 893
EE +R+ L++ K + + +++ + + + +
Sbjct: 1643 RKFLEEEPQLRRQER-EQQLRHDRDRKFREE---EQLLQEGEEQQLRRQERDRKFREEEQ 1698
Query: 894 QLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARH 953
QLR +E ++ + E ++R+Q + R +E+L +++ +++ R ++ +
Sbjct: 1699 QLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPE 1758
Query: 954 RLQAPVRRQ--SPKGLDAATFQNVHDFNELKDRDS--------ETRVDLKFMYLDP-PRD 1002
R + +RRQ K + + + +L+ ++S + R + + L P RD
Sbjct: 1759 REEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRD 1818
Query: 1003 HHTLEIQQQALLREQQKRLNR 1023
++Q L EQ++RL +
Sbjct: 1819 GKYRWEEEQLQLEEQEQRLRQ 1839
Score = 68.6 bits (166), Expect = 4e-11
Identities = 113/559 (20%), Positives = 221/559 (39%), Gaps = 114/559 (20%)
Query: 581 LIFEDKPKPSKQSLQ-SYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKG 639
L+ E+ K +Q L+ Y+E ++++++ EE+ +E +EK E
Sbjct: 1153 LLREEPEKRRRQELERQYRE--EEELQQEEEQLLREEQEKRRQE---------------- 1194
Query: 640 GGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDART-----YEDKRAVVSLDPNLATSNAE 694
R+ + +L R R+ Y + D R+ +E ++ D + E
Sbjct: 1195 ------RERQYREEEELQRQKRK--QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE 1246
Query: 695 NLEDAANKSSGHMQTQSSPFARGNVFGEP-------------------PTELQIKQQEL- 734
N E ++ + S ++ GE P E Q++++E
Sbjct: 1247 N-EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQK 1305
Query: 735 -----------YKNFLRFQIEEKKQREEAE---RERLRIAEEKEE---------RRLAEQ 771
K LR + EEK++R+E + RE ++ +E+EE R+ E+
Sbjct: 1306 EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
Query: 772 RARIQQE----YEEEQEKKREKEEEQRLKNEEHIRLAEERQ---KEAERKKKEEEEKYNL 824
R Q++ EEEQ +R++ E + LK E+ +R E Q ++ +RK +EEE++ +
Sbjct: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425
Query: 825 QLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSV---DSII---------- 871
Q ERD EE + +R+ L+ + + +R + ++
Sbjct: 1426 Q-----ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHR 1480
Query: 872 ----RSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLL 927
R F+ E R Q R+ +LR++E ++ + E ++ +Q R + +E+ L
Sbjct: 1481 QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQL 1540
Query: 928 HMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSPK---GLDAATFQNVHDFNELKDR 984
+ + ++R + + + R + + RQ L+ + + +
Sbjct: 1541 RRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMED 1600
Query: 985 DSETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAK--V 1042
+ + R L RD E +Q RE+Q ++ QE + L+ P +
Sbjct: 1601 EQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQ----QLHRQERDRKFLEEEPQLRRQE 1656
Query: 1043 REQRMPRDDTSDFLKNSLL 1061
REQ++ D F + L
Sbjct: 1657 REQQLRHDRDRKFREEEQL 1675
Score = 61.6 bits (148), Expect = 4e-09
Identities = 75/366 (20%), Positives = 152/366 (41%), Gaps = 31/366 (8%)
Query: 583 FEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGG 642
F ++ S++ + + E QQ R++R++K +E+++ + + R + K
Sbjct: 1503 FREQELRSQEPERKFLEEEQQL--HRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE 1560
Query: 643 APLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANK 702
LR + L+R R R E +R + + L +
Sbjct: 1561 EQLRQEREE--QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL----- 1613
Query: 703 SSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEE 762
Q + F + E Q+ +QE + FL + + ++Q E + R +
Sbjct: 1614 ----RQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKF 1669
Query: 763 KEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEE---RQKEAERKKKEEE 819
+EE +L ++ Q +E K RE+E++ R + E L EE R++E ERK +EEE
Sbjct: 1670 REEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEE 1729
Query: 820 EKYNLQLQHYCERDNLIGEET-KHMRQPSPIVPALQNKIASKLQRPPSV--DSIIRSFIH 876
QL+ E++ L +E + + + + P + + + +R + +R
Sbjct: 1730 -----QLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQERE 1784
Query: 877 ESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIP 936
E + +S + QLR E E++ ++R Q R + R +E L ++ ++
Sbjct: 1785 EQQLRSQESDRKFREEEQLRQEREEQ-------QLRPQQRDGKYRWEEEQLQLEEQEQRL 1837
Query: 937 IRKKER 942
++++R
Sbjct: 1838 RQERDR 1843
Score = 59.7 bits (143), Expect = 2e-08
Identities = 64/250 (25%), Positives = 110/250 (44%), Gaps = 24/250 (9%)
Query: 585 DKPKPSKQSLQSYQEALQQQIREREERRKKEREE----KEEYEAKL---EAEMRTYNPWG 637
D+ + ++ Q QE +QQ+R +E RK EE ++E E K E ++R
Sbjct: 1664 DRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELER 1723
Query: 638 KGGGGAPLRDAKGNLITDLNRMHRQNI--DAYHNPDARTYEDKRAVVSLDPNLATSNAEN 695
K LR T+ ++ RQ R +++ + + + E
Sbjct: 1724 KFREEEQLRQE-----TEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQ 1778
Query: 696 LEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFL----RFQIEEKKQREE 751
L + Q F + E Q++ Q+ + + Q+EE++QR
Sbjct: 1779 LRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLR 1838
Query: 752 AERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEA 811
ER+R AEE+ + E+ R +QE +E+E+KR +E E++L+ EEHIR +QKE
Sbjct: 1839 QERDRQYRAEEQFATQ--EKSRREEQELWQEEEQKRRQERERKLR-EEHIR---RQQKEE 1892
Query: 812 ERKKKEEEEK 821
+R ++ E K
Sbjct: 1893 QRHRQVGEIK 1902
Score = 59.3 bits (142), Expect = 2e-08
Identities = 84/409 (20%), Positives = 161/409 (39%), Gaps = 62/409 (15%)
Query: 671 DARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTEL--- 727
D R ED+R D L E+ + Q Q A G E L
Sbjct: 112 DRRQEEDQRRFEPRDRQLE-------EEPGQRRRQKRQEQERELAEGEEQSEKQERLEQR 164
Query: 728 --QIKQQELYKNFLRFQIEEKKQREEAE--------------------RERLRIAEEKEE 765
Q + +EL++ +Q E+++ EE + RE L + + E
Sbjct: 165 DRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE 224
Query: 766 RRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQ 825
+ ++R R + ++EE+EK+ K E K EE ++ EE Q++ E +EEEE+
Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ-EEEPQRQREL--QEEEEQLRKL 281
Query: 826 LQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQS 885
+ R+ E+ + + + Q + + Q R E + +
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341
Query: 886 PPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPM 945
R+ QLR E+E++ +L +++ R E++ +E+ L + ++ ++ R
Sbjct: 342 EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR--REQQLRREQQLRREQ 399
Query: 946 DIFDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHT 1005
+ + R + +RR+ Q + +L+ E R + K H
Sbjct: 400 QLRREQQLRREQQLRRE----------QQLRREQQLRREQEEERHEQK----------HE 439
Query: 1006 LEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQRMPRDDTSD 1054
E ++Q L REQ++R + +K +E + + R+Q++ RD +
Sbjct: 440 QERREQRLKREQEERRDWLKREEETERH-----EQERRKQQLKRDQEEE 483
Score = 58.2 bits (139), Expect = 5e-08
Identities = 73/316 (23%), Positives = 133/316 (42%), Gaps = 41/316 (12%)
Query: 744 EEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRL 803
EEK+ R + + L+ ++E++R E R R Q EE +++R+K +EQ + E
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDR--QLEEEPGQRRRQKRQEQERELAEGEEQ 154
Query: 804 AEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQR 863
+E++++ +R ++ +E+ Q Q + ER+ EE + LQ+ + +
Sbjct: 155 SEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQ-----------LQSCKGHETEE 203
Query: 864 PPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRA--EEEKKNVIMELSEMRKQLRSEERR 921
P + + R + E + R+ Q R EEE+K E + LR EE +
Sbjct: 204 FPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEK----EWRKRETVLRKEEEK 259
Query: 922 LQERLLHMD---SDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSPKGLDAATFQNVHDF 978
LQE ++E +RK ER + + Q +RR+
Sbjct: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQ--------------- 304
Query: 979 NELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKR----LNRIKMQEGAKVDL 1034
+ ++ E R + R E ++Q L REQ++R L R + +E + L
Sbjct: 305 QLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQL 364
Query: 1035 DAIPSAKVREQRMPRD 1050
+ REQ++ R+
Sbjct: 365 RREQEEERREQQLRRE 380
Score = 55.5 bits (132), Expect = 3e-07
Identities = 77/400 (19%), Positives = 161/400 (40%), Gaps = 29/400 (7%)
Query: 29 ARSPEICKMADNLDEFIEEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAK 88
A ++ K L E EE + E + E + Y E + + E + K
Sbjct: 894 ALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEE---QLQQEEEQLLREEREK 950
Query: 89 ENIPPNSQQTRGSLGIDYGLSLPLGEDYER-------KKHKLKEELRQDYRRYLTQERLK 141
+Q R + LGE+ E+ KK++ +EEL+Q+ + L +ER K
Sbjct: 951 RRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREK 1010
Query: 142 LERNKEYNQFLRGKEESSEKFRQV--EKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSE 199
R +E+ + R K+E ++ Q+ E+ + + Q ++ + + + Q E E
Sbjct: 1011 -RRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERE 1069
Query: 200 GPRKDVLTPSEAYEELLNQR-----RLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLK 254
R+ L EE L Q R E ++ R+ + E + R +++ E++ L+
Sbjct: 1070 TRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQL----LR 1125
Query: 255 HQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYT 314
+R + +R++ E + + + R + + +E++ ++R E + + ++
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR 1185
Query: 315 NDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKS------APDNETSKSANQDTCSPF 368
++ R + E + ++ R + +S P+ E + N+ C
Sbjct: 1186 EEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGR 1245
Query: 369 AGMLFGG-EDRELIQRRKEKYRLELLEQMAEQQRNKRREK 407
F ED +L R+ ++ LL + E+ R + R +
Sbjct: 1246 ENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRR 1285
Score = 53.5 bits (127), Expect = 1e-06
Identities = 69/329 (20%), Positives = 141/329 (42%), Gaps = 27/329 (8%)
Query: 114 EDYERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKS 173
E ER++ LK E + + ++RLK E+ + +Q L+ +EE ++ + E+ +
Sbjct: 541 EQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQ 600
Query: 174 QRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQ--RRLEEDRYRQL-- 229
+ ++ + +++ + + + E E R+ L SE EE Q RR +++R Q
Sbjct: 601 RLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLK 660
Query: 230 -DDEIELRNRRIIKKANEEVGISNLKHQ-----RFASKAGIPDRRFHRFNE-DRVFDRRY 282
++E E +R+ ++ EE L + R K+ IP ++ +E D + Y
Sbjct: 661 REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVY 720
Query: 283 HRPDQDP---EVSEEMDERFRYESDF----DRRLSRVYTNDRMHRNKRGNMPPMEHDGDV 335
RP + E+ ++R R ES+ + R R + R+ E
Sbjct: 721 SRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERG 780
Query: 336 IEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLEL-LE 394
++ + R E + + + P E+ E QRR+++ E L+
Sbjct: 781 RQRLSARPPLREQRERQLRAEERQQREQRFLP--------EEEEKEQRRRQRREREKELQ 832
Query: 395 QMAEQQRNKRREKDLELRVAASGAQDPEK 423
+ E+++ +RRE+ +L+ G Q+ ++
Sbjct: 833 FLEEEEQLQRRERAQQLQEEEDGLQEDQE 861
Score = 52.8 bits (125), Expect = 2e-06
Identities = 62/321 (19%), Positives = 140/321 (43%), Gaps = 29/321 (9%)
Query: 117 ERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKE----------ESSEKFRQVE 166
+ ++++ +E+L+Q+ + L +ER K R + Q+ + K+ E EK R+ E
Sbjct: 926 QERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE 985
Query: 167 KSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPR----KDVLTPSEAYEELLNQRRLE 222
+ K R ++ + Q + L + + E R KD L E E+LL + R
Sbjct: 986 RE---KKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEE--EQLLREER-- 1038
Query: 223 EDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRY 282
++ R + E + R +++ E++ L +R + +R++ + E + + +
Sbjct: 1039 -EKRRLQERERQYREEEELQQEEEQL----LGEERETRRRQELERQYRKEEELQQEEEQL 1093
Query: 283 HRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIR 342
R + + +E + + R E + + ++ +R R +R + + + ++Q +
Sbjct: 1094 LREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR-RRQELERQYREEEEVQQEEEQ 1152
Query: 343 ISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRN 402
+ E + E + ++ E++E +RR+E+ R E+ ++Q+
Sbjct: 1153 LLREEPEKRRRQELERQYREEEELQQEEEQLLREEQE--KRRQERERQYREEEELQRQKR 1210
Query: 403 KRREKDLELRVAASGAQDPEK 423
K+R +D + R +PEK
Sbjct: 1211 KQRYRDEDQRSDLKWQWEPEK 1231
Score = 52.0 bits (123), Expect = 3e-06
Identities = 81/372 (21%), Positives = 158/372 (42%), Gaps = 63/372 (16%)
Query: 727 LQIKQQELYKNFLRFQIEEKKQREEA--ERERLRIAEEKE------------------ER 766
LQ ++QE ++ RF+ +++ EE R + R +E+E +
Sbjct: 110 LQDRRQE--EDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQ 167
Query: 767 RLAEQRARIQQEYEEEQEKKREKEEEQRLK--------NEEHIR---LAEERQKEAERKK 815
R E+ R +QE++E +E++ E+E+ Q K +EE +R L E R+K E K+
Sbjct: 168 RRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQ 227
Query: 816 KEEEEKYNLQLQ-----HYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSI 870
++ E+ + Q + +R+ ++ +E + +++ P + + + +
Sbjct: 228 QQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP------QRQRELQEEEEQLRKL 281
Query: 871 IRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMD 930
R + Q R+ QLR ++E E R++ + E R QER +
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQE---------EERREQQEERREQQERREQQE 332
Query: 931 SDDEIPIRK--KERNPMDI-FDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSE 987
E +R+ +ER + + R + +RR+ + Q + +L+ R+ +
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERREQQLRREQE---EERREQQLRREQQLR-REQQ 388
Query: 988 TRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQRM 1047
R + + R L +QQ L REQQ R + +E + + + REQR+
Sbjct: 389 LRREQQLRREQQLRREQQLRREQQ-LRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447
Query: 1048 PR--DDTSDFLK 1057
R ++ D+LK
Sbjct: 448 KREQEERRDWLK 459
Score = 52.0 bits (123), Expect = 3e-06
Identities = 62/279 (22%), Positives = 116/279 (41%), Gaps = 23/279 (8%)
Query: 584 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGA 643
+++ + ++ Q QE +QQ+ +E RK EE + + E ++R
Sbjct: 1615 QERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQ 1674
Query: 644 PLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAEN-------L 696
L++ + L R R R E +R + + L E L
Sbjct: 1675 LLQEGEEQ---QLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQL 1731
Query: 697 EDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNF-----LRFQIEEKKQREE 751
+ Q + E Q+++QE + F LR + EE++ R +
Sbjct: 1732 RQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791
Query: 752 AE----RERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEER 807
RE ++ +E+EE++L Q+ + +EEEQ + E+E+ R + + R AEE+
Sbjct: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR-AEEQ 1850
Query: 808 QKEAERKKKEEEEKYNLQLQ-HYCERDNLIGEETKHMRQ 845
E+ ++EE+E + + Q ER+ + EE H+R+
Sbjct: 1851 FATQEKSRREEQELWQEEEQKRRQERERKLREE--HIRR 1887
Score = 50.8 bits (120), Expect = 8e-06
Identities = 76/383 (19%), Positives = 155/383 (40%), Gaps = 78/383 (20%)
Query: 46 EEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGSLGID 105
+EQ+ + ED+ +L +++ + K E+ ++L ++ + + +
Sbjct: 1591 QEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKF----- 1645
Query: 106 YGLSLPLGEDYERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQV 165
L E+ + ++ + +++LR D R +E L+ +E Q LR ++E KFR+
Sbjct: 1646 ------LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEE--QQLR-RQERDRKFREE 1696
Query: 166 EKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDR 225
E+ + +R +K + + + +++ E R+ E +E L + ++R
Sbjct: 1697 EQQLR-RQERERKFLQEEQQLRRQELERKFREEEQLRQ------ETEQEQLRR----QER 1745
Query: 226 YRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRP 285
YR++ +E +LR R EE L+ Q R +F E+ R R
Sbjct: 1746 YRKILEEEQLRPER------EE---QQLRRQE----------RDRKFREEEQL--RQERE 1784
Query: 286 DQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVI-EQSNIRIS 344
+Q S+E D +FR E R R ++ + P + DG E+ +++
Sbjct: 1785 EQQLR-SQESDRKFREEEQL-----------RQEREEQ-QLRPQQRDGKYRWEEEQLQLE 1831
Query: 345 SAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKR 404
E + + + A + + +EK R E E E+++ +R
Sbjct: 1832 EQEQRLRQERDRQYRAEEQFAT------------------QEKSRREEQELWQEEEQKRR 1873
Query: 405 REKDLELRVAASGAQDPEKSPDR 427
+E++ +LR Q E+ R
Sbjct: 1874 QERERKLREEHIRRQQKEEQRHR 1896
Score = 50.1 bits (118), Expect = 1e-05
Identities = 84/393 (21%), Positives = 161/393 (40%), Gaps = 64/393 (16%)
Query: 114 EDYERKKHKLKEELRQD-YRRYLTQERLKLERNK-------------EYNQFLRGKEESS 159
++ ERK + +++LRQ+ +R++ +E+L ER + E Q LR ++E
Sbjct: 1442 QERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLR-RQERD 1500
Query: 160 EKFRQVE-KSTEPKS-----------QRNKKPIGQVKPDLTSQIQTSCENSEGPRK---- 203
KFR+ E +S EP+ Q+ ++ Q + L Q + + RK
Sbjct: 1501 RKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE 1560
Query: 204 DVLTPSEAYEELLNQRR-----LEEDRYRQ-------LDDEIELRNRRIIKKANEEVGIS 251
+ L ++L Q R LEE + R+ ++DE +LR + ++ +E
Sbjct: 1561 EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRK 1620
Query: 252 NLKHQRFASKAGIPDRRFHRFNEDRVF---DRRYHRPDQDPEVSEEMDERFRYESDF--- 305
+ ++ + +++ HR DR F + + R +++ ++ + D +FR E
Sbjct: 1621 FREDEQLLQER--EEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQE 1678
Query: 306 -DRRLSRVYTNDRMHRNKRGNMPPMEHDGDVI-EQSNIRISSAENKSAPDNETSKSANQD 363
+ + R DR R + + E + + E+ +R E K + + + Q+
Sbjct: 1679 GEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE 1738
Query: 364 TCSPFAGMLFGGEDRELIQRRKE----------KYRLE-LLEQMAEQQRNKRREKDLELR 412
E+ +L R+E K+R E L Q E+Q+ + +E D + R
Sbjct: 1739 QLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFR 1798
Query: 413 VAASGAQDPEKSPDRLKQFSVAPRHFEEMIPPE 445
Q+ E+ R +Q R EE + E
Sbjct: 1799 EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLE 1831
Score = 48.1 bits (113), Expect = 5e-05
Identities = 61/340 (17%), Positives = 138/340 (40%), Gaps = 34/340 (10%)
Query: 111 PLGEDYERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQV----E 166
P ++ RK+ +L +E ++ +R ++R + E+ ++Y + + ++E + R+
Sbjct: 893 PALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRR 952
Query: 167 KSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRK----DVLTPSEAY---EELLNQR 219
+ + R K + Q + L + E +K + L E EE +R
Sbjct: 953 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1012
Query: 220 RLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFD 279
R E +R + DE++ +++++ E+ + + +++ + + E+R
Sbjct: 1013 RQEWERQYRKKDELQQEEEQLLREEREKRRLQE-RERQYREEEELQQEEEQLLGEERETR 1071
Query: 280 RRYHRPDQ---DPEVSEEMDERFRYESDFDRRLSR----------VYTNDRMHRNKRGNM 326
RR Q + E+ +E ++ R E + RR R +++ R +R
Sbjct: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131
Query: 327 PPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKE 386
E + E+ ++ E + E K Q+ + E+ EL Q ++
Sbjct: 1132 RRQELERQYREEEEVQ---QEEEQLLREEPEKRRRQELERQYR------EEEELQQEEEQ 1182
Query: 387 KYRLELLEQMAEQQRNKRREKDLELRVAASGAQDPEKSPD 426
R E ++ E++R R E++L+ + +D ++ D
Sbjct: 1183 LLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSD 1222
Score = 48.1 bits (113), Expect = 5e-05
Identities = 66/349 (18%), Positives = 143/349 (40%), Gaps = 54/349 (15%)
Query: 114 EDYERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKE--------------ESS 159
E E+K+ K ++ Q+ ++ L +ER + R +E ++ R +E E
Sbjct: 1300 EREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERD 1359
Query: 160 EKFRQVEKSTEPKSQRNKKPIGQVKPD------LTSQIQTSCENSEGPRKDVLTPSEAYE 213
KFR+ E + + ++ + +++ L + Q C+ E + E
Sbjct: 1360 RKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREE 1419
Query: 214 ELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGI----PDRRF 269
E R+ + ++R+ + ++ R R K EE + +H++F + + +++
Sbjct: 1420 EQQLSRQERDRKFREEEQQVR-RQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQL 1478
Query: 270 HRFNEDRVF---DRRYHRPDQDPEV------SEEMDERFRYESDFDRRLSR----VYTND 316
HR DR F +++ R ++D + S+E + +F E R R +
Sbjct: 1479 HRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQ 1538
Query: 317 RMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGE 376
++ R +RG + D E+ +R E + + K F E
Sbjct: 1539 QLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRK--------------FRLE 1584
Query: 377 DRELIQRRKEKYRLELLEQMAEQ--QRNKRREKDLELRVAASGAQDPEK 423
++++ ++ +E+ +E +Q+ Q Q+ R+E+D + R Q+ E+
Sbjct: 1585 EQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREE 1633
Score = 47.8 bits (112), Expect = 7e-05
Identities = 60/304 (19%), Positives = 132/304 (43%), Gaps = 22/304 (7%)
Query: 112 LGEDYERKKHKLKEELRQDYRRYLTQERL-KLERNKEYNQFLRGKEESSEKFRQVEKSTE 170
L + ER++ +LK E + + L +E + +LE+ + Q L+ +E E+ +Q+ KS E
Sbjct: 579 LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEE 638
Query: 171 PKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLD 230
+ +R + Q++ + R E E+ L + EE R ++L
Sbjct: 639 QEERRQQ------------QLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELA 686
Query: 231 DEIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPE 290
+E + + R IK + L+ + A ++ + R + + R ++ R ++ E
Sbjct: 687 EEEQEQARERIKSRIPK-WQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESE 745
Query: 291 VSEEMDER-FRYESDFDRRLSRVYTNDRMHRNKRGNM-----PPMEHDGDVIEQSNIRIS 344
+ + +ER R + + ++R + +++RG PP+ + ++ R
Sbjct: 746 LQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEER-Q 804
Query: 345 SAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKR 404
E + P+ E + + + F E+ E +QRR+ +L+ E ++ + +R
Sbjct: 805 QREQRFLPEEEEKEQRRRQRREREKELQF-LEEEEQLQRRERAQQLQEEEDGLQEDQERR 863
Query: 405 REKD 408
R ++
Sbjct: 864 RSQE 867
Score = 45.8 bits (107), Expect = 2e-04
Identities = 71/338 (21%), Positives = 140/338 (41%), Gaps = 38/338 (11%)
Query: 114 EDYER-KKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPK 172
E+ ER ++ + K++L++D + LKLE + Q +E ++ R+ ++ +
Sbjct: 462 EETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQ----QERREQQLRREQEERREQ 517
Query: 173 SQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQ-LDD 231
+ ++ +++ L S+ Q E E R++ L E ++RLE++R Q L
Sbjct: 518 RLKRQEEEERLQQRLRSEQQLRREQEE--RREQLLKRE------EEKRLEQERREQRLKR 569
Query: 232 EIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPE- 290
E E R +++K+ E + Q + + R ++ ++R R + + E
Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER 629
Query: 291 -----VSEEMDERFR------YESDFDRRLSRVYTNDRM-------HRNKRGNMPPMEHD 332
SEE +ER + + ++RL R +R+ H +R E +
Sbjct: 630 RQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE 689
Query: 333 GDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLEL 392
EQ+ RI S K E+ A Q G R+ + ++ + EL
Sbjct: 690 Q---EQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESEL 746
Query: 393 LEQMAEQQRNKRREKDLELRVAASGAQDPEKSPDRLKQ 430
Q E++R R++++ E R + E+ +R +Q
Sbjct: 747 --QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQ 782
Score = 41.6 bits (96), Expect = 0.005
Identities = 75/346 (21%), Positives = 136/346 (39%), Gaps = 51/346 (14%)
Query: 114 EDYERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKS 173
E ER++ +LK E ++ ++RLK E +E + +EE E+ R+ KS PK
Sbjct: 650 EQQERREQRLKREEEEER----LEQRLKREHEEERREQELAEEEQ-EQARERIKSRIPKW 704
Query: 174 QRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDR-YRQLDDE 232
Q + + S++ + EG R+ + + EE+R +RQ +E
Sbjct: 705 QWQLESEADARQ---SKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE 761
Query: 233 IELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVS 292
+ R+ +A E+ S QR +++ P R R + R +R+ PE
Sbjct: 762 EQRRDFTWQWQAEEK---SERGRQRLSAR---PPLREQRERQLRAEERQQREQRFLPE-E 814
Query: 293 EEMDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSA------ 346
EE ++R R + ++ L + +++ R +R E DG +Q R
Sbjct: 815 EEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKW 874
Query: 347 ------ENKSAPDNETSKSANQDTCSPFAGMLFGGEDR---------------------E 379
E K +K A Q+ +L E+ E
Sbjct: 875 RWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEE 934
Query: 380 LIQRRKEKYRLELLEQMAEQQRNK--RREKDLELRVAASGAQDPEK 423
+Q+ +E+ E E+ Q+R + R++K L+ + ++PEK
Sbjct: 935 QLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEK 980
Score = 41.2 bits (95), Expect = 0.006
Identities = 72/335 (21%), Positives = 124/335 (37%), Gaps = 75/335 (22%)
Query: 106 YGLSLPLGEDYERK-----KHKLKEELRQ--DYRRYLTQERL--------KLERNKEYNQ 150
Y L G D E++ K L ++ RQ D RR+ ++R + ++ +E +
Sbjct: 87 YALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQER 146
Query: 151 FLRGKEESSEKFRQVEKSTEPKS------QRNKKPIGQVKPDLTSQIQTSC---ENSEGP 201
L EE SEK ++E+ + QR + + + Q+Q SC E E P
Sbjct: 147 ELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQ-SCKGHETEEFP 205
Query: 202 RKDVLTPSEAYE-------ELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLK 254
++ L E E E QRR +DR Q ++E E R R + + EE
Sbjct: 206 DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE------- 258
Query: 255 HQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYT 314
+ E+ P + E+ EE +E+ R + R R
Sbjct: 259 ----------------KLQEE--------EPQRQRELQEE-EEQLRKLERQELRRERQEE 293
Query: 315 NDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFG 374
+ R +R + + + EQ R E + + + ++
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQ---------- 343
Query: 375 GEDRELIQRRKEKYRLELLEQMAEQQRNKRREKDL 409
E+R Q R+E+ +Q+ +Q +RRE+ L
Sbjct: 344 -EERREQQLRREQEEERREQQLRREQEEERREQQL 377
Score = 41.2 bits (95), Expect = 0.006
Identities = 48/216 (22%), Positives = 94/216 (43%), Gaps = 26/216 (12%)
Query: 602 QQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHR 661
+QQ+R +E RK EE+ E + E ++R + K LR + + ++ R
Sbjct: 1713 EQQLRRQELERKFREEEQLRQETEQE-QLRRQERYRKILEEEQLRPER-----EEQQLRR 1766
Query: 662 QNIDAYHNPDARTYEDKRAVVSLDPNLATSNAEN-LEDAANKSSGHMQTQSSPFARGNVF 720
Q D + + +++ + L + ++ + + Q P R +
Sbjct: 1767 QERDRKFREEEQLRQERE-----EQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKY 1821
Query: 721 GEPPTELQIKQQEL---------YKNFLRFQIEEKKQREEAE--RERLRIAEEKEERRLA 769
+LQ+++QE Y+ +F +EK +REE E +E + ++ ER+L
Sbjct: 1822 RWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLR 1881
Query: 770 EQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAE 805
E+ R QQ +E+++ R+ E + + + H RL E
Sbjct: 1882 EEHIRRQQ---KEEQRHRQVGEIKSQEGKGHGRLLE 1914
Score = 40.8 bits (94), Expect = 0.008
Identities = 67/323 (20%), Positives = 133/323 (41%), Gaps = 56/323 (17%)
Query: 117 ERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRN 176
E++ + +EE R + + + +L+R +E + +EE +E+ Q +R
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQ---------ERR 472
Query: 177 KKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELR 236
K+ Q+K D E R++ E E +R +E R +QL E E R
Sbjct: 473 KQ---QLKRD-----------QEEERRERWLKLEEEE----RREQQERREQQLRREQEER 514
Query: 237 NRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNE--DRVFDRRYHRPDQDPEVSEE 294
+ +K+ EE + QR S+ + + R + R ++R + ++ + E
Sbjct: 515 REQRLKRQEEEERL----QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKRE 570
Query: 295 MDER-----FRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENK 349
+ER R E +RL R R KR + +E + E+ R+ E +
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQE----ERREQRLKREEPE 626
Query: 350 SAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQR---NKRRE 406
+ KS Q+ ++ ++R +++ R + L++ E++R +RE
Sbjct: 627 EERRQQLLKSEEQEE-----------RRQQQLRREQQERREQRLKREEEEERLEQRLKRE 675
Query: 407 KDLELRVAASGAQDPEKSPDRLK 429
+ E R ++ E++ +R+K
Sbjct: 676 HEEERREQELAEEEQEQARERIK 698
Score = 38.1 bits (87), Expect = 0.052
Identities = 69/353 (19%), Positives = 137/353 (38%), Gaps = 30/353 (8%)
Query: 114 EDYERKKHKLKEELRQDYRRYLTQER-LKLERNKEYNQFLRGKEESSEKFRQVEKSTEPK 172
++ ER++ +L+ E + + L +E+ L+ E+ Q LR +E+ + +Q+ + + +
Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR-REQQLRREQQLRREQQLR 426
Query: 173 SQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDE 232
++ ++ Q + + E E R+D L E E R +E R +QL +
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEE--RRDWLKREEETE-----RHEQERRKQQLKRD 479
Query: 233 IELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVS 292
E R K EE + + + +RR R +R R + ++
Sbjct: 480 QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539
Query: 293 EEMDERFRY--ESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAEN-- 348
E +ER + + ++RL + R+ R + + + Q ++ E
Sbjct: 540 REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 599
Query: 349 KSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELL---EQMAEQQRNKRR 405
+ E + ++ E R + +E+ R +LL EQ +Q+ RR
Sbjct: 600 QRLKREEVERLEQEER----------REQRLKREEPEEERRQQLLKSEEQEERRQQQLRR 649
Query: 406 EKDLELRVAASGAQDPEKSPDRLKQFSVAPRHFEEMIPPE----RPRIAFQTP 454
E+ ++ E+ RLK+ R +E+ E R RI + P
Sbjct: 650 EQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 83.6 bits (205), Expect = 1e-15
Identities = 76/360 (21%), Positives = 162/360 (45%), Gaps = 16/360 (4%)
Query: 584 EDKPKPSKQSLQSYQEALQQQ---IREREERRKKEREEKEEYEAKLEA-EMRTYNPWGKG 639
E+K + ++ +Q +E +++Q IRE+EE+ +++ E E E K+ E + K
Sbjct: 367 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 426
Query: 640 GGGAPLRDAKGNLITDLN-RMH-----RQNIDAYHNPDARTYEDKRAVVSLDPNLATSNA 693
+ K I +L +MH R+ + + ++KR
Sbjct: 427 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 486
Query: 694 ENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEK--KQREE 751
E+ + M Q E E + +Q+E+++ + + +E+ +Q+E+
Sbjct: 487 REQEEKIREQEEKMWRQEEKIHEQEKIREE--EKRQEQEEMWRQEEKIREQEEIWRQKEK 544
Query: 752 AERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEA 811
+ +I +++E+ E++ Q+E EQE+K ++EE+ + EE IR EE+ +E
Sbjct: 545 IHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQ 604
Query: 812 ERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSII 871
E +E+EEK Q + CE++ + E+ + MR+ + + KI + ++ + ++
Sbjct: 605 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 664
Query: 872 RSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDS 931
+ E M + + EE+ + ++ E +LR +E ++QE H+++
Sbjct: 665 QE--QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
Score = 66.2 bits (160), Expect = 2e-10
Identities = 78/329 (23%), Positives = 145/329 (44%), Gaps = 48/329 (14%)
Query: 726 ELQIKQQELYKNFLRFQIEEKKQREEA---------ERERLRIAEEKEERRLAEQRARIQ 776
+ Q+++ EL+ N L Q EEK R+E + + +I E++E+ R E++ R Q
Sbjct: 343 QAQVEENELW-NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ 401
Query: 777 QEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLI 836
+E E+E+K ++EE + EE +R EE E E K +E EEK + E++ +
Sbjct: 402 EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH-------EQEKIR 454
Query: 837 GEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLR 896
+E K + KI + +R + R + R Q + ++ ++
Sbjct: 455 EQEEKRQE---------EEKIREQEKRQEQEAKMWR----QEEKIREQEEKIREQEEKMW 501
Query: 897 AEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQ 956
+EEK + ++ E K+ EE QE + + E R+KE+ H +
Sbjct: 502 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR---EQEEIWRQKEK---------IHEQE 549
Query: 957 APVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLRE 1016
+R+Q K + +HD E K R+ E +V + + R+ +Q+ +RE
Sbjct: 550 EKIRKQEEKMWRQE--EKMHD-QEEKIREQEEKV---WRQEEKIREQEEKIREQEEKIRE 603
Query: 1017 QQKRLNRIKMQEGAKVDLDAIPSAKVREQ 1045
Q++ + + G + + K++EQ
Sbjct: 604 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 632
Score = 55.1 bits (131), Expect = 4e-07
Identities = 48/241 (19%), Positives = 109/241 (45%), Gaps = 27/241 (11%)
Query: 584 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGA 643
E+K + ++ + +E + +Q + REE +++E+EE E K+ + + K
Sbjct: 490 EEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK----- 544
Query: 644 PLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKS 703
+ + + + +M RQ + H+ + + E + V + + + E
Sbjct: 545 -IHEQEEKIRKQEEKMWRQE-EKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIR 602
Query: 704 SGHMQTQSSPFARGNV---FGEPPTELQIKQQELYKNFLRFQIEEKKQREEAE--RERLR 758
TQ G E ++Q +++++ + + + +EKK RE+ E RE+
Sbjct: 603 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 662
Query: 759 IAEEKEER------RLAEQRARIQQEYEE---------EQEKKREKEEEQRLKNEEHIRL 803
+ +E+EE+ ++ EQ ++Q++ E+ EQE + ++EE+ +++EH+
Sbjct: 663 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
Query: 804 A 804
A
Sbjct: 723 A 723
Score = 54.7 bits (130), Expect = 5e-07
Identities = 81/427 (18%), Positives = 182/427 (42%), Gaps = 51/427 (11%)
Query: 42 DEFIEEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGS 101
DE ++E+ A+L E +ES+ +++ K + E +K+L +P Q
Sbjct: 277 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLL-------LPQQQLQAEAD 329
Query: 102 LGIDYGLSLPLGEDYERKKHKLKEELRQD--YRRYLTQERLKLERNKEYNQFLRGK-EES 158
LG++ + KL+ ++ ++ + R Q+ K+ R +E Q K +E
Sbjct: 330 ---------HLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 380
Query: 159 SEKFRQVE---KSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEEL 215
EK R+ E + E K +R ++ + + + + Q + E E R+ E E++
Sbjct: 381 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 440
Query: 216 --LNQRRLEEDRYRQLD----DEIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRF 269
L ++ E+++ R+ + +E ++R + ++ ++ K + K + +
Sbjct: 441 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKM 500
Query: 270 HRFNEDRVFDRRYHRPDQDPEVSEEM---DERFRYESDFDRRLSRVYTNDRMHRNKRGNM 326
R E+++ ++ R ++ + EEM +E+ R + + R+ +++ + R + M
Sbjct: 501 WR-QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKM 559
Query: 327 ----PPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQ 382
M + I + ++ E K E + + E E+ Q
Sbjct: 560 WRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKI----------REQEEMTQ 609
Query: 383 RRKEKYRLELLEQMAEQQRNKRREKDLELRVAASGAQDPEKSPDRLKQFSVAPRHFEEMI 442
++EK E E+M EQ+ K +E++ ++R ++ EK ++++ R EEM+
Sbjct: 610 EQEEKMG-EQEEKMCEQE-EKMQEQEEKMRRQEEKIREQEK---KIREQEEKIREQEEMM 664
Query: 443 PPERPRI 449
+ ++
Sbjct: 665 QEQEEKM 671
Score = 42.0 bits (97), Expect = 0.004
Identities = 61/325 (18%), Positives = 126/325 (38%), Gaps = 17/325 (5%)
Query: 117 ERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFR-QVEKSTEPKSQR 175
E K + +E + + + QE + E+ ++ + L K EK R Q EK E + R
Sbjct: 409 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE-LEEKMHEQEKIREQEEKRQEEEKIR 467
Query: 176 NKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIEL 235
++ + + + Q + E E R+ E++ Q ++ E+ RQ +E+
Sbjct: 468 EQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWR 527
Query: 236 RNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEM 295
+ +I + EE+ K K + + R E+++ D+ +Q+ +V +
Sbjct: 528 QEEKI--REQEEIWRQKEKIHEQEEKIRKQEEKMWR-QEEKMHDQEEKIREQEEKVWRQE 584
Query: 296 DERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNE 355
++ E + ++ + M + + M E + + EQ ++ E K E
Sbjct: 585 EKIREQEEKIREQEEKIREQEEMTQEQEEKMG--EQEEKMCEQEE-KMQEQEEKMRRQEE 641
Query: 356 TSKSANQDTCSPFAGMLFGGEDRELIQRRKEKY------RLELLEQMAEQQRNKRREKDL 409
+ + + E E++Q ++EK E E+M EQ+ RR+++
Sbjct: 642 KIREQEKKIREQEEKIR---EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 698
Query: 410 ELRVAASGAQDPEKSPDRLKQFSVA 434
Q EK + + A
Sbjct: 699 MWEQEVRLRQQEEKMQEHQEHLEAA 723
Score = 34.7 bits (78), Expect = 0.57
Identities = 70/374 (18%), Positives = 151/374 (40%), Gaps = 43/374 (11%)
Query: 42 DEFIEEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGS 101
+E I+EQ+ ++ E + ++ M + ++ + E + M E +Q
Sbjct: 374 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 433
Query: 102 LGIDYGLSLPLGEDYERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKE----- 156
+ + + +E++K + +EE RQ+ + QE+ + + K + Q + +E
Sbjct: 434 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 493
Query: 157 -ESSEK-FRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEE 214
E EK +RQ EK E + R ++ Q + ++ Q + E E R+ + +E+
Sbjct: 494 REQEEKMWRQEEKIHEQEKIREEEK-RQEQEEMWRQEEKIREQEEIWRQ----KEKIHEQ 548
Query: 215 LLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNE 274
R+ EE +RQ + + + I++ E+V K + K R E
Sbjct: 549 EEKIRKQEEKMWRQEEKMHDQEEK--IREQEEKVWRQEEKIREQEEKI--------REQE 598
Query: 275 DRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGD 334
+++ ++ +Q+ ++ E+ ++ E + ++ + R E +
Sbjct: 599 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIR---------EQEKK 649
Query: 335 VIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLE 394
+ EQ +I E E + C E E +Q ++EK R + E
Sbjct: 650 IREQEE-KIREQEEMMQEQEEKMWEQEEKMC----------EQEEKMQEQEEKMRRQ-EE 697
Query: 395 QMAEQQRNKRREKD 408
+M EQ+ R++++
Sbjct: 698 KMWEQEVRLRQQEE 711
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 81.3 bits (199), Expect = 5e-15
Identities = 82/366 (22%), Positives = 168/366 (45%), Gaps = 32/366 (8%)
Query: 591 KQSLQSYQEALQQQIREREERRKKEREEK-EEYEAKLEAEMRTYNPWGKGGGGAPLRDAK 649
++ ++ +E + +Q + RE+ K++ EEK E E + E E + + K +R+ +
Sbjct: 390 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK------IREQE 443
Query: 650 GNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQT 709
+ +M RQ + H + E+KR E E K H Q
Sbjct: 444 EKIREQEKKMWRQE-EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE 502
Query: 710 QSSPFARGNVFGEPPT----ELQIKQQE--LYKNFLRFQIEEKKQREEAE-RERLRIAEE 762
+ V+ + E +I++QE +++ + + +E+ REE + E+ +I EE
Sbjct: 503 EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEE 562
Query: 763 -----------KEERRLAEQRARI--QQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQK 809
++E ++ EQ ++ Q+E EQE+KR+++EE+ K EE IR EE+ +
Sbjct: 563 EKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQ 622
Query: 810 EAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDS 869
E E K +E+EEK Q + E++ +GE+ + M + +Q + + ++ +
Sbjct: 623 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE---EKMQEQEETMWRQEEKIRE 679
Query: 870 IIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIME-LSEMRKQLRSEERRLQERLLH 928
+ + R Q + ++ ++ +EEK E + E +++R +E ++ E+ +
Sbjct: 680 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 739
Query: 929 MDSDDE 934
+ +E
Sbjct: 740 LRQQEE 745
Score = 75.9 bits (185), Expect = 2e-13
Identities = 68/343 (19%), Positives = 150/343 (43%), Gaps = 38/343 (11%)
Query: 584 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGA 643
E+K + ++ + +E + +Q + REE +++E+EE E K+ + +
Sbjct: 443 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWR--------- 493
Query: 644 PLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAE--NLEDAAN 701
+MH Q + + + + + + + + + E+
Sbjct: 494 -----------QKEKMHEQE-EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR 541
Query: 702 KSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAE 761
+ + + + ++ E K+QE R + + ++Q E+ R+ +I E
Sbjct: 542 EQEEMWREEEKMHEQEKIWEEE------KRQEQEDKMWRQEEKIREQEEKVWRQEEKIRE 595
Query: 762 EKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEK 821
++E+R+ E++ Q+E EQE+K +++EE+ + EE IR EE +E E K E+EEK
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Query: 822 YNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMS 881
Q + E++ + + + +R+ + + KI + + + + + E M
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEE--KMWEQEEKMC 713
Query: 882 RAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQE 924
Q + ++ ++R +EEK + E +LR +E ++QE
Sbjct: 714 E-QEEKMQEQEEKMRRQEEK------MWEQEVRLRQQEEKMQE 749
Score = 69.3 bits (168), Expect = 2e-11
Identities = 79/337 (23%), Positives = 150/337 (44%), Gaps = 21/337 (6%)
Query: 726 ELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEK 785
+ Q+++ EL+ N L Q EEK R+E E+++ EEK + + E++ R Q+E EQE+
Sbjct: 282 QAQVEENELW-NRLNQQQEEKMWRQE---EKIQEWEEKIQEQ--EEKIREQEEKIREQEE 335
Query: 786 KREKEEEQRLKNEEHIRLAEERQKEAERKKK-------EEEEKYNLQLQHYCERDNLIGE 838
K ++EE + EE +R EE E E K + E+EEK Q + E++ I E
Sbjct: 336 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 395
Query: 839 ETKHMRQPSPIVPALQNK-IASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRA 897
+ M + I + + K++ + R Q + ++ ++
Sbjct: 396 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR 455
Query: 898 EEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQA 957
+EEK + ++ E K+ EE QE +H + E R+KE+ M + + +
Sbjct: 456 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIH---EQEEIWRQKEK--MHEQEEKIRKQEE 510
Query: 958 PVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLREQ 1017
V RQ K + + + + E R E + + M+ + + H +I ++ +EQ
Sbjct: 511 KVWRQEEKIREQE--EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQ 568
Query: 1018 QKRLNRIKMQEGAKVDLDAIPSAKVREQRMPRDDTSD 1054
+ ++ R + + + + K+REQ R + +
Sbjct: 569 EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE 605
Score = 60.5 bits (145), Expect = 1e-08
Identities = 77/380 (20%), Positives = 160/380 (42%), Gaps = 51/380 (13%)
Query: 562 NTVGQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEAL--------QQQIREREERRK 613
NT+ ELK + ++ + E + + +++ + L QQQ++ +
Sbjct: 212 NTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG 271
Query: 614 KEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDAR 673
KE + AKL+A++ W NR+++Q + + +
Sbjct: 272 KELQS---VSAKLQAQVEENELW--------------------NRLNQQQEEKMWRQEEK 308
Query: 674 TYEDKRAVVSLDPNLATSNAE--NLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQ 731
E + + + + + E+ + M + R E +Q
Sbjct: 309 IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 368
Query: 732 QELYKNFLRFQIEEKKQREEA----ERERLRIAEEK--EERRLAEQRARIQQEYEEEQEK 785
+E+ ++ EEK +R+E + E++R EEK E+ ++ EQ + Q+E + +++
Sbjct: 369 EEMM-----WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 423
Query: 786 KREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQ 845
KR+++E + + EE IR EE+ +E E+K +EEK + Q + E+ + RQ
Sbjct: 424 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK--IHEQEKIREEEKRQEQEEMWRQ 481
Query: 846 PSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVI 905
I Q +I + ++ + IR E + R Q + ++ ++R +EEK
Sbjct: 482 EEKIHE--QEEIWRQKEKMHEQEEKIRK--QEEKVWR-QEEKIREQEEKIREQEEKMWRQ 536
Query: 906 MELSEMRKQLRSEERRLQER 925
E ++++ EE ++ E+
Sbjct: 537 EEKIREQEEMWREEEKMHEQ 556
Score = 48.9 bits (115), Expect = 3e-05
Identities = 76/385 (19%), Positives = 160/385 (41%), Gaps = 49/385 (12%)
Query: 42 DEFIEEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGS 101
DE ++E+ A+L E +ES+ +++ K + E +K+L +P Q
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLL-------LPQQQLQAEAD 268
Query: 102 LGIDYGLSLPLGEDYERKKHKLKEELRQD--YRRYLTQERLKLERNKEYNQFLRGK-EES 158
LG++ + KL+ ++ ++ + R Q+ K+ R +E Q K +E
Sbjct: 269 ---------HLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 319
Query: 159 SEKFRQVE---KSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEEL 215
EK R+ E + E K +R ++ + + + + Q + E E R+ E E++
Sbjct: 320 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 379
Query: 216 LNQRRL---EEDRYRQLDD---EIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRF 269
Q + +E++ R+L++ E E + K+ EE K Q +K + +
Sbjct: 380 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 439
Query: 270 HRFNEDRVFDRRYHRPDQDPEVSEE----MDERFRYESDFDRRLSRVYTNDRMHRNKRGN 325
R E+++ ++ Q+ ++ E+ +E+ + + + R+ +++ + + R K
Sbjct: 440 -REQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKE-- 496
Query: 326 MPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRK 385
M + I + ++ E K E + + E I+ ++
Sbjct: 497 --KMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKM----------WRQEEKIREQE 544
Query: 386 EKYRLELLEQMAEQQRNKRREKDLE 410
E +R E E+M EQ++ EK E
Sbjct: 545 EMWREE--EKMHEQEKIWEEEKRQE 567
Score = 38.9 bits (89), Expect = 0.030
Identities = 50/294 (17%), Positives = 126/294 (42%), Gaps = 18/294 (6%)
Query: 117 ERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQVEK--STEPKSQ 174
E +K + +EE+ + + QE + ++ K + Q + +++ + +RQ EK E K +
Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527
Query: 175 RNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIE 234
++ + + + + Q + E + ++ + E +E ++ +E++ R+ ++++
Sbjct: 528 EQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVW 587
Query: 235 LRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEE 294
+ +I + EE K Q K + + R E+++ ++ +Q+ ++ E+
Sbjct: 588 RQEEKI--REQEE------KRQEQEEKMWKQEEKI-REQEEKIQEQEEKIREQEEKIREQ 638
Query: 295 MDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDN 354
+ E + ++ + + + M E + I + +I E K
Sbjct: 639 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE---EKIREQEKKIREQEEKIREQE 695
Query: 355 ETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKRREKD 408
E + + M E E +Q ++EK R + E+M EQ+ R++++
Sbjct: 696 EMMQEQEEKMWEQEEKMC---EQEEKMQEQEEKMRRQ-EEKMWEQEVRLRQQEE 745
Score = 32.3 bits (72), Expect = 2.8
Identities = 33/173 (19%), Positives = 79/173 (45%), Gaps = 22/173 (12%)
Query: 783 QEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKH 842
Q+KK ++ E+ K + + L R + + KE+ K +LQ + I K
Sbjct: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 246
Query: 843 MRQ---------PSPIVPALQNKIASKLQRPPSVDSIIRSFIHESS----MSRAQSPPVP 889
+++ P + A + + +LQ SV + +++ + E+ +++ Q +
Sbjct: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQ---SVSAKLQAQVEENELWNRLNQQQEEKMW 303
Query: 890 ARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKER 942
++ +++ EEK + E +++R +E +++E+ M +E+ K+E+
Sbjct: 304 RQEEKIQEWEEK------IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK 350
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 78.2 bits (191), Expect = 4e-14
Identities = 121/539 (22%), Positives = 225/539 (41%), Gaps = 97/539 (17%)
Query: 584 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREE--KEEYEAK-LEAEMRTY--NPWGK 638
E P + SL +Q E E K+E+ E +E YE + E ++Y N W
Sbjct: 120 EFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDW-- 177
Query: 639 GGGGAPLRDAKGNLITDLNRMHRQN------------IDAYHNPDARTYEDKRAVVSLDP 686
RDA+ N D + + ++ +++ V+SL
Sbjct: 178 -------RDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKN 230
Query: 687 NLATSNA----ENLEDAANKSSGHMQTQS-----SPFARGNVFGEPPTELQIKQ-QELYK 736
+S E E +++ S H + + + R + E ++ +Q +++
Sbjct: 231 GQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIAD 290
Query: 737 NFLRFQIEEK------KQREEAERERLRIAEEKEERRLAEQRARIQQEYEE--------E 782
R + EEK ++RE ERER+R +EE+R AE+R RI++E + +
Sbjct: 291 ERARIEAEEKAAAQERERREAEERERMR----EEEKRAAEERQRIKEEEKRAAEERQRIK 346
Query: 783 QEKKREKEEEQRLKNEEHIRLAEERQK---EAERKKKEEEEKYNLQLQHYCERDNLIGEE 839
+E+KR EE QR+K EE R AEERQ+ E E K K EE+K N QL EE
Sbjct: 347 EEEKRAAEERQRIKEEEK-RAAEERQRARAEEEEKAKVEEQKRNKQL-----------EE 394
Query: 840 TKHMRQPSPIV-PALQNKIASKL--QRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLR 896
KH Q + I ++ KI K ++ D + + + + + V A++ +L+
Sbjct: 395 KKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTK--VQAKREKLQ 452
Query: 897 AEE---EKKNVIMELSEMRKQLRSEERRLQER---LLHMDSDDEIPIRKKERNPMDIFDM 950
++ +K+ + E + K+ + E + +R + S + + K ++ + F
Sbjct: 453 EDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSR 512
Query: 951 ARHRLQAPVRR-------QSPKGLDAATFQ----NVHDFNELKDRDSETRVDLKFMYLDP 999
R + ++ K L+ + +F +LK + E ++L+ L
Sbjct: 513 PGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELE--ELKK 570
Query: 1000 PRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAI----PSAKVREQRMPRDDTSD 1054
R+ ++++ R+Q++ +++ +E + + I A + Q+MP D SD
Sbjct: 571 KREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSD 629
Score = 60.8 bits (146), Expect = 7e-09
Identities = 105/604 (17%), Positives = 237/604 (39%), Gaps = 86/604 (14%)
Query: 598 QEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLN 657
+ A +++ R R+ER ++++EE+ + + E+ N + D + T
Sbjct: 36 EAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQN---------SVPDEEAKTTTTNT 86
Query: 658 RMHRQNIDAYHNPDARTYE--DKRAVVSL-----------DPNLATSNAENLEDAANKSS 704
++ + A+ AR E KR +L D +L+ + D A +
Sbjct: 87 QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENET 146
Query: 705 GHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLR--IAEE 762
+ +S E T + Q+ +++ + E+K++ EE E + R I E
Sbjct: 147 TEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGEN 206
Query: 763 KEERRLAEQRARIQQE------YEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK 816
+ E + E+ Q+E + + K+EE+R + + I + + E E K++
Sbjct: 207 QVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEI--SHHEKMEEEDKER 264
Query: 817 EEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIH 876
E E+ L+ + ER+ + E+ K + + A + A + +R + + R +
Sbjct: 265 AEAERARLEAE---ERERIKAEQDKKIADERARIEAEEKAAAQERERREAEE---RERMR 318
Query: 877 ESSMSRAQSPPVPARKNQLRAEEEKKNVIME---LSEMRKQLRSEERRLQERLLHMDSDD 933
E RA ++ + RA EE++ + E +E R++++ EE+R E +++
Sbjct: 319 EEE-KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEE 377
Query: 934 EIPIRKKERNPMDIFDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLK 993
E + +E+ + +H +Q ++K E +++ K
Sbjct: 378 EEKAKVEEQKRNKQLEEKKHAMQE---------------------TKIKGEKVEQKIEGK 416
Query: 994 FMYLDPPRDH--HTLEIQQQALLREQQKRLNRIKMQEGAKV-DLDAIPSAKVREQRMPRD 1050
++ ++ T +++Q + + + R K+QE + I K+++ + P++
Sbjct: 417 WVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKE 476
Query: 1051 D-----------------TSDFLKNSLLESDSAFIGAYGETYPAIEDDVLPPPSQLPSAR 1093
+ +F+ + L +++ F G ++ P +
Sbjct: 477 EVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRL 536
Query: 1094 E---RRRNKWKGLDIDSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRRLNEFHNKPIN 1150
E RRR + + + + + L L+ + + +V EE RR E ++ +
Sbjct: 537 EELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLR 596
Query: 1151 TDDE 1154
++E
Sbjct: 597 EEEE 600
Score = 56.6 bits (135), Expect = 1e-07
Identities = 78/343 (22%), Positives = 149/343 (43%), Gaps = 37/343 (10%)
Query: 585 DKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEA-KLEAEMRTYNPWGKGGGGA 643
++ K + Q + E ++Q+I + KK +E+K + K + E + G
Sbjct: 393 EEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEK----------GT 442
Query: 644 PLRDAKGNLITDLNRMHRQNI-DAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANK 702
++ + L D ++ I D D E+ ++ + ++N E +K
Sbjct: 443 KVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHK 502
Query: 703 SSGHMQTQSSPFARGNVF-----GEPPTELQIKQQELYKNFLRFQIEE----KKQREEAE 753
T S P R +V G P E + +EL + + EE K++++EA
Sbjct: 503 LKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAA 562
Query: 754 RERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNE---EHIRLAEERQKE 810
E + +++EERR + +++ EE K RE+EE++RLK E AE+RQK
Sbjct: 563 LELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKM 622
Query: 811 AERKKKEEEEKY--------NLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQ 862
E ++++ + +L+++ E N +++ ++ S A+ +KI S+L+
Sbjct: 623 PEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVK--STHQAAIVSKIDSRLE 680
Query: 863 RPPSVDSIIRSFIHESSMSRAQSPPVPAR-KNQLRAEEEKKNV 904
+ S +S + + A PVPA +++ EK NV
Sbjct: 681 QYTSAIEGTKS--AKPTKPAASDLPVPAEGVRNIKSMWEKGNV 721
Score = 48.5 bits (114), Expect = 4e-05
Identities = 82/438 (18%), Positives = 184/438 (42%), Gaps = 74/438 (16%)
Query: 558 QPVVNTVGQNELKITSDQV------------INSGLIFEDKPKPSKQSLQ-----SYQEA 600
+P ++G+N++++ ++ + +G I ++PK ++ Q S+ E
Sbjct: 197 KPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEK 256
Query: 601 LQQQIREREE--RRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNR 658
++++ +ER E R + E EE+E +A+ + ++ + A ++ + + R
Sbjct: 257 MEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERER 316
Query: 659 MHRQNIDAYHNPDARTYEDKRAV-----VSLDPNLATSNAENLEDAANKSSGHMQTQSSP 713
M + A E+KRA + + A + +++ +++ Q +
Sbjct: 317 MREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARA- 375
Query: 714 FARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEK------EERR 767
E + ++++Q+ K Q+EEKK + + + E+K E++
Sbjct: 376 --------EEEEKAKVEEQKRNK-----QLEEKKHAMQETKIKGEKVEQKIEGKWVNEKK 422
Query: 768 LAE---QRARIQQEYEEEQEK---KREKEEEQR--LKNEEHIRLAEERQKEAERKKKEEE 819
E Q A ++++ EE+ K KREK +E + K EE + +E+ K+ +++ KEE
Sbjct: 423 AQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEE---IKDEKIKK-DKEPKEEV 478
Query: 820 EKYNLQLQHYCERDNLIGE----ETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFI 875
+ + + + + E + GE + KH + + + P V++ R +
Sbjct: 479 KSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKR--L 536
Query: 876 HESSMSRAQSPPVPARK------------NQLRAEEEKKNVIMELSEMRKQLRSEERRLQ 923
E R ++ K +L+ + E++ ++E E R++ +R+L+
Sbjct: 537 EELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLR 596
Query: 924 ERLLHMDSDDEIPIRKKE 941
E +EI R+ E
Sbjct: 597 EEEEKRRLKEEIERRRAE 614
Score = 40.8 bits (94), Expect = 0.008
Identities = 72/406 (17%), Positives = 157/406 (38%), Gaps = 51/406 (12%)
Query: 42 DEFIEEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGS 101
DE +K EDK E++ +E + + K ++ KI A+ +
Sbjct: 249 DEISHHEKME-EEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAA----- 302
Query: 102 LGIDYGLSLPLGEDYERKKHKLKEELRQDYRRYLTQ-ERLKLERNKEYNQFLRGKEESS- 159
++ ER++ + +E +R++ +R + +R+K E + + R KEE
Sbjct: 303 -----------AQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKR 351
Query: 160 -----EKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEE 214
++ ++ EK + QR + + + E + ++ E E+
Sbjct: 352 AAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQ 411
Query: 215 LLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGIS-NLKHQRFAS------KAGIPDR 267
+ + + E + ++ D+++ ++KK EE G K ++ K I D
Sbjct: 412 KIEGKWVNEKKAQE--DKLQTA---VLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDE 466
Query: 268 RFHRFNEDR-----VFDRRYHRPDQDPEVSEEMDERFRY-ESDFDRRLSRVYTNDRMHRN 321
+ + E + DR+ + + E M + ++ E+ F R R +
Sbjct: 467 KIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVD-----T 521
Query: 322 KRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDR-EL 380
K P G +E+ R E++ + E K Q+ + E+R ++
Sbjct: 522 KEAEGAPQVEAGKRLEELRRRRGETESE---EFEKLKQKQQEAALELEELKKKREERRKV 578
Query: 381 IQRRKEKYRLELLEQMAEQQRNKRREKDLELRVAASGAQDPEKSPD 426
++ +++ + E ++ ++ KRR K+ R A A+ +K P+
Sbjct: 579 LEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPE 624
Score = 38.5 bits (88), Expect = 0.040
Identities = 51/275 (18%), Positives = 108/275 (39%), Gaps = 26/275 (9%)
Query: 155 KEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEE 214
+E+ S++ EK E +R + +++ + +I+ + + + E
Sbjct: 244 REQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAA 303
Query: 215 LLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNE 274
+RR E+R R ++E K+A EE +K + K +R+ + E
Sbjct: 304 QERERREAEERERMREEE---------KRAAEE--RQRIKEE---EKRAAEERQRIKEEE 349
Query: 275 DRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGD 334
R + R +++ +EE +R R E + ++ + RNK+ +E
Sbjct: 350 KRAAEERQRIKEEEKRAAEER-QRARAEEEEKAKV------EEQKRNKQ-----LEEKKH 397
Query: 335 VIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLE 394
++++ I+ E K K A +D G E +Q ++EK + +
Sbjct: 398 AMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPT 457
Query: 395 QMAEQQRNKRREKDLELRVAASGAQDPEKSPDRLK 429
E+ ++++ +KD E + D +K +K
Sbjct: 458 FKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVK 492
Score = 37.7 bits (86), Expect = 0.067
Identities = 72/348 (20%), Positives = 135/348 (38%), Gaps = 45/348 (12%)
Query: 126 ELRQDYRRYLTQE-RLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVK 184
E R++ RR +E RL+ ER Y + +EE++ + R+ + + ++ ++ +GQV
Sbjct: 5 ERRRELRRQKREEMRLEAER-IAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQV- 62
Query: 185 PDLTSQIQTSCENS---------------EGPRKDVLTPSEAYEELLNQRRLEEDRYRQ- 228
T Q++ + +NS EG + A E Q+RL+E RQ
Sbjct: 63 ---TDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQK 119
Query: 229 ------LDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRY 282
D + L +RR+ E + K ++ S+ + + E + Y
Sbjct: 120 EFDPTITDASLSLPSRRMQNDTAENE--TTEKEEKSESR-----QERYEIEETETVTKSY 172
Query: 283 HRPD-QDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNI 341
+ D +D E +++ D+ E + + + N ++ + + V+ N
Sbjct: 173 QKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGEN-QVEVMVEEKTTESQEETVVMSLKNG 231
Query: 342 RISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQR 401
+ISS E P E + D S M E+ + + E+ RLE E+ +
Sbjct: 232 QISSEE----PKQEEEREQGSDEISHHEKM----EEEDKERAEAERARLEAEERERIKAE 283
Query: 402 NKRREKDLELRVAASGAQDPEKSPDRLKQFSVAPRHFEEMIPPERPRI 449
++ D R+ A ++ R + R E+ ER RI
Sbjct: 284 QDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRI 331
Score = 35.0 bits (79), Expect = 0.44
Identities = 39/175 (22%), Positives = 78/175 (44%), Gaps = 28/175 (16%)
Query: 750 EEAERERLRIAEEKEERRLAEQRARIQQEYEEEQE-----KKREKEEEQRLKNEEHI--R 802
++ ER R +++EE RL +R Q+ ++E+E ++R ++E R K EE +
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 803 LAEERQKEAERKKKEEEEK---YNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIAS 859
+ ++ + A+ +EE K N Q++ +E + + + Q ++
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEG--------DDEAAFLERLARREERRQKRLQE 113
Query: 860 KLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQ 914
L+R D I ++S+S +P+R+ Q E + E SE R++
Sbjct: 114 ALERQKEFDPTIT----DASLS------LPSRRMQNDTAENETTEKEEKSESRQE 158
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 76.6 bits (187), Expect = 1e-13
Identities = 53/226 (23%), Positives = 115/226 (50%), Gaps = 11/226 (4%)
Query: 726 ELQIKQQE---LYKNFLRFQIEEKKQREEA----ERERLRIAEEK--EERRLAEQRARIQ 776
E +I++QE + + ++ EEK +R+E + E++R EEK E+ ++ EQ + Q
Sbjct: 308 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 367
Query: 777 QEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLI 836
+E + +++KR+++E + + EE IR EE+ +E E +E+EEK Q + E++ +
Sbjct: 368 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEM 427
Query: 837 GEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLR 896
E+ + MR+ + + KI + ++ + +++ E M +
Sbjct: 428 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE--QEEKMGEQEGKMCEQEAKMQE 485
Query: 897 AEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKER 942
EE+ + ++ E K++R +E +++E+ M +E ++E+
Sbjct: 486 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 531
Score = 75.9 bits (185), Expect = 2e-13
Identities = 52/208 (25%), Positives = 112/208 (53%), Gaps = 6/208 (2%)
Query: 730 KQQELYKNFLRFQIEEKKQREEAE--RERLRIAEEKEERRLAEQRARIQQEYEEEQEKKR 787
+Q+E + + + +EK+Q +EA+ R+ +I E++E+ R E+ + Q+E EQE+K
Sbjct: 361 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 420
Query: 788 EKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPS 847
++EE+ + EE +R EE+ +E E+K +E+EEK Q + E++ +GE+ M +
Sbjct: 421 WEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQE 480
Query: 848 PIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIME 907
+ + K+ + ++ + IR + R Q + ++ ++ +EEK E
Sbjct: 481 AKMQEQEEKMRRQEEKIREQEKKIR---EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 537
Query: 908 -LSEMRKQLRSEERRLQERLLHMDSDDE 934
+ E +++R +E +++E+ + + +E
Sbjct: 538 KMQEQEEKMRRQEEKMREQEVRLRQQEE 565
Score = 75.5 bits (184), Expect = 3e-13
Identities = 79/346 (22%), Positives = 148/346 (42%), Gaps = 68/346 (19%)
Query: 584 EDKPKPSKQSLQSYQEALQQQ---IREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGG 640
E+K ++ +Q +E +Q+Q IRE+EE+ +++ E E E K+ + W K
Sbjct: 287 EEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM--WEKEE 344
Query: 641 GGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAA 700
L + +MH Q R E+KR E + +
Sbjct: 345 KIRELEE----------KMHEQE-------KIREQEEKR-----------QEEEKIRE-- 374
Query: 701 NKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIA 760
Q K+QE R Q E+ +++EE RE+ +
Sbjct: 375 ---------------------------QEKRQEQEAKMWR-QEEKIREQEEKIREQEEMM 406
Query: 761 EEKEERRLAEQRARIQQEYEE--EQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEE 818
+E+EE+ + EQ ++ ++ EE EQE+K ++EE+ + E+ IR EE+ +E E +E+
Sbjct: 407 QEQEEK-MGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 465
Query: 819 EEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHES 878
EEK Q CE++ + E+ + MR+ + + KI + ++ + +++ E
Sbjct: 466 EEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE--QEE 523
Query: 879 SMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQE 924
M + + EE+ + ++ E +LR +E ++QE
Sbjct: 524 KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 70.5 bits (171), Expect = 9e-12
Identities = 60/232 (25%), Positives = 117/232 (50%), Gaps = 20/232 (8%)
Query: 726 ELQIKQQELYKNFLRFQIEEKKQREE---AERERLRIAEEKEERRLAEQRARIQQEYEEE 782
+ Q+++ EL+ N L Q EEK R+E ERE +I E++E+ R E++ R Q+E E
Sbjct: 270 QAQVEENELW-NRLNQQQEEKMWRQEEKIQEREE-KIQEQEEKIREQEEKMRRQEEMMWE 327
Query: 783 QEKKREKEEEQRLKNEEHIRLAEERQ------KEAERKKKEEE-----EKYNLQLQHYCE 831
+E+K ++EE + EE IR EE+ +E E K++EEE EK Q
Sbjct: 328 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 387
Query: 832 RDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPAR 891
++ I E+ + +R+ ++ + K+ + ++ + ++ + R Q + +
Sbjct: 388 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQ---EQEEKMRRQEEKIREQ 444
Query: 892 KNQLRAEEEKKNVIME-LSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKER 942
+ ++R +EEK E + E +++ +E ++ E+ M +E R++E+
Sbjct: 445 EKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEK 496
Score = 55.8 bits (133), Expect = 2e-07
Identities = 88/419 (21%), Positives = 170/419 (40%), Gaps = 49/419 (11%)
Query: 554 HQLAQPVVNTVGQNELKITSDQVINSGLIFED-------KPKPSKQSLQSYQEALQQQIR 606
H P V T + T + IN+G E P+ +++ +QEAL++++
Sbjct: 59 HPQTNPSVGTAASD----TKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELE 114
Query: 607 EREERRKKEREEKEEYEA----------KLEAEMRT-----YNPWGKGGGGAPLRDAKGN 651
+ + + +K E + +LE E R ++ W G L A
Sbjct: 115 AQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAG---ELEQALSA 171
Query: 652 LITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQS 711
+ T + R + DA + E R ++ D L NA+ E S + Q
Sbjct: 172 VATQKKKADRYIEELTKERDALSLELYRNTIT-DEELKEKNAKLQEKLQLVESEKSEIQL 230
Query: 712 S------PFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEE 765
+ R + P +LQ + L K + K Q + E E +++E
Sbjct: 231 NVKELKRKLERAKLL-LPQQQLQAEADHLGKELQ--SVSAKLQAQVEENELWNRLNQQQE 287
Query: 766 RRLAEQRARIQQEYE--EEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYN 823
++ Q +IQ+ E +EQE+K ++EE+ + EE + EE+ + E E+EEK
Sbjct: 288 EKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 347
Query: 824 LQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRA 883
+ E++ + +E K + + + +K+ R + IR + R
Sbjct: 348 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ---EEKIR---EQEEKIRE 401
Query: 884 QSPPVPARKNQLRAEEEKK-NVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKE 941
Q + ++ ++ +EEK E+ E +++R +E +++E+ + +E IR++E
Sbjct: 402 QEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEE-KIREQE 459
Score = 46.2 bits (108), Expect = 2e-04
Identities = 73/382 (19%), Positives = 158/382 (41%), Gaps = 49/382 (12%)
Query: 42 DEFIEEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGS 101
DE ++E+ A+L E +ES+ +++ K + E +K+L +P Q
Sbjct: 204 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLL-------LPQQQLQAEAD 256
Query: 102 LGIDYGLSLPLGEDYERKKHKLKEELRQD--YRRYLTQERLKLERNKEYNQFLRGK-EES 158
LG++ + KL+ ++ ++ + R Q+ K+ R +E Q K +E
Sbjct: 257 ---------HLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQ 307
Query: 159 SEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQ 218
EK R+ E+ K +R ++ + + + + Q + E E R E E++ Q
Sbjct: 308 EEKIREQEE----KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR-------ELEEKMHEQ 356
Query: 219 RRL-EEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRV 277
++ E++ RQ +++I + +R ++A ++ Q + + E+++
Sbjct: 357 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR---EQEEMMQEQEEKM 413
Query: 278 FDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPM-----EHD 332
++ +Q+ E+ E+ ++ R E + ++ + R + M E +
Sbjct: 414 GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQE 473
Query: 333 GDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKY---- 388
G + EQ ++ E K E + + + E E++Q ++EK
Sbjct: 474 GKMCEQ-EAKMQEQEEKMRRQEEKIREQEKKIREQEEKI---REQEEMMQEQEEKMWEQE 529
Query: 389 --RLELLEQMAEQQRNKRREKD 408
E E+M EQ+ RR+++
Sbjct: 530 EKMCEQEEKMQEQEEKMRRQEE 551
Score = 35.8 bits (81), Expect = 0.26
Identities = 42/250 (16%), Positives = 111/250 (44%), Gaps = 36/250 (14%)
Query: 783 QEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKH 842
Q+KK ++ E+ K + + L R + + KE+ K +LQ + I K
Sbjct: 175 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 234
Query: 843 MRQ---------PSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKN 893
+++ P + A + + +LQ SV + +++ + E+ + N
Sbjct: 235 LKRKLERAKLLLPQQQLQAEADHLGKELQ---SVSAKLQAQVEENELW-----------N 280
Query: 894 QLRAEEEKKNVIME--LSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMA 951
+L ++E+K E + E ++++ +E +++E+ M +E+ K+E+ M
Sbjct: 281 RLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEK-------MR 333
Query: 952 RHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQ 1011
R + + + L+ + +H+ ++++++ + + + K + ++ +Q+
Sbjct: 334 RQEEMMWEKEEKIRELE----EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389
Query: 1012 ALLREQQKRL 1021
+REQ++++
Sbjct: 390 EKIREQEEKI 399
Score = 31.6 bits (70), Expect = 4.8
Identities = 38/238 (15%), Positives = 103/238 (43%), Gaps = 22/238 (9%)
Query: 115 DYERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQVE---KSTEP 171
+ E K H+ +E++R+ + +E+++ + ++ + ++E EK R+ E + E
Sbjct: 348 ELEEKMHE-QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE--EKIREQEEKIREQEE 404
Query: 172 KSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDD 231
Q ++ +G+ + + Q + E E R+ EE + R +E + R+ ++
Sbjct: 405 MMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQ--------EEKI---REQEKKIREQEE 453
Query: 232 EIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEV 291
+I ++++ E++G K +K + + R E+++ ++ +Q+ ++
Sbjct: 454 KIR-EQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR-QEEKIREQEKKIREQEEKI 511
Query: 292 SEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENK 349
E+ + E + ++ + + + M E + + + +R+ E K
Sbjct: 512 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE---EKMREQEVRLRQQEEK 566
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 76.3 bits (186), Expect = 2e-13
Identities = 81/357 (22%), Positives = 161/357 (45%), Gaps = 40/357 (11%)
Query: 584 EDKPKPSKQSLQSYQEALQQQIREREERRKK-EREEKEEYEAKL---EAEMRTYNP-WG- 637
E+K + ++++ +E QQ R E++ K E+E+ +E E K+ E ++R WG
Sbjct: 412 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ 471
Query: 638 --KGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAEN 695
K +R+ + + +M Q + + +D+R
Sbjct: 472 EKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERL-------------RE 518
Query: 696 LEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIK----QQELYKNFLRFQIEEKKQREE 751
E+ + Q + + E T+ Q K Q+E + R + EKK REE
Sbjct: 519 KEERMREQKKMWQQEEK------MREEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 572
Query: 752 AERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEA 811
E R E++E+ + E++ R Q+E EQE+K +++EE+ + EE + EE K
Sbjct: 573 EEMMR----EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
Query: 812 ERKKK--EEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDS 869
E+++ E+EEK Q + E++ + E+ + MR+ + + K+ + ++ +
Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEE 688
Query: 870 IIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERL 926
+R + R Q + ++ ++ +EEK E+ E +++R ++ ++QERL
Sbjct: 689 KMRE---QEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERL 742
Score = 74.7 bits (182), Expect = 5e-13
Identities = 88/381 (23%), Positives = 163/381 (42%), Gaps = 46/381 (12%)
Query: 587 PKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLR 646
P+ K++ +QEAL+++I ++ + +K E E L + G G +
Sbjct: 69 PEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGES-K 127
Query: 647 DAKGNL------ITDLNRMHRQNIDAYHNPDARTYED---KRAVVSLD--------PNLA 689
D G L +L R + +H R E+ +R +SL+ L
Sbjct: 128 DLAGRLHHSWHFAGELQRA-LSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELK 186
Query: 690 TSNAENLEDA--ANKSSGHMQTQSSPFARG---NVFGEPPTELQIKQQELYKNFLRFQIE 744
NAE E A +Q R F P + Q+E+++ + +
Sbjct: 187 KKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQ 246
Query: 745 EKKQREEAE---RERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHI 801
EKK R++ E R+ R+ E++ + R E++ R Q++ EQEK+ +E+E+ L+ ++ +
Sbjct: 247 EKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKEL-REQEKELREQKKL 305
Query: 802 RLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKL 861
R EE+ +E E K E+EEK Q + ++ + E+ K MR+ + K+ +
Sbjct: 306 REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ-------EQKMRDQE 358
Query: 862 QRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERR 921
+R D +R E M + ++ +EEK + E K++R EE
Sbjct: 359 ERMWEQDERLRE--KEERM---------REQEKMWEQEEKMQEEERIREREKKMREEEET 407
Query: 922 LQERLLHMDSDDEIPIRKKER 942
++E+ M +E ++E+
Sbjct: 408 MREQEEKMQKQEENMWEQEEK 428
Score = 71.6 bits (174), Expect = 4e-12
Identities = 53/223 (23%), Positives = 114/223 (51%), Gaps = 14/223 (6%)
Query: 722 EPPTELQIKQQELYKNFLRFQIEEKKQREEAER-----ERLRIAEEK---EERRLAEQRA 773
E +++ +++++++ R + +E K RE+ E+ +RLR E++ +E+ L EQ+
Sbjct: 245 EQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK 304
Query: 774 -RIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCER 832
R Q+E +EQE+K ++EE+ + EE + EER E E++ +E+E+K Q + E+
Sbjct: 305 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364
Query: 833 DNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARK 892
D + E+ + MR+ + + K+Q + + E R Q + ++
Sbjct: 365 DERLREKEERMREQEKMW-----EQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 419
Query: 893 NQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEI 935
+ +EEK+ L E +++L +E+ ++ + +++I
Sbjct: 420 ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 462
Score = 70.1 bits (170), Expect = 1e-11
Identities = 72/376 (19%), Positives = 177/376 (47%), Gaps = 40/376 (10%)
Query: 584 EDKPKPSKQSLQSYQEALQQQ---IREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGG 640
E + + +Q ++ +E + +Q +RE+EER + E+E+ E E K++ E R K
Sbjct: 344 EKQMREQEQKMRDQEERMWEQDERLREKEERMR-EQEKMWEQEEKMQEEERIREREKK-- 400
Query: 641 GGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAA 700
+R+ + + +M +Q + + + + ++ +R + + E+
Sbjct: 401 ----MREEEETMREQEEKMQKQEENMWEQEE-KEWQQQRLPEQKEKLWEQEKMQEQEEKI 455
Query: 701 NKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAER-----E 755
+ ++ Q + + +++ ++ ++++ + + +E+K ++ ER E
Sbjct: 456 WEQEEKIRDQEEMWGQEKKMWRQE-KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDE 514
Query: 756 RLRIAEEK--EERRLAEQRARIQQEYE-EEQEKK------REKEEEQRLKNEEHIRLAEE 806
RLR EE+ E++++ +Q ++++E + +EQEKK + +EEE+ + E+ +R EE
Sbjct: 515 RLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 574
Query: 807 RQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPS 866
+E E K +E+EEK Q + E++ + E+ + M + + + K+Q
Sbjct: 575 MMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE--KMWEQEEEDKMQEQEE 632
Query: 867 VDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERL 926
+ + + Q + ++ ++R +EEK + E ++++ +E +++E+
Sbjct: 633 M------MWEQEEKMQEQEEKMWEQEEKMREQEEK------MREQEEKMQGQEEKMREQE 680
Query: 927 LHMDSDDEIPIRKKER 942
M +E ++E+
Sbjct: 681 EKMQGQEEKMREQEEK 696
Score = 59.7 bits (143), Expect = 2e-08
Identities = 61/274 (22%), Positives = 129/274 (47%), Gaps = 31/274 (11%)
Query: 584 EDKPKPSKQSLQSYQEALQQQ---IREREERRKKER-----EEKEEYEAKL-EAEMRTYN 634
E+K + +Q + +E + +Q +RE+EER ++++ EEK E K E E +T++
Sbjct: 492 EEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWD 551
Query: 635 PWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAE 694
K +R+ + + + M R+ + + + E + + + + +
Sbjct: 552 QEEKMREEERMREREKKMREE-EEMMREQEEKMQEQEEKMREQEEKMWEQEEKM-----Q 605
Query: 695 NLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAER 754
E+ + M Q E ++Q +++ +++ + Q +E+K E+ E+
Sbjct: 606 EQEEKMWEQEEKMWEQ-----------EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654
Query: 755 ERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERK 814
R E++E+ R E++ + Q+E EQE+K + +EE+ + EE +R EE+ E K
Sbjct: 655 MR----EQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEK 710
Query: 815 KKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSP 848
+EEK Q + E++ I ++ + M++ P
Sbjct: 711 MWGQEEKMWGQ-EEMREKEERIRDQKEKMQERLP 743
Score = 40.0 bits (92), Expect = 0.014
Identities = 79/431 (18%), Positives = 166/431 (38%), Gaps = 22/431 (5%)
Query: 42 DEFIEEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGS 101
D +IEE EL + E K +A+L E ++ S K I N ++ +
Sbjct: 158 DRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAES-EKSEIQLNVKELKRK 216
Query: 102 LG-IDYGLSLPLGEDYERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGK-EESS 159
L + L + + + +EELR+ ++ QE K+ R +E + GK E
Sbjct: 217 LERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEE-KMWRQEERLREQEGKMREQE 275
Query: 160 EKFRQVEK---------STEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKD---VLT 207
EK R+ EK + K R +K + + + + Q + E E R+ +
Sbjct: 276 EKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWR 335
Query: 208 PSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNL--KHQRFASKAGIP 265
E E Q R +E + R ++ + ++ R+ +K + + ++ + I
Sbjct: 336 QEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIR 395
Query: 266 DRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGN 325
+R E+ + + + E E +E+ + + +++ ++M +
Sbjct: 396 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI 455
Query: 326 MPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDR--ELIQR 383
E D E + + E ++ ++ E+R E +R
Sbjct: 456 WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515
Query: 384 RKEK-YRLELLEQMAEQQRNKRREKDLELRVAASGAQDPE-KSPDRLKQFSVAPRHFEEM 441
+EK R+ ++M +Q+ R EK + + + Q+ + + +R+++ R EEM
Sbjct: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 575
Query: 442 IPPERPRIAFQ 452
+ + ++ Q
Sbjct: 576 MREQEEKMQEQ 586
Score = 37.0 bits (84), Expect = 0.11
Identities = 52/320 (16%), Positives = 127/320 (39%), Gaps = 37/320 (11%)
Query: 115 DYERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQ 174
+ E++ + ++ELR+ + +E+++ + K + Q + +E+ + +RQ E+ E + Q
Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 346
Query: 175 --RNKKPIGQVKPDLTSQIQTSCENSEGPR--------KDVLTPSEAYEELLNQRRLEED 224
++ + + + Q + E E R ++ + E E + R EE+
Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEE 406
Query: 225 RYRQLDDEIELRNRRIIKKANEEVGISNLKHQR----------------FASKAGIPDRR 268
R+ +++++ + + ++ +E L Q+ + + I D+
Sbjct: 407 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 466
Query: 269 FHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPP 328
E +++ + R +D +E R + + +D+ R++ D R K M
Sbjct: 467 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE-ERMWEQDERLREKEERMRE 525
Query: 329 MEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKY 388
+ E+ + E + ++ K ++ +RE R +E+
Sbjct: 526 QKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERM----------REREKKMREEEEM 575
Query: 389 RLELLEQMAEQQRNKRREKD 408
E E+M EQ+ R +++
Sbjct: 576 MREQEEKMQEQEEKMREQEE 595
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 73.9 bits (180), Expect = 8e-13
Identities = 82/374 (21%), Positives = 171/374 (45%), Gaps = 32/374 (8%)
Query: 584 EDKPKPSKQSLQSYQEALQQQ---IREREERRKKEREE---KEEYEAKLEAEMRTYNP-- 635
E+K ++ +Q ++E +Q+Q IRE+EE+ +++ E+ +EE + E +MR
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358
Query: 636 WGKGGGGAPLRDA---KGNLITDLN-RMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATS 691
W K L + K I +L +MH Q + + + E+++ +
Sbjct: 359 WEKEEKMRRLEEMMWEKEEKIRELEEKMHEQ--EKIREQEEKRQEEEKIREQEKRQEQEA 416
Query: 692 NAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREE 751
E+ + ++ Q R +++ +++ + + Q E+ +++EE
Sbjct: 417 KMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 476
Query: 752 AERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEA 811
R++ ++ E+E+ R E++ Q+E +QE+K ++EE+ + EE IR EE+ +E
Sbjct: 477 IWRQKEKM-HEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQ 535
Query: 812 ERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPI------VPALQNKIASKLQRPP 865
E K +E+EE Q + E++ + E+ K RQ I + + KI + ++
Sbjct: 536 EEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIW 595
Query: 866 SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIME--------LSEMRKQLRS 917
+ IR + M + Q + ++ ++ +EEK E + E +LR
Sbjct: 596 EQEEKIR---EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 652
Query: 918 EERRLQERLLHMDS 931
+E ++QE H+++
Sbjct: 653 QEEKMQEHQEHLEA 666
Score = 63.9 bits (154), Expect = 9e-10
Identities = 82/335 (24%), Positives = 150/335 (44%), Gaps = 55/335 (16%)
Query: 726 ELQIKQQELYKNFLRFQIEEKKQREEA---------ERERLRIAEEKEERRLAEQRARIQ 776
+ Q+++ EL+ N L Q EEK R+E + + +I E++E+ R E++ R Q
Sbjct: 282 QAQVEENELW-NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ 340
Query: 777 QEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLI 836
+E E+E+K ++EE + EE +R EE E E K +E EEK + E++ +
Sbjct: 341 EEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH-------EQEKIR 393
Query: 837 GEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLR 896
+E K + KI + +R + R + R Q + ++ ++
Sbjct: 394 EQEEKRQE---------EEKIREQEKRQEQEAKMWR----QEEKIREQEEKIREQEKKMW 440
Query: 897 AEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQ 956
+EEK + ++ E K+ EE QE + + E R+KE+ H Q
Sbjct: 441 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR---EQEEIWRQKEK---------MHE-Q 487
Query: 957 APVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYL----DPPRDHHTLEIQQQA 1012
+R+Q K + +HD E K R+ E ++ + + + R+ +Q+
Sbjct: 488 EKIRKQEEKVWRQE--EKMHD-QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEE 544
Query: 1013 LLREQQKRL--NRIKMQEGAKVDLDAIPSAKVREQ 1045
+++EQ++++ KMQE K+ K+REQ
Sbjct: 545 MMQEQEEKMGEQEEKMQEQEKMRRQ---EEKIREQ 576
Score = 53.1 bits (126), Expect = 2e-06
Identities = 71/386 (18%), Positives = 168/386 (43%), Gaps = 46/386 (11%)
Query: 42 DEFIEEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGS 101
DE ++E+ A+L E +ES+ +++ K + E +K+L +P Q
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLL-------LPQQQLQAEAD 268
Query: 102 LGIDYGLSLPLGEDYERKKHKLKEELRQD--YRRYLTQERLKLERNKEYNQFLRGK-EES 158
LG++ + KL+ ++ ++ + R Q+ K+ R +E Q K +E
Sbjct: 269 ---------HLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 319
Query: 159 SEKFRQVE---KSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRK--DVLTPSEAYE 213
EK R+ E + E K +R ++ + + + + Q + E E R+ +++ E
Sbjct: 320 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKI 379
Query: 214 ELLNQRRLEEDRYRQLD----DEIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRF 269
L ++ E+++ R+ + +E ++R + ++ ++ K + K +++
Sbjct: 380 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM 439
Query: 270 HRFNEDRVFDRRYHRPDQDPEVSEEM---DERFRYESDFDRRLSRVYTNDRMHRNKR--- 323
R E+++ ++ R ++ + EEM +E+ R + + R+ +++ +++ + +
Sbjct: 440 WR-QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVW 498
Query: 324 GNMPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQR 383
M + I + ++ E K E + + E E++Q
Sbjct: 499 RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKI----------REQEEMMQE 548
Query: 384 RKEKYRLELLEQMAEQQRNKRREKDL 409
++EK E E+M EQ++ +R+E+ +
Sbjct: 549 QEEKMG-EQEEKMQEQEKMRRQEEKI 573
Score = 44.3 bits (103), Expect = 7e-04
Identities = 65/338 (19%), Positives = 132/338 (39%), Gaps = 35/338 (10%)
Query: 114 EDYERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFR-QVEKSTEPK 172
E+ R++ ++ E + RR E + E+ ++ + L K EK R Q EK E +
Sbjct: 348 EEKMRRQEEMMWEKEEKMRRL---EEMMWEKEEKIRE-LEEKMHEQEKIREQEEKRQEEE 403
Query: 173 SQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDE 232
R ++ + + + Q + E E R+ E++ Q ++ E+ RQ +E
Sbjct: 404 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE 463
Query: 233 IELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVS 292
+ + +I + EE+ + K + ++ R E++V+ + DQ+ ++
Sbjct: 464 MWRQEEKI--REQEEI---------WRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIR 512
Query: 293 EEMDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEH-----DGDVIEQSNIR----- 342
E+ ++ +R E + ++ + R + M E + + EQ +R
Sbjct: 513 EQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEK 572
Query: 343 ISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKY------RLELLEQM 396
I E K E + + + E E++Q ++EK E E+M
Sbjct: 573 IREQEEKIREQKEKIREQEEKIWEQEEKIR---EQEEMMQEQEEKMWEQEEKMCEQEEKM 629
Query: 397 AEQQRNKRREKDLELRVAASGAQDPEKSPDRLKQFSVA 434
EQ+ RR+++ Q EK + + A
Sbjct: 630 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 667
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 72.8 bits (177), Expect = 2e-12
Identities = 67/365 (18%), Positives = 163/365 (44%), Gaps = 16/365 (4%)
Query: 584 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKE--EYEAKLEAEMRTYNPWGKGGG 641
+D+ K+ QE + +Q+ + E +K + +EK+ + E K++ E R K
Sbjct: 402 QDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKK--- 458
Query: 642 GAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAAN 701
+R+ + + +M +Q + + + + ++ +R + + E+
Sbjct: 459 ---MREEEETMREQEEKMQKQEENMWEQEE-KEWQQQRLPEQKEKLWEQEKMQEQEEKIW 514
Query: 702 KSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAE 761
+ ++ Q + + +++ ++ ++++ + + +E+K ++ ER + E
Sbjct: 515 EQEEKIRDQEEMWGQEKKMWRQE-KMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQE 573
Query: 762 EKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEK 821
++++ E++ R ++E E+EKK +EEE + EE ++ EE+ +E E K E+EEK
Sbjct: 574 QEKKTWDQEEKMR-EEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEK 632
Query: 822 YNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKI--ASKLQRPPSVDSIIRSFIHESS 879
Q + E++ + E+ + M + + P + K+ K+Q + +
Sbjct: 633 MQEQEEKMWEQEEKMWEQEEKMWEQQRL-PEQKEKLWEHEKMQEQEKMQEQEEKIWEQEK 691
Query: 880 MSRAQSPPVPARKNQ--LRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPI 937
M + +Q +R EE + ++ E + +R +E ++QE+ M +E
Sbjct: 692 MEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMW 751
Query: 938 RKKER 942
++E+
Sbjct: 752 EQEEK 756
Score = 71.6 bits (174), Expect = 4e-12
Identities = 56/230 (24%), Positives = 111/230 (48%), Gaps = 16/230 (6%)
Query: 723 PPTELQIKQQELYKNFLRFQIEEKKQREEAER-----ERLR-----IAEEKEERRLAEQR 772
P + Q+E+++ + +EKK R++ E+ ERLR + E++E+ E+R
Sbjct: 263 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKR 322
Query: 773 ARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCER 832
R Q++ EQEK+ +++E R + EE ++ EE+ E E K +E+EEK Q + E+
Sbjct: 323 LREQEKELREQEKELREQKELR-EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 381
Query: 833 DNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARK 892
+ + E+ + MR + ++ K +R + + E + + ++
Sbjct: 382 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK-----MWEQVEKMREEKKMQEQE 436
Query: 893 NQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKER 942
+ R +EEK + E K++R EE ++E+ M +E ++E+
Sbjct: 437 KKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 486
Score = 70.5 bits (171), Expect = 9e-12
Identities = 84/374 (22%), Positives = 158/374 (42%), Gaps = 42/374 (11%)
Query: 584 EDKPKPSKQSLQSYQEALQQQ--IREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGG 641
E K + ++ + +E +Q++ IRERE++ ++E E E E K++ + N W
Sbjct: 429 EKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE--NMW----- 481
Query: 642 GAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAAN 701
+ R+ Q + + E+K E + D
Sbjct: 482 ------EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK----------IWEQEEKIRDQEE 525
Query: 702 K--SSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRF----QIEEKK--QREEAE 753
M Q + + E +++ ++Q+++ R Q +EKK +EE
Sbjct: 526 MWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKM 585
Query: 754 RERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAER 813
RE R+ E +++ R E+ R Q+E +EQE+K +++EE+ + EE ++ EE+ E E
Sbjct: 586 REEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE 645
Query: 814 KKKEEEEKYNLQLQHYCERDNL-----IGEETKHMRQPSPIVPALQNKIASKLQRPPSVD 868
K E+EEK Q + +++ L + E+ K Q I Q K+ K Q
Sbjct: 646 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWE--QEKMEKKTQEQEKKT 703
Query: 869 SIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIME-LSEMRKQLRSEERRLQERLL 927
E SM R + + + +R +EEK E + E +++ +E ++ E+
Sbjct: 704 WDQEKMREEESM-REREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEE 762
Query: 928 HMDSDDEIPIRKKE 941
M +P +K++
Sbjct: 763 KMWEQQRLPEQKEK 776
Score = 65.9 bits (159), Expect = 2e-10
Identities = 81/448 (18%), Positives = 192/448 (42%), Gaps = 38/448 (8%)
Query: 584 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGA 643
++K ++ L+ +E +Q+Q + E+ +K RE++E+ + E W +
Sbjct: 333 QEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE------RLWEQ---EK 383
Query: 644 PLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKS 703
+R+ + + RM Q+ + + R E ++ ++ + E
Sbjct: 384 QMREQEQKMRDQEERMWEQD-ERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQ 442
Query: 704 SGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEK 763
MQ + R E ++ +++++ K Q E ++EE E ++ R+ E+K
Sbjct: 443 EEKMQEEERIREREKKMREEEETMREQEEKMQK-----QEENMWEQEEKEWQQQRLPEQK 497
Query: 764 EERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYN 823
E+ E+ +++ E++EK R++EE + +E +E+ +E E + E+EEK
Sbjct: 498 EKLWEQEKMQEQEEKIWEQEEKIRDQEE---MWGQEKKMWRQEKMREQEDQMWEQEEKMR 554
Query: 824 LQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRA 883
Q Q +++ + ++T+ + + K++ + + E M R
Sbjct: 555 DQEQKMWDQEERMEKKTQEQEKKT-------WDQEEKMREEERMREREKKMREEEEMMRE 607
Query: 884 QSPPVPARKNQLRAEEEKK-NVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKER 942
Q + ++ +++ +EEK ++ E +++ +E ++ E+ M +P +K++
Sbjct: 608 QEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEK- 666
Query: 943 NPMDIFDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRD 1002
+++ + + Q ++ Q K + + E K D E K + R+
Sbjct: 667 ----LWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQE-----KMREEESMRE 717
Query: 1003 HHTLEIQQQALLREQQKRL--NRIKMQE 1028
+++ ++REQ++++ KMQE
Sbjct: 718 REKKMREEEEMMREQEEKMQEQEEKMQE 745
Score = 64.3 bits (155), Expect = 7e-10
Identities = 71/326 (21%), Positives = 144/326 (44%), Gaps = 59/326 (18%)
Query: 733 ELYKNFL--------RFQIEEKKQREEAERERLRIAEEKEERRLAE--------QRARIQ 776
ELY+N + +++EK E+E+ +++ ++ +R+L Q +Q
Sbjct: 212 ELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQ 271
Query: 777 QEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLI 836
+E ++E+ RE+E++ R K EE + EER +E E K +E+EEK Q + E++ +
Sbjct: 272 EEMWRQEEELREQEKKIR-KQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKEL 330
Query: 837 GEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLR 896
E+ K +R+ + + + Q + ++ ++R
Sbjct: 331 REQEKELREQ-------------------------KELREQEEQMQEQEEKMWEQEEKMR 365
Query: 897 AEEEKK-NVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDM----A 951
+EEK L E KQ+R +E++++++ M DE +R+KE + M
Sbjct: 366 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE-RLREKEERMREQEKMWEQVE 424
Query: 952 RHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPR---------D 1002
+ R + ++ Q K D + + + +++R+ + R + + M + +
Sbjct: 425 KMREEKKMQEQEKKTRDQE--EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 482
Query: 1003 HHTLEIQQQALLREQQKRLNRIKMQE 1028
E QQQ L +++K + KMQE
Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQE 508
Score = 64.3 bits (155), Expect = 7e-10
Identities = 70/364 (19%), Positives = 157/364 (43%), Gaps = 37/364 (10%)
Query: 584 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGA 643
E+K + +Q + +E ++++ +E+E++ + E+ E E E E +
Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKK------------ 597
Query: 644 PLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKS 703
+R+ + + +M Q + + + +E + + + + E E +
Sbjct: 598 -MREEEEMMREQEEKMQEQE-EKMQEQEEKMWEQEEKMQEQEEKMW----EQEEKMWEQE 651
Query: 704 SGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAER----ERLRI 759
+ Q P + ++ + Q K QE + + EKK +E+ ++ E++R
Sbjct: 652 EKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMR- 710
Query: 760 AEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEE- 818
E+E R E++ R ++E EQE+K +++EE+ + EE + EE+ E E K E+
Sbjct: 711 --EEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQ 768
Query: 819 ---EEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFI 875
E+K L + I E+ + MR + + K+ + ++ + + +
Sbjct: 769 RLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEE--KMWG 826
Query: 876 HESSMSRAQSPPVPARKNQLRAEEEKKNVIME-----LSEMRKQLRSEERRLQERLLHMD 930
E M Q + ++ ++ +EEK M+ + E +++R +E +++E+ M
Sbjct: 827 QEEKM-WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMR 885
Query: 931 SDDE 934
+E
Sbjct: 886 GQEE 889
Score = 62.0 bits (149), Expect = 3e-09
Identities = 79/381 (20%), Positives = 163/381 (42%), Gaps = 66/381 (17%)
Query: 595 QSYQEALQQQI-REREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLI 653
Q LQ+++ R+ EE R++E++ +++ E E R LR+ +G +
Sbjct: 264 QVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEER-------------LREQEGKMR 310
Query: 654 TDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSP 713
+M RQ + R E ++ + + L ++ + + +
Sbjct: 311 EQEEKMWRQ--------EKRLREQEKELREQEKELREQ-----KELREQEEQMQEQEEKM 357
Query: 714 FARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAER-----ERLRIAEEK----- 763
+ + E ++ +++ L++ + + +E+K R++ ER ERLR EE+
Sbjct: 358 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 417
Query: 764 ----------EERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEH-IRLAEERQKEAE 812
EE+++ EQ + + + E+ QE++R +E E++++ EE +R EE+ ++ E
Sbjct: 418 KMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 477
Query: 813 RKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIR 872
E+EEK Q Q E+ + E+ K Q I + KI + + + R
Sbjct: 478 ENMWEQEEK-EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ-EEKIRDQEEMWGQEKKMWR 535
Query: 873 SFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRS-----------EERR 921
R Q + ++ ++R +E+K E E + Q + EE R
Sbjct: 536 -----QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEER 590
Query: 922 LQERLLHMDSDDEIPIRKKER 942
++ER M ++E+ ++E+
Sbjct: 591 MREREKKMREEEEMMREQEEK 611
Score = 49.7 bits (117), Expect = 2e-05
Identities = 52/245 (21%), Positives = 111/245 (45%), Gaps = 25/245 (10%)
Query: 591 KQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKG 650
+Q L +E L + + +E+ + +E+EEK + K+E +T K +R+ +
Sbjct: 657 QQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEK--KTQEQEKKTWDQEKMREEES 714
Query: 651 NLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQ 710
+ + + R+ + + + E + + + + E E + + Q
Sbjct: 715 --MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMW----EQEEKMWEQEEKMWEQQ 768
Query: 711 SSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAER-----ERLRIAEEK-- 763
P + ++ E +Q+++++ + + +E+K R + E+ E++R EEK
Sbjct: 769 RLPEQKEKLWEH---EKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMW 825
Query: 764 --EERRLAEQRARIQQE-----YEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK 816
EE+ ++ QE EE+ E+K + +EE+ + EE +R EE+ +E E K +
Sbjct: 826 GQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMR 885
Query: 817 EEEEK 821
+EEK
Sbjct: 886 GQEEK 890
Score = 46.2 bits (108), Expect = 2e-04
Identities = 57/302 (18%), Positives = 129/302 (42%), Gaps = 50/302 (16%)
Query: 584 EDKPKPSKQSLQSYQEALQQQ---IREREERRKKEREEKEEYEAKL-EAEMRTYNPWGKG 639
E K + ++ ++ +E +Q+Q ++E+EE+ ++ E+ +E E K+ E E + + K
Sbjct: 595 EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM 654
Query: 640 GGGAPLRDAKGNL-----ITDLNRMHRQNIDAYHNP--DARTYEDKRAVVSLDPNLATSN 692
L + K L + + +M Q + + +T E ++ + +
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEES 714
Query: 693 AENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKK----Q 748
E + M+ Q E ++Q +++E+++ + +E+K Q
Sbjct: 715 MREREKKMREEEEMMREQEEKMQ------EQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQ 768
Query: 749 REEAERERL----------RIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNE 798
R ++E+L +I E++E+ R E++ R Q+E QE+K +EE+ E
Sbjct: 769 RLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQE 828
Query: 799 EHI-------------------RLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEE 839
E + ++ E+ Q + E+ +++EE+ + + + + + G+E
Sbjct: 829 EKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQE 888
Query: 840 TK 841
K
Sbjct: 889 EK 890
Score = 38.5 bits (88), Expect = 0.040
Identities = 67/393 (17%), Positives = 156/393 (39%), Gaps = 35/393 (8%)
Query: 45 IEEQKARLAEDKAELESDPPYMEMKGKL---SAKLSENSKILISMAKENIPPNSQQTRGS 101
+ EQ+ L E K E + E + K+ K+ E + + +E + +Q R
Sbjct: 330 LREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQ-EERLWEQEKQMR-- 386
Query: 102 LGIDYGLSLPLGEDYERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEK 161
+ E+K +E + + R +E E+ K + Q + +EE +K
Sbjct: 387 -------------EQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREE--KK 431
Query: 162 FRQVEKSTEPKSQR--NKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQR 219
++ EK T + ++ ++ I + + + + +T E E +K E E+ Q+
Sbjct: 432 MQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ 491
Query: 220 RLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFD 279
RL E + + + E I + E++ + + + + + + R ED++++
Sbjct: 492 RLPEQKEKLWEQEKMQEQEEKIWEQEEKI---RDQEEMWGQEKKMWRQEKMREQEDQMWE 548
Query: 280 RRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQS 339
+ DQ+ ++ ++ + + + +++ R R M + +++ +
Sbjct: 549 QEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 608
Query: 340 NIRISSAENKSAP------DNETSKSANQDTCSPFAGMLFGGEDRELIQRR--KEKYRLE 391
++ E K + E ++ ++ E++ Q+R ++K +L
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 668
Query: 392 LLEQMAEQQR-NKRREKDLELRVAASGAQDPEK 423
E+M EQ++ ++ EK E Q+ EK
Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK 701
Score = 38.1 bits (87), Expect = 0.052
Identities = 49/305 (16%), Positives = 129/305 (42%), Gaps = 16/305 (5%)
Query: 115 DYERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQ 174
+ E++ + ++ELR+ +E+++ + K + Q + +E+ + +RQ E+ E + Q
Sbjct: 325 EQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 384
Query: 175 --RNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDE 232
++ + + + Q + E E R+ E E++ +++++E + D E
Sbjct: 385 MREQEQKMRDQEERMWEQDERLREKEERMREQE-KMWEQVEKMREEKKMQEQEKKTRDQE 443
Query: 233 IELRNRRII-----KKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQ 287
+++ I K EE + + + + + ++ + + R+ +++ +Q
Sbjct: 444 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503
Query: 288 DPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAE 347
E +E +E+ + + R ++ ++ K M D + + ++ E
Sbjct: 504 --EKMQEQEEKIWEQEEKIRDQEEMWGQEK----KMWRQEKMREQEDQMWEQEEKMRDQE 557
Query: 348 NKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKRREK 407
K E + Q+ + E ++ R++K R E E+M +Q K +E+
Sbjct: 558 QKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREE--EEMMREQEEKMQEQ 615
Query: 408 DLELR 412
+ +++
Sbjct: 616 EEKMQ 620
Score = 35.4 bits (80), Expect = 0.33
Identities = 56/334 (16%), Positives = 140/334 (41%), Gaps = 38/334 (11%)
Query: 114 EDYERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKS 173
E+ +++ L EL YR +T E LK ++N E + L E + + K + K
Sbjct: 200 EELTKERDALSLEL---YRNTITNEELK-KKNAELQEKLPLAESEKSEIQLNVKELKRKL 255
Query: 174 QRNKKPIGQVKPD-LTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDE 232
+R K + QV+ + L ++ E K + E + R +E + R+ +++
Sbjct: 256 ERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEK 315
Query: 233 IELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVS 292
+ + +R+ ++ E L+ Q + + +++ R E+++ ++ +Q+ ++
Sbjct: 316 MWRQEKRLREQEKE------LREQ----EKELREQKELREQEEQMQEQEEKMWEQEEKMR 365
Query: 293 EEMDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAP 352
E+ ++ +R E R++ ++ R + M E + + + + R+ E +
Sbjct: 366 EQEEKMWRQEE-------RLWEQEKQMREQEQKMRDQE---ERMWEQDERLREKEERMRE 415
Query: 353 DNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKRREKDLELR 412
+ + + E++++ ++ K+ E E+M E++R + REK +
Sbjct: 416 QEKMWEQVEKMR-----------EEKKMQEQEKKTRDQE--EKMQEEERIREREKKMREE 462
Query: 413 VAASGAQDPEKSPDRLKQFSVAPRHFEEMIPPER 446
Q+ + + + +++ PE+
Sbjct: 463 EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 496
Score = 34.7 bits (78), Expect = 0.57
Identities = 49/298 (16%), Positives = 112/298 (37%), Gaps = 13/298 (4%)
Query: 115 DYERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQVEK--STEPK 172
+ E K + ++ LR+ + QE+ E+ + Q + +E+ + + Q EK E K
Sbjct: 311 EQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEK 370
Query: 173 SQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDE 232
R ++ + + + + Q Q + E + E E + Q ++ E
Sbjct: 371 MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE--------- 421
Query: 233 IELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVS 292
++ R KK E+ + + ++ + I +R E+ + + + E
Sbjct: 422 -QVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 480
Query: 293 EEMDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAP 352
E +E+ + + +++ ++M + E D E +
Sbjct: 481 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 540
Query: 353 DNETSKSANQDTCSPFAGMLFGGEDR-ELIQRRKEKYRLELLEQMAEQQRNKRREKDL 409
+ E ++ ++ E+R E + +EK + E+M E++R + REK +
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKM 598
Score = 33.5 bits (75), Expect = 1.3
Identities = 52/303 (17%), Positives = 119/303 (39%), Gaps = 31/303 (10%)
Query: 115 DYERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQ 174
+ E K K +E + + + Q+RL ++ K + Q +E EK + E+ + +
Sbjct: 468 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ--EKMQEQEEKIWEQEEKIRDQEE 525
Query: 175 ---RNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEE----DRYR 227
+ KK Q K + Q E E R + E + + + +E D+
Sbjct: 526 MWGQEKKMWRQEK--MREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEE 583
Query: 228 QLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQ 287
++ +E +R R KK EE + + ++ + E+++ ++ +Q
Sbjct: 584 KMREEERMRERE--KKMREEEEMMREQEEKMQEQ------------EEKMQEQEEKMWEQ 629
Query: 288 DPEVSEEMDERFRYESDFDRRLSRVYTNDRM--HRNKRGNMPPMEHDGDVIEQSNIRISS 345
+ ++ E+ ++ + E + +++ R+ + K M+ + EQ
Sbjct: 630 EEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQ 689
Query: 346 AENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKRR 405
+ + + K+ +Q+ M +RE R +E+ E E+M EQ+ +
Sbjct: 690 EKMEKKTQEQEKKTWDQEKMREEESM----REREKKMREEEEMMREQEEKMQEQEEKMQE 745
Query: 406 EKD 408
+++
Sbjct: 746 QEE 748
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 72.8 bits (177), Expect = 2e-12
Identities = 67/344 (19%), Positives = 155/344 (45%), Gaps = 29/344 (8%)
Query: 604 QIREREERRKKEREEKEEYEAKL-EAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQ 662
Q+RE+E + +++ + E E ++ E E + G+ +R+ +G + ++ Q
Sbjct: 116 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ------VREQEGQVREQEGQVREQ 169
Query: 663 NIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGE 722
+ + E + V + + + E Q Q G
Sbjct: 170 E-GQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGE---- 224
Query: 723 PPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEK----EERRLAEQRARIQQE 778
E Q+++QE Q+++++++ + + E++R EE+ EE+ ++ ++Q+
Sbjct: 225 --QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK 282
Query: 779 YEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGE 838
+ EQE++ ++EEQ + EE +R EE+ +E E + +E+EE+ Q + E+ + E
Sbjct: 283 EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE 342
Query: 839 ETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAE 898
+ + M + + ++ + ++ + +R + R Q + ++ Q+R +
Sbjct: 343 QKEQMWKQ-------EEQMGEQEEQMQKQEEQVRK---QEEQMRKQEEQMRKQEEQMRKQ 392
Query: 899 EEKKNVIME-LSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKE 941
EE+ E + E ++Q+R +E ++ E+ M +E +KE
Sbjct: 393 EEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 60.1 bits (144), Expect = 1e-08
Identities = 51/266 (19%), Positives = 120/266 (45%), Gaps = 48/266 (18%)
Query: 584 EDKPKPSKQSLQSYQEAL---QQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGG 640
E++ ++ +Q +E + ++Q+R++EE+ ++ E+ ++ E +++ +
Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQE---------- 254
Query: 641 GGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAA 700
+M +Q + ++++ + + E+
Sbjct: 255 ----------------EQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQM 298
Query: 701 NKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEK-KQREEAERERLRI 759
+ M+ Q E Q+++QE +R Q E+ KQ E+ ++ ++
Sbjct: 299 REQEEQMREQ---------------EEQMREQE---EQMREQEEQMGKQEEQMWEQKEQM 340
Query: 760 AEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEE 819
E+KE+ E++ Q+E ++QE++ K+EEQ K EE +R EE+ ++ E + E++
Sbjct: 341 WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQK 400
Query: 820 EKYNLQLQHYCERDNLIGEETKHMRQ 845
E+ Q + E++ +GE+ + MR+
Sbjct: 401 EQMGEQKEQMREQEEQMGEQKEQMRK 426
Score = 51.2 bits (121), Expect = 6e-06
Identities = 64/415 (15%), Positives = 167/415 (40%), Gaps = 13/415 (3%)
Query: 742 QIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEE-H 800
+++E+ Q E E+ +++ ++ +R+L + + QE + +++ + +E+E +++ +E
Sbjct: 15 ELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQ 74
Query: 801 IRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASK 860
+R E + +E E + +E+E + Q E++ + E+ +R+ V + ++ +
Sbjct: 75 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 134
Query: 861 LQRPPSVDSIIR----SFIHESSMSRAQSPPVPARKNQLRAEE----EKKNVIME----L 908
+ + +R + R Q V ++ Q+R +E E++ + E +
Sbjct: 135 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQM 194
Query: 909 SEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSPKGLD 968
E Q+ +E ++ E+ M +E ++E+ M Q + + + +
Sbjct: 195 GEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQE 254
Query: 969 AATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQE 1028
+ E +++ E + ++ T E ++Q +E+Q R +M+E
Sbjct: 255 EQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMRE 314
Query: 1029 GAKVDLDAIPSAKVREQRMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIEDDVLPPPSQ 1088
+ + +E++M + + + +G E E+ V Q
Sbjct: 315 QEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQ 374
Query: 1089 LPSARERRRNKWKGLDIDSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRRLNE 1143
+ E+ R + + + + + + + +E +E+MR+ E
Sbjct: 375 MRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
Score = 50.8 bits (120), Expect = 8e-06
Identities = 51/310 (16%), Positives = 130/310 (41%), Gaps = 32/310 (10%)
Query: 724 PTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQ 783
P E Q+++QE + ++Q + + ++ E++ + R E + R Q+ EQ
Sbjct: 49 PQEGQVREQE---------GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 99
Query: 784 EKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHM 843
E + ++E Q + E +R E + +E E + +E+E + Q E++ + E+ +
Sbjct: 100 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 159
Query: 844 RQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKN 903
R+ V + ++ + + + +R E M + + EE+ +
Sbjct: 160 REQEGQVREQEGQVREQEGQVREQEGQVRE--QEGQMGEQEGQMGEQEEQMGEQEEQMQK 217
Query: 904 VIMELSEMRKQLRSEERRLQERLLHMDSDD------EIPIRKKERNPMDIFDMARHRLQA 957
++ E +Q+R +E ++ E+ + + E +RK+E + + R + +
Sbjct: 218 QEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQ 277
Query: 958 PVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLREQ 1017
++++ + T + E +++ E ++ +Q+ +REQ
Sbjct: 278 MLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMR---------------EQEEQMREQ 322
Query: 1018 QKRLNRIKMQ 1027
++++ + + Q
Sbjct: 323 EEQMGKQEEQ 332
Score = 50.4 bits (119), Expect = 1e-05
Identities = 42/256 (16%), Positives = 111/256 (43%), Gaps = 54/256 (21%)
Query: 584 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGA 643
E++ ++ +Q +E Q++++EE+ +K+ E+ E E +
Sbjct: 233 EEQMGEQEEQVQKQEE----QVQKQEEQMRKQEEQMREQEEQ------------------ 270
Query: 644 PLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKS 703
+R+ + ++ + ++ R E++ E+ +
Sbjct: 271 -MREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQ--------------MREQEEQMREQ 315
Query: 704 SGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEK 763
M+ Q G+ ++ +++++++ Q+E+ ++ ++ E++
Sbjct: 316 EEQMREQEEQ------MGKQEEQMWEQKEQMWE-----------QKEQMWKQEEQMGEQE 358
Query: 764 EERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYN 823
E+ + E++ R Q+E +QE++ K+EEQ K EE + +E+ E + + +E+EE+
Sbjct: 359 EQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMG 418
Query: 824 LQLQHYCERDNLIGEE 839
Q + +++ +GE+
Sbjct: 419 EQKEQMRKQEEHMGEQ 434
Score = 49.7 bits (117), Expect = 2e-05
Identities = 53/311 (17%), Positives = 135/311 (43%), Gaps = 17/311 (5%)
Query: 725 TELQIKQQELYKNFLRFQI------EEKKQREEAERERLRIAEEKEERRLAEQRARIQQE 778
+E+Q+ +EL + +I + ++Q + + ++ E++ + R E + R Q+
Sbjct: 28 SEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 87
Query: 779 YEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGE 838
EQE + ++E Q + E +R E + +E E + +E+E + Q E++ + E
Sbjct: 88 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 147
Query: 839 ETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAE 898
+ +R+ V + ++ + + + +R + R Q + ++ Q+ +
Sbjct: 148 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVR---EQEGQVREQEGQMGEQEGQMGEQ 204
Query: 899 EEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQAP 958
EE ++ E +Q++ +E ++ E+ M +E ++E+ + + Q
Sbjct: 205 EE------QMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQ-- 256
Query: 959 VRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLREQQ 1018
+R+Q + + + LK ++ + + + R+ +Q+ +REQ+
Sbjct: 257 MRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQE 316
Query: 1019 KRLNRIKMQEG 1029
+++ + Q G
Sbjct: 317 EQMREQEEQMG 327
Score = 32.7 bits (73), Expect = 2.2
Identities = 62/337 (18%), Positives = 132/337 (39%), Gaps = 30/337 (8%)
Query: 135 LTQERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPI---GQVKPDLTSQI 191
+T E LK E+N E + L+ E + + K + K + +K P+ GQV+ + Q+
Sbjct: 4 ITNEELK-EKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVR-EQEGQV 61
Query: 192 QTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGIS 251
+ V E Q R +E + R+ + ++ + ++ +E +
Sbjct: 62 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV---REQEGQVR 118
Query: 252 NLKHQRFASKAGIPDRRFH-RFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLS 310
+ Q + + ++ R E +V ++ +Q+ +V E+ + E +
Sbjct: 119 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 178
Query: 311 RVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAG 370
+V + R + G M E +G + EQ ++ E + E +
Sbjct: 179 QVREQEGQVREQEGQMG--EQEGQMGEQEE-QMGEQEEQMQKQEEQMGEQEEQMRKQEEQ 235
Query: 371 MLFGGEDRELIQ-------------RRKEKYRLELLEQMAEQQRNKRREKDLELRVAASG 417
M GE E +Q R++E+ E EQM EQ+ ++K+ + +G
Sbjct: 236 M---GEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTG 292
Query: 418 AQDPE--KSPDRLKQFSVAPRHFEEMIPPERPRIAFQ 452
Q+ + + +++++ R EE + + ++ Q
Sbjct: 293 EQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQ 329
>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
sapiens]
Length = 1323
Score = 70.1 bits (170), Expect = 1e-11
Identities = 51/193 (26%), Positives = 91/193 (47%), Gaps = 23/193 (11%)
Query: 718 NVFGEPPTELQIK-QQELYKNFLRFQIEEKKQREEAERERL------------------- 757
N GEP + L + + L ++FLR Q+ K++ E R++L
Sbjct: 333 NDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQ 392
Query: 758 -RIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK 816
RI E+KE+RR E++ R ++E ++QE+++ + E++++ EE R AE Q+ ++ +
Sbjct: 393 KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLE 452
Query: 817 EEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIH 876
E+ + LQ Q ERD L+ +H RQ V + P + +
Sbjct: 453 EQRQAERLQRQLKQERDYLV--SLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEE 510
Query: 877 ESSMSRAQSPPVP 889
S ++R SP +P
Sbjct: 511 RSRLNRQSSPAMP 523
Score = 44.3 bits (103), Expect = 7e-04
Identities = 68/310 (21%), Positives = 121/310 (39%), Gaps = 47/310 (15%)
Query: 708 QTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERR 767
Q PF R + P E Q++ Q K+ + +++ +++E E E EE+EE
Sbjct: 282 QLMKHPFIR-----DQPNERQVRIQ--LKDHIDRTKKKRGEKDETEYEYSGSEEEEEEND 334
Query: 768 LAEQRA---------------RIQQEYEEEQEK-KREKEEEQRLKNEEHIR-LAEERQKE 810
E + R+Q +E E +R++ E+Q+ +NEEH R L ERQK
Sbjct: 335 SGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKR 394
Query: 811 AE-----RKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASK-LQRP 864
E R++ EE+++ +L+ ER+ E + R+ + + K L+
Sbjct: 395 IEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQ 454
Query: 865 PSVDSIIRSFIHES----SMSRAQSPPVPARKNQL------RAEEEKKNVIMELSEMRKQ 914
+ + R E S+ + P K L + EK E+ E +
Sbjct: 455 RQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEERSRL 514
Query: 915 LRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSP-------KGL 967
R + ++ + SD +P R + + + + PV Q P +G
Sbjct: 515 NRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKSQGP 574
Query: 968 DAATFQNVHD 977
Q+VH+
Sbjct: 575 ALTASQSVHE 584
Score = 32.3 bits (72), Expect = 2.8
Identities = 13/48 (27%), Positives = 29/48 (60%)
Query: 582 IFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAE 629
+ ++ K ++ + + +QQ RE+E R+++ERE++ YE ++ E
Sbjct: 387 LLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRRE 434
Score = 31.6 bits (70), Expect = 4.8
Identities = 90/434 (20%), Positives = 162/434 (37%), Gaps = 56/434 (12%)
Query: 377 DRELIQRRKEKYRLELLEQMAEQQRNKRREKDLEL-RVAASGAQDPEKSPDRLKQ---FS 432
++EL ++++ + R EQM ++ +R E + E R + E+ +LKQ +
Sbjct: 412 EKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYL 471
Query: 433 VAPRH-FEEMIPPERPRIAFQTPLPPLSAPSVPPIPSVHPVPSQNEDLRSGLSSALGEMV 491
V+ +H +E P E+ PL PS P ++ + RS L+ +
Sbjct: 472 VSLQHQRQEQRPVEK---------KPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSPAM 522
Query: 492 SPRIAPLPPPPLLPPLATNYRTPYDDAYYFYGSRNTFDPSLAYYGSGMMGVQPAAYVSAP 551
++A P LPP + ++ DP + + + + Q A ++
Sbjct: 523 PHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVA--VKSQGPALTASQ 580
Query: 552 VTHQLAQPVVNTVG-QNELKITSDQV----INSGLIFEDKPKPSKQSLQSYQEALQQQIR 606
H+ QP G Q L +TS +V NS E+ P P++
Sbjct: 581 SVHE--QPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTR--------------I 624
Query: 607 EREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDA 666
E+ +R R+E E+ K+ + +P +++ GN R+ Q I A
Sbjct: 625 EKFDRSSWLRQE-EDIPPKVPQRTTSISP------ALARKNSPGNGSALGPRLGSQPIRA 677
Query: 667 YHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTE 726
NPD R E + P TS+ + + S Q S P ++
Sbjct: 678 -SNPDLRRTEP----ILESPLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVR 732
Query: 727 LQIKQQ---ELYKNFLRFQIEEKKQ--REEAERERLRIAEEKEERRLAEQRARIQQ--EY 779
K + L + + EE + R + +A+E E R+ E +++ +Y
Sbjct: 733 ANSKSEGSPVLPHEPAKVKPEESRDITRPSRPADLTALAKELRELRIEETNRPMKKVTDY 792
Query: 780 EEEQEKKREKEEEQ 793
E+ EEE+
Sbjct: 793 SSSSEESESSEEEE 806
>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
sapiens]
Length = 1331
Score = 70.1 bits (170), Expect = 1e-11
Identities = 51/193 (26%), Positives = 91/193 (47%), Gaps = 23/193 (11%)
Query: 718 NVFGEPPTELQIK-QQELYKNFLRFQIEEKKQREEAERERL------------------- 757
N GEP + L + + L ++FLR Q+ K++ E R++L
Sbjct: 333 NDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQ 392
Query: 758 -RIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK 816
RI E+KE+RR E++ R ++E ++QE+++ + E++++ EE R AE Q+ ++ +
Sbjct: 393 KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLE 452
Query: 817 EEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIH 876
E+ + LQ Q ERD L+ +H RQ V + P + +
Sbjct: 453 EQRQAERLQRQLKQERDYLV--SLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEE 510
Query: 877 ESSMSRAQSPPVP 889
S ++R SP +P
Sbjct: 511 RSRLNRQSSPAMP 523
Score = 44.3 bits (103), Expect = 7e-04
Identities = 68/310 (21%), Positives = 121/310 (39%), Gaps = 47/310 (15%)
Query: 708 QTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERR 767
Q PF R + P E Q++ Q K+ + +++ +++E E E EE+EE
Sbjct: 282 QLMKHPFIR-----DQPNERQVRIQ--LKDHIDRTKKKRGEKDETEYEYSGSEEEEEEND 334
Query: 768 LAEQRA---------------RIQQEYEEEQEK-KREKEEEQRLKNEEHIR-LAEERQKE 810
E + R+Q +E E +R++ E+Q+ +NEEH R L ERQK
Sbjct: 335 SGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKR 394
Query: 811 AE-----RKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASK-LQRP 864
E R++ EE+++ +L+ ER+ E + R+ + + K L+
Sbjct: 395 IEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQ 454
Query: 865 PSVDSIIRSFIHES----SMSRAQSPPVPARKNQL------RAEEEKKNVIMELSEMRKQ 914
+ + R E S+ + P K L + EK E+ E +
Sbjct: 455 RQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEERSRL 514
Query: 915 LRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSP-------KGL 967
R + ++ + SD +P R + + + + PV Q P +G
Sbjct: 515 NRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKSQGP 574
Query: 968 DAATFQNVHD 977
Q+VH+
Sbjct: 575 ALTASQSVHE 584
Score = 32.3 bits (72), Expect = 2.8
Identities = 13/48 (27%), Positives = 29/48 (60%)
Query: 582 IFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAE 629
+ ++ K ++ + + +QQ RE+E R+++ERE++ YE ++ E
Sbjct: 387 LLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRRE 434
Score = 31.6 bits (70), Expect = 4.8
Identities = 82/431 (19%), Positives = 165/431 (38%), Gaps = 42/431 (9%)
Query: 377 DRELIQRRKEKYRLELLEQMAEQQRNKRREKDLEL-RVAASGAQDPEKSPDRLKQ---FS 432
++EL ++++ + R EQM ++ +R E + E R + E+ +LKQ +
Sbjct: 412 EKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYL 471
Query: 433 VAPRH-FEEMIPPERPRIAFQTPLPPLSAPSVPPIPSVHPVPSQNEDLRSGLSSALGEMV 491
V+ +H +E P E+ PL PS P ++ + RS L+ +
Sbjct: 472 VSLQHQRQEQRPVEK---------KPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSPAM 522
Query: 492 SPRIAPLPPPPLLPPLATNYRTPYDDAYYFYGSRNTFDPSLAYYGSGMMGVQPAAYVSAP 551
++A P LPP + ++ DP + + + + Q A ++
Sbjct: 523 PHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVA--VKSQGPALTASQ 580
Query: 552 VTHQLAQPVVNTVG-QNELKITSDQV----INSGLIFEDKPKPSKQSLQSYQEALQQQIR 606
H+ QP G Q L +TS +V NS E+ P P++ ++ + + +R
Sbjct: 581 SVHE--QPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTR--IEKFDRS--SWLR 634
Query: 607 EREERRKKEREEKEEYEAKLEAEMRTYNPWGKGG--GGAPLRDAKGNLITDLNRMHRQNI 664
+ E+ K + L + N G G P+R + +L R+
Sbjct: 635 QEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDL--------RRTE 686
Query: 665 DAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPP 724
+P RT + S + +S + + SS + +++ + G+ P
Sbjct: 687 PILESPLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPV-LPH 745
Query: 725 TELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQ--EYEEE 782
++K +E + ++ + + +A+E E R+ E +++ +Y
Sbjct: 746 EPAKVKPEE--SRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSS 803
Query: 783 QEKKREKEEEQ 793
E+ EEE+
Sbjct: 804 SEESESSEEEE 814
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 68.9 bits (167), Expect = 3e-11
Identities = 54/203 (26%), Positives = 97/203 (47%), Gaps = 31/203 (15%)
Query: 726 ELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQ--RARIQQEYEEEQ 783
E++ EL K EE+++ EE ERE + EE+EER+ E+ ++++E EE++
Sbjct: 2229 EMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKK 2288
Query: 784 EKKREKEEEQRLKNEEHIRLAEE--RQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETK 841
+KK+EK++E+ + EE EE ++E E EEEE+ + L+ +R+ I ++ K
Sbjct: 2289 KKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEK 2348
Query: 842 HMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIH-------------------ESSMSR 882
+ LQ + L+ V SI+R H +++
Sbjct: 2349 QFK--------LQEQRRKSLRGRERVLSILRGVPHGKGRAIRLGVLKSPLKKLMSTALEM 2400
Query: 883 AQSPPVPARKNQLRAEEEKKNVI 905
+ PVP + Q+ E++K V+
Sbjct: 2401 KEKTPVPVPEKQISWEDKKATVV 2423
Score = 58.5 bits (140), Expect = 4e-08
Identities = 60/286 (20%), Positives = 124/286 (43%), Gaps = 28/286 (9%)
Query: 565 GQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEK----E 620
GQ +L S ++I +P + L++ Q+ + + + +E K + ++ +
Sbjct: 2048 GQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVK 2107
Query: 621 EYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRA 680
E +E W + + L D ++ R+ N R +
Sbjct: 2108 ERRLSIEQSKLDIKEWD-------FSEKRSELTKDEKKLARKQ-RKLANKMRRMINKEEK 2159
Query: 681 VVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGN-------VFGEPPTELQIKQQE 733
+ + LA ++E + D + G + + PF + G+ P E Q +
Sbjct: 2160 MTEEESKLARKHSEVILDD-EEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVD 2218
Query: 734 LYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQ 793
++ F E + +E E++ +EE+EER E+R + EEE+ K+ E+ EE+
Sbjct: 2219 EVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEK 2278
Query: 794 RLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEE 839
+++ EE E+++K+ E+KK+E +EK + + E++ ++ EE
Sbjct: 2279 QVEKEEE----EKKKKKKEKKKEEVQEKEEV----FEEKEEIMSEE 2316
Score = 52.8 bits (125), Expect = 2e-06
Identities = 82/353 (23%), Positives = 151/353 (42%), Gaps = 44/353 (12%)
Query: 590 SKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAK 649
SK Q Y++ + + EE +E EEKE+ + + ++ + W + + A+
Sbjct: 1531 SKSKEQQYKDEEEVTL---EEEVSREGEEKEQQVTEEQRHIQEEHKWAR----IHRKRAR 1583
Query: 650 GNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLED---AANKSSGH 706
+ Q + + +++R + + LA + + +D A
Sbjct: 1584 A------EKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKF 1637
Query: 707 MQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREE----AERERLRIAEE 762
Q + + RG + +L K+++L K + + EE+K ++ AE + + +A++
Sbjct: 1638 AQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNI-LAQK 1696
Query: 763 KEERRLAEQRARIQQ-EYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEK 821
EE EQ Q+ E +E E+ EE K EE L +E K E KKK EE+
Sbjct: 1697 VEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEE---LNQEEGKLVEEKKKLAEEE 1753
Query: 822 YNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSII---RSFIHES 878
L Q R+ L EETK + Q ++ + K+A ++ P + + R + E
Sbjct: 1754 EALAWQ----REKLSEEETK-LAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEK 1808
Query: 879 SMSRAQSPPVPARKNQLRAEEE--KKNVIM----ELSEMRKQLRSEERRLQER 925
M AQ R+ + + EE K +I+ L++ +K L E+ +L +R
Sbjct: 1809 KMKLAQK-----RERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQR 1856
Score = 49.7 bits (117), Expect = 2e-05
Identities = 51/255 (20%), Positives = 111/255 (43%), Gaps = 29/255 (11%)
Query: 722 EPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEE 781
E E + K+Q++ + Q E K R +R R +EER+LA++ ++ QE +
Sbjct: 1549 EVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQ 1608
Query: 782 EQEKKRE---------KEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCER 832
+++R+ +++ + + E EE + K +E EK + + ++
Sbjct: 1609 LAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKK 1668
Query: 833 DNLIGEETKHMRQPSPIVPALQNKIASKL----QRPPSVDSIIRSFIHESSMSRAQSPPV 888
+ E + + + + ++N +A K+ QR ++D + E +
Sbjct: 1669 WEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEEL 1728
Query: 889 PARKNQLRAE-----EEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERN 943
++ +L E EEKK +L+E + L + +L E + ++E+ I++KE+
Sbjct: 1729 SWKEEELNQEEGKLVEEKK----KLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEK- 1783
Query: 944 PMDIFDMARHRLQAP 958
+A+H+ + P
Sbjct: 1784 ------LAQHKEKMP 1792
Score = 48.1 bits (113), Expect = 5e-05
Identities = 57/245 (23%), Positives = 114/245 (46%), Gaps = 38/245 (15%)
Query: 732 QELYKNFLRFQIEEKKQREEAE----RERLRIAEEKEERRLAEQ-------------RAR 774
+++++N L + +E++ ++E E E R EEKE++ EQ R R
Sbjct: 1522 KQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKR 1581
Query: 775 IQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEA---------ERKKKEEEEKYNLQ 825
+ E + QE+++ +EE++L EE +LA+E +K A +R+ + E K+ +
Sbjct: 1582 ARAEKKRAQEERKLAQEEEKLAQEER-QLAQEERKLAQAYVKITQDDREMAQAEGKFAQK 1640
Query: 826 LQHYCERDNLIGEETKHMRQPS-------PIVPALQNKIASKLQRPPSVDSIIRSFIHES 878
+ +R + +E + + Q V + K+A K + V +I+ + E
Sbjct: 1641 EETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEEL 1700
Query: 879 SMSRAQSPPVPARKNQLRAE-EEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPI 937
R Q+ + ++ +L E EE + + ELS ++L EE +L E + ++E
Sbjct: 1701 P-QREQN--LDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALA 1757
Query: 938 RKKER 942
++E+
Sbjct: 1758 WQREK 1762
Score = 47.0 bits (110), Expect = 1e-04
Identities = 50/195 (25%), Positives = 84/195 (43%), Gaps = 55/195 (28%)
Query: 744 EEKKQREEAERERLRIAEEK---EERRLAEQRARIQQEYEEEQEKK-REKEEEQRLKNEE 799
EE ++R E E+L A EK EE L E + +E+++ E K +EQ+ K+EE
Sbjct: 1483 EEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEE 1542
Query: 800 HIRLAEERQKEAERKKKE-EEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIA 858
+ L EE +E E K+++ EE+ ++Q +H R
Sbjct: 1543 EVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWAR-------------------------- 1576
Query: 859 SKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSE 918
IH RA++ A++ + A+EE+K L++ +QL E
Sbjct: 1577 ----------------IHR---KRARAEKKRAQEERKLAQEEEK-----LAQEERQLAQE 1612
Query: 919 ERRLQERLLHMDSDD 933
ER+L + + + DD
Sbjct: 1613 ERKLAQAYVKITQDD 1627
Score = 43.5 bits (101), Expect = 0.001
Identities = 57/270 (21%), Positives = 113/270 (41%), Gaps = 44/270 (16%)
Query: 718 NVFGEPPTELQIKQQEL--YKNFLRFQIEEKK--------QREEAERERLRIAEEKEERR 767
N+ + EL ++Q L + L ++EE + + EE +E ++ EEK++
Sbjct: 1691 NILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLA 1750
Query: 768 LAEQRARIQQEYEEEQEKKREKEEEQRLKN------------EEHIRLAEERQKEAERKK 815
E+ Q+E E+E K +EEE ++ EE RL +R++ E+K
Sbjct: 1751 EEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKM 1810
Query: 816 K--EEEEKYNLQLQHYC-------ERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPS 866
K ++ E++ ++ ++ NL E+ ++ + +N + +K + S
Sbjct: 1811 KLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHS 1870
Query: 867 VDSIIR---------SFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRS 917
+++ + + Q +K + AE EKK V +E S +KQ
Sbjct: 1871 KKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQ--- 1927
Query: 918 EERRLQERLLHMDSDDEIPIRKKERNPMDI 947
E+ QE++ + +K+ R +DI
Sbjct: 1928 -EKLAQEKMKLALEKAMVQGKKRLRGELDI 1956
Score = 41.6 bits (96), Expect = 0.005
Identities = 102/535 (19%), Positives = 224/535 (41%), Gaps = 67/535 (12%)
Query: 564 VGQNELKITSDQVINSGLIFEDKPKPS--KQSLQSYQEALQQQIREREERRKKEREEKEE 621
+ + E K+ ++ L+ ++K K + K+ + +E L ++ + E++ K +++E
Sbjct: 1763 LSEEETKLAQEEE----LLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRER 1818
Query: 622 YEAKLEA----EMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYED 677
+ +E +M Y L K NL + ++ ++ + +N + T+
Sbjct: 1819 WINSMEELTKNKMILYQKKN-------LAQEKKNLAQEKEKLAQRKENLLYNKERLTHS- 1870
Query: 678 KRAVVSLDPNLATSN---AENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQEL 734
K+ +V + L N A+ E + ++ + + L KQ++L
Sbjct: 1871 KKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKL 1930
Query: 735 YKNFLRFQIEEKK-QREEAERERLRIAEEKEE-------RRLAEQRARIQQEYE-----E 781
+ ++ +E+ Q ++ R L IA KEE +RLAE++ R+ + E E
Sbjct: 1931 AQEKMKLALEKAMVQGKKRLRGELDIA--KEEKALNLEMKRLAEEKMRLVEGKETLSKGE 1988
Query: 782 EQEKKREKEE--------EQRLKNEEHIRLAEER---QKEAERKKKEEEEKYNLQLQHYC 830
E R+++ E++L EE I L E+R +E+E K + E + + +
Sbjct: 1989 TPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLE--FTRGQRIFV 2046
Query: 831 ERDNLIGEETKHM---RQPSPIVPALQNKIASKLQRPPSVD-SIIRSFIHESSMSRAQSP 886
+ + + ++ + R+ PA NKI LQ+ + + + I + M RA
Sbjct: 2047 QGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRA--- 2103
Query: 887 PVPARKNQLRAEEEKKNV-IMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPM 945
+ ++ +L E+ K ++ + SE R +L +E++L + + + I K+E+
Sbjct: 2104 -LFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTE 2162
Query: 946 DIFDMARHRLQAPVRRQSPKGLDAATFQNVHDF-----NELKDRDSETRVDLKF-MYLDP 999
+ +AR + + + G++ + V F + K+ + KF +D
Sbjct: 2163 EESKLARKHSEVILDDEEEGGIEE---EEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDE 2219
Query: 1000 PRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQRMPRDDTSD 1054
+ ++LL E +K+ + +E + + + +VRE+ R + +
Sbjct: 2220 VESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEE 2274
Score = 33.1 bits (74), Expect = 1.7
Identities = 52/222 (23%), Positives = 89/222 (40%), Gaps = 46/222 (20%)
Query: 42 DEFIEEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGS 101
+E I K R + K D P K K S+++ E ++E+ +
Sbjct: 2187 EEVIPFLKRRWRKRKEAKRGDKP----KEKFSSQVDEVE------SEEHFSEEMESLLDE 2236
Query: 102 LGIDYGLSLPLGEDYERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEK 161
L LS E+ E ++ + +EE+R++ +ER KEE +
Sbjct: 2237 LEKQESLSSEEEEEREEEEEREEEEVREE-----EEER---------------KEEEEGE 2276
Query: 162 FRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRL 221
+QVEK E K ++ K + K + + + E E + T S + EE
Sbjct: 2277 EKQVEKEEEEKKKKKK----EKKKEEVQEKEEVFEEKEEIMSEEETESLSDEE------- 2325
Query: 222 EEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAG 263
EE+ L++E++ R + I+KK + L+ QR S G
Sbjct: 2326 EEEESCSLEEEVD-REKEILKKEKQ----FKLQEQRRKSLRG 2362
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 68.6 bits (166), Expect = 4e-11
Identities = 62/263 (23%), Positives = 122/263 (46%), Gaps = 16/263 (6%)
Query: 685 DPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIE 744
+P S E L+D N H++ + R + +++ ++ R Q E
Sbjct: 151 EPPAGPSKVEQLQDETN----HLRKELESVGR-------QLQAEVENNQMLSLLNRRQEE 199
Query: 745 EKKQREEAERERLRIAEEKEERRLA-EQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRL 803
+++EE RE+ E+EER E+R R Q+E EQE++ ++EE+ ++EE +
Sbjct: 200 RLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCE 259
Query: 804 AEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQR 863
EER E E + +E+EE+ + Q + CE++ + E+ + + + + + ++ + +R
Sbjct: 260 QEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEER 319
Query: 864 PPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIME--LSEMRKQLRSEERR 921
+ + R + + R EE+++ + E L E+ + L E R
Sbjct: 320 LREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQERLR 379
Query: 922 LQ-ERLLHMDSDDEIP-IRKKER 942
Q ERL ++ E+ +R+ ER
Sbjct: 380 QQDERLWQQETLQELERLRELER 402
Score = 45.8 bits (107), Expect = 2e-04
Identities = 83/401 (20%), Positives = 148/401 (36%), Gaps = 42/401 (10%)
Query: 505 PPLATN--YRTPYDDAYYFYGSRNTFDPSLAYYGSGMMGVQPAAYVSAPVTHQLAQPVVN 562
P AT+ Y +P D A YG +L S + A S+ + QL + + +
Sbjct: 55 PDTATSGGYHSPGDSATGIYGEGRASSTTLEDLESQYQELAVALDSSSAIISQLTENINS 114
Query: 563 TV--GQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKE 620
V + E K V G + + L A ++ + ++ R+E E
Sbjct: 115 LVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELE 174
Query: 621 EYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRA 680
+L+AE+ L + + + R+ + + R E +
Sbjct: 175 SVGRQLQAEVENNQMLSL------LNRRQEERLREQEERLREQEERLREQEERLCEQEER 228
Query: 681 VVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLR 740
+ + L E L + + H + R E L+ +++ L++ R
Sbjct: 229 LREQEERLREQE-ERLCEQEERLREHEERLCEQEER---LCEQEERLREQEERLHEQEER 284
Query: 741 FQIEEKKQREEAER-----ERLRIAEEK---EERRLAEQRARIQQ--------------- 777
+E++ RE+ ER ERLR EE+ +E RL EQ R+ +
Sbjct: 285 LCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVE 344
Query: 778 ---EYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDN 834
E E QE++ E +RL E L +ER ++ + + ++E L+ ER
Sbjct: 345 KLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELERML 404
Query: 835 LIGEETKHMRQPSPI--VPALQNKIASKLQRPPSVDSIIRS 873
+G E + ++ P L N+ S LQ V + +S
Sbjct: 405 ELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKS 445
Score = 31.6 bits (70), Expect = 4.8
Identities = 44/204 (21%), Positives = 84/204 (41%), Gaps = 17/204 (8%)
Query: 132 RRYLTQERLKLERNKEYNQFLRGKEE----SSEKFRQVEKSTEPKSQR---NKKPIGQVK 184
RR + R + ER +E + LR +EE E+ R+ E+ + +R ++ + + +
Sbjct: 195 RRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHE 254
Query: 185 PDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQ-RRLEEDRYRQLDDEIELRNRRIIKK 243
L Q + CE E R+ E E L Q RL E R + E LR + ++
Sbjct: 255 ERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQE--ER 312
Query: 244 ANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQD-----PEVSEEMDER 298
E+ + +R + +P + +++ ++ + +Q+ + EE++E
Sbjct: 313 LCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEEL 372
Query: 299 FRYE--SDFDRRLSRVYTNDRMHR 320
E D RL + T + R
Sbjct: 373 LEQERLRQQDERLWQQETLQELER 396
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 68.6 bits (166), Expect = 4e-11
Identities = 71/255 (27%), Positives = 113/255 (44%), Gaps = 59/255 (23%)
Query: 728 QIKQQELYKNFLRFQIE-EKKQREEAERERLRIAEEKEE-----RRLAEQRARIQQEYEE 781
Q ++++ K R Q+E EKK+RE AE+E+ RI EKEE +++ EQ + Q+E EE
Sbjct: 308 QAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEE 367
Query: 782 E--------QEKKREKEEEQRL----------------------KNEEHI--RLAEERQK 809
+ QE+KR KEE +RL KN+E + LAE K
Sbjct: 368 QTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAK 427
Query: 810 EA---ERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQ----------PSPIVPALQNK 856
A E KKK+EEE Q + + +++L E+TK + P P++P +N+
Sbjct: 428 IALLEEAKKKKEEEATEWQHKAFAAQEDL--EKTKEELKTVMSAPPPPPPPPVIPPTENE 485
Query: 857 IASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLR 916
+ + +E M+ R + + E K + LS Q R
Sbjct: 486 HDEHDENNAEASA---ELSNEGVMNHRSE---EERVTETQKNERVKKQLQALSSELAQAR 539
Query: 917 SEERRLQERLLHMDS 931
E ++ Q +LH ++
Sbjct: 540 DETKKTQNDVLHAEN 554
Score = 37.4 bits (85), Expect = 0.088
Identities = 20/73 (27%), Positives = 46/73 (63%), Gaps = 4/73 (5%)
Query: 751 EAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNE--EHIRLAEERQ 808
E ++ + + EEK +++L +RA+++ E ++ + ++EKE +R K E E ++ EE+
Sbjct: 301 EVQQMKAQAREEKHQKQL--ERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQT 358
Query: 809 KEAERKKKEEEEK 821
+A+++ +E+ K
Sbjct: 359 IKAQKELEEQTRK 371
Score = 34.7 bits (78), Expect = 0.57
Identities = 37/154 (24%), Positives = 68/154 (44%), Gaps = 8/154 (5%)
Query: 115 DYERKKHKLKEELRQDY--RRYLTQERLKLE-RNKEYNQFLRGKEESSEKFRQVEKSTEP 171
+ ++ K + +EE Q R L E+ K E KE + R KEE E+ +Q+E+ T
Sbjct: 301 EVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQT-I 359
Query: 172 KSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDD 231
K+Q+ + + +L + + + E +E K+ EA + Q + QL
Sbjct: 360 KAQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAA 419
Query: 232 EIELRNRRII----KKANEEVGISNLKHQRFASK 261
E+ +I K +E + +H+ FA++
Sbjct: 420 ELAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQ 453
Score = 32.7 bits (73), Expect = 2.2
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Query: 766 RRLAEQRARIQQEYEEEQEKKREKE-EEQRLKNEEHIRLAEERQKEAERKKKEE 818
RR +QQ + +E+K +K+ E +L+NE+ R E++KE ++KEE
Sbjct: 293 RRRKPDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEE 346
>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
sapiens]
Length = 1268
Score = 68.2 bits (165), Expect = 5e-11
Identities = 44/149 (29%), Positives = 78/149 (52%), Gaps = 23/149 (15%)
Query: 718 NVFGEPPTELQIK-QQELYKNFLRFQIEEKKQREEAERERL------------------- 757
N GEP + L + + L ++FLR Q+ K++ E R++L
Sbjct: 333 NDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQ 392
Query: 758 -RIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK 816
RI E+KE+RR E++ R ++E ++QE+++ + E++++ EE R AE Q+ ++ +
Sbjct: 393 KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLE 452
Query: 817 EEEEKYNLQLQHYCERDNLIGEETKHMRQ 845
E+ + LQ Q ERD L+ +H RQ
Sbjct: 453 EQRQAERLQRQLKQERDYLV--SLQHQRQ 479
Score = 52.4 bits (124), Expect = 3e-06
Identities = 74/350 (21%), Positives = 138/350 (39%), Gaps = 58/350 (16%)
Query: 577 INSGLIFEDKPKPSKQSLQSY--------QEALQQQIREREERRKKEREEKEE--YEAKL 626
I S L+ +P+ + L + + ++ Q+++ +R KK+R EK+E YE
Sbjct: 266 IESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSG 325
Query: 627 EAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDP 686
E N G+ L + L D R+ N
Sbjct: 326 SEEEEEENDSGEPSSILNL-PGESTLRRDFLRLQLAN----------------------- 361
Query: 687 NLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEK 746
+ +A + Q + + + + E ++ +Q+E + Q EK
Sbjct: 362 -------KERSEALRRQQLEQQQRENEEHKRQLLAERQKRIE-EQKEQRRRLEEQQRREK 413
Query: 747 KQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQ-EKKREKEEEQRLKNEEHIRLAE 805
+ R++ ERE+ R EE+ R +RA +QEY+ +Q E++R+ E QR +E L
Sbjct: 414 ELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYLVS 473
Query: 806 ERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHM---RQPSPIVPALQN------K 856
+ + E++ E++ Y+ + +E H+ + P + A Q+ K
Sbjct: 474 LQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEIPHLVAVKSQGPALTASQSVHEQPTK 533
Query: 857 IASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPA------RKNQLRAEEE 900
S Q +V S ++S +++PP+P R + LR EE+
Sbjct: 534 GLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEED 583
Score = 42.4 bits (98), Expect = 0.003
Identities = 63/266 (23%), Positives = 107/266 (40%), Gaps = 89/266 (33%)
Query: 708 QTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERR 767
Q PF R + P E Q++ Q K+ + +++ +++E E E EE+EE
Sbjct: 282 QLMKHPFIR-----DQPNERQVRIQ--LKDHIDRTKKKRGEKDETEYEYSGSEEEEEEND 334
Query: 768 LAEQRA---------------RIQQEYEEEQEK-KREKEEEQRLKNEEHIR-LAEERQKE 810
E + R+Q +E E +R++ E+Q+ +NEEH R L ERQK
Sbjct: 335 SGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKR 394
Query: 811 AERKKK-----EEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP 865
E +K+ EE+++ +L+ ER E+ +H +
Sbjct: 395 IEEQKEQRRRLEEQQRREKELRKQQER-----EQRRHYEE-------------------- 429
Query: 866 SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQER 925
Q+R EEE++ E RKQL EE+R ER
Sbjct: 430 ----------------------------QMRREEERRRAEHEQEYKRKQL--EEQRQAER 459
Query: 926 L---LHMDSDDEIPI--RKKERNPMD 946
L L + D + + +++E+ P++
Sbjct: 460 LQRQLKQERDYLVSLQHQRQEQRPVE 485
>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
sapiens]
Length = 1276
Score = 68.2 bits (165), Expect = 5e-11
Identities = 44/149 (29%), Positives = 78/149 (52%), Gaps = 23/149 (15%)
Query: 718 NVFGEPPTELQIK-QQELYKNFLRFQIEEKKQREEAERERL------------------- 757
N GEP + L + + L ++FLR Q+ K++ E R++L
Sbjct: 333 NDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQ 392
Query: 758 -RIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK 816
RI E+KE+RR E++ R ++E ++QE+++ + E++++ EE R AE Q+ ++ +
Sbjct: 393 KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLE 452
Query: 817 EEEEKYNLQLQHYCERDNLIGEETKHMRQ 845
E+ + LQ Q ERD L+ +H RQ
Sbjct: 453 EQRQAERLQRQLKQERDYLV--SLQHQRQ 479
Score = 52.4 bits (124), Expect = 3e-06
Identities = 74/350 (21%), Positives = 138/350 (39%), Gaps = 58/350 (16%)
Query: 577 INSGLIFEDKPKPSKQSLQSY--------QEALQQQIREREERRKKEREEKEE--YEAKL 626
I S L+ +P+ + L + + ++ Q+++ +R KK+R EK+E YE
Sbjct: 266 IESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSG 325
Query: 627 EAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDP 686
E N G+ L + L D R+ N
Sbjct: 326 SEEEEEENDSGEPSSILNL-PGESTLRRDFLRLQLAN----------------------- 361
Query: 687 NLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEK 746
+ +A + Q + + + + E ++ +Q+E + Q EK
Sbjct: 362 -------KERSEALRRQQLEQQQRENEEHKRQLLAERQKRIE-EQKEQRRRLEEQQRREK 413
Query: 747 KQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQ-EKKREKEEEQRLKNEEHIRLAE 805
+ R++ ERE+ R EE+ R +RA +QEY+ +Q E++R+ E QR +E L
Sbjct: 414 ELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYLVS 473
Query: 806 ERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHM---RQPSPIVPALQN------K 856
+ + E++ E++ Y+ + +E H+ + P + A Q+ K
Sbjct: 474 LQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEIPHLVAVKSQGPALTASQSVHEQPTK 533
Query: 857 IASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPA------RKNQLRAEEE 900
S Q +V S ++S +++PP+P R + LR EE+
Sbjct: 534 GLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEED 583
Score = 42.4 bits (98), Expect = 0.003
Identities = 63/266 (23%), Positives = 107/266 (40%), Gaps = 89/266 (33%)
Query: 708 QTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERR 767
Q PF R + P E Q++ Q K+ + +++ +++E E E EE+EE
Sbjct: 282 QLMKHPFIR-----DQPNERQVRIQ--LKDHIDRTKKKRGEKDETEYEYSGSEEEEEEND 334
Query: 768 LAEQRA---------------RIQQEYEEEQEK-KREKEEEQRLKNEEHIR-LAEERQKE 810
E + R+Q +E E +R++ E+Q+ +NEEH R L ERQK
Sbjct: 335 SGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKR 394
Query: 811 AERKKK-----EEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP 865
E +K+ EE+++ +L+ ER E+ +H +
Sbjct: 395 IEEQKEQRRRLEEQQRREKELRKQQER-----EQRRHYEE-------------------- 429
Query: 866 SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQER 925
Q+R EEE++ E RKQL EE+R ER
Sbjct: 430 ----------------------------QMRREEERRRAEHEQEYKRKQL--EEQRQAER 459
Query: 926 L---LHMDSDDEIPI--RKKERNPMD 946
L L + D + + +++E+ P++
Sbjct: 460 LQRQLKQERDYLVSLQHQRQEQRPVE 485
>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
sapiens]
Length = 1352
Score = 67.8 bits (164), Expect = 6e-11
Identities = 64/292 (21%), Positives = 123/292 (42%), Gaps = 43/292 (14%)
Query: 718 NVFGEPPTELQIK-QQELYKNFLRFQIEEKKQREEAERERL------------------- 757
N GEP + L + + L ++FLR Q+ K++ E R++L
Sbjct: 333 NDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQ 392
Query: 758 -RIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK 816
RI E+KE+RR E++ R ++E ++QE+++ + E++++ EE R AE Q+ R+ +
Sbjct: 393 KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLE 452
Query: 817 EEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIH 876
EE+ + + Q L+ E + + + + A +LQR + R ++
Sbjct: 453 EEQRQLEILQQQLLHEQALLLEYKRKQLE--------EQRQAERLQRQLKQE---RDYLV 501
Query: 877 ESSMSRAQSPPVPARK----NQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSD 932
R + PV + + + EK E+ E + R + ++ + SD
Sbjct: 502 SLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSPAMPHKVANRISD 561
Query: 933 DEIPIRKKERNPMDIFDMARHRLQAPVRRQSP-------KGLDAATFQNVHD 977
+P R + + + + PV Q P +G Q+VH+
Sbjct: 562 PNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKSQGPALTASQSVHE 613
Score = 46.6 bits (109), Expect = 1e-04
Identities = 59/246 (23%), Positives = 99/246 (40%), Gaps = 85/246 (34%)
Query: 708 QTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERR 767
Q PF R + P E Q++ Q K+ + +++ +++E E E EE+EE
Sbjct: 282 QLMKHPFIR-----DQPNERQVRIQ--LKDHIDRTKKKRGEKDETEYEYSGSEEEEEEND 334
Query: 768 LAEQRA---------------RIQQEYEEEQEK-KREKEEEQRLKNEEHIR-LAEERQKE 810
E + R+Q +E E +R++ E+Q+ +NEEH R L ERQK
Sbjct: 335 SGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKR 394
Query: 811 AE-----RKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP 865
E R++ EE+++ +L+ ER E+ +H +
Sbjct: 395 IEEQKEQRRRLEEQQRREKELRKQQER-----EQRRHYEE-------------------- 429
Query: 866 SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERR---L 922
Q+R EEE++ E +R+QL E+R+ L
Sbjct: 430 ----------------------------QMRREEERRRAEHEQEYIRRQLEEEQRQLEIL 461
Query: 923 QERLLH 928
Q++LLH
Sbjct: 462 QQQLLH 467
Score = 32.3 bits (72), Expect = 2.8
Identities = 13/48 (27%), Positives = 29/48 (60%)
Query: 582 IFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAE 629
+ ++ K ++ + + +QQ RE+E R+++ERE++ YE ++ E
Sbjct: 387 LLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRRE 434
>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
sapiens]
Length = 1360
Score = 67.8 bits (164), Expect = 6e-11
Identities = 64/292 (21%), Positives = 123/292 (42%), Gaps = 43/292 (14%)
Query: 718 NVFGEPPTELQIK-QQELYKNFLRFQIEEKKQREEAERERL------------------- 757
N GEP + L + + L ++FLR Q+ K++ E R++L
Sbjct: 333 NDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQ 392
Query: 758 -RIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK 816
RI E+KE+RR E++ R ++E ++QE+++ + E++++ EE R AE Q+ R+ +
Sbjct: 393 KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLE 452
Query: 817 EEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIH 876
EE+ + + Q L+ E + + + + A +LQR + R ++
Sbjct: 453 EEQRQLEILQQQLLHEQALLLEYKRKQLE--------EQRQAERLQRQLKQE---RDYLV 501
Query: 877 ESSMSRAQSPPVPARK----NQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSD 932
R + PV + + + EK E+ E + R + ++ + SD
Sbjct: 502 SLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSPAMPHKVANRISD 561
Query: 933 DEIPIRKKERNPMDIFDMARHRLQAPVRRQSP-------KGLDAATFQNVHD 977
+P R + + + + PV Q P +G Q+VH+
Sbjct: 562 PNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKSQGPALTASQSVHE 613
Score = 46.6 bits (109), Expect = 1e-04
Identities = 59/246 (23%), Positives = 99/246 (40%), Gaps = 85/246 (34%)
Query: 708 QTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERR 767
Q PF R + P E Q++ Q K+ + +++ +++E E E EE+EE
Sbjct: 282 QLMKHPFIR-----DQPNERQVRIQ--LKDHIDRTKKKRGEKDETEYEYSGSEEEEEEND 334
Query: 768 LAEQRA---------------RIQQEYEEEQEK-KREKEEEQRLKNEEHIR-LAEERQKE 810
E + R+Q +E E +R++ E+Q+ +NEEH R L ERQK
Sbjct: 335 SGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKR 394
Query: 811 AE-----RKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP 865
E R++ EE+++ +L+ ER E+ +H +
Sbjct: 395 IEEQKEQRRRLEEQQRREKELRKQQER-----EQRRHYEE-------------------- 429
Query: 866 SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERR---L 922
Q+R EEE++ E +R+QL E+R+ L
Sbjct: 430 ----------------------------QMRREEERRRAEHEQEYIRRQLEEEQRQLEIL 461
Query: 923 QERLLH 928
Q++LLH
Sbjct: 462 QQQLLH 467
Score = 32.3 bits (72), Expect = 2.8
Identities = 13/48 (27%), Positives = 29/48 (60%)
Query: 582 IFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAE 629
+ ++ K ++ + + +QQ RE+E R+++ERE++ YE ++ E
Sbjct: 387 LLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRRE 434
>gi|62244004 modulator of estrogen induced transcription isoform b
[Homo sapiens]
Length = 1016
Score = 67.4 bits (163), Expect = 8e-11
Identities = 57/169 (33%), Positives = 91/169 (53%), Gaps = 22/169 (13%)
Query: 728 QIKQQELYKNFLRFQI----------EEKKQREEAERERLRIAEEKEER-RLAEQRARIQ 776
++K+Q L ++ +RF+ E +RE ERER+RI E+EER RL +R R++
Sbjct: 591 KMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLE 650
Query: 777 QEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLI 836
E Q+ +RE+ E +RL+ E IR+ +ER+KEAER +E EE Q Q E+
Sbjct: 651 IE---RQKLERERMERERLERER-IRIEQERRKEAERIAREREELRRQQQQLRYEQ---- 702
Query: 837 GEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQS 885
E+ +++P + + S+ + S+D+ R F H S SR Q+
Sbjct: 703 -EKRNSLKRPRDVDHRRDDPYWSE-NKKLSLDTDAR-FGHGSDYSRQQN 748
Score = 41.6 bits (96), Expect = 0.005
Identities = 38/144 (26%), Positives = 69/144 (47%), Gaps = 22/144 (15%)
Query: 745 EKKQREEAERERLRIAEEKEERRLAE-----QRARIQQEYEEEQE-KKREKEEEQRLK-- 796
+KK+ ++ R+ + E+ +E+RL E +R R E +E +RE+ E +R++
Sbjct: 574 DKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRII 633
Query: 797 --NEEHIRLAEERQK-EAERKKKE---------EEEKYNLQLQHYCERDNLIGEETKHMR 844
EE RL ER++ E ER+K E E E+ ++ + E + + E + R
Sbjct: 634 REREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRR 693
Query: 845 QPSPIVPALQNKIASKLQRPPSVD 868
Q + + + + L+RP VD
Sbjct: 694 QQQQL--RYEQEKRNSLKRPRDVD 715
Score = 37.7 bits (86), Expect = 0.067
Identities = 99/499 (19%), Positives = 178/499 (35%), Gaps = 74/499 (14%)
Query: 716 RGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARI 775
R + G+ + ++K K + E+ R +++ K + + ++ R
Sbjct: 429 RTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRS 488
Query: 776 QQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNL 835
++ E+++ K +K E + KN+ A + E+ +K +E++ + H D
Sbjct: 489 SEKSEKKESKDTKKIEGKDEKNDNG---ASGQTSESIKKSEEKKRISSKSPGHMVILDQT 545
Query: 836 IGEETKHMRQPSPIVPALQNKI--ASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKN 893
G+ + R+ KI SK + S+D + R + P K
Sbjct: 546 KGDHCRPSRR------GRYEKIHGRSKEKERASLDK-----KRDKDYRRKEILPFEKMKE 594
Query: 894 QLRAEE----EKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFD 949
Q E E+ MEL R+++ ERR +ER+ + +ER +
Sbjct: 595 QRLREHLVRFERLRRAMEL-RRRREIAERERRERERIRII----------REREERERLQ 643
Query: 950 MARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQ 1009
R RL+ ++ + ++ + E + R R+ R+ L Q
Sbjct: 644 RERERLEIERQKLERERMERERLERERIRIEQERRKEAERI---------AREREELRRQ 694
Query: 1010 QQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQRMPRDDTSDFLKNSLLESDSAFIG 1069
QQ L EQ+KR N +K D+D R D + +N L D+
Sbjct: 695 QQQLRYEQEKR-NSLKRPR----DVD------------HRRDDPYWSENKKLSLDTDARF 737
Query: 1070 AYGETYPAIEDDV----------LPPPSQLPSARERRRNKWKG-LDIDSSRPNVAPDGLS 1118
+G Y ++ P S + S+ RR+++ G + +RP + S
Sbjct: 738 GHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPS 797
Query: 1119 LKSISSVNVDELRVRNEERMRRLNEFHNKPINTD-DESSLV---DPDDIM--KHIGDDGS 1172
+ D R L E + + + DE V D DI +H + G
Sbjct: 798 FERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHPREAGP 857
Query: 1173 NSVATEPWLRPGTSETLKR 1191
N W G+ T KR
Sbjct: 858 NPSRPTSWKSEGSMSTDKR 876
>gi|63176611 modulator of estrogen induced transcription isoform a
[Homo sapiens]
Length = 1034
Score = 67.4 bits (163), Expect = 8e-11
Identities = 57/169 (33%), Positives = 91/169 (53%), Gaps = 22/169 (13%)
Query: 728 QIKQQELYKNFLRFQI----------EEKKQREEAERERLRIAEEKEER-RLAEQRARIQ 776
++K+Q L ++ +RF+ E +RE ERER+RI E+EER RL +R R++
Sbjct: 609 KMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLE 668
Query: 777 QEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLI 836
E Q+ +RE+ E +RL+ E IR+ +ER+KEAER +E EE Q Q E+
Sbjct: 669 IE---RQKLERERMERERLERER-IRIEQERRKEAERIAREREELRRQQQQLRYEQ---- 720
Query: 837 GEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQS 885
E+ +++P + + S+ + S+D+ R F H S SR Q+
Sbjct: 721 -EKRNSLKRPRDVDHRRDDPYWSE-NKKLSLDTDAR-FGHGSDYSRQQN 766
Score = 41.6 bits (96), Expect = 0.005
Identities = 38/144 (26%), Positives = 69/144 (47%), Gaps = 22/144 (15%)
Query: 745 EKKQREEAERERLRIAEEKEERRLAE-----QRARIQQEYEEEQE-KKREKEEEQRLK-- 796
+KK+ ++ R+ + E+ +E+RL E +R R E +E +RE+ E +R++
Sbjct: 592 DKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRII 651
Query: 797 --NEEHIRLAEERQK-EAERKKKE---------EEEKYNLQLQHYCERDNLIGEETKHMR 844
EE RL ER++ E ER+K E E E+ ++ + E + + E + R
Sbjct: 652 REREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRR 711
Query: 845 QPSPIVPALQNKIASKLQRPPSVD 868
Q + + + + L+RP VD
Sbjct: 712 QQQQL--RYEQEKRNSLKRPRDVD 733
Score = 37.7 bits (86), Expect = 0.067
Identities = 99/499 (19%), Positives = 178/499 (35%), Gaps = 74/499 (14%)
Query: 716 RGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARI 775
R + G+ + ++K K + E+ R +++ K + + ++ R
Sbjct: 447 RTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRS 506
Query: 776 QQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNL 835
++ E+++ K +K E + KN+ A + E+ +K +E++ + H D
Sbjct: 507 SEKSEKKESKDTKKIEGKDEKNDNG---ASGQTSESIKKSEEKKRISSKSPGHMVILDQT 563
Query: 836 IGEETKHMRQPSPIVPALQNKI--ASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKN 893
G+ + R+ KI SK + S+D + R + P K
Sbjct: 564 KGDHCRPSRR------GRYEKIHGRSKEKERASLDK-----KRDKDYRRKEILPFEKMKE 612
Query: 894 QLRAEE----EKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFD 949
Q E E+ MEL R+++ ERR +ER+ + +ER +
Sbjct: 613 QRLREHLVRFERLRRAMEL-RRRREIAERERRERERIRII----------REREERERLQ 661
Query: 950 MARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQ 1009
R RL+ ++ + ++ + E + R R+ R+ L Q
Sbjct: 662 RERERLEIERQKLERERMERERLERERIRIEQERRKEAERI---------AREREELRRQ 712
Query: 1010 QQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQRMPRDDTSDFLKNSLLESDSAFIG 1069
QQ L EQ+KR N +K D+D R D + +N L D+
Sbjct: 713 QQQLRYEQEKR-NSLKRPR----DVD------------HRRDDPYWSENKKLSLDTDARF 755
Query: 1070 AYGETYPAIEDDV----------LPPPSQLPSARERRRNKWKG-LDIDSSRPNVAPDGLS 1118
+G Y ++ P S + S+ RR+++ G + +RP + S
Sbjct: 756 GHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPS 815
Query: 1119 LKSISSVNVDELRVRNEERMRRLNEFHNKPINTD-DESSLV---DPDDIM--KHIGDDGS 1172
+ D R L E + + + DE V D DI +H + G
Sbjct: 816 FERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHPREAGP 875
Query: 1173 NSVATEPWLRPGTSETLKR 1191
N W G+ T KR
Sbjct: 876 NPSRPTSWKSEGSMSTDKR 894
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 67.0 bits (162), Expect = 1e-10
Identities = 49/145 (33%), Positives = 82/145 (56%), Gaps = 25/145 (17%)
Query: 721 GEPPTELQIK-QQELYKNFLRFQIEEKKQREEA-------ERERLRIAEEKEERRLAEQR 772
GEP + + + + L ++FLR Q +E K+R EA + ++LR EE + + LAE++
Sbjct: 338 GEPSSIVNVPGESTLRRDFLRLQ-QENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQ 396
Query: 773 ARIQQEYEE----------EQEKKREKEEEQRLKNEEHIRLAEE---RQKEAERKKKEEE 819
RI+Q+ E+ E+E +R++E EQR + +E R EE R+KE E +++ EE
Sbjct: 397 KRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEE 456
Query: 820 EKYNLQL-QHYCERDNLIGEETKHM 843
EK ++ Q Y R + EE +H+
Sbjct: 457 EKRRVEREQEYIRRQ--LEEEQRHL 479
Score = 65.9 bits (159), Expect = 2e-10
Identities = 63/199 (31%), Positives = 97/199 (48%), Gaps = 41/199 (20%)
Query: 726 ELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYE----E 781
E Q+++QE YK L + E+++R E ++E+ R EE++ R E+ AR QQE E E
Sbjct: 378 EQQLREQEEYKRQL---LAERQKRIEQQKEQRRRLEEQQRR---EREARRQQEREQRRRE 431
Query: 782 EQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK------EEEEKY--NLQLQHYCERD 833
++EK+R +E E+R K EE R AEE ++ ER+++ EEE+++ LQ Q E+
Sbjct: 432 QEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQA 491
Query: 834 NLIGEETK----HMRQPSPIVPALQNKIAS-----------KLQRPPSVDSIIRSFIHES 878
L+ + + H +QP P P + S R V+ R H S
Sbjct: 492 MLLHDHRRPHPQHSQQPPP--PQQERSKPSFHAPEPKAHYEPADRAREVEDRFRKTNHSS 549
Query: 879 ------SMSRAQSPPVPAR 891
R PPVP+R
Sbjct: 550 PEAQSKQTGRVLEPPVPSR 568
Score = 41.6 bits (96), Expect = 0.005
Identities = 50/215 (23%), Positives = 85/215 (39%), Gaps = 56/215 (26%)
Query: 744 EEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKE--EEQRLKNEEHI 801
EE+++ E E E I E L R+QQE +E E R ++ +EQ+L+ +E
Sbjct: 328 EEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEY 387
Query: 802 RLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKL 861
+ RQ AER+K+ E++K E+ + E+ + R+
Sbjct: 388 K----RQLLAERQKRIEQQK---------EQRRRLEEQQRRERE---------------- 418
Query: 862 QRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERR 921
+R Q + Q R E+E+K + EL RK+ E RR
Sbjct: 419 -------------------ARRQQ-----EREQRRREQEEKRRLEELERRRKE-EEERRR 453
Query: 922 LQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQ 956
+E ++ + E R+ E + + + LQ
Sbjct: 454 AEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQ 488
Score = 33.9 bits (76), Expect = 0.97
Identities = 54/247 (21%), Positives = 102/247 (41%), Gaps = 31/247 (12%)
Query: 723 PPTELQIKQQELYKNFLRF----QIEEKKQREEAER--ERLRIAEEKEERRLAEQRARIQ 776
PP L+ K+ K F F ++ QR E+ + I ++ ER++ R +++
Sbjct: 249 PPPRLKSKKWS--KKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQV---RIQLK 303
Query: 777 QEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNL- 835
+ ++K+ EK+E E +EE ++E ++ E N+ + RD L
Sbjct: 304 DHIDRTRKKRGEKDE-----TEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLR 358
Query: 836 IGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQL 895
+ +E K + AL+ + + Q+ + R + E + + +K Q
Sbjct: 359 LQQENKERSE------ALRRQQLLQEQQLREQEEYKRQLLAE------RQKRIEQQKEQR 406
Query: 896 RAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRL 955
R EE++ E R+Q R + RR QE ++ + ++ER + R
Sbjct: 407 RRLEEQQR--REREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVERE 464
Query: 956 QAPVRRQ 962
Q +RRQ
Sbjct: 465 QEYIRRQ 471
Score = 31.2 bits (69), Expect = 6.3
Identities = 24/89 (26%), Positives = 43/89 (48%), Gaps = 16/89 (17%)
Query: 552 VTHQLAQP--VVNTVGQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIRERE 609
V Q +P +VN G++ L+ L + + K ++L+ Q +QQ+RE+E
Sbjct: 333 VPEQEGEPSSIVNVPGESTLR-------RDFLRLQQENKERSEALRRQQLLQEQQLREQE 385
Query: 610 E-------RRKKEREEKEEYEAKLEAEMR 631
E R+K E+++E +LE + R
Sbjct: 386 EYKRQLLAERQKRIEQQKEQRRRLEEQQR 414
Score = 30.8 bits (68), Expect = 8.2
Identities = 32/137 (23%), Positives = 62/137 (45%), Gaps = 15/137 (10%)
Query: 112 LGEDYERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEP 171
L D+ R + + KE R+ L QE+ E+ + Q L +++ E+ ++ + E
Sbjct: 352 LRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEE 411
Query: 172 KSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDD 231
+ +R ++ Q + + Q E E R EEL +R+ EE+R R ++
Sbjct: 412 QQRREREARRQQERE-----QRRREQEEKRR---------LEELERRRKEEEERRRAEEE 457
Query: 232 EIEL-RNRRIIKKANEE 247
+ + R + I++ EE
Sbjct: 458 KRRVEREQEYIRRQLEE 474
Score = 30.8 bits (68), Expect = 8.2
Identities = 17/49 (34%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 582 IFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREE-KEEYEAKLEAE 629
+ ++ K +Q + + +QQ RERE RR++ERE+ + E E K E
Sbjct: 391 LLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLE 439
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 67.0 bits (162), Expect = 1e-10
Identities = 49/145 (33%), Positives = 82/145 (56%), Gaps = 25/145 (17%)
Query: 721 GEPPTELQIK-QQELYKNFLRFQIEEKKQREEA-------ERERLRIAEEKEERRLAEQR 772
GEP + + + + L ++FLR Q +E K+R EA + ++LR EE + + LAE++
Sbjct: 338 GEPSSIVNVPGESTLRRDFLRLQ-QENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQ 396
Query: 773 ARIQQEYEE----------EQEKKREKEEEQRLKNEEHIRLAEE---RQKEAERKKKEEE 819
RI+Q+ E+ E+E +R++E EQR + +E R EE R+KE E +++ EE
Sbjct: 397 KRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEE 456
Query: 820 EKYNLQL-QHYCERDNLIGEETKHM 843
EK ++ Q Y R + EE +H+
Sbjct: 457 EKRRVEREQEYIRRQ--LEEEQRHL 479
Score = 65.1 bits (157), Expect = 4e-10
Identities = 50/139 (35%), Positives = 81/139 (58%), Gaps = 22/139 (15%)
Query: 726 ELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYE----E 781
E Q+++QE YK L + E+++R E ++E+ R EE++ R E+ AR QQE E E
Sbjct: 378 EQQLREQEEYKRQL---LAERQKRIEQQKEQRRRLEEQQRR---EREARRQQEREQRRRE 431
Query: 782 EQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK------EEEEKY--NLQLQHYCERD 833
++EK+R +E E+R K EE R AEE ++ ER+++ EEE+++ LQ Q E+
Sbjct: 432 QEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQA 491
Query: 834 NLIGEETK----HMRQPSP 848
L+ + + H +QP P
Sbjct: 492 MLLHDHRRPHPQHSQQPPP 510
Score = 51.6 bits (122), Expect = 5e-06
Identities = 49/184 (26%), Positives = 82/184 (44%), Gaps = 35/184 (19%)
Query: 744 EEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKE--EEQRLKNEEHI 801
EE+++ E E E I E L R+QQE +E E R ++ +EQ+L+ +E
Sbjct: 328 EEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEY 387
Query: 802 R--LAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIAS 859
+ L ERQK E++K E++ L+ Q ER+ +E + R+ + +
Sbjct: 388 KRQLLAERQKRIEQQK---EQRRRLEEQQRREREARRQQEREQRRREQE-----EKRRLE 439
Query: 860 KLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEE 919
+L+R + + + RAEEEK+ V E +R+QL E+
Sbjct: 440 ELERRRKEE-----------------------EERRRAEEEKRRVEREQEYIRRQLEEEQ 476
Query: 920 RRLQ 923
R L+
Sbjct: 477 RHLE 480
Score = 31.2 bits (69), Expect = 6.3
Identities = 24/89 (26%), Positives = 43/89 (48%), Gaps = 16/89 (17%)
Query: 552 VTHQLAQP--VVNTVGQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIRERE 609
V Q +P +VN G++ L+ L + + K ++L+ Q +QQ+RE+E
Sbjct: 333 VPEQEGEPSSIVNVPGESTLR-------RDFLRLQQENKERSEALRRQQLLQEQQLREQE 385
Query: 610 E-------RRKKEREEKEEYEAKLEAEMR 631
E R+K E+++E +LE + R
Sbjct: 386 EYKRQLLAERQKRIEQQKEQRRRLEEQQR 414
Score = 30.8 bits (68), Expect = 8.2
Identities = 32/137 (23%), Positives = 62/137 (45%), Gaps = 15/137 (10%)
Query: 112 LGEDYERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEP 171
L D+ R + + KE R+ L QE+ E+ + Q L +++ E+ ++ + E
Sbjct: 352 LRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEE 411
Query: 172 KSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDD 231
+ +R ++ Q + + Q E E R EEL +R+ EE+R R ++
Sbjct: 412 QQRREREARRQQERE-----QRRREQEEKRR---------LEELERRRKEEEERRRAEEE 457
Query: 232 EIEL-RNRRIIKKANEE 247
+ + R + I++ EE
Sbjct: 458 KRRVEREQEYIRRQLEE 474
Score = 30.8 bits (68), Expect = 8.2
Identities = 17/49 (34%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 582 IFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREE-KEEYEAKLEAE 629
+ ++ K +Q + + +QQ RERE RR++ERE+ + E E K E
Sbjct: 391 LLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLE 439
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 67.0 bits (162), Expect = 1e-10
Identities = 49/145 (33%), Positives = 82/145 (56%), Gaps = 25/145 (17%)
Query: 721 GEPPTELQIK-QQELYKNFLRFQIEEKKQREEA-------ERERLRIAEEKEERRLAEQR 772
GEP + + + + L ++FLR Q +E K+R EA + ++LR EE + + LAE++
Sbjct: 338 GEPSSIVNVPGESTLRRDFLRLQ-QENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQ 396
Query: 773 ARIQQEYEE----------EQEKKREKEEEQRLKNEEHIRLAEE---RQKEAERKKKEEE 819
RI+Q+ E+ E+E +R++E EQR + +E R EE R+KE E +++ EE
Sbjct: 397 KRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEE 456
Query: 820 EKYNLQL-QHYCERDNLIGEETKHM 843
EK ++ Q Y R + EE +H+
Sbjct: 457 EKRRVEREQEYIRRQ--LEEEQRHL 479
Score = 62.4 bits (150), Expect = 3e-09
Identities = 57/183 (31%), Positives = 96/183 (52%), Gaps = 31/183 (16%)
Query: 726 ELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYE----E 781
E Q+++QE YK L + E+++R E ++E+ R EE++ R E+ AR QQE E E
Sbjct: 378 EQQLREQEEYKRQL---LAERQKRIEQQKEQRRRLEEQQRR---EREARRQQEREQRRRE 431
Query: 782 EQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK------EEEEKY--NLQLQHYCERD 833
++EK+R +E E+R K EE R AEE ++ ER+++ EEE+++ LQ Q E+
Sbjct: 432 QEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQA 491
Query: 834 NLIGEETKHMRQPSPIVPALQNKIASKLQRP-PSVDSIIRSFIHESSM---SRAQSPPVP 889
L+ + M +++ A +LQR + + S H+ +Q PP P
Sbjct: 492 MLLECRWREME---------EHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPP 542
Query: 890 ARK 892
++
Sbjct: 543 QQE 545
Score = 58.5 bits (140), Expect = 4e-08
Identities = 77/329 (23%), Positives = 138/329 (41%), Gaps = 53/329 (16%)
Query: 595 QSYQEALQQQIREREERRKKEREEKE--EYEAKLEAEMRTYNPWGKGGGGAPLR-DAKGN 651
Q + ++ Q+++ +R +K+R EK+ EYE E P +G + + +
Sbjct: 292 QPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGEST 351
Query: 652 LITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQS 711
L D R+ ++N + R+ +R + + L + A + Q +
Sbjct: 352 LRRDFLRLQQENKE-------RSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKE 404
Query: 712 SPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQ 771
R + + E + ++Q+ + R Q EEK++ EE ER R EE+E RR E+
Sbjct: 405 Q---RRRLEEQQRREREARRQQEREQRRREQ-EEKRRLEELERRR---KEEEERRRAEEE 457
Query: 772 RARIQQEYE------EEQEKKREKEEEQRLKNEEHI------RLAEERQKEAERKKKEEE 819
+ R+++E E EE+++ E ++Q L+ + + + E RQ E +++ ++E
Sbjct: 458 KRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQE 517
Query: 820 EKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIAS-----------KLQRPPSVD 868
+ Y L LQH R + +H +QP P P + S R V+
Sbjct: 518 QAYLLSLQHDHRRPH-----PQHSQQPPP--PQQERSKPSFHAPEPKAHYEPADRAREVE 570
Query: 869 SIIRSFIHES------SMSRAQSPPVPAR 891
R H S R PPVP+R
Sbjct: 571 DRFRKTNHSSPEAQSKQTGRVLEPPVPSR 599
Score = 51.6 bits (122), Expect = 5e-06
Identities = 49/184 (26%), Positives = 82/184 (44%), Gaps = 35/184 (19%)
Query: 744 EEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKE--EEQRLKNEEHI 801
EE+++ E E E I E L R+QQE +E E R ++ +EQ+L+ +E
Sbjct: 328 EEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEY 387
Query: 802 R--LAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIAS 859
+ L ERQK E++K E++ L+ Q ER+ +E + R+ + +
Sbjct: 388 KRQLLAERQKRIEQQK---EQRRRLEEQQRREREARRQQEREQRRREQE-----EKRRLE 439
Query: 860 KLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEE 919
+L+R + + + RAEEEK+ V E +R+QL E+
Sbjct: 440 ELERRRKEE-----------------------EERRRAEEEKRRVEREQEYIRRQLEEEQ 476
Query: 920 RRLQ 923
R L+
Sbjct: 477 RHLE 480
Score = 40.4 bits (93), Expect = 0.010
Identities = 84/424 (19%), Positives = 165/424 (38%), Gaps = 76/424 (17%)
Query: 552 VTHQLAQP--VVNTVGQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIRERE 609
V Q +P +VN G++ L+ L + + K ++L+ Q +QQ+RE+E
Sbjct: 333 VPEQEGEPSSIVNVPGESTLR-------RDFLRLQQENKERSEALRRQQLLQEQQLREQE 385
Query: 610 E-------RRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQ 662
E R+K E+++E +LE + R R+A+ + R
Sbjct: 386 EYKRQLLAERQKRIEQQKEQRRRLEEQQRRE------------REARRQQEREQRR---- 429
Query: 663 NIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGE 722
R E+KR + L+ E A + ++ + R E
Sbjct: 430 ----------REQEEKRRLEELE---RRRKEEEERRRAEEEKRRVEREQEYIRR--QLEE 474
Query: 723 PPTELQIKQQELYKN---FLRFQIEEKKQREEAERERLRIAEEK--------EERRLAEQ 771
L++ QQ+L + L + E ++ +AER + ++ +E+ + RR Q
Sbjct: 475 EQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQ 534
Query: 772 RARIQQEYEEEQEKKREKEEEQRLKNE--EHIRLAEERQKEAERKKKEEEEKYNLQLQHY 829
++ ++E+ K E + E + R E+R ++ E + K Q
Sbjct: 535 HSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVEDRFRKTNHSSPEAQSK---QTGRV 591
Query: 830 CERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVP 889
E E+ + PALQ ++Q S + +++ + S S + S P P
Sbjct: 592 LEPPVPSRSESFSNGNSESVHPALQRPAEPQVQW--SHLASLKNNVSPVSRSHSFSDPSP 649
Query: 890 A-RKNQLRAEE----EKKNVIMELSEMRKQLRSEERRLQERLLHMDSDD---EIPIRKKE 941
+ LR+++ + V+ + S+ + + ++ R DSD+ +P+R
Sbjct: 650 KFAHHHLRSQDPCPPSRSEVLSQSSDSKSEAPDPTQKAWSR---SDSDEVPPRVPVRTTS 706
Query: 942 RNPM 945
R+P+
Sbjct: 707 RSPV 710
Score = 34.3 bits (77), Expect = 0.75
Identities = 40/180 (22%), Positives = 79/180 (43%), Gaps = 17/180 (9%)
Query: 112 LGEDYERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEP 171
L D+ R + + KE R+ L QE+ E+ + Q L +++ E+ ++ + E
Sbjct: 352 LRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEE 411
Query: 172 KSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDD 231
+ +R ++ Q + + Q E E R EEL +R+ EE+R R ++
Sbjct: 412 QQRREREARRQQERE-----QRRREQEEKRR---------LEELERRRKEEEERRRAEEE 457
Query: 232 EIEL-RNRRIIKKANEEV--GISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQD 288
+ + R + I++ EE + L+ Q +A + + R+ E R +R + Q+
Sbjct: 458 KRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQE 517
Score = 33.9 bits (76), Expect = 0.97
Identities = 54/247 (21%), Positives = 102/247 (41%), Gaps = 31/247 (12%)
Query: 723 PPTELQIKQQELYKNFLRF----QIEEKKQREEAER--ERLRIAEEKEERRLAEQRARIQ 776
PP L+ K+ K F F ++ QR E+ + I ++ ER++ R +++
Sbjct: 249 PPPRLKSKKWS--KKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQV---RIQLK 303
Query: 777 QEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNL- 835
+ ++K+ EK+E E +EE ++E ++ E N+ + RD L
Sbjct: 304 DHIDRTRKKRGEKDE-----TEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLR 358
Query: 836 IGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQL 895
+ +E K + AL+ + + Q+ + R + E + + +K Q
Sbjct: 359 LQQENKERSE------ALRRQQLLQEQQLREQEEYKRQLLAE------RQKRIEQQKEQR 406
Query: 896 RAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRL 955
R EE++ E R+Q R + RR QE ++ + ++ER + R
Sbjct: 407 RRLEEQQR--REREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVERE 464
Query: 956 QAPVRRQ 962
Q +RRQ
Sbjct: 465 QEYIRRQ 471
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 66.6 bits (161), Expect = 1e-10
Identities = 65/295 (22%), Positives = 137/295 (46%), Gaps = 38/295 (12%)
Query: 584 EDKPKPSKQSLQSYQEALQQQ---IREREERRKKEREEKEEYEAKL-EAEMRTYNPWGKG 639
E+K ++ +Q +E + +Q IRE+EE+ ++ E+ E E K+ E E + + K
Sbjct: 296 EEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEK- 354
Query: 640 GGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDA 699
+R+ + + +M RQ + D + E + + + E + +
Sbjct: 355 -----IREQEEKIREQEEKMWRQE-EKIREQDEKIQEQEEEMWRQE--------EKIREQ 400
Query: 700 ANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRI 759
K M Q E +++ +++E+++ +I E ++ + + E+LR
Sbjct: 401 EEKRQEKMWRQEKKMR------EQDEKIREQEEEMWRQ--EEKIRELEEMMQDQEEKLRE 452
Query: 760 AEEK---EERRLAEQRARIQQEYEEEQEKKRE--------KEEEQRLKNEEHIRLAEERQ 808
EEK EE ++ EQ +IQ++ E+ QE++ + K+EE+ + EE + EE+
Sbjct: 453 VEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKM 512
Query: 809 KEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQR 863
E E K +E+EEK Q + E++ + ++ + M++ + L+ ++ Q+
Sbjct: 513 WEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQK 567
Score = 64.7 bits (156), Expect = 5e-10
Identities = 83/362 (22%), Positives = 147/362 (40%), Gaps = 52/362 (14%)
Query: 613 KKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITD-LNRMHRQNIDAY---- 667
KK +E+ E + PW + G + + +L+ + L+ H + Y
Sbjct: 136 KKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKL 195
Query: 668 -HNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSS------PFARGNVF 720
DA + E R ++ D L NAE E S + Q + R +
Sbjct: 196 TKERDAPSLELYRNTIT-DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLL 254
Query: 721 GEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYE 780
P +LQ++ L K + K Q + E E + +++E ++ Q +IQ++ E
Sbjct: 255 -LPQQQLQVEADRLGKELQ--SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311
Query: 781 E--EQEKKREKEEEQRLKNEEHIR--------------LAEERQKEAERKKKEEEEKYNL 824
+ EQE K ++EE+ + EE + EE+ +E E K +E+EEK
Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR 371
Query: 825 QLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQ 884
Q + E+D I E+ + M + + + K K+ R + R Q
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWR-------------QEKKMREQ 418
Query: 885 SPPVPARKNQLRAEEEKKNVIMELSEM----RKQLRSEERRLQERLLHMDSDDEIPIRKK 940
+ ++ ++ +EEK I EL EM ++LR E ++QE M +E R++
Sbjct: 419 DEKIREQEEEMWRQEEK---IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQE 475
Query: 941 ER 942
E+
Sbjct: 476 EK 477
Score = 62.0 bits (149), Expect = 3e-09
Identities = 68/344 (19%), Positives = 141/344 (40%), Gaps = 67/344 (19%)
Query: 592 QSLQSYQEALQQQIRE----------REERRKKEREEKEEYEAKL-EAEMRTYNPWGKGG 640
+ LQS LQ Q+ E +EE+ ++ E+ +E E K+ E E++
Sbjct: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELK--------- 319
Query: 641 GGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAA 700
+R+ + + +MH Q R EDK E + +
Sbjct: 320 ----IREQEEKMWRQEEKMHEQE------EKIREQEDKM----------WRQEEKIREQE 359
Query: 701 NKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIA 760
K + + + + E ++Q +++E+++ + + +E+K++E+ R+ ++
Sbjct: 360 EKIR---EQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMR 416
Query: 761 EEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEE 820
E+ E+ R E+ Q+E E E+ + +EE+ + EE ++ EE+ +E E K + +EE
Sbjct: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEE 476
Query: 821 KYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSM 880
K Q + ++ L+ +E K Q + + E M
Sbjct: 477 KIQEQEEKTWRQEKLLKQEEKIWEQEE------------------------KMWRQEEKM 512
Query: 881 SRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQE 924
+ + R EE+ + + L + ++++ +E RLQE
Sbjct: 513 WEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQE 556
Score = 52.0 bits (123), Expect = 3e-06
Identities = 64/290 (22%), Positives = 138/290 (47%), Gaps = 23/290 (7%)
Query: 582 IFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKL-EAEMRTYNPWGKGG 640
I E + K +Q + +++ +++IRE+E++ ++ E+ E E K+ E E + + K
Sbjct: 320 IREQEEKMWRQEEKMHEQ--EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK-- 375
Query: 641 GGAPLRDAKGNLITDLNRMHRQNIDAYHNPDART---YEDKRAVVSLDPNLATSNAE--N 695
+R+ + M RQ + R + ++ + D + E
Sbjct: 376 ----IREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 696 LEDAANKSSGHMQTQSSPFAR-GNVFGEPPTELQIKQQELYKNFLRFQIEEKK--QREEA 752
E+ + MQ Q E ++Q +++++ + + Q +E+K ++E+
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
Query: 753 ERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRL--AEERQKE 810
++ +I E++E+ E++ Q+E +EQE+K +++EE +++ E+ +RL EE+ +E
Sbjct: 492 LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEE-KMR-EQEVRLWQQEEKMQE 549
Query: 811 AERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASK 860
E + +E EE+ +L E G E+ R P+ + P LQ ++ S+
Sbjct: 550 QEVRLQELEERLG-KLGQKAELLGGAGRESGSQRLPT-LTPILQVELKSQ 597
Score = 40.4 bits (93), Expect = 0.010
Identities = 73/402 (18%), Positives = 154/402 (38%), Gaps = 75/402 (18%)
Query: 42 DEFIEEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGS 101
DE ++E+ A L E +ES+ +++ K + E +++L+ + + +
Sbjct: 213 DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADR------ 266
Query: 102 LGIDYGLSLPLGEDYERKKHKLKEEL-----------RQDYRRYLTQERLKLERNKEYNQ 150
LG++ + KL+ ++ +Q+ + + +E+++ + K Q
Sbjct: 267 ----------LGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQ 316
Query: 151 FLRGKEESSEKFRQVEK---------STEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGP 201
L+ +E+ + +RQ EK E K R ++ I + + + Q + E
Sbjct: 317 ELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376
Query: 202 RKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASK 261
R+ E EE+ Q E++ R+ +++ + + R KK E+ K
Sbjct: 377 REQDEKIQEQEEEMWRQ----EEKIREQEEKRQEKMWRQEKKMREQ-----------DEK 421
Query: 262 AGIPDRRFHRFNEDRVFDRRYHRPDQDP---EVSEEMDERFRYESDFDRRLSRVYTNDRM 318
+ R E+++ + DQ+ EV E+M E + + ++ R +
Sbjct: 422 IREQEEEMWR-QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480
Query: 319 HRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDR 378
K + + I + ++ E K E + E
Sbjct: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ-----------------EQE 523
Query: 379 ELIQRRKEKYR---LELLEQMAEQQRNKRREKDLELRVAASG 417
E +QR++EK R + L +Q + Q + R ++LE R+ G
Sbjct: 524 EKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLG 565
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 66.6 bits (161), Expect = 1e-10
Identities = 65/295 (22%), Positives = 137/295 (46%), Gaps = 38/295 (12%)
Query: 584 EDKPKPSKQSLQSYQEALQQQ---IREREERRKKEREEKEEYEAKL-EAEMRTYNPWGKG 639
E+K ++ +Q +E + +Q IRE+EE+ ++ E+ E E K+ E E + + K
Sbjct: 296 EEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEK- 354
Query: 640 GGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDA 699
+R+ + + +M RQ + D + E + + + E + +
Sbjct: 355 -----IREQEEKIREQEEKMWRQE-EKIREQDEKIQEQEEEMWRQE--------EKIREQ 400
Query: 700 ANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRI 759
K M Q E +++ +++E+++ +I E ++ + + E+LR
Sbjct: 401 EEKRQEKMWRQEKKMR------EQDEKIREQEEEMWRQ--EEKIRELEEMMQDQEEKLRE 452
Query: 760 AEEK---EERRLAEQRARIQQEYEEEQEKKRE--------KEEEQRLKNEEHIRLAEERQ 808
EEK EE ++ EQ +IQ++ E+ QE++ + K+EE+ + EE + EE+
Sbjct: 453 VEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKM 512
Query: 809 KEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQR 863
E E K +E+EEK Q + E++ + ++ + M++ + L+ ++ Q+
Sbjct: 513 WEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQK 567
Score = 64.7 bits (156), Expect = 5e-10
Identities = 83/362 (22%), Positives = 147/362 (40%), Gaps = 52/362 (14%)
Query: 613 KKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITD-LNRMHRQNIDAY---- 667
KK +E+ E + PW + G + + +L+ + L+ H + Y
Sbjct: 136 KKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKL 195
Query: 668 -HNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSS------PFARGNVF 720
DA + E R ++ D L NAE E S + Q + R +
Sbjct: 196 TKERDALSLELYRNTIT-DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLL 254
Query: 721 GEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYE 780
P +LQ++ L K + K Q + E E + +++E ++ Q +IQ++ E
Sbjct: 255 -LPQQQLQVEADRLGKELQ--SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311
Query: 781 E--EQEKKREKEEEQRLKNEEHIR--------------LAEERQKEAERKKKEEEEKYNL 824
+ EQE K ++EE+ + EE + EE+ +E E K +E+EEK
Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR 371
Query: 825 QLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQ 884
Q + E+D I E+ + M + + + K K+ R + R Q
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWR-------------QEKKMREQ 418
Query: 885 SPPVPARKNQLRAEEEKKNVIMELSEM----RKQLRSEERRLQERLLHMDSDDEIPIRKK 940
+ ++ ++ +EEK I EL EM ++LR E ++QE M +E R++
Sbjct: 419 DEKIREQEEEMWRQEEK---IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQE 475
Query: 941 ER 942
E+
Sbjct: 476 EK 477
Score = 62.0 bits (149), Expect = 3e-09
Identities = 68/344 (19%), Positives = 141/344 (40%), Gaps = 67/344 (19%)
Query: 592 QSLQSYQEALQQQIRE----------REERRKKEREEKEEYEAKL-EAEMRTYNPWGKGG 640
+ LQS LQ Q+ E +EE+ ++ E+ +E E K+ E E++
Sbjct: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELK--------- 319
Query: 641 GGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAA 700
+R+ + + +MH Q R EDK E + +
Sbjct: 320 ----IREQEEKMWRQEEKMHEQE------EKIREQEDKM----------WRQEEKIREQE 359
Query: 701 NKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIA 760
K + + + + E ++Q +++E+++ + + +E+K++E+ R+ ++
Sbjct: 360 EKIR---EQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMR 416
Query: 761 EEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEE 820
E+ E+ R E+ Q+E E E+ + +EE+ + EE ++ EE+ +E E K + +EE
Sbjct: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEE 476
Query: 821 KYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSM 880
K Q + ++ L+ +E K Q + + E M
Sbjct: 477 KIQEQEEKTWRQEKLLKQEEKIWEQEE------------------------KMWRQEEKM 512
Query: 881 SRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQE 924
+ + R EE+ + + L + ++++ +E RLQE
Sbjct: 513 WEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQE 556
Score = 52.0 bits (123), Expect = 3e-06
Identities = 64/290 (22%), Positives = 138/290 (47%), Gaps = 23/290 (7%)
Query: 582 IFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKL-EAEMRTYNPWGKGG 640
I E + K +Q + +++ +++IRE+E++ ++ E+ E E K+ E E + + K
Sbjct: 320 IREQEEKMWRQEEKMHEQ--EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK-- 375
Query: 641 GGAPLRDAKGNLITDLNRMHRQNIDAYHNPDART---YEDKRAVVSLDPNLATSNAE--N 695
+R+ + M RQ + R + ++ + D + E
Sbjct: 376 ----IREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 696 LEDAANKSSGHMQTQSSPFAR-GNVFGEPPTELQIKQQELYKNFLRFQIEEKK--QREEA 752
E+ + MQ Q E ++Q +++++ + + Q +E+K ++E+
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
Query: 753 ERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRL--AEERQKE 810
++ +I E++E+ E++ Q+E +EQE+K +++EE +++ E+ +RL EE+ +E
Sbjct: 492 LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEE-KMR-EQEVRLWQQEEKMQE 549
Query: 811 AERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASK 860
E + +E EE+ +L E G E+ R P+ + P LQ ++ S+
Sbjct: 550 QEVRLQELEERLG-KLGQKAELLGGAGRESGSQRLPT-LTPILQVELKSQ 597
Score = 40.4 bits (93), Expect = 0.010
Identities = 73/402 (18%), Positives = 154/402 (38%), Gaps = 75/402 (18%)
Query: 42 DEFIEEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGS 101
DE ++E+ A L E +ES+ +++ K + E +++L+ + + +
Sbjct: 213 DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADR------ 266
Query: 102 LGIDYGLSLPLGEDYERKKHKLKEEL-----------RQDYRRYLTQERLKLERNKEYNQ 150
LG++ + KL+ ++ +Q+ + + +E+++ + K Q
Sbjct: 267 ----------LGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQ 316
Query: 151 FLRGKEESSEKFRQVEK---------STEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGP 201
L+ +E+ + +RQ EK E K R ++ I + + + Q + E
Sbjct: 317 ELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376
Query: 202 RKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASK 261
R+ E EE+ Q E++ R+ +++ + + R KK E+ K
Sbjct: 377 REQDEKIQEQEEEMWRQ----EEKIREQEEKRQEKMWRQEKKMREQ-----------DEK 421
Query: 262 AGIPDRRFHRFNEDRVFDRRYHRPDQDP---EVSEEMDERFRYESDFDRRLSRVYTNDRM 318
+ R E+++ + DQ+ EV E+M E + + ++ R +
Sbjct: 422 IREQEEEMWR-QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480
Query: 319 HRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDR 378
K + + I + ++ E K E + E
Sbjct: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ-----------------EQE 523
Query: 379 ELIQRRKEKYR---LELLEQMAEQQRNKRREKDLELRVAASG 417
E +QR++EK R + L +Q + Q + R ++LE R+ G
Sbjct: 524 EKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLG 565
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform
1 [Homo sapiens]
Length = 1722
Score = 66.2 bits (160), Expect = 2e-10
Identities = 66/231 (28%), Positives = 114/231 (49%), Gaps = 31/231 (13%)
Query: 737 NFLRFQIEEK-KQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEK--------KR 787
NF ++EEK +Q EA +E+ + E+KE++ L QR R +++++EE+EK K
Sbjct: 157 NFGYCEVEEKCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQFQEEEEKRHCWMKQFKV 216
Query: 788 EKEEEQRLKNEEHIRLAEERQKE----AERKKKEEEEKYNLQLQHYCERDNLIGEETKHM 843
EK++ + ++ +E ++ +E KE E+ K+ EE NL LQ ER ++ K
Sbjct: 217 EKKKLENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEEERTRFKDQQEKEK 276
Query: 844 RQPSPIVPALQNKIASKLQRP-------PSVDSIIRSFIHESSMSRAQSPPVPARKNQLR 896
+ QN A K+Q II+ I ES +AQ K + +
Sbjct: 277 NS----LLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQI-ESKKRKAQEWKEKEAKIRQK 331
Query: 897 AEEEKKNVIME--LSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPM 945
EE +K + E + E RK+ + EER+ +E+ + +++ I K+ER +
Sbjct: 332 EEENRKRLEEEQRIKEERKKQKEEERKRREK----EYEEKKNIVKQEREQL 378
Score = 62.4 bits (150), Expect = 3e-09
Identities = 46/146 (31%), Positives = 75/146 (51%), Gaps = 31/146 (21%)
Query: 728 QIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLA------------------ 769
+ KQ E Y L Q+EE++ R + ++E+ + + K++ A
Sbjct: 246 KFKQHEEYIRNLHLQMEEERTRFKDQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGP 305
Query: 770 ------EQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAE----RKKKEEE 819
E + R QE++E++ K R+KEEE R + EE R+ EER+K+ E R++KE E
Sbjct: 306 IIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYE 365
Query: 820 EKYNLQLQHYCERDNLIGEETKHMRQ 845
EK N+ Q ER+ LI +E +R+
Sbjct: 366 EKKNIVKQ---EREQLISKEKIILRE 388
Score = 48.1 bits (113), Expect = 5e-05
Identities = 103/538 (19%), Positives = 214/538 (39%), Gaps = 91/538 (16%)
Query: 558 QPVVNTVGQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIREREERRKKERE 617
+P + + +E + D IN G + + + +QS +++QE Q+++ ++E++ K +
Sbjct: 137 EPSPHDLPMDEHVLPDDADINFG--YCEVEEKCRQSFEAWQEK-QKELEDKEKQTLKAQR 193
Query: 618 EKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYED 677
++EE + + E E R + W K + + ++ + + ++ + + +++
Sbjct: 194 DREEKQFQEEEEKR--HCWMKQF------KVEKKKLENIQKQEQDKMNDELYKEEKIWKE 245
Query: 678 K-RAVVSLDPNLATSNAEN---LEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQE 733
K + NL E +D K + Q + A +K Q
Sbjct: 246 KFKQHEEYIRNLHLQMEEERTRFKDQQEKEKNSLLKQQNNAA-------------VKIQA 292
Query: 734 LYKNFLRFQ---------IEEKKQREEAERERLRIAEEKEE--RRLAEQRARIQQEY--- 779
YK F+ +Q IE KK++ + +E+ +KEE R+ E+ RI++E
Sbjct: 293 KYKAFVAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQ 352
Query: 780 EEEQEKKREKE----------EEQRLKNEEHIRLAEERQKE---AERKKKEEEEKYNLQL 826
+EE+ K+REKE E ++L ++E I L E+ ++ + KK +L L
Sbjct: 353 KEEERKRREKEYEEKKNIVKQEREQLISKEKIILREDASQQLIISSALKKSGYNNKHLSL 412
Query: 827 QHYCE-----RDNLIGEETK-------------HMRQPSPIVPALQNKIASKLQRPPSVD 868
+ NL+ E +K +M++ L+ I KL+ S
Sbjct: 413 EDISNDKGDIAKNLVDENSKKQEDVLLWLVEESNMKENVDRQTILKESIQVKLKESISSQ 472
Query: 869 SIIRSFIHESSMSRAQSPPVPAR--KNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERL 926
+I+ F E K + + E + S+++ L+ E+ LQE
Sbjct: 473 TILADFKMEEKNENLAKKRCSEELVKQERKYENTDNKTELGNSDLKGNLK-EQFPLQE-- 529
Query: 927 LHMDSDDEIPIRKKERNP-------------MDIFDMARHRLQAPVRRQSPKGLDAATFQ 973
L D+ E I K N +I ++ + Q ++ K + +
Sbjct: 530 LKSDAQKEEKIMKHVINENTGQKTQIILGHNQEISEVKTNEEQKIIKDNQQKKIQKVEKE 589
Query: 974 NVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAK 1031
+ + N L +D +T V ++ ++++ +L+E++ +++E K
Sbjct: 590 EIQEQNGLLYKDKDTLVISVKQRSLSLTSENSKDVRENVILQEKEIYSKSKEIEENPK 647
>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform
2 [Homo sapiens]
Length = 1336
Score = 66.2 bits (160), Expect = 2e-10
Identities = 66/231 (28%), Positives = 114/231 (49%), Gaps = 31/231 (13%)
Query: 737 NFLRFQIEEK-KQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEK--------KR 787
NF ++EEK +Q EA +E+ + E+KE++ L QR R +++++EE+EK K
Sbjct: 157 NFGYCEVEEKCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQFQEEEEKRHCWMKQFKV 216
Query: 788 EKEEEQRLKNEEHIRLAEERQKE----AERKKKEEEEKYNLQLQHYCERDNLIGEETKHM 843
EK++ + ++ +E ++ +E KE E+ K+ EE NL LQ ER ++ K
Sbjct: 217 EKKKLENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEEERTRFKDQQEKEK 276
Query: 844 RQPSPIVPALQNKIASKLQRP-------PSVDSIIRSFIHESSMSRAQSPPVPARKNQLR 896
+ QN A K+Q II+ I ES +AQ K + +
Sbjct: 277 NS----LLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQI-ESKKRKAQEWKEKEAKIRQK 331
Query: 897 AEEEKKNVIME--LSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPM 945
EE +K + E + E RK+ + EER+ +E+ + +++ I K+ER +
Sbjct: 332 EEENRKRLEEEQRIKEERKKQKEEERKRREK----EYEEKKNIVKQEREQL 378
Score = 62.4 bits (150), Expect = 3e-09
Identities = 46/146 (31%), Positives = 75/146 (51%), Gaps = 31/146 (21%)
Query: 728 QIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLA------------------ 769
+ KQ E Y L Q+EE++ R + ++E+ + + K++ A
Sbjct: 246 KFKQHEEYIRNLHLQMEEERTRFKDQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGP 305
Query: 770 ------EQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAE----RKKKEEE 819
E + R QE++E++ K R+KEEE R + EE R+ EER+K+ E R++KE E
Sbjct: 306 IIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYE 365
Query: 820 EKYNLQLQHYCERDNLIGEETKHMRQ 845
EK N+ Q ER+ LI +E +R+
Sbjct: 366 EKKNIVKQ---EREQLISKEKIILRE 388
Score = 48.1 bits (113), Expect = 5e-05
Identities = 103/538 (19%), Positives = 214/538 (39%), Gaps = 91/538 (16%)
Query: 558 QPVVNTVGQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIREREERRKKERE 617
+P + + +E + D IN G + + + +QS +++QE Q+++ ++E++ K +
Sbjct: 137 EPSPHDLPMDEHVLPDDADINFG--YCEVEEKCRQSFEAWQEK-QKELEDKEKQTLKAQR 193
Query: 618 EKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYED 677
++EE + + E E R + W K + + ++ + + ++ + + +++
Sbjct: 194 DREEKQFQEEEEKR--HCWMKQF------KVEKKKLENIQKQEQDKMNDELYKEEKIWKE 245
Query: 678 K-RAVVSLDPNLATSNAEN---LEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQE 733
K + NL E +D K + Q + A +K Q
Sbjct: 246 KFKQHEEYIRNLHLQMEEERTRFKDQQEKEKNSLLKQQNNAA-------------VKIQA 292
Query: 734 LYKNFLRFQ---------IEEKKQREEAERERLRIAEEKEE--RRLAEQRARIQQEY--- 779
YK F+ +Q IE KK++ + +E+ +KEE R+ E+ RI++E
Sbjct: 293 KYKAFVAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQ 352
Query: 780 EEEQEKKREKE----------EEQRLKNEEHIRLAEERQKE---AERKKKEEEEKYNLQL 826
+EE+ K+REKE E ++L ++E I L E+ ++ + KK +L L
Sbjct: 353 KEEERKRREKEYEEKKNIVKQEREQLISKEKIILREDASQQLIISSALKKSGYNNKHLSL 412
Query: 827 QHYCE-----RDNLIGEETK-------------HMRQPSPIVPALQNKIASKLQRPPSVD 868
+ NL+ E +K +M++ L+ I KL+ S
Sbjct: 413 EDISNDKGDIAKNLVDENSKKQEDVLLWLVEESNMKENVDRQTILKESIQVKLKESISSQ 472
Query: 869 SIIRSFIHESSMSRAQSPPVPAR--KNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERL 926
+I+ F E K + + E + S+++ L+ E+ LQE
Sbjct: 473 TILADFKMEEKNENLAKKRCSEELVKQERKYENTDNKTELGNSDLKGNLK-EQFPLQE-- 529
Query: 927 LHMDSDDEIPIRKKERNP-------------MDIFDMARHRLQAPVRRQSPKGLDAATFQ 973
L D+ E I K N +I ++ + Q ++ K + +
Sbjct: 530 LKSDAQKEEKIMKHVINENTGQKTQIILGHNQEISEVKTNEEQKIIKDNQQKKIQKVEKE 589
Query: 974 NVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAK 1031
+ + N L +D +T V ++ ++++ +L+E++ +++E K
Sbjct: 590 EIQEQNGLLYKDKDTLVISVKQRSLSLTSENSKDVRENVILQEKEIYSKSKEIEENPK 647
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 65.5 bits (158), Expect = 3e-10
Identities = 54/230 (23%), Positives = 110/230 (47%), Gaps = 24/230 (10%)
Query: 731 QQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAE---QRARIQQEYEEEQEKKR 787
Q+E + R + E++K+ E ER+R R +EK++R+ E +R R ++E E++++++R
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 788 EKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPS 847
EKE +R K E+ R ++R + +KKKE +E+ ER+N E K +
Sbjct: 91 EKERRKR-KKEKKKRERKQRGRRERKKKKERKER---------ERENKQRRERKRKK--- 137
Query: 848 PIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIME 907
+ K + +R + R + + + + + E E+K
Sbjct: 138 ------RRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRER 191
Query: 908 LSEMRKQLRSEERRLQERLLHMDSDDEI--PIRKKERNPMDIFDMARHRL 955
E +K+ R ++ R ++R +D ++ P+R+ N + + + R+R+
Sbjct: 192 KKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVTVTGVFRYRI 241
Score = 49.3 bits (116), Expect = 2e-05
Identities = 30/95 (31%), Positives = 59/95 (62%), Gaps = 3/95 (3%)
Query: 730 KQQELYKNFLRFQIEEKKQREE-AERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKRE 788
K++E K R + E +KQR+E E+ER + +EK++R ++ R +++ +E +E++RE
Sbjct: 67 KKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERE 126
Query: 789 KEE--EQRLKNEEHIRLAEERQKEAERKKKEEEEK 821
++ E++ K + +ER++E ER K+E + K
Sbjct: 127 NKQRRERKRKKRRKKKRRKERKREKERGKRERKRK 161
Score = 49.3 bits (116), Expect = 2e-05
Identities = 27/107 (25%), Positives = 66/107 (61%), Gaps = 1/107 (0%)
Query: 726 ELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEK 785
E + K++E K + +E+++R++ +++R R + ER+ ++R ++E ++ +E+
Sbjct: 74 ERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRER 133
Query: 786 KREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCER 832
KR+K +++ + +E R E ++E +RKK+++EE+ + ++ ER
Sbjct: 134 KRKKRRKKK-RRKERKREKERGKRERKRKKRKKEEREKKRERNRKER 179
Score = 47.8 bits (112), Expect = 7e-05
Identities = 28/94 (29%), Positives = 56/94 (59%), Gaps = 3/94 (3%)
Query: 730 KQQELYKNFLRFQIEEKKQREEAERERL--RIAEEKEERRLAEQRARIQQEYEEEQEKKR 787
+++E K + E+KQR ER++ R E+E ++ E++ + +++ + +E+KR
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149
Query: 788 EKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEK 821
EKE +R + + R EER+K+ ER +KE +++
Sbjct: 150 EKERGKRERKRKK-RKKEEREKKRERNRKERKKE 182
Score = 44.7 bits (104), Expect = 6e-04
Identities = 47/215 (21%), Positives = 95/215 (44%), Gaps = 32/215 (14%)
Query: 607 EREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDA 666
+RE RKKER E+E+ + + E E + GK + +G R+ +
Sbjct: 31 QRESERKKERREREKRKREREKERKRER--GKKEKKKRKKRERGK------ERERKRKER 82
Query: 667 YHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTE 726
R +++R + + K G + + R E
Sbjct: 83 EKQRKERREKERR-----------KRKKEKKKRERKQRGRRERKKKK-ERKERERENKQR 130
Query: 727 LQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKK 786
+ K+++ K R + + +K+R + ER+R + +KEER +R R +++ E E++++
Sbjct: 131 RERKRKKRRKKKRRKERKREKERGKRERKRKK--RKKEEREKKRERNRKERKKERERKER 188
Query: 787 REKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEK 821
RE+++E++ +ER+K+ ERKK + ++
Sbjct: 189 RERKKERK----------KERRKKKERKKDRKTDR 213
Score = 37.0 bits (84), Expect = 0.11
Identities = 37/199 (18%), Positives = 81/199 (40%), Gaps = 5/199 (2%)
Query: 780 EEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGE- 838
+ E E+K+E+ E ++ K E ER K+ E+KK+++ E+ + + ER+ E
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKK-EKKKRKKRERGKERERKRKEREKQRKER 89
Query: 839 ETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAE 898
K R+ + K + +R + R + R + RK + R E
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKE---RKERERENKQRRERKRKKRRKKKRRKE 146
Query: 899 EEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQAP 958
+++ + RK+ + EER + + E +++ + R + +
Sbjct: 147 RKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206
Query: 959 VRRQSPKGLDAATFQNVHD 977
R++ + D+ F+ + +
Sbjct: 207 KDRKTDRQTDSQVFRPLRE 225
Score = 36.6 bits (83), Expect = 0.15
Identities = 50/234 (21%), Positives = 96/234 (41%), Gaps = 30/234 (12%)
Query: 590 SKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAK 649
SK Q E +++ RERE+R+++ +E++ K E + R GK R+ K
Sbjct: 26 SKPCTQRESERKKER-REREKRKREREKERKRERGKKEKKKRKKRERGKE------RERK 78
Query: 650 GNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQT 709
+ R+ + + E K+ E + K
Sbjct: 79 RKEREKQRKERREKERRKRKKEKKKRERKQR----------GRRERKKKKERKERERENK 128
Query: 710 QSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLA 769
Q R + + + +++E K + + +K++RE+ +RER R E K+ER
Sbjct: 129 QRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREK-KRERNR-KERKKER--- 183
Query: 770 EQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYN 823
E +E +E+K+E+++E+R K E +RQ +++ + E +N
Sbjct: 184 --------ERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFN 229
Score = 35.0 bits (79), Expect = 0.44
Identities = 40/174 (22%), Positives = 74/174 (42%), Gaps = 9/174 (5%)
Query: 117 ERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRN 176
ERK+ + K+E ++ +R +ER + + KE + + + E + R+ EK + QR
Sbjct: 53 ERKRERGKKEKKKRKKRERGKERER--KRKEREKQRKERREKERRKRKKEKKKRERKQRG 110
Query: 177 KKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIEL- 235
++ + K + + + + + E RK E + R + +R R+ + E
Sbjct: 111 RRE-RKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE 169
Query: 236 ----RNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRP 285
RNR+ KK E K +R + +R+ R DR D + RP
Sbjct: 170 KKRERNRKERKKERERKERRERKKERKKERRKKKERKKDR-KTDRQTDSQVFRP 222
Score = 33.1 bits (74), Expect = 1.7
Identities = 45/202 (22%), Positives = 85/202 (42%), Gaps = 28/202 (13%)
Query: 117 ERKKHKLKEELRQDYRRYLTQERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRN 176
ERKK + + E R+ R ++ K ER K+ + + +E E+ R+ ++ + + +R
Sbjct: 35 ERKKERREREKRKRER----EKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 177 KKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYE-ELLNQRRLEEDRYRQLDDEIEL 235
+K + K + + E + R++ E E E N++R E R ++
Sbjct: 91 EKERRKRKKEKKKR-----ERKQRGRRERKKKKERKERERENKQRRERKRKKR-----RK 140
Query: 236 RNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEM 295
+ RR +K +E G K +R +R R E+R R +R ++ E +
Sbjct: 141 KKRRKERKREKERG----KRER---------KRKKRKKEEREKKRERNRKERKKERERKE 187
Query: 296 DERFRYESDFDRRLSRVYTNDR 317
+ E +RR + DR
Sbjct: 188 RRERKKERKKERRKKKERKKDR 209
Score = 30.8 bits (68), Expect = 8.2
Identities = 19/71 (26%), Positives = 39/71 (54%), Gaps = 5/71 (7%)
Query: 584 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGA 643
E + K + + +E +++ RER++ RKKER +K+E + + + +T + +
Sbjct: 167 EREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFR----- 221
Query: 644 PLRDAKGNLIT 654
PLR++ N +T
Sbjct: 222 PLRESAFNRVT 232
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,755,705
Number of Sequences: 37866
Number of extensions: 2724358
Number of successful extensions: 58993
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 798
Number of HSP's successfully gapped in prelim test: 1190
Number of HSP's that attempted gapping in prelim test: 17462
Number of HSP's gapped (non-prelim): 17882
length of query: 1221
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1107
effective length of database: 13,930,794
effective search space: 15421388958
effective search space used: 15421388958
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.