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Search of human proteins with 23503293
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23503293 solute carrier family 16, member 11 [Homo sapiens]
(471 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23503293 solute carrier family 16, member 11 [Homo sapiens] 944 0.0
gi|42475555 monocarboxylate transporter 13 [Homo sapiens] 363 e-100
gi|114796626 solute carrier family 16, member 8 [Homo sapiens] 256 2e-68
gi|109288010 solute carrier family 16, member 3 [Homo sapiens] 249 3e-66
gi|109288012 solute carrier family 16, member 3 [Homo sapiens] 249 3e-66
gi|4759112 solute carrier family 16, member 3 [Homo sapiens] 249 3e-66
gi|24431958 solute carrier family 16, member 7 [Homo sapiens] 234 2e-61
gi|157041233 solute carrier family 16 (monocarboxylic acid trans... 228 7e-60
gi|4759116 solute carrier family 16, member 5 [Homo sapiens] 200 2e-51
gi|115583685 solute carrier family 16, member 1 [Homo sapiens] 190 2e-48
gi|18699730 solute carrier family 16, member 10 [Homo sapiens] 177 1e-44
gi|169217968 PREDICTED: similar to solute carrier family 16, mem... 158 9e-39
gi|40789261 solute carrier family 16, member 6 [Homo sapiens] 156 4e-38
gi|5730045 solute carrier family 16, member 2 [Homo sapiens] 154 2e-37
gi|41327156 solute carrier family 16 (monocarboxylic acid transp... 144 1e-34
gi|34916028 solute carrier family 16 (monocarboxylic acid transp... 131 2e-30
gi|4759114 solute carrier family 16, member 4 [Homo sapiens] 114 2e-25
gi|16445357 hypothetical protein LOC116843 [Homo sapiens] 57 4e-08
gi|4503847 solute carrier family 37 (glucose-6-phosphate transpo... 45 1e-04
gi|154350196 vesicular nucleotide transporter SLC17A9 [Homo sapi... 42 0.002
gi|126352608 elastin isoform e precursor [Homo sapiens] 37 0.039
gi|126352446 elastin isoform d precursor [Homo sapiens] 37 0.039
gi|126352322 elastin isoform c precursor [Homo sapiens] 37 0.039
gi|126352700 elastin isoform b precursor [Homo sapiens] 37 0.039
gi|126352440 elastin isoform a precursor [Homo sapiens] 37 0.039
gi|169202389 PREDICTED: similar to mCG50504 [Homo sapiens] 36 0.066
gi|39753965 hippocampus abundant transcript 1 [Homo sapiens] 36 0.066
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 35 0.19
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] 35 0.19
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] 35 0.19
>gi|23503293 solute carrier family 16, member 11 [Homo sapiens]
Length = 471
Score = 944 bits (2441), Expect = 0.0
Identities = 471/471 (100%), Positives = 471/471 (100%)
Query: 1 MPAPQRKHRRGGFSHRCFPTPQTAMTPQPAGPPDGGWGWVVAAAAFAINGLSYGLLRSLG 60
MPAPQRKHRRGGFSHRCFPTPQTAMTPQPAGPPDGGWGWVVAAAAFAINGLSYGLLRSLG
Sbjct: 1 MPAPQRKHRRGGFSHRCFPTPQTAMTPQPAGPPDGGWGWVVAAAAFAINGLSYGLLRSLG 60
Query: 61 LAFPDLAEHFDRSAQDTAWISALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFV 120
LAFPDLAEHFDRSAQDTAWISALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFV
Sbjct: 61 LAFPDLAEHFDRSAQDTAWISALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFV 120
Query: 121 FSAFASDLLHLYLGLGLLAGFGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLL 180
FSAFASDLLHLYLGLGLLAGFGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLL
Sbjct: 121 FSAFASDLLHLYLGLGLLAGFGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLL 180
Query: 181 APALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPLVLPGDPPAPPRSPLAALGLSLFT 240
APALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPLVLPGDPPAPPRSPLAALGLSLFT
Sbjct: 181 APALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPLVLPGDPPAPPRSPLAALGLSLFT 240
Query: 241 RRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWL 300
RRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWL
Sbjct: 241 RRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWL 300
Query: 301 ADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLV 360
ADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLV
Sbjct: 301 ADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLV 360
Query: 361 FGVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGS 420
FGVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGS
Sbjct: 361 FGVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGS 420
Query: 421 FIYIGLPRALPSCGPASPPATPPPETGELLPAPQAVLLSPGGPGSTLDTTC 471
FIYIGLPRALPSCGPASPPATPPPETGELLPAPQAVLLSPGGPGSTLDTTC
Sbjct: 421 FIYIGLPRALPSCGPASPPATPPPETGELLPAPQAVLLSPGGPGSTLDTTC 471
>gi|42475555 monocarboxylate transporter 13 [Homo sapiens]
Length = 426
Score = 363 bits (933), Expect = e-100
Identities = 196/397 (49%), Positives = 257/397 (64%), Gaps = 12/397 (3%)
Query: 32 PPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQAA 91
PPDGGWGWVV +AF + L +G+LRS G+ F + F+ A +WI+++ +AVQQ
Sbjct: 7 PPDGGWGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFG 66
Query: 92 SPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPAL 151
SPVGSALST++G RPVVM GG+LA+LG + ++FA+ L HLYL +GLL+G GWAL FAP L
Sbjct: 67 SPVGSALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFAPTL 126
Query: 152 GTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCG 211
LS YFSRRR LA GLALTG G SS AP Q LL + WRG+LLL+ A++LHL CG
Sbjct: 127 ACLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACG 186
Query: 212 ALLLPLVLPGDPP-APPRSPLAALGLSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHAL 270
ALL P L DP PR+ L SL F + + L+ GYF+PY+HL H
Sbjct: 187 ALLRPPSLAEDPAVGGPRAQLT----SLLHHGPFLRYTVALTLINTGYFIPYLHLVAHLQ 242
Query: 271 DRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTGLGLWVVGLVP 330
D AA +++V A+ D R+V GWL D P+ RLL ++ LTG+ L L P
Sbjct: 243 DLDWDPLPAAFLLSVVAISDLVGRVVSGWLGDAVPGPVTRLLMLWTTLTGVSL---ALFP 299
Query: 331 VVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATGLVMMLMSLGGLL 390
V + L+A AVAYG ++G+ APL F VLP L+G + GL+ M+ S+GGLL
Sbjct: 300 VAQAPTA----LVALAVAYGFTSGALAPLAFSVLPELIGTRRIYCGLGLLQMIESIGGLL 355
Query: 391 GPPLSGFLRDETGDFTASFLLSGSLILSGSFIYIGLP 427
GPPLSG+LRD TG++TASF+++G+ +LSGS I + LP
Sbjct: 356 GPPLSGYLRDVTGNYTASFVVAGAFLLSGSGILLTLP 392
>gi|114796626 solute carrier family 16, member 8 [Homo sapiens]
Length = 504
Score = 256 bits (655), Expect = 2e-68
Identities = 167/438 (38%), Positives = 223/438 (50%), Gaps = 36/438 (8%)
Query: 31 GPPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQA 90
GPPDGGWGWVV A F + G +YG +++ + F L FD DTAW+S++ LA+
Sbjct: 11 GPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSIMLAMLYG 70
Query: 91 ASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPA 150
PV S L TR+G RPV++ GG+LAS G + ++FA+ LL LYL G+L G G AL F P+
Sbjct: 71 TGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPS 130
Query: 151 LGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPC 210
L L YF RRR LA GLA G+ L+P Q LL+ FGWRG LLLG + LH C
Sbjct: 131 LIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCAC 190
Query: 211 GALLLPLVLPGDPP-----------APPRSPLAALGLSL------------------FTR 241
GA++ P PG P AP + GL L T
Sbjct: 191 GAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRRRLLDLAVCTD 250
Query: 242 RAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLA 301
RAF+++A+ L+ G FVP + L +A D G+ AA ++++ D AR CG LA
Sbjct: 251 RAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDIVARPACGALA 310
Query: 302 DQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVF 361
L RL L L L GL + G L+A VA+GLS G L F
Sbjct: 311 G-----LARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMVGALQF 365
Query: 362 GVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGS-LILSGS 420
VL VG A GLV+++ + L+GPP +G L D ++ F L+GS + L+G
Sbjct: 366 EVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEVALAGV 425
Query: 421 FIYIGLPRALPSCGPASP 438
F+ + L C A+P
Sbjct: 426 FMAVATNCCL-RCAKAAP 442
>gi|109288010 solute carrier family 16, member 3 [Homo sapiens]
Length = 465
Score = 249 bits (637), Expect = 3e-66
Identities = 146/399 (36%), Positives = 217/399 (54%), Gaps = 6/399 (1%)
Query: 27 PQPAGPPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALA 86
P PDGGWGW V F I G SY +++ + F +L + F DTAWIS++ LA
Sbjct: 10 PTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLA 69
Query: 87 VQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALV 146
+ P+ S R+G RPV++VGG+ ASLG V ++F ++ +YL G++ G G AL
Sbjct: 70 MLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALN 129
Query: 147 FAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLH 206
F P+L L+RYFS+RR +A GLA G+ L+P QLL D +GWRG L+LG + L+
Sbjct: 130 FQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLN 189
Query: 207 LTPCGALLLPLVLPGDP-PAPPRSPLAALGLSLFTRRAFSIFALGTALVGGGYFVPYVHL 265
C AL+ PLV+ P PPR L LS+F R F ++A+ +++ G FVP V +
Sbjct: 190 CCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFV 249
Query: 266 APHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTGLGLWV 325
+A D G+ AA ++ + D AR G++A G V R +V+ L ++
Sbjct: 250 VSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKV---RPYSVY--LFSFSMFF 304
Query: 326 VGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATGLVMMLMS 385
GL + G G L+ + +G+S G L F VL +VG A GLV+++ +
Sbjct: 305 NGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEA 364
Query: 386 LGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGSFIYI 424
+ L+GPP G L D T + F+L+G+ +L+ S I +
Sbjct: 365 VAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILL 403
>gi|109288012 solute carrier family 16, member 3 [Homo sapiens]
Length = 465
Score = 249 bits (637), Expect = 3e-66
Identities = 146/399 (36%), Positives = 217/399 (54%), Gaps = 6/399 (1%)
Query: 27 PQPAGPPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALA 86
P PDGGWGW V F I G SY +++ + F +L + F DTAWIS++ LA
Sbjct: 10 PTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLA 69
Query: 87 VQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALV 146
+ P+ S R+G RPV++VGG+ ASLG V ++F ++ +YL G++ G G AL
Sbjct: 70 MLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALN 129
Query: 147 FAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLH 206
F P+L L+RYFS+RR +A GLA G+ L+P QLL D +GWRG L+LG + L+
Sbjct: 130 FQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLN 189
Query: 207 LTPCGALLLPLVLPGDP-PAPPRSPLAALGLSLFTRRAFSIFALGTALVGGGYFVPYVHL 265
C AL+ PLV+ P PPR L LS+F R F ++A+ +++ G FVP V +
Sbjct: 190 CCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFV 249
Query: 266 APHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTGLGLWV 325
+A D G+ AA ++ + D AR G++A G V R +V+ L ++
Sbjct: 250 VSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKV---RPYSVY--LFSFSMFF 304
Query: 326 VGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATGLVMMLMS 385
GL + G G L+ + +G+S G L F VL +VG A GLV+++ +
Sbjct: 305 NGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEA 364
Query: 386 LGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGSFIYI 424
+ L+GPP G L D T + F+L+G+ +L+ S I +
Sbjct: 365 VAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILL 403
>gi|4759112 solute carrier family 16, member 3 [Homo sapiens]
Length = 465
Score = 249 bits (637), Expect = 3e-66
Identities = 146/399 (36%), Positives = 217/399 (54%), Gaps = 6/399 (1%)
Query: 27 PQPAGPPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALA 86
P PDGGWGW V F I G SY +++ + F +L + F DTAWIS++ LA
Sbjct: 10 PTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLA 69
Query: 87 VQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALV 146
+ P+ S R+G RPV++VGG+ ASLG V ++F ++ +YL G++ G G AL
Sbjct: 70 MLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALN 129
Query: 147 FAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLH 206
F P+L L+RYFS+RR +A GLA G+ L+P QLL D +GWRG L+LG + L+
Sbjct: 130 FQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLN 189
Query: 207 LTPCGALLLPLVLPGDP-PAPPRSPLAALGLSLFTRRAFSIFALGTALVGGGYFVPYVHL 265
C AL+ PLV+ P PPR L LS+F R F ++A+ +++ G FVP V +
Sbjct: 190 CCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFV 249
Query: 266 APHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTGLGLWV 325
+A D G+ AA ++ + D AR G++A G V R +V+ L ++
Sbjct: 250 VSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKV---RPYSVY--LFSFSMFF 304
Query: 326 VGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATGLVMMLMS 385
GL + G G L+ + +G+S G L F VL +VG A GLV+++ +
Sbjct: 305 NGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEA 364
Query: 386 LGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGSFIYI 424
+ L+GPP G L D T + F+L+G+ +L+ S I +
Sbjct: 365 VAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILL 403
>gi|24431958 solute carrier family 16, member 7 [Homo sapiens]
Length = 478
Score = 234 bits (596), Expect = 2e-61
Identities = 145/424 (34%), Positives = 222/424 (52%), Gaps = 34/424 (8%)
Query: 25 MTPQPAGPP-----DGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAW 79
M P P+ PP DGGWGW+V AAF G SY +++ + F ++ + F + + AW
Sbjct: 1 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW 60
Query: 80 ISALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLA 139
IS++ LAV A PV S L ++G+RPVV+ GG+L LG V ++F+S ++ LYL +G +
Sbjct: 61 ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT 120
Query: 140 GFGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLL 199
G G A PAL + +YF R+R +A GLA+ G+ LAP Q L +TFGW+G+ L+
Sbjct: 121 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI 180
Query: 200 LGAITLHLTPCGALLLPLVLPGDPPAPPRSPLAA-----------------------LGL 236
LG++ L+ G+L+ PL P + ++ L
Sbjct: 181 LGSLLLNACVAGSLMRPLG-PNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDF 239
Query: 237 SLFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLV 296
SLF R F I+ G ++ G+F P + LAP+A D+G+ Y AA +++V A D AR
Sbjct: 240 SLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPS 299
Query: 297 CGWLADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSY 356
G +A+ ++ PR+ F L P+ S L+ AV +GL GS
Sbjct: 300 VGLIANSKYI-RPRIQYFFSFAIMFNGVCHLLCPLAQDYTS----LVLYAVFFGLGFGSV 354
Query: 357 APLVFGVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGSLI 416
+ ++F L LVG A GLV ++ LLGPPL+G L D TG++ ++ G+++
Sbjct: 355 SSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIV 414
Query: 417 LSGS 420
++ S
Sbjct: 415 VAAS 418
>gi|157041233 solute carrier family 16 (monocarboxylic acid
transporters), member 12 [Homo sapiens]
Length = 486
Score = 228 bits (582), Expect = 7e-60
Identities = 140/430 (32%), Positives = 225/430 (52%), Gaps = 39/430 (9%)
Query: 32 PPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQAA 91
PPDGGWGW++ A F + + + R + + F + +F + TAWI ++ V
Sbjct: 12 PPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCVTMLC 71
Query: 92 SPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPAL 151
+P+GS +S + +M+GG+LAS G + S+FA+ L HLYL LG+L G G+AL ++PA+
Sbjct: 72 APLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAI 131
Query: 152 GTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCG 211
+ +YFSRR+ LA G+A++G+G + +LAP +QLL++ F WRGALL+LG L+L CG
Sbjct: 132 AMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCG 191
Query: 212 ALLLPLVLPGDPPAPPR--------------SPLAAL---------------GLSLFTRR 242
AL+ P+ L D P + SP ++L S
Sbjct: 192 ALMRPITLKEDHTTPEQNHVCRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLMS 251
Query: 243 AFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLAD 302
F + A+ + G +V+L P+AL G+ AA ++++ + D + GWL D
Sbjct: 252 DFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITFGWLTD 311
Query: 303 QGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAA-AVAYGLSAGSYAPLVF 361
+ + + + A+ GL + L P++ PLL + +G G+Y L+
Sbjct: 312 RRCLKNYQYVCYLFAVGMDGLCYLCL-PMLQSL-----PLLVPFSCTFGYFDGAYVTLIP 365
Query: 362 GVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSG-SLILSGS 420
V +VG + A G+V L ++ L+ PP++G L D TG +TA+FLL G S+I S
Sbjct: 366 VVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSS- 424
Query: 421 FIYIGLPRAL 430
+ +G R +
Sbjct: 425 -VLLGFARLI 433
>gi|4759116 solute carrier family 16, member 5 [Homo sapiens]
Length = 505
Score = 200 bits (509), Expect = 2e-51
Identities = 141/420 (33%), Positives = 200/420 (47%), Gaps = 30/420 (7%)
Query: 27 PQPAGPPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALA 86
PQ DG W WVV A GL+ G +G+ F +L F S +T+W ++ A
Sbjct: 2 PQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILTA 61
Query: 87 VQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALV 146
V A P+ S L R+G R VM+GGVLASLG V S+F+ +L LY G + G G
Sbjct: 62 VLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFS 121
Query: 147 FAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLH 206
F ++ L YF RRRVLA LA G L + LL+ GWRG L+ G I LH
Sbjct: 122 FQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLH 181
Query: 207 LTPCGALLLPL---VLPGD---PPAPPRSP----LAALGLSLFTRRAFSI---------F 247
CGA++ P+ V P PP PP +P LAA G ++ AF I +
Sbjct: 182 CCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVY 241
Query: 248 ALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVP 307
LG G+ +P V L P+A+ + AAL++++ + R + G +A +
Sbjct: 242 ILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGR---- 297
Query: 308 LPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGL 367
P + L L L + GL +V L+ +AY +S L+F VL +
Sbjct: 298 -PAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDI 356
Query: 368 VGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDF------TASFLLSGSLILSGSF 421
V + +A GL +L L L+ PPL+G L D T +F ++ FL+S +L + GSF
Sbjct: 357 VPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSF 416
>gi|115583685 solute carrier family 16, member 1 [Homo sapiens]
Length = 500
Score = 190 bits (483), Expect = 2e-48
Identities = 129/434 (29%), Positives = 206/434 (47%), Gaps = 44/434 (10%)
Query: 32 PPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQAA 91
PPDGGWGW V AF G SY +S+ + F ++ F + + +WIS++ LAV
Sbjct: 13 PPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGG 72
Query: 92 SPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPAL 151
P+ S L ++G+R V++VGG L+ G + ++F + + LY+ +G++ G G A PAL
Sbjct: 73 GPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPAL 132
Query: 152 GTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCG 211
+ +YF +RR LA GLA+ G+ LAP Q+ FGWRG+ L+LG + L+ G
Sbjct: 133 TMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAG 192
Query: 212 ALLLPL----------------------------------VLPGDPPAPPRSPLAA---- 233
AL+ P+ ++ P RS
Sbjct: 193 ALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQTINQF 252
Query: 234 LGLSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGA 293
L L+LFT R F ++ G ++ G F P V L+ + + +A ++++ A D A
Sbjct: 253 LDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVA 312
Query: 294 RLVCGWLADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSA 353
R G +A+ + PR+ F A + G+ ++ + A +G +
Sbjct: 313 RPSMGLVANTKPI-RPRIQYFFAA----SVVANGVCHMLAPLSTTYVGFCVYAGFFGFAF 367
Query: 354 GSYAPLVFGVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSG 413
G + ++F L LVG A GLV ++ LLGPPL G L D GD+ ++ G
Sbjct: 368 GWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACG 427
Query: 414 -SLILSGSFIYIGL 426
LI+SG +++IG+
Sbjct: 428 VVLIISGIYLFIGM 441
>gi|18699730 solute carrier family 16, member 10 [Homo sapiens]
Length = 515
Score = 177 bits (450), Expect = 1e-44
Identities = 122/424 (28%), Positives = 199/424 (46%), Gaps = 23/424 (5%)
Query: 21 PQTAMTPQPAGPPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHF-----DRSAQ 75
P TA +P PP+GGWGW+V AA NG +G+ + G+ F + E F D+
Sbjct: 53 PATAEPHEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVF 112
Query: 76 DTAWISALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGL 135
TAW+ +L++ + P+ S + +G R +VG + +G + S+F S + LYL
Sbjct: 113 KTAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTY 172
Query: 136 GLLAGFGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRG 195
G++ G + + P+L L YF +R L G+ G+ ++LL L++L+D+ G
Sbjct: 173 GIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFY 232
Query: 196 ALLLLGAITLHLTPCGALLLPLVLPGDPPAPPRS------------PLAALGLSLFTRRA 243
L +L L G PL S P ++F A
Sbjct: 233 TLRVLCIFMFVLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIFNFAIFKVTA 292
Query: 244 FSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQ 303
++++A+G L GYFVPYVHL H +R +V+ + RL+ G +AD
Sbjct: 293 YAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGRIADY 352
Query: 304 GWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGV 363
+P + V+ L L + +GL+ ++ S G L+A + GL G + ++ +
Sbjct: 353 ----VPGVKKVY--LQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPI 406
Query: 364 LPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGSFIY 423
LVG V QA G ++ MS+ +GPP++G LRD+ G + +F L+G L G +
Sbjct: 407 AFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVL 466
Query: 424 IGLP 427
+P
Sbjct: 467 CFIP 470
>gi|169217968 PREDICTED: similar to solute carrier family 16, member
5 [Homo sapiens]
Length = 453
Score = 158 bits (400), Expect = 9e-39
Identities = 119/354 (33%), Positives = 170/354 (48%), Gaps = 30/354 (8%)
Query: 93 PVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPALG 152
P+ S L R+G R VM+GGVLASLG V S+F+ +L LY G + G G F ++
Sbjct: 16 PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSIT 75
Query: 153 TLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGA 212
L YF RRRVLA LA G L + LL+ GWRG L+ G I LH CGA
Sbjct: 76 VLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGA 135
Query: 213 LLLPL---VLPGD---PPAPPRSP----LAALGLSLFTRRAFSI---------FALGTAL 253
++ P+ V P PP PP +P LAA G ++ AF I + LG
Sbjct: 136 IIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMW 195
Query: 254 VGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLA 313
G+ +P V L P+A+ + AAL++++ + R + G +A + P +
Sbjct: 196 SVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGR-----PAFAS 250
Query: 314 VFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGV 373
L L L + GL +V L+ +AY +S L+F VL +V +
Sbjct: 251 HRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQF 310
Query: 374 VQATGLVMMLMSLGGLLGPPLSGFLRDETGDF------TASFLLSGSLILSGSF 421
+A GL +L L L+ PPL+G L D T +F ++ FL+S +L + GSF
Sbjct: 311 PRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSF 364
>gi|40789261 solute carrier family 16, member 6 [Homo sapiens]
Length = 523
Score = 156 bits (394), Expect = 4e-38
Identities = 73/196 (37%), Positives = 122/196 (62%), Gaps = 2/196 (1%)
Query: 33 PDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQAAS 92
PDGGWGW VA + F + +YG++++ G+ F DL + F+ S +WI ++ + V ++
Sbjct: 19 PDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISICVFVLTFSA 78
Query: 93 PVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPALG 152
P+ + LS R+G R VVM+GG+L S G V ++F+ ++ H+Y+ +G+++G G+ F P +
Sbjct: 79 PLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVT 138
Query: 153 TLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGA 212
LS+YF +RR + +A TG + APA+ L + GWR +LL +G + L++ GA
Sbjct: 139 ILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGA 198
Query: 213 LLLPLVLPGDPPAPPR 228
LL P+ + G PA P+
Sbjct: 199 LLRPIFIRG--PASPK 212
>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
Length = 613
Score = 154 bits (388), Expect = 2e-37
Identities = 129/458 (28%), Positives = 200/458 (43%), Gaps = 33/458 (7%)
Query: 19 PTPQTAMTPQPAGPPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDT- 77
PT +T T + PP+GG+GWVV AA NG +G+ S+G+ + L E +
Sbjct: 155 PTVETRGTARGFQPPEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVE 214
Query: 78 ---AWISALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLG 134
AW+ ALA+ + SP+ S + R G R G +A +G S+F S L Y
Sbjct: 215 FQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFT 274
Query: 135 LGLLAGFGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWR 194
G+L G G + F P+L L YF RR LA G+ G+ S+ +++L D
Sbjct: 275 YGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIKLA 334
Query: 195 GALLLLGAITLHLTPCGALLLPLVLPGDPPAPPRSPLAAL------------GLSLFTRR 242
+L L PL LP P + + L + +F +R
Sbjct: 335 QTFQVLSTFMFVLMLLSLTYRPL-LPSSQDTPSKRGVRTLHQRFLAQLRKYFNMRVFRQR 393
Query: 243 AFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAG-ARLVCGWLA 301
+ I+A G A GYFVPYVHL + ++ V+ V +G RLV G ++
Sbjct: 394 TYRIWAFGIAAAALGYFVPYVHLMKY-VEEEFSEIKETWVLLVCIGATSGLGRLVSGHIS 452
Query: 302 DQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVF 361
D +P L ++ L L ++GL+ ++ G L+ + GL G + ++
Sbjct: 453 DS----IPGLKKIY--LQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMA 506
Query: 362 GVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGSF 421
+ LVG QA G ++ +M+L + GPP++G LR+ GD+ +F +G + G+
Sbjct: 507 PIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAV 566
Query: 422 IYIGLP--------RALPSCGPASPPATPPPETGELLP 451
I +P + A P GELLP
Sbjct: 567 ILFFVPLMHQRMFKKEQRDSSKDKMLAPDPDPNGELLP 604
>gi|41327156 solute carrier family 16 (monocarboxylic acid
transporters), member 14 [Homo sapiens]
Length = 510
Score = 144 bits (364), Expect = 1e-34
Identities = 74/207 (35%), Positives = 120/207 (57%), Gaps = 1/207 (0%)
Query: 21 PQTAMTPQPAGPPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWI 80
P+ T +P DGGW W++ ++F ++ L G +LG+ + E F +S TAW+
Sbjct: 16 PKDKKTLKPHPNIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWV 75
Query: 81 SALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAG 140
S+L++ + P G R ++GG++ SLG+V SA+A+++ +L++ G+ AG
Sbjct: 76 SSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAG 135
Query: 141 FGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLL 200
G + + PA+ + RYF +RR LA GL+ TG G + L+ L+ L +GWR A+L+
Sbjct: 136 LGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQ 195
Query: 201 GAITLHLTPCGALLLPLVLPGDPPAPP 227
GA++L+L CGAL+ PL PG P P
Sbjct: 196 GAVSLNLCVCGALMRPL-SPGKNPNDP 221
Score = 55.1 bits (131), Expect = 1e-07
Identities = 43/184 (23%), Positives = 78/184 (42%), Gaps = 9/184 (4%)
Query: 237 SLFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAAL-VVAVAAMGDAGARL 295
SLFT R F F + +P++HL L + ++ A+ ++
Sbjct: 309 SLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVNLYNLSEQNDVFPLTSIIAIVHIFGKV 368
Query: 296 VCGWLADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGS 355
+ G +AD + + + + L ++++ L+ G L G S+G
Sbjct: 369 ILGVIADLPCISVWNVFLLANFTLVLSIFILPLMHTYAG-------LAVICALIGFSSG- 420
Query: 356 YAPLVFGVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGSL 415
Y L+ V LVG+ + A G+++ + LLGPP +G++ D T + SF + G L
Sbjct: 421 YFSLMPVVTEDLVGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYICGLL 480
Query: 416 ILSG 419
+ G
Sbjct: 481 YMIG 484
Score = 35.8 bits (81), Expect = 0.086
Identities = 32/117 (27%), Positives = 48/117 (41%), Gaps = 28/117 (23%)
Query: 113 VLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPALGTLSRYFSRRRVL-------- 164
+LA+ V S F L+H Y GL ++ +G S YFS V+
Sbjct: 386 LLANFTLVLSIFILPLMHTYAGLAVICAL---------IGFSSGYFSLMPVVTEDLVGIE 436
Query: 165 ----AVGLALTGNGASSLLLAPALQLLLD-------TFGWRGALLLLGAITLHLTPC 210
A G+ + NG S+LL P + D +F G L ++G + L + PC
Sbjct: 437 HLANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYICGLLYMIGILFLLIQPC 493
>gi|34916028 solute carrier family 16 (monocarboxylic acid
transporters), member 9 [Homo sapiens]
Length = 509
Score = 131 bits (329), Expect = 2e-30
Identities = 67/196 (34%), Positives = 109/196 (55%), Gaps = 1/196 (0%)
Query: 33 PDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQAAS 92
PDGGWGWV+ +F L YG ++G+ + + + F TAW+ +LA V AS
Sbjct: 7 PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLAS 66
Query: 93 PVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPALG 152
PV S + +GARPV + G + + G + S+FA ++ L+ G++ G G L++ +
Sbjct: 67 PVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVT 126
Query: 153 TLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGA 212
+YF RR LA+GL TG+ + A ++L++ +G G LL++GA+ L++ CG+
Sbjct: 127 ITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGS 186
Query: 213 LLLPLVLPGDPPAPPR 228
L+ PL D P P +
Sbjct: 187 LMRPL-QSSDCPLPKK 201
Score = 54.3 bits (129), Expect = 2e-07
Identities = 54/211 (25%), Positives = 89/211 (42%), Gaps = 14/211 (6%)
Query: 236 LSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAAL-VVAVAAMGDAGAR 294
++LF + FS + L G F P + + A + + ++++ + A +
Sbjct: 298 VALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGK 357
Query: 295 LVCGWLADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAG 354
L+ G LAD W+ L + GL L + +S+ L + + G G
Sbjct: 358 LLLGILADFKWINTLYLYVATLIIMGLALCAIPFA------KSYVTLALLSGIL-GFLTG 410
Query: 355 SYAPLVFGVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGS 414
+++ + V VG+ + A G++M LG LGPP+ G+ D T + +F SG
Sbjct: 411 NWSIFPY-VTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGF 469
Query: 415 LILSGSFIYIGLPRALPS---CGPASPPATP 442
+L G FI L ALPS C P P
Sbjct: 470 CVLLGGFIL--LLAALPSWDTCNKQLPKPAP 498
>gi|4759114 solute carrier family 16, member 4 [Homo sapiens]
Length = 487
Score = 114 bits (285), Expect = 2e-25
Identities = 56/184 (30%), Positives = 103/184 (55%), Gaps = 1/184 (0%)
Query: 34 DGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQAASP 93
DGGWGW++ F +N G+ ++ + F E F+ +++ WI ++ +++ A P
Sbjct: 16 DGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAGP 75
Query: 94 VGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPALGT 153
+ + + G + ++G + + G++ S++A+ + L + +GLL G G A ++ A
Sbjct: 76 LVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVV 135
Query: 154 LSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGAL 213
++YF +R L+ +A +G G + LLAP + L+D + W GAL+L GAI L+L P L
Sbjct: 136 TTKYFKKRLALSTAIARSGMGL-TFLLAPFTKFLIDLYDWTGALILFGAIALNLVPSSML 194
Query: 214 LLPL 217
L P+
Sbjct: 195 LRPI 198
Score = 78.2 bits (191), Expect = 2e-14
Identities = 56/195 (28%), Positives = 85/195 (43%), Gaps = 9/195 (4%)
Query: 236 LSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARL 295
+SLF F IF L YF+P HL A G+ A+ +V+VA + + +++
Sbjct: 293 ISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQI 352
Query: 296 VCGWLADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAA-AVAYGLSAG 354
+ GW+ADQ W+ + L G+ + L PLL + + + AG
Sbjct: 353 ISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTF--------PLLMTYTICFAIFAG 404
Query: 355 SYAPLVFGVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGS 414
Y L+ VL L V + GL + L GPP++G+L D T + SF SG
Sbjct: 405 GYLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGI 464
Query: 415 LILSGSFIYIGLPRA 429
L S + +P A
Sbjct: 465 CYLLSSVSFFFVPLA 479
>gi|16445357 hypothetical protein LOC116843 [Homo sapiens]
Length = 456
Score = 57.0 bits (136), Expect = 4e-08
Identities = 109/426 (25%), Positives = 167/426 (39%), Gaps = 43/426 (10%)
Query: 21 PQTAMTPQPAGPPDGGWGWV------VAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSA 74
P+ PAG GW+ V +A ++N S LG FP AE S
Sbjct: 10 PRAPGGDDPAGSAGETPGWLSREQVFVLISAASVNLGSMMCYSILGPFFPKEAEKKGASN 69
Query: 75 QDTAWISALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLH---L 131
I + AS V GA+ + V G+ S G D + +
Sbjct: 70 TIIGMIFGCFALFELLASLVFGNYLVHIGAK-FMFVAGMFVSGGVTILFGVLDRVPDGPV 128
Query: 132 YLGLGLLAGFGWALVFAPAL----GTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLL 187
++ + L A+ FA A+ L++ F +G T +G +L P L
Sbjct: 129 FIAMCFLVRVMDAVSFAAAMTASSSILAKAFPNNVATVLGSLETFSGLGLILGPPVGGFL 188
Query: 188 LDTFGWRGALLLLGAITLHLTPCGALLLPLVL--PGDPPAPPRSPLAALGLSLFTRRAFS 245
+FG+ ++LG + L + P +LP PG+ L +GL AF
Sbjct: 189 YQSFGYEVPFIVLGCVVLLMVPLNMYILPNYESDPGEHSFWKLIALPKVGLI-----AFV 243
Query: 246 IFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGW 305
I +L + G+ P + L GY LV A+ A + + G L+D+
Sbjct: 244 INSLSSCF---GFLDPTLSLFVLEKFNLPAGY-VGLVFLGMALSYAISSPLFGLLSDKR- 298
Query: 306 VPLPRLLAVFGALTGLGLW-VVGLVPVVG-GEESWGGPLLAAAVAYGLSAGSYAPLVF-- 361
PL + L VFG L G + ++G VP++ + W L+ V GLSAG F
Sbjct: 299 PPLRKWLLVFGNLITAGCYMLLGPVPILHIKSQLW--LLVLILVVSGLSAGMSIIPTFPE 356
Query: 362 --------GVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSG 413
G GL +G V +GL + S+G +GP L GFL ++ G A+ +
Sbjct: 357 ILSCAHENGFEEGLSTLGLV---SGLFSAMWSIGAFMGPTLGGFLYEKIGFEWAAAIQGL 413
Query: 414 SLILSG 419
++SG
Sbjct: 414 WALISG 419
Score = 31.2 bits (69), Expect = 2.1
Identities = 16/48 (33%), Positives = 26/48 (54%)
Query: 378 GLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGSFIYIG 425
GLV + M+L + PL G L D+ L+ G+LI +G ++ +G
Sbjct: 274 GLVFLGMALSYAISSPLFGLLSDKRPPLRKWLLVFGNLITAGCYMLLG 321
>gi|4503847 solute carrier family 37 (glucose-6-phosphate
transporter), member 4 [Homo sapiens]
Length = 429
Score = 45.4 bits (106), Expect = 1e-04
Identities = 91/405 (22%), Positives = 156/405 (38%), Gaps = 69/405 (17%)
Query: 36 GWGW---VVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQAAS 92
G+G+ V+ +A F L Y ++ P L E D +I++ A +
Sbjct: 5 GYGYYRTVIFSAMFGGYSLYYFNRKTFSFVMPSLVEEIPLDKDDLGFITSSQSAAYAISK 64
Query: 93 PVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPALG 152
V LS + AR + G +L L +F A++S + ++ L L G L + P
Sbjct: 65 FVSGVLSDQMSARWLFSSGLLLVGLVNIFFAWSSTV-PVFAALWFLNGLAQGLGWPPCGK 123
Query: 153 TLSRYFSRRR------VLAVGLALTGNGASSLLLAPALQLLL-DTFGWRGALLLLGAITL 205
L ++F + +L+ + L G L P L +L ++ WR L L GA+ +
Sbjct: 124 VLRKWFEPSQFGTWWAILSTSMNLAGG------LGPILATILAQSYSWRSTLALSGALCV 177
Query: 206 HLTPCGALLL-----PLVLPGDPPAP---------PRSPLAALGLS----LFTRRAFSIF 247
++ LL+ + L P P S L L LS + + +F
Sbjct: 178 VVSFLCLLLIHNEPADVGLRNLDPMPSEGKKGSLKEESTLQELLLSPYLWVLSTGYLVVF 237
Query: 248 ALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWV- 306
+ T G F AL G++ + A+ G G+ + G+L+D+
Sbjct: 238 GVKTCCTDWGQFFLIQEKGQSAL------VGSSYMSALEVGGLVGS-IAAGYLSDRAMAK 290
Query: 307 --------PLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAP 358
P LL A + +++ + + W +L +G S SY P
Sbjct: 291 AGLSNYGNPRHGLLLFMMAGMTVSMYLFRVTVTSDSPKLW---ILVLGAVFGFS--SYGP 345
Query: 359 L-VFGVL------PGLVGVGGVVQATGLVMMLMSLGGLL-GPPLS 395
+ +FGV+ P L G + +V ++ ++GG L G P S
Sbjct: 346 IALFGVIANESAPPNLCGT-----SHAIVGLMANVGGFLAGLPFS 385
>gi|154350196 vesicular nucleotide transporter SLC17A9 [Homo
sapiens]
Length = 436
Score = 41.6 bits (96), Expect = 0.002
Identities = 80/346 (23%), Positives = 137/346 (39%), Gaps = 46/346 (13%)
Query: 94 VGSALSTRWGARPVVMVGG--------VLASLGFVFSAFASDLLHLYLGLGLLAGFGWAL 145
VG L R G V+++ V L + SA + + + +GLL G
Sbjct: 79 VGGHLGDRIGGEKVILLSASAWGSITAVTPLLAHLSSAHLAFMTFSRILMGLLQG----- 133
Query: 146 VFAPALGTLSRYFSRRRVLAVGLALTGNGAS--SLLLAPALQLLLDTFGWRGALLLLGAI 203
V+ PAL +L R A ++ G G+ +LL LLL+ +GW+ G +
Sbjct: 134 VYFPALTSLLSQKVRESERAFTYSIVGAGSQFGTLLTGAVGSLLLEWYGWQSIFYFSGGL 193
Query: 204 TL--------HLTPCGALLLPL-VLPGDPPAPPRSPLAALGLSLFTRRAFSIFALGTALV 254
TL +L L+L L VL P S + LF + A +
Sbjct: 194 TLLWVWYVYRYLLSEKDLILALGVLAQSRPVSRHSRVP--WRRLFRKPAVWAAVVSQLSA 251
Query: 255 GGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLAD----QGWVPLPR 310
+F+ + P + + V + A L G+L+D QG+ R
Sbjct: 252 ACSFFI-LLSWLPTFFEETFPDAKGWIFNVVPWLVAIPASLFSGFLSDHLINQGY----R 306
Query: 311 LLAVFGALTGLGLWVVGLVPV-VGGEESWGGPLLAAAVAYGLSAGSYAPL---VFGVLPG 366
+ V + G+GL + + + +G S+ ++ A+ + GL +++ + + + P
Sbjct: 307 AITVRKLMQGMGLGLSSVFALCLGHTSSFCESVVFASASIGLQTFNHSGISVNIQDLAPS 366
Query: 367 LVG-VGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLL 411
G + GV G +L G++G L G+L + TG +T F L
Sbjct: 367 CAGFLFGVANTAG------ALAGVVGVCLGGYLMETTGSWTCLFNL 406
>gi|126352608 elastin isoform e precursor [Homo sapiens]
Length = 705
Score = 37.0 bits (84), Expect = 0.039
Identities = 44/133 (33%), Positives = 51/133 (38%), Gaps = 19/133 (14%)
Query: 256 GGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVF 315
GGY +PY L G G G A A G AG G + A F
Sbjct: 215 GGYGLPYT---TGKLPYGYGPGGVA-----GAAGKAGYPTGTGVGPQAAAAAAAKAAAKF 266
Query: 316 GA-----LTGLG----LWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPG 366
GA L G+G V G +P +GG G P AAA A A Y G++PG
Sbjct: 267 GAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAA-GLVPG 325
Query: 367 LVGVG-GVVQATG 378
G G GVV G
Sbjct: 326 GPGFGPGVVGVPG 338
Score = 32.7 bits (73), Expect = 0.73
Identities = 72/274 (26%), Positives = 95/274 (34%), Gaps = 46/274 (16%)
Query: 42 AAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQAASPVGSALSTR 101
A AA A YGL+ +G+A P + A + LA +P G ++
Sbjct: 441 AQAAAAAKAAKYGLVPGVGVA-PGVGV-----APGVGVAPGVGLAPGVGVAP-GVGVAPG 493
Query: 102 WGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGL-LAGFGWALVFAPALGTLSRYFSR 160
G P + GGV A+ A L GLG + G G V P LG +
Sbjct: 494 VGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVG-VGVPGLGVGAGVPG- 551
Query: 161 RRVLAVGLALTGNGA--SSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPLV 218
L VG + G GA +L A A + G G L LG + + GA
Sbjct: 552 ---LGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGA------ 602
Query: 219 LPGDPPAPPRSPLAALGLSLFTRRAFSIFALGTALVGG----GYFVPYVHLAPHALDRGL 274
P AA + +A +G A +GG G VP G+
Sbjct: 603 ----------GPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVP-----------GV 641
Query: 275 GGYGAALVVAVAAMGDAGARLVCGWLADQGWVPL 308
GG G A A GA + G L G PL
Sbjct: 642 GGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPL 675
Score = 32.0 bits (71), Expect = 1.2
Identities = 43/134 (32%), Positives = 54/134 (40%), Gaps = 7/134 (5%)
Query: 248 ALGTALVGGGYFVPYVHLAPHA-LDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWV 306
A G L G P V +AP + G+G G A AA A A+L G
Sbjct: 473 APGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIP 532
Query: 307 PLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPG 366
L + V G G G+ +G+ V G + G L AA A Y V GVL G
Sbjct: 533 GLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAA------KAAKYGAAVPGVLGG 586
Query: 367 LVGVGGVVQATGLV 380
L +GGV G+V
Sbjct: 587 LGALGGVGIPGGVV 600
Score = 32.0 bits (71), Expect = 1.2
Identities = 55/197 (27%), Positives = 73/197 (37%), Gaps = 37/197 (18%)
Query: 211 GALLLPLVLPGDPPAPPRSPLAALGLSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHAL 270
G + P + PG A +S AA + RA + G +G G VP L
Sbjct: 493 GVGVAPGIGPGGVAAAAKS--AAKVAAKAQLRAAAGLGAGIPGLGVGVGVP-------GL 543
Query: 271 DRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTGLGL--WVVGL 328
G G G + V G L A G +P +L GAL G+G+ VVG
Sbjct: 544 GVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG-AAVPGVLGGLGALGGVGIPGGVVG- 601
Query: 329 VPVVGGEESWGGPLLAAAVAYGLSAGSYAPLV-------FGV----LPGLVGVGGVVQAT 377
GP AAA A + + LV GV +PG+ G+GG+ A
Sbjct: 602 ----------AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAA 651
Query: 378 GLVMM---LMSLGGLLG 391
LGG+LG
Sbjct: 652 AAKAAKYGAAGLGGVLG 668
Score = 29.3 bits (64), Expect = 8.1
Identities = 63/242 (26%), Positives = 79/242 (32%), Gaps = 38/242 (15%)
Query: 171 TGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPLVLPGDPPAPPRSP 230
TG G A A FG A +L G + G +P +PG
Sbjct: 246 TGTGVGPQAAAAAAAKAAAKFGAGAAGVLPG-----VGGAGVPGVPGAIPGIGGIAGVGT 300
Query: 231 LAALGLSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAAL--------- 281
AA + +A A + GG F P V P A G+G GA +
Sbjct: 301 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 360
Query: 282 ------VVAVAAMGDAGARLV-CGWLADQGWVPLPRLLAVFGALTGLGLWVVGL-----V 329
VV+ A A A+ G G +P G G G+ V G+ V
Sbjct: 361 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 420
Query: 330 PVVGGEESWGG------------PLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQAT 377
P VGG GG A A YGL G GV PG+ GV A
Sbjct: 421 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAP 480
Query: 378 GL 379
G+
Sbjct: 481 GV 482
>gi|126352446 elastin isoform d precursor [Homo sapiens]
Length = 711
Score = 37.0 bits (84), Expect = 0.039
Identities = 44/133 (33%), Positives = 51/133 (38%), Gaps = 19/133 (14%)
Query: 256 GGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVF 315
GGY +PY L G G G A A G AG G + A F
Sbjct: 220 GGYGLPYT---TGKLPYGYGPGGVA-----GAAGKAGYPTGTGVGPQAAAAAAAKAAAKF 271
Query: 316 GA-----LTGLG----LWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPG 366
GA L G+G V G +P +GG G P AAA A A Y G++PG
Sbjct: 272 GAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAA-GLVPG 330
Query: 367 LVGVG-GVVQATG 378
G G GVV G
Sbjct: 331 GPGFGPGVVGVPG 343
Score = 33.9 bits (76), Expect = 0.33
Identities = 78/300 (26%), Positives = 111/300 (37%), Gaps = 42/300 (14%)
Query: 81 SALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAG 140
+A+ V A+ +A + ++GARP V VGG+ + A +G+G + G
Sbjct: 367 AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPT-----YGVGAGGFPGFGVGVGGIPG 421
Query: 141 FGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLL 200
+ P +G + V VG++ A++ A A + + T A
Sbjct: 422 ----VAGVPGVGGVPGVGG---VPGVGISPEAQAAAA---AKAAKYGVGTPAAAAAKAAA 471
Query: 201 GAITLHLTPCGALLLPLVLPGDPPAPPRSPLAALGLSLFTRRAFSIFALGTALVGGGYFV 260
A L P V PG AP +GL A G + G
Sbjct: 472 KAAQFGLVPGVG-----VAPGVGVAPGVGVAPGVGL-----------APGVGVAPGVGVA 515
Query: 261 PYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTG 320
P V +AP G+G G A AA A A+L G L + V G G
Sbjct: 516 PGVGVAP-----GIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVG 570
Query: 321 LGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATGLV 380
G+ +G+ V G + G L AA A Y V GVL GL +GGV G+V
Sbjct: 571 AGVPGLGVGAGVPGFGAVPGALAAA------KAAKYGAAVPGVLGGLGALGGVGIPGGVV 624
Score = 31.6 bits (70), Expect = 1.6
Identities = 52/185 (28%), Positives = 69/185 (37%), Gaps = 31/185 (16%)
Query: 211 GALLLPLVLPGDPPAPPRSPLAALGLSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHAL 270
G + P + PG A +S AA + RA + G +G G VP L
Sbjct: 517 GVGVAPGIGPGGVAAAAKS--AAKVAAKAQLRAAAGLGAGIPGLGVGVGVP-------GL 567
Query: 271 DRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTGLGL--WVVGL 328
G G G + V G L A G +P +L GAL G+G+ VVG
Sbjct: 568 GVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG-AAVPGVLGGLGALGGVGIPGGVVG- 625
Query: 329 VPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATGLVMMLMSLGG 388
GP AAA A + + LV G +GVGG + + +GG
Sbjct: 626 ----------AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGG--------LGVPGVGG 667
Query: 389 LLGPP 393
L G P
Sbjct: 668 LGGIP 672
>gi|126352322 elastin isoform c precursor [Homo sapiens]
Length = 692
Score = 37.0 bits (84), Expect = 0.039
Identities = 44/133 (33%), Positives = 51/133 (38%), Gaps = 19/133 (14%)
Query: 256 GGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVF 315
GGY +PY L G G G A A G AG G + A F
Sbjct: 220 GGYGLPYT---TGKLPYGYGPGGVA-----GAAGKAGYPTGTGVGPQAAAAAAAKAAAKF 271
Query: 316 GA-----LTGLG----LWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPG 366
GA L G+G V G +P +GG G P AAA A A Y G++PG
Sbjct: 272 GAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAA-GLVPG 330
Query: 367 LVGVG-GVVQATG 378
G G GVV G
Sbjct: 331 GPGFGPGVVGVPG 343
Score = 32.0 bits (71), Expect = 1.2
Identities = 43/134 (32%), Positives = 54/134 (40%), Gaps = 7/134 (5%)
Query: 248 ALGTALVGGGYFVPYVHLAPHA-LDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWV 306
A G L G P V +AP + G+G G A AA A A+L G
Sbjct: 478 APGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIP 537
Query: 307 PLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPG 366
L + V G G G+ +G+ V G + G L AA A Y V GVL G
Sbjct: 538 GLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAA------KAAKYGAAVPGVLGG 591
Query: 367 LVGVGGVVQATGLV 380
L +GGV G+V
Sbjct: 592 LGALGGVGIPGGVV 605
Score = 31.6 bits (70), Expect = 1.6
Identities = 52/185 (28%), Positives = 69/185 (37%), Gaps = 31/185 (16%)
Query: 211 GALLLPLVLPGDPPAPPRSPLAALGLSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHAL 270
G + P + PG A +S AA + RA + G +G G VP L
Sbjct: 498 GVGVAPGIGPGGVAAAAKS--AAKVAAKAQLRAAAGLGAGIPGLGVGVGVP-------GL 548
Query: 271 DRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTGLGL--WVVGL 328
G G G + V G L A G +P +L GAL G+G+ VVG
Sbjct: 549 GVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG-AAVPGVLGGLGALGGVGIPGGVVG- 606
Query: 329 VPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATGLVMMLMSLGG 388
GP AAA A + + LV G +GVGG + + +GG
Sbjct: 607 ----------AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGG--------LGVPGVGG 648
Query: 389 LLGPP 393
L G P
Sbjct: 649 LGGIP 653
Score = 29.3 bits (64), Expect = 8.1
Identities = 63/242 (26%), Positives = 79/242 (32%), Gaps = 38/242 (15%)
Query: 171 TGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPLVLPGDPPAPPRSP 230
TG G A A FG A +L G + G +P +PG
Sbjct: 251 TGTGVGPQAAAAAAAKAAAKFGAGAAGVLPG-----VGGAGVPGVPGAIPGIGGIAGVGT 305
Query: 231 LAALGLSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAAL--------- 281
AA + +A A + GG F P V P A G+G GA +
Sbjct: 306 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 365
Query: 282 ------VVAVAAMGDAGARLV-CGWLADQGWVPLPRLLAVFGALTGLGLWVVGL-----V 329
VV+ A A A+ G G +P G G G+ V G+ V
Sbjct: 366 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 425
Query: 330 PVVGGEESWGG------------PLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQAT 377
P VGG GG A A YGL G GV PG+ GV A
Sbjct: 426 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAP 485
Query: 378 GL 379
G+
Sbjct: 486 GV 487
>gi|126352700 elastin isoform b precursor [Homo sapiens]
Length = 677
Score = 37.0 bits (84), Expect = 0.039
Identities = 44/133 (33%), Positives = 51/133 (38%), Gaps = 19/133 (14%)
Query: 256 GGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVF 315
GGY +PY L G G G A A G AG G + A F
Sbjct: 205 GGYGLPYT---TGKLPYGYGPGGVA-----GAAGKAGYPTGTGVGPQAAAAAAAKAAAKF 256
Query: 316 GA-----LTGLG----LWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPG 366
GA L G+G V G +P +GG G P AAA A A Y G++PG
Sbjct: 257 GAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAA-GLVPG 315
Query: 367 LVGVG-GVVQATG 378
G G GVV G
Sbjct: 316 GPGFGPGVVGVPG 328
Score = 32.0 bits (71), Expect = 1.2
Identities = 43/134 (32%), Positives = 54/134 (40%), Gaps = 7/134 (5%)
Query: 248 ALGTALVGGGYFVPYVHLAPHA-LDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWV 306
A G L G P V +AP + G+G G A AA A A+L G
Sbjct: 463 APGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIP 522
Query: 307 PLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPG 366
L + V G G G+ +G+ V G + G L AA A Y V GVL G
Sbjct: 523 GLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAA------KAAKYGAAVPGVLGG 576
Query: 367 LVGVGGVVQATGLV 380
L +GGV G+V
Sbjct: 577 LGALGGVGIPGGVV 590
Score = 31.6 bits (70), Expect = 1.6
Identities = 52/185 (28%), Positives = 69/185 (37%), Gaps = 31/185 (16%)
Query: 211 GALLLPLVLPGDPPAPPRSPLAALGLSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHAL 270
G + P + PG A +S AA + RA + G +G G VP L
Sbjct: 483 GVGVAPGIGPGGVAAAAKS--AAKVAAKAQLRAAAGLGAGIPGLGVGVGVP-------GL 533
Query: 271 DRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTGLGL--WVVGL 328
G G G + V G L A G +P +L GAL G+G+ VVG
Sbjct: 534 GVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG-AAVPGVLGGLGALGGVGIPGGVVG- 591
Query: 329 VPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATGLVMMLMSLGG 388
GP AAA A + + LV G +GVGG + + +GG
Sbjct: 592 ----------AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGG--------LGVPGVGG 633
Query: 389 LLGPP 393
L G P
Sbjct: 634 LGGIP 638
Score = 29.3 bits (64), Expect = 8.1
Identities = 63/242 (26%), Positives = 79/242 (32%), Gaps = 38/242 (15%)
Query: 171 TGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPLVLPGDPPAPPRSP 230
TG G A A FG A +L G + G +P +PG
Sbjct: 236 TGTGVGPQAAAAAAAKAAAKFGAGAAGVLPG-----VGGAGVPGVPGAIPGIGGIAGVGT 290
Query: 231 LAALGLSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAAL--------- 281
AA + +A A + GG F P V P A G+G GA +
Sbjct: 291 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 350
Query: 282 ------VVAVAAMGDAGARLV-CGWLADQGWVPLPRLLAVFGALTGLGLWVVGL-----V 329
VV+ A A A+ G G +P G G G+ V G+ V
Sbjct: 351 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 410
Query: 330 PVVGGEESWGG------------PLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQAT 377
P VGG GG A A YGL G GV PG+ GV A
Sbjct: 411 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAP 470
Query: 378 GL 379
G+
Sbjct: 471 GV 472
>gi|126352440 elastin isoform a precursor [Homo sapiens]
Length = 724
Score = 37.0 bits (84), Expect = 0.039
Identities = 44/133 (33%), Positives = 51/133 (38%), Gaps = 19/133 (14%)
Query: 256 GGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVF 315
GGY +PY L G G G A A G AG G + A F
Sbjct: 215 GGYGLPYT---TGKLPYGYGPGGVA-----GAAGKAGYPTGTGVGPQAAAAAAAKAAAKF 266
Query: 316 GA-----LTGLG----LWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPG 366
GA L G+G V G +P +GG G P AAA A A Y G++PG
Sbjct: 267 GAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAA-GLVPG 325
Query: 367 LVGVG-GVVQATG 378
G G GVV G
Sbjct: 326 GPGFGPGVVGVPG 338
Score = 33.9 bits (76), Expect = 0.33
Identities = 78/300 (26%), Positives = 111/300 (37%), Gaps = 42/300 (14%)
Query: 81 SALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAG 140
+A+ V A+ +A + ++GARP V VGG+ + A +G+G + G
Sbjct: 362 AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPT-----YGVGAGGFPGFGVGVGGIPG 416
Query: 141 FGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLL 200
+ P +G + V VG++ A++ A A + + T A
Sbjct: 417 ----VAGVPGVGGVPGVGG---VPGVGISPEAQAAAA---AKAAKYGVGTPAAAAAKAAA 466
Query: 201 GAITLHLTPCGALLLPLVLPGDPPAPPRSPLAALGLSLFTRRAFSIFALGTALVGGGYFV 260
A L P V PG AP +GL A G + G
Sbjct: 467 KAAQFGLVPGVG-----VAPGVGVAPGVGVAPGVGL-----------APGVGVAPGVGVA 510
Query: 261 PYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTG 320
P V +AP G+G G A AA A A+L G L + V G G
Sbjct: 511 PGVGVAP-----GIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVG 565
Query: 321 LGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATGLV 380
G+ +G+ V G + G L AA A Y V GVL GL +GGV G+V
Sbjct: 566 AGVPGLGVGAGVPGFGAVPGALAAA------KAAKYGAAVPGVLGGLGALGGVGIPGGVV 619
Score = 32.0 bits (71), Expect = 1.2
Identities = 55/197 (27%), Positives = 73/197 (37%), Gaps = 37/197 (18%)
Query: 211 GALLLPLVLPGDPPAPPRSPLAALGLSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHAL 270
G + P + PG A +S AA + RA + G +G G VP L
Sbjct: 512 GVGVAPGIGPGGVAAAAKS--AAKVAAKAQLRAAAGLGAGIPGLGVGVGVP-------GL 562
Query: 271 DRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTGLGL--WVVGL 328
G G G + V G L A G +P +L GAL G+G+ VVG
Sbjct: 563 GVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG-AAVPGVLGGLGALGGVGIPGGVVG- 620
Query: 329 VPVVGGEESWGGPLLAAAVAYGLSAGSYAPLV-------FGV----LPGLVGVGGVVQAT 377
GP AAA A + + LV GV +PG+ G+GG+ A
Sbjct: 621 ----------AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAA 670
Query: 378 GLVMM---LMSLGGLLG 391
LGG+LG
Sbjct: 671 AAKAAKYGAAGLGGVLG 687
Score = 31.2 bits (69), Expect = 2.1
Identities = 71/274 (25%), Positives = 95/274 (34%), Gaps = 46/274 (16%)
Query: 42 AAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQAASPVGSALSTR 101
AAA A +GL+ +G+A P + A + LA +P G ++
Sbjct: 460 AAAKAAAKAAQFGLVPGVGVA-PGVGV-----APGVGVAPGVGLAPGVGVAP-GVGVAPG 512
Query: 102 WGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGL-LAGFGWALVFAPALGTLSRYFSR 160
G P + GGV A+ A L GLG + G G V P LG +
Sbjct: 513 VGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVG-VGVPGLGVGAGVPG- 570
Query: 161 RRVLAVGLALTGNGA--SSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPLV 218
L VG + G GA +L A A + G G L LG + + GA
Sbjct: 571 ---LGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGA------ 621
Query: 219 LPGDPPAPPRSPLAALGLSLFTRRAFSIFALGTALVGG----GYFVPYVHLAPHALDRGL 274
P AA + +A +G A +GG G VP G+
Sbjct: 622 ----------GPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVP-----------GV 660
Query: 275 GGYGAALVVAVAAMGDAGARLVCGWLADQGWVPL 308
GG G A A GA + G L G PL
Sbjct: 661 GGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPL 694
>gi|169202389 PREDICTED: similar to mCG50504 [Homo sapiens]
Length = 189
Score = 36.2 bits (82), Expect = 0.066
Identities = 17/36 (47%), Positives = 21/36 (58%), Gaps = 2/36 (5%)
Query: 429 ALPSCGPAS--PPATPPPETGELLPAPQAVLLSPGG 462
A P CGPAS PP +PPP +G PA + +P G
Sbjct: 153 AAPQCGPASAAPPPSPPPRSGTAPPANRTAPATPPG 188
>gi|39753965 hippocampus abundant transcript 1 [Homo sapiens]
Length = 490
Score = 36.2 bits (82), Expect = 0.066
Identities = 22/59 (37%), Positives = 27/59 (45%)
Query: 141 FGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLL 199
F W L+ AP L L F + L GL G S L AP + L D +G + LLL
Sbjct: 49 FAWGLLTAPTLVVLHETFPKHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLLL 107
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 34.7 bits (78), Expect = 0.19
Identities = 16/38 (42%), Positives = 20/38 (52%)
Query: 427 PRALPSCGPASPPATPPPETGELLPAPQAVLLSPGGPG 464
PR + +PP PPP +G P+PQA L PG G
Sbjct: 1106 PRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAG 1143
>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
Length = 744
Score = 34.7 bits (78), Expect = 0.19
Identities = 57/195 (29%), Positives = 70/195 (35%), Gaps = 25/195 (12%)
Query: 271 DRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTGLG-LWVVGLV 329
DRG+GG AL G GA + G + G +P + GA+ G G+V
Sbjct: 361 DRGMGGVPGALGPR-GEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIV 419
Query: 330 PVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATGLVMMLMSLGGL 389
G G P L G P LPG +G G G V L + GL
Sbjct: 420 GPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKG-VPGLPGVPGL 478
Query: 390 LGPPLSGFLRDETGDFTASFLLSGSLILSGSFIYIGLPRALPSCGPASPPATPPPETGEL 449
LGP + E G + G L G G+P GP PP P P+
Sbjct: 479 LGP------KGEPG-------IPGDQGLQGP---PGIPGIGGPSGPIGPPGIPGPKGEPG 522
Query: 450 LPAPQAVLLSPGGPG 464
LP P PG PG
Sbjct: 523 LPGP------PGFPG 531
>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
Length = 744
Score = 34.7 bits (78), Expect = 0.19
Identities = 57/195 (29%), Positives = 70/195 (35%), Gaps = 25/195 (12%)
Query: 271 DRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTGLG-LWVVGLV 329
DRG+GG AL G GA + G + G +P + GA+ G G+V
Sbjct: 361 DRGMGGVPGALGPR-GEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIV 419
Query: 330 PVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATGLVMMLMSLGGL 389
G G P L G P LPG +G G G V L + GL
Sbjct: 420 GPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKG-VPGLPGVPGL 478
Query: 390 LGPPLSGFLRDETGDFTASFLLSGSLILSGSFIYIGLPRALPSCGPASPPATPPPETGEL 449
LGP + E G + G L G G+P GP PP P P+
Sbjct: 479 LGP------KGEPG-------IPGDQGLQGP---PGIPGIGGPSGPIGPPGIPGPKGEPG 522
Query: 450 LPAPQAVLLSPGGPG 464
LP P PG PG
Sbjct: 523 LPGP------PGFPG 531
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.142 0.451
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,149,657
Number of Sequences: 37866
Number of extensions: 1153485
Number of successful extensions: 8610
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 112
Number of HSP's that attempted gapping in prelim test: 8006
Number of HSP's gapped (non-prelim): 632
length of query: 471
length of database: 18,247,518
effective HSP length: 106
effective length of query: 365
effective length of database: 14,233,722
effective search space: 5195308530
effective search space used: 5195308530
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.