BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|23397574 sorting nexin 33 [Homo sapiens] (574 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|23397574 sorting nexin 33 [Homo sapiens] 1174 0.0 gi|157057545 sorting nexin 18 isoform a [Homo sapiens] 587 e-168 gi|224177511 sorting nexin 18 isoform c [Homo sapiens] 499 e-141 gi|157057543 sorting nexin 18 isoform b [Homo sapiens] 499 e-141 gi|7706706 sorting nexin 9 [Homo sapiens] 355 5e-98 gi|153791707 sorting nexin family member 30 [Homo sapiens] 72 2e-12 gi|23943858 sorting nexin 8 [Homo sapiens] 64 3e-10 gi|23111036 sorting nexin 1 isoform c [Homo sapiens] 57 5e-08 gi|19224660 protein kinase C and casein kinase substrate in neur... 55 2e-07 gi|23111034 sorting nexin 1 isoform a [Homo sapiens] 54 4e-07 gi|23111055 sorting nexin 7 isoform b [Homo sapiens] 54 4e-07 gi|194294540 sorting nexin 7 isoform a [Homo sapiens] 54 4e-07 gi|23111038 sorting nexin 2 [Homo sapiens] 54 5e-07 gi|23111032 sorting nexin 1 isoform b [Homo sapiens] 53 9e-07 gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 50 4e-06 gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 50 4e-06 gi|24308229 protein kinase C and casein kinase substrate in neur... 50 4e-06 gi|148747351 protein kinase C and casein kinase substrate in neu... 50 6e-06 gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 49 1e-05 gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 49 1e-05 gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-lik... 49 2e-05 gi|5453710 LIM and SH3 protein 1 [Homo sapiens] 47 6e-05 gi|5453758 nebulette sarcomeric isoform [Homo sapiens] 46 8e-05 gi|47087157 nebulette non-muscle isoform [Homo sapiens] 46 8e-05 gi|38524622 formin binding protein 1 [Homo sapiens] 45 1e-04 gi|171906575 drebrin-like isoform c [Homo sapiens] 45 1e-04 gi|62198235 drebrin-like isoform b [Homo sapiens] 45 1e-04 gi|21361670 drebrin-like isoform a [Homo sapiens] 45 1e-04 gi|23111026 sorting nexin 11 [Homo sapiens] 45 1e-04 gi|23111028 sorting nexin 11 [Homo sapiens] 45 1e-04 >gi|23397574 sorting nexin 33 [Homo sapiens] Length = 574 Score = 1174 bits (3036), Expect = 0.0 Identities = 574/574 (100%), Positives = 574/574 (100%) Query: 1 MALKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVR 60 MALKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVR Sbjct: 1 MALKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVR 60 Query: 61 SGISTNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSGFLSNQGSFEEDDDDDWDDW 120 SGISTNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSGFLSNQGSFEEDDDDDWDDW Sbjct: 61 SGISTNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSGFLSNQGSFEEDDDDDWDDW 120 Query: 121 DDGCTVVEEPRAGGLGTNGHPPLNLSYPGAYPSQHMAFRPKPPLERQDSLASAKRGSVVG 180 DDGCTVVEEPRAGGLGTNGHPPLNLSYPGAYPSQHMAFRPKPPLERQDSLASAKRGSVVG Sbjct: 121 DDGCTVVEEPRAGGLGTNGHPPLNLSYPGAYPSQHMAFRPKPPLERQDSLASAKRGSVVG 180 Query: 181 RNLNRFSCFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQ 240 RNLNRFSCFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQ Sbjct: 181 RNLNRFSCFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQ 240 Query: 241 TKFKGIKSYISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEE 300 TKFKGIKSYISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEE Sbjct: 241 TKFKGIKSYISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEE 300 Query: 301 DFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWKMGKRRAEKDEMVGASFLL 360 DFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWKMGKRRAEKDEMVGASFLL Sbjct: 301 DFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWKMGKRRAEKDEMVGASFLL 360 Query: 361 TFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSA 420 TFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSA Sbjct: 361 TFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSA 420 Query: 421 FQAISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLS 480 FQAISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLS Sbjct: 421 FQAISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLS 480 Query: 481 NFPDIIHLQKGAFAKVKESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRREL 540 NFPDIIHLQKGAFAKVKESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRREL Sbjct: 481 NFPDIIHLQKGAFAKVKESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRREL 540 Query: 541 DFKHMMQNYLRQQILFYQRVGQQLEKTLRMYDNL 574 DFKHMMQNYLRQQILFYQRVGQQLEKTLRMYDNL Sbjct: 541 DFKHMMQNYLRQQILFYQRVGQQLEKTLRMYDNL 574 >gi|157057545 sorting nexin 18 isoform a [Homo sapiens] Length = 624 Score = 587 bits (1514), Expect = e-168 Identities = 318/631 (50%), Positives = 412/631 (65%), Gaps = 64/631 (10%) Query: 1 MALKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVR 60 MAL+ RALYDF SEN EIS+++ E L + SE ++GWL+G NSRG+ GLFPASYV+++R Sbjct: 1 MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60 Query: 61 S--------GISTNHADYSSSPAGS---------------PGAQVSLYNS-----PSVAS 92 + G A Y++ P G P A +L PS Sbjct: 61 APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120 Query: 93 PARSG----GGS----------GFLSNQGSFEEDDDDDWDD-WDDGCTVVEEPRAGGLGT 137 P +G GG+ G+ ++QGS DDDWDD WDD TV +EP G LG+ Sbjct: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGS-----DDDWDDEWDDSSTVADEP--GALGS 173 Query: 138 NGHPPLNLSYP---GAYPSQHMAFRPKPPLER-------QDSLASAKRGSVVGRNLNRFS 187 +P L+ S GA ++ R L Q + K + V RNLNRFS Sbjct: 174 GAYPDLDGSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFS 233 Query: 188 CFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQTKFKGIK 247 FV+SG EAF+LG+ K + + +GP GP+W+ NP+PF C+++DPTKQTKFKG+K Sbjct: 234 TFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMK 293 Query: 248 SYISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRK 307 SYISYKL PTH PV+RRYKHFDWLY RL KF VISVPHLPEKQATGRFEEDFI KR+ Sbjct: 294 SYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRR 353 Query: 308 RRLILWMDHMTSHPVLSQYEGFQHFLSC---LDDKQWKMGKRRAEKDEMVGASFLLTFQI 364 + LI WM+HM SHPVL+Q + FQHFL+C D+K WK GKR+AEKDEMVGA+F LT Sbjct: 354 KGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLST 413 Query: 365 -PTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSAFQA 423 P DLQ+VE ++D FK F+KKMDDS LQL+ A+E RK V GF+KE+QK+G +F+ Sbjct: 414 PPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRG 473 Query: 424 ISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFP 483 +S +F++D S LN AI+ TG Y+AIGE+FAEQP+ DL ++D L+LYQG L+NFP Sbjct: 474 LSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFP 533 Query: 484 DIIHLQKGAFAKVKESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRRELDFK 543 DIIH+QKGA KVKES+R +EG+M +ADGI+ RC + FA AE++HFHQ R DFK Sbjct: 534 DIIHVQKGALTKVKESRRHVEEGKMEVQKADGIQDRCNTISFATLAEIHHFHQIRVRDFK 593 Query: 544 HMMQNYLRQQILFYQRVGQQLEKTLRMYDNL 574 MQ++L+QQI+F+Q+V Q+LE+ L YD++ Sbjct: 594 SQMQHFLQQQIIFFQKVTQKLEEALHKYDSV 624 >gi|224177511 sorting nexin 18 isoform c [Homo sapiens] Length = 591 Score = 499 bits (1286), Expect = e-141 Identities = 275/548 (50%), Positives = 351/548 (64%), Gaps = 64/548 (11%) Query: 1 MALKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVR 60 MAL+ RALYDF SEN EIS+++ E L + SE ++GWL+G NSRG+ GLFPASYV+++R Sbjct: 1 MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60 Query: 61 S--------GISTNHADYSSSPAGS---------------PGAQVSLYNS-----PSVAS 92 + G A Y++ P G P A +L PS Sbjct: 61 APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120 Query: 93 PARSG----GGS----------GFLSNQGSFEEDDDDDWDD-WDDGCTVVEEPRAGGLGT 137 P +G GG+ G+ ++QGS DDDWDD WDD TV +EP G LG+ Sbjct: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGS-----DDDWDDEWDDSSTVADEP--GALGS 173 Query: 138 NGHPPLNLSYP---GAYPSQHMAFRPKPPLER-------QDSLASAKRGSVVGRNLNRFS 187 +P L+ S GA ++ R L Q + K + V RNLNRFS Sbjct: 174 GAYPDLDGSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFS 233 Query: 188 CFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQTKFKGIK 247 FV+SG EAF+LG+ K + + +GP GP+W+ NP+PF C+++DPTKQTKFKG+K Sbjct: 234 TFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMK 293 Query: 248 SYISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRK 307 SYISYKL PTH PV+RRYKHFDWLY RL KF VISVPHLPEKQATGRFEEDFI KR+ Sbjct: 294 SYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRR 353 Query: 308 RRLILWMDHMTSHPVLSQYEGFQHFLSC---LDDKQWKMGKRRAEKDEMVGASFLLTFQI 364 + LI WM+HM SHPVL+Q + FQHFL+C D+K WK GKR+AEKDEMVGA+F LT Sbjct: 354 KGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLST 413 Query: 365 -PTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSAFQA 423 P DLQ+VE ++D FK F+KKMDDS LQL+ A+E RK V GF+KE+QK+G +F+ Sbjct: 414 PPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRG 473 Query: 424 ISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFP 483 +S +F++D S LN AI+ TG Y+AIGE+FAEQP+ DL ++D L+LYQG L+NFP Sbjct: 474 LSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFP 533 Query: 484 DIIHLQKG 491 DIIH+QKG Sbjct: 534 DIIHVQKG 541 >gi|157057543 sorting nexin 18 isoform b [Homo sapiens] Length = 628 Score = 499 bits (1286), Expect = e-141 Identities = 275/548 (50%), Positives = 351/548 (64%), Gaps = 64/548 (11%) Query: 1 MALKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVR 60 MAL+ RALYDF SEN EIS+++ E L + SE ++GWL+G NSRG+ GLFPASYV+++R Sbjct: 1 MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60 Query: 61 S--------GISTNHADYSSSPAGS---------------PGAQVSLYNS-----PSVAS 92 + G A Y++ P G P A +L PS Sbjct: 61 APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120 Query: 93 PARSG----GGS----------GFLSNQGSFEEDDDDDWDD-WDDGCTVVEEPRAGGLGT 137 P +G GG+ G+ ++QGS DDDWDD WDD TV +EP G LG+ Sbjct: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGS-----DDDWDDEWDDSSTVADEP--GALGS 173 Query: 138 NGHPPLNLSYP---GAYPSQHMAFRPKPPLER-------QDSLASAKRGSVVGRNLNRFS 187 +P L+ S GA ++ R L Q + K + V RNLNRFS Sbjct: 174 GAYPDLDGSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFS 233 Query: 188 CFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQTKFKGIK 247 FV+SG EAF+LG+ K + + +GP GP+W+ NP+PF C+++DPTKQTKFKG+K Sbjct: 234 TFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMK 293 Query: 248 SYISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRK 307 SYISYKL PTH PV+RRYKHFDWLY RL KF VISVPHLPEKQATGRFEEDFI KR+ Sbjct: 294 SYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRR 353 Query: 308 RRLILWMDHMTSHPVLSQYEGFQHFLSC---LDDKQWKMGKRRAEKDEMVGASFLLTFQI 364 + LI WM+HM SHPVL+Q + FQHFL+C D+K WK GKR+AEKDEMVGA+F LT Sbjct: 354 KGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLST 413 Query: 365 -PTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSAFQA 423 P DLQ+VE ++D FK F+KKMDDS LQL+ A+E RK V GF+KE+QK+G +F+ Sbjct: 414 PPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRG 473 Query: 424 ISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFP 483 +S +F++D S LN AI+ TG Y+AIGE+FAEQP+ DL ++D L+LYQG L+NFP Sbjct: 474 LSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFP 533 Query: 484 DIIHLQKG 491 DIIH+QKG Sbjct: 534 DIIHVQKG 541 >gi|7706706 sorting nexin 9 [Homo sapiens] Length = 595 Score = 355 bits (912), Expect = 5e-98 Identities = 213/601 (35%), Positives = 310/601 (51%), Gaps = 39/601 (6%) Query: 1 MALKGRALYDFHSE-NKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIV 59 MA K R +YDF +E E+++ + E + I + GWL+G+N +GE GL P YVEI+ Sbjct: 1 MATKARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEIL 60 Query: 60 RSGISTNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSGFLSNQGSFEEDDDDDWD- 118 S + G+ A + +S S AS A++ + ++Q D W Sbjct: 61 PSDGKDQFS------CGNSVADQAFLDSLS-ASTAQASSSAASNNHQVGSGNDPWSAWSA 113 Query: 119 ----DWDDGCTVVEEPRAGGLGTNGHPPLNLSYPGAYPSQHMAFR-------------PK 161 +W+ +P G N + P N +P + PK Sbjct: 114 SKSGNWESSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPK 173 Query: 162 PPLERQDSLASAKRGSVVGRN----------LNRFSCFVRSGVEAFILGDVPMMAKIAET 211 +DS ++ G+ G + LN+F F + G E ++L +AK E Sbjct: 174 SSSYFKDSESADAGGAQRGNSRASSSSMKIPLNKFPGFAKPGTEQYLLAK--QLAKPKEK 231 Query: 212 YSIEMGPRGPQWKANPHPFACSVEDPTKQTKFKGIKSYISYKLTPTHAASPVYRRYKHFD 271 I +G GP W F C V DP K +K G+KSYI Y+LTPT+ V RYKHFD Sbjct: 232 IPIIVGDYGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFD 291 Query: 272 WLYNRLLHKF-TVISVPHLPEKQATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQ 330 WLY RLL KF + I +P LP+KQ TGRFEE+FI+ R RL WM M HPV+S+ E FQ Sbjct: 292 WLYERLLVKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQ 351 Query: 331 HFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDD 390 FL+ D+K+WK GKR+AE+DE+ G T + DL ++E + + F+K MDD Sbjct: 352 QFLNFRDEKEWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDD 411 Query: 391 SVLQLSTVASELVRKHVGGFRKEFQKLGSAFQAISHSFQMDPPFCSEALNSAISHTGRTY 450 V +L TV E ++ G KE+QK+G A Q+++ F LN AI+ G+TY Sbjct: 412 GVKELLTVGQEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTY 471 Query: 451 EAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMVQ 510 E I + AEQPK DL +++ Y+G L FPDII KGA KVKES ++ ++ Sbjct: 472 EEIASLVAEQPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITL 531 Query: 511 DEADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQNYLRQQILFYQRVGQQLEKTLRM 570 + + +R ++ +ALQAEMNHFH R D+ +++ YL QQ+ FY+ + ++L + L Sbjct: 532 QDKQNMVKRVSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSR 591 Query: 571 Y 571 + Sbjct: 592 F 592 >gi|153791707 sorting nexin family member 30 [Homo sapiens] Length = 437 Score = 71.6 bits (174), Expect = 2e-12 Identities = 75/347 (21%), Positives = 145/347 (41%), Gaps = 44/347 (12%) Query: 234 VEDPTKQTKFKGIKSYISYKLTPTHAASP-------VYRRYKHFDWLYNRLLHKFTVISV 286 V+DP K +++YI+Y++T V RRY+ FDWL ++L + Sbjct: 95 VDDPKKHVCT--METYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHLI 152 Query: 287 PHLPEK----QATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWK 342 P LPEK RF E+F+E R++ L ++ +T HPVLS E F FL+ D +K Sbjct: 153 PPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFLTAKDLNAYK 212 Query: 343 -----MGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLST 397 + R E + V +++ T + + D +DTF L+L T Sbjct: 213 KQGIALLTRMGESVKHVTGG----YKLRTRPLEFAAIGDYLDTF----------ALKLGT 258 Query: 398 ---VASELVRKHVGGF--RKEFQKLGSAFQAISHSFQMDPPFCSEALNSAISHTGRTYEA 452 +A ++++ + +E+ + S + A+ +E L + G A Sbjct: 259 IDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGEL-------AEPLEGVSACIGNCSTA 311 Query: 453 IGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMVQDE 512 + E+ + ++ L + + + + S +Q AK++ ++ V + Sbjct: 312 LEELTDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAVALRKEDRPKVPAD 371 Query: 513 ADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQNYLRQQILFYQR 559 + + R L+A+M + + DF+ ++ + I +Y++ Sbjct: 372 VEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEK 418 >gi|23943858 sorting nexin 8 [Homo sapiens] Length = 465 Score = 64.3 bits (155), Expect = 3e-10 Identities = 63/257 (24%), Positives = 115/257 (44%), Gaps = 17/257 (6%) Query: 249 YISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRKR 308 ++ Y+++ S VYRRY F LLHKF VP LP K+ G + +FIE R+R Sbjct: 92 HVEYEVSSQRFKSSVYRRYNDFVVFQEMLLHKFPYRMVPALPPKRMLGA-DREFIEARRR 150 Query: 309 RLILWMDHMTSHPVLSQYEGFQHFLSCL-DDKQWKMGKRRAEKDEMVGASFLLTFQIPTE 367 L +++ + HP+ S+ + FLS D Q K+ E + VG F L ++ T Sbjct: 151 ALKRFVNLVARHPLFSEDVVLKLFLSFSGSDVQNKL----KESAQCVGDEF-LNCKLATR 205 Query: 368 HQDL--QDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGG------FRKEFQKLGS 419 +D D++ + + + + +S +L A + + + F KE +GS Sbjct: 206 AKDFLPADIQAQFAISRELIRNIYNSFHKLRDRAERIASRAIDNAADLLIFGKELSAIGS 265 Query: 420 AFQAISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLL 479 + ++ +L A+ + + + A+Q K + +++ L+L+ LL Sbjct: 266 DTTPLPSWAALNSSTWG-SLKQALKGLSVEFALLADKAAQQGKQEENDVVEKLNLFLDLL 324 Query: 480 SNFPDIIHL-QKGAFAK 495 ++ D+ +KG K Sbjct: 325 QSYKDLCERHEKGVLHK 341 >gi|23111036 sorting nexin 1 isoform c [Homo sapiens] Length = 474 Score = 57.0 bits (136), Expect = 5e-08 Identities = 104/493 (21%), Positives = 184/493 (37%), Gaps = 97/493 (19%) Query: 122 DGCTVVEEPRAGGLGTNGHPPLNLSYPGAYPSQHMAFRPKPPLERQDSLASAKRGSVVGR 181 +G EP AG T G ++ A S+H + + L ++ S + G + Sbjct: 26 EGAAGGSEPEAGDSDTEGE---DIFTGAAVVSKHQSPKITTSLLPINN-GSKENGIHEEQ 81 Query: 182 NLNRFSCFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQT 241 + F + VE + K+ I + P+ + P P +E+ ++ Sbjct: 82 DQEPQDLFADATVELSLDSTQNNQKKVLAKTLISLPPQEATNSSKPQPTYEELEEEEQED 141 Query: 242 KFK-------------GIKSYISYKLTPTHAASPVYR--------RYKHFDWLYNRLLHK 280 +F G+ +Y++YK+T T + P++R R+ F LY +L K Sbjct: 142 QFDLTVGITDPEKIGDGMNAYVAYKVT-TQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEK 200 Query: 281 FTV--ISVPHLPEKQATGRFE----------EDFIEKRKRRLILWMDHMTSHPVLSQYEG 328 + VP PEK G + +F+EKR+ L ++ + +HP + Q Sbjct: 201 HSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPD 260 Query: 329 FQHFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVE-DRVDTFKAFSKK 387 + FL + + R + GA L F T+ ++ + D + F +K Sbjct: 261 VREFL------EKEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIW--FEEK 312 Query: 388 M------DDSVLQLSTVASELVRK------HVGGFRKEFQKLGSAFQAISHSFQMDPPFC 435 + + + +L V LV + F K LGS+ Sbjct: 313 LQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSED------------- 359 Query: 436 SEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAK 495 + AL+ A+S E I ++ EQ ND F + + LS Y LL+ I+ Sbjct: 360 NTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLA----IVRW------- 408 Query: 496 VKESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQNYLRQQIL 555 E R+ Q E D R + ++ E+ F + + DFK+ + YL + Sbjct: 409 ---------ESRVTQYERDFER-----ISTVVRKEVIRFEKEKSKDFKNHVIKYLETLLY 454 Query: 556 FYQRVGQQLEKTL 568 Q++ + E L Sbjct: 455 SQQQLAKYWEAFL 467 >gi|19224660 protein kinase C and casein kinase substrate in neurons 3 [Homo sapiens] Length = 424 Score = 55.1 bits (131), Expect = 2e-07 Identities = 25/54 (46%), Positives = 34/54 (62%) Query: 6 RALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIV 59 RALYD+ + +E+S + E+L+ SE GW QGQ G GL+PA+YVE V Sbjct: 369 RALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPANYVECV 422 >gi|23111034 sorting nexin 1 isoform a [Homo sapiens] Length = 522 Score = 53.9 bits (128), Expect = 4e-07 Identities = 106/516 (20%), Positives = 190/516 (36%), Gaps = 95/516 (18%) Query: 122 DGCTVVEEPRAGGLGTNGHPPLNLSYPGAYPSQHMAFRPKPPLERQDSLASAKRGSVVGR 181 +G EP AG T G ++ A S+H + + L ++ S + G + Sbjct: 26 EGAAGGSEPEAGDSDTEGE---DIFTGAAVVSKHQSPKITTSLLPINN-GSKENGIHEEQ 81 Query: 182 NLNRFSCFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQT 241 + F + VE + K+ I + P+ + P P +E+ ++ Sbjct: 82 DQEPQDLFADATVELSLDSTQNNQKKVLAKTLISLPPQEATNSSKPQPTYEELEEEEQED 141 Query: 242 KFK-------------GIKSYISYKLTPTHAASPVYR--------RYKHFDWLYNRLLHK 280 +F G+ +Y++YK+T T + P++R R+ F LY +L K Sbjct: 142 QFDLTVGITDPEKIGDGMNAYVAYKVT-TQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEK 200 Query: 281 FTV--ISVPHLPEKQATGRFE----------EDFIEKRKRRLILWMDHMTSHPVLSQYEG 328 + VP PEK G + +F+EKR+ L ++ + +HP + Q Sbjct: 201 HSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPD 260 Query: 329 FQHFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVE-DRVDTFKAFSKK 387 + FL + + R + GA L F T+ ++ + D + F +K Sbjct: 261 VREFL------EKEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIW--FEEK 312 Query: 388 M------DDSVLQLSTVASELVRK------HVGGFRKEFQKLGSAFQAISHSFQMDPPFC 435 + + + +L V LV + F K LGS+ Sbjct: 313 LQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSED------------- 359 Query: 436 SEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLS--------------N 481 + AL+ A+S E I ++ EQ ND F + + LS Y LL+ Sbjct: 360 NTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQR 419 Query: 482 FPDI-IHLQKGAFAKVK--------ESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMN 532 + D LQK A+ + + Q+ DE + R + ++ E+ Sbjct: 420 WQDAQATLQKKREAEARLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVI 479 Query: 533 HFHQRRELDFKHMMQNYLRQQILFYQRVGQQLEKTL 568 F + + DFK+ + YL + Q++ + E L Sbjct: 480 RFEKEKSKDFKNHVIKYLETLLYSQQQLAKYWEAFL 515 >gi|23111055 sorting nexin 7 isoform b [Homo sapiens] Length = 336 Score = 53.9 bits (128), Expect = 4e-07 Identities = 36/128 (28%), Positives = 66/128 (51%), Gaps = 16/128 (12%) Query: 233 SVEDPTKQTKFKGIKSYISYKL-TPTHAAS------PVYRRYKHFDWLYNRLLHKFTVIS 285 +V++P ++ I+++I+Y++ T T V RRY+ F WL +L + Sbjct: 35 TVDEP--ESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLI 92 Query: 286 VPHLPEK----QATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQW 341 +P LPEK RF +DFIE R++ L +++ + HP L+ E F+ FL+ + W Sbjct: 93 IPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTA---QAW 149 Query: 342 KMGKRRAE 349 ++ + + Sbjct: 150 ELSSHKKQ 157 >gi|194294540 sorting nexin 7 isoform a [Homo sapiens] Length = 451 Score = 53.9 bits (128), Expect = 4e-07 Identities = 36/128 (28%), Positives = 66/128 (51%), Gaps = 16/128 (12%) Query: 233 SVEDPTKQTKFKGIKSYISYKL-TPTHAAS------PVYRRYKHFDWLYNRLLHKFTVIS 285 +V++P ++ I+++I+Y++ T T V RRY+ F WL +L + Sbjct: 99 TVDEP--ESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLI 156 Query: 286 VPHLPEK----QATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQW 341 +P LPEK RF +DFIE R++ L +++ + HP L+ E F+ FL+ + W Sbjct: 157 IPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTA---QAW 213 Query: 342 KMGKRRAE 349 ++ + + Sbjct: 214 ELSSHKKQ 221 >gi|23111038 sorting nexin 2 [Homo sapiens] Length = 519 Score = 53.5 bits (127), Expect = 5e-07 Identities = 81/381 (21%), Positives = 142/381 (37%), Gaps = 76/381 (19%) Query: 234 VEDPTKQTKFKGIKSYISYKLTPTHAAS-------PVYRRYKHFDWLYNRLLHKFTVIS- 285 V DP K G+ +Y++Y++T + S V RR+ F L+++L K+ + Sbjct: 146 VSDPEKVGD--GMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGY 203 Query: 286 -VPHLPEKQATGRFE----------EDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLS 334 VP PEK G + +F+EKR+ L ++ HP L Q + FL Sbjct: 204 IVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLE 263 Query: 335 CLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDDS--- 391 + R + GA L+ V D + KM++S Sbjct: 264 SSE------LPRAVNTQALSGAGI------------LRMVNKAADAVNKMTIKMNESDAW 305 Query: 392 ----VLQLSTVASELVRKHVG-----GFRKEFQKLGSAFQAISHSFQMDPPFCSEALNSA 442 Q + +L + HV RKE +AF + + AL+ A Sbjct: 306 FEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAF--AKSAAMLGNSEDHTALSRA 363 Query: 443 ISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQ-- 500 +S E I ++ EQ D + + LS Y L++ + + + K +++Q Sbjct: 364 LSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQIT 423 Query: 501 ----RMSDEGRMVQDEADGIR-----------------RRCRVVGFALQAEMNHFHQRRE 539 R ++ MV ++ D I+ R + ++ E+ F + R Sbjct: 424 LLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEKERV 483 Query: 540 LDFKHMMQNYLRQQILFYQRV 560 DFK ++ YL + Q++ Sbjct: 484 KDFKTVIIKYLESLVQTQQQL 504 >gi|23111032 sorting nexin 1 isoform b [Homo sapiens] Length = 457 Score = 52.8 bits (125), Expect = 9e-07 Identities = 83/380 (21%), Positives = 145/380 (38%), Gaps = 78/380 (20%) Query: 245 GIKSYISYKLTPTHAASPVYR--------RYKHFDWLYNRLLHKFTV--ISVPHLPEKQA 294 G+ +Y++YK+T T + P++R R+ F LY +L K + VP PEK Sbjct: 93 GMNAYVAYKVT-TQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSL 151 Query: 295 TGRFE----------EDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWKMG 344 G + +F+EKR+ L ++ + +HP + Q + FL + + Sbjct: 152 IGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFL------EKEEL 205 Query: 345 KRRAEKDEMVGASFLLTFQIPTEHQDLQDVE-DRVDTFKAFSKKM------DDSVLQLST 397 R + GA L F T+ ++ + D + F +K+ + + +L Sbjct: 206 PRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIW--FEEKLQEVECEEQRLRKLHA 263 Query: 398 VASELVRK------HVGGFRKEFQKLGSAFQAISHSFQMDPPFCSEALNSAISHTGRTYE 451 V LV + F K LGS+ + AL+ A+S E Sbjct: 264 VVETLVNHRKELALNTAQFAKSLAMLGSSED-------------NTALSRALSQLAEVEE 310 Query: 452 AIGEMFAEQPKNDLFQMLDTLSLYQGLLS--------------NFPDI-IHLQKGAFAKV 496 I ++ EQ ND F + + LS Y LL+ + D LQK A+ Sbjct: 311 KIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEA 370 Query: 497 K--------ESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQN 548 + + Q+ DE + R + ++ E+ F + + DFK+ + Sbjct: 371 RLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIK 430 Query: 549 YLRQQILFYQRVGQQLEKTL 568 YL + Q++ + E L Sbjct: 431 YLETLLYSQQQLAKYWEAFL 450 >gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] Length = 1363 Score = 50.4 bits (119), Expect = 4e-06 Identities = 25/58 (43%), Positives = 35/58 (60%) Query: 450 YEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGR 507 + +GE+ A QP +L ++D L L QG N PDIIH+ K A KV ES++ EG+ Sbjct: 1285 FNTVGELXANQPIQELDPVMDLLVLSQGHQVNIPDIIHIHKEALTKVMESRQHVAEGK 1342 >gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] Length = 1366 Score = 50.4 bits (119), Expect = 4e-06 Identities = 25/58 (43%), Positives = 35/58 (60%) Query: 450 YEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGR 507 + +GE+ A QP +L ++D L L QG N PDIIH+ K A KV ES++ EG+ Sbjct: 1288 FNTVGELXANQPIQELDPVMDLLVLSQGHQVNIPDIIHIHKEALTKVMESRQHVAEGK 1345 >gi|24308229 protein kinase C and casein kinase substrate in neurons 1 [Homo sapiens] Length = 444 Score = 50.4 bits (119), Expect = 4e-06 Identities = 20/54 (37%), Positives = 34/54 (62%) Query: 6 RALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIV 59 RALYD+ + ++E+S + ++L E GW +G+ G+ GL+PA+YVE + Sbjct: 391 RALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLDSGQLGLYPANYVEAI 444 >gi|148747351 protein kinase C and casein kinase substrate in neurons 2 [Homo sapiens] Length = 486 Score = 50.1 bits (118), Expect = 6e-06 Identities = 19/55 (34%), Positives = 34/55 (61%) Query: 6 RALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVR 60 RALYD+ + +E+S + ++L + GW +G+ G+ GL+PA+YVE ++ Sbjct: 432 RALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAIQ 486 >gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] Length = 1220 Score = 48.9 bits (115), Expect = 1e-05 Identities = 36/130 (27%), Positives = 61/130 (46%), Gaps = 17/130 (13%) Query: 6 RALYDFHSENKEEISIQQDEDLVI------FSETSLDGWLQGQNSRGETGLFPASYVEIV 59 RALY F S + +EI+IQ + +++ S+T GWL G+ +G+TG FPA+Y E + Sbjct: 746 RALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGE-LKGKTGWFPANYAEKI 804 Query: 60 RSGISTNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSGFLSNQGSF---------E 110 + +P +++L +P+ + S S +N F E Sbjct: 805 PENEVPAPVKPVTDSTSAPAPKLALRETPAPLA-VTSSEPSTTPNNWADFSSTWPTSTNE 863 Query: 111 EDDDDDWDDW 120 + + D+WD W Sbjct: 864 KPETDNWDAW 873 Score = 35.4 bits (80), Expect = 0.14 Identities = 14/51 (27%), Positives = 32/51 (62%), Gaps = 2/51 (3%) Query: 8 LYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEI 58 +YD+ ++N +E++ + + + + ++ D W N G+ GLFP++YV++ Sbjct: 1163 MYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVN--GQVGLFPSNYVKL 1211 Score = 35.0 bits (79), Expect = 0.19 Identities = 27/99 (27%), Positives = 50/99 (50%), Gaps = 10/99 (10%) Query: 3 LKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVRSG 62 L+ +ALY + ++ ++ +++ + + + D W G+ +G+ G FP SYV+++ Sbjct: 916 LQAQALYPWRAKKDNHLNFNKNDVITVLEQQ--DMWWFGE-VQGQKGWFPKSYVKLISGP 972 Query: 63 ISTNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSG 101 I + +S +GS + SL VASPA SG Sbjct: 973 IRKS----TSMDSGSSESPASL---KRVASPAAKPVVSG 1004 >gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] Length = 1721 Score = 48.9 bits (115), Expect = 1e-05 Identities = 36/130 (27%), Positives = 61/130 (46%), Gaps = 17/130 (13%) Query: 6 RALYDFHSENKEEISIQQDEDLVI------FSETSLDGWLQGQNSRGETGLFPASYVEIV 59 RALY F S + +EI+IQ + +++ S+T GWL G+ +G+TG FPA+Y E + Sbjct: 746 RALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGE-LKGKTGWFPANYAEKI 804 Query: 60 RSGISTNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSGFLSNQGSF---------E 110 + +P +++L +P+ + S S +N F E Sbjct: 805 PENEVPAPVKPVTDSTSAPAPKLALRETPAPLA-VTSSEPSTTPNNWADFSSTWPTSTNE 863 Query: 111 EDDDDDWDDW 120 + + D+WD W Sbjct: 864 KPETDNWDAW 873 Score = 35.4 bits (80), Expect = 0.14 Identities = 14/51 (27%), Positives = 32/51 (62%), Gaps = 2/51 (3%) Query: 8 LYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEI 58 +YD+ ++N +E++ + + + + ++ D W N G+ GLFP++YV++ Sbjct: 1163 MYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVN--GQVGLFPSNYVKL 1211 Score = 35.0 bits (79), Expect = 0.19 Identities = 27/99 (27%), Positives = 50/99 (50%), Gaps = 10/99 (10%) Query: 3 LKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVRSG 62 L+ +ALY + ++ ++ +++ + + + D W G+ +G+ G FP SYV+++ Sbjct: 916 LQAQALYPWRAKKDNHLNFNKNDVITVLEQQ--DMWWFGE-VQGQKGWFPKSYVKLISGP 972 Query: 63 ISTNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSG 101 I + +S +GS + SL VASPA SG Sbjct: 973 IRKS----TSMDSGSSESPASL---KRVASPAAKPVVSG 1004 >gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-like [Homo sapiens] Length = 303 Score = 48.5 bits (114), Expect = 2e-05 Identities = 30/96 (31%), Positives = 45/96 (46%), Gaps = 3/96 (3%) Query: 6 RALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVE-IVRSGIS 64 R LYDF + E++ ++ E LVI + + W +N G G+ P YVE +VRS Sbjct: 129 RTLYDFPGNDAEDLPFKKGEILVIIEKPE-EQWWSARNKDGRVGMIPVPYVEKLVRSSPH 187 Query: 65 TNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGS 100 H + +S+ G P Y P +P + GS Sbjct: 188 GKHGNRNSNSYGIP-EPAHAYAQPQTTTPLPAVSGS 222 >gi|5453710 LIM and SH3 protein 1 [Homo sapiens] Length = 261 Score = 46.6 bits (109), Expect = 6e-05 Identities = 22/55 (40%), Positives = 37/55 (67%), Gaps = 2/55 (3%) Query: 6 RALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSR-GETGLFPASYVEIV 59 RA+YD+ + +++E+S QD D ++ + DGW+ G R G+TG+ PA+YVE + Sbjct: 208 RAVYDYSAADEDEVSF-QDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 >gi|5453758 nebulette sarcomeric isoform [Homo sapiens] Length = 1014 Score = 46.2 bits (108), Expect = 8e-05 Identities = 21/55 (38%), Positives = 37/55 (67%), Gaps = 2/55 (3%) Query: 6 RALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSR-GETGLFPASYVEIV 59 RA+YD+ +++++E+S +D D ++ + DGW+ G R G TG+ PA+Y+E V Sbjct: 960 RAMYDYSAQDEDEVSF-RDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 1013 >gi|47087157 nebulette non-muscle isoform [Homo sapiens] Length = 270 Score = 46.2 bits (108), Expect = 8e-05 Identities = 21/55 (38%), Positives = 37/55 (67%), Gaps = 2/55 (3%) Query: 6 RALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSR-GETGLFPASYVEIV 59 RA+YD+ +++++E+S +D D ++ + DGW+ G R G TG+ PA+Y+E V Sbjct: 216 RAMYDYSAQDEDEVSF-RDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269 >gi|38524622 formin binding protein 1 [Homo sapiens] Length = 617 Score = 45.4 bits (106), Expect = 1e-04 Identities = 20/53 (37%), Positives = 30/53 (56%) Query: 6 RALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEI 58 +ALY F +N+ IS+ + E L + E DGW + + + E G P SYVE+ Sbjct: 556 KALYTFEGQNEGTISVVEGETLYVIEEDKGDGWTRIRRNEDEEGYVPTSYVEV 608 >gi|171906575 drebrin-like isoform c [Homo sapiens] Length = 439 Score = 45.4 bits (106), Expect = 1e-04 Identities = 23/57 (40%), Positives = 34/57 (59%), Gaps = 1/57 (1%) Query: 3 LKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIV 59 L RALYD+ + + EIS E+L+ E +GW +G G G+FPA+YVE++ Sbjct: 383 LCARALYDYQAADDTEISFDP-ENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELI 438 >gi|62198235 drebrin-like isoform b [Homo sapiens] Length = 430 Score = 45.4 bits (106), Expect = 1e-04 Identities = 23/57 (40%), Positives = 34/57 (59%), Gaps = 1/57 (1%) Query: 3 LKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIV 59 L RALYD+ + + EIS E+L+ E +GW +G G G+FPA+YVE++ Sbjct: 374 LCARALYDYQAADDTEISFDP-ENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELI 429 >gi|21361670 drebrin-like isoform a [Homo sapiens] Length = 431 Score = 45.4 bits (106), Expect = 1e-04 Identities = 23/57 (40%), Positives = 34/57 (59%), Gaps = 1/57 (1%) Query: 3 LKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIV 59 L RALYD+ + + EIS E+L+ E +GW +G G G+FPA+YVE++ Sbjct: 375 LCARALYDYQAADDTEISFDP-ENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELI 430 >gi|23111026 sorting nexin 11 [Homo sapiens] Length = 270 Score = 45.4 bits (106), Expect = 1e-04 Identities = 31/97 (31%), Positives = 47/97 (48%), Gaps = 8/97 (8%) Query: 234 VEDPTKQTKFKGIKSYISYKL-------TPTHAASPVYRRYKHFDWLYNRLLHKFTVISV 286 V+DP Q + SY+ YK+ T S V RRY+ F WL +L ++ V Sbjct: 21 VQDPRVQNEGSW-NSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRKQLQRNAGLVPV 79 Query: 287 PHLPEKQATGRFEEDFIEKRKRRLILWMDHMTSHPVL 323 P LP K ++FIEKR++ L +++ + VL Sbjct: 80 PELPGKSTFFGTSDEFIEKRRQGLQHFLEKVLQSVVL 116 >gi|23111028 sorting nexin 11 [Homo sapiens] Length = 270 Score = 45.4 bits (106), Expect = 1e-04 Identities = 31/97 (31%), Positives = 47/97 (48%), Gaps = 8/97 (8%) Query: 234 VEDPTKQTKFKGIKSYISYKL-------TPTHAASPVYRRYKHFDWLYNRLLHKFTVISV 286 V+DP Q + SY+ YK+ T S V RRY+ F WL +L ++ V Sbjct: 21 VQDPRVQNEGSW-NSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRKQLQRNAGLVPV 79 Query: 287 PHLPEKQATGRFEEDFIEKRKRRLILWMDHMTSHPVL 323 P LP K ++FIEKR++ L +++ + VL Sbjct: 80 PELPGKSTFFGTSDEFIEKRRQGLQHFLEKVLQSVVL 116 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.134 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,408,074 Number of Sequences: 37866 Number of extensions: 1149153 Number of successful extensions: 4493 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 82 Number of HSP's successfully gapped in prelim test: 160 Number of HSP's that attempted gapping in prelim test: 4157 Number of HSP's gapped (non-prelim): 394 length of query: 574 length of database: 18,247,518 effective HSP length: 108 effective length of query: 466 effective length of database: 14,157,990 effective search space: 6597623340 effective search space used: 6597623340 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.