Guide to the Human Genome
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Search of human proteins with 23397574

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23397574 sorting nexin 33 [Homo sapiens]
         (574 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23397574 sorting nexin 33 [Homo sapiens]                          1174   0.0  
gi|157057545 sorting nexin 18 isoform a [Homo sapiens]                587   e-168
gi|224177511 sorting nexin 18 isoform c [Homo sapiens]                499   e-141
gi|157057543 sorting nexin 18 isoform b [Homo sapiens]                499   e-141
gi|7706706 sorting nexin 9 [Homo sapiens]                             355   5e-98
gi|153791707 sorting nexin family member 30 [Homo sapiens]             72   2e-12
gi|23943858 sorting nexin 8 [Homo sapiens]                             64   3e-10
gi|23111036 sorting nexin 1 isoform c [Homo sapiens]                   57   5e-08
gi|19224660 protein kinase C and casein kinase substrate in neur...    55   2e-07
gi|23111034 sorting nexin 1 isoform a [Homo sapiens]                   54   4e-07
gi|23111055 sorting nexin 7 isoform b [Homo sapiens]                   54   4e-07
gi|194294540 sorting nexin 7 isoform a [Homo sapiens]                  54   4e-07
gi|23111038 sorting nexin 2 [Homo sapiens]                             54   5e-07
gi|23111032 sorting nexin 1 isoform b [Homo sapiens]                   53   9e-07
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]       50   4e-06
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]       50   4e-06
gi|24308229 protein kinase C and casein kinase substrate in neur...    50   4e-06
gi|148747351 protein kinase C and casein kinase substrate in neu...    50   6e-06
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]                49   1e-05
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]                49   1e-05
gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-lik...    49   2e-05
gi|5453710 LIM and SH3 protein 1 [Homo sapiens]                        47   6e-05
gi|5453758 nebulette sarcomeric isoform [Homo sapiens]                 46   8e-05
gi|47087157 nebulette non-muscle isoform [Homo sapiens]                46   8e-05
gi|38524622 formin binding protein 1 [Homo sapiens]                    45   1e-04
gi|171906575 drebrin-like isoform c [Homo sapiens]                     45   1e-04
gi|62198235 drebrin-like isoform b [Homo sapiens]                      45   1e-04
gi|21361670 drebrin-like isoform a [Homo sapiens]                      45   1e-04
gi|23111026 sorting nexin 11 [Homo sapiens]                            45   1e-04
gi|23111028 sorting nexin 11 [Homo sapiens]                            45   1e-04

>gi|23397574 sorting nexin 33 [Homo sapiens]
          Length = 574

 Score = 1174 bits (3036), Expect = 0.0
 Identities = 574/574 (100%), Positives = 574/574 (100%)

Query: 1   MALKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVR 60
           MALKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVR
Sbjct: 1   MALKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVR 60

Query: 61  SGISTNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSGFLSNQGSFEEDDDDDWDDW 120
           SGISTNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSGFLSNQGSFEEDDDDDWDDW
Sbjct: 61  SGISTNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSGFLSNQGSFEEDDDDDWDDW 120

Query: 121 DDGCTVVEEPRAGGLGTNGHPPLNLSYPGAYPSQHMAFRPKPPLERQDSLASAKRGSVVG 180
           DDGCTVVEEPRAGGLGTNGHPPLNLSYPGAYPSQHMAFRPKPPLERQDSLASAKRGSVVG
Sbjct: 121 DDGCTVVEEPRAGGLGTNGHPPLNLSYPGAYPSQHMAFRPKPPLERQDSLASAKRGSVVG 180

Query: 181 RNLNRFSCFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQ 240
           RNLNRFSCFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQ
Sbjct: 181 RNLNRFSCFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQ 240

Query: 241 TKFKGIKSYISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEE 300
           TKFKGIKSYISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEE
Sbjct: 241 TKFKGIKSYISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEE 300

Query: 301 DFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWKMGKRRAEKDEMVGASFLL 360
           DFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWKMGKRRAEKDEMVGASFLL
Sbjct: 301 DFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWKMGKRRAEKDEMVGASFLL 360

Query: 361 TFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSA 420
           TFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSA
Sbjct: 361 TFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSA 420

Query: 421 FQAISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLS 480
           FQAISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLS
Sbjct: 421 FQAISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLS 480

Query: 481 NFPDIIHLQKGAFAKVKESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRREL 540
           NFPDIIHLQKGAFAKVKESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRREL
Sbjct: 481 NFPDIIHLQKGAFAKVKESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRREL 540

Query: 541 DFKHMMQNYLRQQILFYQRVGQQLEKTLRMYDNL 574
           DFKHMMQNYLRQQILFYQRVGQQLEKTLRMYDNL
Sbjct: 541 DFKHMMQNYLRQQILFYQRVGQQLEKTLRMYDNL 574


>gi|157057545 sorting nexin 18 isoform a [Homo sapiens]
          Length = 624

 Score =  587 bits (1514), Expect = e-168
 Identities = 318/631 (50%), Positives = 412/631 (65%), Gaps = 64/631 (10%)

Query: 1   MALKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVR 60
           MAL+ RALYDF SEN  EIS+++ E L + SE  ++GWL+G NSRG+ GLFPASYV+++R
Sbjct: 1   MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60

Query: 61  S--------GISTNHADYSSSPAGS---------------PGAQVSLYNS-----PSVAS 92
           +        G     A Y++ P G                P A  +L        PS   
Sbjct: 61  APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120

Query: 93  PARSG----GGS----------GFLSNQGSFEEDDDDDWDD-WDDGCTVVEEPRAGGLGT 137
           P  +G    GG+          G+ ++QGS     DDDWDD WDD  TV +EP  G LG+
Sbjct: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGS-----DDDWDDEWDDSSTVADEP--GALGS 173

Query: 138 NGHPPLNLSYP---GAYPSQHMAFRPKPPLER-------QDSLASAKRGSVVGRNLNRFS 187
             +P L+ S     GA     ++ R    L         Q   +  K  + V RNLNRFS
Sbjct: 174 GAYPDLDGSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFS 233

Query: 188 CFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQTKFKGIK 247
            FV+SG EAF+LG+     K  +   + +GP GP+W+ NP+PF C+++DPTKQTKFKG+K
Sbjct: 234 TFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMK 293

Query: 248 SYISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRK 307
           SYISYKL PTH   PV+RRYKHFDWLY RL  KF VISVPHLPEKQATGRFEEDFI KR+
Sbjct: 294 SYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRR 353

Query: 308 RRLILWMDHMTSHPVLSQYEGFQHFLSC---LDDKQWKMGKRRAEKDEMVGASFLLTFQI 364
           + LI WM+HM SHPVL+Q + FQHFL+C    D+K WK GKR+AEKDEMVGA+F LT   
Sbjct: 354 KGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLST 413

Query: 365 -PTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSAFQA 423
            P    DLQ+VE ++D FK F+KKMDDS LQL+  A+E  RK V GF+KE+QK+G +F+ 
Sbjct: 414 PPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRG 473

Query: 424 ISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFP 483
           +S +F++D    S  LN AI+ TG  Y+AIGE+FAEQP+ DL  ++D L+LYQG L+NFP
Sbjct: 474 LSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFP 533

Query: 484 DIIHLQKGAFAKVKESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRRELDFK 543
           DIIH+QKGA  KVKES+R  +EG+M   +ADGI+ RC  + FA  AE++HFHQ R  DFK
Sbjct: 534 DIIHVQKGALTKVKESRRHVEEGKMEVQKADGIQDRCNTISFATLAEIHHFHQIRVRDFK 593

Query: 544 HMMQNYLRQQILFYQRVGQQLEKTLRMYDNL 574
             MQ++L+QQI+F+Q+V Q+LE+ L  YD++
Sbjct: 594 SQMQHFLQQQIIFFQKVTQKLEEALHKYDSV 624


>gi|224177511 sorting nexin 18 isoform c [Homo sapiens]
          Length = 591

 Score =  499 bits (1286), Expect = e-141
 Identities = 275/548 (50%), Positives = 351/548 (64%), Gaps = 64/548 (11%)

Query: 1   MALKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVR 60
           MAL+ RALYDF SEN  EIS+++ E L + SE  ++GWL+G NSRG+ GLFPASYV+++R
Sbjct: 1   MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60

Query: 61  S--------GISTNHADYSSSPAGS---------------PGAQVSLYNS-----PSVAS 92
           +        G     A Y++ P G                P A  +L        PS   
Sbjct: 61  APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120

Query: 93  PARSG----GGS----------GFLSNQGSFEEDDDDDWDD-WDDGCTVVEEPRAGGLGT 137
           P  +G    GG+          G+ ++QGS     DDDWDD WDD  TV +EP  G LG+
Sbjct: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGS-----DDDWDDEWDDSSTVADEP--GALGS 173

Query: 138 NGHPPLNLSYP---GAYPSQHMAFRPKPPLER-------QDSLASAKRGSVVGRNLNRFS 187
             +P L+ S     GA     ++ R    L         Q   +  K  + V RNLNRFS
Sbjct: 174 GAYPDLDGSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFS 233

Query: 188 CFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQTKFKGIK 247
            FV+SG EAF+LG+     K  +   + +GP GP+W+ NP+PF C+++DPTKQTKFKG+K
Sbjct: 234 TFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMK 293

Query: 248 SYISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRK 307
           SYISYKL PTH   PV+RRYKHFDWLY RL  KF VISVPHLPEKQATGRFEEDFI KR+
Sbjct: 294 SYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRR 353

Query: 308 RRLILWMDHMTSHPVLSQYEGFQHFLSC---LDDKQWKMGKRRAEKDEMVGASFLLTFQI 364
           + LI WM+HM SHPVL+Q + FQHFL+C    D+K WK GKR+AEKDEMVGA+F LT   
Sbjct: 354 KGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLST 413

Query: 365 -PTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSAFQA 423
            P    DLQ+VE ++D FK F+KKMDDS LQL+  A+E  RK V GF+KE+QK+G +F+ 
Sbjct: 414 PPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRG 473

Query: 424 ISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFP 483
           +S +F++D    S  LN AI+ TG  Y+AIGE+FAEQP+ DL  ++D L+LYQG L+NFP
Sbjct: 474 LSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFP 533

Query: 484 DIIHLQKG 491
           DIIH+QKG
Sbjct: 534 DIIHVQKG 541


>gi|157057543 sorting nexin 18 isoform b [Homo sapiens]
          Length = 628

 Score =  499 bits (1286), Expect = e-141
 Identities = 275/548 (50%), Positives = 351/548 (64%), Gaps = 64/548 (11%)

Query: 1   MALKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVR 60
           MAL+ RALYDF SEN  EIS+++ E L + SE  ++GWL+G NSRG+ GLFPASYV+++R
Sbjct: 1   MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60

Query: 61  S--------GISTNHADYSSSPAGS---------------PGAQVSLYNS-----PSVAS 92
           +        G     A Y++ P G                P A  +L        PS   
Sbjct: 61  APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120

Query: 93  PARSG----GGS----------GFLSNQGSFEEDDDDDWDD-WDDGCTVVEEPRAGGLGT 137
           P  +G    GG+          G+ ++QGS     DDDWDD WDD  TV +EP  G LG+
Sbjct: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGS-----DDDWDDEWDDSSTVADEP--GALGS 173

Query: 138 NGHPPLNLSYP---GAYPSQHMAFRPKPPLER-------QDSLASAKRGSVVGRNLNRFS 187
             +P L+ S     GA     ++ R    L         Q   +  K  + V RNLNRFS
Sbjct: 174 GAYPDLDGSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFS 233

Query: 188 CFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQTKFKGIK 247
            FV+SG EAF+LG+     K  +   + +GP GP+W+ NP+PF C+++DPTKQTKFKG+K
Sbjct: 234 TFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMK 293

Query: 248 SYISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRK 307
           SYISYKL PTH   PV+RRYKHFDWLY RL  KF VISVPHLPEKQATGRFEEDFI KR+
Sbjct: 294 SYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRR 353

Query: 308 RRLILWMDHMTSHPVLSQYEGFQHFLSC---LDDKQWKMGKRRAEKDEMVGASFLLTFQI 364
           + LI WM+HM SHPVL+Q + FQHFL+C    D+K WK GKR+AEKDEMVGA+F LT   
Sbjct: 354 KGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLST 413

Query: 365 -PTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSAFQA 423
            P    DLQ+VE ++D FK F+KKMDDS LQL+  A+E  RK V GF+KE+QK+G +F+ 
Sbjct: 414 PPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRG 473

Query: 424 ISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFP 483
           +S +F++D    S  LN AI+ TG  Y+AIGE+FAEQP+ DL  ++D L+LYQG L+NFP
Sbjct: 474 LSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFP 533

Query: 484 DIIHLQKG 491
           DIIH+QKG
Sbjct: 534 DIIHVQKG 541


>gi|7706706 sorting nexin 9 [Homo sapiens]
          Length = 595

 Score =  355 bits (912), Expect = 5e-98
 Identities = 213/601 (35%), Positives = 310/601 (51%), Gaps = 39/601 (6%)

Query: 1   MALKGRALYDFHSE-NKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIV 59
           MA K R +YDF +E    E+++ + E + I +     GWL+G+N +GE GL P  YVEI+
Sbjct: 1   MATKARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEIL 60

Query: 60  RSGISTNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSGFLSNQGSFEEDDDDDWD- 118
            S      +       G+  A  +  +S S AS A++   +   ++Q     D    W  
Sbjct: 61  PSDGKDQFS------CGNSVADQAFLDSLS-ASTAQASSSAASNNHQVGSGNDPWSAWSA 113

Query: 119 ----DWDDGCTVVEEPRAGGLGTNGHPPLNLSYPGAYPSQHMAFR-------------PK 161
               +W+       +P   G   N + P N      +P  +                 PK
Sbjct: 114 SKSGNWESSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQGPATGDDDDWDEDWDGPK 173

Query: 162 PPLERQDSLASAKRGSVVGRN----------LNRFSCFVRSGVEAFILGDVPMMAKIAET 211
                +DS ++   G+  G +          LN+F  F + G E ++L     +AK  E 
Sbjct: 174 SSSYFKDSESADAGGAQRGNSRASSSSMKIPLNKFPGFAKPGTEQYLLAK--QLAKPKEK 231

Query: 212 YSIEMGPRGPQWKANPHPFACSVEDPTKQTKFKGIKSYISYKLTPTHAASPVYRRYKHFD 271
             I +G  GP W      F C V DP K +K  G+KSYI Y+LTPT+    V  RYKHFD
Sbjct: 232 IPIIVGDYGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFD 291

Query: 272 WLYNRLLHKF-TVISVPHLPEKQATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQ 330
           WLY RLL KF + I +P LP+KQ TGRFEE+FI+ R  RL  WM  M  HPV+S+ E FQ
Sbjct: 292 WLYERLLVKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQ 351

Query: 331 HFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDD 390
            FL+  D+K+WK GKR+AE+DE+ G     T +      DL ++E + +    F+K MDD
Sbjct: 352 QFLNFRDEKEWKTGKRKAERDELAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDD 411

Query: 391 SVLQLSTVASELVRKHVGGFRKEFQKLGSAFQAISHSFQMDPPFCSEALNSAISHTGRTY 450
            V +L TV  E  ++  G   KE+QK+G A Q+++  F          LN AI+  G+TY
Sbjct: 412 GVKELLTVGQEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTY 471

Query: 451 EAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMVQ 510
           E I  + AEQPK DL  +++    Y+G L  FPDII   KGA  KVKES ++    ++  
Sbjct: 472 EEIASLVAEQPKKDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITL 531

Query: 511 DEADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQNYLRQQILFYQRVGQQLEKTLRM 570
            +   + +R  ++ +ALQAEMNHFH  R  D+  +++ YL QQ+ FY+ + ++L + L  
Sbjct: 532 QDKQNMVKRVSIMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSR 591

Query: 571 Y 571
           +
Sbjct: 592 F 592


>gi|153791707 sorting nexin family member 30 [Homo sapiens]
          Length = 437

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 75/347 (21%), Positives = 145/347 (41%), Gaps = 44/347 (12%)

Query: 234 VEDPTKQTKFKGIKSYISYKLTPTHAASP-------VYRRYKHFDWLYNRLLHKFTVISV 286
           V+DP K      +++YI+Y++T              V RRY+ FDWL ++L        +
Sbjct: 95  VDDPKKHVCT--METYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHLI 152

Query: 287 PHLPEK----QATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWK 342
           P LPEK        RF E+F+E R++ L  ++  +T HPVLS  E F  FL+  D   +K
Sbjct: 153 PPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFLTAKDLNAYK 212

Query: 343 -----MGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLST 397
                +  R  E  + V       +++ T   +   + D +DTF           L+L T
Sbjct: 213 KQGIALLTRMGESVKHVTGG----YKLRTRPLEFAAIGDYLDTF----------ALKLGT 258

Query: 398 ---VASELVRKHVGGF--RKEFQKLGSAFQAISHSFQMDPPFCSEALNSAISHTGRTYEA 452
              +A  ++++ +      +E+  + S + A+           +E L    +  G    A
Sbjct: 259 IDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGEL-------AEPLEGVSACIGNCSTA 311

Query: 453 IGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMVQDE 512
           + E+  +  ++ L  + + +     + S       +Q    AK++      ++   V  +
Sbjct: 312 LEELTDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAVALRKEDRPKVPAD 371

Query: 513 ADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQNYLRQQILFYQR 559
            +  + R       L+A+M  +   +  DF+ ++     + I +Y++
Sbjct: 372 VEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEK 418


>gi|23943858 sorting nexin 8 [Homo sapiens]
          Length = 465

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 63/257 (24%), Positives = 115/257 (44%), Gaps = 17/257 (6%)

Query: 249 YISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRKR 308
           ++ Y+++     S VYRRY  F      LLHKF    VP LP K+  G  + +FIE R+R
Sbjct: 92  HVEYEVSSQRFKSSVYRRYNDFVVFQEMLLHKFPYRMVPALPPKRMLGA-DREFIEARRR 150

Query: 309 RLILWMDHMTSHPVLSQYEGFQHFLSCL-DDKQWKMGKRRAEKDEMVGASFLLTFQIPTE 367
            L  +++ +  HP+ S+    + FLS    D Q K+     E  + VG  F L  ++ T 
Sbjct: 151 ALKRFVNLVARHPLFSEDVVLKLFLSFSGSDVQNKL----KESAQCVGDEF-LNCKLATR 205

Query: 368 HQDL--QDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGG------FRKEFQKLGS 419
            +D    D++ +    +   + + +S  +L   A  +  + +        F KE   +GS
Sbjct: 206 AKDFLPADIQAQFAISRELIRNIYNSFHKLRDRAERIASRAIDNAADLLIFGKELSAIGS 265

Query: 420 AFQAISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLL 479
               +     ++      +L  A+      +  + +  A+Q K +   +++ L+L+  LL
Sbjct: 266 DTTPLPSWAALNSSTWG-SLKQALKGLSVEFALLADKAAQQGKQEENDVVEKLNLFLDLL 324

Query: 480 SNFPDIIHL-QKGAFAK 495
            ++ D+    +KG   K
Sbjct: 325 QSYKDLCERHEKGVLHK 341


>gi|23111036 sorting nexin 1 isoform c [Homo sapiens]
          Length = 474

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 104/493 (21%), Positives = 184/493 (37%), Gaps = 97/493 (19%)

Query: 122 DGCTVVEEPRAGGLGTNGHPPLNLSYPGAYPSQHMAFRPKPPLERQDSLASAKRGSVVGR 181
           +G     EP AG   T G    ++    A  S+H + +    L   ++  S + G    +
Sbjct: 26  EGAAGGSEPEAGDSDTEGE---DIFTGAAVVSKHQSPKITTSLLPINN-GSKENGIHEEQ 81

Query: 182 NLNRFSCFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQT 241
           +      F  + VE  +        K+     I + P+     + P P    +E+  ++ 
Sbjct: 82  DQEPQDLFADATVELSLDSTQNNQKKVLAKTLISLPPQEATNSSKPQPTYEELEEEEQED 141

Query: 242 KFK-------------GIKSYISYKLTPTHAASPVYR--------RYKHFDWLYNRLLHK 280
           +F              G+ +Y++YK+T T  + P++R        R+  F  LY +L  K
Sbjct: 142 QFDLTVGITDPEKIGDGMNAYVAYKVT-TQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEK 200

Query: 281 FTV--ISVPHLPEKQATGRFE----------EDFIEKRKRRLILWMDHMTSHPVLSQYEG 328
            +     VP  PEK   G  +           +F+EKR+  L  ++  + +HP + Q   
Sbjct: 201 HSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPD 260

Query: 329 FQHFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVE-DRVDTFKAFSKK 387
            + FL      + +   R      + GA  L  F   T+      ++ +  D +  F +K
Sbjct: 261 VREFL------EKEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIW--FEEK 312

Query: 388 M------DDSVLQLSTVASELVRK------HVGGFRKEFQKLGSAFQAISHSFQMDPPFC 435
           +      +  + +L  V   LV        +   F K    LGS+               
Sbjct: 313 LQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSED------------- 359

Query: 436 SEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAK 495
           + AL+ A+S      E I ++  EQ  ND F + + LS Y  LL+    I+         
Sbjct: 360 NTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLA----IVRW------- 408

Query: 496 VKESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQNYLRQQIL 555
                    E R+ Q E D  R     +   ++ E+  F + +  DFK+ +  YL   + 
Sbjct: 409 ---------ESRVTQYERDFER-----ISTVVRKEVIRFEKEKSKDFKNHVIKYLETLLY 454

Query: 556 FYQRVGQQLEKTL 568
             Q++ +  E  L
Sbjct: 455 SQQQLAKYWEAFL 467


>gi|19224660 protein kinase C and casein kinase substrate in neurons
           3 [Homo sapiens]
          Length = 424

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 25/54 (46%), Positives = 34/54 (62%)

Query: 6   RALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIV 59
           RALYD+  +  +E+S +  E+L+  SE    GW QGQ   G  GL+PA+YVE V
Sbjct: 369 RALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPANYVECV 422


>gi|23111034 sorting nexin 1 isoform a [Homo sapiens]
          Length = 522

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 106/516 (20%), Positives = 190/516 (36%), Gaps = 95/516 (18%)

Query: 122 DGCTVVEEPRAGGLGTNGHPPLNLSYPGAYPSQHMAFRPKPPLERQDSLASAKRGSVVGR 181
           +G     EP AG   T G    ++    A  S+H + +    L   ++  S + G    +
Sbjct: 26  EGAAGGSEPEAGDSDTEGE---DIFTGAAVVSKHQSPKITTSLLPINN-GSKENGIHEEQ 81

Query: 182 NLNRFSCFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQT 241
           +      F  + VE  +        K+     I + P+     + P P    +E+  ++ 
Sbjct: 82  DQEPQDLFADATVELSLDSTQNNQKKVLAKTLISLPPQEATNSSKPQPTYEELEEEEQED 141

Query: 242 KFK-------------GIKSYISYKLTPTHAASPVYR--------RYKHFDWLYNRLLHK 280
           +F              G+ +Y++YK+T T  + P++R        R+  F  LY +L  K
Sbjct: 142 QFDLTVGITDPEKIGDGMNAYVAYKVT-TQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEK 200

Query: 281 FTV--ISVPHLPEKQATGRFE----------EDFIEKRKRRLILWMDHMTSHPVLSQYEG 328
            +     VP  PEK   G  +           +F+EKR+  L  ++  + +HP + Q   
Sbjct: 201 HSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPD 260

Query: 329 FQHFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVE-DRVDTFKAFSKK 387
            + FL      + +   R      + GA  L  F   T+      ++ +  D +  F +K
Sbjct: 261 VREFL------EKEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIW--FEEK 312

Query: 388 M------DDSVLQLSTVASELVRK------HVGGFRKEFQKLGSAFQAISHSFQMDPPFC 435
           +      +  + +L  V   LV        +   F K    LGS+               
Sbjct: 313 LQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSED------------- 359

Query: 436 SEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLS--------------N 481
           + AL+ A+S      E I ++  EQ  ND F + + LS Y  LL+               
Sbjct: 360 NTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQR 419

Query: 482 FPDI-IHLQKGAFAKVK--------ESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMN 532
           + D    LQK   A+ +        + Q+  DE    +       R    +   ++ E+ 
Sbjct: 420 WQDAQATLQKKREAEARLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVI 479

Query: 533 HFHQRRELDFKHMMQNYLRQQILFYQRVGQQLEKTL 568
            F + +  DFK+ +  YL   +   Q++ +  E  L
Sbjct: 480 RFEKEKSKDFKNHVIKYLETLLYSQQQLAKYWEAFL 515


>gi|23111055 sorting nexin 7 isoform b [Homo sapiens]
          Length = 336

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 36/128 (28%), Positives = 66/128 (51%), Gaps = 16/128 (12%)

Query: 233 SVEDPTKQTKFKGIKSYISYKL-TPTHAAS------PVYRRYKHFDWLYNRLLHKFTVIS 285
           +V++P  ++    I+++I+Y++ T T           V RRY+ F WL  +L      + 
Sbjct: 35  TVDEP--ESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLI 92

Query: 286 VPHLPEK----QATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQW 341
           +P LPEK        RF +DFIE R++ L  +++ +  HP L+  E F+ FL+    + W
Sbjct: 93  IPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTA---QAW 149

Query: 342 KMGKRRAE 349
           ++   + +
Sbjct: 150 ELSSHKKQ 157


>gi|194294540 sorting nexin 7 isoform a [Homo sapiens]
          Length = 451

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 36/128 (28%), Positives = 66/128 (51%), Gaps = 16/128 (12%)

Query: 233 SVEDPTKQTKFKGIKSYISYKL-TPTHAAS------PVYRRYKHFDWLYNRLLHKFTVIS 285
           +V++P  ++    I+++I+Y++ T T           V RRY+ F WL  +L      + 
Sbjct: 99  TVDEP--ESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLI 156

Query: 286 VPHLPEK----QATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQW 341
           +P LPEK        RF +DFIE R++ L  +++ +  HP L+  E F+ FL+    + W
Sbjct: 157 IPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTA---QAW 213

Query: 342 KMGKRRAE 349
           ++   + +
Sbjct: 214 ELSSHKKQ 221


>gi|23111038 sorting nexin 2 [Homo sapiens]
          Length = 519

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 81/381 (21%), Positives = 142/381 (37%), Gaps = 76/381 (19%)

Query: 234 VEDPTKQTKFKGIKSYISYKLTPTHAAS-------PVYRRYKHFDWLYNRLLHKFTVIS- 285
           V DP K     G+ +Y++Y++T   + S        V RR+  F  L+++L  K+  +  
Sbjct: 146 VSDPEKVGD--GMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGY 203

Query: 286 -VPHLPEKQATGRFE----------EDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLS 334
            VP  PEK   G  +           +F+EKR+  L  ++     HP L Q    + FL 
Sbjct: 204 IVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLE 263

Query: 335 CLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDDS--- 391
             +        R      + GA              L+ V    D     + KM++S   
Sbjct: 264 SSE------LPRAVNTQALSGAGI------------LRMVNKAADAVNKMTIKMNESDAW 305

Query: 392 ----VLQLSTVASELVRKHVG-----GFRKEFQKLGSAFQAISHSFQMDPPFCSEALNSA 442
                 Q   +  +L + HV        RKE     +AF     +  +       AL+ A
Sbjct: 306 FEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAF--AKSAAMLGNSEDHTALSRA 363

Query: 443 ISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQ-- 500
           +S      E I ++  EQ   D +   + LS Y  L++    +   +   + K +++Q  
Sbjct: 364 LSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQIT 423

Query: 501 ----RMSDEGRMVQDEADGIR-----------------RRCRVVGFALQAEMNHFHQRRE 539
               R ++   MV ++ D I+                 R    +   ++ E+  F + R 
Sbjct: 424 LLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEKERV 483

Query: 540 LDFKHMMQNYLRQQILFYQRV 560
            DFK ++  YL   +   Q++
Sbjct: 484 KDFKTVIIKYLESLVQTQQQL 504


>gi|23111032 sorting nexin 1 isoform b [Homo sapiens]
          Length = 457

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 83/380 (21%), Positives = 145/380 (38%), Gaps = 78/380 (20%)

Query: 245 GIKSYISYKLTPTHAASPVYR--------RYKHFDWLYNRLLHKFTV--ISVPHLPEKQA 294
           G+ +Y++YK+T T  + P++R        R+  F  LY +L  K +     VP  PEK  
Sbjct: 93  GMNAYVAYKVT-TQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSL 151

Query: 295 TGRFE----------EDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWKMG 344
            G  +           +F+EKR+  L  ++  + +HP + Q    + FL      + +  
Sbjct: 152 IGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFL------EKEEL 205

Query: 345 KRRAEKDEMVGASFLLTFQIPTEHQDLQDVE-DRVDTFKAFSKKM------DDSVLQLST 397
            R      + GA  L  F   T+      ++ +  D +  F +K+      +  + +L  
Sbjct: 206 PRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIW--FEEKLQEVECEEQRLRKLHA 263

Query: 398 VASELVRK------HVGGFRKEFQKLGSAFQAISHSFQMDPPFCSEALNSAISHTGRTYE 451
           V   LV        +   F K    LGS+               + AL+ A+S      E
Sbjct: 264 VVETLVNHRKELALNTAQFAKSLAMLGSSED-------------NTALSRALSQLAEVEE 310

Query: 452 AIGEMFAEQPKNDLFQMLDTLSLYQGLLS--------------NFPDI-IHLQKGAFAKV 496
            I ++  EQ  ND F + + LS Y  LL+               + D    LQK   A+ 
Sbjct: 311 KIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEA 370

Query: 497 K--------ESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQN 548
           +        + Q+  DE    +       R    +   ++ E+  F + +  DFK+ +  
Sbjct: 371 RLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIK 430

Query: 549 YLRQQILFYQRVGQQLEKTL 568
           YL   +   Q++ +  E  L
Sbjct: 431 YLETLLYSQQQLAKYWEAFL 450


>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1363

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 25/58 (43%), Positives = 35/58 (60%)

Query: 450  YEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGR 507
            +  +GE+ A QP  +L  ++D L L QG   N PDIIH+ K A  KV ES++   EG+
Sbjct: 1285 FNTVGELXANQPIQELDPVMDLLVLSQGHQVNIPDIIHIHKEALTKVMESRQHVAEGK 1342


>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1366

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 25/58 (43%), Positives = 35/58 (60%)

Query: 450  YEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGR 507
            +  +GE+ A QP  +L  ++D L L QG   N PDIIH+ K A  KV ES++   EG+
Sbjct: 1288 FNTVGELXANQPIQELDPVMDLLVLSQGHQVNIPDIIHIHKEALTKVMESRQHVAEGK 1345


>gi|24308229 protein kinase C and casein kinase substrate in neurons
           1 [Homo sapiens]
          Length = 444

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 20/54 (37%), Positives = 34/54 (62%)

Query: 6   RALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIV 59
           RALYD+  + ++E+S +  ++L    E    GW +G+   G+ GL+PA+YVE +
Sbjct: 391 RALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLDSGQLGLYPANYVEAI 444


>gi|148747351 protein kinase C and casein kinase substrate in
           neurons 2 [Homo sapiens]
          Length = 486

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 19/55 (34%), Positives = 34/55 (61%)

Query: 6   RALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVR 60
           RALYD+  +  +E+S +  ++L    +    GW +G+   G+ GL+PA+YVE ++
Sbjct: 432 RALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAIQ 486


>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
          Length = 1220

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 36/130 (27%), Positives = 61/130 (46%), Gaps = 17/130 (13%)

Query: 6   RALYDFHSENKEEISIQQDEDLVI------FSETSLDGWLQGQNSRGETGLFPASYVEIV 59
           RALY F S + +EI+IQ  + +++       S+T   GWL G+  +G+TG FPA+Y E +
Sbjct: 746 RALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGE-LKGKTGWFPANYAEKI 804

Query: 60  RSGISTNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSGFLSNQGSF---------E 110
                       +    +P  +++L  +P+  +   S   S   +N   F         E
Sbjct: 805 PENEVPAPVKPVTDSTSAPAPKLALRETPAPLA-VTSSEPSTTPNNWADFSSTWPTSTNE 863

Query: 111 EDDDDDWDDW 120
           + + D+WD W
Sbjct: 864 KPETDNWDAW 873



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 14/51 (27%), Positives = 32/51 (62%), Gaps = 2/51 (3%)

Query: 8    LYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEI 58
            +YD+ ++N +E++  + + + + ++   D W    N  G+ GLFP++YV++
Sbjct: 1163 MYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVN--GQVGLFPSNYVKL 1211



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 27/99 (27%), Positives = 50/99 (50%), Gaps = 10/99 (10%)

Query: 3    LKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVRSG 62
            L+ +ALY + ++    ++  +++ + +  +   D W  G+  +G+ G FP SYV+++   
Sbjct: 916  LQAQALYPWRAKKDNHLNFNKNDVITVLEQQ--DMWWFGE-VQGQKGWFPKSYVKLISGP 972

Query: 63   ISTNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSG 101
            I  +    +S  +GS  +  SL     VASPA     SG
Sbjct: 973  IRKS----TSMDSGSSESPASL---KRVASPAAKPVVSG 1004


>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
          Length = 1721

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 36/130 (27%), Positives = 61/130 (46%), Gaps = 17/130 (13%)

Query: 6   RALYDFHSENKEEISIQQDEDLVI------FSETSLDGWLQGQNSRGETGLFPASYVEIV 59
           RALY F S + +EI+IQ  + +++       S+T   GWL G+  +G+TG FPA+Y E +
Sbjct: 746 RALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGE-LKGKTGWFPANYAEKI 804

Query: 60  RSGISTNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSGFLSNQGSF---------E 110
                       +    +P  +++L  +P+  +   S   S   +N   F         E
Sbjct: 805 PENEVPAPVKPVTDSTSAPAPKLALRETPAPLA-VTSSEPSTTPNNWADFSSTWPTSTNE 863

Query: 111 EDDDDDWDDW 120
           + + D+WD W
Sbjct: 864 KPETDNWDAW 873



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 14/51 (27%), Positives = 32/51 (62%), Gaps = 2/51 (3%)

Query: 8    LYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEI 58
            +YD+ ++N +E++  + + + + ++   D W    N  G+ GLFP++YV++
Sbjct: 1163 MYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVN--GQVGLFPSNYVKL 1211



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 27/99 (27%), Positives = 50/99 (50%), Gaps = 10/99 (10%)

Query: 3    LKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVRSG 62
            L+ +ALY + ++    ++  +++ + +  +   D W  G+  +G+ G FP SYV+++   
Sbjct: 916  LQAQALYPWRAKKDNHLNFNKNDVITVLEQQ--DMWWFGE-VQGQKGWFPKSYVKLISGP 972

Query: 63   ISTNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSG 101
            I  +    +S  +GS  +  SL     VASPA     SG
Sbjct: 973  IRKS----TSMDSGSSESPASL---KRVASPAAKPVVSG 1004


>gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-like
           [Homo sapiens]
          Length = 303

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 30/96 (31%), Positives = 45/96 (46%), Gaps = 3/96 (3%)

Query: 6   RALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVE-IVRSGIS 64
           R LYDF   + E++  ++ E LVI  +   + W   +N  G  G+ P  YVE +VRS   
Sbjct: 129 RTLYDFPGNDAEDLPFKKGEILVIIEKPE-EQWWSARNKDGRVGMIPVPYVEKLVRSSPH 187

Query: 65  TNHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGS 100
             H + +S+  G P      Y  P   +P  +  GS
Sbjct: 188 GKHGNRNSNSYGIP-EPAHAYAQPQTTTPLPAVSGS 222


>gi|5453710 LIM and SH3 protein 1 [Homo sapiens]
          Length = 261

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 22/55 (40%), Positives = 37/55 (67%), Gaps = 2/55 (3%)

Query: 6   RALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSR-GETGLFPASYVEIV 59
           RA+YD+ + +++E+S  QD D ++  +   DGW+ G   R G+TG+ PA+YVE +
Sbjct: 208 RAVYDYSAADEDEVSF-QDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261


>gi|5453758 nebulette sarcomeric isoform [Homo sapiens]
          Length = 1014

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 21/55 (38%), Positives = 37/55 (67%), Gaps = 2/55 (3%)

Query: 6    RALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSR-GETGLFPASYVEIV 59
            RA+YD+ +++++E+S  +D D ++  +   DGW+ G   R G TG+ PA+Y+E V
Sbjct: 960  RAMYDYSAQDEDEVSF-RDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 1013


>gi|47087157 nebulette non-muscle isoform [Homo sapiens]
          Length = 270

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 21/55 (38%), Positives = 37/55 (67%), Gaps = 2/55 (3%)

Query: 6   RALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSR-GETGLFPASYVEIV 59
           RA+YD+ +++++E+S  +D D ++  +   DGW+ G   R G TG+ PA+Y+E V
Sbjct: 216 RAMYDYSAQDEDEVSF-RDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269


>gi|38524622 formin binding protein 1 [Homo sapiens]
          Length = 617

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 20/53 (37%), Positives = 30/53 (56%)

Query: 6   RALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEI 58
           +ALY F  +N+  IS+ + E L +  E   DGW + + +  E G  P SYVE+
Sbjct: 556 KALYTFEGQNEGTISVVEGETLYVIEEDKGDGWTRIRRNEDEEGYVPTSYVEV 608


>gi|171906575 drebrin-like isoform c [Homo sapiens]
          Length = 439

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 23/57 (40%), Positives = 34/57 (59%), Gaps = 1/57 (1%)

Query: 3   LKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIV 59
           L  RALYD+ + +  EIS    E+L+   E   +GW +G    G  G+FPA+YVE++
Sbjct: 383 LCARALYDYQAADDTEISFDP-ENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELI 438


>gi|62198235 drebrin-like isoform b [Homo sapiens]
          Length = 430

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 23/57 (40%), Positives = 34/57 (59%), Gaps = 1/57 (1%)

Query: 3   LKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIV 59
           L  RALYD+ + +  EIS    E+L+   E   +GW +G    G  G+FPA+YVE++
Sbjct: 374 LCARALYDYQAADDTEISFDP-ENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELI 429


>gi|21361670 drebrin-like isoform a [Homo sapiens]
          Length = 431

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 23/57 (40%), Positives = 34/57 (59%), Gaps = 1/57 (1%)

Query: 3   LKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIV 59
           L  RALYD+ + +  EIS    E+L+   E   +GW +G    G  G+FPA+YVE++
Sbjct: 375 LCARALYDYQAADDTEISFDP-ENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELI 430


>gi|23111026 sorting nexin 11 [Homo sapiens]
          Length = 270

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 31/97 (31%), Positives = 47/97 (48%), Gaps = 8/97 (8%)

Query: 234 VEDPTKQTKFKGIKSYISYKL-------TPTHAASPVYRRYKHFDWLYNRLLHKFTVISV 286
           V+DP  Q +     SY+ YK+         T   S V RRY+ F WL  +L     ++ V
Sbjct: 21  VQDPRVQNEGSW-NSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRKQLQRNAGLVPV 79

Query: 287 PHLPEKQATGRFEEDFIEKRKRRLILWMDHMTSHPVL 323
           P LP K       ++FIEKR++ L  +++ +    VL
Sbjct: 80  PELPGKSTFFGTSDEFIEKRRQGLQHFLEKVLQSVVL 116


>gi|23111028 sorting nexin 11 [Homo sapiens]
          Length = 270

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 31/97 (31%), Positives = 47/97 (48%), Gaps = 8/97 (8%)

Query: 234 VEDPTKQTKFKGIKSYISYKL-------TPTHAASPVYRRYKHFDWLYNRLLHKFTVISV 286
           V+DP  Q +     SY+ YK+         T   S V RRY+ F WL  +L     ++ V
Sbjct: 21  VQDPRVQNEGSW-NSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRKQLQRNAGLVPV 79

Query: 287 PHLPEKQATGRFEEDFIEKRKRRLILWMDHMTSHPVL 323
           P LP K       ++FIEKR++ L  +++ +    VL
Sbjct: 80  PELPGKSTFFGTSDEFIEKRRQGLQHFLEKVLQSVVL 116


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,408,074
Number of Sequences: 37866
Number of extensions: 1149153
Number of successful extensions: 4493
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 82
Number of HSP's successfully gapped in prelim test: 160
Number of HSP's that attempted gapping in prelim test: 4157
Number of HSP's gapped (non-prelim): 394
length of query: 574
length of database: 18,247,518
effective HSP length: 108
effective length of query: 466
effective length of database: 14,157,990
effective search space: 6597623340
effective search space used: 6597623340
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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