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Search of human proteins with 23312380
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23312380 protein phosphatase with EF hand calcium-binding
domain 1 isoform 1 [Homo sapiens]
(653 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23312380 protein phosphatase with EF hand calcium-binding dom... 1340 0.0
gi|23312374 protein phosphatase with EF hand calcium-binding dom... 1265 0.0
gi|23312378 protein phosphatase with EF hand calcium-binding dom... 735 0.0
gi|23312386 serine/threonine protein phosphatase with EF-hand mo... 334 2e-91
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 227 3e-59
gi|57222565 protein phosphatase 2, catalytic subunit, beta isofo... 137 3e-32
gi|4758952 protein phosphatase 2, catalytic subunit, beta isofor... 137 3e-32
gi|56790945 protein phosphatase 1, catalytic subunit, alpha isof... 135 1e-31
gi|46249376 protein phosphatase 1, catalytic subunit, beta isofo... 135 1e-31
gi|4506003 protein phosphatase 1, catalytic subunit, alpha isofo... 135 1e-31
gi|4506005 protein phosphatase 1, catalytic subunit, beta isofor... 135 1e-31
gi|4506007 protein phosphatase 1, catalytic subunit, gamma isofo... 134 2e-31
gi|4506017 protein phosphatase 2, catalytic subunit, alpha isofo... 133 6e-31
gi|45827798 protein phosphatase 1, catalytic subunit, alpha isof... 130 4e-30
gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens] 122 1e-27
gi|194688147 protein phosphatase 3, catalytic subunit, alpha iso... 115 1e-25
gi|6715568 protein phosphatase 3, catalytic subunit, alpha isofo... 115 1e-25
gi|183603929 protein phosphatase 6, catalytic subunit isoform a ... 114 3e-25
gi|4506029 protein phosphatase 6, catalytic subunit isoform b [H... 114 3e-25
gi|215272354 protein phosphatase 3, catalytic subunit, beta isof... 114 4e-25
gi|215272352 protein phosphatase 3, catalytic subunit, beta isof... 114 4e-25
gi|11036640 protein phosphatase 3, catalytic subunit, beta isofo... 114 4e-25
gi|194688149 protein phosphatase 3, catalytic subunit, alpha iso... 111 2e-24
gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Hom... 108 2e-23
gi|183603931 protein phosphatase 6, catalytic subunit isoform c ... 95 2e-19
gi|239752750 PREDICTED: similar to protein phosphatase 2, cataly... 48 3e-05
gi|239747318 PREDICTED: similar to protein phosphatase 2, cataly... 48 3e-05
gi|239741140 PREDICTED: similar to protein phosphatase 2, cataly... 48 3e-05
gi|76056882 calcium binding protein 1 isoform 3 [Homo sapiens] 44 5e-04
gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial... 42 0.001
>gi|23312380 protein phosphatase with EF hand calcium-binding domain
1 isoform 1 [Homo sapiens]
Length = 653
Score = 1340 bits (3469), Expect = 0.0
Identities = 653/653 (100%), Positives = 653/653 (100%)
Query: 1 MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLS 60
MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLS
Sbjct: 1 MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLS 60
Query: 61 TFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTD 120
TFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTD
Sbjct: 61 TFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTD 120
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL
Sbjct: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN
Sbjct: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRV 300
LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRV
Sbjct: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRV 300
Query: 301 ERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDIL 360
ERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDIL
Sbjct: 301 ERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDIL 360
Query: 361 WSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVT 420
WSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVT
Sbjct: 361 WSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVT 420
Query: 421 IFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKILRER 480
IFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKILRER
Sbjct: 421 IFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKILRER 480
Query: 481 VISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNGNVEY 540
VISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNGNVEY
Sbjct: 481 VISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNGNVEY 540
Query: 541 MSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWKLFSS 600
MSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWKLFSS
Sbjct: 541 MSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWKLFSS 600
Query: 601 HYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHRYEDLMKPDVTNLG 653
HYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHRYEDLMKPDVTNLG
Sbjct: 601 HYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHRYEDLMKPDVTNLG 653
>gi|23312374 protein phosphatase with EF hand calcium-binding domain
1 isoform 1b [Homo sapiens]
Length = 625
Score = 1265 bits (3273), Expect = 0.0
Identities = 625/653 (95%), Positives = 625/653 (95%), Gaps = 28/653 (4%)
Query: 1 MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLS 60
MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLS
Sbjct: 1 MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLS 60
Query: 61 TFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTD 120
TFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTD
Sbjct: 61 TFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTD 120
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL
Sbjct: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN
Sbjct: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRV 300
LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRV
Sbjct: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRV 300
Query: 301 ERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDIL 360
ERNKMKSVLIPPTETNRDHDTDSKHNK IIDIL
Sbjct: 301 ERNKMKSVLIPPTETNRDHDTDSKHNK----------------------------IIDIL 332
Query: 361 WSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVT 420
WSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVT
Sbjct: 333 WSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVT 392
Query: 421 IFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKILRER 480
IFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKILRER
Sbjct: 393 IFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKILRER 452
Query: 481 VISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNGNVEY 540
VISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNGNVEY
Sbjct: 453 VISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNGNVEY 512
Query: 541 MSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWKLFSS 600
MSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWKLFSS
Sbjct: 513 MSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWKLFSS 572
Query: 601 HYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHRYEDLMKPDVTNLG 653
HYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHRYEDLMKPDVTNLG
Sbjct: 573 HYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHRYEDLMKPDVTNLG 625
>gi|23312378 protein phosphatase with EF hand calcium-binding domain
1 isoform 3 [Homo sapiens]
Length = 591
Score = 735 bits (1898), Expect = 0.0
Identities = 359/381 (94%), Positives = 364/381 (95%), Gaps = 4/381 (1%)
Query: 1 MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLS 60
MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLS
Sbjct: 1 MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLS 60
Query: 61 TFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTD 120
TFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTD
Sbjct: 61 TFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTD 120
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL
Sbjct: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN
Sbjct: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRV 300
LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRV
Sbjct: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRV 300
Query: 301 ERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDIL 360
ERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQ++ I
Sbjct: 301 ERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQVVTIF 360
Query: 361 ----WSDPRGKNGCFPNTCRG 377
+ + G + C G
Sbjct: 361 SASNYYEEGSNRGAYIKLCSG 381
Score = 476 bits (1225), Expect = e-134
Identities = 236/237 (99%), Positives = 237/237 (100%)
Query: 417 KVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKI 476
+VVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKI
Sbjct: 355 QVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKI 414
Query: 477 LRERVISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNG 536
LRERVISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNG
Sbjct: 415 LRERVISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNG 474
Query: 537 NVEYMSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWK 596
NVEYMSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWK
Sbjct: 475 NVEYMSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWK 534
Query: 597 LFSSHYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHRYEDLMKPDVTNLG 653
LFSSHYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHRYEDLMKPDVTNLG
Sbjct: 535 LFSSHYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHRYEDLMKPDVTNLG 591
>gi|23312386 serine/threonine protein phosphatase with EF-hand
motifs 2 [Homo sapiens]
Length = 753
Score = 334 bits (856), Expect = 2e-91
Identities = 160/319 (50%), Positives = 225/319 (70%), Gaps = 6/319 (1%)
Query: 11 RRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLSTFFSFMLENY 70
+ ++ + +AA +IQ WYR Y ARL+ R+ +IFQSIEYA +Q Q++L FFS++++++
Sbjct: 14 QNAERAFKAAALIQRWYRRYVARLEMRRRCTWSIFQSIEYAGQQDQVKLHDFFSYLMDHF 73
Query: 71 ---THIHKEELE--LRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTDIDLLL 125
+H ++ L + +M+ DY +SI+VPDSY GPRL FPL L+
Sbjct: 74 IPSSHNDRDFLTRIFTEDRFAQDSEMKKCSDY-ESIEVPDSYTGPRLSFPLLPDHATALV 132
Query: 126 EAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFY 185
EAF+ +Q LHA YVL +L+ETKK L Q+PN + T S+E+T+CGDLHG+LDDL IFY
Sbjct: 133 EAFRLKQQLHARYVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFIFY 192
Query: 186 KNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGF 245
KNGLPS YVFNGDFVDRGK+S+EILMIL LVYP + HLNRGNHED M+NLRYGF
Sbjct: 193 KNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGF 252
Query: 246 TKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKM 305
TKE+++KYK+HGK IL+ L++ + WLP+ T++D ++L++HGG+S+ TDL LL ++ER+K+
Sbjct: 253 TKEVMNKYKVHGKEILRTLQDVFCWLPLATLIDEKVLILHGGVSDITDLELLDKIERSKI 312
Query: 306 KSVLIPPTETNRDHDTDSK 324
S + T + + K
Sbjct: 313 VSTMRCKTRQKSEKQMEEK 331
Score = 328 bits (840), Expect = 1e-89
Identities = 159/293 (54%), Positives = 203/293 (69%), Gaps = 1/293 (0%)
Query: 349 TEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPE 408
T+ EW Q++DILWSDP + GC NT RGGGCYFGPDVT ++L KY ++ LIRSHECKPE
Sbjct: 434 TQEEWRQVVDILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPE 493
Query: 409 GYEICHDGKVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDT 468
GYE CH+ KV+TIFSASNYYE GSNRGAY+KL TP QYQ K T +RQR+
Sbjct: 494 GYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANKVTHTLTMRQRISR 553
Query: 469 MENSAIKILRERVISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSN 528
+E SA++ LRE++ + SDL F+ D K G +++S WA +E++L L LPWR L
Sbjct: 554 VEESALRALREKLFAHSSDLLSEFKKHDADKVGLITLSDWAAAVESVLHLGLPWRMLRPQ 613
Query: 529 LVNIDQNGNVEYMSSFQNIRIEKPVQE-AHSTLVETLYRYRSDLEIIFNAIDTDHSGLIS 587
LVN + +EY S +N+ E+ +E S+L+ETLYR RS+LE IF ID+DHSG IS
Sbjct: 614 LVNSSADNMLEYKSWLKNLAKEQLSRENIQSSLLETLYRNRSNLETIFRIIDSDHSGFIS 673
Query: 588 VEEFRAMWKLFSSHYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHR 640
++EFR WKLFSSH N+ I D + LA +D NKDG ID NEFL+AF +V +
Sbjct: 674 LDEFRQTWKLFSSHMNIDITDDCICDLARSIDFNKDGHIDINEFLEAFRLVEK 726
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 227 bits (578), Expect = 3e-59
Identities = 129/379 (34%), Positives = 204/379 (53%), Gaps = 49/379 (12%)
Query: 86 ESEQDMRDRWDYVDSIDVPDSYNGPRLQF-PLTCTDIDLLLEAFKEQQILHAHYVLEVLF 144
E ++ + D D ++S+ + D Y+GP+L+ +T + + L++ +K+Q+ LH ++L
Sbjct: 156 EHKRSVVDSLD-IESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILV 214
Query: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204
+ K+VL ++ ++++T+CGD HG+ DL IF NGLPSE NPY+FNGDFVD
Sbjct: 215 QVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVD 274
Query: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264
RG S+E+++ L L+YP+ HL RGNHE MN YGF E+ KY ++ ++
Sbjct: 275 RGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYT---AQMYELF 331
Query: 265 EEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSK 324
E + WLP+ ++ ++L++HGG+
Sbjct: 332 SEVFEWLPLAQCINGKVLIMHGGL------------------------------------ 355
Query: 325 HNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGP 384
++ GVT + +I+ N P + + D+LWSDP+ +NG + RG C FGP
Sbjct: 356 FSEDGVTLDDIRKIERNRQPPDS------GPMCDLLWSDPQPQNGRSISK-RGVSCQFGP 408
Query: 385 DVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKL-CSG 443
DVT L + L +IRSHE K EGYE+ H G+ VT+FSA NY ++ N+ +YI L S
Sbjct: 409 DVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSD 468
Query: 444 TTPRFFQYQVTKATCFQPL 462
P+F Q+ +P+
Sbjct: 469 LRPQFHQFTAVPHPNVKPM 487
>gi|57222565 protein phosphatase 2, catalytic subunit, beta isoform
[Homo sapiens]
Length = 309
Score = 137 bits (345), Expect = 3e-32
Identities = 99/334 (29%), Positives = 154/334 (46%), Gaps = 55/334 (16%)
Query: 120 DIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDD 179
++D +E E + L+ + V + + K++L + N ++ VT+CGD+HG+ D
Sbjct: 9 ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCP----VTVCGDVHGQFHD 64
Query: 180 LFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMM 239
L +F G + N Y+F GD+VDRG S+E + +L + YP + + RGNHE +
Sbjct: 65 LMELFRIGGKSPDTN-YLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQI 123
Query: 240 NLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHR 299
YGF E L KY + + + + +LP+ +VD +I +HGG+S + D L H
Sbjct: 124 TQVYGFYDECLRKY--GNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSID-TLDHI 180
Query: 300 VERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDI 359
++++ V HE + D+
Sbjct: 181 RALDRLQEV-----------------------------------------PHE-GPMCDL 198
Query: 360 LWSDP--RGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGK 417
LWSDP RG G P RG G FG D++ + L ++ R+H+ EGY CHD
Sbjct: 199 LWSDPDDRGGWGISP---RGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRN 255
Query: 418 VVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQY 451
VVTIFSA NY N+ A ++L F Q+
Sbjct: 256 VVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQF 289
>gi|4758952 protein phosphatase 2, catalytic subunit, beta isoform
[Homo sapiens]
Length = 309
Score = 137 bits (345), Expect = 3e-32
Identities = 99/334 (29%), Positives = 154/334 (46%), Gaps = 55/334 (16%)
Query: 120 DIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDD 179
++D +E E + L+ + V + + K++L + N ++ VT+CGD+HG+ D
Sbjct: 9 ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCP----VTVCGDVHGQFHD 64
Query: 180 LFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMM 239
L +F G + N Y+F GD+VDRG S+E + +L + YP + + RGNHE +
Sbjct: 65 LMELFRIGGKSPDTN-YLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQI 123
Query: 240 NLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHR 299
YGF E L KY + + + + +LP+ +VD +I +HGG+S + D L H
Sbjct: 124 TQVYGFYDECLRKY--GNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSID-TLDHI 180
Query: 300 VERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDI 359
++++ V HE + D+
Sbjct: 181 RALDRLQEV-----------------------------------------PHE-GPMCDL 198
Query: 360 LWSDP--RGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGK 417
LWSDP RG G P RG G FG D++ + L ++ R+H+ EGY CHD
Sbjct: 199 LWSDPDDRGGWGISP---RGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRN 255
Query: 418 VVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQY 451
VVTIFSA NY N+ A ++L F Q+
Sbjct: 256 VVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQF 289
>gi|56790945 protein phosphatase 1, catalytic subunit, alpha isoform
3 [Homo sapiens]
Length = 341
Score = 135 bits (340), Expect = 1e-31
Identities = 88/272 (32%), Positives = 132/272 (48%), Gaps = 47/272 (17%)
Query: 169 ICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLH 228
ICGD+HG+ DL +F G P E N Y+F GD+VDRGK S+E + +L + YP +
Sbjct: 72 ICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 130
Query: 229 LNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGI 288
L RGNHE +N YGF E +Y + ++ + + + LPI IVD +I HGG+
Sbjct: 131 LLRGNHECASINRIYGFYDECKRRYNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGL 187
Query: 289 SETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHL 348
S DL + ++ R ++ PT+ P + L
Sbjct: 188 S--PDLQSMEQIRR------IMRPTDV----------------------------PDQGL 211
Query: 349 TEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPE 408
+ D+LWSDP + RG FG +V +K L+K+ L ++ R+H+ +
Sbjct: 212 -------LCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVED 264
Query: 409 GYEICHDGKVVTIFSASNYYEEGSNRGAYIKL 440
GYE ++VT+FSA NY E N GA + +
Sbjct: 265 GYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSV 296
>gi|46249376 protein phosphatase 1, catalytic subunit, beta isoform
1 [Homo sapiens]
Length = 327
Score = 135 bits (340), Expect = 1e-31
Identities = 88/272 (32%), Positives = 130/272 (47%), Gaps = 47/272 (17%)
Query: 169 ICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLH 228
ICGD+HG+ DL +F G P E N Y+F GD+VDRGK S+E + +L + YP +
Sbjct: 60 ICGDIHGQYTDLLRLFEYGGFPPEAN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 118
Query: 229 LNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGI 288
L RGNHE +N YGF E ++ + ++ + + + LPI IVD +I HGG+
Sbjct: 119 LLRGNHECASINRIYGFYDECKRRFNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGL 175
Query: 289 SETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHL 348
S DL + ++ R ++ PT+ P L
Sbjct: 176 S--PDLQSMEQIRR------IMRPTDV----------------------------PDTGL 199
Query: 349 TEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPE 408
+ D+LWSDP + RG FG DV SK LN++ L ++ R+H+ +
Sbjct: 200 -------LCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVED 252
Query: 409 GYEICHDGKVVTIFSASNYYEEGSNRGAYIKL 440
GYE ++VT+FSA NY E N G + +
Sbjct: 253 GYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSV 284
>gi|4506003 protein phosphatase 1, catalytic subunit, alpha isoform
1 [Homo sapiens]
Length = 330
Score = 135 bits (340), Expect = 1e-31
Identities = 88/272 (32%), Positives = 132/272 (48%), Gaps = 47/272 (17%)
Query: 169 ICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLH 228
ICGD+HG+ DL +F G P E N Y+F GD+VDRGK S+E + +L + YP +
Sbjct: 61 ICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 119
Query: 229 LNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGI 288
L RGNHE +N YGF E +Y + ++ + + + LPI IVD +I HGG+
Sbjct: 120 LLRGNHECASINRIYGFYDECKRRYNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGL 176
Query: 289 SETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHL 348
S DL + ++ R ++ PT+ P + L
Sbjct: 177 S--PDLQSMEQIRR------IMRPTDV----------------------------PDQGL 200
Query: 349 TEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPE 408
+ D+LWSDP + RG FG +V +K L+K+ L ++ R+H+ +
Sbjct: 201 -------LCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVED 253
Query: 409 GYEICHDGKVVTIFSASNYYEEGSNRGAYIKL 440
GYE ++VT+FSA NY E N GA + +
Sbjct: 254 GYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSV 285
>gi|4506005 protein phosphatase 1, catalytic subunit, beta isoform 1
[Homo sapiens]
Length = 327
Score = 135 bits (340), Expect = 1e-31
Identities = 88/272 (32%), Positives = 130/272 (47%), Gaps = 47/272 (17%)
Query: 169 ICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLH 228
ICGD+HG+ DL +F G P E N Y+F GD+VDRGK S+E + +L + YP +
Sbjct: 60 ICGDIHGQYTDLLRLFEYGGFPPEAN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 118
Query: 229 LNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGI 288
L RGNHE +N YGF E ++ + ++ + + + LPI IVD +I HGG+
Sbjct: 119 LLRGNHECASINRIYGFYDECKRRFNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGL 175
Query: 289 SETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHL 348
S DL + ++ R ++ PT+ P L
Sbjct: 176 S--PDLQSMEQIRR------IMRPTDV----------------------------PDTGL 199
Query: 349 TEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPE 408
+ D+LWSDP + RG FG DV SK LN++ L ++ R+H+ +
Sbjct: 200 -------LCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVED 252
Query: 409 GYEICHDGKVVTIFSASNYYEEGSNRGAYIKL 440
GYE ++VT+FSA NY E N G + +
Sbjct: 253 GYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSV 284
>gi|4506007 protein phosphatase 1, catalytic subunit, gamma isoform
[Homo sapiens]
Length = 323
Score = 134 bits (338), Expect = 2e-31
Identities = 88/272 (32%), Positives = 132/272 (48%), Gaps = 47/272 (17%)
Query: 169 ICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLH 228
ICGD+HG+ DL +F G P E N Y+F GD+VDRGK S+E + +L + YP +
Sbjct: 61 ICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 119
Query: 229 LNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGI 288
L RGNHE +N YGF E +Y + ++ + + + LPI IVD +I HGG+
Sbjct: 120 LLRGNHECASINRIYGFYDECKRRYNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGL 176
Query: 289 SETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHL 348
S DL + ++ R ++ PT+ P + L
Sbjct: 177 S--PDLQSMEQIRR------IMRPTDV----------------------------PDQGL 200
Query: 349 TEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPE 408
+ D+LWSDP + RG FG +V +K L+K+ L ++ R+H+ +
Sbjct: 201 -------LCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVED 253
Query: 409 GYEICHDGKVVTIFSASNYYEEGSNRGAYIKL 440
GYE ++VT+FSA NY E N GA + +
Sbjct: 254 GYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSV 285
>gi|4506017 protein phosphatase 2, catalytic subunit, alpha isoform
[Homo sapiens]
Length = 309
Score = 133 bits (334), Expect = 6e-31
Identities = 98/334 (29%), Positives = 151/334 (45%), Gaps = 55/334 (16%)
Query: 120 DIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDD 179
++D +E E + L V + + K++L + N ++ VT+CGD+HG+ D
Sbjct: 9 ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCP----VTVCGDVHGQFHD 64
Query: 180 LFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMM 239
L +F G + N Y+F GD+VDRG S+E + +L + Y + + RGNHE +
Sbjct: 65 LMELFRIGGKSPDTN-YLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQI 123
Query: 240 NLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHR 299
YGF E L KY + + + + +LP+ +VD +I +HGG+S + D L H
Sbjct: 124 TQVYGFYDECLRKY--GNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSID-TLDHI 180
Query: 300 VERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDI 359
++++ V HE + D+
Sbjct: 181 RALDRLQEV-----------------------------------------PHE-GPMCDL 198
Query: 360 LWSDP--RGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGK 417
LWSDP RG G P RG G FG D++ + L ++ R+H+ EGY CHD
Sbjct: 199 LWSDPDDRGGWGISP---RGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRN 255
Query: 418 VVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQY 451
VVTIFSA NY N+ A ++L F Q+
Sbjct: 256 VVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQF 289
>gi|45827798 protein phosphatase 1, catalytic subunit, alpha isoform
2 [Homo sapiens]
Length = 286
Score = 130 bits (327), Expect = 4e-30
Identities = 86/270 (31%), Positives = 130/270 (48%), Gaps = 47/270 (17%)
Query: 171 GDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLN 230
GD+HG+ DL +F G P E N Y+F GD+VDRGK S+E + +L + YP + L
Sbjct: 19 GDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL 77
Query: 231 RGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISE 290
RGNHE +N YGF E +Y + ++ + + + LPI IVD +I HGG+S
Sbjct: 78 RGNHECASINRIYGFYDECKRRYNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGLS- 133
Query: 291 TTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTE 350
DL + ++ R ++ PT+ P + L
Sbjct: 134 -PDLQSMEQIRR------IMRPTDV----------------------------PDQGL-- 156
Query: 351 HEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGY 410
+ D+LWSDP + RG FG +V +K L+K+ L ++ R+H+ +GY
Sbjct: 157 -----LCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGY 211
Query: 411 EICHDGKVVTIFSASNYYEEGSNRGAYIKL 440
E ++VT+FSA NY E N GA + +
Sbjct: 212 EFFAKRQLVTLFSAPNYCGEFDNAGAMMSV 241
>gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens]
Length = 307
Score = 122 bits (305), Expect = 1e-27
Identities = 89/323 (27%), Positives = 149/323 (46%), Gaps = 53/323 (16%)
Query: 119 TDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLD 178
+D+D +E + +++ V + + +++L + N + + VT+CGD+HG+
Sbjct: 5 SDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSP----VTVCGDIHGQFY 60
Query: 179 DLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFM 238
DL +F G E N Y+F GDFVDRG S+E ++L + YP+ + L RGNHE
Sbjct: 61 DLKELFRVGGDVPETN-YLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ 119
Query: 239 MNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTD-LNLL 297
+ YGF E L KY + + E + +L + I+D +I +HGG+S + L+ +
Sbjct: 120 ITQVYGFYDECLRKY--GSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQI 177
Query: 298 HRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQII 357
++R + +P HD +
Sbjct: 178 RTIDRKQE----VP-------HD---------------------------------GPMC 193
Query: 358 DILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGK 417
D+LWSDP G + + RG G FG DV ++ + M+ R+H+ EGY+ +
Sbjct: 194 DLLWSDPEDTTG-WGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNET 252
Query: 418 VVTIFSASNYYEEGSNRGAYIKL 440
V+T++SA NY N A ++L
Sbjct: 253 VLTVWSAPNYCYRCGNVAAILEL 275
>gi|194688147 protein phosphatase 3, catalytic subunit, alpha
isoform isoform 2 [Homo sapiens]
Length = 511
Score = 115 bits (288), Expect = 1e-25
Identities = 90/333 (27%), Positives = 147/333 (44%), Gaps = 66/333 (19%)
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
+D+L ++ L L ++ E +L+Q N I VT+CGD+HG+ DL
Sbjct: 43 VDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAP----VTVCGDIHGQFFDL 98
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
+F G P+ Y+F GD+VDRG SIE ++ L ++YP L L RGNHE +
Sbjct: 99 MKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLT 157
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
+ F +E KY +R+ + + LP+ +++ + L +HGG+S E L+ + +
Sbjct: 158 EYFTFKQECKIKY---SERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRK 214
Query: 300 VERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDI 359
++R K PP A+G + DI
Sbjct: 215 LDRFKE-----PP---------------------AYG------------------PMCDI 230
Query: 360 LWSDP-------RGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEI 412
LWSDP + + NT RG ++ + L L ++R+HE + GY +
Sbjct: 231 LWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRM 290
Query: 413 CHDGK------VVTIFSASNYYEEGSNRGAYIK 439
+ ++TIFSA NY + +N+ A +K
Sbjct: 291 YRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLK 323
>gi|6715568 protein phosphatase 3, catalytic subunit, alpha isoform
isoform 1 [Homo sapiens]
Length = 521
Score = 115 bits (288), Expect = 1e-25
Identities = 90/333 (27%), Positives = 147/333 (44%), Gaps = 66/333 (19%)
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
+D+L ++ L L ++ E +L+Q N I VT+CGD+HG+ DL
Sbjct: 43 VDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAP----VTVCGDIHGQFFDL 98
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
+F G P+ Y+F GD+VDRG SIE ++ L ++YP L L RGNHE +
Sbjct: 99 MKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLT 157
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
+ F +E KY +R+ + + LP+ +++ + L +HGG+S E L+ + +
Sbjct: 158 EYFTFKQECKIKY---SERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRK 214
Query: 300 VERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDI 359
++R K PP A+G + DI
Sbjct: 215 LDRFKE-----PP---------------------AYG------------------PMCDI 230
Query: 360 LWSDP-------RGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEI 412
LWSDP + + NT RG ++ + L L ++R+HE + GY +
Sbjct: 231 LWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRM 290
Query: 413 CHDGK------VVTIFSASNYYEEGSNRGAYIK 439
+ ++TIFSA NY + +N+ A +K
Sbjct: 291 YRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLK 323
>gi|183603929 protein phosphatase 6, catalytic subunit isoform a
[Homo sapiens]
Length = 342
Score = 114 bits (285), Expect = 3e-25
Identities = 79/265 (29%), Positives = 122/265 (46%), Gaps = 49/265 (18%)
Query: 164 SKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVY 223
S VT+CGD+HG+ DL +F G + N Y+F GDFVDRG S+E L +
Sbjct: 82 STPVTVCGDIHGQFYDLCELFRTGGQVPDTN-YIFMGDFVDRGYYSLETFTYLLALKAKW 140
Query: 224 PNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILV 283
P+ + L RGNHE + YGF E KY + + + L + ++D +IL
Sbjct: 141 PDRITLLRGNHESRQITQVYGFYDECQTKY--GNANAWRYCTKVFDMLTVAALIDEQILC 198
Query: 284 IHGGIS-ETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNG 342
+HGG+S + L+ + +ERN+ I G
Sbjct: 199 VHGGLSPDIKTLDQIRTIERNQ--------------------------------EIPHKG 226
Query: 343 SPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRS 402
+ D++WSDP + + + RG G FG VT++ ++ LK++ R+
Sbjct: 227 A------------FCDLVWSDPEDVD-TWAISPRGAGWLFGAKVTNEFVHINNLKLICRA 273
Query: 403 HECKPEGYEICHDGKVVTIFSASNY 427
H+ EGY+ D K+VT++SA NY
Sbjct: 274 HQLVHEGYKFMFDEKLVTVWSAPNY 298
>gi|4506029 protein phosphatase 6, catalytic subunit isoform b [Homo
sapiens]
Length = 305
Score = 114 bits (285), Expect = 3e-25
Identities = 79/265 (29%), Positives = 122/265 (46%), Gaps = 49/265 (18%)
Query: 164 SKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVY 223
S VT+CGD+HG+ DL +F G + N Y+F GDFVDRG S+E L +
Sbjct: 45 STPVTVCGDIHGQFYDLCELFRTGGQVPDTN-YIFMGDFVDRGYYSLETFTYLLALKAKW 103
Query: 224 PNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILV 283
P+ + L RGNHE + YGF E KY + + + L + ++D +IL
Sbjct: 104 PDRITLLRGNHESRQITQVYGFYDECQTKY--GNANAWRYCTKVFDMLTVAALIDEQILC 161
Query: 284 IHGGIS-ETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNG 342
+HGG+S + L+ + +ERN+ I G
Sbjct: 162 VHGGLSPDIKTLDQIRTIERNQ--------------------------------EIPHKG 189
Query: 343 SPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRS 402
+ D++WSDP + + + RG G FG VT++ ++ LK++ R+
Sbjct: 190 A------------FCDLVWSDPEDVD-TWAISPRGAGWLFGAKVTNEFVHINNLKLICRA 236
Query: 403 HECKPEGYEICHDGKVVTIFSASNY 427
H+ EGY+ D K+VT++SA NY
Sbjct: 237 HQLVHEGYKFMFDEKLVTVWSAPNY 261
>gi|215272354 protein phosphatase 3, catalytic subunit, beta isoform
c [Homo sapiens]
Length = 515
Score = 114 bits (284), Expect = 4e-25
Identities = 86/333 (25%), Positives = 148/333 (44%), Gaps = 66/333 (19%)
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
+D+L ++ + L ++ E +L++ ++ +T+CGD+HG+ DL
Sbjct: 52 VDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAP----ITVCGDIHGQFFDL 107
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
+F G P+ Y+F GD+VDRG SIE ++ L V ++YP+ L L RGNHE +
Sbjct: 108 MKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLT 166
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
+ F +E KY +R+ + E + LP+ +++ + L +HGG+S E L+ + R
Sbjct: 167 EYFTFKQECKIKY---SERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRR 223
Query: 300 VERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDI 359
++R K PP + + D+
Sbjct: 224 LDRFKE-----PPA---------------------------------------FGPMCDL 239
Query: 360 LWSDP-------RGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEI 412
LWSDP + + NT RG ++ + L L +IR+HE + GY +
Sbjct: 240 LWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRM 299
Query: 413 CHDGK------VVTIFSASNYYEEGSNRGAYIK 439
+ ++TIFSA NY + +N+ A +K
Sbjct: 300 YRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLK 332
>gi|215272352 protein phosphatase 3, catalytic subunit, beta isoform
a [Homo sapiens]
Length = 525
Score = 114 bits (284), Expect = 4e-25
Identities = 86/333 (25%), Positives = 148/333 (44%), Gaps = 66/333 (19%)
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
+D+L ++ + L ++ E +L++ ++ +T+CGD+HG+ DL
Sbjct: 52 VDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAP----ITVCGDIHGQFFDL 107
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
+F G P+ Y+F GD+VDRG SIE ++ L V ++YP+ L L RGNHE +
Sbjct: 108 MKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLT 166
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
+ F +E KY +R+ + E + LP+ +++ + L +HGG+S E L+ + R
Sbjct: 167 EYFTFKQECKIKY---SERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRR 223
Query: 300 VERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDI 359
++R K PP + + D+
Sbjct: 224 LDRFKE-----PPA---------------------------------------FGPMCDL 239
Query: 360 LWSDP-------RGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEI 412
LWSDP + + NT RG ++ + L L +IR+HE + GY +
Sbjct: 240 LWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRM 299
Query: 413 CHDGK------VVTIFSASNYYEEGSNRGAYIK 439
+ ++TIFSA NY + +N+ A +K
Sbjct: 300 YRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLK 332
>gi|11036640 protein phosphatase 3, catalytic subunit, beta isoform
b [Homo sapiens]
Length = 524
Score = 114 bits (284), Expect = 4e-25
Identities = 86/333 (25%), Positives = 148/333 (44%), Gaps = 66/333 (19%)
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
+D+L ++ + L ++ E +L++ ++ +T+CGD+HG+ DL
Sbjct: 52 VDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAP----ITVCGDIHGQFFDL 107
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
+F G P+ Y+F GD+VDRG SIE ++ L V ++YP+ L L RGNHE +
Sbjct: 108 MKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLT 166
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
+ F +E KY +R+ + E + LP+ +++ + L +HGG+S E L+ + R
Sbjct: 167 EYFTFKQECKIKY---SERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRR 223
Query: 300 VERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDI 359
++R K PP + + D+
Sbjct: 224 LDRFKE-----PPA---------------------------------------FGPMCDL 239
Query: 360 LWSDP-------RGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEI 412
LWSDP + + NT RG ++ + L L +IR+HE + GY +
Sbjct: 240 LWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRM 299
Query: 413 CHDGK------VVTIFSASNYYEEGSNRGAYIK 439
+ ++TIFSA NY + +N+ A +K
Sbjct: 300 YRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLK 332
>gi|194688149 protein phosphatase 3, catalytic subunit, alpha
isoform isoform 3 [Homo sapiens]
Length = 469
Score = 111 bits (278), Expect = 2e-24
Identities = 88/328 (26%), Positives = 144/328 (43%), Gaps = 66/328 (20%)
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
+D+L ++ L L ++ E +L+Q N I VT+CGD+HG+ DL
Sbjct: 43 VDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAP----VTVCGDIHGQFFDL 98
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
+F G P+ Y+F GD+VDRG SIE ++ L ++YP L L RGNHE +
Sbjct: 99 MKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLT 157
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
+ F +E KY +R+ + + LP+ +++ + L +HGG+S E L+ + +
Sbjct: 158 EYFTFKQECKIKY---SERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRK 214
Query: 300 VERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDI 359
++R K PP A+G + DI
Sbjct: 215 LDRFKE-----PP---------------------AYG------------------PMCDI 230
Query: 360 LWSDP-------RGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEI 412
LWSDP + + NT RG ++ + L L ++R+HE + GY +
Sbjct: 231 LWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRM 290
Query: 413 CHDGK------VVTIFSASNYYEEGSNR 434
+ ++TIFSA NY + +N+
Sbjct: 291 YRKSQTTGFPSLITIFSAPNYLDVYNNK 318
>gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Homo
sapiens]
Length = 512
Score = 108 bits (269), Expect = 2e-23
Identities = 85/333 (25%), Positives = 143/333 (42%), Gaps = 66/333 (19%)
Query: 121 IDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL 180
+D+L ++ L L+++ + +L+Q + +T+CGD+HG+ DL
Sbjct: 39 VDVLKNHLVKEGRLEEEVALKIINDGAAILRQEKTMIEVDAP----ITVCGDIHGQFFDL 94
Query: 181 FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN 240
+F G PS Y+F GD+VDRG SIE ++ L + +P L L RGNHE +
Sbjct: 95 MKLFEVGGSPSNTR-YLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLT 153
Query: 241 LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHR 299
+ F +E KY +++ E + LP+ +++ + L +HGG+S E T L+ + +
Sbjct: 154 DYFTFKQECRIKY---SEQVYDACMETFDCLPLAALLNQQFLCVHGGMSPEITSLDDIRK 210
Query: 300 VERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDI 359
++R PP + + D+
Sbjct: 211 LDR-----FTEPPA---------------------------------------FGPVCDL 226
Query: 360 LWSDPRGKNG-------CFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEI 412
LWSDP G NT RG ++ + L L +IR+HE + GY +
Sbjct: 227 LWSDPSEDYGNEKTLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRM 286
Query: 413 CHDGK------VVTIFSASNYYEEGSNRGAYIK 439
+ ++TIFSA NY + +N+ A +K
Sbjct: 287 YRKSQATGFPSLITIFSAPNYLDVYNNKAAVLK 319
>gi|183603931 protein phosphatase 6, catalytic subunit isoform c
[Homo sapiens]
Length = 283
Score = 94.7 bits (234), Expect = 2e-19
Identities = 72/265 (27%), Positives = 112/265 (42%), Gaps = 71/265 (26%)
Query: 164 SKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVY 223
S VT+CGD+HG+ GDFVDRG S+E L +
Sbjct: 45 STPVTVCGDIHGQ-----------------------GDFVDRGYYSLETFTYLLALKAKW 81
Query: 224 PNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILV 283
P+ + L RGNHE + YGF E KY + + + L + ++D +IL
Sbjct: 82 PDRITLLRGNHESRQITQVYGFYDECQTKY--GNANAWRYCTKVFDMLTVAALIDEQILC 139
Query: 284 IHGGIS-ETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNG 342
+HGG+S + L+ + +ERN+ I G
Sbjct: 140 VHGGLSPDIKTLDQIRTIERNQ--------------------------------EIPHKG 167
Query: 343 SPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRS 402
+ D++WSDP + + + RG G FG VT++ ++ LK++ R+
Sbjct: 168 A------------FCDLVWSDPEDVD-TWAISPRGAGWLFGAKVTNEFVHINNLKLICRA 214
Query: 403 HECKPEGYEICHDGKVVTIFSASNY 427
H+ EGY+ D K+VT++SA NY
Sbjct: 215 HQLVHEGYKFMFDEKLVTVWSAPNY 239
>gi|239752750 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 384
Score = 47.8 bits (112), Expect = 3e-05
Identities = 63/283 (22%), Positives = 95/283 (33%), Gaps = 106/283 (37%)
Query: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204
E K++L + N + VT+ GD HG+ GD++D
Sbjct: 183 EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 215
Query: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264
RG SIEI+M+L + Y + + NHE + Y +E L K HG
Sbjct: 216 RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRK---HG------- 265
Query: 265 EEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSK 324
D ++ +HGG+S + D LH +
Sbjct: 266 ---------NANGDGQLFCLHGGLSPSVD--TLHHIR----------------------- 291
Query: 325 HNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGP 384
T N +I G + D+L+SDP
Sbjct: 292 ------TLNCLQKIPHEG------------PMGDLLYSDPDDH----------------- 316
Query: 385 DVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNY 427
D + L+++ R+H+ G+ CHD VV IFS NY
Sbjct: 317 DTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNY 359
>gi|239747318 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 254
Score = 47.8 bits (112), Expect = 3e-05
Identities = 63/283 (22%), Positives = 95/283 (33%), Gaps = 106/283 (37%)
Query: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204
E K++L + N + VT+ GD HG+ GD++D
Sbjct: 62 EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 94
Query: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264
RG SIEI+M+L + Y + + NHE + Y +E L K HG
Sbjct: 95 RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRK---HG------- 144
Query: 265 EEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSK 324
D ++ +HGG+S + D LH +
Sbjct: 145 ---------NANGDGQLFCLHGGLSPSVD--TLHHIR----------------------- 170
Query: 325 HNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGP 384
T N +I G + D+L+SDP
Sbjct: 171 ------TLNCLQKIPHEG------------PMGDLLYSDPDDH----------------- 195
Query: 385 DVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNY 427
D + L+++ R+H+ G+ CHD VV IFS NY
Sbjct: 196 DTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNY 238
>gi|239741140 PREDICTED: similar to protein phosphatase 2, catalytic
subunit, alpha [Homo sapiens]
Length = 254
Score = 47.8 bits (112), Expect = 3e-05
Identities = 63/283 (22%), Positives = 95/283 (33%), Gaps = 106/283 (37%)
Query: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204
E K++L + N + VT+ GD HG+ GD++D
Sbjct: 62 EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 94
Query: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264
RG SIEI+M+L + Y + + NHE + Y +E L K HG
Sbjct: 95 RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRK---HG------- 144
Query: 265 EEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSK 324
D ++ +HGG+S + D LH +
Sbjct: 145 ---------NANGDGQLFCLHGGLSPSVD--TLHHIR----------------------- 170
Query: 325 HNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGP 384
T N +I G + D+L+SDP
Sbjct: 171 ------TLNCLQKIPHEG------------PMGDLLYSDPDDH----------------- 195
Query: 385 DVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNY 427
D + L+++ R+H+ G+ CHD VV IFS NY
Sbjct: 196 DTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNY 238
>gi|76056882 calcium binding protein 1 isoform 3 [Homo sapiens]
Length = 370
Score = 43.9 bits (102), Expect = 5e-04
Identities = 42/174 (24%), Positives = 70/174 (40%), Gaps = 11/174 (6%)
Query: 461 PLRQRVDTMENSAIKILRERVISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNL 520
P R+ M +SA R +L AF+ D K G ++ CM + +
Sbjct: 203 PFLHRLRPMLSSAFGQDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPT 262
Query: 521 PWRSLS-SNLVNIDQNGNVEYMSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAID 579
+ S +N++ G+V++ F + K + E + +L F D
Sbjct: 263 EMELIELSQQINMNLGGHVDF-DDFVELMGPKLLAETADMIGV------KELRDAFREFD 315
Query: 580 TDHSGLISVEEFRAMWKLFSSHYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLK 633
T+ G IS E R + H H D + ++ +DLN DG +DF EF++
Sbjct: 316 TNGDGEISTSELREAMRKLLGHQVGHRD---IEEIIRDVDLNGDGRVDFEEFVR 366
>gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial
[Homo sapiens]
Length = 727
Score = 42.4 bits (98), Expect = 0.001
Identities = 18/66 (27%), Positives = 39/66 (59%), Gaps = 4/66 (6%)
Query: 575 FNAIDTDHSGLISVEEFRAMWKLFSSHYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKA 634
F+ D D G I++ + + + + NV +D++ ++++ N +DLNK+G ++ NEFL+
Sbjct: 632 FHKFDADQKGFITIVDVQRVLESI----NVQMDENTLHEILNEVDLNKNGQVELNEFLQL 687
Query: 635 FYVVHR 640
+ +
Sbjct: 688 MSAIQK 693
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,560,600
Number of Sequences: 37866
Number of extensions: 1109496
Number of successful extensions: 2910
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 93
Number of HSP's that attempted gapping in prelim test: 2591
Number of HSP's gapped (non-prelim): 309
length of query: 653
length of database: 18,247,518
effective HSP length: 109
effective length of query: 544
effective length of database: 14,120,124
effective search space: 7681347456
effective search space used: 7681347456
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.