Search of human proteins with 23308585

Search of human proteins with 23308585

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23308585 G protein-coupled receptor 156 [Homo sapiens]
         (814 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23308585 G protein-coupled receptor 156 [Homo sapiens]            1652   0.0  
gi|40255245 G protein-coupled receptor 51 [Homo sapiens]              150   3e-36
gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform...   119   1e-26
gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform ...   119   1e-26
gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform ...   119   1e-26
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        50   6e-06
gi|50083281 KIAA1853 protein [Homo sapiens]                            50   8e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         46   1e-04
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             44   6e-04
gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens]           43   0.001
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]                    42   0.002
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    42   0.002
gi|110611176 glutamate receptor, metabotropic 6 precursor [Homo ...    41   0.004
gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4 ...    40   0.007
gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 ...    40   0.007
gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2 ...    40   0.007
gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [...    40   0.007
gi|238908524 hypothetical protein LOC389333 [Homo sapiens]             40   0.009
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]                40   0.011
gi|32528268 glutamate receptor, metabotropic 7 isoform b precurs...    39   0.015
gi|4504147 glutamate receptor, metabotropic 7 isoform a precurso...    39   0.015
gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3 ...    39   0.025
gi|151101459 SAPS domain family, member 1 [Homo sapiens]               39   0.025
gi|116268127 kinase non-catalytic C-lobe domain (KIND) containin...    39   0.025
gi|22035604 mitogen-activated protein kinase kinase kinase kinas...    38   0.033
gi|189011568 adenomatous polyposis coli [Homo sapiens]                 38   0.043
gi|189011566 adenomatous polyposis coli [Homo sapiens]                 38   0.043
gi|53759122 adenomatous polyposis coli [Homo sapiens]                  38   0.043
gi|116256464 hypothetical protein LOC343990 [Homo sapiens]             38   0.043
gi|14249464 zinc finger and BTB domain containing 45 [Homo sapiens]    38   0.043

>gi|23308585 G protein-coupled receptor 156 [Homo sapiens]
          Length = 814

 Score = 1652 bits (4277), Expect = 0.0
 Identities = 814/814 (100%), Positives = 814/814 (100%)

Query: 1   MEPEINCSELCDSFPGQELDRRPLHDLCKTTITSSHHSSKTISSLSPVLLGIVWTFLSCG 60
           MEPEINCSELCDSFPGQELDRRPLHDLCKTTITSSHHSSKTISSLSPVLLGIVWTFLSCG
Sbjct: 1   MEPEINCSELCDSFPGQELDRRPLHDLCKTTITSSHHSSKTISSLSPVLLGIVWTFLSCG 60

Query: 61  LLLILFFLAFTIHCRKNRIVKMSSPNLNIVTLLGSCLTYSSAYLFGIQDVLVGSSMETLI 120
           LLLILFFLAFTIHCRKNRIVKMSSPNLNIVTLLGSCLTYSSAYLFGIQDVLVGSSMETLI
Sbjct: 61  LLLILFFLAFTIHCRKNRIVKMSSPNLNIVTLLGSCLTYSSAYLFGIQDVLVGSSMETLI 120

Query: 121 QTRLSMLCIGTSLVFGPILGKSWRLYKVFTQRVPDKRVIIKDLQLLGLVAALLMADVILL 180
           QTRLSMLCIGTSLVFGPILGKSWRLYKVFTQRVPDKRVIIKDLQLLGLVAALLMADVILL
Sbjct: 121 QTRLSMLCIGTSLVFGPILGKSWRLYKVFTQRVPDKRVIIKDLQLLGLVAALLMADVILL 180

Query: 181 MTWVLTDPIQCLQILSVSMTVTGKDVSCTSTSTHFCASRYSDVWIALIWGCKGLLLLYGA 240
           MTWVLTDPIQCLQILSVSMTVTGKDVSCTSTSTHFCASRYSDVWIALIWGCKGLLLLYGA
Sbjct: 181 MTWVLTDPIQCLQILSVSMTVTGKDVSCTSTSTHFCASRYSDVWIALIWGCKGLLLLYGA 240

Query: 241 YLAGLTGHVSSPPVNQSLTIMVGVNLLVLAAGLLFVVTRYLHSWPNLVFGLTSGGIFVCT 300
           YLAGLTGHVSSPPVNQSLTIMVGVNLLVLAAGLLFVVTRYLHSWPNLVFGLTSGGIFVCT
Sbjct: 241 YLAGLTGHVSSPPVNQSLTIMVGVNLLVLAAGLLFVVTRYLHSWPNLVFGLTSGGIFVCT 300

Query: 301 TTINCFIFIPQLKQWKAFEEENQTIRRMAKYFSTPNKSFHTQYGEEENCHPRGEKSSMER 360
           TTINCFIFIPQLKQWKAFEEENQTIRRMAKYFSTPNKSFHTQYGEEENCHPRGEKSSMER
Sbjct: 301 TTINCFIFIPQLKQWKAFEEENQTIRRMAKYFSTPNKSFHTQYGEEENCHPRGEKSSMER 360

Query: 361 LLTEKNAVIESLQEQVNNAKEKIVRLMSAECTYDLPEGAAPPASSPNKDVQAVASVHTLA 420
           LLTEKNAVIESLQEQVNNAKEKIVRLMSAECTYDLPEGAAPPASSPNKDVQAVASVHTLA
Sbjct: 361 LLTEKNAVIESLQEQVNNAKEKIVRLMSAECTYDLPEGAAPPASSPNKDVQAVASVHTLA 420

Query: 421 AAQGPSGHLSDFQNDPGMAARDSQCTSGPSSYAQSLEGPGKDSSFSPGKEEKISDSKDFS 480
           AAQGPSGHLSDFQNDPGMAARDSQCTSGPSSYAQSLEGPGKDSSFSPGKEEKISDSKDFS
Sbjct: 421 AAQGPSGHLSDFQNDPGMAARDSQCTSGPSSYAQSLEGPGKDSSFSPGKEEKISDSKDFS 480

Query: 481 DHLDSGCSQKPWTEQSLGPERGDQVPMNPSQSLLPDRGGSDPQRQRHLENSEEPPERRSR 540
           DHLDSGCSQKPWTEQSLGPERGDQVPMNPSQSLLPDRGGSDPQRQRHLENSEEPPERRSR
Sbjct: 481 DHLDSGCSQKPWTEQSLGPERGDQVPMNPSQSLLPDRGGSDPQRQRHLENSEEPPERRSR 540

Query: 541 VSSVIREKLQEVLQDLGLGPEASLSTAPSCHQQTWKNSAAFSPQKMPLSKELGFSPYMVR 600
           VSSVIREKLQEVLQDLGLGPEASLSTAPSCHQQTWKNSAAFSPQKMPLSKELGFSPYMVR
Sbjct: 541 VSSVIREKLQEVLQDLGLGPEASLSTAPSCHQQTWKNSAAFSPQKMPLSKELGFSPYMVR 600

Query: 601 RRRAAQRARSHFPGSAPSSVGHRANRTVPGAHSRLHVQNGDSPSLAPQTTDSRVRRPSSR 660
           RRRAAQRARSHFPGSAPSSVGHRANRTVPGAHSRLHVQNGDSPSLAPQTTDSRVRRPSSR
Sbjct: 601 RRRAAQRARSHFPGSAPSSVGHRANRTVPGAHSRLHVQNGDSPSLAPQTTDSRVRRPSSR 660

Query: 661 KPSLPSDPQDRPGTLEGSKQSQTEPEGARGSKAAFLRQPSGSGRAPSPAAPCLSKASPDL 720
           KPSLPSDPQDRPGTLEGSKQSQTEPEGARGSKAAFLRQPSGSGRAPSPAAPCLSKASPDL
Sbjct: 661 KPSLPSDPQDRPGTLEGSKQSQTEPEGARGSKAAFLRQPSGSGRAPSPAAPCLSKASPDL 720

Query: 721 PEQWQLWPPVPSGCASLSSQHSYFDTESSSSDEFFCRCHRPYCEICFQSSSDSSDSGTSD 780
           PEQWQLWPPVPSGCASLSSQHSYFDTESSSSDEFFCRCHRPYCEICFQSSSDSSDSGTSD
Sbjct: 721 PEQWQLWPPVPSGCASLSSQHSYFDTESSSSDEFFCRCHRPYCEICFQSSSDSSDSGTSD 780

Query: 781 TDPEPTGGLASWEKLWARSKPIVNFKDDLKPTLV 814
           TDPEPTGGLASWEKLWARSKPIVNFKDDLKPTLV
Sbjct: 781 TDPEPTGGLASWEKLWARSKPIVNFKDDLKPTLV 814


>gi|40255245 G protein-coupled receptor 51 [Homo sapiens]
          Length = 941

 Score =  150 bits (380), Expect = 3e-36
 Identities = 99/348 (28%), Positives = 179/348 (51%), Gaps = 19/348 (5%)

Query: 42  ISSLSPVLLGIVWTFLSCGLLLILFFLAFTIHCRKNRIVKMSSPNLNIVTLLGSCLTYSS 101
           +  +S  L  I+      G+++   FL F I  R  +++KMSSP +N + +LG  L+Y+S
Sbjct: 474 LRKISLPLYSILSALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYAS 533

Query: 102 AYLFGIQDVLVG-SSMETLIQTRLSMLCIGTSLVFGPILGKSWRLYKVFTQRVPDKRVII 160
            +LFG+    V   + ETL   R  +L +G +  FG +  K+WR++ +F + V  K+ II
Sbjct: 534 IFLFGLDGSFVSEKTFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIF-KNVKMKKKII 592

Query: 161 KDLQLLGLVAALLMADVILLMTWVLTDPI-QCLQILSVSMTVTGKDVSCTSTSTHFCASR 219
           KD +LL +V  +L+ D+ +L+ W   DP+ + ++  S+     G+D+S      H C + 
Sbjct: 593 KDQKLLVIVGGMLLIDLCILICWQAVDPLRRTVEKYSMEPDPAGRDISIRPLLEH-CENT 651

Query: 220 YSDVWIALIWGCKGLLLLYGAYLAGLTGHVSSPPVNQSLTIMVGVNLLVLAAGLLFVVTR 279
           +  +W+ +++  KGLL+L+G +LA  T +VS P +N S  I + V  + +   +   V+ 
Sbjct: 652 HMTIWLGIVYAYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAVSF 711

Query: 280 YLHSWPNLVFGLTSGGIFVCTTTINCFIFIPQLKQWKAFEEENQTIRRMAKYFSTPNKSF 339
                PN+ F + +  I  C+T   C +F+P+L   +   +            +T N+ F
Sbjct: 712 LTRDQPNVQFCIVALVIIFCSTITLCLVFVPKLITLRTNPDA-----------ATQNRRF 760

Query: 340 H-TQYGEEENCHPRGEKSSMERLLTEKNAVIESLQEQVNNAKEKIVRL 386
             TQ  ++E+       +S+ +  T +   +E LQ + +  + KI  L
Sbjct: 761 QFTQNQKKEDSKTSTSVTSVNQASTSR---LEGLQSENHRLRMKITEL 805


>gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform c
           precursor [Homo sapiens]
          Length = 899

 Score =  119 bits (297), Expect = 1e-26
 Identities = 100/386 (25%), Positives = 176/386 (45%), Gaps = 14/386 (3%)

Query: 40  KTISSLSPVLLGIVWTFLSCGLLLILFFLAFTIHCRKNRIVKMSSPNLNIVTLLGSCLTY 99
           KT   LS  L   V    S G++L +  L+F I+    R ++ S PNLN +T +G  L  
Sbjct: 520 KTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLAL 579

Query: 100 SSAYLFGIQDVLVGSSMETLI-QTRLSMLCIGTSLVFGPILGKSWRLYKVFTQRVPDK-- 156
           ++ +  G+    +G +    + Q RL +L +G SL +G +  K W ++ VFT++   K  
Sbjct: 580 AAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEW 639

Query: 157 RVIIKDLQLLGLVAALLMADVILLMTWVLTDPI-QCLQILSVSMTVTGKDVSCTSTSTHF 215
           R  ++  +L   V  L+  DV+ L  W + DP+ + ++  +        DVS      H 
Sbjct: 640 RKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEH- 698

Query: 216 CASRYSDVWIALIWGCKGLLLLYGAYLAGLTGHVSSPPVNQSLTIMVGVNLLVLAAGLLF 275
           C+SR  + W+ + +G KGLLLL G +LA  T  VS+  +N    + + +  + +   +  
Sbjct: 699 CSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITA 758

Query: 276 VVTRYLHSWPNLVFGLTSGGIFVCTTTINCFIFIPQLKQWKAFEEENQTIRRMAKYFSTP 335
            VT  L S  +  F   S  I   +      +F+P++++     E     +   K  S+ 
Sbjct: 759 PVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSST 818

Query: 336 NKSFHTQYGEEENCHPRGEKSSMERLLTEKNAVIESLQEQVNNAKEKIVRLMSAECTYDL 395
           N +      EE++     E   +E+++ EK   +  L+ Q+ + ++  +R      T   
Sbjct: 819 NNN-----EEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQ--LRSRRHPPTPPE 871

Query: 396 PEGAAP--PASSPNKDVQAVASVHTL 419
           P G  P  P   P++     + VH L
Sbjct: 872 PSGGLPRGPPEPPDRLSCDGSRVHLL 897


>gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform b
           precursor [Homo sapiens]
          Length = 844

 Score =  119 bits (297), Expect = 1e-26
 Identities = 100/386 (25%), Positives = 176/386 (45%), Gaps = 14/386 (3%)

Query: 40  KTISSLSPVLLGIVWTFLSCGLLLILFFLAFTIHCRKNRIVKMSSPNLNIVTLLGSCLTY 99
           KT   LS  L   V    S G++L +  L+F I+    R ++ S PNLN +T +G  L  
Sbjct: 465 KTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLAL 524

Query: 100 SSAYLFGIQDVLVGSSMETLI-QTRLSMLCIGTSLVFGPILGKSWRLYKVFTQRVPDK-- 156
           ++ +  G+    +G +    + Q RL +L +G SL +G +  K W ++ VFT++   K  
Sbjct: 525 AAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEW 584

Query: 157 RVIIKDLQLLGLVAALLMADVILLMTWVLTDPI-QCLQILSVSMTVTGKDVSCTSTSTHF 215
           R  ++  +L   V  L+  DV+ L  W + DP+ + ++  +        DVS      H 
Sbjct: 585 RKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEH- 643

Query: 216 CASRYSDVWIALIWGCKGLLLLYGAYLAGLTGHVSSPPVNQSLTIMVGVNLLVLAAGLLF 275
           C+SR  + W+ + +G KGLLLL G +LA  T  VS+  +N    + + +  + +   +  
Sbjct: 644 CSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITA 703

Query: 276 VVTRYLHSWPNLVFGLTSGGIFVCTTTINCFIFIPQLKQWKAFEEENQTIRRMAKYFSTP 335
            VT  L S  +  F   S  I   +      +F+P++++     E     +   K  S+ 
Sbjct: 704 PVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSST 763

Query: 336 NKSFHTQYGEEENCHPRGEKSSMERLLTEKNAVIESLQEQVNNAKEKIVRLMSAECTYDL 395
           N +      EE++     E   +E+++ EK   +  L+ Q+ + ++  +R      T   
Sbjct: 764 NNN-----EEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQ--LRSRRHPPTPPE 816

Query: 396 PEGAAP--PASSPNKDVQAVASVHTL 419
           P G  P  P   P++     + VH L
Sbjct: 817 PSGGLPRGPPEPPDRLSCDGSRVHLL 842


>gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform a
           precursor [Homo sapiens]
          Length = 961

 Score =  119 bits (297), Expect = 1e-26
 Identities = 100/386 (25%), Positives = 176/386 (45%), Gaps = 14/386 (3%)

Query: 40  KTISSLSPVLLGIVWTFLSCGLLLILFFLAFTIHCRKNRIVKMSSPNLNIVTLLGSCLTY 99
           KT   LS  L   V    S G++L +  L+F I+    R ++ S PNLN +T +G  L  
Sbjct: 582 KTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLAL 641

Query: 100 SSAYLFGIQDVLVGSSMETLI-QTRLSMLCIGTSLVFGPILGKSWRLYKVFTQRVPDK-- 156
           ++ +  G+    +G +    + Q RL +L +G SL +G +  K W ++ VFT++   K  
Sbjct: 642 AAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEW 701

Query: 157 RVIIKDLQLLGLVAALLMADVILLMTWVLTDPI-QCLQILSVSMTVTGKDVSCTSTSTHF 215
           R  ++  +L   V  L+  DV+ L  W + DP+ + ++  +        DVS      H 
Sbjct: 702 RKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEH- 760

Query: 216 CASRYSDVWIALIWGCKGLLLLYGAYLAGLTGHVSSPPVNQSLTIMVGVNLLVLAAGLLF 275
           C+SR  + W+ + +G KGLLLL G +LA  T  VS+  +N    + + +  + +   +  
Sbjct: 761 CSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITA 820

Query: 276 VVTRYLHSWPNLVFGLTSGGIFVCTTTINCFIFIPQLKQWKAFEEENQTIRRMAKYFSTP 335
            VT  L S  +  F   S  I   +      +F+P++++     E     +   K  S+ 
Sbjct: 821 PVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSST 880

Query: 336 NKSFHTQYGEEENCHPRGEKSSMERLLTEKNAVIESLQEQVNNAKEKIVRLMSAECTYDL 395
           N +      EE++     E   +E+++ EK   +  L+ Q+ + ++  +R      T   
Sbjct: 881 NNN-----EEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQ--LRSRRHPPTPPE 933

Query: 396 PEGAAP--PASSPNKDVQAVASVHTL 419
           P G  P  P   P++     + VH L
Sbjct: 934 PSGGLPRGPPEPPDRLSCDGSRVHLL 959


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 84/328 (25%), Positives = 125/328 (38%), Gaps = 60/328 (18%)

Query: 429  LSDFQNDPGMAARD-SQCTSGPSSYAQSLEGPGKDSSFSPGKEEK--ISDSKDFSDHLDS 485
            L+  + DP +  ++ S  +SG SS           S  SP   EK  +S ++  S  +  
Sbjct: 1360 LNQLETDPSLDMKEQSTRSSGHSS-----------SELSPDAVEKAGMSSNQSISSPVLD 1408

Query: 486  GCSQKPWTEQSLG---PERGDQVPMNPSQSLLPDRGGSDPQRQRHLENSEEPPERRSRVS 542
               + P  E+S     PE  D +P  PS+     R GS P     L +    P R S   
Sbjct: 1409 AVPRTPSRERSSSASSPEMKDGLPRTPSRR---SRSGSSPG----LRDGSGTPSRHSLSG 1461

Query: 543  SVIREKLQEVLQDLGLG-PEASLSTAPSCHQQTWK-----------NSAAFSPQKMPLSK 590
            S     ++++ +    G  E   S  P    QT +           N+   +PQ+     
Sbjct: 1462 S--SPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGS 1519

Query: 591  ELGFSPYMVRRRRAAQRARSHF-------PGSAP-------SSVGHRANRTVPGAHSRLH 636
            E       V R    QR+RS         P ++P       SS   +A    P    R  
Sbjct: 1520 ESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTP---LRQR 1576

Query: 637  VQNGDSPSLAPQTTDSRVRRPSSRKPSLPSDPQDRPGTLEGSKQSQTEPEGARGSKAAFL 696
             ++G SP +  ++  S  R  S   P +   P+  P    GS  S  EP+ A   +A   
Sbjct: 1577 SRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGS-DSSPEPK-APAPRALPR 1634

Query: 697  RQPSGS---GRAPSPAAPCLSKASPDLP 721
            R  SGS   GR PSP     +++SP+ P
Sbjct: 1635 RSRSGSSSKGRGPSPEGSSSTESSPEHP 1662



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 78/372 (20%), Positives = 131/372 (35%), Gaps = 17/372 (4%)

Query: 351  PRGEKSSMERLLTEKNAVIESLQEQVNNAKEKIVRLMSAECTYDLPEGAAPPASSPNKDV 410
            P+ E+S  E  + +K      L ++  +   + + +  +    +  E  + P S      
Sbjct: 1512 PQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSK----- 1566

Query: 411  QAVASVHTLAAAQGPSGHLSDFQNDPGMAARDSQCTSGPSSYAQSLEGPGKDSSFSPGKE 470
               A   T    +  SG   +  +   ++ R S+  S P    +    P   S      E
Sbjct: 1567 ---AKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPE 1623

Query: 471  EKISDSKDFSDHLDSGCSQKPWTEQSLGPERGDQVPMNPSQSLLPDRGG-SDPQRQRHLE 529
             K    +       SG S K       G    +  P +P +S    RG  S P+ +    
Sbjct: 1624 PKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKT--- 1680

Query: 530  NSEEPPERRSRVSS---VIREKLQEVLQDLGLGPEASLSTAPSCHQQTWKNSAAFSPQKM 586
             S  PP RRS  SS     + +L    +     PE    T P  H+++   S+   P + 
Sbjct: 1681 KSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPR-HRRSPSVSSP-EPAEK 1738

Query: 587  PLSKELGFSPYMVRRRRAAQRARSHFPGSAPSSVGHRANRTVPGAHSRLHVQNGDSPSLA 646
              S     S    R +  ++R RS  P           +R      +R   ++G S S +
Sbjct: 1739 SRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTS 1798

Query: 647  PQTTDSRVRRPSSRKPSLPSDPQDRPGTLEGSKQSQTEPEGARGSKAAFLRQPSGSGRAP 706
             +   SR R   +R+    S    R    + S ++ +     R       R+ S S  +P
Sbjct: 1799 RRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSP 1858

Query: 707  SPAAPCLSKASP 718
            +P     S+ASP
Sbjct: 1859 APWKRSRSRASP 1870



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 82/337 (24%), Positives = 122/337 (36%), Gaps = 48/337 (14%)

Query: 397 EGAAPPASSPNKDVQAVASVHTLAAA-------QGPSGHLSDFQNDPGMAARDSQCTSGP 449
           + A+   +S ++   A A  HT A A        G  G      ++PG  +  +Q  S P
Sbjct: 267 DSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTS--TQRPSSP 324

Query: 450 SSYAQSLEGPGKDSSFSPGKEEKISDSKDFSDHLDSGCSQKPWTEQSLGPERG------- 502
            +  +    P +D      K+EK +     S    S   + P     L    G       
Sbjct: 325 ETATKQPSSPYEDKD--KDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLA 382

Query: 503 ----DQVPMNPSQSLLPDRGGSDPQRQRHLENSEEPPERRSRVSSVIREKLQEVLQDLGL 558
                Q P+NP     P R  S P      ++ E+ P+  S  SS    +  +V +    
Sbjct: 383 TTPLSQEPVNPPSEASPTRDRSPP------KSPEKLPQSSSSESSPPSPQPTKVSRHASS 436

Query: 559 GPEA-SLSTAPSCHQQ-----TWKNSAAFSPQKMPLSKELGFSPYMVRRRRAAQRARSHF 612
            PE+   + AP  H++     T KN  +    K   S     S  M R R  A   R   
Sbjct: 437 SPESPKPAPAPGSHREISSSPTSKN-RSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRS 495

Query: 613 PGSAPSSVGHRANRTVPGAHSRLHVQNGDSPSLAPQTTDSRVRRPSSRKPSLPSDPQDRP 672
               P+  GH  +R+     SR   + G S S  PQ      RR  SR P  P   + R 
Sbjct: 496 RSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRS--PQ------RRGRSRSPQRPGWSRSRN 547

Query: 673 GTLEGSKQSQTEPEGARGSKAAFLRQPSGSGRAPSPA 709
               G  +S++   G   S++   R   G  R+ +PA
Sbjct: 548 TQRRG--RSRSARRGRSHSRSPATR---GRSRSRTPA 579



 Score = 37.7 bits (86), Expect = 0.043
 Identities = 63/246 (25%), Positives = 96/246 (39%), Gaps = 31/246 (12%)

Query: 517  RGGSDPQRQRHLENSEEPPERR---SRVSSVIREKLQEVLQDLGLGPEASLSTAPSCHQQ 573
            R  + P  +R   +   P  RR   SR    IR + +   +   L  + S S +P   + 
Sbjct: 1995 RSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRS--RTPLLPRKRSRSRSPLAIR- 2051

Query: 574  TWKNSAAFSPQKMPLSKELGFSPYMVRRRRAA----QRARSHFPGSAPSSVGHRANRTVP 629
              + S + +P+     + L  SP  +RRR A+     R+RS  P   P++  H  +RT P
Sbjct: 2052 --RRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATP---PATRNHSGSRTPP 2106

Query: 630  GAHSRLHVQNGDSPSLAPQTTDSRVRRP-------SSRKP-----SLPSDPQDRPGTLEG 677
             A +   +     PS++P   D R R P       SSR P            D PG    
Sbjct: 2107 VALNSSRMSCFSRPSMSPTPLD-RCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIP 2165

Query: 678  SKQSQTEPEGARGSKAAFLRQPSGSGRA---PSPAAPCLSKASPDLPEQWQLWPPVPSGC 734
              Q  + PE    S+ A        G A   PS +A  L+     +P    L     +  
Sbjct: 2166 DHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPA 2225

Query: 735  ASLSSQ 740
            A+L+S+
Sbjct: 2226 ANLASR 2231



 Score = 37.7 bits (86), Expect = 0.043
 Identities = 54/180 (30%), Positives = 68/180 (37%), Gaps = 21/180 (11%)

Query: 607  RARSHFPGSAPSSVGHRANRTVPGAHSRLHVQNGDSPSLAPQTTDSRVRRPSSRKPSLPS 666
            RARS  P SAPS     + R  P   SR+      S SL P   D    +P S  PS  S
Sbjct: 2404 RARSRTPPSAPSQSRMTSERA-PSPSSRMG--QAPSQSLLPPAQD----QPRSPVPSAFS 2456

Query: 667  DPQDRPGTLEGSKQ--SQTEPEGARGSKAAFLRQPSGSGRAPSPAAPCLSKASPDLPEQW 724
            D Q R    + +    SQ+   GA  +  +     +G    P+P  P      P      
Sbjct: 2457 D-QSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGA 2515

Query: 725  QLWPPVPSGCASLSSQHSYFDTESSSSDEFFCRCHRPYCEICFQSSSDSSDSGTSDTDPE 784
            Q     PS  A+L        + SSSS                 SSS SS SG+S +D E
Sbjct: 2516 QQ----PSALAALQPAKERRSSSSSSSSSSSSSSSS-------SSSSSSSSSGSSSSDSE 2564



 Score = 35.0 bits (79), Expect = 0.28
 Identities = 96/432 (22%), Positives = 152/432 (35%), Gaps = 77/432 (17%)

Query: 336  NKSFHTQYGEEENCHPRGEKSSMERLLTEKNAVIESLQEQVNNAKEKIVRLMSAECTYDL 395
            NKS  +Q     N  P  +KS   R+ + ++  + S + +  + +  + R +S       
Sbjct: 732  NKSRTSQRRSRSNSSPEMKKS---RISSRRSRSLSSPRSKAKS-RLSLRRSLSGSSPCPK 787

Query: 396  PEGAAPPASSPNKDVQAVASVHTLAAAQGPSGHLSDFQNDPGMAARDSQCTSGPSSYAQS 455
             +   PP  S +   Q  A   T       S      Q      +R S  +S P    +S
Sbjct: 788  QKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSK-TPSRQSHSSSSPHPKVKS 846

Query: 456  LEGPGKDSSFSP-GKEEKISD---------------SKDFSDHLDSGCSQKPWTEQSLGP 499
               P + S  SP   E+ ++                S+  S H  SG S  P  + S  P
Sbjct: 847  GTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSG-SSPPRVKSSTPP 905

Query: 500  ERGDQVPMNPSQSLLPD---RGGSDPQRQRHLENSEEPPER--------RSR----VSSV 544
             +      +PS+S  P    +    P+++ H  +S   P R        RSR     S+V
Sbjct: 906  RQ------SPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNV 959

Query: 545  IREKLQEVLQDLGLGPEASLSTAPSCHQQTWKNSAAFSPQ-----KMPLSKELGFSPYMV 599
                L          P+  +       Q    +S + SP      + P    L  S    
Sbjct: 960  ESRLLPRYSHSGSSSPDTKVKPETPPRQS---HSGSISPYPKVKAQTPPGPSLSGSKSPC 1016

Query: 600  RRRRAAQRARSHFPGSAPSSVGHRANRTVPG------AHSRLHVQNGDSPSLAPQTTDSR 653
             + ++        PGS     G +++ T PG      +  +L  Q+  SP     T+   
Sbjct: 1017 PQEKSKDSLVQSCPGSLSLCAGVKSS-TPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPE 1075

Query: 654  VRRPSSRKPSLPSDPQDRPGTLEGSKQSQTEPEGARGSKAAFL-----RQPSGSGRAPSP 708
            VR+  S  PSL S             +SQT P+G R   ++ +     R P    R    
Sbjct: 1076 VRQSHSESPSLQS-------------KSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFS 1122

Query: 709  AAPCL-SKASPD 719
            A+P L S  SP+
Sbjct: 1123 ASPMLKSGMSPE 1134



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 55/266 (20%), Positives = 94/266 (35%), Gaps = 41/266 (15%)

Query: 527 HLENSEEPPERRSRVSSVIREKLQEVLQDLGLGPEASLSTAPSCHQQTWKNSAAFSPQKM 586
           +++ S   P+RR+R +   ++   E  +   L  E+S S +P+  Q+  K       +  
Sbjct: 145 YVDGSSFDPQRRAREA---KQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSE 201

Query: 587 PLSKELGFSPYMVRRRRAAQRARSHFPGSAPSSVGHRANRTVPGAHSRLHVQNGDSPSLA 646
             S          R R+ + + + H   S      HR+                 +P   
Sbjct: 202 SSSPR--------RERKKSSKKKKHRSESESKKRKHRS----------------PTPKSK 237

Query: 647 PQTTDSRVRRPSSRKPSLPSDPQDRPGTLEGSKQSQTEPEGARGSKAAFLRQPSGSGRAP 706
            ++ D + +R  S  P+  S    R  + + +  S T    +R S AA     + +GR+P
Sbjct: 238 RKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSR-SAAAKTHTTALAGRSP 296

Query: 707 SPAAPCLSKASPDLPEQWQLWPPVPSGCASLSSQHS--YFDTESSSSDEFFCRCHRPYCE 764
           SPA+    +      E        PS   + + Q S  Y D +    ++   R       
Sbjct: 297 SPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATR------- 349

Query: 765 ICFQSSSDSSDSGTSDTDPEPTGGLA 790
                S     S T    P PT  LA
Sbjct: 350 ----PSPSPERSSTGPEPPAPTPLLA 371



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 68/265 (25%), Positives = 91/265 (34%), Gaps = 30/265 (11%)

Query: 531  SEEPPERRSRVSSVIREKLQEVLQDLGLGPEASLSTAPSCHQQTWKNSAAFSPQKMPLSK 590
            S  PP   S+ S +  E+       +G  P  SL   P+  Q      +AFS Q   L  
Sbjct: 2407 SRTPPSAPSQ-SRMTSERAPSPSSRMGQAPSQSL-LPPAQDQPRSPVPSAFSDQSRCLIA 2464

Query: 591  ELGFSPYMVRRRRAAQRARSHFPGSAPSSVG-HRANRTVPGA---HSRLHVQ----NGDS 642
            +   +P        +Q   S    +  SS G H    +VP     HS +           
Sbjct: 2465 QT--TPVA-----GSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQ 2517

Query: 643  PSLAPQTTDSRVRRPSSRKPSLPSDPQDRPGTLEGSKQSQTEPEGARGSKAAFLRQPSGS 702
            PS       ++ RR SS   S  S       +   S  S +    + GS      QP  +
Sbjct: 2518 PSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPV--QPEVA 2575

Query: 703  -GRAPSPA-APCLSKASPDLPEQWQLWPPVPSGCASLSSQHSYFDTESSSSDEFFCRCHR 760
              R PSP  AP  +      PE         S  +S SS  S   + SSSS         
Sbjct: 2576 LKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSS------- 2628

Query: 761  PYCEICFQSSSDSSDSGTSDTDPEP 785
                    SSS SS S +S + P P
Sbjct: 2629 --SSSSSSSSSSSSSSSSSSSSPSP 2651


>gi|50083281 KIAA1853 protein [Homo sapiens]
          Length = 611

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 82/351 (23%), Positives = 133/351 (37%), Gaps = 24/351 (6%)

Query: 456 LEGPGKDSSFSPGKEEKISDSKDFSDHLDSG--CSQKPWTEQSLGPERGDQVPMNPSQSL 513
           + G G  +         ++ S+  S   DSG   S  P T+ S    RG Q   +PS   
Sbjct: 258 ITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRG-QEKGSPS--- 313

Query: 514 LPDRGGSDPQRQRHLENSEEPPERRSRVSSVIREKLQEVLQDLGLGPEASLSTAPSCH-Q 572
               GG    R+ +  N+ +     +  S   +  + E L     G E+    +P     
Sbjct: 314 ----GGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECA 369

Query: 573 QTWKNSAAFSPQKMPLSKELGFSPYMVRRRRAAQRARSHFPGSAPSSVGHRANRTVPGAH 632
           +  K+S   S  +    K    S      R ++  +RS  P ++P     R+  +   ++
Sbjct: 370 EVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSY 429

Query: 633 SRLHVQNGDSPSLAPQTTDSRVRRPSSRKPSLPSDPQDRPGTLEGSKQSQTEPEGARGSK 692
           SR    +  S   +P +  SR RR  S     PS  +D P   E   Q Q E E AR  +
Sbjct: 430 SRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERD-PKYSEKDSQ-QRERERARRRR 487

Query: 693 AAFLRQPSGSGRAPSPAAPCLSKASPDLPEQWQLWPPVPSGCASLSSQHSYFDTESSSSD 752
            ++   P    R  SP+     + +         + P PS   SLSS  S++ + SS S 
Sbjct: 488 RSY--SPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRS- 544

Query: 753 EFFCRCHRPYCEICFQSSS---DSSDSGTSDTDPEPTGGLASWEKLWARSK 800
                  R Y     +S S     + + +S +   P+ G  S  +  +RS+
Sbjct: 545 -----ASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSR 590


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 61/240 (25%), Positives = 90/240 (37%), Gaps = 51/240 (21%)

Query: 515 PDRGGSDPQRQRHLENSEEPPERRSRVSSVI----REKLQEVLQDLGLGPEASLSTAP-- 568
           P R  S P++ R L  S  PP RR R S       + +     Q      ++ +S +P  
Sbjct: 375 PKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGR 434

Query: 569 -----SCHQQTWKN---SAAFSPQKMPLSKE---------LGFSPYMVRRRRAAQRARSH 611
                + H+ T K    S A  P+K+ LS+             S    R+ R   +  S 
Sbjct: 435 TSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSS 494

Query: 612 FPGSAPSSVGHRANRTVPGAHSRLHVQNGDSPSLAPQTTDSRVRRPSSRKPSLPSDPQDR 671
             GS+ SS   R  R+        HV+NG+            V R     PS  + P  R
Sbjct: 495 DSGSSSSSEDERPKRS--------HVKNGE------------VGRRRRHSPSRSASPSPR 534

Query: 672 PGTLEGSKQSQTEPEGARGSKAAFLRQPSGSGRAPSPAAPCLSKASPDLPEQWQLWPPVP 731
                  +Q +T P G R    +    P+   R+PSPA P   + +P  P + +   P P
Sbjct: 535 ------KRQKETSPRGRRRRSPS--PPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPP 586



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 82/331 (24%), Positives = 115/331 (34%), Gaps = 26/331 (7%)

Query: 441 RDSQCTSGPSSYAQSLEG------PGKDSSFSPGKEEKISDSKD--FSDHLDSG-CSQKP 491
           R S   SG SS + S         P K +S  P K  ++S S       H  S   +  P
Sbjct: 350 RSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPP 409

Query: 492 WTEQSLGPERGDQVPMNPSQSLLPDRGGSDPQRQRHLENSEEP-PERRSRVSSVIREKLQ 550
            T  S  P++ ++   +   S+ P R      + +  E  E P P  + R     + +L 
Sbjct: 410 KTRHSPTPQQSNRTRKS-RVSVSPGRTSGKVTKHKGTEKRESPSPAPKPR-----KVELS 463

Query: 551 EVLQDLGLGPEASLSTAPSCHQQTWKNSAAFSPQKMPLSKELGFSPYMVRRRRAAQRARS 610
           E  +D G G  A+  +     Q   +N  + S      S E         +     R R 
Sbjct: 464 ESEEDKG-GKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRR 522

Query: 611 HFPG-SAPSSVGHRANRTVPGAHSRLH-----VQNGDSPSLAPQTTDSRVRRPSSRKPSL 664
           H P  SA  S   R   T P    R        +   SPS AP     R   P  R+ + 
Sbjct: 523 HSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRT- 581

Query: 665 PSDPQDR--PGTLEGSKQSQTEPEGARGSKAAFLRQPSGSGRAPSPAAPCLSKASPDLPE 722
           PS P  R  P     S   Q     +   K      P    R  SP+ P   + S   P 
Sbjct: 582 PSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPP 641

Query: 723 QWQLWPPVPSGCASLSSQHSYFDTESSSSDE 753
           + +  P       SLSS+H    + S S+ E
Sbjct: 642 KQRSSPVTKRRSPSLSSKHRKGSSPSRSTRE 672



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 47/203 (23%), Positives = 67/203 (33%), Gaps = 14/203 (6%)

Query: 517 RGGSDPQRQRHLENSEEPPERRSRVSSVIREKLQEVLQDLGLGPEASLSTAPSCHQQTWK 576
           R    P  +R   +   PP+RR+  S   + ++             +   +PS   +  K
Sbjct: 603 RYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRK 662

Query: 577 NSAAFSPQKMPLSKELGFSPYMVRRRRAAQRARSHFPGSAPSSVGHRANRTVPGAHSRLH 636
            S   SP +   S     SP   +R   + R R+    S+P  V         GA S   
Sbjct: 663 GS---SPSR---STREARSPQPNKRHSPSPRPRAPQTSSSPPPVRR-------GASSSPQ 709

Query: 637 VQNGDSPSLAPQTTDSRVRRPSS-RKPSLPSDPQDRPGTLEGSKQSQTEPEGARGSKAAF 695
            +   SPS  P    SR   P   +K + PS    R  +   S     EP   +      
Sbjct: 710 RRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPS 769

Query: 696 LRQPSGSGRAPSPAAPCLSKASP 718
             Q        SPA P     SP
Sbjct: 770 PVQSQSPSTNWSPAVPVKKAKSP 792


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 74/286 (25%), Positives = 103/286 (36%), Gaps = 50/286 (17%)

Query: 457 EGPGK-------DSSFSPGKEEKISDSKDFS----DHLDSGCSQKPWTEQSLGPERGDQV 505
           E PG+        SS SP      SDS+  S     H D G  +K  +++S G       
Sbjct: 246 ESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEG--RKTGSQRSSGSRSPS-- 301

Query: 506 PMNPSQSLLPDRGGSDPQRQR----HLENSEEPPERRSRVSSVIREKLQEVLQDLGLGPE 561
           P   S    P R G   QR         ++  PP++ S  S  +R+K             
Sbjct: 302 PSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAA----------- 350

Query: 562 ASLSTAPSCHQQTWKNSAAFSPQKMPLSKELG---FSPYMVRRRRAAQRARSHFPGSAPS 618
           A+  T P+      +   + SP+  P S+  G         RRRR  +R RS    SAP 
Sbjct: 351 AAAPTPPA------RGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPR 404

Query: 619 SVGHRANRTVPGAHSRLHVQNGDSPSLAPQTTDSRVRRPSSRKPSLPSDPQDRPGTLEGS 678
             G R  R  P   S        S S A  ++DS   R +   P    +P    G     
Sbjct: 405 RRGRRRPRPAPPRGS------SRSLSRARSSSDSGSGRGA---PGPGPEPGSERGHGGHG 455

Query: 679 KQSQTEPEGARGSKAAFLRQPSGSGRAPSPAAPCLSKASPDLPEQW 724
           K+++  P  AR   A+    P   GR   P     S++    P  W
Sbjct: 456 KRAKERPPRAR--PASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSW 499



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 53/227 (23%), Positives = 83/227 (36%), Gaps = 33/227 (14%)

Query: 423 QGPSGHLSDFQNDPGMAARDSQCTSGPSSYAQSLEGPGKDSSFSPGKEEKISDSKDFSDH 482
           +G  GH    +  P  A R +  +  P ++ +     GK SS SPG   +   S      
Sbjct: 449 RGHGGHGKRAKERPPRA-RPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSS------ 501

Query: 483 LDSGCSQKPWTEQSLGPERGDQVPM---NPSQSLLPDRGGSDPQRQRHLENSEEPPERRS 539
                S+ P   +S   E+    P    +P + L  D+ G    R RH E       RRS
Sbjct: 502 -----SRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEG--RARHSEAEATRARRRS 554

Query: 540 RVSSVIREKLQEVLQDLGLGPEASLSTAPSCHQQTWKNSAA------FSPQKMPLSKELG 593
           R  S IR++ ++    +      S    P  + +   +S++      +S +    S   G
Sbjct: 555 RSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPG 614

Query: 594 FSPYMVRRRRAAQRARSHFPGSAPSSVGHRANRTVPGAHSRLHVQNG 640
            S      R    R+R+  P   PS          P  HSR   ++G
Sbjct: 615 HSHGSYSSRSHGTRSRTRSPSRTPS----------PSYHSRSSSESG 651


>gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens]
          Length = 912

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 35/144 (24%), Positives = 62/144 (43%), Gaps = 14/144 (9%)

Query: 47  PVLLGIVWTFLSCGLLLILFFLAFTIHCRKNRIVKMSSPNLNIVTLLGSCLTYSSAYLFG 106
           P+ L +V      G+   LF +   +      IVK S   L+ V L G  L Y++ +L  
Sbjct: 591 PLFLAVV------GIAATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMI 644

Query: 107 IQDVLVGSSMETLIQTRLSMLCIGTSLVFGPILGKSWRLYKVFTQ--RVPDKRVIIKDLQ 164
            +  L   S+  +       L +G S+ +  +L K+ R+Y++F Q  R       I    
Sbjct: 645 AEPDLGTCSLRRIF------LGLGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPAS 698

Query: 165 LLGLVAALLMADVILLMTWVLTDP 188
            L +  +L+   ++ +  W + DP
Sbjct: 699 QLAITFSLISLQLLGICVWFVVDP 722


>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
          Length = 1163

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 59/273 (21%), Positives = 93/273 (34%), Gaps = 17/273 (6%)

Query: 461 KDSSFSPGKEEKISDSKDFSDHLDSGCSQKPWTEQSLGPERGDQVPMNPSQ-----SLLP 515
           K +S S  K  +I ++   S   D   S  P ++    PE  ++ P+ PS      S   
Sbjct: 631 KSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPE-SNRTPVKPSSVEEEDSFFR 689

Query: 516 DRGGSDPQRQRHLENSEEPPERRSRVSSVIREKLQEVL---QDLGLGPEASLSTAPSCHQ 572
            R  S  + +  L    EP +R   +  +    L  +          P+      P  H 
Sbjct: 690 QRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHT 749

Query: 573 QTWKNSAAFSPQKMPLSKELGFSPYMVRRRRAAQRARSHFPGSAPSSVGHRANRTVPGAH 632
           +  +  A+         K            +  +    +  G  PSS    + ++     
Sbjct: 750 REAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEK 809

Query: 633 SRLHVQNGDSPSLAPQTTDSRVRRPSSRKPSLPSDPQDRPGT-------LEGSKQSQTEP 685
             L    G  PS  P+T     +R  S+  SL S       T          SKQ +TE 
Sbjct: 810 DLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEG 869

Query: 686 EGARGSKAAFLRQPSGSGRAPSPAAPCLSKASP 718
           + +  SK    + PS S   P P+AP L  + P
Sbjct: 870 KTSSSSKEVKEKAPSSSSNCP-PSAPTLDSSKP 901


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 57/217 (26%), Positives = 77/217 (35%), Gaps = 25/217 (11%)

Query: 500 ERGDQVPMNPSQSLLPDRGGSDPQRQRHLENSEEPPERRSRVSSVIREKLQEVLQDLGLG 559
           ERG++   N   S  P R   +    +  E  ++  E     S++ RE+  +  Q L   
Sbjct: 387 ERGERRKPNAGGSPAPVRRRPEASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPAS 446

Query: 560 PEASLSTAPSCHQQTWKNSAAFSPQKMPLSKELGFSPYMVRRRRAAQRARSHFPGSA--P 617
           P A L             SA+ + +  P SK    SP      R A    S  PG    P
Sbjct: 447 PRARL-------------SASTASELSPKSKARPSSP-STSWHRPASPCPSPGPGHTLPP 492

Query: 618 SSVGHRANRTVPGAHSRLHVQNGDSPSLA-PQTTDSRVRRPSSRKPS-LPSDPQDRPGTL 675
                R     P    R   +  +SPS A P+      RR S+ K S  P+ P   P   
Sbjct: 493 KPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPS 552

Query: 676 EGSKQSQTE-PEGARGSKAAFLRQPSGSGRAPSPAAP 711
                 Q E P     + AA L  P      P+PA P
Sbjct: 553 PTPAPPQKEQPPAETPTDAAVLTSP------PAPAPP 583


>gi|110611176 glutamate receptor, metabotropic 6 precursor [Homo
           sapiens]
          Length = 877

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 42/180 (23%), Positives = 76/180 (42%), Gaps = 16/180 (8%)

Query: 11  CDSFPGQELDRRPLHDLCKTTITSSHHSSKTISSLSPVLLGIVWTFLSCGLLLILFFLAF 70
           C++ PG ++   P H  C+ T       S   ++  P+LL ++      G++     +A 
Sbjct: 555 CEACPG-DMRPTPNHTGCRPTPVVRLSWSSPWAA-PPLLLAVL------GIVATTTVVAT 606

Query: 71  TIHCRKNRIVKMSSPNLNIVTLLGSCLTYSSAYLFGIQDVLVGSSMETLIQTRLSMLCIG 130
            +      IV+ S   L+ V L G  L Y+  +L      +V      +   R   L +G
Sbjct: 607 FVRYNNTPIVRASGRELSYVLLTGIFLIYAITFL------MVAEPGAAVCAARRLFLGLG 660

Query: 131 TSLVFGPILGKSWRLYKVFTQ--RVPDKRVIIKDLQLLGLVAALLMADVILLMTWVLTDP 188
           T+L +  +L K+ R+Y++F Q  R       I     L +  +L    V+ ++ W+   P
Sbjct: 661 TTLSYSALLTKTNRIYRIFEQGKRSVTPPPFISPTSQLVITFSLTSLQVVGMIAWLGARP 720


>gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4
           [Homo sapiens]
          Length = 818

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 50/213 (23%), Positives = 78/213 (36%), Gaps = 34/213 (15%)

Query: 493 TEQSLGPERGDQVPMNPSQSLLPDRGGSDPQRQRHLENSEEPPERRSRVSSVIREKLQEV 552
           T QSL       VPMNPSQ  L    G +PQ+Q    +S  P  + S   ++  E   + 
Sbjct: 131 TRQSLLGPPPVGVPMNPSQFNL---SGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDP 187

Query: 553 LQDLGLGPEASLSTA-----PSCHQQTWKNSAAFSPQKMPLSKELGFSPYMVRRRRAAQR 607
            +      E  + T      P C +   K     +P+  P       S    +R R+++ 
Sbjct: 188 PEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEA----SELPAKRLRSSEE 243

Query: 608 -ARSHFPGSAPSSVGHRANRTVPGAHSRLHVQNGDSPSLAPQTTDSRV------------ 654
                 PG        +A  TVP        +   +P L P+  +++V            
Sbjct: 244 PTEKEPPGQLQVKAQPQARMTVP--------KQTQTPDLLPEALEAQVLPRFQPRVLQVQ 295

Query: 655 -RRPSSRKPSLPSDPQDRPGTLEGSKQSQTEPE 686
            +  S  +P +PS        L+   Q+QT PE
Sbjct: 296 AQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 328


>gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1
           [Homo sapiens]
          Length = 898

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 50/213 (23%), Positives = 78/213 (36%), Gaps = 34/213 (15%)

Query: 493 TEQSLGPERGDQVPMNPSQSLLPDRGGSDPQRQRHLENSEEPPERRSRVSSVIREKLQEV 552
           T QSL       VPMNPSQ  L    G +PQ+Q    +S  P  + S   ++  E   + 
Sbjct: 155 TRQSLLGPPPVGVPMNPSQFNL---SGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDP 211

Query: 553 LQDLGLGPEASLSTA-----PSCHQQTWKNSAAFSPQKMPLSKELGFSPYMVRRRRAAQR 607
            +      E  + T      P C +   K     +P+  P       S    +R R+++ 
Sbjct: 212 PEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEA----SELPAKRLRSSEE 267

Query: 608 -ARSHFPGSAPSSVGHRANRTVPGAHSRLHVQNGDSPSLAPQTTDSRV------------ 654
                 PG        +A  TVP        +   +P L P+  +++V            
Sbjct: 268 PTEKEPPGQLQVKAQPQARMTVP--------KQTQTPDLLPEALEAQVLPRFQPRVLQVQ 319

Query: 655 -RRPSSRKPSLPSDPQDRPGTLEGSKQSQTEPE 686
            +  S  +P +PS        L+   Q+QT PE
Sbjct: 320 AQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 352


>gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2
           [Homo sapiens]
          Length = 842

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 50/213 (23%), Positives = 78/213 (36%), Gaps = 34/213 (15%)

Query: 493 TEQSLGPERGDQVPMNPSQSLLPDRGGSDPQRQRHLENSEEPPERRSRVSSVIREKLQEV 552
           T QSL       VPMNPSQ  L    G +PQ+Q    +S  P  + S   ++  E   + 
Sbjct: 155 TRQSLLGPPPVGVPMNPSQFNL---SGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDP 211

Query: 553 LQDLGLGPEASLSTA-----PSCHQQTWKNSAAFSPQKMPLSKELGFSPYMVRRRRAAQR 607
            +      E  + T      P C +   K     +P+  P       S    +R R+++ 
Sbjct: 212 PEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEA----SELPAKRLRSSEE 267

Query: 608 -ARSHFPGSAPSSVGHRANRTVPGAHSRLHVQNGDSPSLAPQTTDSRV------------ 654
                 PG        +A  TVP        +   +P L P+  +++V            
Sbjct: 268 PTEKEPPGQLQVKAQPQARMTVP--------KQTQTPDLLPEALEAQVLPRFQPRVLQVQ 319

Query: 655 -RRPSSRKPSLPSDPQDRPGTLEGSKQSQTEPE 686
            +  S  +P +PS        L+   Q+QT PE
Sbjct: 320 AQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 352


>gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1
           [Homo sapiens]
          Length = 898

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 50/213 (23%), Positives = 78/213 (36%), Gaps = 34/213 (15%)

Query: 493 TEQSLGPERGDQVPMNPSQSLLPDRGGSDPQRQRHLENSEEPPERRSRVSSVIREKLQEV 552
           T QSL       VPMNPSQ  L    G +PQ+Q    +S  P  + S   ++  E   + 
Sbjct: 155 TRQSLLGPPPVGVPMNPSQFNL---SGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDP 211

Query: 553 LQDLGLGPEASLSTA-----PSCHQQTWKNSAAFSPQKMPLSKELGFSPYMVRRRRAAQR 607
            +      E  + T      P C +   K     +P+  P       S    +R R+++ 
Sbjct: 212 PEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEA----SELPAKRLRSSEE 267

Query: 608 -ARSHFPGSAPSSVGHRANRTVPGAHSRLHVQNGDSPSLAPQTTDSRV------------ 654
                 PG        +A  TVP        +   +P L P+  +++V            
Sbjct: 268 PTEKEPPGQLQVKAQPQARMTVP--------KQTQTPDLLPEALEAQVLPRFQPRVLQVQ 319

Query: 655 -RRPSSRKPSLPSDPQDRPGTLEGSKQSQTEPE 686
            +  S  +P +PS        L+   Q+QT PE
Sbjct: 320 AQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 352


>gi|238908524 hypothetical protein LOC389333 [Homo sapiens]
          Length = 1015

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 35/120 (29%), Positives = 43/120 (35%), Gaps = 5/120 (4%)

Query: 600 RRRRAAQRARSHFPGSAPSSVGHRANRTVPGAHSRLHVQNGD-SPSLAPQTTDSRVRRPS 658
           RR     R R+  PG     V   A R VP    R     G  S S       + VR P 
Sbjct: 743 RRPEVTSRVRARGPGGENRDV--EAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPR 800

Query: 659 SRKPSLPSDPQDRPGTLEGSKQSQTEPEGARGSKAAFLRQPSGSGRAPSPAAPCLSKASP 718
              P + + P   PG     K   T PE A   +A   R+P       +PA P  + A P
Sbjct: 801 PGSPQMQASPS--PGIAPKPKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPP 858


>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
          Length = 2303

 Score = 39.7 bits (91), Expect = 0.011
 Identities = 38/122 (31%), Positives = 53/122 (43%), Gaps = 18/122 (14%)

Query: 613  PGSAPSSVGHRANRTVPGAHSRLHVQNGDSPSLAPQTTDSRVRRPSSRKPSLPSDPQDRP 672
            P +AP+   HR    +P A +R   Q G   + AP         P+  +PSL +D     
Sbjct: 1519 PAAAPTPT-HRRTSAIPRAFTRERPQ-GRKEAPAPSKAAPAAPPPARTQPSLIADETPPC 1576

Query: 673  GTLEGSKQSQTEPEGA-------RGSKAAFLRQPS-GSGR--APSPAAP------CLSKA 716
             +L  S  S +EPE +       RG + A  + P  G GR  +PSP A       C+S A
Sbjct: 1577 YSLSSSASSLSEPEPSEPPAVHPRGREPAVTKDPGPGGGRDSSPSPRAAEELLQRCISSA 1636

Query: 717  SP 718
             P
Sbjct: 1637 LP 1638


>gi|32528268 glutamate receptor, metabotropic 7 isoform b precursor
           [Homo sapiens]
          Length = 922

 Score = 39.3 bits (90), Expect = 0.015
 Identities = 32/132 (24%), Positives = 58/132 (43%), Gaps = 10/132 (7%)

Query: 60  GLLLILFFLAFTIHCRKNRIVKMSSPNLNIVTLLGSCLTYSSAYLFGIQDVLVGSSMETL 119
           G++  +F +A  I      IV+ S   L+ V L G  L Y   +L      ++      +
Sbjct: 601 GIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFL------MIAKPDVAV 654

Query: 120 IQTRLSMLCIGTSLVFGPILGKSWRLYKVFTQ---RVPDKRVIIKDLQLLGLVAALLMAD 176
              R   L +G  + +  +L K+ R+Y++F Q    V   R+I    Q L + ++L+   
Sbjct: 655 CSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQ-LAITSSLISVQ 713

Query: 177 VILLMTWVLTDP 188
           ++ +  W   DP
Sbjct: 714 LLGVFIWFGVDP 725


>gi|4504147 glutamate receptor, metabotropic 7 isoform a precursor
           [Homo sapiens]
          Length = 915

 Score = 39.3 bits (90), Expect = 0.015
 Identities = 32/132 (24%), Positives = 58/132 (43%), Gaps = 10/132 (7%)

Query: 60  GLLLILFFLAFTIHCRKNRIVKMSSPNLNIVTLLGSCLTYSSAYLFGIQDVLVGSSMETL 119
           G++  +F +A  I      IV+ S   L+ V L G  L Y   +L      ++      +
Sbjct: 601 GIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFL------MIAKPDVAV 654

Query: 120 IQTRLSMLCIGTSLVFGPILGKSWRLYKVFTQ---RVPDKRVIIKDLQLLGLVAALLMAD 176
              R   L +G  + +  +L K+ R+Y++F Q    V   R+I    Q L + ++L+   
Sbjct: 655 CSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQ-LAITSSLISVQ 713

Query: 177 VILLMTWVLTDP 188
           ++ +  W   DP
Sbjct: 714 LLGVFIWFGVDP 725


>gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3
           [Homo sapiens]
          Length = 837

 Score = 38.5 bits (88), Expect = 0.025
 Identities = 52/210 (24%), Positives = 77/210 (36%), Gaps = 33/210 (15%)

Query: 493 TEQSLGPERGDQVPMNPSQSLLPDRGGSDPQRQRHLENSEEPPERRSRVS--SVIREKLQ 550
           T QSL       VPMNPSQ  L    G +PQ+Q    +S  P  +   V   S   E  +
Sbjct: 155 TRQSLLGPPPVGVPMNPSQFNL---SGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSE 211

Query: 551 EVLQDLGLGPEASLSTAPSCHQQTWKNSAAFSPQKMPLSKELGFSPYMVRRRRAAQR-AR 609
           E  +     PE      P C +   K     +P+  P       S    +R R+++    
Sbjct: 212 EAAEPRMDTPEDQ--DLPPCPEDIAKEKRTPAPEPEPCEA----SELPAKRLRSSEEPTE 265

Query: 610 SHFPGSAPSSVGHRANRTVPGAHSRLHVQNGDSPSLAPQTTDSRV-------------RR 656
              PG        +A  TVP        +   +P L P+  +++V             + 
Sbjct: 266 KEPPGQLQVKAQPQARMTVP--------KQTQTPDLLPEALEAQVLPRFQPRVLQVQAQV 317

Query: 657 PSSRKPSLPSDPQDRPGTLEGSKQSQTEPE 686
            S  +P +PS        L+   Q+QT PE
Sbjct: 318 QSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 347


>gi|151101459 SAPS domain family, member 1 [Homo sapiens]
          Length = 881

 Score = 38.5 bits (88), Expect = 0.025
 Identities = 37/114 (32%), Positives = 50/114 (43%), Gaps = 13/114 (11%)

Query: 607 RARSHFPGSAPSSVGHRANRTVPGAHSRLHVQNGDSPSL------APQTTDSRVRRPSSR 660
           R++   P SAP      +  T P A  +  V  GD  +       AP ++DS  R PS+ 
Sbjct: 769 RSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTS 828

Query: 661 KPSLPSDPQDRPGTLEGSKQSQTEPEGARGSKA--AFLRQPSGSGRAP-SPAAP 711
            P+  S     P T EG K    EP G   S++  A    P  +G AP  PA+P
Sbjct: 829 VPA--SGAHQPPQTTEGEK--SPEPLGLPQSQSAQALTPPPIPNGSAPEGPASP 878


>gi|116268127 kinase non-catalytic C-lobe domain (KIND) containing 1
           isoform a [Homo sapiens]
          Length = 1749

 Score = 38.5 bits (88), Expect = 0.025
 Identities = 58/226 (25%), Positives = 91/226 (40%), Gaps = 47/226 (20%)

Query: 491 PWTEQSLGPERGDQVPMNPSQSLL--PDRGGSDPQRQ----------RHLENSEEPPERR 538
           P +E S GP        +P+++LL  P R G    R+          R L   +    RR
Sbjct: 246 PESETSRGPRA------SPTKALLSTPVRNGESHSREGLAGLVLDAERTLGELDRDALRR 299

Query: 539 SRVSSVIREKLQEVLQDLGLGPEASLSTAPSCHQQTWKNSAAFSP--QKMPLSKELGFSP 596
           SR+  V  +    +L D    PEA+L    +  +     S  FSP  +K  L ++ G S 
Sbjct: 300 SRLRKV--QTFPRLLSD---SPEATLCLPLTRGKSQLPISELFSPDPRKAFLDRKNGLSS 354

Query: 597 YMVRR--RRAAQRARSHFPGSAPSSVGHRANRT--VPGAHSRLHVQNGDSPSLAPQTTDS 652
           +  +   R   ++   H  G  P + G   +R   VPG+  +            P+T+  
Sbjct: 355 FQAQPKCRLWPEQEPEHQLGRVPCA-GRSTDRGPGVPGSPGQ------------PETS-- 399

Query: 653 RVRRPSSRKPSLPSDPQDRPGTLEGSKQSQTEPEGARGSKAAFLRQ 698
               PS      P+DP+D  G  +  +  +  PEGAR  ++A   Q
Sbjct: 400 ---HPSQGPAEAPADPRDASGEAQTPRDDERIPEGARQLESAAAEQ 442


>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 2 [Homo sapiens]
          Length = 1320

 Score = 38.1 bits (87), Expect = 0.033
 Identities = 117/522 (22%), Positives = 180/522 (34%), Gaps = 112/522 (21%)

Query: 321 ENQTIRRMAKYFSTPNKSFHTQYGEEENCHPRGEKSSMERLLTEKNAVIESLQEQV---- 376
           E +  RR+ +      +    +  EEE      E+  + R L E+   +E LQ+Q+    
Sbjct: 431 EQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQ 490

Query: 377 -------------NNAKEKIVRLMSAECTYDL----------PEGAAPPASSPNKDVQAV 413
                        +   E++ R +  E  Y L          P+ +  P   P +  ++ 
Sbjct: 491 AMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPP--PPQQERSK 548

Query: 414 ASVHTLAAAQGPSGHLSDFQNDPGMAARDSQC----TSGPSSYAQSLEGPGKDSSFSPGK 469
            S H    A  P  H      +P   AR+ +     T+  S  AQS +         P +
Sbjct: 549 PSFH----APEPKAHY-----EPADRAREVEDRFRKTNHSSPEAQSKQTGRVLEPPVPSR 599

Query: 470 EEKISDSKDFSDHLDSGCSQKPWTEQS-LGPERGDQVPMNPSQSLLPDRGGSDPQRQ--- 525
            E  S+    S H       +P  + S L   + +  P++ S S       SDP  +   
Sbjct: 600 SESFSNGNSESVHPALQRPAEPQVQWSHLASLKNNVSPVSRSHSF------SDPSPKFAH 653

Query: 526 RHLENSEEPPERRSRVSSVIREKLQEVLQDLGLGPEASLSTAPSCHQQTWKNSAAFS-PQ 584
            HL + +  P  RS V S   +               S S AP   Q+ W  S +   P 
Sbjct: 654 HHLRSQDPCPPSRSEVLSQSSD---------------SKSEAPDPTQKAWSRSDSDEVPP 698

Query: 585 KMPLSKELGFSPYMVRRRRAAQRARSHFPGSAPSSVGHRANRTVPGAHSRLHVQNGDSPS 644
           ++P+ +    SP + RR    Q +     G   S  G R N T           +   P 
Sbjct: 699 RVPV-RTTSRSPVLSRRDSPLQGS-----GQQNSQAGQR-NST-----------SSIEPR 740

Query: 645 LAPQTTDSRVRRPSSRKPSLPSDPQDRPGTLEGSKQSQTEPEGARGSKAAFLRQPSGSGR 704
           L  +  +  V RP S   S  S+   +PG+  GS+    E    R S        S S  
Sbjct: 741 LLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSS--------SKSEG 792

Query: 705 APSPAAPCLSKASPDLPEQWQLWPPVPSGCASLSS-------------QHSYFDTESSSS 751
           +PS       K   D  E ++  P  P+G   L++              H   D  SSS 
Sbjct: 793 SPSQRLENAVKKPEDKKEVFR--PLKPAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSE 850

Query: 752 DEFFCRCHRPYCEICFQSSSDSSDSGTSDTDPEPTGGLASWE 793
           +           E   Q  +D S SG  DT    +  L++ E
Sbjct: 851 ESGTTDEEDDDVE---QEGADESTSGPEDTRAASSLNLSNGE 889


>gi|189011568 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 37.7 bits (86), Expect = 0.043
 Identities = 84/385 (21%), Positives = 139/385 (36%), Gaps = 74/385 (19%)

Query: 344  GEEENCHPRGEKSSMERLLTEKNAVIESLQEQVNNAKEKIVRLMSAECTYDLP--EGAAP 401
            G+     PRG K S++  L+     +     Q+  + +   R  S + T   P  +  + 
Sbjct: 2264 GQTATTSPRGAKPSVKSELSP----VARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSR 2319

Query: 402  PASSPNKDVQAVASVHTLAAAQGPSGHLSDFQNDPGMAARDSQCTSGPSSYAQSLEGPGK 461
            P  SP ++     S+        P   LS               TS PS+ +    G GK
Sbjct: 2320 PIQSPGRN-----SISPGRNGISPPNKLSQLPR-----------TSSPSTASTKSSGSGK 2363

Query: 462  DSSFSPGKE-------EKISDSKDFSDHLDSGCSQKPWTEQSLGPERGDQVPMNPSQSLL 514
             S  SPG++       ++   SK+ S    S  + K   + + G     +V ++   S  
Sbjct: 2364 MSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTK 2423

Query: 515  PDRGGSD-------------------PQRQRHLENSE--EPPERRSRVSSVIREKLQEVL 553
                 SD                   P  +R LE S   E     SR +S  R + Q  +
Sbjct: 2424 SSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPV 2483

Query: 554  QDLGLGPEASLSTAPSCHQQTWKNSAAFSPQKMP--LSKELGFSPYMVRRRRAAQRARSH 611
                L P+ SLST  S     W+        K+P  LS  + ++     +R    R+ S 
Sbjct: 2484 LSPSL-PDMSLSTHSSVQAGGWR--------KLPPNLSPTIEYNDGRPAKRHDIARSHSE 2534

Query: 612  FPGSAPSSVGHRANRTVPGAHSRLHVQNGDS-PSLA----PQTTDSRVRRPSSRKPSLPS 666
             P   P       NR+  G   R H ++  S P ++      ++ S +   S       S
Sbjct: 2535 SPSRLP------INRS--GTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKS 2586

Query: 667  DPQDRPGTLEGSKQSQTEPEGARGS 691
            + +    ++ G+KQS+     A+G+
Sbjct: 2587 EDEKHVNSISGTKQSKENQVSAKGT 2611



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 9/95 (9%)

Query: 657  PSSRKPSLPSDPQDRPGTLEGSKQSQTEPEGARGSKAAFLRQPSGSGRAPSPAAPCLSKA 716
            P S  P++   P+ +   L+GS  S    E AR     F    S   ++PS +     K+
Sbjct: 1319 PVSEVPAVSQHPRTKSSRLQGSSLSS---ESARHKAVEF----SSGAKSPSKSGAQTPKS 1371

Query: 717  SPDLPEQWQLWPPVPSGCASLSSQHSYFDTESSSS 751
             P+     Q  P + S C S+SS  S+     +SS
Sbjct: 1372 PPE--HYVQETPLMFSRCTSVSSLDSFESRSIASS 1404


>gi|189011566 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 37.7 bits (86), Expect = 0.043
 Identities = 84/385 (21%), Positives = 139/385 (36%), Gaps = 74/385 (19%)

Query: 344  GEEENCHPRGEKSSMERLLTEKNAVIESLQEQVNNAKEKIVRLMSAECTYDLP--EGAAP 401
            G+     PRG K S++  L+     +     Q+  + +   R  S + T   P  +  + 
Sbjct: 2264 GQTATTSPRGAKPSVKSELSP----VARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSR 2319

Query: 402  PASSPNKDVQAVASVHTLAAAQGPSGHLSDFQNDPGMAARDSQCTSGPSSYAQSLEGPGK 461
            P  SP ++     S+        P   LS               TS PS+ +    G GK
Sbjct: 2320 PIQSPGRN-----SISPGRNGISPPNKLSQLPR-----------TSSPSTASTKSSGSGK 2363

Query: 462  DSSFSPGKE-------EKISDSKDFSDHLDSGCSQKPWTEQSLGPERGDQVPMNPSQSLL 514
             S  SPG++       ++   SK+ S    S  + K   + + G     +V ++   S  
Sbjct: 2364 MSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTK 2423

Query: 515  PDRGGSD-------------------PQRQRHLENSE--EPPERRSRVSSVIREKLQEVL 553
                 SD                   P  +R LE S   E     SR +S  R + Q  +
Sbjct: 2424 SSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPV 2483

Query: 554  QDLGLGPEASLSTAPSCHQQTWKNSAAFSPQKMP--LSKELGFSPYMVRRRRAAQRARSH 611
                L P+ SLST  S     W+        K+P  LS  + ++     +R    R+ S 
Sbjct: 2484 LSPSL-PDMSLSTHSSVQAGGWR--------KLPPNLSPTIEYNDGRPAKRHDIARSHSE 2534

Query: 612  FPGSAPSSVGHRANRTVPGAHSRLHVQNGDS-PSLA----PQTTDSRVRRPSSRKPSLPS 666
             P   P       NR+  G   R H ++  S P ++      ++ S +   S       S
Sbjct: 2535 SPSRLP------INRS--GTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKS 2586

Query: 667  DPQDRPGTLEGSKQSQTEPEGARGS 691
            + +    ++ G+KQS+     A+G+
Sbjct: 2587 EDEKHVNSISGTKQSKENQVSAKGT 2611



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 9/95 (9%)

Query: 657  PSSRKPSLPSDPQDRPGTLEGSKQSQTEPEGARGSKAAFLRQPSGSGRAPSPAAPCLSKA 716
            P S  P++   P+ +   L+GS  S    E AR     F    S   ++PS +     K+
Sbjct: 1319 PVSEVPAVSQHPRTKSSRLQGSSLSS---ESARHKAVEF----SSGAKSPSKSGAQTPKS 1371

Query: 717  SPDLPEQWQLWPPVPSGCASLSSQHSYFDTESSSS 751
             P+     Q  P + S C S+SS  S+     +SS
Sbjct: 1372 PPE--HYVQETPLMFSRCTSVSSLDSFESRSIASS 1404


>gi|53759122 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 37.7 bits (86), Expect = 0.043
 Identities = 84/385 (21%), Positives = 139/385 (36%), Gaps = 74/385 (19%)

Query: 344  GEEENCHPRGEKSSMERLLTEKNAVIESLQEQVNNAKEKIVRLMSAECTYDLP--EGAAP 401
            G+     PRG K S++  L+     +     Q+  + +   R  S + T   P  +  + 
Sbjct: 2264 GQTATTSPRGAKPSVKSELSP----VARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSR 2319

Query: 402  PASSPNKDVQAVASVHTLAAAQGPSGHLSDFQNDPGMAARDSQCTSGPSSYAQSLEGPGK 461
            P  SP ++     S+        P   LS               TS PS+ +    G GK
Sbjct: 2320 PIQSPGRN-----SISPGRNGISPPNKLSQLPR-----------TSSPSTASTKSSGSGK 2363

Query: 462  DSSFSPGKE-------EKISDSKDFSDHLDSGCSQKPWTEQSLGPERGDQVPMNPSQSLL 514
             S  SPG++       ++   SK+ S    S  + K   + + G     +V ++   S  
Sbjct: 2364 MSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTK 2423

Query: 515  PDRGGSD-------------------PQRQRHLENSE--EPPERRSRVSSVIREKLQEVL 553
                 SD                   P  +R LE S   E     SR +S  R + Q  +
Sbjct: 2424 SSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPV 2483

Query: 554  QDLGLGPEASLSTAPSCHQQTWKNSAAFSPQKMP--LSKELGFSPYMVRRRRAAQRARSH 611
                L P+ SLST  S     W+        K+P  LS  + ++     +R    R+ S 
Sbjct: 2484 LSPSL-PDMSLSTHSSVQAGGWR--------KLPPNLSPTIEYNDGRPAKRHDIARSHSE 2534

Query: 612  FPGSAPSSVGHRANRTVPGAHSRLHVQNGDS-PSLA----PQTTDSRVRRPSSRKPSLPS 666
             P   P       NR+  G   R H ++  S P ++      ++ S +   S       S
Sbjct: 2535 SPSRLP------INRS--GTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKS 2586

Query: 667  DPQDRPGTLEGSKQSQTEPEGARGS 691
            + +    ++ G+KQS+     A+G+
Sbjct: 2587 EDEKHVNSISGTKQSKENQVSAKGT 2611



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 9/95 (9%)

Query: 657  PSSRKPSLPSDPQDRPGTLEGSKQSQTEPEGARGSKAAFLRQPSGSGRAPSPAAPCLSKA 716
            P S  P++   P+ +   L+GS  S    E AR     F    S   ++PS +     K+
Sbjct: 1319 PVSEVPAVSQHPRTKSSRLQGSSLSS---ESARHKAVEF----SSGAKSPSKSGAQTPKS 1371

Query: 717  SPDLPEQWQLWPPVPSGCASLSSQHSYFDTESSSS 751
             P+     Q  P + S C S+SS  S+     +SS
Sbjct: 1372 PPE--HYVQETPLMFSRCTSVSSLDSFESRSIASS 1404


>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
          Length = 962

 Score = 37.7 bits (86), Expect = 0.043
 Identities = 65/273 (23%), Positives = 101/273 (36%), Gaps = 47/273 (17%)

Query: 494 EQSLGPERGDQVPMNPSQSLLPDRGGSDPQRQRHLENS-------------EEPPERRSR 540
           +Q + P+RG + P  P+   LP  GG+  +R R   +S             E+P  R + 
Sbjct: 282 QQDVAPDRGPE-PGPPAP--LPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPAT 338

Query: 541 VSSVIREKLQEVLQDLGLGPEASLSTAPSCHQQTWKNSAAFSPQKMPLSKELGFSPYMVR 600
                 E    +  +    PE   +  P   +Q  +     +P   P +     +  +V 
Sbjct: 339 PELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGE-----APPAGPCAPATDKAEEVVC 393

Query: 601 RRRAAQRARSHFPGSAPSSVGHRANRTVPGAHSRLHVQNGDSPSLAPQTTDSRVRRPSSR 660
              A +   S FP + P         T P A S       ++PS       S  +     
Sbjct: 394 ---APEDVASPFPTAIPEG-DTTPPETDPAATS-------EAPSARDGPERSVPKEAEPT 442

Query: 661 KPSLPSDPQDRPGTL-EGSKQSQTEPEGARGSKAAFLRQPSGSGRAPSPAAP--CLS--- 714
            P LP + +  PG   E  ++++TEPE   G++   +     +  APSP AP  CL    
Sbjct: 443 PPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRP 502

Query: 715 -------KASPDLPEQWQLWPPVPSGCASLSSQ 740
                   ASP L       PPV  G  SL ++
Sbjct: 503 AAASEGPAASPPLAAAES--PPVEPGPGSLDAE 533



 Score = 34.7 bits (78), Expect = 0.37
 Identities = 58/275 (21%), Positives = 86/275 (31%), Gaps = 28/275 (10%)

Query: 498 GPERGDQVPMNPSQSLLPDRG----GSDPQRQRHLENSEE-----PPERRSRVSSV---- 544
           GPER       P+  +LPD      G  P+ +R  E   E      PER     S     
Sbjct: 430 GPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAP 489

Query: 545 --------IREKLQEVLQDLGLGPEASLSTAPSCHQQTWKNSAAFSPQKMPLSKELGFSP 596
                   ++ +     +     P  + + +P          A  +  + P ++     P
Sbjct: 490 SPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPP 549

Query: 597 YMVRR---RRAAQRARSHFPGSAPSSVGHRANRTVPGAHSRLHVQNGDSPSLAPQTTDSR 653
               R    R A+R  +   G+   SV     R  PG    L   +G  P LA      R
Sbjct: 550 AGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLP-LARSGPVWR 608

Query: 654 VRRPSSRKPSLPSDPQDRPGTLEGSKQSQTEPEGARGSKAAFLRQPSGSGRAPSPAAPCL 713
                     LP     +PG  + +++   +      S A   + P  +  AP    PC 
Sbjct: 609 SEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCP 668

Query: 714 SKASPDLPEQWQLWPPVPSGCASLSSQHSYFDTES 748
           +   P   E      P P    S S    Y D  S
Sbjct: 669 AAQEPAPSEDRN---PFPVKLRSTSLSLKYRDGAS 700


>gi|14249464 zinc finger and BTB domain containing 45 [Homo sapiens]
          Length = 511

 Score = 37.7 bits (86), Expect = 0.043
 Identities = 44/155 (28%), Positives = 63/155 (40%), Gaps = 25/155 (16%)

Query: 613 PGSAPSSVGHRANRTV-------PGA-HSRLHVQNGDSPSLAPQTTDSRVRRPSSRKPSL 664
           P  AP+ + HR    +       PGA HSR   Q       AP T  ++   P +  PSL
Sbjct: 142 PPLAPAQLRHRLRHLLAARPPGHPGAAHSRKQRQPARLQLPAPPTP-AKAEGPDA-DPSL 199

Query: 665 PSDPQDRPGTLEGSKQSQTEPEGARGSKAAFLRQPSGSGRAPSPAAPC----LSKASPDL 720
            + P DR    E  ++S  E +G  G          G G+AP     C    L+ A+   
Sbjct: 200 SAAPDDRGD--EDDEESDDETDGEDGEGGG-----PGEGQAPPSFPDCAAGFLTAAADSA 252

Query: 721 PEQWQLWPPVPSGCASLSSQHSYFDTESSSSDEFF 755
            E+    PP P+G A  S     F   + S+++ F
Sbjct: 253 CEE----PPAPTGLADYSGAGRDFLRGAGSAEDVF 283


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,856,025
Number of Sequences: 37866
Number of extensions: 1833645
Number of successful extensions: 9383
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 363
Number of HSP's that attempted gapping in prelim test: 8781
Number of HSP's gapped (non-prelim): 947
length of query: 814
length of database: 18,247,518
effective HSP length: 111
effective length of query: 703
effective length of database: 14,044,392
effective search space: 9873207576
effective search space used: 9873207576
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.