Search of human proteins with 23308551

Search of human proteins with 23308551

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23308551 potassium channel tetramerisation domain containing
7 [Homo sapiens]
         (289 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23308551 potassium channel tetramerisation domain containing ...   602   e-172
gi|142356950 potassium channel tetramerisation domain containing...   143   2e-34
gi|189571693 potassium channel tetramerisation domain containing...    92   7e-19
gi|189571691 potassium channel tetramerisation domain containing...    92   7e-19
gi|13994353 potassium channel tetramerisation domain containing ...    81   1e-15
gi|71143104 potassium channel tetramerisation domain containing ...    80   3e-15
gi|30578412 potassium channel tetramerisation domain containing ...    78   8e-15
gi|38198663 potassium channel tetramerisation domain containing ...    75   7e-14
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]                  72   7e-13
gi|194018443 potassium channel tetramerisation domain containing...    70   3e-12
gi|194018441 potassium channel tetramerisation domain containing...    70   3e-12
gi|194018439 potassium channel tetramerisation domain containing...    70   3e-12
gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo...    69   4e-12
gi|146198864 potassium channel tetramerisation domain containing...    69   4e-12
gi|46255026 potassium channel tetramerisation domain containing ...    67   2e-11
gi|45387953 potassium channel tetramerization domain containing ...    65   7e-11
gi|55926200 potassium channel tetramerisation domain containing ...    64   2e-10
gi|19923973 potassium channel tetramerisation domain containing ...    62   4e-10
gi|218505694 potassium channel tetramerisation domain containing...    62   4e-10
gi|209969708 potassium channel tetramerisation domain containing...    62   4e-10
gi|40217617 potassium channel tetramerisation domain containing ...    62   4e-10
gi|169234778 potassium channel tetramerisation domain containing...    62   8e-10
gi|39753959 potassium channel tetramerisation domain containing ...    59   6e-09
gi|27436981 potassium voltage-gated channel, Shal-related subfam...    56   3e-08
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]       56   4e-08
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]       56   4e-08
gi|51036594 potassium channel tetramerisation domain containing ...    54   1e-07
gi|9506651 potassium channel tetramerisation domain containing 5...    54   2e-07
gi|169184031 PREDICTED: similar to potassium channel tetramerisa...    52   6e-07
gi|169179790 PREDICTED: similar to potassium channel tetramerisa...    52   6e-07

>gi|23308551 potassium channel tetramerisation domain containing 7
           [Homo sapiens]
          Length = 289

 Score =  602 bits (1551), Expect = e-172
 Identities = 289/289 (100%), Positives = 289/289 (100%)

Query: 1   MVVVTGREPDSRRQDGAMSSSDAEDDFLEPATPTATQAGHALPLLPQEFPEVVPLNIGGA 60
           MVVVTGREPDSRRQDGAMSSSDAEDDFLEPATPTATQAGHALPLLPQEFPEVVPLNIGGA
Sbjct: 1   MVVVTGREPDSRRQDGAMSSSDAEDDFLEPATPTATQAGHALPLLPQEFPEVVPLNIGGA 60

Query: 61  HFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFLRSGDLPPRE 120
           HFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFLRSGDLPPRE
Sbjct: 61  HFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFLRSGDLPPRE 120

Query: 121 RVRAVYKEAQYYAIGPLLEQLENMQPLKGEKVRQAFLGLMPYYKDHLERIVEIARLRAVQ 180
           RVRAVYKEAQYYAIGPLLEQLENMQPLKGEKVRQAFLGLMPYYKDHLERIVEIARLRAVQ
Sbjct: 121 RVRAVYKEAQYYAIGPLLEQLENMQPLKGEKVRQAFLGLMPYYKDHLERIVEIARLRAVQ 180

Query: 181 RKARFAKLKVCVFKEEMPITPYECPLLNSLRFERSESDGQLFEHHCEVDVSFGPWEAVAD 240
           RKARFAKLKVCVFKEEMPITPYECPLLNSLRFERSESDGQLFEHHCEVDVSFGPWEAVAD
Sbjct: 181 RKARFAKLKVCVFKEEMPITPYECPLLNSLRFERSESDGQLFEHHCEVDVSFGPWEAVAD 240

Query: 241 VYDLLHCLVTDLSAQGLTVDHQCIGVCDKHLVNHYYCKRPIYEFKITWW 289
           VYDLLHCLVTDLSAQGLTVDHQCIGVCDKHLVNHYYCKRPIYEFKITWW
Sbjct: 241 VYDLLHCLVTDLSAQGLTVDHQCIGVCDKHLVNHYYCKRPIYEFKITWW 289


>gi|142356950 potassium channel tetramerisation domain containing 14
           [Homo sapiens]
          Length = 255

 Score =  143 bits (360), Expect = 2e-34
 Identities = 95/240 (39%), Positives = 137/240 (57%), Gaps = 20/240 (8%)

Query: 52  VVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFL 111
           VV LN+GG   TT L TLR +  + LA MFS      TD+EGR+FIDR  T+F  +L++L
Sbjct: 34  VVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPILDYL 93

Query: 112 RSGDLPPRERVRAVYKEAQYYAIGPLLEQLENMQPLKGEKV-RQAFLGLMPYYKDHLERI 170
           R+G + P + +  VY+EAQ+Y I PL++ LE+M  + GE+V R+ FL  +P Y ++LE +
Sbjct: 94  RTGQV-PTQHIPEVYREAQFYEIKPLVKLLEDMPQIFGEQVSRKQFLLQVPGYSENLELM 152

Query: 171 VEIARLRAVQRKARFAKLKVCVFKEEMPITPYECPLLNSLRFERSESDGQLFEHHCEVDV 230
           V +AR  A+   AR + + VC+ + E     Y   +L  L+      D ++F+      V
Sbjct: 153 VRLARAEAI--TARKSSVLVCLVETEEQ-DAYYSEVLCFLQ------DKKMFKS----VV 199

Query: 231 SFGPWEAVADVYDLLHCLVTDLSAQGLTVDHQ-CIGVCDKHLVNHYYCKRPIYEFKITWW 289
            FGPW+AV D  DL+HCL  D+ AQG  V  +  +    K    H+     IY F  TWW
Sbjct: 200 KFGPWKAVLDNSDLMHCLEMDIKAQGYKVFSKFYLTYPTKRNEFHF----NIYSFTFTWW 255


>gi|189571693 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 91.7 bits (226), Expect = 7e-19
 Identities = 68/211 (32%), Positives = 105/211 (49%), Gaps = 23/211 (10%)

Query: 53  VPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFLR 112
           V LN+GG  +TT L+TL  Y D+ML AMF G      D +G YFIDRDG  F  VLNFLR
Sbjct: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73

Query: 113 SGDLP---PRERVRAVYKEAQYYAIGPLLEQLENMQPLKGEKVRQAFLGLMPYYKDHLER 169
           + +L      +    + KEA +Y I PL++ L + +PL              Y  D  E 
Sbjct: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPL--------------YPMDTFEE 119

Query: 170 IVEIARLRAVQRKARFAKLKVCVFKEEMPITPYECPLLNSLRFERSESDGQLFE-HHCEV 228
           +VE++  R + + +      V V   ++ IT     LL  +    ++ +  + +   C+V
Sbjct: 120 VVELSSTRKLSKYSN----PVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQV 175

Query: 229 DVSFGPWEAVADVYDLLHCLVTDLSAQGLTV 259
             +FGP +   +V   +H L+  ++ QG T+
Sbjct: 176 SFTFGPCDYHQEVSLRVH-LMEYITKQGFTI 205


>gi|189571691 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 91.7 bits (226), Expect = 7e-19
 Identities = 68/211 (32%), Positives = 105/211 (49%), Gaps = 23/211 (10%)

Query: 53  VPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFLR 112
           V LN+GG  +TT L+TL  Y D+ML AMF G      D +G YFIDRDG  F  VLNFLR
Sbjct: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73

Query: 113 SGDLP---PRERVRAVYKEAQYYAIGPLLEQLENMQPLKGEKVRQAFLGLMPYYKDHLER 169
           + +L      +    + KEA +Y I PL++ L + +PL              Y  D  E 
Sbjct: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPL--------------YPMDTFEE 119

Query: 170 IVEIARLRAVQRKARFAKLKVCVFKEEMPITPYECPLLNSLRFERSESDGQLFE-HHCEV 228
           +VE++  R + + +      V V   ++ IT     LL  +    ++ +  + +   C+V
Sbjct: 120 VVELSSTRKLSKYSN----PVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQV 175

Query: 229 DVSFGPWEAVADVYDLLHCLVTDLSAQGLTV 259
             +FGP +   +V   +H L+  ++ QG T+
Sbjct: 176 SFTFGPCDYHQEVSLRVH-LMEYITKQGFTI 205


>gi|13994353 potassium channel tetramerisation domain containing 10
           [Homo sapiens]
          Length = 313

 Score = 80.9 bits (198), Expect = 1e-15
 Identities = 44/93 (47%), Positives = 59/93 (63%), Gaps = 4/93 (4%)

Query: 53  VPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFLR 112
           V LN+GGA + T + TL   +DTML AMFSGR  + TDSEG   IDR G HFG +LN+LR
Sbjct: 34  VKLNVGGALYYTTMQTLT-KQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLR 92

Query: 113 SGDLP---PRERVRAVYKEAQYYAIGPLLEQLE 142
            G +P    R  +  +  EA+YY +  L+E+ +
Sbjct: 93  DGAVPLPESRREIEELLAEAKYYLVQGLVEECQ 125


>gi|71143104 potassium channel tetramerisation domain containing 21
           [Homo sapiens]
          Length = 260

 Score = 79.7 bits (195), Expect = 3e-15
 Identities = 44/110 (40%), Positives = 66/110 (60%), Gaps = 3/110 (2%)

Query: 53  VPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFLR 112
           + LN+GG  +TT L+TL  + D+ML AMFSG+     DS+G  FIDRDG  F  +LNFLR
Sbjct: 5   ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYILNFLR 64

Query: 113 SG--DLPPR-ERVRAVYKEAQYYAIGPLLEQLENMQPLKGEKVRQAFLGL 159
           +   DLP   + +  + +EA +Y + PL+E L+  +    +  + A L +
Sbjct: 65  TSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELSKAEKNAMLNI 114


>gi|30578412 potassium channel tetramerisation domain containing 13
           [Homo sapiens]
          Length = 329

 Score = 78.2 bits (191), Expect = 8e-15
 Identities = 51/122 (41%), Positives = 68/122 (55%), Gaps = 10/122 (8%)

Query: 28  LEPATPTATQAGHAL----PLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSG 83
           LE   P+  + G A     PL P    + V LN+GG+   T L TL   +DTML AMFSG
Sbjct: 16  LEAPKPSGLEPGPAAYGLKPLTPNS--KYVKLNVGGSLHYTTLRTLTG-QDTMLKAMFSG 72

Query: 84  RHYIPTDSEGRYFIDRDGTHFGDVLNFLRSGDLPPRERVRAVYK---EAQYYAIGPLLEQ 140
           R  + TD+ G   IDR G HFG +LN+LR G +P  E  R + +   EA+YY +  L+E 
Sbjct: 73  RVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIED 132

Query: 141 LE 142
            +
Sbjct: 133 CQ 134


>gi|38198663 potassium channel tetramerisation domain containing 8
           [Homo sapiens]
          Length = 473

 Score = 75.1 bits (183), Expect = 7e-14
 Identities = 49/126 (38%), Positives = 69/126 (54%), Gaps = 18/126 (14%)

Query: 31  ATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFS-------- 82
           ++P A+ A    P  P  FPEVV LN+GG  + T+ STL    D+ LA+MFS        
Sbjct: 24  SSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGA 83

Query: 83  -GRHYIPTDSEGRYFIDRDGTHFGDVLNFLRSGDL------PPRERVRAVYKEAQYYAIG 135
             R  +P DS  R+FIDRDG  F  VL++LR   L      P +ER   + +EA+Y+ + 
Sbjct: 84  RRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKER---LLREAEYFQLT 140

Query: 136 PLLEQL 141
            L++ L
Sbjct: 141 DLVKLL 146


>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
          Length = 707

 Score = 71.6 bits (174), Expect = 7e-13
 Identities = 39/98 (39%), Positives = 57/98 (58%), Gaps = 1/98 (1%)

Query: 51  EVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNF 110
           EV+ LN+GG  F+T   TL    D+  +++ SGR     D  G  FIDRD T F  +LNF
Sbjct: 19  EVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNF 78

Query: 111 LRSGDLPPR-ERVRAVYKEAQYYAIGPLLEQLENMQPL 147
           LR+ +L PR     ++  EAQ+Y + PL+ +L+  + L
Sbjct: 79  LRTKELDPRGVHGSSLLHEAQFYGLTPLVRRLQLREEL 116


>gi|194018443 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 45/128 (35%), Positives = 73/128 (57%), Gaps = 5/128 (3%)

Query: 30  PATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPT 89
           P +P A Q G  LP    +    V +++GG  +T+ L+TL  Y D+ ++ +F+G   I  
Sbjct: 36  PVSPLAAQ-GIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVL 94

Query: 90  DS-EGRYFIDRDGTHFGDVLNFLRSGDLPPRERVR---AVYKEAQYYAIGPLLEQLENMQ 145
           DS +  YFIDRDG  F  VL+FLR+  L   +  +    +Y+EA+YY + P++ +LE  Q
Sbjct: 95  DSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQ 154

Query: 146 PLKGEKVR 153
             + ++ R
Sbjct: 155 QEQEQRRR 162


>gi|194018441 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 45/128 (35%), Positives = 73/128 (57%), Gaps = 5/128 (3%)

Query: 30  PATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPT 89
           P +P A Q G  LP    +    V +++GG  +T+ L+TL  Y D+ ++ +F+G   I  
Sbjct: 36  PVSPLAAQ-GIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVL 94

Query: 90  DS-EGRYFIDRDGTHFGDVLNFLRSGDLPPRERVR---AVYKEAQYYAIGPLLEQLENMQ 145
           DS +  YFIDRDG  F  VL+FLR+  L   +  +    +Y+EA+YY + P++ +LE  Q
Sbjct: 95  DSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQ 154

Query: 146 PLKGEKVR 153
             + ++ R
Sbjct: 155 QEQEQRRR 162


>gi|194018439 potassium channel tetramerisation domain containing 15
           isoform 1 [Homo sapiens]
          Length = 234

 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 45/128 (35%), Positives = 73/128 (57%), Gaps = 5/128 (3%)

Query: 30  PATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPT 89
           P +P A Q G  LP    +    V +++GG  +T+ L+TL  Y D+ ++ +F+G   I  
Sbjct: 36  PVSPLAAQ-GIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVL 94

Query: 90  DS-EGRYFIDRDGTHFGDVLNFLRSGDLPPRERVR---AVYKEAQYYAIGPLLEQLENMQ 145
           DS +  YFIDRDG  F  VL+FLR+  L   +  +    +Y+EA+YY + P++ +LE  Q
Sbjct: 95  DSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQ 154

Query: 146 PLKGEKVR 153
             + ++ R
Sbjct: 155 QEQEQRRR 162


>gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo
           sapiens]
          Length = 316

 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 39/94 (41%), Positives = 56/94 (59%), Gaps = 4/94 (4%)

Query: 53  VPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFLR 112
           V LN+GG+ + T +  L  + DTML AMFSGR  + TD EG   IDR G HFG +LN+LR
Sbjct: 30  VQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLR 88

Query: 113 SGDL---PPRERVRAVYKEAQYYAIGPLLEQLEN 143
              +     R+ ++ +  EA+YY I  L+   ++
Sbjct: 89  DDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQS 122


>gi|146198864 potassium channel tetramerisation domain containing 4
           [Homo sapiens]
          Length = 259

 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 37/95 (38%), Positives = 59/95 (62%), Gaps = 3/95 (3%)

Query: 52  VVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFL 111
           ++ LN+GG  + T+  TL  Y DT L  + +G+   P D++G YFIDRDG  F  VLNFL
Sbjct: 34  LMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFL 93

Query: 112 RSGDLPPRERVR---AVYKEAQYYAIGPLLEQLEN 143
           R+G+L   E  R    + +EA+++ +  L E++++
Sbjct: 94  RNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKS 128


>gi|46255026 potassium channel tetramerisation domain containing 3
           [Homo sapiens]
          Length = 815

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 36/92 (39%), Positives = 52/92 (56%), Gaps = 1/92 (1%)

Query: 51  EVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNF 110
           E+V LN+GG  F+T   TL    D+  +++ SGR     D  G  FIDRD   F  +LNF
Sbjct: 18  EIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNF 77

Query: 111 LRSGDLPPR-ERVRAVYKEAQYYAIGPLLEQL 141
           LR+ +L  R   +  +  EA++Y I PL+ +L
Sbjct: 78  LRTKELDLRGVSINVLRHEAEFYGITPLVRRL 109


>gi|45387953 potassium channel tetramerization domain containing 18
           [Homo sapiens]
          Length = 426

 Score = 65.1 bits (157), Expect = 7e-11
 Identities = 37/90 (41%), Positives = 56/90 (62%), Gaps = 2/90 (2%)

Query: 47  QEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGD 106
           +E  +V+ LN+GG  +T R  +L  ++D+MLA+MFSGR  + TD  G   IDRDG  F  
Sbjct: 8   EEVLDVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKY 67

Query: 107 VLNFLRSG-DLPPRERVR-AVYKEAQYYAI 134
           +L++L     +P  E+ R A+ +EA Y+ I
Sbjct: 68  LLDYLHGEVQIPTDEQTRIALQEEADYFGI 97


>gi|55926200 potassium channel tetramerisation domain containing 16
           [Homo sapiens]
          Length = 428

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 40/107 (37%), Positives = 63/107 (58%), Gaps = 13/107 (12%)

Query: 45  LPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGR----HYIPTDSEGRYFIDRD 100
           +P  FPEVV LN+GG  + TR STL     ++L  MFS +    + +  DS+GR+FIDRD
Sbjct: 19  VPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRD 78

Query: 101 GTHFGDVLNFLRSGDL------PPRERVRAVYKEAQYYAIGPLLEQL 141
           G  F  +L++LR   +      P + R++   +EA+Y+ +  L++ L
Sbjct: 79  GFLFRYILDYLRDRQVVLPDHFPEKGRLK---REAEYFQLPDLVKLL 122


>gi|19923973 potassium channel tetramerisation domain containing 12
           [Homo sapiens]
          Length = 325

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 37/104 (35%), Positives = 61/104 (58%), Gaps = 11/104 (10%)

Query: 46  PQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGR--HYIPTDSEGRYFIDRDGTH 103
           P  FP++V LN+GG  + TR  T+    D++L  MF+ +    +  DS+GR+F+DRDG  
Sbjct: 29  PPLFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFL 88

Query: 104 FGDVLNFLRSGDL------PPRERVRAVYKEAQYYAIGPLLEQL 141
           F  +L++LR   L      P R R++   +EA+Y+ +  L+ +L
Sbjct: 89  FRYILDYLRDLQLVLPDYFPERSRLQ---REAEYFELPELVRRL 129


>gi|218505694 potassium channel tetramerisation domain containing 1
           isoform b [Homo sapiens]
          Length = 865

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 40/117 (34%), Positives = 65/117 (55%), Gaps = 5/117 (4%)

Query: 30  PATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPT 89
           PA+P   Q G   P    +    V +++GG  +T+ L+TL  Y ++ +  +F G   I  
Sbjct: 618 PASPLNNQ-GIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVL 676

Query: 90  DS-EGRYFIDRDGTHFGDVLNFLRSGDLPPRERVR---AVYKEAQYYAIGPLLEQLE 142
           DS +  YFIDRDG  F  +LNFLR+  L   +  +    +Y+EA+Y+ + P+L ++E
Sbjct: 677 DSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEME 733


>gi|209969708 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 40/117 (34%), Positives = 65/117 (55%), Gaps = 5/117 (4%)

Query: 30  PATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPT 89
           PA+P   Q G   P    +    V +++GG  +T+ L+TL  Y ++ +  +F G   I  
Sbjct: 10  PASPLNNQ-GIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVL 68

Query: 90  DS-EGRYFIDRDGTHFGDVLNFLRSGDLPPRERVR---AVYKEAQYYAIGPLLEQLE 142
           DS +  YFIDRDG  F  +LNFLR+  L   +  +    +Y+EA+Y+ + P+L ++E
Sbjct: 69  DSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEME 125


>gi|40217617 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 40/117 (34%), Positives = 65/117 (55%), Gaps = 5/117 (4%)

Query: 30  PATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPT 89
           PA+P   Q G   P    +    V +++GG  +T+ L+TL  Y ++ +  +F G   I  
Sbjct: 10  PASPLNNQ-GIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVL 68

Query: 90  DS-EGRYFIDRDGTHFGDVLNFLRSGDLPPRERVR---AVYKEAQYYAIGPLLEQLE 142
           DS +  YFIDRDG  F  +LNFLR+  L   +  +    +Y+EA+Y+ + P+L ++E
Sbjct: 69  DSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEME 125


>gi|169234778 potassium channel tetramerisation domain containing 17
           [Homo sapiens]
          Length = 297

 Score = 61.6 bits (148), Expect = 8e-10
 Identities = 39/105 (37%), Positives = 55/105 (52%), Gaps = 3/105 (2%)

Query: 53  VPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHY-IPTDSEGRYFIDRDGTHFGDVLNFL 111
           V LN+GG  F T   TL   + + L+ +  G       D  G Y IDRD T+FG +LNFL
Sbjct: 33  VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFL 92

Query: 112 RSGDLPPRERV--RAVYKEAQYYAIGPLLEQLENMQPLKGEKVRQ 154
           R G L   + +    V +EA++Y IGPL+  +++    K   V Q
Sbjct: 93  RHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKDRMEEKDYTVTQ 137


>gi|39753959 potassium channel tetramerisation domain containing 9
           [Homo sapiens]
          Length = 389

 Score = 58.5 bits (140), Expect = 6e-09
 Identities = 45/131 (34%), Positives = 66/131 (50%), Gaps = 14/131 (10%)

Query: 25  DDFLEPATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYE-DTMLAAMFSG 83
           + F++P T +    G     L     + + LN+GG +FTT  STL   E D+MLA MF  
Sbjct: 68  EPFIDPQTDSKPPEG-----LLGFHTDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKD 122

Query: 84  RHYIPT--DSEGRYFIDRDGTHFGDVLNFLRSGDLPPRERVR--AVYKEAQYYAIGPLLE 139
           +       D  G + IDR   +F  +LN+LR G L   + +    V +EA+++ I  L+E
Sbjct: 123 KGVWGNKQDHRGAFLIDRSPEYFEPILNYLRHGQLIVNDGINLLGVLEEARFFGIDSLIE 182

Query: 140 QLE----NMQP 146
            LE    N QP
Sbjct: 183 HLEVAIKNSQP 193


>gi|27436981 potassium voltage-gated channel, Shal-related
           subfamily, member 1 [Homo sapiens]
          Length = 647

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 39/110 (35%), Positives = 54/110 (49%), Gaps = 15/110 (13%)

Query: 42  LPLLPQEFP-----------EVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTD 90
           LPL  Q  P           EV+ +N+ G  F T  +TL  Y DT+L +  S + +    
Sbjct: 20  LPLAQQPLPPAPGVKASRGDEVLVVNVSGRRFETWKNTLDRYPDTLLGS--SEKEFFYDA 77

Query: 91  SEGRYFIDRDGTHFGDVLNFLRSGDL--PPRERVRAVYKEAQYYAIGPLL 138
             G YF DRD   F  VLNF R+G L  P +E ++A  +E  +Y + P L
Sbjct: 78  DSGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAFYGLVPEL 127


>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
          Length = 229

 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 36/94 (38%), Positives = 53/94 (56%), Gaps = 3/94 (3%)

Query: 51  EVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNF 110
           E+V LN+GG  FTTR ST++ +  + LA M  GR        G+ F+DRDG  F  +L+F
Sbjct: 5   ELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDF 64

Query: 111 LRSGD-LPPRE--RVRAVYKEAQYYAIGPLLEQL 141
           LR+   L P E      + +EA +Y +  L++ L
Sbjct: 65  LRTHQLLLPTEFSDYLRLQREALFYELRSLVDLL 98


>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
          Length = 272

 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 36/94 (38%), Positives = 53/94 (56%), Gaps = 3/94 (3%)

Query: 51  EVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNF 110
           E+V LN+GG  FTTR ST++ +  + LA M  GR        G+ F+DRDG  F  +L+F
Sbjct: 5   ELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDF 64

Query: 111 LRSGD-LPPRE--RVRAVYKEAQYYAIGPLLEQL 141
           LR+   L P E      + +EA +Y +  L++ L
Sbjct: 65  LRTHQLLLPTEFSDYLRLQREALFYELRSLVDLL 98


>gi|51036594 potassium channel tetramerisation domain containing 11
           [Homo sapiens]
          Length = 232

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 51/166 (30%), Positives = 73/166 (43%), Gaps = 12/166 (7%)

Query: 76  MLAAMFSGRHYIP----TDSEGRYFIDRDGTHFGDVLNFLRSG--DLPPRERVRAVYK-E 128
           ML AMF     +P    +   G YFIDRDG  F  +LNFLR G  DLP      A+ + E
Sbjct: 1   MLGAMFRAGTPMPPNLNSQGGGHYFIDRDGKAFRHILNFLRLGRLDLPRGYGETALLRAE 60

Query: 129 AQYYAIGPLLEQLENMQPLKGEKVRQAFLGLMPYYKDHLERIVEIARLRAVQRKARFAKL 188
           A +Y I PLL+ L  ++  +G     A   L+    D   R+V  +  R        + +
Sbjct: 61  ADFYQIRPLLDALRELEASQGTPAPTA--ALLHADVDVSPRLVHFSARRG-PHHYELSSV 117

Query: 189 KVCVFKEEMPITPYECPLLNSLRFERSESDGQLFEHHCEVDVSFGP 234
           +V  F+  +  T  EC  L +LR     + G   E      + + P
Sbjct: 118 QVDTFRANLFCTDSEC--LGALRARFGVASGDRAEGSPHFHLEWAP 161


>gi|9506651 potassium channel tetramerisation domain containing 5
           [Homo sapiens]
          Length = 234

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 38/118 (32%), Positives = 59/118 (50%), Gaps = 4/118 (3%)

Query: 41  ALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSE--GRYFID 98
           AL   P    + V LN+GG +F T   TL     + L  +      + +D +  G Y ID
Sbjct: 34  ALAQRPGSVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLID 93

Query: 99  RDGTHFGDVLNFLRSGDLPPRERV--RAVYKEAQYYAIGPLLEQLENMQPLKGEKVRQ 154
           RD T+FG VLN+LR G L   + +    V +EA++Y I  L++ +++    +  K  Q
Sbjct: 94  RDPTYFGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKTSQ 151


>gi|169184031 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 42/131 (32%), Positives = 65/131 (49%), Gaps = 14/131 (10%)

Query: 25  DDFLEPATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYE-DTMLAAMFSG 83
           + F++P T +    G     L     + + L++GG +FTT  STL   E D MLA MF  
Sbjct: 68  EPFIDPQTDSKPPEG-----LLGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKD 122

Query: 84  RHYIPT--DSEGRYFIDRDGTHFGDVLNFLRSGDLPPRERV--RAVYKEAQYYAIGPLLE 139
           +       D  G + ID+   +F  +LN+LR G L   + +    V +EA+++ I  L+E
Sbjct: 123 KGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSLIE 182

Query: 140 QL----ENMQP 146
            L    +N QP
Sbjct: 183 HLKVAIKNSQP 193


>gi|169179790 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 42/131 (32%), Positives = 65/131 (49%), Gaps = 14/131 (10%)

Query: 25  DDFLEPATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYE-DTMLAAMFSG 83
           + F++P T +    G     L     + + L++GG +FTT  STL   E D MLA MF  
Sbjct: 68  EPFIDPQTDSKPPEG-----LLGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKD 122

Query: 84  RHYIPT--DSEGRYFIDRDGTHFGDVLNFLRSGDLPPRERV--RAVYKEAQYYAIGPLLE 139
           +       D  G + ID+   +F  +LN+LR G L   + +    V +EA+++ I  L+E
Sbjct: 123 KGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSLIE 182

Query: 140 QL----ENMQP 146
            L    +N QP
Sbjct: 183 HLKVAIKNSQP 193


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,315,857
Number of Sequences: 37866
Number of extensions: 498343
Number of successful extensions: 1417
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 1318
Number of HSP's gapped (non-prelim): 78
length of query: 289
length of database: 18,247,518
effective HSP length: 101
effective length of query: 188
effective length of database: 14,423,052
effective search space: 2711533776
effective search space used: 2711533776
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.