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Search of human proteins with 229577185
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|229577185 epidermal growth factor receptor pathway substrate
15 isoform B [Homo sapiens]
(582 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|229577185 epidermal growth factor receptor pathway substrate ... 1161 0.0
gi|4503593 epidermal growth factor receptor pathway substrate 15... 1094 0.0
gi|10864047 epidermal growth factor receptor pathway substrate 1... 279 4e-75
gi|71061468 centromere protein E [Homo sapiens] 73 8e-13
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 70 7e-12
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 68 2e-11
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 68 2e-11
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 65 2e-10
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 65 2e-10
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 65 2e-10
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 65 2e-10
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 65 2e-10
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 64 3e-10
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 64 3e-10
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 64 4e-10
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 64 4e-10
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 64 4e-10
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 64 5e-10
gi|24308179 CTTNBP2 N-terminal like [Homo sapiens] 62 1e-09
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 62 1e-09
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 61 2e-09
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 61 2e-09
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 60 4e-09
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 60 6e-09
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 60 6e-09
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 60 6e-09
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 59 9e-09
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 59 9e-09
gi|42794779 myosin 18A isoform b [Homo sapiens] 59 9e-09
gi|28416946 myosin 18A isoform a [Homo sapiens] 59 9e-09
>gi|229577185 epidermal growth factor receptor pathway substrate 15
isoform B [Homo sapiens]
Length = 582
Score = 1161 bits (3004), Expect = 0.0
Identities = 582/582 (100%), Positives = 582/582 (100%)
Query: 1 MYLKSDSGLGGWITIPAVADVLKYSCIVCWSSREKNNVEQDLKEKEDTIKQRTSEVQDLQ 60
MYLKSDSGLGGWITIPAVADVLKYSCIVCWSSREKNNVEQDLKEKEDTIKQRTSEVQDLQ
Sbjct: 1 MYLKSDSGLGGWITIPAVADVLKYSCIVCWSSREKNNVEQDLKEKEDTIKQRTSEVQDLQ 60
Query: 61 DEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELT 120
DEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELT
Sbjct: 61 DEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELT 120
Query: 121 SQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQM 180
SQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQM
Sbjct: 121 SQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQM 180
Query: 181 KLMEMKDLENHNSQLNWCSSPHSILVNGATDYCSLSTSSSETANLNEHVEGQSNLESEPI 240
KLMEMKDLENHNSQLNWCSSPHSILVNGATDYCSLSTSSSETANLNEHVEGQSNLESEPI
Sbjct: 181 KLMEMKDLENHNSQLNWCSSPHSILVNGATDYCSLSTSSSETANLNEHVEGQSNLESEPI 240
Query: 241 HQESPARSSPELLPSGVTDENEVTTAVTEKVCSELDNNRHSKEEDPFNVDSSSLTGPVAD 300
HQESPARSSPELLPSGVTDENEVTTAVTEKVCSELDNNRHSKEEDPFNVDSSSLTGPVAD
Sbjct: 241 HQESPARSSPELLPSGVTDENEVTTAVTEKVCSELDNNRHSKEEDPFNVDSSSLTGPVAD 300
Query: 301 TNLDFFQSDPFVGSDPFKDDPFGKIDPFGGDPFKGSDPFASDCFFRQSTDPFATSSTDPF 360
TNLDFFQSDPFVGSDPFKDDPFGKIDPFGGDPFKGSDPFASDCFFRQSTDPFATSSTDPF
Sbjct: 301 TNLDFFQSDPFVGSDPFKDDPFGKIDPFGGDPFKGSDPFASDCFFRQSTDPFATSSTDPF 360
Query: 361 SAANNSSITSVETLKHNDPFAPGGTVVAASDSATDPFASVFGNESFGGGFADFSTLSKVN 420
SAANNSSITSVETLKHNDPFAPGGTVVAASDSATDPFASVFGNESFGGGFADFSTLSKVN
Sbjct: 361 SAANNSSITSVETLKHNDPFAPGGTVVAASDSATDPFASVFGNESFGGGFADFSTLSKVN 420
Query: 421 NEDPFRSATSSSVSNVVITKNVFEETSVKSEDEPPALPPKIGTPTRPCPLPPGKRSINKL 480
NEDPFRSATSSSVSNVVITKNVFEETSVKSEDEPPALPPKIGTPTRPCPLPPGKRSINKL
Sbjct: 421 NEDPFRSATSSSVSNVVITKNVFEETSVKSEDEPPALPPKIGTPTRPCPLPPGKRSINKL 480
Query: 481 DSPDPFKLNDPFQPFPGNDSPKEKDPEIFCDPFTSATTTTNKEADPSNFANFSAYPSEED 540
DSPDPFKLNDPFQPFPGNDSPKEKDPEIFCDPFTSATTTTNKEADPSNFANFSAYPSEED
Sbjct: 481 DSPDPFKLNDPFQPFPGNDSPKEKDPEIFCDPFTSATTTTNKEADPSNFANFSAYPSEED 540
Query: 541 MIEWAKRESEREEEQRLARLNQQEQEDLELAIALSKSEISEA 582
MIEWAKRESEREEEQRLARLNQQEQEDLELAIALSKSEISEA
Sbjct: 541 MIEWAKRESEREEEQRLARLNQQEQEDLELAIALSKSEISEA 582
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 1094 bits (2829), Expect = 0.0
Identities = 550/550 (100%), Positives = 550/550 (100%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA
Sbjct: 347 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 406
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE
Sbjct: 407 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 466
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNWCSSPHSILVNGATDY 212
SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNWCSSPHSILVNGATDY
Sbjct: 467 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNWCSSPHSILVNGATDY 526
Query: 213 CSLSTSSSETANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDENEVTTAVTEKVC 272
CSLSTSSSETANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDENEVTTAVTEKVC
Sbjct: 527 CSLSTSSSETANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDENEVTTAVTEKVC 586
Query: 273 SELDNNRHSKEEDPFNVDSSSLTGPVADTNLDFFQSDPFVGSDPFKDDPFGKIDPFGGDP 332
SELDNNRHSKEEDPFNVDSSSLTGPVADTNLDFFQSDPFVGSDPFKDDPFGKIDPFGGDP
Sbjct: 587 SELDNNRHSKEEDPFNVDSSSLTGPVADTNLDFFQSDPFVGSDPFKDDPFGKIDPFGGDP 646
Query: 333 FKGSDPFASDCFFRQSTDPFATSSTDPFSAANNSSITSVETLKHNDPFAPGGTVVAASDS 392
FKGSDPFASDCFFRQSTDPFATSSTDPFSAANNSSITSVETLKHNDPFAPGGTVVAASDS
Sbjct: 647 FKGSDPFASDCFFRQSTDPFATSSTDPFSAANNSSITSVETLKHNDPFAPGGTVVAASDS 706
Query: 393 ATDPFASVFGNESFGGGFADFSTLSKVNNEDPFRSATSSSVSNVVITKNVFEETSVKSED 452
ATDPFASVFGNESFGGGFADFSTLSKVNNEDPFRSATSSSVSNVVITKNVFEETSVKSED
Sbjct: 707 ATDPFASVFGNESFGGGFADFSTLSKVNNEDPFRSATSSSVSNVVITKNVFEETSVKSED 766
Query: 453 EPPALPPKIGTPTRPCPLPPGKRSINKLDSPDPFKLNDPFQPFPGNDSPKEKDPEIFCDP 512
EPPALPPKIGTPTRPCPLPPGKRSINKLDSPDPFKLNDPFQPFPGNDSPKEKDPEIFCDP
Sbjct: 767 EPPALPPKIGTPTRPCPLPPGKRSINKLDSPDPFKLNDPFQPFPGNDSPKEKDPEIFCDP 826
Query: 513 FTSATTTTNKEADPSNFANFSAYPSEEDMIEWAKRESEREEEQRLARLNQQEQEDLELAI 572
FTSATTTTNKEADPSNFANFSAYPSEEDMIEWAKRESEREEEQRLARLNQQEQEDLELAI
Sbjct: 827 FTSATTTTNKEADPSNFANFSAYPSEEDMIEWAKRESEREEEQRLARLNQQEQEDLELAI 886
Query: 573 ALSKSEISEA 582
ALSKSEISEA
Sbjct: 887 ALSKSEISEA 896
>gi|10864047 epidermal growth factor receptor pathway substrate
15-like 1 [Homo sapiens]
Length = 864
Score = 279 bits (714), Expect = 4e-75
Identities = 192/528 (36%), Positives = 288/528 (54%), Gaps = 89/528 (16%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
REK ++EQD++EKE+ I+Q+TSEVQ+LQ+++ RE ++LQ+L+AQKQ Q+ LDE+D+QKA
Sbjct: 398 REKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKA 457
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
+L + L +VR+KC +E Q+ISSLK ++ SQES + + E++L +A+ EL+RLQQE +LE+
Sbjct: 458 KLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELNRLQQEETQLEQ 517
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNWCSSPHSILVNGATDY 212
S+++G+ QLE + + L+ +Q EI+ + KL + L + + + +++GA
Sbjct: 518 SIQAGRVQLETIIKSLKSTQDEINQARSKLSQ---LHESRQEAHRSLEQYDQVLDGAH-- 572
Query: 213 CSLSTSSSETANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDENEVTTAVTEKVC 272
S ++ ANL+E V S E G D+ A+
Sbjct: 573 ---GASLTDLANLSEGV------------------SLAERGSFGAMDDPFKNKALL---- 607
Query: 273 SELDNNRHSKEEDPFNVDSSSLTGPVADTNLDFFQSDPFVGSDPFKDDPF---------- 322
NN DPF + D F+SDPF G+DPFK DPF
Sbjct: 608 --FSNNTQELHPDPFQTE-------------DPFKSDPFKGADPFKGDPFQNDPFAEQQT 652
Query: 323 GKIDPFGGDPFKGSDPF---ASDCFFRQST--DPFATSSTDPFSAANNSSITSVETLKHN 377
DPFGGDPFK SDPF A+D FF++ T DPF ++DPF+ N S + ++ + +
Sbjct: 653 TSTDPFGGDPFKESDPFRGSATDDFFKKQTKNDPF---TSDPFT-KNPSLPSKLDPFESS 708
Query: 378 DPFAPGGTVVAASDSATDPFASV--FGNESFGG--GFADFSTLSKVNNEDPFRSATSSSV 433
DPF+ + S +DPF ++ FG+ SF GFADFS +SK PF S+ +
Sbjct: 709 DPFSSS----SVSSKGSDPFGTLDPFGSGSFNSAEGFADFSQMSKPPPSGPFTSSLGGA- 763
Query: 434 SNVVITKNVFEETSVKSEDEPPALPPKIGTPTRPCPLPPGKRS-INKLDSPDPFKLNDPF 492
F + KS+ + PALPPK P RP P P GK + +++L S D + DPF
Sbjct: 764 --------GFSDDPFKSKQDTPALPPKKPAPPRPKP-PSGKSTPVSQLGSADFPEAPDPF 814
Query: 493 QPF---PGNDSPKEK---DPEIFCDPFTSATTTTNKEADPSNFANFSA 534
QP G+ +K DP DPF ++ +A S FA+F++
Sbjct: 815 QPLGADSGDPFQSKKGFGDPFSGKDPFVPSSAAKPSKASASGFADFTS 862
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 72.8 bits (177), Expect = 8e-13
Identities = 46/152 (30%), Positives = 84/152 (55%), Gaps = 4/152 (2%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
+QDL+ K + T++V+D +E+ + + L +K ++Q++L+ + +K QL+ L
Sbjct: 1018 KQDLEAKNT--QTLTADVKD--NEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDL 1073
Query: 99 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 158
KE + E + + L EL Q+ ++ + K ELSR AE+EE ++
Sbjct: 1074 KENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKS 1133
Query: 159 AQLEPLQQHLQDSQQEISSMQMKLMEMKDLEN 190
QL+ QQ L + Q+E+S MQ K+ E+++L+N
Sbjct: 1134 QQLQEKQQQLLNVQEEMSEMQKKINEIENLKN 1165
Score = 60.1 bits (144), Expect = 6e-09
Identities = 37/149 (24%), Positives = 76/149 (51%), Gaps = 12/149 (8%)
Query: 49 IKQRTSEVQDLQDEVQRENTNLQKLQ----AQKQQVQELLDELDEQKAQLEEQLKEVRKK 104
+ +R E D V +E +LQ+LQ ++ Q++E + E+ + + EE+LK
Sbjct: 1426 LSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCC 1485
Query: 105 CAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE--------SVES 156
E+ + I+ L+ L+ +E++IST +++L ++L QE E EE V+
Sbjct: 1486 LKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQE 1545
Query: 157 GKAQLEPLQQHLQDSQQEISSMQMKLMEM 185
+L+ ++H + + S++ K++E+
Sbjct: 1546 KVNELKQFKEHRKAKDSALQSIESKMLEL 1574
Score = 54.7 bits (130), Expect = 2e-07
Identities = 38/191 (19%), Positives = 93/191 (48%), Gaps = 2/191 (1%)
Query: 40 QDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLK 99
Q+L+EK +++R +E++ L+++++ ++ LQ ++ +K + E L + E+ L ++ K
Sbjct: 873 QELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQE-K 931
Query: 100 EVRKKCAEEAQLI-SSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 158
+ K+ E Q+ LK+++ + +E+L A E L + Q+ L+ +
Sbjct: 932 DDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEV 991
Query: 159 AQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNWCSSPHSILVNGATDYCSLSTS 218
++ ++++ +++ E + + + +DLE N+Q + ++ SL
Sbjct: 992 SRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQE 1051
Query: 219 SSETANLNEHV 229
+E + E V
Sbjct: 1052 KNELQQMLESV 1062
Score = 53.9 bits (128), Expect = 4e-07
Identities = 32/151 (21%), Positives = 75/151 (49%), Gaps = 4/151 (2%)
Query: 49 IKQRTSEVQDLQDEVQRENTNLQK----LQAQKQQVQELLDELDEQKAQLEEQLKEVRKK 104
+ Q+ E + V +E NL++ L+ ++ Q++E L E + +++++LK R
Sbjct: 1873 LAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARML 1932
Query: 105 CAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPL 164
E + + L+ +++ + QIS +++L K+++EL + QE + E + K +
Sbjct: 1933 SKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMS 1992
Query: 165 QQHLQDSQQEISSMQMKLMEMKDLENHNSQL 195
+ + + +Q + + + M+ + N QL
Sbjct: 1993 HKKINEMEQLKKQFEAQNLSMQSVRMDNFQL 2023
Score = 50.4 bits (119), Expect = 4e-06
Identities = 55/268 (20%), Positives = 111/268 (41%), Gaps = 25/268 (9%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQ----KQQVQELLDELD 88
RE+ + +LK +++ E+QD +E+ + KL ++ + +VQ LL+E+
Sbjct: 740 REEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIG 799
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148
+ K L K +E Q +L + E + EE + +E+ L +E
Sbjct: 800 KTKDDLATTQSNY-KSTDQEFQNFKTLHMDF---EQKYKMVLEENERMNQEIVNLSKEAQ 855
Query: 149 ELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD-LENHNSQLNWCSSPHSI--- 204
+ + S+ + K +L Q LQ+ +E+ ++ ++K+ LEN +S L ++
Sbjct: 856 KFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITE 915
Query: 205 -LVNGATDYCSLSTSSSETANLNEHVEGQSNLESEPIHQ--------ESPARSSPELLPS 255
L + +L+ + L E ++ + + IH + R++ E L
Sbjct: 916 KLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESL-- 973
Query: 256 GVTDENEVTTAVTEKVCSELDNNRHSKE 283
E + K+ E+ N H +E
Sbjct: 974 --KQHQETINTLKSKISEEVSRNLHMEE 999
Score = 50.1 bits (118), Expect = 6e-06
Identities = 38/156 (24%), Positives = 77/156 (49%), Gaps = 10/156 (6%)
Query: 42 LKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEV 101
LKE+++TI + V + D++ +L+ A+ Q+ + L + Q L++ + E
Sbjct: 1783 LKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNET 1842
Query: 102 RKKCAEEAQLISSLKAE---LTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 158
+KK +E QL +K + L+ E + ++L + EE+ + +E L E+ K
Sbjct: 1843 QKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLK 1902
Query: 159 AQLEPLQQHLQDS-------QQEISSMQMKLMEMKD 187
+ + L++ LQ++ QQE+ + +M E K+
Sbjct: 1903 LERDQLKESLQETKARDLEIQQELKTARMLSKEHKE 1938
Score = 48.5 bits (114), Expect = 2e-05
Identities = 49/219 (22%), Positives = 85/219 (38%), Gaps = 12/219 (5%)
Query: 32 SREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQK 91
S E + + + + + + S VQ L +E+ + +L Q+ + +
Sbjct: 767 SEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLH 826
Query: 92 AQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELE 151
E++ K V ++ Q I +L E +S + + EL+ +EL +E E
Sbjct: 827 MDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERL 886
Query: 152 ESVESGKAQLEPLQQHLQDSQQE----ISSMQMKLMEMKDLENHNSQLNWCSSPHSILVN 207
+E K QLE LQ ++E +Q L E+K L L I
Sbjct: 887 NEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQI--- 943
Query: 208 GATDYCSLSTSSSETANLNEHVEGQ--SNLESEPIHQES 244
+ L + +T N+N + Q + LES HQE+
Sbjct: 944 ---ERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQET 979
Score = 47.8 bits (112), Expect = 3e-05
Identities = 57/279 (20%), Positives = 117/279 (41%), Gaps = 48/279 (17%)
Query: 50 KQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDE---------------------LD 88
+++ E++ L+++ + + NL+ ++ + ++ ++L E L
Sbjct: 1640 QEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLK 1699
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148
++ QL+E L+E + E+ + + + L + I +++ E+S +Q++
Sbjct: 1700 VERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKD-- 1757
Query: 149 ELEESVESGKAQLEPLQQ-------HLQDSQQEISSMQMKLME--------MKDLENHNS 193
LE S ++ KAQ +Q+ HL++ Q+ I ++ + E KDLEN N+
Sbjct: 1758 -LEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNA 1816
Query: 194 QL----NWCSSPHSILVNGATDYCSLSTSSSETANLNEHVEGQ----SNLESEPIHQESP 245
+L + L+ D SE L + ++ Q S LE E ++
Sbjct: 1817 KLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQK 1876
Query: 246 ARSSPELLPSGVTDENEVTTAVTEKVCSELDNNRHSKEE 284
+ E + S V E + V E + E D + S +E
Sbjct: 1877 LHENLEEMKS-VMKERDNLRRVEETLKLERDQLKESLQE 1914
Score = 47.0 bits (110), Expect = 5e-05
Identities = 58/266 (21%), Positives = 127/266 (47%), Gaps = 33/266 (12%)
Query: 33 REKNNVEQ----DLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD 88
+EKN++++ + K K+D Q E+ +L++ V+ Q L+ + ELL E +
Sbjct: 529 KEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKE 588
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELA--KAREELSRLQQE 146
+Q +L+E + + +K + L SL++ ++ + + ++ E A+ E + L+ E
Sbjct: 589 DQIKKLQEYI-DSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSE 647
Query: 147 TAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEM-KDLENHNSQLNWCSSPHSIL 205
EL+E ++ + ++ +Q Q ++ + + +++ K+L++ +++ +S L
Sbjct: 648 NLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTS----L 703
Query: 206 VNGATD---YCSLSTSSSET---ANLNEHVEGQSNLESEPIHQESPARSSPELLPSGV-- 257
++G C+L T LN+ VE E+E + +E S + LPS V
Sbjct: 704 IDGKVPKDLLCNLELEGKITDLQKELNKEVE-----ENEALREEVILLSELKSLPSEVER 758
Query: 258 --------TDENEVTTAVTEKVCSEL 275
++E + T+ +K+ SE+
Sbjct: 759 LRKEIQDKSEELHIITSEKDKLFSEV 784
Score = 46.6 bits (109), Expect = 6e-05
Identities = 32/160 (20%), Positives = 86/160 (53%), Gaps = 8/160 (5%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
++ + E ++ ++T+++ + QD +++ +T LQ+ + QELL + E ++ +E +
Sbjct: 1248 QETIDELRRSVSEKTAQIINTQD-LEKSHTKLQEEIPVLHEEQELLPNVKEV-SETQETM 1305
Query: 99 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 158
E+ + S+ A + + +++ E+ +++EE+ L +E L+ E+ +
Sbjct: 1306 NELELLTEQSTTKDSTTLARIEMERLRLN---EKFQESQEEIKSLTKERDNLKTIKEALE 1362
Query: 159 AQLEPLQQHLQDSQ---QEISSMQMKLMEMKDLENHNSQL 195
+ + L++H++++ QE S Q + + MK+ +N +++
Sbjct: 1363 VKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKI 1402
Score = 46.2 bits (108), Expect = 8e-05
Identities = 32/160 (20%), Positives = 80/160 (50%), Gaps = 9/160 (5%)
Query: 42 LKEKEDTIKQRTSEVQDLQDE---VQRENTNLQKLQAQKQQVQELLDELDEQKAQLEE-- 96
L E E+ +K+++ ++Q+ Q + VQ E + +QK + +++ L +EL ++ LE
Sbjct: 1122 LAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQK---KINEIENLKNELKNKELTLEHME 1178
Query: 97 -QLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVE 155
+ E+ +K E + + S+ E + ++E E R + ++ + +E ++
Sbjct: 1179 TERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELK 1238
Query: 156 SGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQL 195
L+ Q+ + + ++ +S +++ +DLE +++L
Sbjct: 1239 IAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKL 1278
Score = 46.2 bits (108), Expect = 8e-05
Identities = 43/205 (20%), Positives = 91/205 (44%), Gaps = 5/205 (2%)
Query: 33 REKNNVEQDLKEKEDTIK-QRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQK 91
R DL+ E+T+K +R ++L++ + R+ ++L+ ++E + +D+ +
Sbjct: 1682 RSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLR 1741
Query: 92 AQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELE 151
+ E+ E+ + +LKA+ + ++ L + +E + +L+ +E
Sbjct: 1742 GIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKT 1801
Query: 152 ESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNWCSSPHSILVNGATD 211
+ + + + LE LQ+ QE+ + + +L+ +K N + S L D
Sbjct: 1802 DKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKK---VSEMEQLKKQIKD 1858
Query: 212 YCSLSTSSSETANLNEHVEGQSNLE 236
SL+ S E NLN + NLE
Sbjct: 1859 Q-SLTLSKLEIENLNLAQKLHENLE 1882
Score = 46.2 bits (108), Expect = 8e-05
Identities = 36/167 (21%), Positives = 80/167 (47%), Gaps = 15/167 (8%)
Query: 33 REKNN---VEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQ-KQQVQELLDELD 88
+E++N VE+ LK + D +K+ E + E+Q+E + L + K+ V +L +++
Sbjct: 1889 KERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKIS 1948
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148
E+ Q+ + K++ K K EL + ++ E +L + +E+++ ++
Sbjct: 1949 EKTIQISDIQKDLDKS-----------KDELQKKIQELQKKELQLLRVKEDVNMSHKKIN 1997
Query: 149 ELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQL 195
E+E+ + +AQ +Q D+ Q + L E++ + +L
Sbjct: 1998 EMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDEL 2044
Score = 45.8 bits (107), Expect = 1e-04
Identities = 40/171 (23%), Positives = 84/171 (49%), Gaps = 15/171 (8%)
Query: 29 CWSSREK--NNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQK--QQVQELL 84
C +E+ N + +L EKE I +++ + D++Q + + + + Q +Q+ E+
Sbjct: 1485 CLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQ 1544
Query: 85 DELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQ 144
++++E K Q KE RK Q I S ELT++ + + + K +EE+ R+Q
Sbjct: 1545 EKVNELK-----QFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQ 1599
Query: 145 Q----ETAELEESVESGKAQLEPLQQHLQD--SQQEISSMQMKLMEMKDLE 189
+ E +L+E+ + A+++ Q+ ++ Q K+ E++ L+
Sbjct: 1600 EALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLK 1650
Score = 45.1 bits (105), Expect = 2e-04
Identities = 35/176 (19%), Positives = 88/176 (50%), Gaps = 27/176 (15%)
Query: 38 VEQDLKEKEDTI-------KQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQ 90
V LKE ++TI ++T+E+ ++Q +++ N L+AQ ++QE L
Sbjct: 1726 VHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSN---DALKAQDLKIQEELRIAHMH 1782
Query: 91 KAQLEEQLKEVRKKCAEEAQLISSLKAELTSQES-------QISTYEEELAKAREELSRL 143
+ +E + ++R +E+ +S+++ +L + + ++ E +L +++++
Sbjct: 1783 LKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNET 1842
Query: 144 QQETAELE--------ESVESGKAQLEPLQ--QHLQDSQQEISSMQMKLMEMKDLE 189
Q++ +E+E +S+ K ++E L Q L ++ +E+ S+ + ++ +E
Sbjct: 1843 QKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVE 1898
Score = 44.7 bits (104), Expect = 2e-04
Identities = 33/163 (20%), Positives = 78/163 (47%), Gaps = 12/163 (7%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
REK + + L++ + +K T E DL+ ++Q + LQ ++ Q++ + +
Sbjct: 908 REKTLITEKLQQTLEEVKTLTQEKDDLK-QLQ------ESLQIERDQLKSDIHDTVNMNI 960
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
+EQL+ + + + I++LK++++ + S+ EE + ++E QQ+ +++
Sbjct: 961 DTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDE---FQQKMVGIDK 1017
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQL 195
+ + L ++D+ EI Q K+ + +N Q+
Sbjct: 1018 KQDLEAKNTQTLTADVKDN--EIIEQQRKIFSLIQEKNELQQM 1058
Score = 43.5 bits (101), Expect = 5e-04
Identities = 62/281 (22%), Positives = 122/281 (43%), Gaps = 31/281 (11%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEV--QRENTNLQKLQAQKQQ------------ 79
EK ++ DLKE + + E++ L DE+ Q+E +K A K++
Sbjct: 1065 EKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAE 1124
Query: 80 VQELLDELDEQKAQLEEQLKEVRKKCAE---EAQLISSLKAELTSQESQISTYEEE---- 132
V+E L E +Q + ++QL V+++ +E + I +LK EL ++E + E E
Sbjct: 1125 VEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLEL 1184
Query: 133 ---LAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQ----QEISSMQMKLMEM 185
L + EE+ + +E L+E +S + + + L+ ++++ + Q +++ + +
Sbjct: 1185 AQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHL 1244
Query: 186 KDLENHNSQLNWCSSPHSILVNGATDYCSLSTS-SSETANLNEHVEGQSNLESEPIHQES 244
K+ + +L S + + D T E L+E E N++ QE+
Sbjct: 1245 KEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQET 1304
Query: 245 PARSSPELLPSGVTDENEVTTAVTEKVCSELDNNRHSKEED 285
+ ELL T ++ T A E L+ +E+
Sbjct: 1305 --MNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEE 1343
Score = 43.1 bits (100), Expect = 7e-04
Identities = 36/187 (19%), Positives = 83/187 (44%), Gaps = 33/187 (17%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQ 93
E ++ K K+ ++ S++ +L + +Q +Q + +K++++ + + L ++ Q
Sbjct: 1549 ELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQ 1608
Query: 94 LEEQLKEVRKKCAEEAQL-------------------ISSLKAELTSQESQISTYEEE-- 132
L+E KE+ K E + I LK + +Q+ + E E
Sbjct: 1609 LKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENI 1668
Query: 133 -----LAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDS-------QQEISSMQM 180
L + EE+ + +E +L E+ K + + L+++L+++ Q+E+ + M
Sbjct: 1669 RLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHM 1728
Query: 181 KLMEMKD 187
L E ++
Sbjct: 1729 HLKEHQE 1735
Score = 42.0 bits (97), Expect = 0.002
Identities = 49/202 (24%), Positives = 88/202 (43%), Gaps = 53/202 (26%)
Query: 32 SREKNNVEQDLKEKEDTIKQRTSEVQDLQ-------DEVQRENTNLQKLQAQKQQVQE-- 82
S+E L+EK I ++T ++ D+Q DE+Q++ LQK + Q +V+E
Sbjct: 1933 SKEHKETVDKLREK---ISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDV 1989
Query: 83 -----LLDELDEQKAQLE---------------------EQLKEVRKKCAEEAQLISSLK 116
++E+++ K Q E E L+E+R A+E + +K
Sbjct: 1990 NMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIR-IVAKERDELRRIK 2048
Query: 117 AELTSQESQ-ISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDS-QQE 174
L + Q I+T E +A+ R+ V+ K L QQHL +S +++
Sbjct: 2049 ESLKMERDQFIATLREMIARDRQ------------NHQVKPEKRLLSDGQQHLTESLREK 2096
Query: 175 ISSMQMKLMEMKDLENHNSQLN 196
S ++ L ++++H LN
Sbjct: 2097 CSRIKELLKRYSEMDDHYECLN 2118
Score = 38.9 bits (89), Expect = 0.013
Identities = 56/274 (20%), Positives = 118/274 (43%), Gaps = 28/274 (10%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDL-------QDEVQRENTNLQKLQAQKQQVQELLD 85
+EK+ Q+ +++ +++ SE+Q ++E++ + L+ ++ ++ ++ + L+
Sbjct: 1130 KEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLN 1189
Query: 86 ELDEQKAQLEEQ---LKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSR 142
E E+ + ++ LKE++K E + E+ + Q +EEL A L
Sbjct: 1190 ENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQT---KEELKIAHIHLKE 1246
Query: 143 LQQETAELEESVESGKAQ------LEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLN 196
Q+ EL SV AQ LE LQ+ + Q L +K++ +N
Sbjct: 1247 HQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMN 1306
Query: 197 WCSSPHSILVNGAT--DYCSLSTSSSETANLNEHV-EGQSNLESEPIHQES--PARSSPE 251
+L +T D +L+ E LNE E Q ++S +++ + + E
Sbjct: 1307 ----ELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALE 1362
Query: 252 LLPSGVTDENEVTTAVTEKVCSELDNNRHSKEED 285
+ + + T A ++ S+ + + + KE+D
Sbjct: 1363 VKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKD 1396
Score = 33.9 bits (76), Expect = 0.42
Identities = 34/161 (21%), Positives = 76/161 (47%), Gaps = 19/161 (11%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDE-VQRENTNLQKLQAQKQQVQELLDELDEQKA 92
E+ + ++KE +T ++ +E++ L ++ +++T L +++ ++ ++ E E
Sbjct: 1287 EEQELLPNVKEVSET-QETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQES----- 1340
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTY-EEELAKAREELSRLQQETAELE 151
+E++K + K E + ++K L + Q+ + E LAK +E S+ +Q E
Sbjct: 1341 --QEEIKSLTK----ERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKE 1394
Query: 152 ESVESGK-----AQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
+ E+ K Q +P L + E+ + +L E D
Sbjct: 1395 KDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHD 1435
Score = 30.0 bits (66), Expect = 6.1
Identities = 17/89 (19%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
Query: 41 DLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKE 100
++ E +K+ E+ DL+ +++ + + +K Q+ +LL+E D + E+++
Sbjct: 337 EVSTDEALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIEN 396
Query: 101 VRKKCAEEAQLISSLKAELTSQESQISTY 129
+ + + L +L+ EL ++ + T+
Sbjct: 397 LTRMLVTSSSL--TLQQELKAKRKRRVTW 423
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 69.7 bits (169), Expect = 7e-12
Identities = 41/169 (24%), Positives = 90/169 (53%), Gaps = 8/169 (4%)
Query: 25 SCIVCWSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELL 84
SC+ C S +EK ++++ E + Q + ++ + E +NL+KL+ +++Q+ L
Sbjct: 1780 SCVECLS-KEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQEL 1838
Query: 85 DELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE------ 138
D+L+ K L + ++++ E+ + ++SL+ EL + + ++ +++L +
Sbjct: 1839 DQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLL 1898
Query: 139 -ELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
E +RLQ++ +E E + + E QQ LQ Q EI ++KL++ +
Sbjct: 1899 SEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQE 1947
Score = 62.0 bits (149), Expect = 1e-09
Identities = 44/243 (18%), Positives = 115/243 (47%), Gaps = 20/243 (8%)
Query: 41 DLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKE 100
+L+ + +Q+ E++ + ++R+ ++++ A+ + +Q ++ L ++K L+E+
Sbjct: 1739 ELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDI 1798
Query: 101 VRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQ 160
KK A+ +++++ + ++S + E + K ++EL +L ++ L + +
Sbjct: 1799 WEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISA---- 1854
Query: 161 LEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNWCSSPHSILVNGATDYCSLSTSSS 220
+QQ LQ+ ++ ++S+Q +L ++D N Q ++ H ++ S
Sbjct: 1855 ---MQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVL------------LS 1899
Query: 221 ETANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDENEVTTAVTEKVCSELDNNRH 280
E L + + +N + +E + ++L + + +EN++ E + L R
Sbjct: 1900 EQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEI-EENKLKLVQQEMMFQRLQKERE 1958
Query: 281 SKE 283
S+E
Sbjct: 1959 SEE 1961
Score = 59.3 bits (142), Expect = 9e-09
Identities = 45/218 (20%), Positives = 102/218 (46%), Gaps = 14/218 (6%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQ---DEVQRENTNLQKLQAQKQQVQELLDELDE 89
+E ++E +++++ I + E++DLQ D + ++ ++AQK ++ LD +++
Sbjct: 510 QEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNK 569
Query: 90 QKAQLEEQLKEVRKKCAEEAQLISSLKAELT-----SQESQISTYEEELAKAREELSRLQ 144
Q QLE +L E+ + A+E + I L+ +LT + E+ E ++ +E L ++
Sbjct: 570 QYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIK 629
Query: 145 QETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNWCSSPHSI 204
+ + + + + E L Q L + +QE +++ M+ +++ ++L S
Sbjct: 630 GQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAEL------ESA 683
Query: 205 LVNGATDYCSLSTSSSETANLNEHVEGQSNLESEPIHQ 242
L SL + + + +E + NL +Q
Sbjct: 684 LQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQ 721
Score = 58.2 bits (139), Expect = 2e-08
Identities = 42/162 (25%), Positives = 77/162 (47%), Gaps = 7/162 (4%)
Query: 29 CWSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD 88
C + KN VE+ K + Q S+ ++L+ Q NL K Q + +Q +L+
Sbjct: 1451 CTKEKTKNAVEKFTDAKRSLL-QTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLE 1509
Query: 89 EQKAQLEEQLKEVRKKCA---EEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQ 145
+ K + EE LKE+ K A + Q +S K +LT ++ ++++ A Q
Sbjct: 1510 QHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLT---EELQKLQKDIEMAERNEDHHLQ 1566
Query: 146 ETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
E E +++ +A+LE L+ + QQE++ + +L K+
Sbjct: 1567 VLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKE 1608
Score = 55.5 bits (132), Expect = 1e-07
Identities = 62/278 (22%), Positives = 113/278 (40%), Gaps = 35/278 (12%)
Query: 30 WSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQ----QVQELLD 85
W K E++++E I E + L+ EV+ + +QK Q QK V+ L+
Sbjct: 1344 WMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMT 1403
Query: 86 ELDEQKA-----QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREEL 140
EL+ +K+ + ++++ + K + + L ES++S +E+ A E+
Sbjct: 1404 ELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKF 1463
Query: 141 SRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHN-SQLNWCS 199
+ ++ + E E + + + +L + Q++ S+Q + KDLE H Q
Sbjct: 1464 TDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQ---ADAKDLEQHKIKQEEILK 1520
Query: 200 SPHSILVNGATDYCSLSTSSS-------------ETANLNEHVEGQSNLESEPIHQESPA 246
+ I+ +D+ LS E A NE Q ESE + Q
Sbjct: 1521 EINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAK-- 1578
Query: 247 RSSPELLPSGVTDENEVTTAVTEKVCSELDNNRHSKEE 284
R+ E L S VT + + + ++ H KEE
Sbjct: 1579 RAELEKLKSQVTSQQQEMAVLDRQL-------GHKKEE 1609
Score = 50.8 bits (120), Expect = 3e-06
Identities = 40/172 (23%), Positives = 89/172 (51%), Gaps = 23/172 (13%)
Query: 31 SSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQ----KQQVQELLDE 86
+ R +++ Q LKE E ++ + +E++ L+ +V + + L Q K+++ L
Sbjct: 1557 AERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGS 1616
Query: 87 LDEQKAQLEEQLK----EVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSR 142
+ + KA L+E L+ EV +KC + + SL EL+ Q+ +++ ++++ + +L+
Sbjct: 1617 MVQAKADLQEALRLGETEVTEKC-NHIREVKSLLEELSFQKGELNV---QISERKTQLTL 1672
Query: 143 LQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQ 194
++QE + EE+++ Q+ + L++ +++M LENH Q
Sbjct: 1673 IKQEIEKEEENLQVVLRQMSKHKTELKN-----------ILDMLQLENHELQ 1713
Score = 48.5 bits (114), Expect = 2e-05
Identities = 39/183 (21%), Positives = 85/183 (46%), Gaps = 23/183 (12%)
Query: 32 SREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQ--RENTNLQKLQAQKQQVQELLDELDE 89
+R+K ++ D+ + ++++ V LQ+E+ +++ NL K Q+LL
Sbjct: 1842 NRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAK--------QDLLHTTKH 1893
Query: 90 QKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREEL-------SR 142
Q L EQ + ++K +E A + E +++ Q+ + E+ + + +L R
Sbjct: 1894 QDVLLSEQTR-LQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQR 1952
Query: 143 LQQETAELEESVESGKAQLE----PLQQHLQDSQQEISSMQMKLMEMKD-LENHNSQLNW 197
LQ+E E +E+ K L+ L++ L D + ++ + K++ ++ + + W
Sbjct: 1953 LQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERW 2012
Query: 198 CSS 200
C S
Sbjct: 2013 CES 2015
Score = 48.5 bits (114), Expect = 2e-05
Identities = 39/181 (21%), Positives = 84/181 (46%), Gaps = 18/181 (9%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEV------QRENTNLQKLQAQ-KQQVQELLDE 86
+++ +E++L +++ + Q S+V ++ V +R +L+K +Q K+Q+ E +
Sbjct: 1974 QQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQ 2033
Query: 87 LDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSR---- 142
L E+ +L KE A+ + L + E E Q+++ +E L R +L +
Sbjct: 2034 LVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLE 2093
Query: 143 -------LQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQL 195
+Q+E A +E + + L + L Q E + ++ ++ KDLE ++
Sbjct: 2094 QKQENSCIQKEMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMANQKDLERRQMEI 2153
Query: 196 N 196
+
Sbjct: 2154 S 2154
Score = 47.4 bits (111), Expect = 4e-05
Identities = 36/164 (21%), Positives = 84/164 (51%), Gaps = 11/164 (6%)
Query: 40 QDLKEKEDTIKQRTSEVQDLQDEVQRENTNL--QKLQAQKQQVQELLDE--LDEQKAQLE 95
+D +++E+T +Q ++Q LQ+E++ L Q++ Q+ Q + +E L+ K L+
Sbjct: 1916 EDCQKEEETKQQ---QLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLK 1972
Query: 96 EQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEE---LAKAREELSRLQQETAELEE 152
EQ ++ K+ ++ + + +++ + E ++ T +EE + LS+ +++ +E E+
Sbjct: 1973 EQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQ 2032
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMK-LMEMKDLENHNSQL 195
+ +L LQ+ + + S ++ + L E K E + L
Sbjct: 2033 QLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASL 2076
Score = 44.3 bits (103), Expect = 3e-04
Identities = 38/175 (21%), Positives = 88/175 (50%), Gaps = 11/175 (6%)
Query: 18 VADVLKYSCIVCWSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQK 77
++ + +Y + + + N + L+++++T+ QR +EV+ +E L+ +
Sbjct: 618 ISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVE-------QERDQLEIVAMDA 670
Query: 78 QQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAR 137
+ +++ L EL+ + E +++ + + + L+A L ++++ + +EEL K
Sbjct: 671 ENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKV- 729
Query: 138 EELSRLQQET--AELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLEN 190
L++L+Q AELE+ ++ K L Q ++ +QE S + KL ++D N
Sbjct: 730 TRLTQLEQSALQAELEKERQALKNALGK-AQFSEEKEQENSELHAKLKHLQDDNN 783
Score = 43.1 bits (100), Expect = 7e-04
Identities = 34/150 (22%), Positives = 70/150 (46%), Gaps = 15/150 (10%)
Query: 50 KQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKK----C 105
+Q + +Q +++E+ NL+ ++ + L E DE+K ++ QL+E+ KK
Sbjct: 903 RQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKLED 962
Query: 106 AEEAQLISSLKAELTSQESQISTYEE----ELAKAREELS-------RLQQETAELEESV 154
A+ + + L EL + ++T ++ EL A+++L ++ QE AE +
Sbjct: 963 AKSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQEA 1022
Query: 155 ESGKAQLEPLQQHLQDSQQEISSMQMKLME 184
E + + L ++ EI +Q L +
Sbjct: 1023 ERFSRKAAQAARDLTRAEAEIELLQNLLRQ 1052
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/156 (21%), Positives = 73/156 (46%), Gaps = 22/156 (14%)
Query: 41 DLKEKEDTIKQRTSEVQDLQDEVQR-------ENTNLQKLQAQKQQVQELLDELD----- 88
D ++ E I+Q +E+ LQ+ ++ + LQ+ +K+++ L EL+
Sbjct: 901 DKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKL 960
Query: 89 ------EQKAQLEEQLKEVRKKCAEEAQL----ISSLKAELTSQESQISTYEEELAKARE 138
EQ L+++LK+++K A +L ++ K +L S + +E A+ +
Sbjct: 961 EDAKSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQ 1020
Query: 139 ELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQE 174
E R ++ A+ + +A++E LQ L+ ++
Sbjct: 1021 EAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGEQ 1056
Score = 42.7 bits (99), Expect = 0.001
Identities = 41/158 (25%), Positives = 79/158 (50%), Gaps = 18/158 (11%)
Query: 44 EKEDTIKQRTSEVQ---DLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKE 100
+KE+ + S VQ DLQ+ ++ T + + ++V+ LL+EL QK +L Q+ E
Sbjct: 1606 KKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISE 1665
Query: 101 -------VRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQ----QETAE 149
++++ +E + + + +++ ++++ + L EL L+ Q +E
Sbjct: 1666 RKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSE 1725
Query: 150 LEES---VESGKAQLEPLQQHLQDSQQEISSMQMKLME 184
LE++ V K +LE LQQ Q + EI Q +L+E
Sbjct: 1726 LEKTQVAVLEEKLELENLQQISQQQKGEI-EWQKQLLE 1762
Score = 42.0 bits (97), Expect = 0.002
Identities = 39/192 (20%), Positives = 89/192 (46%), Gaps = 34/192 (17%)
Query: 30 WSSREKNNVEQDLKEK----EDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLD 85
+S E +E+DL++K E+ ++T +++++++ + + ++ QKQ +EL
Sbjct: 267 FSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKS 326
Query: 86 ELDEQKAQLEEQLKEVRKKCAEEAQLISSLK-AELTSQESQISTYEEELA---KAREE-- 139
+L+ + L+++ E+ + C ++ +L L ++ ++ ++ Y E A KA +E
Sbjct: 327 DLNTKNELLKQKTIELTRACQKQYELEQELAFYKIDAKFEPLNYYPSEYAEIDKAPDESP 386
Query: 140 ---------------------LSRLQQETAELEESVESGKAQLE---PLQQHLQDSQQEI 175
+Q + E +E + + L PL L+D +++I
Sbjct: 387 YIGKSRYKRNMFATESYIIDSAQAVQIKKMEPDEQLRNDHMNLRGHTPLDTQLEDKEKKI 446
Query: 176 SSMQMKLMEMKD 187
S+ Q +L E+ D
Sbjct: 447 SAAQTRLSELHD 458
Score = 39.7 bits (91), Expect = 0.008
Identities = 33/144 (22%), Positives = 72/144 (50%), Gaps = 13/144 (9%)
Query: 38 VEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQ 97
+E D + + D + R D Q E + + K+ A + ++ EL DE+++ + Q+
Sbjct: 416 MEPDEQLRNDHMNLRGHTPLDTQLEDKEK-----KISAAQTRLSELHDEIEKAEQQILRA 470
Query: 98 LKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESG 157
+E + QL +++ + S+ + Y++ L+ + +++L+QE +LE +E
Sbjct: 471 TEEFK-------QLEEAIQLKKISEAGKDLLYKQ-LSGRLQLVNKLRQEALDLELQMEKQ 522
Query: 158 KAQLEPLQQHLQDSQQEISSMQMK 181
K ++ Q+ ++D Q I S+ K
Sbjct: 523 KQEIAGKQKEIKDLQIAIDSLDSK 546
Score = 37.0 bits (84), Expect = 0.050
Identities = 38/171 (22%), Positives = 78/171 (45%), Gaps = 26/171 (15%)
Query: 43 KEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVR 102
+EKE + ++++ LQD+ L+ Q V + L +E A+++E ++++
Sbjct: 762 EEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEVAARVDELRRKLK 821
Query: 103 KKCAE-----EAQLISSLKAELTSQESQI---STYEEELAKAREELSRLQQETAELEESV 154
E + ++ A+L Q S+I S +E + A+ RE +LQ+E A +E +
Sbjct: 822 LGTGEMNIHSPSDVLGKSLADLQKQFSEILARSKWERDEAQVRER--KLQEEMALQQEKL 879
Query: 155 ESGKAQLEPL-------------QQH---LQDSQQEISSMQMKLMEMKDLE 189
+G+ + +QH +Q + EI +Q L M++++
Sbjct: 880 ATGQEEFRQACERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQ 930
Score = 36.6 bits (83), Expect = 0.065
Identities = 30/161 (18%), Positives = 71/161 (44%), Gaps = 23/161 (14%)
Query: 49 IKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD-------EQKAQLEEQLKEV 101
++ S ++D+ ++ + + ++A K+Q ++ ++EL ++K LE +++E+
Sbjct: 1321 LENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEEL 1380
Query: 102 RKKCAEEAQL-------ISSLKAELTSQES---------QISTYEEELAKAREELSRLQQ 145
+ + Q + SL EL ++S +I E+ L K R EL +
Sbjct: 1381 HRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADR 1440
Query: 146 ETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
AE E + K + + + D+++ + + E++
Sbjct: 1441 LLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELE 1481
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 68.2 bits (165), Expect = 2e-11
Identities = 35/150 (23%), Positives = 85/150 (56%), Gaps = 4/150 (2%)
Query: 42 LKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEV 101
L+EKE + ++T ++QD+ +E + + L+ + ++ L ++ L+EQL++
Sbjct: 531 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK 590
Query: 102 RKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQ----ETAELEESVESG 157
K+ + + + SL+A+ T+ ++ ++T EE LA+ + RL++ + E +E +++
Sbjct: 591 EKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNY 650
Query: 158 KAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
K L+ L++ + Q ++S + L+++K+
Sbjct: 651 KKDLKDLKEKVSLLQGDLSEKEASLLDLKE 680
Score = 54.3 bits (129), Expect = 3e-07
Identities = 33/151 (21%), Positives = 78/151 (51%), Gaps = 6/151 (3%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
+++N +LK KE K+++++ + +E +R NL QQ+Q+ L + D++
Sbjct: 787 KDQNKKVANLKHKEQVEKKKSAQ---MLEEARRREDNLND---SSQQLQDSLRKKDDRIE 840
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
+LEE L+E + AE +++ ++ T+ E Q+ + K ++EL ++ + + ++
Sbjct: 841 ELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQ 900
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLM 183
S+ + L L+ + +E+ M+ + +
Sbjct: 901 SLAEKETHLTNLRAERRKHLEEVLEMKQEAL 931
Score = 52.4 bits (124), Expect = 1e-06
Identities = 40/182 (21%), Positives = 91/182 (50%), Gaps = 9/182 (4%)
Query: 3 LKSDSGLGGWITIPAVADVLKYSCIVCWSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDE 62
LK DS L T+ + K C+ S +K + E L+ + + + +Q L+ E
Sbjct: 690 LKKDSRLK---TLEIALEQKKEECLKMESQLKKAH-EAALEARASP--EMSDRIQHLERE 743
Query: 63 VQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQ 122
+ R K QA+ ++ E+L E++ +K ++++ E+ ++ ++ + +++LK + +
Sbjct: 744 ITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVE 803
Query: 123 ESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKL 182
+ + + EE AR L + +L++S+ ++E L++ L++S Q + +M L
Sbjct: 804 KKKSAQMLEE---ARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVL 860
Query: 183 ME 184
+
Sbjct: 861 AQ 862
Score = 52.4 bits (124), Expect = 1e-06
Identities = 37/173 (21%), Positives = 88/173 (50%), Gaps = 8/173 (4%)
Query: 20 DVLKYSCIVCWSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKL----QA 75
++ +Y + E + + + LKE E+ + ++ +L+ +V+ +N + L Q
Sbjct: 743 EITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQV 802
Query: 76 QKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAK 135
+K++ ++L+E ++ L + ++++ ++ I L+ L +ES T E E+
Sbjct: 803 EKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEAL--RESVQITAEREMVL 860
Query: 136 AREELSR--LQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
A+EE +R +++ EL ++E K +LE ++ L +QQ ++ + L ++
Sbjct: 861 AQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLR 913
Score = 52.0 bits (123), Expect = 2e-06
Identities = 37/169 (21%), Positives = 85/169 (50%), Gaps = 20/169 (11%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDEL----- 87
R K ++D +EK++ I +++DL+++V +L + +A ++E L
Sbjct: 631 RLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGL 690
Query: 88 --DEQKAQLEEQLKEVRKKC---------AEEAQLISSLKAELTSQ----ESQISTYEEE 132
D + LE L++ +++C A EA L + E++ + E +I+ Y++E
Sbjct: 691 KKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDE 750
Query: 133 LAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMK 181
+KA+ E+ RL + E+E ++ L++ ++D +++++++ K
Sbjct: 751 SSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHK 799
Score = 48.5 bits (114), Expect = 2e-05
Identities = 51/273 (18%), Positives = 115/273 (42%), Gaps = 39/273 (14%)
Query: 42 LKEKEDTIKQRTSEVQDLQDEVQRENTN--------------LQKLQAQKQQVQELLDEL 87
++ K+ I ++DL++E+Q +N ++ ++ + ++ +++L
Sbjct: 384 IEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQL 443
Query: 88 DEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQET 147
E+ + E Q +E++KK A L+AE+ + ++S + EL + +L L +
Sbjct: 444 KEELSSKEAQWEELKKKAA-------GLQAEIGQVKQELSRKDTELLALQTKLETLTNQF 496
Query: 148 AELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNS-QLNWCSSPHSILV 206
++ ++ +E K L +Q Q E+ +++++L E + + N + Q+ +
Sbjct: 497 SDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQA 556
Query: 207 NGATDYCSLSTSSSETAN-LNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDENEVTT 265
D + N L + +E NL+ + +E S E + S D T
Sbjct: 557 GEIHDLKDMLDVKERKVNVLQKKIE---NLQEQLRDKEKQMSSLKERVKSLQADTTNTDT 613
Query: 266 AVT-------------EKVCSELDNNRHSKEED 285
A+T E++ + D + K+E+
Sbjct: 614 ALTTLEEALAEKERTIERLKEQRDRDEREKQEE 646
Score = 47.4 bits (111), Expect = 4e-05
Identities = 33/174 (18%), Positives = 90/174 (51%), Gaps = 21/174 (12%)
Query: 36 NNVEQDLKEKEDTIKQRTSE----VQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQK 91
+++E+ L++ E+ I+ S ++ ++E+++ + K +V++L +EL ++
Sbjct: 392 SSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKE 451
Query: 92 AQLEE----------QLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELS 141
AQ EE ++ +V+++ + + + +L+ +L + +Q S ++ + +E L+
Sbjct: 452 AQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLT 511
Query: 142 RLQQETAELEESVESGKAQLEPLQ-------QHLQDSQQEISSMQMKLMEMKDL 188
+Q A L+ V++ + +LE + + +QD +E + ++ ++KD+
Sbjct: 512 AKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDM 565
Score = 45.1 bits (105), Expect = 2e-04
Identities = 31/154 (20%), Positives = 79/154 (51%), Gaps = 14/154 (9%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
R ++N+ ++ +D+++++ +++L+ E RE+ ++ A+++ V L + + +
Sbjct: 816 RREDNLNDSSQQLQDSLRKKDDRIEELE-EALRESV---QITAEREMV---LAQEESART 868
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAR-------EELSRLQQ 145
E+Q++E+ + Q + S+KA+L+S + ++ E L R EE+ ++Q
Sbjct: 869 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQ 928
Query: 146 ETAELEESVESGKAQLEPLQQHLQDSQQEISSMQ 179
E S + L L + +Q+E+++++
Sbjct: 929 EALLAAISEKDANIALLELSSSKKKTQEEVAALK 962
Score = 44.7 bits (104), Expect = 2e-04
Identities = 33/166 (19%), Positives = 75/166 (45%), Gaps = 17/166 (10%)
Query: 38 VEQDLKEKEDTIK----QRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQ 93
+E+ L EKE TI+ QR + ++ Q+E+ +L+ L+ + +Q L E +
Sbjct: 618 LEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLD 677
Query: 94 LEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE-------------EL 140
L+E + ++ + +L+ L ++ + E +L KA E +
Sbjct: 678 LKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRI 737
Query: 141 SRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
L++E ++ +A+++ L + L++ + E + K+ E++
Sbjct: 738 QHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELE 783
Score = 43.1 bits (100), Expect = 7e-04
Identities = 33/161 (20%), Positives = 75/161 (46%), Gaps = 14/161 (8%)
Query: 39 EQDLKEKEDTIKQRTSEVQD------LQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
+Q L ++++IK+ +Q +E L + + ++ LL++ +++ +
Sbjct: 299 KQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENS 358
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
L E++ R + A ++ +L+ + ++S+IS+ E L EE+ L+ A E
Sbjct: 359 MLREEMHR-RFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTE 417
Query: 153 SVESGKAQLEPLQQH-------LQDSQQEISSMQMKLMEMK 186
E Q+E + H ++ ++E+SS + + E+K
Sbjct: 418 EREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELK 458
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 68.2 bits (165), Expect = 2e-11
Identities = 35/150 (23%), Positives = 85/150 (56%), Gaps = 4/150 (2%)
Query: 42 LKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEV 101
L+EKE + ++T ++QD+ +E + + L+ + ++ L ++ L+EQL++
Sbjct: 503 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK 562
Query: 102 RKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQ----ETAELEESVESG 157
K+ + + + SL+A+ T+ ++ ++T EE LA+ + RL++ + E +E +++
Sbjct: 563 EKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNY 622
Query: 158 KAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
K L+ L++ + Q ++S + L+++K+
Sbjct: 623 KKDLKDLKEKVSLLQGDLSEKEASLLDLKE 652
Score = 54.3 bits (129), Expect = 3e-07
Identities = 33/151 (21%), Positives = 78/151 (51%), Gaps = 6/151 (3%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
+++N +LK KE K+++++ + +E +R NL QQ+Q+ L + D++
Sbjct: 759 KDQNKKVANLKHKEQVEKKKSAQ---MLEEARRREDNLND---SSQQLQDSLRKKDDRIE 812
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
+LEE L+E + AE +++ ++ T+ E Q+ + K ++EL ++ + + ++
Sbjct: 813 ELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQ 872
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLM 183
S+ + L L+ + +E+ M+ + +
Sbjct: 873 SLAEKETHLTNLRAERRKHLEEVLEMKQEAL 903
Score = 52.4 bits (124), Expect = 1e-06
Identities = 40/182 (21%), Positives = 91/182 (50%), Gaps = 9/182 (4%)
Query: 3 LKSDSGLGGWITIPAVADVLKYSCIVCWSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDE 62
LK DS L T+ + K C+ S +K + E L+ + + + +Q L+ E
Sbjct: 662 LKKDSRLK---TLEIALEQKKEECLKMESQLKKAH-EAALEARASP--EMSDRIQHLERE 715
Query: 63 VQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQ 122
+ R K QA+ ++ E+L E++ +K ++++ E+ ++ ++ + +++LK + +
Sbjct: 716 ITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVE 775
Query: 123 ESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKL 182
+ + + EE AR L + +L++S+ ++E L++ L++S Q + +M L
Sbjct: 776 KKKSAQMLEE---ARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVL 832
Query: 183 ME 184
+
Sbjct: 833 AQ 834
Score = 52.4 bits (124), Expect = 1e-06
Identities = 37/173 (21%), Positives = 88/173 (50%), Gaps = 8/173 (4%)
Query: 20 DVLKYSCIVCWSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKL----QA 75
++ +Y + E + + + LKE E+ + ++ +L+ +V+ +N + L Q
Sbjct: 715 EITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQV 774
Query: 76 QKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAK 135
+K++ ++L+E ++ L + ++++ ++ I L+ L +ES T E E+
Sbjct: 775 EKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEAL--RESVQITAEREMVL 832
Query: 136 AREELSR--LQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
A+EE +R +++ EL ++E K +LE ++ L +QQ ++ + L ++
Sbjct: 833 AQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLR 885
Score = 52.0 bits (123), Expect = 2e-06
Identities = 37/169 (21%), Positives = 85/169 (50%), Gaps = 20/169 (11%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDEL----- 87
R K ++D +EK++ I +++DL+++V +L + +A ++E L
Sbjct: 603 RLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGL 662
Query: 88 --DEQKAQLEEQLKEVRKKC---------AEEAQLISSLKAELTSQ----ESQISTYEEE 132
D + LE L++ +++C A EA L + E++ + E +I+ Y++E
Sbjct: 663 KKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDE 722
Query: 133 LAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMK 181
+KA+ E+ RL + E+E ++ L++ ++D +++++++ K
Sbjct: 723 SSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHK 771
Score = 46.6 bits (109), Expect = 6e-05
Identities = 40/170 (23%), Positives = 86/170 (50%), Gaps = 16/170 (9%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQ--K 91
++ + E + + KE + ++T E +L+ E Q+ Q L A+ + +++LL+ L +
Sbjct: 268 QRLHAEHERQAKELFLLRKTLEEMELRIETQK-----QTLNARDESIKKLLEMLQSKGLS 322
Query: 92 AQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELE 151
A+ E+ E ++ AE + L++ L +E + S EE+ + R E + +T L+
Sbjct: 323 AKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEMHR-RFENAPDSAKTKALQ 381
Query: 152 ESVESGKAQLEPLQQHLQDSQQEIS--------SMQMKLMEMKDLENHNS 193
+E +++ +++ L+D ++EI S + + EMK +E + S
Sbjct: 382 TVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRS 431
Score = 45.1 bits (105), Expect = 2e-04
Identities = 31/154 (20%), Positives = 79/154 (51%), Gaps = 14/154 (9%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
R ++N+ ++ +D+++++ +++L+ E RE+ ++ A+++ V L + + +
Sbjct: 788 RREDNLNDSSQQLQDSLRKKDDRIEELE-EALRESV---QITAEREMV---LAQEESART 840
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAR-------EELSRLQQ 145
E+Q++E+ + Q + S+KA+L+S + ++ E L R EE+ ++Q
Sbjct: 841 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQ 900
Query: 146 ETAELEESVESGKAQLEPLQQHLQDSQQEISSMQ 179
E S + L L + +Q+E+++++
Sbjct: 901 EALLAAISEKDANIALLELSSSKKKTQEEVAALK 934
Score = 44.7 bits (104), Expect = 2e-04
Identities = 33/166 (19%), Positives = 75/166 (45%), Gaps = 17/166 (10%)
Query: 38 VEQDLKEKEDTIK----QRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQ 93
+E+ L EKE TI+ QR + ++ Q+E+ +L+ L+ + +Q L E +
Sbjct: 590 LEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLD 649
Query: 94 LEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE-------------EL 140
L+E + ++ + +L+ L ++ + E +L KA E +
Sbjct: 650 LKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRI 709
Query: 141 SRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
L++E ++ +A+++ L + L++ + E + K+ E++
Sbjct: 710 QHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELE 755
Score = 43.1 bits (100), Expect = 7e-04
Identities = 25/154 (16%), Positives = 78/154 (50%), Gaps = 7/154 (4%)
Query: 42 LKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEV 101
++ K+ I ++DL++E+Q +N ++++ + ++ ++ ++ +V
Sbjct: 384 IEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQV 443
Query: 102 RKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQL 161
+++ + + + +L+ +L + +Q S ++ + +E L+ +Q A L+ V++ + +L
Sbjct: 444 KQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRL 503
Query: 162 EPLQ-------QHLQDSQQEISSMQMKLMEMKDL 188
E + + +QD +E + ++ ++KD+
Sbjct: 504 EEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDM 537
Score = 41.2 bits (95), Expect = 0.003
Identities = 58/294 (19%), Positives = 119/294 (40%), Gaps = 48/294 (16%)
Query: 32 SREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQK 91
+R E + E ++Q+ E L++E+ R N A+ + +Q +++ D +
Sbjct: 333 TRRLAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPD-SAKTKALQTVIEMKDSKI 391
Query: 92 AQLEEQLKEVRKKCAEEAQLISSLKAELTSQES----QISTY-------EEELAKAREEL 140
+ +E L+++ EE Q++ S A T + Q+ Y + ++ + ++EL
Sbjct: 392 SSMERGLRDLE----EEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQEL 447
Query: 141 SRLQQETAELEESVESGKAQLEPLQQH---LQDS-----------QQEISSMQMKLMEMK 186
SR E L+ +E+ Q +QH L++S Q E+ +++++L E +
Sbjct: 448 SRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKE 507
Query: 187 DLENHNS-QLNWCSSPHSILVNGATDYCSLSTSSSETAN-LNEHVEGQSNLESEPIHQES 244
+ N + Q+ + D + N L + +E NL+ + +E
Sbjct: 508 TMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIE---NLQEQLRDKEK 564
Query: 245 PARSSPELLPSGVTDENEVTTAVT-------------EKVCSELDNNRHSKEED 285
S E + S D TA+T E++ + D + K+E+
Sbjct: 565 QMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEE 618
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 65.1 bits (157), Expect = 2e-10
Identities = 25/168 (14%), Positives = 92/168 (54%), Gaps = 1/168 (0%)
Query: 30 WSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDE 89
W +EK + ++ ++++E+ + ++ ++ D +++++ + + + + + ++ +E + E +E
Sbjct: 478 WRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEE 537
Query: 90 QKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAE 149
+ + EE ++E +K E+ + + + ++ QE +I EE++ + +E++ +++ E
Sbjct: 538 KIREQEEMMQEQEEKMGEQEEKMQE-QEKMRRQEEKIREQEEKIREQKEKIREQEEKIWE 596
Query: 150 LEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 197
EE + + ++ ++ + + ++++ + K+ E ++ + W
Sbjct: 597 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 644
Score = 62.4 bits (150), Expect = 1e-09
Identities = 29/168 (17%), Positives = 95/168 (56%), Gaps = 3/168 (1%)
Query: 30 WSSREK-NNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD 88
W EK ++ E+ ++E+E+ + ++ ++++ +++++ + +++ + Q+ +E + E
Sbjct: 498 WRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGE-Q 556
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148
E+K Q +E+++ +K E+ + I K ++ QE +I EE++ + E + +++
Sbjct: 557 EEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMW 616
Query: 149 ELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD-LENHNSQL 195
E EE + + +++ ++ ++ ++++ +++L + ++ ++ H L
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
Score = 62.0 bits (149), Expect = 1e-09
Identities = 31/147 (21%), Positives = 86/147 (58%), Gaps = 7/147 (4%)
Query: 30 WSSREK-NNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQ---KLQAQKQQVQELLD 85
W EK E+ ++E+E+ I+++ +Q+ ++++ + +Q K++ Q+++++E +
Sbjct: 519 WRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEE 578
Query: 86 ELDEQKAQL---EEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSR 142
++ EQK ++ EE++ E +K E+ +++ + ++ QE ++ EE++ + E++ R
Sbjct: 579 KIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 638
Query: 143 LQQETAELEESVESGKAQLEPLQQHLQ 169
+++ E E + + +++ Q+HL+
Sbjct: 639 QEEKMWEQEVRLRQQEEKMQEHQEHLE 665
Score = 56.2 bits (134), Expect = 8e-08
Identities = 33/178 (18%), Positives = 90/178 (50%), Gaps = 11/178 (6%)
Query: 30 WSSREKNNVEQDLKEKEDTIKQ----RTSEVQDLQDEVQRENTNL---QKLQAQKQQV-- 80
W EK + ++ ++E+E +Q R E Q+E+ R+ + +K++ Q+++V
Sbjct: 440 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWR 499
Query: 81 -QELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREE 139
+E + + +E+ + EE++ +K E+ + I + ++ QE + EE++ + E+
Sbjct: 500 QEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK 559
Query: 140 LSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 197
+ Q++ EE + + ++ ++ +++ +++I + K+ E +++ + W
Sbjct: 560 MQE-QEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMW 616
Score = 50.4 bits (119), Expect = 4e-06
Identities = 31/158 (19%), Positives = 80/158 (50%), Gaps = 4/158 (2%)
Query: 43 KEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVR 102
K+ + I++ T E L E+ R ++L+ + ++QE L ++ +K++++ +KE++
Sbjct: 189 KKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELK 248
Query: 103 KKCAEEAQLI---SSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKA 159
+K E A+L+ L+AE ++ + +L EE + + EE + +
Sbjct: 249 RK-LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE 307
Query: 160 QLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 197
+++ ++ +Q+ +++I + K+ E ++ ++ W
Sbjct: 308 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345
Score = 50.4 bits (119), Expect = 4e-06
Identities = 26/157 (16%), Positives = 84/157 (53%), Gaps = 5/157 (3%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E+ ++E+E+ I+++ ++ ++++ + + + +K+Q QE + +E+ + EE
Sbjct: 422 EEKIREQEEKIREQEKKMWRQEEKIHEQE---KIREEEKRQEQEEMWRQEEKIREQEEIW 478
Query: 99 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 158
++ K+ E + I + ++ QE ++ EE++ + E++ R +++ E EE + +
Sbjct: 479 RQ--KEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQE 536
Query: 159 AQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQL 195
++ ++ +Q+ ++++ + K+ E + + ++
Sbjct: 537 EKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKI 573
Score = 48.9 bits (115), Expect = 1e-05
Identities = 26/160 (16%), Positives = 88/160 (55%), Gaps = 3/160 (1%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E+ ++E+E+ ++++ + + +++++R+ + + + + ++++E++ E +E+ +LEE++
Sbjct: 327 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKM 386
Query: 99 KEVRK--KCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVES 156
E K + E+ Q ++ + QE + + +E K RE+ +++++ ++ E
Sbjct: 387 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE-EKIREQEEKIREQEKKMWRQEEK 445
Query: 157 GKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLN 196
Q + ++ + Q+E+ + K+ E +++ +++
Sbjct: 446 IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMH 485
Score = 48.5 bits (114), Expect = 2e-05
Identities = 36/167 (21%), Positives = 84/167 (50%), Gaps = 10/167 (5%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEV--QDLQDEVQRENTNLQ----KLQAQKQQVQELLDEL 87
EK+ ++ ++KE + +++ + Q LQ E LQ KLQAQ ++ EL + L
Sbjct: 236 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE-NELWNRL 294
Query: 88 DEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQET 147
++Q+ EE++ +K E + I + ++ QE +I EE++ + E + +++
Sbjct: 295 NQQQ---EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 351
Query: 148 AELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQ 194
EE + + ++ L++ + + +++I ++ K+ E + + +
Sbjct: 352 RRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK 398
Score = 45.8 bits (107), Expect = 1e-04
Identities = 30/160 (18%), Positives = 84/160 (52%), Gaps = 20/160 (12%)
Query: 30 WSSREK-NNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD 88
W EK E+ ++E+E+ I+++ ++++ +++++R+ + + + + ++ +E++ E +
Sbjct: 303 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 362
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148
E+ +LEE + E +K E L+ ++ QE K RE+ + Q+E
Sbjct: 363 EKMRRLEEMMWEKEEKIRE-------LEEKMHEQE-----------KIREQEEKRQEEEK 404
Query: 149 ELE-ESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
E E + +A++ ++ +++ +++I + K+ ++
Sbjct: 405 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE 444
Score = 42.7 bits (99), Expect = 0.001
Identities = 35/144 (24%), Positives = 67/144 (46%), Gaps = 6/144 (4%)
Query: 46 EDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKC 105
ED K + L+ E++ + ++ L QK ++Q L QLE + +++ +
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 106 AEEAQLISSLKAELTS---QESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLE 162
+ + L+ L++ Q+ + Y EEL K R+ LS +E ++ A+L
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL- 226
Query: 163 PLQQHLQDSQQEISSMQMKLMEMK 186
Q+ LQ + E S +Q+ + E+K
Sbjct: 227 --QEKLQLVESEKSEIQLNVKELK 248
Score = 42.7 bits (99), Expect = 0.001
Identities = 37/175 (21%), Positives = 86/175 (49%), Gaps = 27/175 (15%)
Query: 30 WSSREK-NNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD 88
W EK +E+ + EKE+ I++ ++ + Q++++ Q +K+Q +E + E +
Sbjct: 359 WEKEEKMRRLEEMMWEKEEKIRELEEKMHE-QEKIRE--------QEEKRQEEEKIREQE 409
Query: 89 ---EQKAQL----------EEQLKEVRKKCAEEAQLI---SSLKAELTSQESQISTYEEE 132
EQ+A++ EE+++E KK + + I ++ E QE + +EE
Sbjct: 410 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 469
Query: 133 LAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
+ +EE+ R Q+E +E + + ++ ++ + D +++I + K+ ++
Sbjct: 470 KIREQEEIWR-QKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEE 523
Score = 42.0 bits (97), Expect = 0.002
Identities = 19/123 (15%), Positives = 72/123 (58%), Gaps = 7/123 (5%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQ 93
EK +++ ++++ ++++ ++++ +++++ + +K++ Q++++ E +++ EQ+
Sbjct: 551 EKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK---EKIREQEEKIWEQEEKIREQEEM 607
Query: 94 LEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEES 153
++EQ +K E+ + + + ++ QE ++ EE++ + L + +++ E +E
Sbjct: 608 MQEQ----EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEH 663
Query: 154 VES 156
+E+
Sbjct: 664 LEA 666
Score = 38.1 bits (87), Expect = 0.022
Identities = 40/183 (21%), Positives = 87/183 (47%), Gaps = 19/183 (10%)
Query: 31 SSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQ 90
S + + + ++L+ + TI+ T + +LQ + +++L+ + + + L + +
Sbjct: 114 SHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKF 173
Query: 91 KAQLEEQLKEV---RKKCAEEAQLISSLKAELTSQESQISTYEEEL----AKAREELSRL 143
+LE+ L V +KK + ++ + L+ + + + +EEL AK +E+L +
Sbjct: 174 AGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLV 233
Query: 144 QQETAELEESVESGKAQLE------PLQQ------HLQDSQQEISSMQMKLMEMKDLENH 191
+ E +E++ +V+ K +LE P QQ HL Q +S+ +E +L N
Sbjct: 234 ESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR 293
Query: 192 NSQ 194
+Q
Sbjct: 294 LNQ 296
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 65.1 bits (157), Expect = 2e-10
Identities = 47/158 (29%), Positives = 86/158 (54%), Gaps = 14/158 (8%)
Query: 40 QDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLK 99
+DL+EK +T++ + +E + E L+K + Q +QVQE ++ EQ+A L+ +LK
Sbjct: 91 RDLEEKLETLRLKRAEDKAKLKE-------LEKHKIQLEQVQEWKSKMQEQQADLQRRLK 143
Query: 100 EVRKKCAEEAQLISSLKAEL--TSQESQISTYEEELAKAREELSRLQQETAELEESVESG 157
E RK+ E + E+ T+ +++T ++E+A+ R E LQQE L+E V+
Sbjct: 144 EARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAE--SLQQEVEALKERVDEL 201
Query: 158 KAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQL 195
LE L+ +++ + ++ +L K LE N++L
Sbjct: 202 TTDLEILKAEIEEKGSDGAASSYQL---KQLEEQNARL 236
Score = 50.8 bits (120), Expect = 3e-06
Identities = 30/155 (19%), Positives = 77/155 (49%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
R ++ KE + ++ E+ D D ++ + + + + + +Q+ ++ L E+
Sbjct: 140 RRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVD 199
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
+L L+ ++ + E+ ++ +L E Q + ++ L + R+ S +QE +L++
Sbjct: 200 ELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQK 259
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
+E +LE ++Q + Q+E+S + + E+K+
Sbjct: 260 LMEKKNQELEVVRQQRERLQEELSQAESTIDELKE 294
Score = 47.8 bits (112), Expect = 3e-05
Identities = 45/178 (25%), Positives = 81/178 (45%), Gaps = 24/178 (13%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEE-- 96
E+ ++E DT D + +R + Q+++A K++V EL +L+ KA++EE
Sbjct: 157 ERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKG 216
Query: 97 --------QLKEVRKKCAE-------EAQLISSLKAELTSQESQISTYEEELAKAREELS 141
QLK++ ++ A L SS K E + + +EL R++
Sbjct: 217 SDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRE 276
Query: 142 RLQQETAELEESVESGKAQL------EPLQQHLQDSQQEISSMQMKLME-MKDLENHN 192
RLQ+E ++ E +++ K Q+ E + + L D + +L E + DLE N
Sbjct: 277 RLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMN 334
Score = 43.1 bits (100), Expect = 7e-04
Identities = 36/201 (17%), Positives = 91/201 (45%), Gaps = 18/201 (8%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEV------QDLQDEVQRENTNLQKLQAQKQQVQELLDE 86
+++ ++++L + E TI + +V +++ + + N NL++ + ++ L+
Sbjct: 273 QQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEA 332
Query: 87 LDEQKAQLEEQLKEVRKKCAEEAQL----ISSLKAELTSQESQISTYEEELAKAREELSR 142
++E +L+E +E + E+ + + + + + + ++ Y++ + K R+ +
Sbjct: 333 MNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAH 392
Query: 143 LQQETAELEESVE-SGKAQLEP------LQQHLQDSQQEISSMQMKLMEMKDLE-NHNSQ 194
LQ EL E S + Q +P + +++ +++M+L +M+ + N +
Sbjct: 393 LQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMS 452
Query: 195 LNWCSSPHSILVNGATDYCSL 215
L P S L G C L
Sbjct: 453 LLTAFMPDSFLRPGGDHDCVL 473
Score = 34.7 bits (78), Expect = 0.25
Identities = 26/109 (23%), Positives = 53/109 (48%), Gaps = 8/109 (7%)
Query: 42 LKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDE-LDEQKAQLEEQLKE 100
L+++E IK+ ++ +E+ N L L+ + + DE +++ + +LEE
Sbjct: 811 LEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQAL 870
Query: 101 VRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAE 149
+RKK E + + +L+A+ I E E A+ ++ L+ + T E
Sbjct: 871 LRKKEKEFEETMDALQAD-------IDQLEAEKAELKQRLNSQSKRTIE 912
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 65.1 bits (157), Expect = 2e-10
Identities = 47/158 (29%), Positives = 86/158 (54%), Gaps = 14/158 (8%)
Query: 40 QDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLK 99
+DL+EK +T++ + +E + E L+K + Q +QVQE ++ EQ+A L+ +LK
Sbjct: 205 RDLEEKLETLRLKRAEDKAKLKE-------LEKHKIQLEQVQEWKSKMQEQQADLQRRLK 257
Query: 100 EVRKKCAEEAQLISSLKAEL--TSQESQISTYEEELAKAREELSRLQQETAELEESVESG 157
E RK+ E + E+ T+ +++T ++E+A+ R E LQQE L+E V+
Sbjct: 258 EARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAE--SLQQEVEALKERVDEL 315
Query: 158 KAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQL 195
LE L+ +++ + ++ +L K LE N++L
Sbjct: 316 TTDLEILKAEIEEKGSDGAASSYQL---KQLEEQNARL 350
Score = 50.8 bits (120), Expect = 3e-06
Identities = 30/155 (19%), Positives = 77/155 (49%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
R ++ KE + ++ E+ D D ++ + + + + + +Q+ ++ L E+
Sbjct: 254 RRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVD 313
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
+L L+ ++ + E+ ++ +L E Q + ++ L + R+ S +QE +L++
Sbjct: 314 ELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQK 373
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
+E +LE ++Q + Q+E+S + + E+K+
Sbjct: 374 LMEKKNQELEVVRQQRERLQEELSQAESTIDELKE 408
Score = 47.8 bits (112), Expect = 3e-05
Identities = 45/178 (25%), Positives = 81/178 (45%), Gaps = 24/178 (13%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEE-- 96
E+ ++E DT D + +R + Q+++A K++V EL +L+ KA++EE
Sbjct: 271 ERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKG 330
Query: 97 --------QLKEVRKKCAE-------EAQLISSLKAELTSQESQISTYEEELAKAREELS 141
QLK++ ++ A L SS K E + + +EL R++
Sbjct: 331 SDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRE 390
Query: 142 RLQQETAELEESVESGKAQL------EPLQQHLQDSQQEISSMQMKLME-MKDLENHN 192
RLQ+E ++ E +++ K Q+ E + + L D + +L E + DLE N
Sbjct: 391 RLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMN 448
Score = 43.1 bits (100), Expect = 7e-04
Identities = 36/201 (17%), Positives = 91/201 (45%), Gaps = 18/201 (8%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEV------QDLQDEVQRENTNLQKLQAQKQQVQELLDE 86
+++ ++++L + E TI + +V +++ + + N NL++ + ++ L+
Sbjct: 387 QQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEA 446
Query: 87 LDEQKAQLEEQLKEVRKKCAEEAQL----ISSLKAELTSQESQISTYEEELAKAREELSR 142
++E +L+E +E + E+ + + + + + + ++ Y++ + K R+ +
Sbjct: 447 MNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAH 506
Query: 143 LQQETAELEESVE-SGKAQLEP------LQQHLQDSQQEISSMQMKLMEMKDLE-NHNSQ 194
LQ EL E S + Q +P + +++ +++M+L +M+ + N +
Sbjct: 507 LQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMS 566
Query: 195 LNWCSSPHSILVNGATDYCSL 215
L P S L G C L
Sbjct: 567 LLTAFMPDSFLRPGGDHDCVL 587
Score = 34.7 bits (78), Expect = 0.25
Identities = 26/109 (23%), Positives = 53/109 (48%), Gaps = 8/109 (7%)
Query: 42 LKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDE-LDEQKAQLEEQLKE 100
L+++E IK+ ++ +E+ N L L+ + + DE +++ + +LEE
Sbjct: 925 LEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQAL 984
Query: 101 VRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAE 149
+RKK E + + +L+A+ I E E A+ ++ L+ + T E
Sbjct: 985 LRKKEKEFEETMDALQAD-------IDQLEAEKAELKQRLNSQSKRTIE 1026
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 65.1 bits (157), Expect = 2e-10
Identities = 47/158 (29%), Positives = 86/158 (54%), Gaps = 14/158 (8%)
Query: 40 QDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLK 99
+DL+EK +T++ + +E + E L+K + Q +QVQE ++ EQ+A L+ +LK
Sbjct: 91 RDLEEKLETLRLKRAEDKAKLKE-------LEKHKIQLEQVQEWKSKMQEQQADLQRRLK 143
Query: 100 EVRKKCAEEAQLISSLKAEL--TSQESQISTYEEELAKAREELSRLQQETAELEESVESG 157
E RK+ E + E+ T+ +++T ++E+A+ R E LQQE L+E V+
Sbjct: 144 EARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAE--SLQQEVEALKERVDEL 201
Query: 158 KAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQL 195
LE L+ +++ + ++ +L K LE N++L
Sbjct: 202 TTDLEILKAEIEEKGSDGAASSYQL---KQLEEQNARL 236
Score = 50.8 bits (120), Expect = 3e-06
Identities = 30/155 (19%), Positives = 77/155 (49%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
R ++ KE + ++ E+ D D ++ + + + + + +Q+ ++ L E+
Sbjct: 140 RRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVD 199
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
+L L+ ++ + E+ ++ +L E Q + ++ L + R+ S +QE +L++
Sbjct: 200 ELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQK 259
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
+E +LE ++Q + Q+E+S + + E+K+
Sbjct: 260 LMEKKNQELEVVRQQRERLQEELSQAESTIDELKE 294
Score = 47.8 bits (112), Expect = 3e-05
Identities = 45/178 (25%), Positives = 81/178 (45%), Gaps = 24/178 (13%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEE-- 96
E+ ++E DT D + +R + Q+++A K++V EL +L+ KA++EE
Sbjct: 157 ERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKG 216
Query: 97 --------QLKEVRKKCAE-------EAQLISSLKAELTSQESQISTYEEELAKAREELS 141
QLK++ ++ A L SS K E + + +EL R++
Sbjct: 217 SDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRE 276
Query: 142 RLQQETAELEESVESGKAQL------EPLQQHLQDSQQEISSMQMKLME-MKDLENHN 192
RLQ+E ++ E +++ K Q+ E + + L D + +L E + DLE N
Sbjct: 277 RLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMN 334
Score = 43.1 bits (100), Expect = 7e-04
Identities = 36/201 (17%), Positives = 91/201 (45%), Gaps = 18/201 (8%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEV------QDLQDEVQRENTNLQKLQAQKQQVQELLDE 86
+++ ++++L + E TI + +V +++ + + N NL++ + ++ L+
Sbjct: 273 QQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEA 332
Query: 87 LDEQKAQLEEQLKEVRKKCAEEAQL----ISSLKAELTSQESQISTYEEELAKAREELSR 142
++E +L+E +E + E+ + + + + + + ++ Y++ + K R+ +
Sbjct: 333 MNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAH 392
Query: 143 LQQETAELEESVE-SGKAQLEP------LQQHLQDSQQEISSMQMKLMEMKDLE-NHNSQ 194
LQ EL E S + Q +P + +++ +++M+L +M+ + N +
Sbjct: 393 LQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMS 452
Query: 195 LNWCSSPHSILVNGATDYCSL 215
L P S L G C L
Sbjct: 453 LLTAFMPDSFLRPGGDHDCVL 473
Score = 34.7 bits (78), Expect = 0.25
Identities = 26/109 (23%), Positives = 53/109 (48%), Gaps = 8/109 (7%)
Query: 42 LKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDE-LDEQKAQLEEQLKE 100
L+++E IK+ ++ +E+ N L L+ + + DE +++ + +LEE
Sbjct: 811 LEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQAL 870
Query: 101 VRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAE 149
+RKK E + + +L+A+ I E E A+ ++ L+ + T E
Sbjct: 871 LRKKEKEFEETMDALQAD-------IDQLEAEKAELKQRLNSQSKRTIE 912
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 65.1 bits (157), Expect = 2e-10
Identities = 47/158 (29%), Positives = 86/158 (54%), Gaps = 14/158 (8%)
Query: 40 QDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLK 99
+DL+EK +T++ + +E + E L+K + Q +QVQE ++ EQ+A L+ +LK
Sbjct: 225 RDLEEKLETLRLKRAEDKAKLKE-------LEKHKIQLEQVQEWKSKMQEQQADLQRRLK 277
Query: 100 EVRKKCAEEAQLISSLKAEL--TSQESQISTYEEELAKAREELSRLQQETAELEESVESG 157
E RK+ E + E+ T+ +++T ++E+A+ R E LQQE L+E V+
Sbjct: 278 EARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAE--SLQQEVEALKERVDEL 335
Query: 158 KAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQL 195
LE L+ +++ + ++ +L K LE N++L
Sbjct: 336 TTDLEILKAEIEEKGSDGAASSYQL---KQLEEQNARL 370
Score = 50.8 bits (120), Expect = 3e-06
Identities = 30/155 (19%), Positives = 77/155 (49%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
R ++ KE + ++ E+ D D ++ + + + + + +Q+ ++ L E+
Sbjct: 274 RRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVD 333
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
+L L+ ++ + E+ ++ +L E Q + ++ L + R+ S +QE +L++
Sbjct: 334 ELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQK 393
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
+E +LE ++Q + Q+E+S + + E+K+
Sbjct: 394 LMEKKNQELEVVRQQRERLQEELSQAESTIDELKE 428
Score = 47.8 bits (112), Expect = 3e-05
Identities = 45/178 (25%), Positives = 81/178 (45%), Gaps = 24/178 (13%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEE-- 96
E+ ++E DT D + +R + Q+++A K++V EL +L+ KA++EE
Sbjct: 291 ERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKG 350
Query: 97 --------QLKEVRKKCAE-------EAQLISSLKAELTSQESQISTYEEELAKAREELS 141
QLK++ ++ A L SS K E + + +EL R++
Sbjct: 351 SDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRE 410
Query: 142 RLQQETAELEESVESGKAQL------EPLQQHLQDSQQEISSMQMKLME-MKDLENHN 192
RLQ+E ++ E +++ K Q+ E + + L D + +L E + DLE N
Sbjct: 411 RLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMN 468
Score = 43.1 bits (100), Expect = 7e-04
Identities = 36/201 (17%), Positives = 91/201 (45%), Gaps = 18/201 (8%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEV------QDLQDEVQRENTNLQKLQAQKQQVQELLDE 86
+++ ++++L + E TI + +V +++ + + N NL++ + ++ L+
Sbjct: 407 QQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEA 466
Query: 87 LDEQKAQLEEQLKEVRKKCAEEAQL----ISSLKAELTSQESQISTYEEELAKAREELSR 142
++E +L+E +E + E+ + + + + + + ++ Y++ + K R+ +
Sbjct: 467 MNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAH 526
Query: 143 LQQETAELEESVE-SGKAQLEP------LQQHLQDSQQEISSMQMKLMEMKDLE-NHNSQ 194
LQ EL E S + Q +P + +++ +++M+L +M+ + N +
Sbjct: 527 LQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMS 586
Query: 195 LNWCSSPHSILVNGATDYCSL 215
L P S L G C L
Sbjct: 587 LLTAFMPDSFLRPGGDHDCVL 607
Score = 34.7 bits (78), Expect = 0.25
Identities = 26/109 (23%), Positives = 53/109 (48%), Gaps = 8/109 (7%)
Query: 42 LKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDE-LDEQKAQLEEQLKE 100
L+++E IK+ ++ +E+ N L L+ + + DE +++ + +LEE
Sbjct: 945 LEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQAL 1004
Query: 101 VRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAE 149
+RKK E + + +L+A+ I E E A+ ++ L+ + T E
Sbjct: 1005 LRKKEKEFEETMDALQAD-------IDQLEAEKAELKQRLNSQSKRTIE 1046
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 64.3 bits (155), Expect = 3e-10
Identities = 62/255 (24%), Positives = 114/255 (44%), Gaps = 32/255 (12%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQ 93
EK ++Q+++E E+ +++ S Q LQ E L+KL+ ++ +++ +L ++K
Sbjct: 937 EKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKL 996
Query: 94 LEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEEL---AKAREELSR-------- 142
LE+++ E EE + SL E+ I+ EE L K R+EL +
Sbjct: 997 LEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGD 1056
Query: 143 ---LQQETAELEESVESGKAQL----EPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQL 195
L + AEL+ + K QL E LQ L ++E + M L ++++LE+ S+L
Sbjct: 1057 STDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISEL 1116
Query: 196 NWCSSPHSILVNGATDYCSLSTSSSETANLNEHVEG-----QSNLESEPIHQESPARSSP 250
+ ++ S + + + +L E +E + L+S QE ++
Sbjct: 1117 Q---------EDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQ 1167
Query: 251 ELLPSGVTDENEVTT 265
E+ T E E T
Sbjct: 1168 EVNILKKTLEEEAKT 1182
Score = 57.8 bits (138), Expect = 3e-08
Identities = 33/163 (20%), Positives = 86/163 (52%), Gaps = 8/163 (4%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
+ K +EQ ++E + +++ E+Q +D R NLQ ++AQ ++ + DE E+K
Sbjct: 1525 KSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKK 1584
Query: 93 --------QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQ 144
++E +L++ RK+ + L+ +L E+ I + + +A ++L +LQ
Sbjct: 1585 KQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQ 1644
Query: 145 QETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
+ + ++ +A E + +++++++ SM+ +++++++
Sbjct: 1645 AQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQE 1687
Score = 53.5 bits (127), Expect = 5e-07
Identities = 45/177 (25%), Positives = 87/177 (49%), Gaps = 19/177 (10%)
Query: 32 SREKNNVEQDLKEKED---TIKQRTSEVQDLQDEVQREN----TNLQKLQAQKQQVQELL 84
+ E++ E + +EKE ++ + E + + E++R N T ++ L + K V + +
Sbjct: 1461 AEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSV 1520
Query: 85 DELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSR-L 143
EL++ K LE+Q++E++ + E L+ EL + E E L + + R L
Sbjct: 1521 HELEKSKRALEQQVEEMKTQLEE-------LEDELQATEDAKLRLEVNLQAMKAQFERDL 1573
Query: 144 QQETAELEESVESGKAQLEPLQQHLQDSQQEIS---SMQMKL-MEMKDLENHNSQLN 196
Q + EE + Q+ ++ L+D +++ S + + KL M++KDLE H N
Sbjct: 1574 QGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSAN 1630
Score = 51.6 bits (122), Expect = 2e-06
Identities = 53/250 (21%), Positives = 112/250 (44%), Gaps = 18/250 (7%)
Query: 49 IKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEE 108
+ ++ E+ ++E+ + + + +++ L +L +K QL+EQL+ + CAE
Sbjct: 840 VSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEA 899
Query: 109 AQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHL 168
+L + L A+ E E + + E LQ E +++++++ + QLE +
Sbjct: 900 EELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESAR 959
Query: 169 QDSQQEISSMQMKLMEMKD----LENHNSQLNWCSSPHSILVNGATDYCSLSTSSSETAN 224
Q Q E + + KL ++++ LE+ N +L + +L + ++ + T E +
Sbjct: 960 QKLQLEKVTTEAKLKKLEEEQIILEDQNCKL---AKEKKLLEDRIAEFTTNLTEEEEKSK 1016
Query: 225 -----LNEHVEGQSNLESEPIHQESPARSSPE----LLPSGVTDENEVTTAVTEKVCSEL 275
N+H ++LE E + +E R E L TD ++ + ++ +EL
Sbjct: 1017 SLAKLKNKHEAMITDLE-ERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQI-AEL 1074
Query: 276 DNNRHSKEED 285
KEE+
Sbjct: 1075 KMQLAKKEEE 1084
Score = 51.2 bits (121), Expect = 3e-06
Identities = 29/154 (18%), Positives = 74/154 (48%), Gaps = 1/154 (0%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQ 93
EK +E + + E+ +++ + + D +++ N + ++ + + + + Q
Sbjct: 1723 EKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQ 1782
Query: 94 LEEQLKEVRKKCAE-EAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
LE Q KE++ K E E + S KA +T+ E++I+ EE+L +E ++ E+
Sbjct: 1783 LERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEK 1842
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
++ Q++ +++ + + + +L ++K
Sbjct: 1843 KLKDVLLQVDDERRNAEQYKDQADKASTRLKQLK 1876
Score = 49.7 bits (117), Expect = 7e-06
Identities = 44/188 (23%), Positives = 86/188 (45%), Gaps = 43/188 (22%)
Query: 38 VEQDLKEKE-------DTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQ----ELLDE 86
+E++L+E++ D +K+ ++ + ++ E ++ QK + +QQ++ EL +
Sbjct: 1734 LEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVK 1793
Query: 87 LDEQK------------------AQLEEQL----KEVRKKCAEEAQLISSLK---AELTS 121
L E + AQLEEQL KE + C + + LK ++
Sbjct: 1794 LQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDD 1853
Query: 122 QESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQ-------E 174
+ Y+++ KA L +L+++ E EE + A LQ+ L+D+ + E
Sbjct: 1854 ERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNRE 1913
Query: 175 ISSMQMKL 182
+SS++ KL
Sbjct: 1914 VSSLKNKL 1921
Score = 49.3 bits (116), Expect = 1e-05
Identities = 53/185 (28%), Positives = 81/185 (43%), Gaps = 37/185 (20%)
Query: 44 EKEDTIKQRTSEV----------QDLQDEVQRENTN-------LQKLQAQKQQVQELLDE 86
E ED KQR+ V +DL+ + N N L+KLQAQ + LD+
Sbjct: 1597 ELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDD 1656
Query: 87 LDEQKAQLEEQLKEVRKKC-AEEAQLISSLKAELTSQE---SQISTYEEELAK------- 135
+ ++ Q KE KK + EA++I L+ EL + E Q +ELA
Sbjct: 1657 TRASREEILAQAKENEKKLKSMEAEMI-QLQEELAAAERAKRQAQQERDELADEIANSSG 1715
Query: 136 ----AREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENH 191
A EE RL+ A+LEE +E + E + L+ + +I + L +LE
Sbjct: 1716 KGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDL----NLERS 1771
Query: 192 NSQLN 196
++Q N
Sbjct: 1772 HAQKN 1776
Score = 48.5 bits (114), Expect = 2e-05
Identities = 33/146 (22%), Positives = 71/146 (48%), Gaps = 17/146 (11%)
Query: 42 LKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEV 101
++EK+ + R +E++ LQ ++ E LQ+ Q Q EL E +E +A+L + +E+
Sbjct: 857 VREKQLAAENRLTEMETLQSQLMAEKLQLQE---QLQAETELCAEAEELRARLTAKKQEL 913
Query: 102 RKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQL 161
+ C + E+++ EE + E ++QQ ELEE +E ++
Sbjct: 914 EEICHD--------------LEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESAR 959
Query: 162 EPLQQHLQDSQQEISSMQMKLMEMKD 187
+ LQ ++ ++ ++ + + ++D
Sbjct: 960 QKLQLEKVTTEAKLKKLEEEQIILED 985
Score = 48.1 bits (113), Expect = 2e-05
Identities = 60/268 (22%), Positives = 107/268 (39%), Gaps = 57/268 (21%)
Query: 38 VEQDLKEKEDTIK---QRTSEVQDLQDEVQRENTNLQKLQAQKQQV--------QELLDE 86
VE++ +K +K + S++ +LQ++++ E + K + QK+ + EL D
Sbjct: 1092 VEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDT 1151
Query: 87 LDEQKAQ-----------------LEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTY 129
LD AQ LEE+ K + E Q S EL Q Q
Sbjct: 1152 LDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRV 1211
Query: 130 EEELAKAREELSRLQQETAELEESVESGK-----------AQLEPLQQHLQDSQQEISSM 178
+ L KA++ L + E A + + GK AQL+ LQ + ++ + +
Sbjct: 1212 KANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTEL 1271
Query: 179 QMKLMEMK-DLENHNSQLNWCSSPHSILVNGATDYCSLSTSSSETANLNE---------- 227
K+ +++ +L+N L+ S S L D+ +L + +T L +
Sbjct: 1272 ADKVTKLQVELDNVTGLLSQSDSKSSKLTK---DFSALESQLQDTQELLQEENRQKLSLS 1328
Query: 228 ----HVEGQSNLESEPIHQESPARSSPE 251
VE + N E + +E A+ + E
Sbjct: 1329 TKLKQVEDEKNSFREQLEEEEEAKHNLE 1356
Score = 48.1 bits (113), Expect = 2e-05
Identities = 30/154 (19%), Positives = 75/154 (48%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
+ K +E + E + +K D + + ++ LQ+LQ + + + + EL ++
Sbjct: 1217 KAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVT 1276
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
+L+ +L V ++ S L + ++ ESQ+ +E L + + L + ++E+
Sbjct: 1277 KLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVED 1336
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
S + QLE ++ + +++I+++ ++ +MK
Sbjct: 1337 EKNSFREQLEEEEEAKHNLEKQIATLHAQVADMK 1370
Score = 48.1 bits (113), Expect = 2e-05
Identities = 34/154 (22%), Positives = 74/154 (48%), Gaps = 5/154 (3%)
Query: 41 DLKEKEDTIKQRTSEVQDLQDEVQRENTNLQ----KLQAQKQQVQELLDELDEQKAQLEE 96
D + K ++ + E+Q +E +R T L KLQ + V LL + D + ++L +
Sbjct: 1242 DSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTK 1301
Query: 97 QLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVES 156
+ + + +L+ + S +++ E+E RE+L ++ LE+ + +
Sbjct: 1302 DFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIAT 1361
Query: 157 GKAQLEPLQQHLQDSQQEI-SSMQMKLMEMKDLE 189
AQ+ +++ ++DS + ++ ++K KDLE
Sbjct: 1362 LHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLE 1395
Score = 47.4 bits (111), Expect = 4e-05
Identities = 41/198 (20%), Positives = 88/198 (44%), Gaps = 39/198 (19%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDL-------QDEVQRENTNLQKLQAQKQQVQELLD 85
+ + +E D + D I + +++ +L ++E+Q +++ AQK + +
Sbjct: 1048 KTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIR 1107
Query: 86 ELDEQKAQLEEQLKEVR-------KKCAEEAQLISSLKAEL------------------- 119
EL+ Q ++L+E L+ R K+ + + + +LK EL
Sbjct: 1108 ELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQ 1167
Query: 120 ------TSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQ 173
+ E + T+E ++ + R++ S+ +E AE E + KA LE +Q L++ +
Sbjct: 1168 EVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERG 1227
Query: 174 EISSMQMKLMEMKDLENH 191
E+++ L++ K H
Sbjct: 1228 ELANEVKVLLQGKGDSEH 1245
Score = 47.0 bits (110), Expect = 5e-05
Identities = 35/149 (23%), Positives = 68/149 (45%), Gaps = 14/149 (9%)
Query: 54 SEVQDLQDEVQREN-------TNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCA 106
S++QD Q+ +Q EN T L++++ +K +E L+E +E K LE+Q+ + + A
Sbjct: 1308 SQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVA 1367
Query: 107 EEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQ 166
+ +K ++ + T EE K +++L L Q E + + + LQQ
Sbjct: 1368 D-------MKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQ 1420
Query: 167 HLQDSQQEISSMQMKLMEMKDLENHNSQL 195
L D ++ + ++ + QL
Sbjct: 1421 ELDDLLVDLDHQRQSACNLEKKQKKFDQL 1449
Score = 46.2 bits (108), Expect = 8e-05
Identities = 43/189 (22%), Positives = 84/189 (44%), Gaps = 27/189 (14%)
Query: 18 VADVLKY--SCIVCWSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQA 75
VAD+ K + C + E+ V++ L++ + + QR E D++++ T LQ
Sbjct: 1366 VADMKKKMEDSVGCLETAEE--VKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQ---- 1419
Query: 76 QKQQVQELLDELDEQK---AQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEE 132
Q++ +LL +LD Q+ LE++ K+ + AEE + + E E++ E +
Sbjct: 1420 --QELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETK 1477
Query: 133 LAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQD--------------SQQEISSM 178
L ++ AELE + + ++E L D +Q++ M
Sbjct: 1478 ALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEM 1537
Query: 179 QMKLMEMKD 187
+ +L E++D
Sbjct: 1538 KTQLEELED 1546
Score = 45.8 bits (107), Expect = 1e-04
Identities = 36/169 (21%), Positives = 79/169 (46%), Gaps = 4/169 (2%)
Query: 29 CWSSREKNNVEQDLKEKEDTIKQRTSEVQDLQD-EVQRENTNLQKLQAQKQQVQELLDEL 87
C +++ +Q L E E TI + +E +D + E + + T L ++ E EL
Sbjct: 1437 CNLEKKQKKFDQLLAE-EKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAEL 1495
Query: 88 DEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQET 147
+ Q +++++ + + + L+ + E Q+ + +L + +EL +
Sbjct: 1496 ERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAK 1555
Query: 148 AELEESVESGKAQLE-PLQQHLQDSQQEISSMQMKLMEMK-DLENHNSQ 194
LE ++++ KAQ E LQ + S+++ + ++ EM+ +LE+ Q
Sbjct: 1556 LRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQ 1604
Score = 45.4 bits (106), Expect = 1e-04
Identities = 34/153 (22%), Positives = 71/153 (46%), Gaps = 4/153 (2%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E+ + ++E+ +K R ++ ++ + T +L A+K Q+QE L E A+ EE
Sbjct: 845 EEMMAKEEELVKVREKQLA-AENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 903
Query: 99 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELE---ESVE 155
+ K E ++ L+A + +E + + E K ++ + L+++ E E + ++
Sbjct: 904 ARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQ 963
Query: 156 SGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDL 188
K E + L++ Q + KL + K L
Sbjct: 964 LEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKL 996
Score = 45.4 bits (106), Expect = 1e-04
Identities = 33/149 (22%), Positives = 68/149 (45%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQ 93
E +NV L + + + T + L+ ++Q LQ+ QK + L +++++K
Sbjct: 1281 ELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNS 1340
Query: 94 LEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEES 153
EQL+E + + I++L A++ + ++ L A E +LQ++ L +
Sbjct: 1341 FREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQR 1400
Query: 154 VESGKAQLEPLQQHLQDSQQEISSMQMKL 182
E A + L++ QQE+ + + L
Sbjct: 1401 HEEKVAAYDKLEKTKTRLQQELDDLLVDL 1429
Score = 43.5 bits (101), Expect = 5e-04
Identities = 34/160 (21%), Positives = 73/160 (45%), Gaps = 6/160 (3%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
EQ ++K+ ++Q +L+DE ++ + + + + +++L +D +E +
Sbjct: 1578 EQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAI 1637
Query: 99 KEVRKKCAEEAQLISSLKAELTSQE---SQISTYEEELAKAREELSRLQQETAELEESVE 155
K++RK A+ + L S+E +Q E++L E+ +LQ+E A E +
Sbjct: 1638 KQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKR 1697
Query: 156 SGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQL 195
+ + + L + +S + L E + LE +QL
Sbjct: 1698 QAQQERDELADEIANSS---GKGALALEEKRRLEARIAQL 1734
Score = 41.2 bits (95), Expect = 0.003
Identities = 53/234 (22%), Positives = 93/234 (39%), Gaps = 80/234 (34%)
Query: 35 KNNVEQ----------DLKEK-EDTI--------------------KQRTSEVQDLQDEV 63
K+N+E+ D+K+K ED++ QR E D++
Sbjct: 1352 KHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKL 1411
Query: 64 QRENTNLQKLQAQKQQVQELLDELDEQK---AQLEEQLKEVRKKCAEEAQLISSL----- 115
++ T LQ Q++ +LL +LD Q+ LE++ K+ + AEE + +
Sbjct: 1412 EKTKTRLQ------QELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERD 1465
Query: 116 --------------------------KAELTSQESQISTYEEELAKAREELSR----LQQ 145
KAEL Q T E+L +++++ + L++
Sbjct: 1466 RAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEK 1525
Query: 146 ETAELEESVESGKAQLEPLQQHLQDSQQ-----EISSMQMKLMEMKDLENHNSQ 194
LE+ VE K QLE L+ LQ ++ E++ MK +DL+ + Q
Sbjct: 1526 SKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQ 1579
Score = 38.5 bits (88), Expect = 0.017
Identities = 37/180 (20%), Positives = 79/180 (43%), Gaps = 25/180 (13%)
Query: 31 SSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD-- 88
+SRE+ + KE E +K +E+ LQ+E L + K+Q Q+ DEL
Sbjct: 1659 ASREE--ILAQAKENEKKLKSMEAEMIQLQEE-------LAAAERAKRQAQQERDELADE 1709
Query: 89 ------------EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKA 136
E+K +LE ++ ++ ++ EE + L QI +L
Sbjct: 1710 IANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLE 1769
Query: 137 REELSRLQQETAELEESVESGKAQLEPLQQHLQDS-QQEISSMQMKLMEMKD-LENHNSQ 194
R + + +LE + K +L+ ++ ++ + I++++ K+ ++++ L+N +
Sbjct: 1770 RSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKE 1829
Score = 38.5 bits (88), Expect = 0.017
Identities = 20/69 (28%), Positives = 40/69 (57%), Gaps = 3/69 (4%)
Query: 34 EKNNVEQ--DLKEKEDT-IKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQ 90
E+ N EQ D +K T +KQ ++++ ++E QR N + +KLQ + + E D ++ +
Sbjct: 1854 ERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNRE 1913
Query: 91 KAQLEEQLK 99
+ L+ +L+
Sbjct: 1914 VSSLKNKLR 1922
Score = 37.7 bits (86), Expect = 0.029
Identities = 31/152 (20%), Positives = 72/152 (47%), Gaps = 16/152 (10%)
Query: 32 SREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLD-ELDEQ 90
+++ N Q L+ + +K + E++ + ++ L+A+ Q++E LD E E+
Sbjct: 1773 AQKNENARQQLERQNKELKVKLQEMEGTVKS--KYKASITALEAKIAQLEEQLDNETKER 1830
Query: 91 KA------QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSR-- 142
+A + E++LK+V + +E + K + +++ + +L +A EE R
Sbjct: 1831 QAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRAN 1890
Query: 143 -----LQQETAELEESVESGKAQLEPLQQHLQ 169
LQ+E + E+ ++ ++ L+ L+
Sbjct: 1891 ASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
Score = 37.0 bits (84), Expect = 0.050
Identities = 26/145 (17%), Positives = 63/145 (43%), Gaps = 4/145 (2%)
Query: 42 LKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEV 101
++E +DT R +++ + + L+ ++A+ Q+QE L + K Q +++ E+
Sbjct: 1651 MRELDDTRASR----EEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDEL 1706
Query: 102 RKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQL 161
+ A + + E E++I+ EEEL + + + + ++ L
Sbjct: 1707 ADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDL 1766
Query: 162 EPLQQHLQDSQQEISSMQMKLMEMK 186
+ H Q ++ ++ + E+K
Sbjct: 1767 NLERSHAQKNENARQQLERQNKELK 1791
Score = 34.7 bits (78), Expect = 0.25
Identities = 33/159 (20%), Positives = 75/159 (47%), Gaps = 17/159 (10%)
Query: 32 SREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQK 91
+R+K ++ LK+ ED ++ S + L++E + ++ +++ QV ++ ++++
Sbjct: 1321 NRQKLSLSTKLKQVED---EKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSV 1377
Query: 92 AQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELE 151
L E +EV++K ++ + +S E +++ Y+ K + +RLQQE +L
Sbjct: 1378 GCL-ETAEEVKRKLQKDLEGLSQ------RHEEKVAAYD----KLEKTKTRLQQELDDLL 1426
Query: 152 ESVE---SGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
++ LE Q+ E ++ K E +D
Sbjct: 1427 VDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERD 1465
Score = 32.0 bits (71), Expect = 1.6
Identities = 26/123 (21%), Positives = 51/123 (41%), Gaps = 18/123 (14%)
Query: 35 KNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQL 94
+ ++ + KE++ KQ + L+D + + + + + K Q + L + K QL
Sbjct: 1820 EEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQL 1879
Query: 95 EEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESV 154
EE EEAQ ++ + +L + EL A E + +E + L+ +
Sbjct: 1880 EE--------AEEEAQRANASRRKL----------QRELEDATETADAMNREVSSLKNKL 1921
Query: 155 ESG 157
G
Sbjct: 1922 RRG 1924
Score = 30.0 bits (66), Expect = 6.1
Identities = 38/170 (22%), Positives = 70/170 (41%), Gaps = 17/170 (10%)
Query: 118 ELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQ---E 174
+++ QE ++ EEEL K RE+ + E+E A+ LQ+ LQ + E
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAE 898
Query: 175 ISSMQMKLMEMKDLENHNSQLNWCSSPHSILVNGATDYCSLSTSSSETANLNEHVEGQSN 234
++ +L K +L V + C +E + ++++
Sbjct: 899 AEELRARLTAKK------QELEEICHDLEARVEEEEERC--QHLQAEKKKMQQNIQ---E 947
Query: 235 LESEPIHQESPARSSPELLPSGVTDENEVTTAVTEKVCSELDNNRHSKEE 284
LE E + +E AR +L VT E ++ E++ E N + +KE+
Sbjct: 948 LE-EQLEEEESARQKLQL--EKVTTEAKLKKLEEEQIILEDQNCKLAKEK 994
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 64.3 bits (155), Expect = 3e-10
Identities = 31/149 (20%), Positives = 83/149 (55%), Gaps = 2/149 (1%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E ++E+E ++++ +V++ + +V+ + +++ + Q + + + E +EQ + EEQ+
Sbjct: 156 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQM 215
Query: 99 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 158
++ ++ E+ + + + ++ QE Q+ EE++ K E++ + +++ E EE + +
Sbjct: 216 QKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQE 275
Query: 159 AQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
Q+ L+Q Q Q+E + Q + M ++
Sbjct: 276 EQM--LKQKEQTEQEEQTGEQEEQMREQE 302
Score = 63.5 bits (153), Expect = 5e-10
Identities = 35/149 (23%), Positives = 82/149 (55%), Gaps = 2/149 (1%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
EQ LK+KE T ++ + Q+ Q Q E Q+ Q ++Q+ Q + E +EQ + EEQ+
Sbjct: 276 EQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQ--MREQEEQMGKQEEQM 333
Query: 99 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 158
E +++ E+ + + + ++ QE Q+ EE++ K E++ + +++ + EE + +
Sbjct: 334 WEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQE 393
Query: 159 AQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
Q+ ++ + + ++++ + ++ E K+
Sbjct: 394 EQMGEQKEQMGEQKEQMREQEEQMGEQKE 422
Score = 63.2 bits (152), Expect = 7e-10
Identities = 27/149 (18%), Positives = 85/149 (57%), Gaps = 1/149 (0%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E+ + E+E+ ++++ ++ + +++VQ++ +QK + Q ++ +E + E +EQ + EEQ+
Sbjct: 219 EEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQM 278
Query: 99 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 158
+ +++ +E Q + ++ QE Q+ EE++ + E++ +++ + EE + K
Sbjct: 279 LKQKEQTEQEEQ-TGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQK 337
Query: 159 AQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
Q+ ++ + ++++ + ++ + ++
Sbjct: 338 EQMWEQKEQMWKQEEQMGEQEEQMQKQEE 366
Score = 62.8 bits (151), Expect = 9e-10
Identities = 30/166 (18%), Positives = 89/166 (53%), Gaps = 13/166 (7%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E ++E+E ++++ +V++ + +V+ + +++ Q+ QV+E ++ EQ+ Q+ EQ
Sbjct: 128 EGQVREQEGQVREQEGQVREQEGQVREQEGQVRE---QEGQVREQEGQVREQEGQVREQE 184
Query: 99 KEVRK----------KCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148
+VR+ + E+ + + + ++ QE Q+ EE++ K E++ +++
Sbjct: 185 GQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQ 244
Query: 149 ELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQ 194
+ EE V+ + Q+ ++ +++ ++++ + ++++ K+ Q
Sbjct: 245 KQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQ 290
Score = 62.8 bits (151), Expect = 9e-10
Identities = 33/147 (22%), Positives = 77/147 (52%), Gaps = 1/147 (0%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E ++E+E ++++ +V++ + +V+ + + + + Q + +E + E +EQ + EEQ+
Sbjct: 163 EGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQM 222
Query: 99 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 158
E ++ ++ + + + ++ QE Q+ EE++ K E++ +++ E EE + K
Sbjct: 223 GEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK 282
Query: 159 AQLEPLQQ-HLQDSQQEISSMQMKLME 184
Q E +Q Q+ Q QM+ E
Sbjct: 283 EQTEQEEQTGEQEEQMREQEEQMREQE 309
Score = 62.8 bits (151), Expect = 9e-10
Identities = 27/159 (16%), Positives = 84/159 (52%), Gaps = 1/159 (0%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E ++E+E ++++ ++ + + ++ + + + + Q Q+ +E + E +EQ + EEQ+
Sbjct: 177 EGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQM 236
Query: 99 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 158
E ++ ++ + + + ++ QE Q+ EE++ + E++ + Q+E E EE +
Sbjct: 237 GEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLK-QKEQTEQEEQTGEQE 295
Query: 159 AQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 197
Q+ ++ +++ ++++ + ++ E ++ + W
Sbjct: 296 EQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMW 334
Score = 62.8 bits (151), Expect = 9e-10
Identities = 28/155 (18%), Positives = 86/155 (55%), Gaps = 6/155 (3%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQ------KA 92
E+ ++++E+ + ++ +VQ +++VQ++ ++K + Q ++ +E + E +EQ +
Sbjct: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT 285
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
+ EEQ E ++ E+ + + + ++ QE Q+ EE++ K E++ +++ E +E
Sbjct: 286 EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKE 345
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
+ + Q+ ++ +Q ++++ + ++ + ++
Sbjct: 346 QMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEE 380
Score = 62.4 bits (150), Expect = 1e-09
Identities = 25/155 (16%), Positives = 86/155 (55%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
+E+ E+ E+E+ ++++ ++++ +++++ + +++ + Q + +E + E EQ
Sbjct: 282 KEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMW 341
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
+ +EQ+ + ++ E+ + + + ++ QE Q+ EE++ K E++ + +++ E +E
Sbjct: 342 EQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKE 401
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
+ K Q+ ++ + + ++++ + + E K+
Sbjct: 402 QMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 61.6 bits (148), Expect = 2e-09
Identities = 24/149 (16%), Positives = 86/149 (57%), Gaps = 1/149 (0%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E+ ++E+E+ ++++ ++ +++ ++E ++ + ++Q +E + E +EQ + EEQ+
Sbjct: 261 EEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQ-EEQMREQEEQMREQEEQM 319
Query: 99 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 158
+E ++ ++ + + K ++ Q+ Q+ EE++ + E++ + +++ + EE + +
Sbjct: 320 REQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQE 379
Query: 159 AQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
Q+ ++ ++ ++++ + ++ E K+
Sbjct: 380 EQMRKQEEQMRKQEEQMGEQKEQMGEQKE 408
Score = 61.2 bits (147), Expect = 2e-09
Identities = 32/149 (21%), Positives = 80/149 (53%), Gaps = 2/149 (1%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
EQ +++E +KQ+ Q+ Q Q E Q+ Q ++Q+ Q + E +EQ + EEQ+
Sbjct: 269 EQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQ--MREQEEQMREQEEQM 326
Query: 99 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 158
+ ++ E+ + + K ++ QE Q+ EE++ K E++ + +++ + EE + +
Sbjct: 327 GKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQE 386
Query: 159 AQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
Q+ ++ + + ++++ + ++ E ++
Sbjct: 387 EQMRKQEEQMGEQKEQMGEQKEQMREQEE 415
Score = 60.8 bits (146), Expect = 3e-09
Identities = 23/149 (15%), Positives = 89/149 (59%), Gaps = 1/149 (0%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E+ ++++E+ ++++ ++++ +++++ + + K + Q +Q +E E +EQ + EEQ+
Sbjct: 247 EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQ-EEQTGEQEEQMREQEEQM 305
Query: 99 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 158
+E ++ E+ + + + ++ QE Q+ +E++ + +E++ + +++ E EE ++ +
Sbjct: 306 REQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQE 365
Query: 159 AQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
Q+ ++ ++ ++++ + ++ + ++
Sbjct: 366 EQVRKQEEQMRKQEEQMRKQEEQMRKQEE 394
Score = 60.1 bits (144), Expect = 6e-09
Identities = 28/152 (18%), Positives = 85/152 (55%), Gaps = 6/152 (3%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E ++E+E ++++ +V++ + +V+ + +++ Q+ QV+E ++ EQ+ Q+ EQ
Sbjct: 114 EGQVREQEGQVREQEGQVREQEGQVREQEGQVRE---QEGQVREQEGQVREQEGQVREQE 170
Query: 99 KEVRK---KCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVE 155
+VR+ + E+ + + ++ QE Q+ EE++ + E++ + +++ E EE +
Sbjct: 171 GQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMR 230
Query: 156 SGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
+ Q+ ++ +Q ++++ + ++ + ++
Sbjct: 231 KQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEE 262
Score = 60.1 bits (144), Expect = 6e-09
Identities = 26/149 (17%), Positives = 85/149 (57%), Gaps = 1/149 (0%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E+ + E+E+ ++++ ++ + +++++++ + + + Q Q+ +E + + +EQ + EEQ+
Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264
Query: 99 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 158
+E ++ E+ + + K E T QE Q EE++ + E++ +++ E EE + +
Sbjct: 265 REQEEQMREQEEQMLKQK-EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQE 323
Query: 159 AQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
Q+ ++ + + ++++ + ++ + ++
Sbjct: 324 EQMGKQEEQMWEQKEQMWEQKEQMWKQEE 352
Score = 60.1 bits (144), Expect = 6e-09
Identities = 24/155 (15%), Positives = 89/155 (57%), Gaps = 6/155 (3%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELL------DELDEQKA 92
E+ + E+E+ ++++ +VQ +++++++ +++ + Q ++ +E + E +EQ
Sbjct: 233 EEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTG 292
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
+ EEQ++E ++ E+ + + + ++ QE Q+ EE++ + +E++ +++ + EE
Sbjct: 293 EQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEE 352
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
+ + Q++ ++ ++ ++++ + ++ + ++
Sbjct: 353 QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE 387
Score = 60.1 bits (144), Expect = 6e-09
Identities = 23/149 (15%), Positives = 86/149 (57%), Gaps = 1/149 (0%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E+ ++++E+ ++++ ++++ ++++ ++ ++ + Q + +E + E +EQ + EEQ+
Sbjct: 254 EEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQ-EEQTGEQEEQMREQEEQMREQEEQM 312
Query: 99 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 158
+E ++ E+ + + + ++ Q+ Q+ +E++ K E++ +++ + EE V +
Sbjct: 313 REQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQE 372
Query: 159 AQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
Q+ ++ ++ ++++ + ++ E K+
Sbjct: 373 EQMRKQEEQMRKQEEQMRKQEEQMGEQKE 401
Score = 47.0 bits (110), Expect = 5e-05
Identities = 25/152 (16%), Positives = 80/152 (52%), Gaps = 6/152 (3%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E ++E+E ++++ +V++ + +V+ + +++ Q+ QV+E ++ EQ+ Q+ EQ
Sbjct: 79 EGQVREQEGQVREQEGQVREQEGQVREQEGQVRE---QEGQVREQEGQVREQEGQVREQE 135
Query: 99 KEVRK---KCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVE 155
+VR+ + E+ + + ++ QE Q+ E ++ + ++ + + E E +
Sbjct: 136 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMG 195
Query: 156 SGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
+ Q+ ++ + + ++++ + ++ E ++
Sbjct: 196 EQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEE 227
Score = 42.0 bits (97), Expect = 0.002
Identities = 30/162 (18%), Positives = 82/162 (50%), Gaps = 12/162 (7%)
Query: 34 EKNNVE---QDLKEKEDTIK---QRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDEL 87
EK+ ++ ++LK K +T K + +V++ + +V+ + +++ Q+ QV+E ++
Sbjct: 26 EKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVRE---QEGQVREQEGQV 82
Query: 88 DEQKAQLEEQLKEVRK---KCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQ 144
EQ+ Q+ EQ +VR+ + E+ + + ++ QE Q+ E ++ + ++ +
Sbjct: 83 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 142
Query: 145 QETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
+ E E V + Q+ + +++ + ++ + ++ E +
Sbjct: 143 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 184
Score = 40.0 bits (92), Expect = 0.006
Identities = 22/103 (21%), Positives = 60/103 (58%), Gaps = 8/103 (7%)
Query: 30 WSSREKN-NVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD 88
W +E+ E+ + E+E+ ++++ +V+ +++++++ ++K Q ++ + QE +++
Sbjct: 341 WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRK-QEEQMRKQE--EQMG 397
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEE 131
EQK Q+ EQ +++R E+ + + K ++ QE + +E
Sbjct: 398 EQKEQMGEQKEQMR----EQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 37.4 bits (85), Expect = 0.038
Identities = 18/116 (15%), Positives = 61/116 (52%), Gaps = 1/116 (0%)
Query: 71 QKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYE 130
++L+ + ++QE L ++ +K++++ +KE+++K E ++ + ++ QE Q+ E
Sbjct: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRK-LETDKIPLPQEGQVREQEGQVREQE 65
Query: 131 EELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
++ + ++ + + E E V + Q+ + +++ + ++ + ++ E +
Sbjct: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 121
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 63.9 bits (154), Expect = 4e-10
Identities = 29/169 (17%), Positives = 91/169 (53%), Gaps = 11/169 (6%)
Query: 30 WSSREK-NNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD 88
W EK + E+ ++E+ED + ++ ++++ +++++ + + + + + ++ E + E +
Sbjct: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148
E+ + EE+++E +K E+ + QE ++ +E++ + EE+ R +++
Sbjct: 388 EEMWRQEEKIREQEEKRQEK----------MWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
Query: 149 ELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 197
ELEE ++ + +L +++ +Q+ ++++ + K+ ++ + W
Sbjct: 438 ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486
Score = 53.9 bits (128), Expect = 4e-07
Identities = 29/169 (17%), Positives = 91/169 (53%), Gaps = 11/169 (6%)
Query: 30 WSSREKNNVEQDLKEK-----EDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELL 84
W EK +++ +++ E ++++ ++++ ++E+ R+ +++L+ Q +E L
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 85 DELDE------QKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE 138
E++E +K Q +E+ + +++ +E + + + +L QE +I EE++ + E
Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510
Query: 139 ELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
++ +++ E EE ++ + ++ + L ++++ +++L E+++
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559
Score = 52.8 bits (125), Expect = 9e-07
Identities = 30/157 (19%), Positives = 87/157 (55%), Gaps = 8/157 (5%)
Query: 33 REKNNVEQD--LKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDE- 89
+EK EQD ++E+E+ + ++ ++++L++ +Q + L++++ + Q+ +E + E +E
Sbjct: 411 QEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEK 470
Query: 90 -----QKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQ 144
+K Q +E+ ++K ++ + I + ++ QE ++ EE++ + E++ R +
Sbjct: 471 IQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQE 530
Query: 145 QETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMK 181
++ E E + + +++ + LQ+ ++ + + K
Sbjct: 531 EKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQK 567
Score = 52.0 bits (123), Expect = 2e-06
Identities = 52/264 (19%), Positives = 116/264 (43%), Gaps = 39/264 (14%)
Query: 34 EKNNVEQDLKEKEDTIK--QRTSEVQDLQDEVQRENTNLQKLQAQKQ-QVQE-----LLD 85
EK+ ++ ++K+ + ++ Q Q LQ E R LQ + A+ Q QV+E LL+
Sbjct: 233 EKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLN 292
Query: 86 ELDEQKA-QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQ 144
+ E+K + EE+++E +K E+ I + ++ QE ++ EE++ + +++ R +
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
Query: 145 QETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLM----EMKDLENHNSQLNWCSS 200
++ E EE + + ++ ++ +++ ++I + ++ ++++ E + W
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW--- 409
Query: 201 PHSILVNGATDYCSLSTSSSETANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDE 260
+ + E E E E QE R E++ D+
Sbjct: 410 -------------------RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM----QDQ 446
Query: 261 NEVTTAVTEKVCSELDNNRHSKEE 284
E V EK+ E + + +E+
Sbjct: 447 EEKLREVEEKMQEEEEKMQEQEEK 470
Score = 50.4 bits (119), Expect = 4e-06
Identities = 35/159 (22%), Positives = 80/159 (50%), Gaps = 16/159 (10%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLD------ELDEQKA 92
E+ L+E E+ +++ ++Q+ ++++QR+ +Q+ + + + ++LL E +E+
Sbjct: 447 EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMW 506
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
+ EE++ E +K E+ + + + ++ QE ++ EE++ + L L++ +L +
Sbjct: 507 RQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQ 566
Query: 153 SV--------ESGKAQLEPLQQHLQD--SQQEISSMQMK 181
ESG +L L LQ QE S+Q +
Sbjct: 567 KAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQ 605
Score = 47.4 bits (111), Expect = 4e-05
Identities = 32/155 (20%), Positives = 85/155 (54%), Gaps = 16/155 (10%)
Query: 39 EQDLKEKEDTIKQRTSEVQDL---QDEVQRENTNLQKLQAQKQQV---QELLDELDEQKA 92
E+++ +E+ I+++ + Q+ Q++ RE +K++ Q++++ +E + EL+E
Sbjct: 387 EEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD--EKIREQEEEMWRQEEKIRELEEMMQ 444
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
EE+L+EV +K EE + ++ QE +I EE++ + +EE + Q++ + EE
Sbjct: 445 DQEEKLREVEEKMQEEEE-------KMQEQEEKIQRQEEKI-QEQEEKTWRQEKLLKQEE 496
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
+ + ++ ++ + + ++++ + K+ ++
Sbjct: 497 KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEE 531
Score = 37.0 bits (84), Expect = 0.050
Identities = 32/145 (22%), Positives = 72/145 (49%), Gaps = 20/145 (13%)
Query: 61 DEVQRENTNLQKLQAQKQQVQELL-------DELDEQKAQLEEQLKEVRKKCAEEAQLIS 113
D R T ++KL ++ L +EL E+ A+L+E+L+ V + +E +
Sbjct: 183 DHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVK 242
Query: 114 SLKAELTSQESQISTYEEELAKAREELSR-LQQETAELEESVES-------GKAQLEPL- 164
LK +L + +Q+ +++L + L + LQ +A+L+ VE + Q E +
Sbjct: 243 DLKRKL--ERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300
Query: 165 --QQHLQDSQQEISSMQMKLMEMKD 187
++ +Q+ ++++ ++K+ E ++
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEE 325
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 63.9 bits (154), Expect = 4e-10
Identities = 29/169 (17%), Positives = 91/169 (53%), Gaps = 11/169 (6%)
Query: 30 WSSREK-NNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD 88
W EK + E+ ++E+ED + ++ ++++ +++++ + + + + + ++ E + E +
Sbjct: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148
E+ + EE+++E +K E+ + QE ++ +E++ + EE+ R +++
Sbjct: 388 EEMWRQEEKIREQEEKRQEK----------MWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
Query: 149 ELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 197
ELEE ++ + +L +++ +Q+ ++++ + K+ ++ + W
Sbjct: 438 ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486
Score = 53.9 bits (128), Expect = 4e-07
Identities = 29/169 (17%), Positives = 91/169 (53%), Gaps = 11/169 (6%)
Query: 30 WSSREKNNVEQDLKEK-----EDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELL 84
W EK +++ +++ E ++++ ++++ ++E+ R+ +++L+ Q +E L
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 85 DELDE------QKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE 138
E++E +K Q +E+ + +++ +E + + + +L QE +I EE++ + E
Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510
Query: 139 ELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
++ +++ E EE ++ + ++ + L ++++ +++L E+++
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559
Score = 52.8 bits (125), Expect = 9e-07
Identities = 30/157 (19%), Positives = 87/157 (55%), Gaps = 8/157 (5%)
Query: 33 REKNNVEQD--LKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDE- 89
+EK EQD ++E+E+ + ++ ++++L++ +Q + L++++ + Q+ +E + E +E
Sbjct: 411 QEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEK 470
Query: 90 -----QKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQ 144
+K Q +E+ ++K ++ + I + ++ QE ++ EE++ + E++ R +
Sbjct: 471 IQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQE 530
Query: 145 QETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMK 181
++ E E + + +++ + LQ+ ++ + + K
Sbjct: 531 EKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQK 567
Score = 52.0 bits (123), Expect = 2e-06
Identities = 52/264 (19%), Positives = 116/264 (43%), Gaps = 39/264 (14%)
Query: 34 EKNNVEQDLKEKEDTIK--QRTSEVQDLQDEVQRENTNLQKLQAQKQ-QVQE-----LLD 85
EK+ ++ ++K+ + ++ Q Q LQ E R LQ + A+ Q QV+E LL+
Sbjct: 233 EKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLN 292
Query: 86 ELDEQKA-QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQ 144
+ E+K + EE+++E +K E+ I + ++ QE ++ EE++ + +++ R +
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
Query: 145 QETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLM----EMKDLENHNSQLNWCSS 200
++ E EE + + ++ ++ +++ ++I + ++ ++++ E + W
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW--- 409
Query: 201 PHSILVNGATDYCSLSTSSSETANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDE 260
+ + E E E E QE R E++ D+
Sbjct: 410 -------------------RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM----QDQ 446
Query: 261 NEVTTAVTEKVCSELDNNRHSKEE 284
E V EK+ E + + +E+
Sbjct: 447 EEKLREVEEKMQEEEEKMQEQEEK 470
Score = 50.4 bits (119), Expect = 4e-06
Identities = 35/159 (22%), Positives = 80/159 (50%), Gaps = 16/159 (10%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLD------ELDEQKA 92
E+ L+E E+ +++ ++Q+ ++++QR+ +Q+ + + + ++LL E +E+
Sbjct: 447 EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMW 506
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
+ EE++ E +K E+ + + + ++ QE ++ EE++ + L L++ +L +
Sbjct: 507 RQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQ 566
Query: 153 SV--------ESGKAQLEPLQQHLQD--SQQEISSMQMK 181
ESG +L L LQ QE S+Q +
Sbjct: 567 KAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQ 605
Score = 47.4 bits (111), Expect = 4e-05
Identities = 32/155 (20%), Positives = 85/155 (54%), Gaps = 16/155 (10%)
Query: 39 EQDLKEKEDTIKQRTSEVQDL---QDEVQRENTNLQKLQAQKQQV---QELLDELDEQKA 92
E+++ +E+ I+++ + Q+ Q++ RE +K++ Q++++ +E + EL+E
Sbjct: 387 EEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD--EKIREQEEEMWRQEEKIRELEEMMQ 444
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
EE+L+EV +K EE + ++ QE +I EE++ + +EE + Q++ + EE
Sbjct: 445 DQEEKLREVEEKMQEEEE-------KMQEQEEKIQRQEEKI-QEQEEKTWRQEKLLKQEE 496
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
+ + ++ ++ + + ++++ + K+ ++
Sbjct: 497 KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEE 531
Score = 38.1 bits (87), Expect = 0.022
Identities = 32/145 (22%), Positives = 73/145 (50%), Gaps = 20/145 (13%)
Query: 61 DEVQRENTNLQKLQAQKQQVQELL-------DELDEQKAQLEEQLKEVRKKCAEEAQLIS 113
D R T ++KL ++ + L +EL E+ A+L+E+L+ V + +E +
Sbjct: 183 DHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVK 242
Query: 114 SLKAELTSQESQISTYEEELAKAREELSR-LQQETAELEESVES-------GKAQLEPL- 164
LK +L + +Q+ +++L + L + LQ +A+L+ VE + Q E +
Sbjct: 243 DLKRKL--ERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300
Query: 165 --QQHLQDSQQEISSMQMKLMEMKD 187
++ +Q+ ++++ ++K+ E ++
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEE 325
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 63.9 bits (154), Expect = 4e-10
Identities = 42/165 (25%), Positives = 90/165 (54%), Gaps = 8/165 (4%)
Query: 38 VEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQ 97
+E L+E E +E++ ++E R+ +++L+ +Q++QE L +L+ + + EE
Sbjct: 396 LEGQLREAEQARASMQAEMELKEEEAARQRQRIKELEEMQQRLQEAL-QLEVKARRDEES 454
Query: 98 LKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESG 157
++ + + EE + LK + +E Q E + +A++E LQQE A+ S++
Sbjct: 455 VRIAQTRLLEEEE--EKLKQLMQLKEEQ----ERYIERAQQEKEELQQEMAQQSRSLQQA 508
Query: 158 KAQLEPLQQHLQDSQQEISSMQMKLMEMK-DLENHNSQLNWCSSP 201
+ QLE ++Q+ Q + +++ + Q KL + ++++ N Q+N P
Sbjct: 509 QQQLEEVRQNRQRADEDVEAAQRKLRQASTNVKHWNVQMNRLMHP 553
Score = 55.5 bits (132), Expect = 1e-07
Identities = 41/165 (24%), Positives = 84/165 (50%), Gaps = 13/165 (7%)
Query: 35 KNNVEQDLKEK-----EDTIKQRTSE------VQDLQDEVQRENTNLQKLQAQKQQVQEL 83
K ++ +DLK+K E ++R ++ +Q LQ+E +R+ L+ LQ ++Q + L
Sbjct: 318 KTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQRQAERL 377
Query: 84 LDELDEQKAQLEEQLKEVRKKCAEEA-QLISSLKAELTSQESQISTYEEELAKAREELSR 142
L E +E++ +L++ + EA Q +S++AE+ +E + + + + K EE+ +
Sbjct: 378 LQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMELKEEEAARQRQRI-KELEEMQQ 436
Query: 143 LQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
QE +LE + + Q L + ++E M+L E ++
Sbjct: 437 RLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKEEQE 481
Score = 48.9 bits (115), Expect = 1e-05
Identities = 44/175 (25%), Positives = 89/175 (50%), Gaps = 16/175 (9%)
Query: 35 KNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQL 94
+ E+ L+E+E+ +R S+ ++LQ ++ + ++ +A Q EL +E ++ Q
Sbjct: 371 QRQAERLLQEEEE---RRRSQHRELQQALEGQLREAEQARASMQAEMELKEEEAARQRQR 427
Query: 95 EEQLKEVRKKCAEEAQL-ISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEES 153
++L+E++++ E QL + + + E + + +Q EEE E+L +L Q E E
Sbjct: 428 IKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEE----EEKLKQLMQLKEEQERY 483
Query: 154 VESGKAQLEPLQQH-------LQDSQQEISSM-QMKLMEMKDLENHNSQLNWCSS 200
+E + + E LQQ LQ +QQ++ + Q + +D+E +L S+
Sbjct: 484 IERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQAST 538
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
sapiens]
Length = 1478
Score = 63.5 bits (153), Expect = 5e-10
Identities = 47/174 (27%), Positives = 95/174 (54%), Gaps = 11/174 (6%)
Query: 32 SREKNNVEQDLKEKEDTI-KQRTSEVQDLQDEVQ---RENTNLQKLQAQKQ-QVQELLDE 86
+++K + D K +++ I E+Q+L +++Q RE T ++++ Q+ Q+++L+ E
Sbjct: 375 AQQKADTASDTKGRQEPIPSDAAQEMQELGEKLQALERERTKVEEVNRQQSAQLEQLVKE 434
Query: 87 L---DEQKAQLEEQLKEV---RKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREEL 140
L ++ +A LE +KE+ +++ + + Q L L + S++EEELA+ R E
Sbjct: 435 LQLKEDARASLERLVKEMAPLQEELSGKGQEADQLWRRLQELLAHTSSWEEELAELRREK 494
Query: 141 SRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQ 194
+ Q+E LE+ V S QL+ L+ L Q +S ++ + ++ ++H SQ
Sbjct: 495 KQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQKKQLIQDKDHLSQ 548
Score = 55.1 bits (131), Expect = 2e-07
Identities = 48/175 (27%), Positives = 76/175 (43%), Gaps = 30/175 (17%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDL--------------QDEVQRENTNLQKLQAQKQ 78
RE + Q LKE+ + + + + VQ+L DE Q+ L+ LQ +
Sbjct: 821 REHKTLVQQLKEQNEALNR--AHVQELLQCSEREGALQEERADEAQQREEELRALQEELS 878
Query: 79 QVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE 138
Q + +E + A+L+EQL AE + +L E E ++ +EL A+E
Sbjct: 879 QAKCSSEEAQLEHAELQEQLHRANTDTAELGIQVCALTVEKERVEEALACAVQELQDAKE 938
Query: 139 ELSR-----------LQQETAELEESVESGKA---QLEPLQQHLQDSQQEISSMQ 179
SR LQQE L+E +++ KA L LQ L ++Q S+Q
Sbjct: 939 AASREREGLERQVAGLQQEKESLQEKLKAAKAAAGSLPGLQAQLAQAEQRAQSLQ 993
Score = 48.9 bits (115), Expect = 1e-05
Identities = 46/188 (24%), Positives = 78/188 (41%), Gaps = 23/188 (12%)
Query: 17 AVADVLKYSCIVCWSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQ 76
A D + VC + EK VE+ L E+QD ++ RE L++ A
Sbjct: 901 ANTDTAELGIQVCALTVEKERVEEALA-------CAVQELQDAKEAASREREGLERQVAG 953
Query: 77 KQQVQELLDE--------------LDEQKAQLEEQLKEVRKKCAEEAQLIS-SLKAELTS 121
QQ +E L E L Q AQ E++ + +++ +E + L AE+
Sbjct: 954 LQQEKESLQEKLKAAKAAAGSLPGLQAQLAQAEQRAQSLQEAAHQELNTLKFQLSAEIMD 1013
Query: 122 QESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMK 181
+S++ EE R +L ++ EE+VE KA + + L + ++ Q
Sbjct: 1014 YQSRLKNAGEECKSLRGQLEEQGRQLQAAEEAVEKLKATQADMGEKLSCTSNHLAECQAA 1073
Query: 182 LMEMKDLE 189
++ KD E
Sbjct: 1074 MLR-KDKE 1080
Score = 43.1 bits (100), Expect = 7e-04
Identities = 44/209 (21%), Positives = 86/209 (41%), Gaps = 33/209 (15%)
Query: 59 LQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAE 118
++ ++ + LQ + + QQ++E +++ + +L+ + +C ++ QLI L AE
Sbjct: 691 MKAQMAEKEAILQSKEGECQQLREEVEQCQQLAEARHRELRALESQCQQQTQLIEVLTAE 750
Query: 119 LTSQ-------------ESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQ 165
Q +Q++ + +L + E+ RLQ + +L+ + + + +Q
Sbjct: 751 KGQQGVGPPTDNEARELAAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQ 810
Query: 166 QHLQDSQ---QEISSMQMKLMEMKDLEN--HNSQLNWCSSPHSILVNGATDYC------- 213
L ++ +E ++ +L E + N H +L CS L D
Sbjct: 811 SQLSMAEAVLREHKTLVQQLKEQNEALNRAHVQELLQCSEREGALQEERADEAQQREEEL 870
Query: 214 -------SLSTSSSETANLNEHVEGQSNL 235
S + SSE A L EH E Q L
Sbjct: 871 RALQEELSQAKCSSEEAQL-EHAELQEQL 898
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/144 (23%), Positives = 73/144 (50%), Gaps = 10/144 (6%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQD------EVQRENTNLQK-LQAQKQQVQEL-- 83
RE+ VE+ +++ ++Q E+Q +D + +E LQ+ L + Q+ +L
Sbjct: 412 RERTKVEEVNRQQSAQLEQLVKELQLKEDARASLERLVKEMAPLQEELSGKGQEADQLWR 471
Query: 84 -LDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSR 142
L EL + EE+L E+R++ ++ + L+ E+ S Q+ E +LA+ + +S
Sbjct: 472 RLQELLAHTSSWEEELAELRREKKQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSD 531
Query: 143 LQQETAELEESVESGKAQLEPLQQ 166
L+++ +L + + Q+ L++
Sbjct: 532 LEEQKKQLIQDKDHLSQQVGMLER 555
Score = 41.6 bits (96), Expect = 0.002
Identities = 38/149 (25%), Positives = 69/149 (46%), Gaps = 21/149 (14%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA- 92
++ + Q +E E ++ Q L+ ++Q + Q LQ ++ +Q L L+ ++A
Sbjct: 610 QEEELRQANRELEKELQNVVGRNQLLEGKLQALQADYQALQQRESAIQGSLASLEAEQAS 669
Query: 93 ------QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQE 146
Q+E L VRK A+EA +KA++ +E+ + + E E + REE+ + QQ
Sbjct: 670 IRHLGDQMEASLLAVRK--AKEA-----MKAQMAEKEAILQSKEGECQQLREEVEQCQQ- 721
Query: 147 TAELEESVESGKAQLEPLQQHLQDSQQEI 175
E+ +L L+ Q Q I
Sbjct: 722 ------LAEARHRELRALESQCQQQTQLI 744
Score = 41.2 bits (95), Expect = 0.003
Identities = 29/124 (23%), Positives = 62/124 (50%), Gaps = 8/124 (6%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
+ L+ + +++ ++V DLQ +++ + K+Q+Q + +L E QL+EQ
Sbjct: 775 QAQLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQSQLSMAEAVLREHKTLVQQLKEQN 834
Query: 99 KEVRK-------KCAEEAQLISSLKA-ELTSQESQISTYEEELAKAREELSRLQQETAEL 150
+ + + +C+E + +A E +E ++ +EEL++A+ Q E AEL
Sbjct: 835 EALNRAHVQELLQCSEREGALQEERADEAQQREEELRALQEELSQAKCSSEEAQLEHAEL 894
Query: 151 EESV 154
+E +
Sbjct: 895 QEQL 898
Score = 39.7 bits (91), Expect = 0.008
Identities = 36/157 (22%), Positives = 72/157 (45%), Gaps = 17/157 (10%)
Query: 40 QDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLE---- 95
Q++ D +E + DE++ E L +L+ +++Q++E + +LD + +L
Sbjct: 212 QEMVSNFDLNSPLNNEALEGFDEMRLE---LDQLEVREKQLRERMQQLDRENQELRAAVS 268
Query: 96 ---EQLKEVRKK---CAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAE 149
EQL+ R++ AE+ ++ L AEL Q + + + + L L+ AE
Sbjct: 269 QQGEQLQTERERGRTAAEDNVRLTCLVAELQKQWEVTQATQNTVKELQTCLQGLELGAAE 328
Query: 150 LEESVESG----KAQLEPLQQHLQDSQQEISSMQMKL 182
EE + ++ L+PL Q L+ ++ + L
Sbjct: 329 KEEDYHTALRRLESMLQPLAQELEATRDSLDKKNQHL 365
Score = 36.2 bits (82), Expect = 0.085
Identities = 33/166 (19%), Positives = 75/166 (45%), Gaps = 14/166 (8%)
Query: 31 SSREKNNVEQDLKEKEDTIK-QRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDE 89
+ + ++++ ++ +T+K Q ++E+ D Q ++ + L+ Q L+E
Sbjct: 985 AEQRAQSLQEAAHQELNTLKFQLSAEIMDYQSRLKNAGEECKSLRGQ-------LEEQGR 1037
Query: 90 QKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAE 149
Q EE +++++ A+ + +S L ++ + ++E A RE+L R Q+ E
Sbjct: 1038 QLQAAEEAVEKLKATQADMGEKLSCTSNHLAECQAAMLRKDKEGAALREDLERTQK---E 1094
Query: 150 LEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQL 195
LE++ + L Q + + ++ M L ++ DL L
Sbjct: 1095 LEKATTKIQEYYNKLCQEVTNRERNDQKM---LADLDDLNRTKKYL 1137
Score = 35.8 bits (81), Expect = 0.11
Identities = 33/152 (21%), Positives = 70/152 (46%), Gaps = 8/152 (5%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
+ + +E + ++++ Q EVQR + LQA+ + + D++ Q + E L
Sbjct: 761 DNEARELAAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQSQLSMAEAVL 820
Query: 99 KEVRK-----KCAEEAQLISSLKAELTSQESQISTYEE---ELAKAREELSRLQQETAEL 150
+E + K EA + ++ L E + + EE E + EEL LQ+E ++
Sbjct: 821 REHKTLVQQLKEQNEALNRAHVQELLQCSEREGALQEERADEAQQREEELRALQEELSQA 880
Query: 151 EESVESGKAQLEPLQQHLQDSQQEISSMQMKL 182
+ S E + + LQ+ L + + + + +++
Sbjct: 881 KCSSEEAQLEHAELQEQLHRANTDTAELGIQV 912
Score = 33.1 bits (74), Expect = 0.72
Identities = 18/69 (26%), Positives = 42/69 (60%), Gaps = 3/69 (4%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
+E + +DL+ + +++ T+++Q+ +++ +E TN ++ Q++ LD+L+ K
Sbjct: 1079 KEGAALREDLERTQKELEKATTKIQEYYNKLCQEVTNRER---NDQKMLADLDDLNRTKK 1135
Query: 93 QLEEQLKEV 101
LEE+L E+
Sbjct: 1136 YLEERLIEL 1144
Score = 32.7 bits (73), Expect = 0.94
Identities = 25/98 (25%), Positives = 45/98 (45%)
Query: 62 EVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTS 121
+ Q +N + E DE+ + QLE + K++R++ + + L+A ++
Sbjct: 210 QTQEMVSNFDLNSPLNNEALEGFDEMRLELDQLEVREKQLRERMQQLDRENQELRAAVSQ 269
Query: 122 QESQISTYEEELAKAREELSRLQQETAELEESVESGKA 159
Q Q+ T E A E+ RL AEL++ E +A
Sbjct: 270 QGEQLQTERERGRTAAEDNVRLTCLVAELQKQWEVTQA 307
Score = 32.7 bits (73), Expect = 0.94
Identities = 31/145 (21%), Positives = 68/145 (46%), Gaps = 23/145 (15%)
Query: 67 NTNLQKLQAQKQQVQELLDE--LDEQKAQ---LEEQLKEVRKKCAEEAQ----------- 110
N++LQ+ + ++ Q L E LD+ K Q EE+L++ ++ +E Q
Sbjct: 578 NSSLQEAWGKPEEEQRGLQEAQLDDTKVQEGSQEEELRQANRELEKELQNVVGRNQLLEG 637
Query: 111 LISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESV-------ESGKAQLEP 163
+ +L+A+ + + + S + LA E + ++ ++E S+ E+ KAQ+
Sbjct: 638 KLQALQADYQALQQRESAIQGSLASLEAEQASIRHLGDQMEASLLAVRKAKEAMKAQMAE 697
Query: 164 LQQHLQDSQQEISSMQMKLMEMKDL 188
+ LQ + E ++ ++ + + L
Sbjct: 698 KEAILQSKEGECQQLREEVEQCQQL 722
Score = 30.8 bits (68), Expect = 3.6
Identities = 36/163 (22%), Positives = 75/163 (46%), Gaps = 16/163 (9%)
Query: 44 EKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDE-----------LDEQKA 92
++ D + +R E+ + E L++ + Q+Q+ +ELL++ L+ Q A
Sbjct: 464 QEADQLWRRLQELLAHTSSWEEELAELRREKKQQQEEKELLEQEVRSLTRQLQFLETQLA 523
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
Q+ + + ++ ++ + Q L ++ E EL A E+ L + L+E
Sbjct: 524 QVSQHVSDLEEQKKQLIQDKDHLSQQVGMLERLAGPPGPELPVAGEKNEALVPVNSSLQE 583
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQL 195
+ GK + E Q+ LQ++Q + + +Q E ++L N +L
Sbjct: 584 A--WGKPEEE--QRGLQEAQLDDTKVQEGSQE-EELRQANREL 621
>gi|24308179 CTTNBP2 N-terminal like [Homo sapiens]
Length = 639
Score = 62.4 bits (150), Expect = 1e-09
Identities = 50/214 (23%), Positives = 101/214 (47%), Gaps = 19/214 (8%)
Query: 41 DLKEKEDTIKQRTSEVQDLQDEVQRENTNL-QKLQAQKQQVQELLDELDEQKAQLEEQ-- 97
DL+E+ Q T+E D+ +++E L Q+L+ +K QV++ E + +QLEE+
Sbjct: 114 DLEEERQRHAQDTAEGDDVTYMLEKERERLTQQLEFEKSQVKKFEKEQKKLSSQLEEERS 173
Query: 98 ------------LKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAR----EELS 141
K+ K AEE Q L +L ++S++S EEELA R + +
Sbjct: 174 RHKQLSSMLVLECKKATNKAAEEGQKAGELSLKLEKEKSRVSKLEEELAAERKRGLQTEA 233
Query: 142 RLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNWCSSP 201
+++++ +E + E +A+L + + ++E+ S++ + +++ H+S P
Sbjct: 234 QVEKQLSEFDIEREQLRAKLNREENRTKTLKEEMESLKKIVKDLEASHQHSSPNEQLKKP 293
Query: 202 HSILVNGATDYCSLSTSSSETANLNEHVEGQSNL 235
++ AT+ L + +T + SN+
Sbjct: 294 VTVSKGTATEPLMLMSVFCQTESFPAERTHGSNI 327
Score = 31.2 bits (69), Expect = 2.7
Identities = 56/249 (22%), Positives = 102/249 (40%), Gaps = 27/249 (10%)
Query: 38 VEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQK-LQAQKQQVQELLDELDEQKAQLEE 96
+E +L+ ++ I+ ++ +D E + N+ L A ++ + L ++ D +K +
Sbjct: 18 LEGELEARDLVIEALKAQHRDTFIEERYGKYNISDPLMALQRDFETLKEKNDGEKQPVCT 77
Query: 97 Q----LKEVRKKCAE-EAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELE 151
LK V K+C + +++S L A S + + + EE R Q+TAE +
Sbjct: 78 NPLSILKVVMKQCKNMQERMLSQLAA-------AESRHRKVILDLEEERQRHAQDTAEGD 130
Query: 152 ESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNWCSSPHSILVNGATD 211
+ + + E L Q L+ + ++ + K+ + +SQL S H L +
Sbjct: 131 DVTYMLEKERERLTQQLEFEKSQVKKFE------KEQKKLSSQLEEERSRHKQLSSMLVL 184
Query: 212 YCSLSTSSSETANLNEHVEGQSNLE-SEPIHQESPARSSPELLPSGVTDENEVTTAVTEK 270
C +T+ + EGQ E S + +E S E + T A EK
Sbjct: 185 ECKKATNKAAE-------EGQKAGELSLKLEKEKSRVSKLEEELAAERKRGLQTEAQVEK 237
Query: 271 VCSELDNNR 279
SE D R
Sbjct: 238 QLSEFDIER 246
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 62.0 bits (149), Expect = 1e-09
Identities = 25/158 (15%), Positives = 85/158 (53%)
Query: 30 WSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDE 89
W ++ E + +E+ I+++ +V +++++ + Q+ + + + +E + E +E
Sbjct: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEE 619
Query: 90 QKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAE 149
+ + EE+++E +K E+ ++ + ++ QE ++ EE++ + E + R +++ E
Sbjct: 620 KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIRE 679
Query: 150 LEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
E+ + + ++ ++ +Q+ ++++ + K+ E ++
Sbjct: 680 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 717
Score = 58.9 bits (141), Expect = 1e-08
Identities = 25/163 (15%), Positives = 88/163 (53%), Gaps = 8/163 (4%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNL----QKLQAQKQQVQELLDELDEQKAQL 94
E+ ++E+E+ + ++ ++++ +++ Q + + +K++ Q++++QE +++ EQ
Sbjct: 576 EEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQ---- 631
Query: 95 EEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESV 154
EE+++E + E+ + + + ++ QE ++ EE + + E++ +++ E EE +
Sbjct: 632 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKI 691
Query: 155 ESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 197
+ ++ ++ + + ++++ + K+ E ++ + W
Sbjct: 692 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 734
Score = 58.5 bits (140), Expect = 2e-08
Identities = 25/159 (15%), Positives = 89/159 (55%), Gaps = 1/159 (0%)
Query: 30 WSSREK-NNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD 88
W EK E+ +E+E+ + ++ ++++ ++++Q + +++ + + ++ +E+ E +
Sbjct: 587 WRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQE 646
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148
E+ + EE++ E +K E+ + + + ++ QE +I EE++ + E + +++
Sbjct: 647 EKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 706
Query: 149 ELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
E EE + + +++ ++ ++ ++++ +++L + ++
Sbjct: 707 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 745
Score = 57.4 bits (137), Expect = 4e-08
Identities = 27/142 (19%), Positives = 75/142 (52%), Gaps = 1/142 (0%)
Query: 30 WSSREK-NNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD 88
W EK E+ ++E+E+ I+++ ++++ ++ Q + + + + + + +E + E +
Sbjct: 608 WKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 667
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148
E + EE+++E KK E+ + I + + QE ++ EE++ + E++ +++
Sbjct: 668 ETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 727
Query: 149 ELEESVESGKAQLEPLQQHLQD 170
EE + + +L ++ +Q+
Sbjct: 728 RQEEKMWEQEVRLRQQEEKMQE 749
Score = 53.5 bits (127), Expect = 5e-07
Identities = 29/165 (17%), Positives = 89/165 (53%), Gaps = 8/165 (4%)
Query: 30 WSSREK-NNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNL----QKLQAQKQQVQELL 84
W EK E+ + +E+ I+++ + Q+ ++++ ++ + +K+Q Q+++++E
Sbjct: 573 WRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE 632
Query: 85 DELDEQK---AQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELS 141
+++ EQ+ + EE++ E +K E+ + + + + QE +I E+++ + E++
Sbjct: 633 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIR 692
Query: 142 RLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
++ E EE + + ++ ++ +Q+ ++++ + K+ E +
Sbjct: 693 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737
Score = 52.0 bits (123), Expect = 2e-06
Identities = 28/159 (17%), Positives = 83/159 (52%), Gaps = 4/159 (2%)
Query: 30 WSSREK-NNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD 88
W EK E+ ++E+E+ + ++ ++++ Q+E+ RE + + +K +E E +
Sbjct: 513 WRQEEKIREQEEKIREQEEKMWRQEEKIRE-QEEMWREEEKMH--EQEKIWEEEKRQEQE 569
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148
++ + EE+++E +K + + I + + QE ++ EE++ + E++ +++
Sbjct: 570 DKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIR 629
Query: 149 ELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
E EE + + + ++ + + ++++ + K+ E ++
Sbjct: 630 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 668
Score = 50.4 bits (119), Expect = 4e-06
Identities = 31/158 (19%), Positives = 80/158 (50%), Gaps = 4/158 (2%)
Query: 43 KEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVR 102
K+ + I++ T E L E+ R ++L+ + ++QE L ++ +K++++ +KE++
Sbjct: 189 KKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELK 248
Query: 103 KKCAEEAQLI---SSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKA 159
+K E A+L+ L+AE ++ + +L EE + + EE + +
Sbjct: 249 RK-LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE 307
Query: 160 QLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 197
+++ ++ +Q+ +++I + K+ E ++ ++ W
Sbjct: 308 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345
Score = 49.7 bits (117), Expect = 7e-06
Identities = 28/160 (17%), Positives = 90/160 (56%), Gaps = 6/160 (3%)
Query: 30 WSSREK-NNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD 88
W EK E+ ++E+E+ I+++ ++++ +++++R+ + + + + ++ +E++ E +
Sbjct: 303 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 362
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148
E+ + EE + E +K + +++ + ++ E ++ +E+E K RE+ + Q+E
Sbjct: 363 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM--HEQE--KIREQEEKRQEEEK 418
Query: 149 ELE-ESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
E E + +A++ ++ +++ +++I + K+ ++
Sbjct: 419 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE 458
Score = 48.9 bits (115), Expect = 1e-05
Identities = 31/181 (17%), Positives = 91/181 (50%), Gaps = 21/181 (11%)
Query: 30 WSSREKNNVEQDLKEKEDTIKQRTS-----EVQDLQDEVQRENTNLQKLQAQKQQVQELL 84
W EK ++++ +E+ + ++ + Q+ +D++ R+ +++ + + + +E +
Sbjct: 534 WRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKI 593
Query: 85 DELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQ 144
E +E++ + EE++ + +K E+ + I QE +I EE++ + +EE+++ Q
Sbjct: 594 REQEEKRQEQEEKMWKQEEKIREQEEKIQE-------QEEKIREQEEKI-REQEEMTQEQ 645
Query: 145 QE--------TAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLN 196
+E E EE ++ + + ++ +++ +++I + K+ E +++ +
Sbjct: 646 EEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 705
Query: 197 W 197
W
Sbjct: 706 W 706
Score = 47.4 bits (111), Expect = 4e-05
Identities = 36/164 (21%), Positives = 85/164 (51%), Gaps = 11/164 (6%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEV--QDLQDEVQRENTNLQ----KLQAQKQQVQELLDEL 87
EK+ ++ ++KE + +++ + Q LQ E LQ KLQAQ ++ EL + L
Sbjct: 236 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE-NELWNRL 294
Query: 88 DEQKAQL----EEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRL 143
++Q+ + EE+++E +K E+ + I + ++ QE ++ EE + + E++ R
Sbjct: 295 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 354
Query: 144 QQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
++ E EE + + + ++ ++ ++ + + K+ E+++
Sbjct: 355 EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 398
Score = 46.6 bits (109), Expect = 6e-05
Identities = 33/177 (18%), Positives = 87/177 (49%), Gaps = 10/177 (5%)
Query: 30 WSSREK-NNVEQDLKEKEDTI---KQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLD 85
W EK E+ ++E+E + +++ E + +++E +R+ Q +K QE +
Sbjct: 433 WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIW 492
Query: 86 ELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQ 145
E+ + EE++++ +K + + I + ++ QE ++ EE++ + +EE+ R ++
Sbjct: 493 RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI-REQEEMWREEE 551
Query: 146 ETAELEESVESGKAQLEP-----LQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 197
+ E E+ E K Q + ++ +++ ++++ + K+ E ++ + W
Sbjct: 552 KMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMW 608
Score = 46.2 bits (108), Expect = 8e-05
Identities = 27/160 (16%), Positives = 86/160 (53%), Gaps = 3/160 (1%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E+ + EKE+ ++++ + + +++++R+ + + + + ++ +E++ E +E+ +LEE++
Sbjct: 341 EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 400
Query: 99 KEVRK--KCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVES 156
E K + E+ Q ++ + QE + + +E K RE+ +++++ ++ E
Sbjct: 401 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE-EKIREQEEKIREQEKKMWRQEEK 459
Query: 157 GKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLN 196
Q + ++ + Q+E+ + K+ E +++ +++
Sbjct: 460 IHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMH 499
Score = 46.2 bits (108), Expect = 8e-05
Identities = 31/165 (18%), Positives = 88/165 (53%), Gaps = 12/165 (7%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD---EQKAQL- 94
E+ ++ +E+ + ++ ++++L++++ + + Q +K+Q +E + E + EQ+A++
Sbjct: 376 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE--QEEKRQEEEKIREQEKRQEQEAKMW 433
Query: 95 --EEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
EE+++E +K E+ + + + ++ QE EEE + +EE+ R Q+E +E
Sbjct: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQE---KIREEEKRQEQEEMWR-QEEKIHEQE 489
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 197
+ K ++ ++ ++ ++++ + K+ E ++ + W
Sbjct: 490 EIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMW 534
Score = 42.7 bits (99), Expect = 0.001
Identities = 35/144 (24%), Positives = 67/144 (46%), Gaps = 6/144 (4%)
Query: 46 EDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKC 105
ED K + L+ E++ + ++ L QK ++Q L QLE + +++ +
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 106 AEEAQLISSLKAELTS---QESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLE 162
+ + L+ L++ Q+ + Y EEL K R+ LS +E ++ A+L
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL- 226
Query: 163 PLQQHLQDSQQEISSMQMKLMEMK 186
Q+ LQ + E S +Q+ + E+K
Sbjct: 227 --QEKLQLVESEKSEIQLNVKELK 248
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/127 (17%), Positives = 67/127 (52%), Gaps = 4/127 (3%)
Query: 71 QKLQAQKQQVQELLDELDEQKAQL---EEQLKEVRKKCAEEAQLISSLKAELTSQESQIS 127
+K+ Q++++QE +++ EQ+ ++ EE+++E +K + +++ + ++ QE +
Sbjct: 300 EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 359
Query: 128 TYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
EE++ + E + +++ EE + + ++ L++ + + Q++I + K E +
Sbjct: 360 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE-QEKIREQEEKRQEEEK 418
Query: 188 LENHNSQ 194
+ +
Sbjct: 419 IREQEKR 425
Score = 38.1 bits (87), Expect = 0.022
Identities = 40/183 (21%), Positives = 87/183 (47%), Gaps = 19/183 (10%)
Query: 31 SSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQ 90
S + + + ++L+ + TI+ T + +LQ + +++L+ + + + L + +
Sbjct: 114 SHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKF 173
Query: 91 KAQLEEQLKEV---RKKCAEEAQLISSLKAELTSQESQISTYEEEL----AKAREELSRL 143
+LE+ L V +KK + ++ + L+ + + + +EEL AK +E+L +
Sbjct: 174 AGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLV 233
Query: 144 QQETAELEESVESGKAQLE------PLQQ------HLQDSQQEISSMQMKLMEMKDLENH 191
+ E +E++ +V+ K +LE P QQ HL Q +S+ +E +L N
Sbjct: 234 ESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR 293
Query: 192 NSQ 194
+Q
Sbjct: 294 LNQ 296
Score = 37.4 bits (85), Expect = 0.038
Identities = 27/136 (19%), Positives = 76/136 (55%), Gaps = 12/136 (8%)
Query: 43 KEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVR 102
+++E+ + ++ ++Q+ ++++Q + +K++ Q+++++E +++ Q EE + E
Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQEQE---EKIREQEEKIREQEEKMRRQ----EEMMWEKE 348
Query: 103 KKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELS-RLQQETAELEESV---ESGK 158
+K + +++ + ++ QE + EE++ + +EE+ +++ ELEE + E +
Sbjct: 349 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM-RRQEEMMWEKEEKIRELEEKMHEQEKIR 407
Query: 159 AQLEPLQQHLQDSQQE 174
Q E Q+ + +QE
Sbjct: 408 EQEEKRQEEEKIREQE 423
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 61.2 bits (147), Expect = 2e-09
Identities = 23/159 (14%), Positives = 89/159 (55%), Gaps = 1/159 (0%)
Query: 30 WSSREK-NNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD 88
W EK E+ ++E+E+ ++++ ++ + ++++ + +Q+ + + ++ +E + E +
Sbjct: 386 WRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQE 445
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148
++ + EE+++E + E+ + + + ++ QE+++ EE++ + E++ +++
Sbjct: 446 KKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIR 505
Query: 149 ELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
E EE + + ++ ++ + + ++++ + K+ E ++
Sbjct: 506 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 544
Score = 57.4 bits (137), Expect = 4e-08
Identities = 44/260 (16%), Positives = 120/260 (46%), Gaps = 22/260 (8%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQL---- 94
E+ ++E+E+ I+++ ++++ +++++R+ + + + + ++ +E++ E +E+ +L
Sbjct: 294 EEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 353
Query: 95 --EEQLKEVRKKCAEEAQLISSLK-----AELTSQESQISTYEEELAKAREELSRLQQET 147
+E+++E +K EE ++ K A++ QE +I EE++ + E + +++
Sbjct: 354 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKM 413
Query: 148 AELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNWCSSPHSILVN 207
E EE + + +++ ++ ++ +++I + K+ E + E Q +
Sbjct: 414 GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQE--EKIREQEEMMQEQEEKMGE 471
Query: 208 GATDYCSLSTSSSETANLNEHVEGQSNLESEPIHQESPARSSPELL---PSGVTDENEVT 264
C + A + E E E + QE R E + + ++ E
Sbjct: 472 QEGKMC------EQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 525
Query: 265 TAVTEKVCSELDNNRHSKEE 284
EK+C + + + +E+
Sbjct: 526 WEQEEKMCEQEEKMQEQEEK 545
Score = 57.0 bits (136), Expect = 5e-08
Identities = 25/149 (16%), Positives = 86/149 (57%), Gaps = 6/149 (4%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQ- 97
E++++E+E+ ++++ ++++ + +++ + +K++ Q++ +QE +++ EQ+ ++ EQ
Sbjct: 424 EEEMQEQEEKMRRQEEKIREQEKKIREQE---EKIREQEEMMQEQEEKMGEQEGKMCEQE 480
Query: 98 --LKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVE 155
++E +K + + I + ++ QE +I EE + + E++ +++ E EE ++
Sbjct: 481 AKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 540
Query: 156 SGKAQLEPLQQHLQDSQQEISSMQMKLME 184
+ ++ ++ +++ + + + K+ E
Sbjct: 541 EQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 56.6 bits (135), Expect = 6e-08
Identities = 25/155 (16%), Positives = 88/155 (56%), Gaps = 1/155 (0%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
+EK +++ +++E+ I+++ Q+ + ++ R+ +++ + + ++ +E++ E +E+
Sbjct: 356 QEKIREQEEKRQEEEKIREQEKR-QEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMG 414
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
+ EE++ E ++ E+ + + + ++ QE +I EE++ + E + +++ E E
Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEG 474
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
+ +A+++ ++ ++ +++I + K+ E ++
Sbjct: 475 KMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEE 509
Score = 56.2 bits (134), Expect = 8e-08
Identities = 25/148 (16%), Positives = 82/148 (55%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E+ + E+E+ + ++ E+Q+ +++++R+ +++ + + ++ +E + E +E + EE++
Sbjct: 410 EEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 469
Query: 99 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 158
E K E+ + + ++ QE +I E+++ + E++ ++ E EE + +
Sbjct: 470 GEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 529
Query: 159 AQLEPLQQHLQDSQQEISSMQMKLMEMK 186
++ ++ +Q+ ++++ + K+ E +
Sbjct: 530 EKMCEQEEKMQEQEEKMRRQEEKMREQE 557
Score = 55.5 bits (132), Expect = 1e-07
Identities = 29/161 (18%), Positives = 86/161 (53%), Gaps = 10/161 (6%)
Query: 30 WSSREKNNVEQDLK-EKEDTIKQ---RTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLD 85
W EK ++++ EKE+ I++ + E + ++++ ++ + + +K+Q QE
Sbjct: 326 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE--- 382
Query: 86 ELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQ 145
+ + EE+++E +K E+ +++ + ++ QE ++ EEE+ + E++ R ++
Sbjct: 383 ---AKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEE 439
Query: 146 ETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
+ E E+ + + ++ ++ +Q+ ++++ + K+ E +
Sbjct: 440 KIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQE 480
Score = 54.3 bits (129), Expect = 3e-07
Identities = 26/164 (15%), Positives = 88/164 (53%), Gaps = 7/164 (4%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQ 93
EK ++ +E+E + ++ ++++ +++++ + +Q+ + + + +E + E +E+ +
Sbjct: 370 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQE 429
Query: 94 LEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEES 153
EE+++ +K E+ + I + ++ QE + EE++ E+ ++ ++ A+++E
Sbjct: 430 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMG---EQEGKMCEQEAKMQEQ 486
Query: 154 VESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 197
E + Q ++ +++ +++I + K+ E +++ + W
Sbjct: 487 EEKMRRQ----EEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 526
Score = 53.1 bits (126), Expect = 7e-07
Identities = 32/183 (17%), Positives = 95/183 (51%), Gaps = 31/183 (16%)
Query: 36 NNVEQDLKEK----EDTIKQRTSEVQDLQDEVQRENTNLQK------------------L 73
N + Q +EK E+ I++R ++Q+ +++++ + +++ +
Sbjct: 280 NRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 339
Query: 74 QAQKQQVQELLDELDEQ--------KAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQ 125
++++++EL +++ EQ K Q EE+++E K+ +EA++ + ++ QE +
Sbjct: 340 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ-EEKIREQEEK 398
Query: 126 ISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEM 185
I EE + + E++ +++ E EE ++ + ++ ++ +++ +++I + K+ E
Sbjct: 399 IREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 458
Query: 186 KDL 188
+++
Sbjct: 459 EEM 461
Score = 46.6 bits (109), Expect = 6e-05
Identities = 32/159 (20%), Positives = 78/159 (49%), Gaps = 13/159 (8%)
Query: 43 KEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVR 102
K+ + I++ T E L E+ R ++L+ + ++QE L ++ +K++++ +KE++
Sbjct: 177 KKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELK 236
Query: 103 KKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELS-RLQQETAELEESVESGKAQL 161
+K +A+L + Q+ + L K + +S +LQ + E E + Q
Sbjct: 237 RKLE---------RAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQE 287
Query: 162 EPL---QQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 197
E + ++ +Q+ +++I + K+ E ++ ++ W
Sbjct: 288 EKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMW 326
Score = 45.4 bits (106), Expect = 1e-04
Identities = 40/154 (25%), Positives = 79/154 (51%), Gaps = 14/154 (9%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEV--QDLQDEVQRENTNLQ----KLQAQKQQVQELLDEL 87
EK+ ++ ++KE + +++ + Q LQ E LQ KLQAQ ++ EL + L
Sbjct: 224 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE-NELWNRL 282
Query: 88 DEQKAQL----EEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRL 143
++Q+ + EE+++E +K E+ + I + ++ QE + EE++ + E +
Sbjct: 283 NQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK 342
Query: 144 QQETAELEESV---ESGKAQLEPLQQHLQDSQQE 174
+++ ELEE + E + Q E Q+ + +QE
Sbjct: 343 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 376
Score = 43.1 bits (100), Expect = 7e-04
Identities = 35/144 (24%), Positives = 67/144 (46%), Gaps = 6/144 (4%)
Query: 46 EDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKC 105
ED K + L+ E++ + ++ L QK ++Q L QLE + +++ +
Sbjct: 96 EDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 155
Query: 106 AEEAQLISSLKAELTS---QESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLE 162
+ + L+ L++ Q+ + Y EEL K R+ LS +E ++ A+L
Sbjct: 156 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL- 214
Query: 163 PLQQHLQDSQQEISSMQMKLMEMK 186
Q+ LQ + E S +Q+ + E+K
Sbjct: 215 --QEKLQLVESEKSEIQLNVKELK 236
Score = 42.0 bits (97), Expect = 0.002
Identities = 33/175 (18%), Positives = 86/175 (49%), Gaps = 17/175 (9%)
Query: 39 EQDLKEKEDTI-KQRTSEVQDLQDEVQRENTNLQKLQAQKQQV----QELLDELDEQKAQ 93
+Q L+ + D + K+ S LQ +V+ EN +L Q+++ +E + E +E+ +
Sbjct: 248 QQQLQAEADHLGKELQSVSAKLQAQVE-ENELWNRLNQQQEEKMWRQEEKIQEREEKIQE 306
Query: 94 LEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELS-----RLQQETA 148
EE+++E +K + +++ + ++ QE + EE++ + E++ R Q+E
Sbjct: 307 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 366
Query: 149 ELEESV------ESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 197
+ EE + + +A++ ++ +++ +++I + + E ++ + W
Sbjct: 367 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMW 421
Score = 38.5 bits (88), Expect = 0.017
Identities = 40/183 (21%), Positives = 87/183 (47%), Gaps = 19/183 (10%)
Query: 31 SSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQ 90
S + + + ++L+ + TI+ T + +LQ + +++L+ + + + L + +
Sbjct: 102 SHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKF 161
Query: 91 KAQLEEQLKEV---RKKCAEEAQLISSLKAELTSQESQISTYEEEL----AKAREELSRL 143
+LE+ L V +KK + ++ + L+ + + + +EEL AK +E+L +
Sbjct: 162 AGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLV 221
Query: 144 QQETAELEESVESGKAQLE------PLQQ------HLQDSQQEISSMQMKLMEMKDLENH 191
+ E +E++ +V+ K +LE P QQ HL Q +S+ +E +L N
Sbjct: 222 ESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR 281
Query: 192 NSQ 194
+Q
Sbjct: 282 LNQ 284
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 61.2 bits (147), Expect = 2e-09
Identities = 61/296 (20%), Positives = 133/296 (44%), Gaps = 33/296 (11%)
Query: 35 KNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQL 94
+N E + + E+ +K+ Q+L+ ++ + LQ Q ++Q +DEL Q A+
Sbjct: 1029 RNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKK 1088
Query: 95 EEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESV 154
EE+L+ + +E ++ + ++QI+ +E+ + ++ +++ +L E +
Sbjct: 1089 EEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEEL 1148
Query: 155 ESGKAQLE------PLQQHLQDS-QQEISSMQMKLMEMKDLENHNSQLNWCSSPHSILVN 207
E+ K +LE QQ L+ +QE++ ++ L E + +NH +Q+ H+ +
Sbjct: 1149 EALKTELEDTLDTTAAQQELRTKREQEVAELKKALEE--ETKNHEAQIQDMRQRHATALE 1206
Query: 208 GATDYCSLSTSSSETANLNEHVEG--------------QSNLESEPIHQESPARSSPELL 253
++ L + ANL ++ +G +++E H+ + + L
Sbjct: 1207 ELSE--QLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQEL 1264
Query: 254 PSGVTDENEVTTAVTEKVC---SELDN-----NRHSKEEDPFNVDSSSLTGPVADT 301
+ V++ + + + EK +ELDN K+ F D++SL + DT
Sbjct: 1265 HAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDT 1320
Score = 60.1 bits (144), Expect = 6e-09
Identities = 33/163 (20%), Positives = 86/163 (52%), Gaps = 8/163 (4%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
+ K +EQ ++E +++ E+Q +D R N+Q ++AQ ++ + DE +E+K
Sbjct: 1532 KSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKK 1591
Query: 93 --------QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQ 144
+LE +L++ RK+ A ++ +L E+QI + + ++L +LQ
Sbjct: 1592 RLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQ 1651
Query: 145 QETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
+ + + +E +A + + ++S++++ S++ +++++++
Sbjct: 1652 AQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 1694
Score = 57.8 bits (138), Expect = 3e-08
Identities = 42/163 (25%), Positives = 79/163 (48%), Gaps = 27/163 (16%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDE---- 89
E+N + Q+ K+K + +QDL++++ E QKLQ +K + + +++E
Sbjct: 936 ERNQILQNEKKKMQ------AHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILL 989
Query: 90 ----------QKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEEL---AKA 136
+K +E+++ E + AEE + +L QE IS EE L K
Sbjct: 990 LEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKT 1049
Query: 137 REELS----RLQQETAELEESVESGKAQLEPLQQHLQDSQQEI 175
R+EL +L ET +L++ + +AQ++ L+ L ++E+
Sbjct: 1050 RQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEEL 1092
Score = 56.6 bits (135), Expect = 6e-08
Identities = 53/235 (22%), Positives = 104/235 (44%), Gaps = 39/235 (16%)
Query: 38 VEQDLKEKE-------DTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQ----------- 79
+E++L+E++ D ++ T +V L E+ E + QK +QQ
Sbjct: 1741 LEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAK 1800
Query: 80 VQEL-----------LDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQI-- 126
+QEL + L+ + QLEEQL++ K+ A +L+ + +L Q+
Sbjct: 1801 LQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVED 1860
Query: 127 -----STYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMK 181
Y+E++ KA + +L+++ E EE A LQ+ L D+ + + +
Sbjct: 1861 ERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSRE 1920
Query: 182 LMEMKDLENHNSQLNWCSS---PHSILVNGATDYCSLSTSSSETANLNEHVEGQS 233
+ +K+ +++ SS + + GA+ S + S+T+++NE QS
Sbjct: 1921 VSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDDDTESKTSDVNETQPPQS 1975
Score = 51.2 bits (121), Expect = 3e-06
Identities = 43/162 (26%), Positives = 74/162 (45%), Gaps = 21/162 (12%)
Query: 35 KNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQL 94
K +E DLK+ E I+ +DEV ++ L+KLQAQ + Q L+E + ++
Sbjct: 1619 KKKMEIDLKDLEAQIEAANKA----RDEVIKQ---LRKLQAQMKDYQRELEEARASRDEI 1671
Query: 95 EEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELS------------- 141
Q KE KK I L+ EL S E E+E + +E++
Sbjct: 1672 FAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEK 1731
Query: 142 -RLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKL 182
RL+ A+LEE +E ++ +E L + + ++ ++ +L
Sbjct: 1732 RRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAEL 1773
Score = 48.5 bits (114), Expect = 2e-05
Identities = 63/263 (23%), Positives = 116/263 (44%), Gaps = 35/263 (13%)
Query: 40 QDLKEKEDTIKQRTSEV-QDLQDEVQRENTNLQKLQAQKQQ----VQELLDELDE----- 89
++++ + KQ E+ DL+ V+ E Q LQ +K++ +Q+L ++LDE
Sbjct: 907 EEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGAR 966
Query: 90 QKAQLEEQLKEVR-KKCAEEAQLISSLKAELTSQ----ESQISTYEEELAKAREELSRL- 143
QK QLE+ E + KK EE L+ ++ + E +I+ +LA+ E+ L
Sbjct: 967 QKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLA 1026
Query: 144 ----QQET--AELEESV---ESGKAQLEPLQQHLQ----DSQQEISSMQMKLMEMK-DLE 189
+QE ++LEE + E + +LE ++ L D Q +I+ +Q ++ E+K L
Sbjct: 1027 KIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLA 1086
Query: 190 NHNSQLNWC---SSPHSILVNGATDYCSLSTSSSETANLNEHVEGQSNLESEPIHQESPA 246
+L ++ N A + ++ A L E E + ++ Q+
Sbjct: 1087 KKEEELQGALARGDDETLHKNNALKV--VRELQAQIAELQEDFESEKASRNKAEKQKRDL 1144
Query: 247 RSSPELLPSGVTDENEVTTAVTE 269
E L + + D + T A E
Sbjct: 1145 SEELEALKTELEDTLDTTAAQQE 1167
Score = 47.8 bits (112), Expect = 3e-05
Identities = 60/271 (22%), Positives = 119/271 (43%), Gaps = 29/271 (10%)
Query: 35 KNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQ-VQELLDELDEQKAQ 93
+N E+ ++ + ++ +E++D D + Q+L+ +++Q V EL L+E+
Sbjct: 1134 RNKAEKQKRDLSEELEALKTELEDTLDTTAAQ----QELRTKREQEVAELKKALEEETKN 1189
Query: 94 LEEQLKEVRKKCA-------EEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQE 146
E Q++++R++ A E+ + KA L + + T +ELA E+ LQQ
Sbjct: 1190 HEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELAC---EVKVLQQV 1246
Query: 147 TAELEESVESGKAQLEPLQQHLQDSQQ---EISSMQMKLMEMKDLENHNSQLNWCSSPHS 203
AE E + AQ++ L + + + E++ KL +L+N ++ L
Sbjct: 1247 KAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKL--QNELDNVSTLLEEAEKKG- 1303
Query: 204 ILVNGATDYCSLSTSSSETANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDENEV 263
+ A D SL + +T L + Q S I Q ++S L +E E
Sbjct: 1304 --IKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNS---LQEQQEEEEEA 1358
Query: 264 TTAVTEKVC---SELDNNRHSKEEDPFNVDS 291
+ ++V S+L + + ++D ++S
Sbjct: 1359 RKNLEKQVLALQSQLADTKKKVDDDLGTIES 1389
Score = 47.4 bits (111), Expect = 4e-05
Identities = 43/168 (25%), Positives = 81/168 (48%), Gaps = 25/168 (14%)
Query: 31 SSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQ 90
+ R K N+E++ + E K+ EV+ LQ +KL AQ Q++ + E D
Sbjct: 1215 AKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRL 1274
Query: 91 KAQLEEQ--------------LKEVRKKCAEEAQLISSLKAELTSQESQISTYEE----- 131
+ +L E+ L+E KK + A+ +SL+++L Q++Q EE
Sbjct: 1275 RVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQL--QDTQELLQEETRQKL 1332
Query: 132 ----ELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEI 175
+ + EE + LQ++ E EE+ ++ + Q+ LQ L D+++++
Sbjct: 1333 NLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV 1380
Score = 47.4 bits (111), Expect = 4e-05
Identities = 36/176 (20%), Positives = 80/176 (45%), Gaps = 18/176 (10%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQK----LQAQKQQVQELLDELDE 89
E + + +L EK ++ V L +E +++ K L++Q Q QELL E
Sbjct: 1270 EGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETR 1329
Query: 90 QKA-------QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEE-------LAK 135
QK QLEE+ ++++ EE + +L+ ++ + +SQ++ +++ +
Sbjct: 1330 QKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIES 1389
Query: 136 AREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENH 191
E +L ++ L + +E + L++ QQE+ + + L + + ++
Sbjct: 1390 LEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASN 1445
Score = 46.2 bits (108), Expect = 8e-05
Identities = 33/154 (21%), Positives = 71/154 (46%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
+ K +E D KE +K + + + ++ + +Q+L A+ + L EL E+ +
Sbjct: 1224 KNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKAS 1283
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
+L+ +L V E + + S ESQ+ +E L + + L +LEE
Sbjct: 1284 KLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEE 1343
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
S + Q E ++ ++ ++++ ++Q +L + K
Sbjct: 1344 EKNSLQEQQEEEEEARKNLEKQVLALQSQLADTK 1377
Score = 46.2 bits (108), Expect = 8e-05
Identities = 36/142 (25%), Positives = 69/142 (48%), Gaps = 7/142 (4%)
Query: 54 SEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLIS 113
S++QD Q+ +Q E L ++ +Q++E + L EQ+ + EE K + K+ ++
Sbjct: 1315 SQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLA 1374
Query: 114 SLKAELTSQESQISTYEE---ELAKAREELSRLQQETA----ELEESVESGKAQLEPLQQ 166
K ++ I + EE +L K E LS+ +E A +LE++ + +L+ L
Sbjct: 1375 DTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTV 1434
Query: 167 HLQDSQQEISSMQMKLMEMKDL 188
L +Q S+++ K + L
Sbjct: 1435 DLDHQRQVASNLEKKQKKFDQL 1456
Score = 45.8 bits (107), Expect = 1e-04
Identities = 48/185 (25%), Positives = 84/185 (45%), Gaps = 31/185 (16%)
Query: 34 EKNNVEQDLKEKED----------TIKQRTSEVQDLQDEVQRENTNL----QKLQAQKQQ 79
E +NV L+E E +++ + + Q+L E R+ NL ++L+ +K
Sbjct: 1288 ELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNS 1347
Query: 80 VQELLDE-------LDEQKAQLEEQLKEVRKKCAEEAQLISSL---KAELTSQESQISTY 129
+QE +E L++Q L+ QL + +KK ++ I SL K +L +S
Sbjct: 1348 LQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQR 1407
Query: 130 EEELAKAREEL----SRLQQETAELEESVESGK---AQLEPLQQHLQDSQQEISSMQMKL 182
EE A A ++L +RLQQE +L ++ + + LE Q+ E S+ +
Sbjct: 1408 LEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARY 1467
Query: 183 MEMKD 187
E +D
Sbjct: 1468 AEERD 1472
Score = 45.4 bits (106), Expect = 1e-04
Identities = 48/210 (22%), Positives = 86/210 (40%), Gaps = 50/210 (23%)
Query: 35 KNNVEQDL---KEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLD----EL 87
K V+ DL + E+ K+ + + L ++ + KL+ K ++Q+ LD +L
Sbjct: 1377 KKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDL 1436
Query: 88 DEQK---AQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYE----------EELA 134
D Q+ + LE++ K+ + AEE + + E E++ E EE
Sbjct: 1437 DHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEAL 1496
Query: 135 KAREELSR-------------------------LQQETAELEESVESGKAQLEPLQQHLQ 169
+A+EE R L++ LE+ VE + QLE L+ LQ
Sbjct: 1497 EAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQ 1556
Query: 170 DSQQ-----EISSMQMKLMEMKDLENHNSQ 194
++ E++ MK +DL+ + Q
Sbjct: 1557 ATEDAKLRLEVNMQAMKAQFERDLQTRDEQ 1586
Score = 45.1 bits (105), Expect = 2e-04
Identities = 34/160 (21%), Positives = 79/160 (49%), Gaps = 14/160 (8%)
Query: 39 EQDLKEKEDT---IKQRTSEVQDLQDEVQRENTNL--------QKLQAQKQ---QVQELL 84
E++L+ K++ +K++ ++V+ +E++R++ L ++LQA+ + + +E+
Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910
Query: 85 DELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQ 144
L +K +LEE L ++ + EE + L+ E ++ I EE+L + +LQ
Sbjct: 911 ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQ 970
Query: 145 QETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLME 184
E E ++ + ++ L+ +E M+ ++ E
Sbjct: 971 LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAE 1010
Score = 45.1 bits (105), Expect = 2e-04
Identities = 35/161 (21%), Positives = 74/161 (45%), Gaps = 4/161 (2%)
Query: 31 SSREKNNVEQD-LKEKEDTIKQRTSEVQDLQD-EVQRENTNLQKLQAQKQQVQELLDELD 88
S+ EK + D L +E +I R +E +D + E + + T L ++ E +E +
Sbjct: 1444 SNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFE 1503
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148
Q QL ++++ + + + L+ + E Q+ +L + +EL +
Sbjct: 1504 RQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKL 1563
Query: 149 ELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLE 189
LE ++++ KAQ E Q + +E + +K ++++LE
Sbjct: 1564 RLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIK--QVRELE 1602
Score = 44.7 bits (104), Expect = 2e-04
Identities = 35/151 (23%), Positives = 76/151 (50%), Gaps = 11/151 (7%)
Query: 55 EVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD-------EQKAQLEEQLKEVRKKCAE 107
+V ++E+Q ++ L K++ ++ +V+ L+E++ E+K L EQL+ + AE
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAE 905
Query: 108 EAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQH 167
++ + L A+ E + E + + E LQ E +++ ++ + QL+ +
Sbjct: 906 AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGA 965
Query: 168 LQDSQQEISSMQMKLMEMKD----LENHNSQ 194
Q Q E + + K+ +M++ LE+ NS+
Sbjct: 966 RQKLQLEKVTAEAKIKKMEEEILLLEDQNSK 996
Score = 42.0 bits (97), Expect = 0.002
Identities = 38/158 (24%), Positives = 74/158 (46%), Gaps = 15/158 (9%)
Query: 19 ADVLKYSCIVCWSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQ 78
A++L+ + S R + + EQ+ E D I S L DE +R L+A+
Sbjct: 1687 AEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRR-------LEARIA 1739
Query: 79 QVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE 138
Q++E EL+E+++ +E RK + + +L AEL ++ S + +
Sbjct: 1740 QLEE---ELEEEQSNMELLNDRFRKTTLQ----VDTLNAELAAERSAAQKSDNARQQLER 1792
Query: 139 ELSRLQQETAELEESVESG-KAQLEPLQQHLQDSQQEI 175
+ L+ + ELE +V+S KA + L+ + ++++
Sbjct: 1793 QNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQL 1830
Score = 40.8 bits (94), Expect = 0.003
Identities = 35/162 (21%), Positives = 80/162 (49%), Gaps = 28/162 (17%)
Query: 35 KNNVEQDLKEKEDTIKQRT----SEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQ 90
K E+DL+ +++ +++ +V++L+ E++ E A K++++ L +L+ Q
Sbjct: 1573 KAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQ 1632
Query: 91 -----KAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQ 145
KA+ +E +K++RK ++Q+ Y+ EL +AR +
Sbjct: 1633 IEAANKAR-DEVIKQLRK------------------LQAQMKDYQRELEEARASRDEIFA 1673
Query: 146 ETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
++ E E+ ++S +A++ LQ+ L S++ + + E+ D
Sbjct: 1674 QSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELAD 1715
Score = 32.3 bits (72), Expect = 1.2
Identities = 27/125 (21%), Positives = 56/125 (44%), Gaps = 8/125 (6%)
Query: 32 SREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQK----LQAQKQQVQELLDEL 87
+R+K N+ +++ E+ + +Q+ Q+E + NL+K LQ+Q ++ +D+
Sbjct: 1328 TRQKLNLSSRIRQLEE----EKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD 1383
Query: 88 DEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQET 147
LEE K++ K +Q + E + ++EL +L +Q
Sbjct: 1384 LGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVA 1443
Query: 148 AELEE 152
+ LE+
Sbjct: 1444 SNLEK 1448
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 60.5 bits (145), Expect = 4e-09
Identities = 31/172 (18%), Positives = 86/172 (50%), Gaps = 4/172 (2%)
Query: 30 WSSREKNNVEQDLKEKEDTIKQ----RTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLD 85
W EK + ++ ++E+E +Q R E Q+E+ R+ + + + + ++ +E +
Sbjct: 501 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMW 560
Query: 86 ELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQ 145
+E+ EE+++E +K + + I + ++ QE +I EE + E++ ++
Sbjct: 561 RQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 620
Query: 146 ETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 197
+ E EE ++ + ++ ++ +++ +++I + K+ E +++ + W
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 672
Score = 60.5 bits (145), Expect = 4e-09
Identities = 23/158 (14%), Positives = 87/158 (55%)
Query: 30 WSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDE 89
W EK ++++ +++ I ++ +++ ++++ R+ + + + ++ +E + +E
Sbjct: 526 WRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEE 585
Query: 90 QKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAE 149
+ + EE+++E +K E+ ++ + ++ QE ++ EE++ + E++ R +++ E
Sbjct: 586 KIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE 645
Query: 150 LEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
E+ + + ++ ++ +Q+ ++++ + K+ E ++
Sbjct: 646 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 683
Score = 60.1 bits (144), Expect = 6e-09
Identities = 25/139 (17%), Positives = 77/139 (55%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E+ ++E+E+ I+++ ++++ ++ Q + + + + + + +E + E +E+ + EE++
Sbjct: 584 EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Query: 99 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 158
+E KK E+ + I + + QE ++ EE++ + E++ +++ EE + +
Sbjct: 644 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 703
Query: 159 AQLEPLQQHLQDSQQEISS 177
+L ++ +Q+ Q+ + +
Sbjct: 704 VRLRQQEEKMQEHQEHLEA 722
Score = 58.2 bits (139), Expect = 2e-08
Identities = 26/168 (15%), Positives = 93/168 (55%), Gaps = 9/168 (5%)
Query: 30 WSSREK-NNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD 88
W EK ++ E+ ++E+E+ + ++ ++++ +++++ + +++ + Q+ +E + E +
Sbjct: 560 WRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQE 619
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148
E+ + EE+++E +K + + ++ QE +I EE++ + E + +++
Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEE-------KIREQEKKIREQEEKIREQEEMMQEQEEKMW 672
Query: 149 ELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD-LENHNSQL 195
E EE + + +++ ++ ++ ++++ +++L + ++ ++ H L
Sbjct: 673 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720
Score = 56.6 bits (135), Expect = 6e-08
Identities = 24/168 (14%), Positives = 86/168 (51%), Gaps = 6/168 (3%)
Query: 30 WSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDE 89
W +EK + E+E+ I+++ ++ ++++ + +++ + + + +E + E +E
Sbjct: 539 WRQKEK------IHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEE 592
Query: 90 QKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAE 149
+ + EE+++E + E+ + + + ++ QE ++ EE++ + E++ +++ E
Sbjct: 593 KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIRE 652
Query: 150 LEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 197
EE + + ++ ++ + + ++++ + K+ E ++ + W
Sbjct: 653 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 700
Score = 51.2 bits (121), Expect = 3e-06
Identities = 35/159 (22%), Positives = 80/159 (50%), Gaps = 8/159 (5%)
Query: 30 WSSREK-NNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD 88
W EK +E+ + E+E K R E + ++E RE Q+ +A+ + +E + E +
Sbjct: 434 WEKEEKIRELEEKMHEQE---KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 490
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148
E+ + EE++ +K E+ ++ + E QE + +EE + +EE+ R +++
Sbjct: 491 EKIREQEEKMWRQEEKIHEQEKI----REEEKRQEQEEMWRQEEKIREQEEIWRQKEKIH 546
Query: 149 ELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
E EE + + ++ ++ + D +++I + K+ ++
Sbjct: 547 EQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEE 585
Score = 50.4 bits (119), Expect = 4e-06
Identities = 31/158 (19%), Positives = 80/158 (50%), Gaps = 4/158 (2%)
Query: 43 KEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVR 102
K+ + I++ T E L E+ R ++L+ + ++QE L ++ +K++++ +KE++
Sbjct: 250 KKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELK 309
Query: 103 KKCAEEAQLI---SSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKA 159
+K E A+L+ L+AE ++ + +L EE + + EE + +
Sbjct: 310 RK-LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE 368
Query: 160 QLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 197
+++ ++ +Q+ +++I + K+ E ++ ++ W
Sbjct: 369 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 406
Score = 48.9 bits (115), Expect = 1e-05
Identities = 30/165 (18%), Positives = 85/165 (51%), Gaps = 10/165 (6%)
Query: 30 WSSREK-NNVEQDLKEKEDTI---KQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLD 85
W EK E+ ++E+E+ + +++ E + +++E +R+ Q +K + QE
Sbjct: 480 WRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE--- 536
Query: 86 ELDEQKAQLEEQLKEVRK---KCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSR 142
E+ QK ++ EQ +++RK K + + + + ++ QE ++ EE++ + E++
Sbjct: 537 EIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIRE 596
Query: 143 LQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
+++ E EE + + ++ ++ + + ++++ + K+ ++
Sbjct: 597 QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEE 641
Score = 47.8 bits (112), Expect = 3e-05
Identities = 26/160 (16%), Positives = 87/160 (54%), Gaps = 3/160 (1%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E+ ++E+E+ ++++ + + +++++R+ + + + + ++ +E++ E +E+ +LEE++
Sbjct: 388 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 447
Query: 99 KEVRK--KCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVES 156
E K + E+ Q ++ + QE + + +E K RE+ +++++ ++ E
Sbjct: 448 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE-EKIREQEEKIREQEEKMWRQEEK 506
Query: 157 GKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLN 196
Q + ++ + Q+E+ + K+ E +++ +++
Sbjct: 507 IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIH 546
Score = 46.2 bits (108), Expect = 8e-05
Identities = 35/167 (20%), Positives = 83/167 (49%), Gaps = 10/167 (5%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEV--QDLQDEVQRENTNLQ----KLQAQKQQVQELLDEL 87
EK+ ++ ++KE + +++ + Q LQ E LQ KLQAQ ++ EL + L
Sbjct: 297 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE-NELWNRL 355
Query: 88 DEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQET 147
++Q+ EE++ +K E + I + ++ QE +I EE++ + E + +++
Sbjct: 356 NQQQ---EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 412
Query: 148 AELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQ 194
EE + + ++ ++ + + +++I ++ K+ E + + +
Sbjct: 413 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 459
Score = 44.3 bits (103), Expect = 3e-04
Identities = 28/166 (16%), Positives = 87/166 (52%), Gaps = 11/166 (6%)
Query: 30 WSSREK-NNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD 88
W EK E+ ++E+E+ I+++ ++++ +++++R+ + + + + ++ +E++ E
Sbjct: 364 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE-K 422
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148
E+K + +E++ E+ + I L+ ++ QE E+E + EE R Q++
Sbjct: 423 EEKMRRQEEM------MWEKEEKIRELEEKMHEQE---KIREQEEKRQEEEKIREQEKRQ 473
Query: 149 ELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQ 194
E E + + ++ ++ +++ ++++ + K+ E + + +
Sbjct: 474 EQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKR 519
Score = 42.7 bits (99), Expect = 0.001
Identities = 35/144 (24%), Positives = 67/144 (46%), Gaps = 6/144 (4%)
Query: 46 EDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKC 105
ED K + L+ E++ + ++ L QK ++Q L QLE + +++ +
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 228
Query: 106 AEEAQLISSLKAELTS---QESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLE 162
+ + L+ L++ Q+ + Y EEL K R+ LS +E ++ A+L
Sbjct: 229 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL- 287
Query: 163 PLQQHLQDSQQEISSMQMKLMEMK 186
Q+ LQ + E S +Q+ + E+K
Sbjct: 288 --QEKLQLVESEKSEIQLNVKELK 309
Score = 39.3 bits (90), Expect = 0.010
Identities = 26/156 (16%), Positives = 82/156 (52%), Gaps = 12/156 (7%)
Query: 43 KEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLK-EV 101
+++E+ + ++ ++Q+ ++++Q + +K++ Q+++++E E+K + +E++ E
Sbjct: 357 QQQEEKMWRQEEKIQEWEEKIQEQE---EKIREQEEKIRE-----QEEKMRRQEEMMWEK 408
Query: 102 RKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQL 161
+K + +++ + ++ QE + EE++ + E++ Q++ E EE + +
Sbjct: 409 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE-QEKIREQEEKRQEEEKIR 467
Query: 162 EPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 197
E Q+ Q+ + ++ + K+ E ++ + W
Sbjct: 468 E--QEKRQEQEAKMWRQEEKIREQEEKIREQEEKMW 501
Score = 38.1 bits (87), Expect = 0.022
Identities = 40/183 (21%), Positives = 87/183 (47%), Gaps = 19/183 (10%)
Query: 31 SSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQ 90
S + + + ++L+ + TI+ T + +LQ + +++L+ + + + L + +
Sbjct: 175 SHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKF 234
Query: 91 KAQLEEQLKEV---RKKCAEEAQLISSLKAELTSQESQISTYEEEL----AKAREELSRL 143
+LE+ L V +KK + ++ + L+ + + + +EEL AK +E+L +
Sbjct: 235 AGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLV 294
Query: 144 QQETAELEESVESGKAQLE------PLQQ------HLQDSQQEISSMQMKLMEMKDLENH 191
+ E +E++ +V+ K +LE P QQ HL Q +S+ +E +L N
Sbjct: 295 ESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR 354
Query: 192 NSQ 194
+Q
Sbjct: 355 LNQ 357
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 60.1 bits (144), Expect = 6e-09
Identities = 33/158 (20%), Positives = 83/158 (52%), Gaps = 5/158 (3%)
Query: 43 KEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVR 102
K+ + I++ T E L E+ R ++L+ + ++QE L + +K++++ +KE++
Sbjct: 193 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELK 252
Query: 103 KKCAEEAQLI-----SSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESG 157
+K L+ ++L+ E+ QE ++ E+++ K E++ R ++ E E +
Sbjct: 253 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQ 312
Query: 158 KAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQL 195
+ ++ ++ L++ ++E+ + +L E K+L Q+
Sbjct: 313 EEKMWRQEKRLREQEKELREQEKELREQKELREQEEQM 350
Score = 58.9 bits (141), Expect = 1e-08
Identities = 33/184 (17%), Positives = 91/184 (49%), Gaps = 26/184 (14%)
Query: 30 WSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQ----KLQAQKQQVQELLD 85
W EK E+ ++E+E +++ +++ ++++Q + +Q K+ Q++++QE +
Sbjct: 579 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEE 638
Query: 86 ELDEQKAQLEEQ----------------------LKEVRKKCAEEAQLISSLKAELTSQE 123
++ EQ+ ++ EQ ++E K +E ++ K E +QE
Sbjct: 639 KMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQE 698
Query: 124 SQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLM 183
+ T+++E + E + +++ E EE + + +++ ++ +Q+ ++E+ + K+
Sbjct: 699 QEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMW 758
Query: 184 EMKD 187
E ++
Sbjct: 759 EQEE 762
Score = 56.2 bits (134), Expect = 8e-08
Identities = 37/176 (21%), Positives = 87/176 (49%), Gaps = 15/176 (8%)
Query: 30 WSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDE 89
W +K ++ ++E+ED + ++ +++D + ++ + ++K K Q QE E
Sbjct: 527 WGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEK----KTQEQEKKTWDQE 582
Query: 90 QKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAE 149
+K + EE+++E KK EE +++ + ++ QE ++ EE++ + E++ +++ E
Sbjct: 583 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWE 642
Query: 150 LEESV----------ESGKAQLEPLQQHLQDSQQE-ISSMQMKLMEMKDLENHNSQ 194
EE + + Q E L +H + +QE + + K+ E + +E +
Sbjct: 643 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQE 698
Score = 54.3 bits (129), Expect = 3e-07
Identities = 31/160 (19%), Positives = 88/160 (55%), Gaps = 7/160 (4%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
+E E+ ++E+E+ + ++ ++++ ++++ R+ L + + Q ++ ++ + + +E+
Sbjct: 341 KELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 400
Query: 93 QLEEQLKEVRKKCAEEAQL---ISSLKAELTSQESQISTYEEELAKAREELSRLQQETAE 149
+ +E+L+E ++ E+ ++ + ++ E QE + T ++E EE R+++ +
Sbjct: 401 EQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEE--RIREREKK 458
Query: 150 LEESVESGKAQLEPLQQHLQD--SQQEISSMQMKLMEMKD 187
+ E E+ + Q E +Q+ ++ Q+E Q +L E K+
Sbjct: 459 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE 498
Score = 50.4 bits (119), Expect = 4e-06
Identities = 31/153 (20%), Positives = 82/153 (53%), Gaps = 9/153 (5%)
Query: 40 QDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDE-----LDEQKAQL 94
++LK+K ++++ + + E+Q N+++L+ + ++ + LL + L E+ +
Sbjct: 221 EELKKKNAELQEKLPLAESEKSEIQ---LNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ 277
Query: 95 EEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESV 154
EE+L+E KK ++ + + + L QE ++ EE++ + + L ++E E E+ +
Sbjct: 278 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKEL 337
Query: 155 ESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
K +L ++ +Q+ ++++ + K+ E ++
Sbjct: 338 REQK-ELREQEEQMQEQEEKMWEQEEKMREQEE 369
Score = 48.5 bits (114), Expect = 2e-05
Identities = 34/161 (21%), Positives = 80/161 (49%), Gaps = 11/161 (6%)
Query: 30 WSSREK-NNVEQDLKEKEDTIKQRTSEVQDL---QDEVQRENTNLQKLQAQKQQVQELLD 85
W EK + EQ + ++E+ ++++T E + Q+E RE +++ + + ++ +E++
Sbjct: 547 WEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR 606
Query: 86 ELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQ 145
E EE+++E +K E+ + + + ++ QE ++ EE++ + E++ Q+
Sbjct: 607 EQ-------EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659
Query: 146 ETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
+ E+ E K Q + Q ++ E M+ K E +
Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQE 700
Score = 48.1 bits (113), Expect = 2e-05
Identities = 34/163 (20%), Positives = 89/163 (54%), Gaps = 14/163 (8%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQ 93
EK+ ++ ++KE +K++ + L +VQ NT +++ Q+++++E ++ +Q+ +
Sbjct: 240 EKSEIQLNVKE----LKRKLERAKFLLPQVQT-NTLQEEMWRQEEELREQEKKIRKQEEK 294
Query: 94 L---EEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEEL---AKAREELSRLQQET 147
+ EE+L+E K E+ + + + L QE ++ E+EL + RE+ ++Q++
Sbjct: 295 MWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQE 354
Query: 148 AELEESVESGKAQLEPL---QQHLQDSQQEISSMQMKLMEMKD 187
++ E E + Q E + ++ L + ++++ + K+ + ++
Sbjct: 355 EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 397
Score = 47.8 bits (112), Expect = 3e-05
Identities = 29/167 (17%), Positives = 86/167 (51%), Gaps = 7/167 (4%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQA----QKQQVQELLDELD 88
++ EQ ++++E+ + ++ +++ ++ ++ + ++++ +K Q QE
Sbjct: 383 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQ 442
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148
E+K Q EE+++E KK EE + + + ++ QE + +E+E + +++ Q+E
Sbjct: 443 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM--WEQEEKEWQQQRLPEQKEKL 500
Query: 149 ELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQL 195
+E ++ + ++ ++ ++D Q+E+ + K+ + + Q+
Sbjct: 501 WEQEKMQEQEEKIWEQEEKIRD-QEEMWGQEKKMWRQEKMREQEDQM 546
Score = 47.4 bits (111), Expect = 4e-05
Identities = 31/170 (18%), Positives = 86/170 (50%), Gaps = 10/170 (5%)
Query: 30 WSSREK-NNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQK---LQAQKQQVQELLD 85
W E+ E ++E+E+ + ++ +++ + E++ + L++ L+ Q++Q+QE +
Sbjct: 296 WRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEE 355
Query: 86 ELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQ 145
++ EQ EE+++E +K + + + + ++ QE ++ EE + + E L ++
Sbjct: 356 KMWEQ----EEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 411
Query: 146 ETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQL 195
E E+ E + E ++ +Q+ +++ + K+ E + + ++
Sbjct: 412 RMREQEKMWEQVEKMRE--EKKMQEQEKKTRDQEEKMQEEERIREREKKM 459
Score = 46.2 bits (108), Expect = 8e-05
Identities = 41/163 (25%), Positives = 86/163 (52%), Gaps = 15/163 (9%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
+EK +Q+ +E+++++R ++++ ++E+ RE +K+Q Q++++QE +E+ EQ+
Sbjct: 699 QEKKTWDQEKMREEESMREREKKMRE-EEEMMREQE--EKMQEQEEKMQEQEEEMWEQEE 755
Query: 93 QLEEQ---------LKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRL 143
++ EQ L E ++K E ++ K + QE ++ EE++ + +EE R
Sbjct: 756 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK--IWEQEEKMRDQEEKM-RGQEEKMRG 812
Query: 144 QQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
Q+E +E G+ + Q+ Q+E Q + ME K
Sbjct: 813 QEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEK 855
Score = 42.7 bits (99), Expect = 0.001
Identities = 33/180 (18%), Positives = 82/180 (45%), Gaps = 15/180 (8%)
Query: 30 WSSREKNNVEQDLKEKEDTIKQRTSEVQDLQ-----DEVQRENTNLQKLQAQKQQVQELL 84
W EK E+ ++E+E + + ++Q+ + ++ RE + Q +K Q QE
Sbjct: 420 WEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 479
Query: 85 DELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEE---------ELAK 135
E+K +++L E ++K E+ ++ + ++ QE +I EE K
Sbjct: 480 MWEQEEKEWQQQRLPEQKEKLWEQEKM-QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 538
Query: 136 AREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQL 195
RE+ ++ ++ ++ + + Q E +++ Q+ +++ + K+ E + + ++
Sbjct: 539 MREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKM 598
Score = 42.7 bits (99), Expect = 0.001
Identities = 32/181 (17%), Positives = 86/181 (47%), Gaps = 16/181 (8%)
Query: 30 WSSREKNNVEQDLKEKEDTI-----KQRTSEVQDLQDEVQRENTNLQKLQAQ-------- 76
W EK +Q L E+++ + Q ++Q+ ++++ + +K Q Q
Sbjct: 648 WEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQE 707
Query: 77 KQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKA 136
K + +E + E +++ + EE ++E +K E+ + + + E+ QE ++ EE++ +
Sbjct: 708 KMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWE- 766
Query: 137 REELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLN 196
++ L +++ E E+ E K + ++ ++D ++++ + K+ ++ +
Sbjct: 767 QQRLPEQKEKLWEHEKMQEQEK--IWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKM 824
Query: 197 W 197
W
Sbjct: 825 W 825
Score = 39.7 bits (91), Expect = 0.008
Identities = 28/174 (16%), Positives = 87/174 (50%), Gaps = 24/174 (13%)
Query: 33 REKNNVEQD--LKEKEDTIKQRTSEVQDLQDEVQRENTNL----------QKLQAQKQ-- 78
REK E++ ++E+E+ ++++ ++Q+ ++E+ + + Q+L QK+
Sbjct: 718 REKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKL 777
Query: 79 ------QVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEE 132
Q QE + E +E+ EE+++ +K + + + + ++ QE ++ EE+
Sbjct: 778 WEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEK 837
Query: 133 LAKAREEL----SRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKL 182
+ E++ +++++ EE + + ++ ++ +++ ++++ + K+
Sbjct: 838 MWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 60.1 bits (144), Expect = 6e-09
Identities = 42/183 (22%), Positives = 86/183 (46%), Gaps = 21/183 (11%)
Query: 30 WSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDE--- 86
W ++ + + Q +E E+ K+ +QD ++ V+ N L+ KQ++Q +++
Sbjct: 1375 WRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMI 1434
Query: 87 -----------LDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQI----STYEE 131
LD+++ ++ L E ++KC E + + + E S +++ + YEE
Sbjct: 1435 DVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEE 1494
Query: 132 ---ELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDL 188
+L + E LQQE ++L E + G ++ L++ + +QE S +Q L E +
Sbjct: 1495 SLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEAS 1554
Query: 189 ENH 191
H
Sbjct: 1555 LEH 1557
Score = 52.0 bits (123), Expect = 2e-06
Identities = 50/189 (26%), Positives = 83/189 (43%), Gaps = 32/189 (16%)
Query: 31 SSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQ 90
+ E E KE E+ + E DLQ +VQ E +L +E D+L +
Sbjct: 863 TKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLA-------DAEERCDQLIKT 915
Query: 91 KAQLEEQLKEVRKKCAEEAQL--------------ISSLKAELTSQESQISTYEEELAKA 136
K QLE ++KEV ++ +E ++ S LK ++ E ++ E+E
Sbjct: 916 KIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 975
Query: 137 REELSRLQQETAELEESV----ESGKAQLEPLQQHLQDSQQE------ISSMQMKL-MEM 185
++ L +E A L+E++ + KA E QQ L D Q E ++ ++KL ++
Sbjct: 976 ENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQV 1035
Query: 186 KDLENHNSQ 194
DLE Q
Sbjct: 1036 DDLEGSLEQ 1044
Score = 48.5 bits (114), Expect = 2e-05
Identities = 41/178 (23%), Positives = 84/178 (47%), Gaps = 24/178 (13%)
Query: 32 SREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQK 91
S+ K N+E+ + ED + + ++ ++ Q + +LQ + + LDE D
Sbjct: 1243 SKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLV 1302
Query: 92 AQLE-------EQLKEVRKKCAEEAQLISSLKAELTSQESQI----STYEEE-------- 132
+QL +Q++E++++ EE + S+L L S YEEE
Sbjct: 1303 SQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQ 1362
Query: 133 --LAKAREELS--RLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
++KA E++ R + ET ++ + E +A+ + L Q LQD+++ + ++ K ++
Sbjct: 1363 RAMSKANSEVAQWRTKYETDAIQRTEELEEAK-KKLAQRLQDAEEHVEAVNAKCASLE 1419
Score = 48.1 bits (113), Expect = 2e-05
Identities = 54/268 (20%), Positives = 117/268 (43%), Gaps = 37/268 (13%)
Query: 32 SREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQK 91
++ K +EQ + + E +++Q DL+ ++ +L+ Q ++ +LDE+
Sbjct: 1025 TKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKL 1084
Query: 92 AQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEEL-------AKAREELSRLQ 144
+ E ++ ++ K +E L L+ ++ +++I EEE+ AKA ++ S L
Sbjct: 1085 KKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS 1144
Query: 145 QETAELEESVESG----KAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNWCSS 200
+E E+ E +E AQ+E + ++E +M+ +DLE
Sbjct: 1145 RELEEISERLEEAGGATSAQIE------MNKKREAEFQKMR----RDLE----------- 1183
Query: 201 PHSILVNGATDYCSLSTSSSETANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDE 260
+ L + AT + A L E ++ ++ + ++S + + L S +
Sbjct: 1184 -EATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETV 1242
Query: 261 NEVTTAVTEKVCSELDNNR---HSKEED 285
++ + EK+C L++ +KEE+
Sbjct: 1243 SKAKGNL-EKMCRALEDQLSEIKTKEEE 1269
Score = 47.4 bits (111), Expect = 4e-05
Identities = 37/188 (19%), Positives = 86/188 (45%), Gaps = 28/188 (14%)
Query: 37 NVEQDLKEKEDTIKQRTSEVQDLQ-------DEVQRENTNLQKLQAQKQQVQELLDELD- 88
N+ +++ ++TI + T E + LQ D++Q E + L K ++++ +D+L+
Sbjct: 981 NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEG 1040
Query: 89 --EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQI---------------STYEE 131
EQ+ ++ L+ ++K + +L ++ + + Q+ S E+
Sbjct: 1041 SLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIED 1100
Query: 132 ELA---KAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDL 188
E A + ++++ LQ ELEE +E+ +A ++ D +E+ + +L E
Sbjct: 1101 EQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1160
Query: 189 ENHNSQLN 196
+ ++N
Sbjct: 1161 TSAQIEMN 1168
Score = 47.4 bits (111), Expect = 4e-05
Identities = 40/170 (23%), Positives = 85/170 (50%), Gaps = 18/170 (10%)
Query: 31 SSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQ 90
S+ + N +Q L EK +K++ E+ LQ +++ E +LQ + +++Q ++EL+E+
Sbjct: 1069 STMDIENDKQQLDEK---LKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEE 1125
Query: 91 -------KAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREEL--S 141
+A+ E+Q ++ ++ E ++ + ++Q E E K R +L +
Sbjct: 1126 IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1185
Query: 142 RLQQETA------ELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEM 185
LQ E + +SV Q++ LQ+ Q ++E S M+M++ ++
Sbjct: 1186 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDL 1235
Score = 47.0 bits (110), Expect = 5e-05
Identities = 35/162 (21%), Positives = 75/162 (46%), Gaps = 18/162 (11%)
Query: 38 VEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKL-----------QAQKQQVQELLDE 86
V+Q L++++ +K ++ + V + NL+K+ + ++++ Q L+++
Sbjct: 1217 VKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLIND 1276
Query: 87 LDEQKAQLEEQLKEVRKKCAEEAQLISSL---KAELTSQESQISTYEEELAKAREELSRL 143
L Q+A+L+ + E ++ E+ L+S L K T Q ++ EE KA+ L+
Sbjct: 1277 LTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHA 1336
Query: 144 QQETAE----LEESVESGKAQLEPLQQHLQDSQQEISSMQMK 181
Q + L E E + LQ+ + + E++ + K
Sbjct: 1337 LQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTK 1378
Score = 46.6 bits (109), Expect = 6e-05
Identities = 48/257 (18%), Positives = 106/257 (41%), Gaps = 47/257 (18%)
Query: 50 KQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDE--------------LDEQKAQLE 95
K+ V +L +++ QKL+ +K +++ +D+ L++ LE
Sbjct: 1198 KKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALE 1257
Query: 96 EQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVE 155
+QL E++ K E+ +LI+ L A+ +++ Y +L + +S+L + + +E
Sbjct: 1258 DQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIE 1317
Query: 156 SGKAQLE-------PLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNWCSSPHSILVNG 208
K QLE L LQ S+ + ++ + E ++ + +
Sbjct: 1318 ELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQR-------------- 1363
Query: 209 ATDYCSLSTSSSETANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDENEVTTAVT 268
++S ++SE A + ++ E++ I + + + L + D E AV
Sbjct: 1364 -----AMSKANSEVA------QWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVN 1412
Query: 269 EKVCSELDNNRHSKEED 285
K C+ L+ + + +
Sbjct: 1413 AK-CASLEKTKQRLQNE 1428
Score = 45.4 bits (106), Expect = 1e-04
Identities = 34/153 (22%), Positives = 69/153 (45%), Gaps = 8/153 (5%)
Query: 33 REKNNVEQDLKEKED--------TIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELL 84
R K N+EQ +K+ + +K ++Q L+ V+ ++ Q + + + L
Sbjct: 1785 RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGL 1844
Query: 85 DELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQ 144
+ + + +L Q +E RK L+ L+A++ S + Q EE+ + R+Q
Sbjct: 1845 RKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQ 1904
Query: 145 QETAELEESVESGKAQLEPLQQHLQDSQQEISS 177
E E EE + ++Q+ L+ ++ +I S
Sbjct: 1905 HELEEAEERADIAESQVNKLRVKSREVHTKIIS 1937
Score = 43.5 bits (101), Expect = 5e-04
Identities = 41/169 (24%), Positives = 84/169 (49%), Gaps = 21/169 (12%)
Query: 32 SREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQK 91
+ ++ + +L K+ ++ SE++ D+++ L K++ +K + + L E+
Sbjct: 930 AEDEEEINAELTAKKRKLEDECSELKKDIDDLE---LTLAKVEKEKHATENKVKNLTEEM 986
Query: 92 AQLEEQLKEV--RKKCAEEA--QLISSLKAELTSQESQISTYEEELAKAREELSRLQQET 147
A L+E + ++ KK +EA Q + L+AE E +++T L KA+ +L+Q+
Sbjct: 987 AGLDETIAKLTKEKKALQEAHQQTLDDLQAE----EDKVNT----LTKAK---IKLEQQV 1035
Query: 148 AELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLN 196
+LE S+E K L++ + + ++ Q M D+EN QL+
Sbjct: 1036 DDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTM---DIENDKQQLD 1081
Score = 43.5 bits (101), Expect = 5e-04
Identities = 43/186 (23%), Positives = 89/186 (47%), Gaps = 26/186 (13%)
Query: 30 WSSR-EKNNVEQDLKEKEDT--------IKQRTSEVQDLQDEVQRENTNLQKLQAQKQQV 80
W + E+ + E + +KE IK E D + ++REN NLQ Q++
Sbjct: 1460 WKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQ------QEI 1513
Query: 81 QELLDELDE---QKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAR 137
+L +++ E + +LE+ K+V ++ +E + +A L +E +I + EL + +
Sbjct: 1514 SDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVK 1573
Query: 138 EELSR-LQQETAELEES-------VESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLE 189
E+ R + ++ E+++ VES ++ L+ + D+ + M+ L EM+
Sbjct: 1574 SEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQL 1633
Query: 190 NHNSQL 195
NH +++
Sbjct: 1634 NHANRM 1639
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/187 (22%), Positives = 91/187 (48%), Gaps = 33/187 (17%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQ-AQKQQVQELLD------------ 85
++DLKE+ +++R + LQ E++ L++ + ++K QELLD
Sbjct: 1668 QEDLKEQLAMVERRANL---LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQN 1724
Query: 86 -ELDEQKAQLEEQLKEVR-------------KKCAEEAQLISSLKAELTSQESQISTYEE 131
L K +LE + +++ ++ A++A +++ AE +E S + E
Sbjct: 1725 TSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1784
Query: 132 ELAKAREE-LSRLQQETAELEE-SVESGKAQLEPLQQHLQDSQQEISSMQMKLME-MKDL 188
+ K E+ + LQ E E+ +++ GK Q++ L+ +++ + E+ S Q + +E +K L
Sbjct: 1785 RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGL 1844
Query: 189 ENHNSQL 195
H ++
Sbjct: 1845 RKHERKV 1851
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 10/157 (6%)
Query: 35 KNNVEQDLKEKEDTIKQRTSEVQDLQD-EVQRENTN---------LQKLQAQKQQVQELL 84
++ ++ +++ + D I+ + DL + E+Q + N + QA + Q L
Sbjct: 1602 QSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHL 1661
Query: 85 DELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQ 144
D+ + L+EQL V ++ I L+A L E E+EL A E + L
Sbjct: 1662 DDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLH 1721
Query: 145 QETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMK 181
+ L + + + + +Q ++D QE + + K
Sbjct: 1722 TQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEK 1758
Score = 40.4 bits (93), Expect = 0.005
Identities = 30/162 (18%), Positives = 75/162 (46%), Gaps = 11/162 (6%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
R N + LK+ + + +DL++++ LQA+ ++++ L++ + +
Sbjct: 1645 RNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRK 1704
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
E++L + +E QL+ + L + + ++ T ++++ + E+ + QE EE
Sbjct: 1705 IAEQELLD----ASERVQLLHTQNTSLINTKKKLET---DISQIQGEMEDIIQEARNAEE 1757
Query: 153 SVESGKAQLEPLQQHL---QDSQQEISSMQMKLME-MKDLEN 190
+ + + L QD+ + M+ L + +KDL++
Sbjct: 1758 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1799
Score = 32.7 bits (73), Expect = 0.94
Identities = 22/108 (20%), Positives = 53/108 (49%), Gaps = 9/108 (8%)
Query: 32 SREKNNVE--QDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDE 89
S +K NVE + L++ E +K+ T + ++ + + R + KLQA+ + + +E +E
Sbjct: 1832 SEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEE 1891
Query: 90 QK-------AQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYE 130
Q +++ +L+E ++ ++ L+ + ++I + E
Sbjct: 1892 QSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKIISEE 1939
Score = 30.4 bits (67), Expect = 4.7
Identities = 14/57 (24%), Positives = 30/57 (52%)
Query: 123 ESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQ 179
E +++ +EE K +EEL++ + + ELEE + + + LQ +Q ++ +
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAE 906
>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
Length = 1498
Score = 60.1 bits (144), Expect = 6e-09
Identities = 32/152 (21%), Positives = 76/152 (50%)
Query: 35 KNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQL 94
K +++ + E+ ++ + ++ L++E+ ++ ++ LQ + +++ + ++ EQ Q
Sbjct: 789 KEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQ 848
Query: 95 EEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESV 154
+ ++ R+ + QLIS LKA +S++ +EL + E + E + L V
Sbjct: 849 KVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREV 908
Query: 155 ESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
+ + L+ HLQ +Q+E M+ L ++
Sbjct: 909 AQVRQHMADLEGHLQSAQKERDEMETHLQSLQ 940
Score = 58.9 bits (141), Expect = 1e-08
Identities = 40/174 (22%), Positives = 85/174 (48%), Gaps = 4/174 (2%)
Query: 14 TIPAVADVLKYSCIVCWS-SREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQK 72
++ + D LK SC W R +++ L+ K ++ +++Q +++ QR ++
Sbjct: 465 SLSSEVDTLKQSC---WDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVED 521
Query: 73 LQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEE 132
+Q + +L +Q L+ QL++V+ + + + +AE++S +S Y+++
Sbjct: 522 MQRSMLSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEISSLQSVRQWYQQQ 581
Query: 133 LAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
LA A+E RLQ E A ++ + LE L+ Q+++ Q + M+ K
Sbjct: 582 LALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLENVSLSQQLTETQHRSMKEK 635
Score = 55.8 bits (133), Expect = 1e-07
Identities = 38/156 (24%), Positives = 77/156 (49%), Gaps = 13/156 (8%)
Query: 33 REKNNVEQDLKEKEDTIKQ-------RTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLD 85
R +E+ +E +T+++ ++ +V+ LQ E +QK++ Q Q + +++
Sbjct: 794 RGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVE 853
Query: 86 ELDE---QKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSR 142
K QL +LK RK+ E + L+ EL + T E EL++ E+++
Sbjct: 854 AYRRDATSKDQLISELKATRKRLDSE---LKELRQELMQVHGEKRTAEAELSRLHREVAQ 910
Query: 143 LQQETAELEESVESGKAQLEPLQQHLQDSQQEISSM 178
++Q A+LE ++S + + + ++ HLQ Q + M
Sbjct: 911 VRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQM 946
Score = 55.8 bits (133), Expect = 1e-07
Identities = 38/135 (28%), Positives = 63/135 (46%), Gaps = 7/135 (5%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQREN-------TNLQKLQAQKQQVQELLDE 86
EK E +L + Q + DL+ +Q T+LQ LQ K+Q+ + +
Sbjct: 893 EKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEA 952
Query: 87 LDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQE 146
+ K Q+EE +E RK E+ Q + L ++LTS + ++ T + A LSR QE
Sbjct: 953 NEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQE 1012
Query: 147 TAELEESVESGKAQL 161
+E+ ++ QL
Sbjct: 1013 ALAAKEAADAELGQL 1027
Score = 54.7 bits (130), Expect = 2e-07
Identities = 47/176 (26%), Positives = 88/176 (50%), Gaps = 28/176 (15%)
Query: 31 SSREKNNVEQDLKEKEDTIKQRTSEVQDLQ-------DEVQRENTNLQKLQAQKQQVQEL 83
+S E + V+++L+ KE +++ +E DLQ E+ + L + +AQ Q +Q+
Sbjct: 1212 ASLELSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQFQAELAEARAQLQLLQKQ 1271
Query: 84 LDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRL 143
LDE ++ ++++ ++ + ++ + I SLK +L E Q R+EL L
Sbjct: 1272 LDEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQQLDLTEQQ----------GRKELEGL 1321
Query: 144 QQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLME----MKDLENHNSQL 195
QQ +++ K++LE Q+ L +Q++ +Q K+ E MK L N QL
Sbjct: 1322 QQ-------LLQNVKSELEMAQEDLSMTQKDKFMLQAKVSELKNNMKTLLQQNQQL 1370
Score = 51.6 bits (122), Expect = 2e-06
Identities = 36/169 (21%), Positives = 74/169 (43%), Gaps = 3/169 (1%)
Query: 19 ADVLKYSCIVCWSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQ 78
AD+L K VE+DL+ + + + +Q + D L++++
Sbjct: 647 ADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLL 706
Query: 79 QVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE 138
Q + L+ L ++ L +QL ++ Q + +L+ ++++ + E A +
Sbjct: 707 QRDQQLEALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASRED 766
Query: 139 ELSRLQQETAELE---ESVESGKAQLEPLQQHLQDSQQEISSMQMKLME 184
+ LQ E LE ++ +SGK +L+ + L++ +E S KL E
Sbjct: 767 TICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLRE 815
Score = 49.7 bits (117), Expect = 7e-06
Identities = 35/155 (22%), Positives = 77/155 (49%), Gaps = 13/155 (8%)
Query: 38 VEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEE- 96
V+ L+ KE+ +Q VQ LQ +++E +K+ + K+QV E + +
Sbjct: 1156 VQAVLQRKEEEDRQMKHLVQALQASLEKEK---EKVNSLKEQVAAAKVEAGHNRRHFKAA 1212
Query: 97 --QLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESV 154
+L EV+K+ + L+ L+AE + + + +E+A+ + EL+ + + L++ +
Sbjct: 1213 SLELSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQFQAELAEARAQLQLLQKQL 1272
Query: 155 ES-------GKAQLEPLQQHLQDSQQEISSMQMKL 182
+ G ++E L+ + ++EI S++ +L
Sbjct: 1273 DEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQQL 1307
Score = 49.3 bits (116), Expect = 1e-05
Identities = 34/151 (22%), Positives = 73/151 (48%)
Query: 37 NVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEE 96
++EQ L++ + T+ QR +++ LQ E L Q Q ++ LD L +L+
Sbjct: 693 SLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQA 752
Query: 97 QLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVES 156
+L E++ + A I L+ E E+ + + + RL++ T E E++E
Sbjct: 753 RLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEK 812
Query: 157 GKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
+ +L ++ QQE ++++ ++ ++K+
Sbjct: 813 LREELAIKSGQVEHLQQETAALKKQMQKIKE 843
Score = 47.0 bits (110), Expect = 5e-05
Identities = 31/150 (20%), Positives = 64/150 (42%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
+EK +E L+ Q E +LQ ++ +T LQ Q+ D L +
Sbjct: 412 KEKMRLEGQLEALSLEASQALKEKAELQAQLAALSTKLQAQVECSHSSQQRQDSLSSEVD 471
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
L++ ++ + + ++ + A L S + + EE+ + ++ +Q+ +
Sbjct: 472 TLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRSMLSKDN 531
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKL 182
+V + Q+ LQ LQ Q E +++ KL
Sbjct: 532 TVHDLRQQMTALQSQLQQVQLERTTLTSKL 561
Score = 45.8 bits (107), Expect = 1e-04
Identities = 57/279 (20%), Positives = 109/279 (39%), Gaps = 29/279 (10%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQE-------LLDE 86
E+ + LK + I S Q Q ++ +LQ + +Q LL+
Sbjct: 553 ERTTLTSKLKASQAEISSLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMTQAGLLEH 612
Query: 87 LDEQKAQLEEQLKEVRKKCAEE----AQLISSLKAELTSQESQISTYEE----------- 131
L + L +QL E + + +E A + ++A++ QE+ +E
Sbjct: 613 LKLENVSLSQQLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQR 672
Query: 132 ---ELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQE-ISSMQMKLMEMKD 187
E RE L R+ A LE+ +E K L Q L+ QQE + M+ + +
Sbjct: 673 RLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEA 732
Query: 188 LENHNSQLNWCSSPHSILVNGATDYCSLSTSSSETANL--NEHVEGQSNLESEPIHQESP 245
L++ L+ + + L + + S +T L NE + ++ L++ +E
Sbjct: 733 LQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEEL 792
Query: 246 ARSSPELLPSGVTDENEVTTAVTEKVCSELDNNRHSKEE 284
R + L G + +E + E++ + H ++E
Sbjct: 793 DRGA-RRLEEGTEETSETLEKLREELAIKSGQVEHLQQE 830
Score = 44.3 bits (103), Expect = 3e-04
Identities = 26/108 (24%), Positives = 54/108 (50%)
Query: 79 QVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE 138
QVQ +L +E+ Q++ ++ ++ +E + ++SLK ++ + + + A
Sbjct: 1155 QVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASL 1214
Query: 139 ELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
ELS +++E E V+ +A+ + LQ QEI+ Q +L E +
Sbjct: 1215 ELSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQFQAELAEAR 1262
Score = 40.4 bits (93), Expect = 0.005
Identities = 33/164 (20%), Positives = 72/164 (43%), Gaps = 11/164 (6%)
Query: 32 SREKNNVEQDLKEKEDTIKQRTSEVQ----DLQDEVQRENTNLQKLQAQKQQVQELLDEL 87
S + L + DT+KQ +++ DLQ+ ++ +N +L Q +E
Sbjct: 456 SHSSQQRQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEE----- 510
Query: 88 DEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQET 147
Q +L +++++++ + + L+ ++T+ +SQ+ + E +L Q E
Sbjct: 511 --QYQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEI 568
Query: 148 AELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENH 191
+ L+ + + QL Q+ Q E++ +Q+ M L H
Sbjct: 569 SSLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMTQAGLLEH 612
Score = 40.4 bits (93), Expect = 0.005
Identities = 32/132 (24%), Positives = 61/132 (46%), Gaps = 10/132 (7%)
Query: 71 QKLQAQKQQVQELLDELDEQKA------QLEEQLKEVRKKCAEEAQLISSLKAELTSQES 124
Q+L+ +++V EL DEL E + +LEE K++ + E ++ L +
Sbjct: 1074 QELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALRE 1133
Query: 125 QISTYEEELAKAREELSRLQQETAEL----EESVESGKAQLEPLQQHLQDSQQEISSMQM 180
S E LAK +L +L + + EE K ++ LQ L+ +++++S++
Sbjct: 1134 HNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKE 1193
Query: 181 KLMEMKDLENHN 192
++ K HN
Sbjct: 1194 QVAAAKVEAGHN 1205
Score = 38.5 bits (88), Expect = 0.017
Identities = 40/217 (18%), Positives = 88/217 (40%), Gaps = 11/217 (5%)
Query: 16 PAVADVLKYSCIVCWSSREKNNVEQDLKEKEDTIKQRTS---EVQDLQDEVQRENTNLQK 72
P++ DVL+ + ++ N E ++ + D+I S + Q+E+ + +
Sbjct: 359 PSIKDVLQAAAAEHQDQGQEVNGE--VRSRRDSICSSVSLESSAAETQEEMLQVLKEKMR 416
Query: 73 LQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEE 132
L+ Q + + + ++KA+L+ QL + K + + S + S S++ T ++
Sbjct: 417 LEGQLEALSLEASQALKEKAELQAQLAALSTKLQAQVECSHSSQQRQDSLSSEVDTLKQS 476
Query: 133 LAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLME----MKDL 188
++ LQ S+ S L+ ++ Q ++ MQ ++ + DL
Sbjct: 477 CWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDL 536
Query: 189 ENHNSQLNWCSSPHSILVNGATDYCSLSTSSSETANL 225
+ L S + + T L S +E ++L
Sbjct: 537 RQQMTALQ--SQLQQVQLERTTLTSKLKASQAEISSL 571
Score = 38.1 bits (87), Expect = 0.022
Identities = 25/140 (17%), Positives = 66/140 (47%)
Query: 36 NNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLE 95
+ ++ L E + R + LQ+E LQ ++ K+++ L+E +
Sbjct: 748 DELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETS 807
Query: 96 EQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVE 155
E L+++R++ A ++ + L+ E + + Q+ +E+ + + + +++ ++ +
Sbjct: 808 ETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLIS 867
Query: 156 SGKAQLEPLQQHLQDSQQEI 175
KA + L L++ +QE+
Sbjct: 868 ELKATRKRLDSELKELRQEL 887
Score = 37.7 bits (86), Expect = 0.029
Identities = 34/148 (22%), Positives = 69/148 (46%), Gaps = 9/148 (6%)
Query: 56 VQDLQDEVQRENTNLQKLQAQKQQVQEL----LDELDEQKAQLEEQLKE---VRKKCAEE 108
+Q L+ E+Q + + L+ + Q+V L L+E E+ +LE++L+E RKK
Sbjct: 1044 IQALEAELQAVSHSKTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRL 1103
Query: 109 AQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHL 168
+ L EL ++ +++ + A RE S L+ A+ E + Q++ + Q
Sbjct: 1104 EESNKKLALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRK 1163
Query: 169 QDSQQEISSMQMKLMEMKDLENHNSQLN 196
++ +++ + L LE ++N
Sbjct: 1164 EEEDRQMKHLVQAL--QASLEKEKEKVN 1189
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 59.3 bits (142), Expect = 9e-09
Identities = 41/169 (24%), Positives = 88/169 (52%), Gaps = 21/169 (12%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQK----LQAQKQQVQE------- 82
EK EQ +KE T+ +E+++LQ ++Q+E LQK L+ K+ Q+
Sbjct: 1106 EKLQKEQKIKEHATTV----NELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNME 1161
Query: 83 ------LLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKA 136
L+ EL+++ +++++ ++ + Q +L+ E+TS +S + YEE+ K
Sbjct: 1162 IADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKI 1221
Query: 137 REELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEM 185
++ L + ++E A+ +++ L+ L+ SQQ++ +++L E+
Sbjct: 1222 KQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEI 1270
Score = 57.4 bits (137), Expect = 4e-08
Identities = 33/143 (23%), Positives = 74/143 (51%), Gaps = 10/143 (6%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E+ +KE + + ++++DL+ E++ + + LQ + +Q + + +E+ ++++ L
Sbjct: 1166 ERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLL 1225
Query: 99 KEVRKKCAEEAQ-------LISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELE 151
+ +K+ A+ Q L +SLK EL + + Q+ Y+ +LA+ E ++ + L+
Sbjct: 1226 VKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHE---HLK 1282
Query: 152 ESVESGKAQLEPLQQHLQDSQQE 174
S E + L QQ + Q+E
Sbjct: 1283 TSAEQHQRTLSAYQQRVTALQEE 1305
Score = 56.6 bits (135), Expect = 6e-08
Identities = 41/163 (25%), Positives = 85/163 (52%), Gaps = 13/163 (7%)
Query: 36 NNVEQDLKEKEDTIKQRTS--EVQDLQDEVQRENTNLQK-LQAQKQQVQELL-------D 85
N+ +DL + +T++ EVQ L EVQR + K L+A+K Q ++ + +
Sbjct: 1065 NSDNEDLLARIETLQSNAKLLEVQIL--EVQRAKAMVDKELEAEKLQKEQKIKEHATTVN 1122
Query: 86 ELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQ 145
EL+E + QL+++ K+++K +E +L+ + T +I+ YE + + ++L+
Sbjct: 1123 ELEELQVQLQKEKKQLQKTM-QELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNN 1181
Query: 146 ETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDL 188
+ +LE+ ++ K + E LQ+ + Q + + K ++K L
Sbjct: 1182 KIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQL 1224
Score = 53.5 bits (127), Expect = 5e-07
Identities = 64/270 (23%), Positives = 127/270 (47%), Gaps = 28/270 (10%)
Query: 18 VADVLKYSCIVCWSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQK 77
V +VLK S E +Q+ + E I Q ++QD Q+ +Q + LQ LQ++
Sbjct: 1327 VHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEH 1386
Query: 78 QQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKA- 136
+ E +++ ++ E +L+E K C+ +++ + +K+E T SQ+++ E L +
Sbjct: 1387 DTLLERHNKMLQETVSKEAELRE--KLCSIQSENM-MMKSEHTQTVSQLTSQNEVLRNSF 1443
Query: 137 REELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEIS--SMQMKLMEMKDLENHNSQ 194
R+++ LQ+E + E+++ +++E L++ S S Q L +++ N +
Sbjct: 1444 RDQVRHLQEEHRKTVETLQQQLSKMEAQLFQLKNEPTTRSPVSSQQSLKNLRERRNTDLP 1503
Query: 195 LNWCSSPHSILVN-----GATDYCSLSTSSSETANLNEHVEG-QSNLESEPIHQE----- 243
L H++ TD S+S++S+ T +L + + ++ LE H E
Sbjct: 1504 L---LDMHTVTREEGEGMETTDTESVSSASTYTQSLEQLLNSPETKLEPPLWHAEFTKEE 1560
Query: 244 ------SPARSSPELLPSGVTDENEVTTAV 267
S +S+ L +G+ E E T A+
Sbjct: 1561 LVQKLSSTTKSADHL--NGLLRETEATNAI 1588
Score = 52.4 bits (124), Expect = 1e-06
Identities = 49/177 (27%), Positives = 82/177 (46%), Gaps = 24/177 (13%)
Query: 33 REKNNVEQDLKEK----EDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD 88
+E VEQ + EK EDT+K+ S+ L+DEV N KL+ Q ++ DE
Sbjct: 321 QENTFVEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIK---DEFF 377
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQIS-TYEEELAKAREELSRLQQET 147
++ LE ++ E+ E+ +I LK+EL Q T E+ + + + Q+E
Sbjct: 378 HEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEI 437
Query: 148 AELEES---------------VESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLE 189
+EL E+ ++ K Q E LQQ Q++ S++ ++ME+ E
Sbjct: 438 SELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLR-EIMEILQTE 493
Score = 43.9 bits (102), Expect = 4e-04
Identities = 43/185 (23%), Positives = 86/185 (46%), Gaps = 27/185 (14%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
+E N++ L++KE ++ R +E+ L+D + A+ V+ D L K
Sbjct: 904 KEHENLKPLLEQKE--LRDRRAELILLKDSL-----------AKSPSVKN--DPLSSVK- 947
Query: 93 QLEEQLKEVRKKCAEEAQLISSL-------KAELTSQESQISTYEEELAKAREELSRLQQ 145
+LEE+++ + K+C E+ + I+ + K EL S + T +EEL R E +L
Sbjct: 948 ELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSA 1007
Query: 146 ETAELEESVESGK---AQLEPLQQHLQDSQQEISSMQMKLMEM-KDLENHNSQLNWCSSP 201
+L + ES K + E + L ++ ++ + ++ ++ + L N Q +S
Sbjct: 1008 SMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSD 1067
Query: 202 HSILV 206
+ L+
Sbjct: 1068 NEDLL 1072
Score = 43.1 bits (100), Expect = 7e-04
Identities = 35/154 (22%), Positives = 81/154 (52%), Gaps = 4/154 (2%)
Query: 38 VEQDLKEKEDTIKQRTSEVQD-LQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEE 96
VEQ ++ + ++Q+ +E+ L++ ++ ++ N QKL+ Q++ L ++ + A+++
Sbjct: 631 VEQTIQYNSE-LEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKS 689
Query: 97 QLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVES 156
+E K +E+ QL L+ L+ +E I +E + + ++L + +E L + +E+
Sbjct: 690 LYEENNKLSSEKKQLSRDLEVFLSQKEDVI--LKEHITQLEKKLQLMVEEQDNLNKLLEN 747
Query: 157 GKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLEN 190
+ Q ++ L +E+ S + E KD+ N
Sbjct: 748 EQVQKLFVKTQLYGFLKEMGSEVSEDSEEKDVVN 781
Score = 42.4 bits (98), Expect = 0.001
Identities = 56/261 (21%), Positives = 113/261 (43%), Gaps = 37/261 (14%)
Query: 42 LKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEV 101
LKE + + SE +D+ + +Q +L K+ +K L + DE+ +LE+++
Sbjct: 763 LKEMGSEVSE-DSEEKDVVNVLQAVGESLAKINEEKCN---LAFQRDEKVLELEKEI--- 815
Query: 102 RKKCAEEAQLI--SSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKA 159
KC +E ++ LK+ L E + +EL + + E LQ + E++ + E +
Sbjct: 816 --KCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRL 873
Query: 160 QLEPLQQHLQDSQQEISSMQM----------------KLMEMKDLENHNSQLNWCSSPHS 203
+ + L +++ Q S ++ L+E K+L + ++L
Sbjct: 874 ENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAEL-------- 925
Query: 204 ILVNGATDYCSLSTSSSETANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDENEV 263
IL+ + S S + +++ E E NLE E +E + +L+ E +
Sbjct: 926 ILLKDSLAK-SPSVKNDPLSSVKELEEKIENLEKECKEKEEKI-NKIKLVAVKAKKELDS 983
Query: 264 TTAVTEKVCSELDNNRHSKEE 284
+ T+ V EL++ R K++
Sbjct: 984 SRKETQTVKEELESLRSEKDQ 1004
Score = 41.6 bits (96), Expect = 0.002
Identities = 35/164 (21%), Positives = 74/164 (45%), Gaps = 18/164 (10%)
Query: 34 EKNNVEQDL-KEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
EK + + D+ KE+ + + R ++DL +++ + + + + + ++ L
Sbjct: 1027 EKQSEQLDVEKERANNFEHR---IEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAK 1083
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
LE Q+ EV++ +A + L+AE +E +I +E + E EL+
Sbjct: 1084 LLEVQILEVQRA---KAMVDKELEAEKLQKEQKI-----------KEHATTVNELEELQV 1129
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLN 196
++ K QL+ Q L+ +++ + ME+ D E +LN
Sbjct: 1130 QLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELN 1173
Score = 39.7 bits (91), Expect = 0.008
Identities = 35/158 (22%), Positives = 71/158 (44%), Gaps = 6/158 (3%)
Query: 43 KEKEDTI---KQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLK 99
+EK+D I K E+ + + +RE + +L + +Q + EL+++ +L L+
Sbjct: 594 EEKDDFINKLKNSHEEMDNFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGLE 653
Query: 100 EVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKA 159
E K+ + Q + L ++ E+ EE ++L E +L +E +
Sbjct: 654 ETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLS 713
Query: 160 QLEP--LQQHLQDSQQEISSMQMKLMEM-KDLENHNSQ 194
Q E L++H+ ++++ M + + K LEN Q
Sbjct: 714 QKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQ 751
Score = 38.5 bits (88), Expect = 0.017
Identities = 30/162 (18%), Positives = 74/162 (45%), Gaps = 10/162 (6%)
Query: 43 KEKEDTIKQRTSEVQDLQDEVQRENTN-------LQKLQAQKQQV---QELLDELDEQKA 92
+E E +Q+ S+V +LQ +++ T + +LQ + +++ QEL+ EL+
Sbjct: 503 QEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQELVPELENTIK 562
Query: 93 QLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEE 152
L+E+ ++ ++ L+ ++ S + + +L + EE+ ++ E
Sbjct: 563 NLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCEREER 622
Query: 153 SVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQ 194
+ ++E Q+ + +Q+++ + L E ++ N Q
Sbjct: 623 LILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQ 664
Score = 37.4 bits (85), Expect = 0.038
Identities = 56/272 (20%), Positives = 112/272 (41%), Gaps = 53/272 (19%)
Query: 42 LKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEE----- 96
L E+ D + +E + +++EN + KQ+V++ + ++ + +LE+
Sbjct: 74 LTERLDALLLEKAETEQQCLSLKKENIKM------KQEVEDSVTKMGDAHKELEQSHINY 127
Query: 97 ---------QLKEVRKKCAEE-AQLISSLKAELTSQ-------------ESQISTYEEEL 133
+L VR K +E+ A L L+ + +Q E + +EE+
Sbjct: 128 VKEIENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEI 187
Query: 134 AKAR----EELSRLQQE----TAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEM 185
K R E++ LQ++ T E +E+V + +E QH Q+ I+S+Q +L+++
Sbjct: 188 EKIRPGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHY---QKNINSLQEELLQL 244
Query: 186 KDLENHN-----SQLNWCSSPHSILVNGATDYCSLSTSSSETANLNEHVEGQSNLESEPI 240
K + Q+ + H +N + E + N ++ + E E +
Sbjct: 245 KAIHQEEVKELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKN--IQKKYECELENL 302
Query: 241 HQESPARSSPELLPSGVTDENE-VTTAVTEKV 271
+ + + + S + EN V V EKV
Sbjct: 303 RKATSNANQDNQICSILLQENTFVEQVVNEKV 334
Score = 35.8 bits (81), Expect = 0.11
Identities = 45/219 (20%), Positives = 88/219 (40%), Gaps = 23/219 (10%)
Query: 29 CWSSREKNNVEQDLKEK---------EDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQ 79
C++ + N Q LKE+ E + E L E+Q + LQ +KQ+
Sbjct: 416 CYTVEQHNREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQE 475
Query: 80 VQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKA-ELTSQESQISTYEEELAKARE 138
+ L E L+ +L E K ++E + + +A ++ + ++ T E E
Sbjct: 476 AILNYESLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLE 535
Query: 139 ELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD--LENHNSQLN 196
++RLQ E +L + +L P ++ + QE + + + + +D L+ ++N
Sbjct: 536 TVNRLQGENEKL-----LSQQELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKIN 590
Query: 197 WCSSPHSILVNGATDYCSLSTSSSETANLNEHVEGQSNL 235
+ +N L S E N ++ E + L
Sbjct: 591 SLTEEKDDFIN------KLKNSHEEMDNFHKKCEREERL 623
Score = 35.4 bits (80), Expect = 0.15
Identities = 46/234 (19%), Positives = 97/234 (41%), Gaps = 22/234 (9%)
Query: 20 DVLKYSCIVCWSSREKNNVEQDLKE-KEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQ 78
+V + C + S++E L E KE+ +KQ + +++Q + + E NL+K +
Sbjct: 251 EVKELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNAN 310
Query: 79 QVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE 138
Q ++ L ++ +E+ + E + L+ L ESQ S ++E+
Sbjct: 311 QDNQICSILLQENTFVEQVVNE----------KVKHLEDTLKELESQHSILKDEVTYMNN 360
Query: 139 ELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQE----ISSMQMKLMEMK-----DLE 189
+L+ + +++ + LE L +++E I ++ +L + +E
Sbjct: 361 LKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVE 420
Query: 190 NHNSQLNWCSSPHSILVNGATDYCSLSTSSSETANLNEHVEGQSNLESEPIHQE 243
HN ++ H ++ + LS S E L ++G + E + QE
Sbjct: 421 QHNREVQSLKEQHQKEISELNE-TFLSDSEKEKLTLMFEIQGLKE-QCENLQQE 472
Score = 32.3 bits (72), Expect = 1.2
Identities = 40/190 (21%), Positives = 78/190 (41%), Gaps = 28/190 (14%)
Query: 35 KNNVEQDLKEKEDTIKQRTSEVQDLQDEVQR---ENTNLQKLQAQKQQVQELLDELDEQK 91
K D+ E + ++ +E L + V R EN L Q +++ + L E+
Sbjct: 509 KQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQELVPELENTIKNLQEKN 568
Query: 92 -------AQLEEQLKEVRKK----CAEEAQLISSLK---AELTSQESQISTYEEELAKAR 137
+Q + LKE+ K E+ I+ LK E+ + + E + +
Sbjct: 569 GVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCEREERLILELG 628
Query: 138 EELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSM--QMKLM---------EMK 186
+++ + Q +ELE+ V LE + + Q++ + QMK++ E+K
Sbjct: 629 KKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVK 688
Query: 187 DLENHNSQLN 196
L N++L+
Sbjct: 689 SLYEENNKLS 698
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 59.3 bits (142), Expect = 9e-09
Identities = 59/283 (20%), Positives = 117/283 (41%), Gaps = 47/283 (16%)
Query: 49 IKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEE 108
+ ++ Q L++E+ T Q L+A+ +Q+Q+ +E ++ QL+ ++ ++ K E
Sbjct: 367 LSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLET 426
Query: 109 AQLISSLKAELTSQ----ESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPL 164
+ + L Q ++ E+++A + +LSRL+++ E + + QL+
Sbjct: 427 ERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKT 486
Query: 165 QQHLQDSQQEISSMQMKLMEMKD---------------LENHNSQLNWCSSPHSILVNGA 209
+Q Q+ Q S KL E ++ ++N + L S+L
Sbjct: 487 KQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKER 546
Query: 210 TD-YCSLSTSSSETANLNE-------------------------HVEGQSNLESEPIHQE 243
D Y + ETA LN+ H + Q NL + Q+
Sbjct: 547 EDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQK 606
Query: 244 SPARSSPELLPSGVTDENEVTTAVTE--KVCSELDNNRHSKEE 284
+ R++ + + S T NE+ + + E + S+LD +K E
Sbjct: 607 AHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTE 649
Score = 56.6 bits (135), Expect = 6e-08
Identities = 60/299 (20%), Positives = 127/299 (42%), Gaps = 47/299 (15%)
Query: 31 SSREKNNVEQDLK---EKEDTIKQRTSE----VQDLQDEVQRENTNLQKLQAQKQQVQEL 83
S +E+ ++LK EK ++Q+ ++ V D E+Q L++ Q + ++++
Sbjct: 98 SLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQM 157
Query: 84 LDELDEQKAQLEEQLKEVRKKCAE---------------------EAQLISSLKAELTSQ 122
D +++ AQL ++ +++ K E EA +I LK EL +
Sbjct: 158 KDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQR 217
Query: 123 ES------------QISTYEEELAKARE-ELSRLQQETAELEESVESGKAQLEPLQQHLQ 169
Q+ T + + RE E +L+ E +L+ S +A + L+ L
Sbjct: 218 PGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELA 277
Query: 170 DSQQEISSMQMKLMEMKDLENHNSQLNWCSSPHSILVNGATDYCSLSTSSSETANLNEHV 229
QE++ +L ++K N +Q N + + L+ DY L +E + +++
Sbjct: 278 KGPQEVAVYVQELQKLKSSVNELTQKNQTLTEN--LLKKEQDYTKLEEKHNEESVSKKNI 335
Query: 230 EG---QSNLESEPIHQE-SPARSSPELLPSGVTDENEVTTAVTEKVCSELDNNRHSKEE 284
+ Q +L+ + + S + +S + ++++ E T + E++ +H K E
Sbjct: 336 QATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAE 394
Score = 55.5 bits (132), Expect = 1e-07
Identities = 36/171 (21%), Positives = 86/171 (50%), Gaps = 12/171 (7%)
Query: 36 NNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLE 95
+ +E LKE ++ + ++L+ ++++ + +++A K+Q + L + + LE
Sbjct: 705 SQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLE 764
Query: 96 EQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREE-------LSRLQQET- 147
+ E+ K+ E +++SS + +L + + + +++L K EE L QET
Sbjct: 765 LRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETK 824
Query: 148 ---AELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD-LENHNSQ 194
EL +++ +L+ ++ + E+S+++ KL ++ D L+N S+
Sbjct: 825 IQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSE 875
Score = 54.3 bits (129), Expect = 3e-07
Identities = 54/219 (24%), Positives = 100/219 (45%), Gaps = 28/219 (12%)
Query: 37 NVEQDLKEKEDTIKQRTSEVQDLQDEVQR---ENTNLQKLQAQKQQVQELLDELDEQKAQ 93
N+E L++ ++ I E +DL ++Q E L +LQ + +QE + +L E+
Sbjct: 527 NLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKN 586
Query: 94 LEEQLKEVRKKCAEEAQ----LISSLKAELTSQESQISTYEEELAKAREELSRLQ---QE 146
E K+ ++ ++ Q + + + + S E+ ++ +L +++E++S+L +
Sbjct: 587 QSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKA 646
Query: 147 TAELEESVESGK-AQLEPLQQH-------LQDSQQEISSMQMKL----MEMKDLENHNSQ 194
EL S E+ K AQ LQ H LQD QQE++ + +L +++D + H
Sbjct: 647 KTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEH--- 703
Query: 195 LNWCSSPHSILVNGATDYCSLSTSSSETANLNEHVEGQS 233
CS S L Y SL + E + +E S
Sbjct: 704 ---CSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADS 739
Score = 54.3 bits (129), Expect = 3e-07
Identities = 35/168 (20%), Positives = 94/168 (55%), Gaps = 12/168 (7%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDEL----D 88
+E+ +++ L+++++ Q E+ +Q+++ + L++ + ++QQ+Q ++EL +
Sbjct: 910 KEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSE 969
Query: 89 EQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETA 148
++K Q+E E++ ++ +L + L+ +LT +ELA +E++S LQ
Sbjct: 970 QKKKQIEALQGELKIAVLQKTELENKLQQQLTQA-------AQELAAEKEKISVLQNNYE 1022
Query: 149 ELEESVESGKAQLEPLQQHLQDSQQEISSMQMKL-MEMKDLENHNSQL 195
+ +E+ + ++ + L ++Q++ S++ KL + +DL ++ +Q+
Sbjct: 1023 KSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQI 1070
Score = 52.8 bits (125), Expect = 9e-07
Identities = 51/204 (25%), Positives = 92/204 (45%), Gaps = 51/204 (25%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELD----- 88
E N++++ L + ++T+KQ E Q LQ + N Q + +K+Q++ L EL
Sbjct: 932 ELNSMQEQLIQAQNTLKQNEKEEQQLQGNI---NELKQSSEQKKKQIEALQGELKIAVLQ 988
Query: 89 --EQKAQLEEQLKEVRKKCAEEAQLISSLK---------------------AELTSQESQ 125
E + +L++QL + ++ A E + IS L+ +EL +
Sbjct: 989 KTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQD 1048
Query: 126 ISTYEEELAKAREEL--------------SRLQQETAELEESVESGKAQLEPLQQHLQDS 171
+ + EE+L+ A+E+L L+ A LE+ + QL+ + LQD
Sbjct: 1049 LKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDI 1108
Query: 172 QQEISSMQMKLMEMKDLENHNSQL 195
Q+E K ++ K+L N S+L
Sbjct: 1109 QKE------KSLKEKELVNEKSKL 1126
Score = 51.6 bits (122), Expect = 2e-06
Identities = 47/216 (21%), Positives = 94/216 (43%), Gaps = 10/216 (4%)
Query: 31 SSREKNNVEQDLKEKE----DTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDE 86
+ R+ LKE+ + + + +V DLQ ++ R L++ ++Q LD+
Sbjct: 426 TERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDK 485
Query: 87 LDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQE 146
+Q + + + K E + + ++ ++ +I E L K++E +S L++E
Sbjct: 486 TKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKE 545
Query: 147 TAELEESVESGK---AQLEPLQQHLQDSQQEISSMQMKLMEMKDLENH-NSQLNWCSSPH 202
+L +++G+ A L LQ+ Q++++ + KL + L+
Sbjct: 546 REDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQ 605
Query: 203 SILVNGATD-YCSLSTSSSE-TANLNEHVEGQSNLE 236
+ A D SL TS +E + LNE E S L+
Sbjct: 606 KAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLD 641
Score = 51.2 bits (121), Expect = 3e-06
Identities = 53/252 (21%), Positives = 119/252 (47%), Gaps = 8/252 (3%)
Query: 35 KNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQL 94
K +EQD +KE +++R +QD+Q E + L +++ +++E+ +++ +L
Sbjct: 1084 KATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKL 1143
Query: 95 EEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESV 154
E+LK + + +E + K L Q+ ++ + L A E+ R QQ L++ V
Sbjct: 1144 NEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQ---ILKDQV 1200
Query: 155 ESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW-CSSPHSILVNGATDYC 213
+ + +L+ ++ ++ + S ++ K + MK E + ++L ++ + L ++
Sbjct: 1201 KKEEEELK--KEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQ 1258
Query: 214 SLSTSSSETANLNEHVEGQ-SNLESEPIHQESPARSSPELLPSGVTDENEVTTAVTEKVC 272
S SE + + G+ + LE+ + + R+ E G + ++ T V E +
Sbjct: 1259 SSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLE-LQ 1317
Query: 273 SELDNNRHSKEE 284
+LDN + +E
Sbjct: 1318 RKLDNTTAAVQE 1329
Score = 50.1 bits (118), Expect = 6e-06
Identities = 39/163 (23%), Positives = 81/163 (49%), Gaps = 21/163 (12%)
Query: 33 REKNNVEQD--------LKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELL 84
+EKN+ Q+ LK + ++ KQ ++L D+VQ + +L+ Q + ++ +
Sbjct: 567 QEKNHTLQEQVTQLTEKLKNQSESHKQAQ---ENLHDQVQEQKAHLRAAQDRVLSLETSV 623
Query: 85 DELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQ 144
+EL+ Q + +E++ ++ + + +L+ S +A T+Q + + + L A+ L Q
Sbjct: 624 NELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNH---LDTAQNALQDKQ 680
Query: 145 QETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
QE ++ QL+ + LQD Q+ S ++ L E K+
Sbjct: 681 QELNKIT-------TQLDQVTAKLQDKQEHCSQLESHLKEYKE 716
Score = 49.7 bits (117), Expect = 7e-06
Identities = 43/172 (25%), Positives = 79/172 (45%), Gaps = 21/172 (12%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQ 93
E ++ E TI Q SE+ EV LQKL++ ++ + L E +
Sbjct: 254 ECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLK 313
Query: 94 LEEQLKEVRKKCAEEAQLISSLKAELTSQE-------SQISTYEEELAKAREELS----- 141
E+ ++ +K EE+ +++A L ++ S++S E L + ELS
Sbjct: 314 KEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEA 373
Query: 142 --RLQQETAELEESVESGKAQLEPLQQHLQDSQQ-------EISSMQMKLME 184
+L++E +E+E + KA+ + LQQ ++ +Q EI+ + KL+E
Sbjct: 374 TQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLE 425
Score = 46.6 bits (109), Expect = 6e-05
Identities = 44/204 (21%), Positives = 94/204 (46%), Gaps = 17/204 (8%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
+Q+L + + Q T+++QD Q+ + ++L++ + + +++ +EL+ Q +LE
Sbjct: 680 QQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADS 739
Query: 99 KEVR-------KKCAEEAQLISSLKAELTSQESQISTYEE-------ELAKAREELSRLQ 144
EV+ + ++ QL + L+ T Q+ +E +L K E L ++
Sbjct: 740 LEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIK 799
Query: 145 QETAELEESVESGKAQLEPLQQHLQDSQQEISS-MQMKLMEMKDLENHNSQLNWCSSPHS 203
Q+ + EE + K E L Q + +E+++ +Q + E++ ++ L S
Sbjct: 800 QKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVK 859
Query: 204 ILVNGATDYCSLSTSSSETANLNE 227
++ +D SL S SE N+
Sbjct: 860 DKLSKVSD--SLKNSKSEFEKENQ 881
Score = 46.6 bits (109), Expect = 6e-05
Identities = 41/158 (25%), Positives = 77/158 (48%), Gaps = 14/158 (8%)
Query: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQK-LQAQKQQVQEL---LDELD 88
+E + + + E T K+ ++Q + +E L+K L+ +K+ +L L+ +
Sbjct: 878 KENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQ 937
Query: 89 EQKAQLEEQLKEVRKKCAEEAQL---ISSLKAELTSQESQISTYEEELAKA---REEL-S 141
EQ Q + LK+ K EE QL I+ LK ++ QI + EL A + EL +
Sbjct: 938 EQLIQAQNTLKQNEK---EEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELEN 994
Query: 142 RLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQ 179
+LQQ+ + + + + K ++ LQ + + SQ+ +Q
Sbjct: 995 KLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQ 1032
Score = 45.1 bits (105), Expect = 2e-04
Identities = 43/175 (24%), Positives = 80/175 (45%), Gaps = 19/175 (10%)
Query: 32 SREK-NNVEQDLKEKEDTIKQ----RTSEVQDLQDE-------VQRENTNLQKLQAQKQQ 79
S+EK + ++ +K K + + +T++ DLQ+ +Q + L K+ Q Q
Sbjct: 633 SKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQ 692
Query: 80 VQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSL-----KAELTSQESQISTYE--EE 132
V L + E +QLE LKE ++K Q L K E S E + S + ++
Sbjct: 693 VTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQD 752
Query: 133 LAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 187
L + R+ + L+ EL + +E K + + LQ + + S++ KL + ++
Sbjct: 753 LQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEE 807
Score = 44.7 bits (104), Expect = 2e-04
Identities = 37/136 (27%), Positives = 64/136 (47%), Gaps = 22/136 (16%)
Query: 110 QLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQ 169
Q + L+A L ++ Y EEL K E+ LQQ+ A+ + V A+L+ L+Q L+
Sbjct: 90 QEVQDLQASLKEEK----WYSEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLE 145
Query: 170 DSQQEISSMQMKLMEMKDL-ENHNSQLNWCSSPHSILVNGATDYCSLSTSSSETANLNEH 228
++Q E + +MKDL E +QL AT+ + + E +L E
Sbjct: 146 EAQTE----NFNIKQMKDLFEQKAAQL-------------ATEIADIKSKYDEERSLREA 188
Query: 229 VEGQSNLESEPIHQES 244
E + +E +++E+
Sbjct: 189 AEQKVTRLTEELNKEA 204
Score = 44.7 bits (104), Expect = 2e-04
Identities = 44/221 (19%), Positives = 98/221 (44%), Gaps = 14/221 (6%)
Query: 58 DLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKA 117
DLQ + + + QKL Q+++ Q L + + + + Q +E+ + + +K
Sbjct: 787 DLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKM 846
Query: 118 ELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEIS- 176
E + +++ST +++L+K + L+ +E E+ + GKA + L++ ++ + ++
Sbjct: 847 EKEALMTELSTVKDKLSKVSDS---LKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQV 903
Query: 177 SMQMKLMEMKDLENHNSQLNWCSSPHSILVNGATDYCSLSTSSSETANLNEHVEGQSNLE 236
M+ L E K+L+ + S + +N + + ++ N E + Q N+
Sbjct: 904 QMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQL-IQAQNTLKQNEKEEQQLQGNIN 962
Query: 237 SEPIHQESPARSSPELLPSGVTDENEVTTAVTEKVCSELDN 277
E + L + E+ AV +K +EL+N
Sbjct: 963 ELKQSSEQKKKQIEAL-------QGELKIAVLQK--TELEN 994
Score = 44.7 bits (104), Expect = 2e-04
Identities = 33/161 (20%), Positives = 79/161 (49%), Gaps = 18/161 (11%)
Query: 40 QDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQK-----------QQVQE---LLD 85
QDLK E+ + ++ ++++ +N +Q+L+ K QQ+QE L
Sbjct: 1047 QDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQ 1106
Query: 86 ELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYE----EELAKAREELS 141
++ ++K+ E++L + K AE ++ + E+T ++ +++ +E+ ++
Sbjct: 1107 DIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQ 1166
Query: 142 RLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKL 182
L Q+ EL+ +S KA +E +++ Q + ++ + +L
Sbjct: 1167 LLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEEL 1207
Score = 43.1 bits (100), Expect = 7e-04
Identities = 28/160 (17%), Positives = 76/160 (47%), Gaps = 8/160 (5%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
+Q KE+E+ K+ + L E++ + ++K + + ++ + L+E ++++
Sbjct: 1198 DQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEW 1257
Query: 99 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEE-------LAKAREELSRLQQETAELE 151
+ +++ +E + L+ E+ E+ + ++E K E+ +LQ + EL+
Sbjct: 1258 QSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQ 1317
Query: 152 ESVESGKAQLEPLQQHLQDSQ-QEISSMQMKLMEMKDLEN 190
+++ A ++ L + Q Q + ++ K E +++N
Sbjct: 1318 RKLDNTTAAVQELGRENQSLQIKHTQALNRKWAEDNEVQN 1357
Score = 38.9 bits (89), Expect = 0.013
Identities = 39/163 (23%), Positives = 71/163 (43%), Gaps = 30/163 (18%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQK--------LQAQKQQV----Q 81
E + V+ L + D++K SE + + + +L+K LQ Q + +
Sbjct: 854 ELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQK 913
Query: 82 ELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELS 141
EL L+++K + Q LK EL S + Q+ + L + +E
Sbjct: 914 ELKKSLEKEK-EASHQ-----------------LKLELNSMQEQLIQAQNTLKQNEKEEQ 955
Query: 142 RLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLME 184
+LQ EL++S E K Q+E LQ L+ + + + ++ KL +
Sbjct: 956 QLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQ 998
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 59.3 bits (142), Expect = 9e-09
Identities = 49/155 (31%), Positives = 75/155 (48%), Gaps = 12/155 (7%)
Query: 40 QDLKEKEDTIKQRT--SEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQ 97
Q ++ E KQR SE+ +E QRE +KLQ +K LL E K QLEE+
Sbjct: 1449 QQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDM---LLAEAFSLKQQLEEK 1505
Query: 98 LKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESG 157
++ A Q + SL+AEL SQ S E LAK +++L L+ + + EE ++
Sbjct: 1506 DMDI----AGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQ 1561
Query: 158 KAQLEPLQQ---HLQDSQQEISSMQMKLMEMKDLE 189
++ L+Q L+ + + K ME +D E
Sbjct: 1562 AGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEE 1596
Score = 49.7 bits (117), Expect = 7e-06
Identities = 37/164 (22%), Positives = 82/164 (50%), Gaps = 18/164 (10%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E+ ++E + T K+ E +D + EV+++N K+Q++ L +L + + L
Sbjct: 1376 ERAVREVDFTKKRLQQEFED-KLEVEQQN---------KRQLERRLGDLQADSEESQRAL 1425
Query: 99 KEVRKKCAEEAQLISSLKAELTSQ-------ESQISTYEEELAKAREELSRLQQETAELE 151
++++KKC + K L Q E + ++ EL++A EE R + + +L+
Sbjct: 1426 QQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQ 1485
Query: 152 ESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK-DLENHNSQ 194
+ A+ L+Q L++ +I+ K++ ++ +L++ +SQ
Sbjct: 1486 REKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQ 1529
Score = 48.1 bits (113), Expect = 2e-05
Identities = 42/170 (24%), Positives = 79/170 (46%), Gaps = 12/170 (7%)
Query: 22 LKYSCIVCWSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQK-LQAQKQQV 80
LKY V K ++Q+ ++K + +Q +++ ++Q ++ Q+ LQ K++
Sbjct: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
Query: 81 QELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREEL 140
Q L EL + K LE Q +VR E+ Q +S++S EE + + +
Sbjct: 1433 QRLTAELQDTKLHLEGQ--QVRNHELEKKQ---------RRFDSELSQAHEEAQREKLQR 1481
Query: 141 SRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLEN 190
+LQ+E L S K QLE + Q++ S++ +L ++ E+
Sbjct: 1482 EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQES 1531
Score = 45.4 bits (106), Expect = 1e-04
Identities = 32/156 (20%), Positives = 77/156 (49%), Gaps = 8/156 (5%)
Query: 31 SSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQ 90
S RE ++ L+E E T + ++ E++ L Q + + L+EQ
Sbjct: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIE-------DLHLQIDDIAKAKTALEEQ 1733
Query: 91 KAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAEL 150
++L+ + E++ + E+ + ++ L + + +Q S ++ + +L +E EL
Sbjct: 1734 LSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQEL 1793
Query: 151 EESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
+E +++ ++Q+E L+Q + D + +S + K+ E++
Sbjct: 1794 QEKLQALQSQVEFLEQSMVD-KSLVSRQEAKIRELE 1828
Score = 45.1 bits (105), Expect = 2e-04
Identities = 63/271 (23%), Positives = 116/271 (42%), Gaps = 29/271 (10%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQ----RENTNLQKLQAQKQQVQELLDELDE 89
E +++Q L+EK+ I T +V L+ E+Q +E+ + L K+Q+++L ++ +
Sbjct: 1494 EAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKD 1553
Query: 90 QKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQ--ESQISTYEEELAKAREEL-SRLQQE 146
Q+ +L+EQ + + E+A+L ++ E Q ++ + +EE+ +AR+ +L+Q
Sbjct: 1554 QEEELDEQAGTI--QMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQM 1611
Query: 147 TAELEESVES------GKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNWCSS 200
+LEE E K +LE L D Q + + KDL+ + L
Sbjct: 1612 EVQLEEEYEDKQKVLREKRELEGKLATLSD-QVNRRDFESEKRLRKDLKRTKALLADAQL 1670
Query: 201 PHSILVNGATDYCSLSTSSSETANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDE 260
L N A S E A L +E + + E L + D
Sbjct: 1671 MLDHLKNSA-------PSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDI 1723
Query: 261 NEVTTAVTEKVC------SELDNNRHSKEED 285
+ TA+ E++ +E+ N +ED
Sbjct: 1724 AKAKTALEEQLSRLQREKNEIQNRLEEDQED 1754
Score = 43.5 bits (101), Expect = 5e-04
Identities = 42/174 (24%), Positives = 82/174 (47%), Gaps = 14/174 (8%)
Query: 31 SSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQ 90
+ +E+N + + E I + TSE+ D ++ + + L A++ + ++ + EL Q
Sbjct: 1273 AEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQ 1332
Query: 91 KAQLEEQLKEVRKKCAEEAQLI--SSLKAELTSQESQIS---TYEEELAKAREELSRLQQ 145
L++Q+ EV + EA+LI + + E+ ++ YE + + RLQQ
Sbjct: 1333 YDALKKQM-EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQ 1391
Query: 146 ETAELEESVESGKAQLE----PLQQHLQDSQQEISSMQMKLM----EMKDLENH 191
E + E + K QLE LQ ++SQ+ + ++ K E++D + H
Sbjct: 1392 EFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLH 1445
Score = 43.1 bits (100), Expect = 7e-04
Identities = 46/193 (23%), Positives = 92/193 (47%), Gaps = 22/193 (11%)
Query: 23 KYSCIVCWSSREK---NNVEQDLKEKEDTIKQRTSEVQDLQDEVQ-RENTNLQK--LQAQ 76
K+ V +SR+ N+++ L+E ++ ++Q LQ +V+ E + + K + Q
Sbjct: 1761 KHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQ 1820
Query: 77 KQQVQELLDELDEQKAQ------LEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYE 130
+ +++EL L+ ++ Q L +LKE +K EE + AE +E Q +
Sbjct: 1821 EAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD--QRIAAENREKE-QNKRLQ 1877
Query: 131 EELAKAREELSRLQQETAE-------LEESVESGKAQLEPLQQHLQDSQQEISSMQMKLM 183
+L +EE+ L ++ AE LE +ES +A + LQ L+ + + I +Q +
Sbjct: 1878 RQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIE 1937
Query: 184 EMKDLENHNSQLN 196
+ + + + +N
Sbjct: 1938 DEMESDENEDLIN 1950
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/228 (22%), Positives = 98/228 (42%), Gaps = 24/228 (10%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E ++E E ++ ++V+ L+ R N++KL ++ Q + EQ +L+ QL
Sbjct: 1821 EAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQL 1880
Query: 99 K-------EVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELE 151
+ E+ +K AE ++ L+ +L S E+ + + +L A + + LQ A +E
Sbjct: 1881 RDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQ---AAIE 1937
Query: 152 ESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNWCSSPHSILVNGATD 211
+ +ES D +++ + + +LE+ + S + A+D
Sbjct: 1938 DEMES-------------DENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAASD 1984
Query: 212 YCSLSTSSSETANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTD 259
SL SSS T+ +S+ E +P+ S R S L T+
Sbjct: 1985 DGSLK-SSSPTSYWKSLAPDRSDDEHDPLDNTSRPRYSHSYLSDSDTE 2031
Score = 37.4 bits (85), Expect = 0.038
Identities = 24/106 (22%), Positives = 56/106 (52%), Gaps = 3/106 (2%)
Query: 70 LQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQL---ISSLKAELTSQESQI 126
L ++Q ++Q++ +E+ + +++LE+ KE + +L IS L +ELT + +
Sbjct: 1246 LIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTG 1305
Query: 127 STYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQ 172
+ + L E R ++E EL+ ++ K Q+E ++ + +++
Sbjct: 1306 ESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEAR 1351
Score = 37.0 bits (84), Expect = 0.050
Identities = 16/95 (16%), Positives = 50/95 (52%)
Query: 55 EVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISS 114
++++ +E+Q+ + L+K + ++ +++ D L+ + ++L +L + R +QL+ +
Sbjct: 1255 QIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDA 1314
Query: 115 LKAELTSQESQISTYEEELAKAREELSRLQQETAE 149
AE E ++ + + ++++ ++ E E
Sbjct: 1315 ETAERLRAEKEMKELQTQYDALKKQMEVMEMEVME 1349
Score = 33.5 bits (75), Expect = 0.55
Identities = 20/101 (19%), Positives = 53/101 (52%), Gaps = 7/101 (6%)
Query: 55 EVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISS 114
EVQ +++++ ++ +Q+L+++ ++ ++ +EL +LE ++ E+ + +E S
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGES 1307
Query: 115 LKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVE 155
L ++ + E +A +E+ LQ + L++ +E
Sbjct: 1308 ASQLLDAETA-------ERLRAEKEMKELQTQYDALKKQME 1341
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 59.3 bits (142), Expect = 9e-09
Identities = 49/155 (31%), Positives = 75/155 (48%), Gaps = 12/155 (7%)
Query: 40 QDLKEKEDTIKQRT--SEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQ 97
Q ++ E KQR SE+ +E QRE +KLQ +K LL E K QLEE+
Sbjct: 1449 QQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDM---LLAEAFSLKQQLEEK 1505
Query: 98 LKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESG 157
++ A Q + SL+AEL SQ S E LAK +++L L+ + + EE ++
Sbjct: 1506 DMDI----AGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQ 1561
Query: 158 KAQLEPLQQ---HLQDSQQEISSMQMKLMEMKDLE 189
++ L+Q L+ + + K ME +D E
Sbjct: 1562 AGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEE 1596
Score = 49.7 bits (117), Expect = 7e-06
Identities = 37/164 (22%), Positives = 82/164 (50%), Gaps = 18/164 (10%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E+ ++E + T K+ E +D + EV+++N K+Q++ L +L + + L
Sbjct: 1376 ERAVREVDFTKKRLQQEFED-KLEVEQQN---------KRQLERRLGDLQADSEESQRAL 1425
Query: 99 KEVRKKCAEEAQLISSLKAELTSQ-------ESQISTYEEELAKAREELSRLQQETAELE 151
++++KKC + K L Q E + ++ EL++A EE R + + +L+
Sbjct: 1426 QQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQ 1485
Query: 152 ESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK-DLENHNSQ 194
+ A+ L+Q L++ +I+ K++ ++ +L++ +SQ
Sbjct: 1486 REKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQ 1529
Score = 48.1 bits (113), Expect = 2e-05
Identities = 42/170 (24%), Positives = 79/170 (46%), Gaps = 12/170 (7%)
Query: 22 LKYSCIVCWSSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQK-LQAQKQQV 80
LKY V K ++Q+ ++K + +Q +++ ++Q ++ Q+ LQ K++
Sbjct: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
Query: 81 QELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREEL 140
Q L EL + K LE Q +VR E+ Q +S++S EE + + +
Sbjct: 1433 QRLTAELQDTKLHLEGQ--QVRNHELEKKQ---------RRFDSELSQAHEEAQREKLQR 1481
Query: 141 SRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLEN 190
+LQ+E L S K QLE + Q++ S++ +L ++ E+
Sbjct: 1482 EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQES 1531
Score = 48.1 bits (113), Expect = 2e-05
Identities = 57/233 (24%), Positives = 104/233 (44%), Gaps = 19/233 (8%)
Query: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
E ++E E ++ ++V+ L+ R N++KL ++ Q + EQ +L+ QL
Sbjct: 1821 EAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQL 1880
Query: 99 K-------EVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELE 151
+ E+ +K AE ++ L+ +L S E+ + + +L A + + LQ A +E
Sbjct: 1881 RDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQ---AAIE 1937
Query: 152 ESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENH-----NSQLNWCSSPHSILV 206
+ +ES + E L LQD + + KL D+++ + +W S +
Sbjct: 1938 DEMESD--ENEDLINSLQDMVTKYQKRKNKLEGDSDVDSELEDRVDGVKSWLSK-NKGPS 1994
Query: 207 NGATDYCSLSTSSSETANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTD 259
A+D SL SSS T+ +S+ E +P+ S R S L T+
Sbjct: 1995 KAASDDGSLK-SSSPTSYWKSLAPDRSDDEHDPLDNTSRPRYSHSYLSDSDTE 2046
Score = 45.8 bits (107), Expect = 1e-04
Identities = 63/288 (21%), Positives = 124/288 (43%), Gaps = 42/288 (14%)
Query: 23 KYSCIVCWSSREK---NNVEQDLKEKEDTIKQRTSEVQDLQDEVQ-RENTNLQK--LQAQ 76
K+ V +SR+ N+++ L+E ++ ++Q LQ +V+ E + + K + Q
Sbjct: 1761 KHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQ 1820
Query: 77 KQQVQELLDELDEQKAQ------LEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYE 130
+ +++EL L+ ++ Q L +LKE +K EE + AE +E Q +
Sbjct: 1821 EAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD--QRIAAENREKE-QNKRLQ 1877
Query: 131 EELAKAREELSRLQQETAE-------LEESVESGKAQLEPLQQHLQDSQQEISSMQMKLM 183
+L +EE+ L ++ AE LE +ES +A + LQ L+ + + I +Q +
Sbjct: 1878 RQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIE 1937
Query: 184 EMKDLENHNSQLNWCSSPHSILVNGATDYCSLSTSSSETANLNEHVEGQSNLESEPIHQE 243
+ + + + +N SL ++ +EG S+++SE +
Sbjct: 1938 DEMESDENEDLIN-----------------SLQDMVTKYQKRKNKLEGDSDVDSELEDRV 1980
Query: 244 SPARS--SPELLPS-GVTDENEVTTAVTEKVCSELDNNRHSKEEDPFN 288
+S S PS +D+ + ++ L +R E DP +
Sbjct: 1981 DGVKSWLSKNKGPSKAASDDGSLKSSSPTSYWKSLAPDRSDDEHDPLD 2028
Score = 45.4 bits (106), Expect = 1e-04
Identities = 32/156 (20%), Positives = 77/156 (49%), Gaps = 8/156 (5%)
Query: 31 SSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQ 90
S RE ++ L+E E T + ++ E++ L Q + + L+EQ
Sbjct: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIE-------DLHLQIDDIAKAKTALEEQ 1733
Query: 91 KAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAEL 150
++L+ + E++ + E+ + ++ L + + +Q S ++ + +L +E EL
Sbjct: 1734 LSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQEL 1793
Query: 151 EESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 186
+E +++ ++Q+E L+Q + D + +S + K+ E++
Sbjct: 1794 QEKLQALQSQVEFLEQSMVD-KSLVSRQEAKIRELE 1828
Score = 45.1 bits (105), Expect = 2e-04
Identities = 63/271 (23%), Positives = 116/271 (42%), Gaps = 29/271 (10%)
Query: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQ----RENTNLQKLQAQKQQVQELLDELDE 89
E +++Q L+EK+ I T +V L+ E+Q +E+ + L K+Q+++L ++ +
Sbjct: 1494 EAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKD 1553
Query: 90 QKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQ--ESQISTYEEELAKAREEL-SRLQQE 146
Q+ +L+EQ + + E+A+L ++ E Q ++ + +EE+ +AR+ +L+Q
Sbjct: 1554 QEEELDEQAGTI--QMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQM 1611
Query: 147 TAELEESVES------GKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNWCSS 200
+LEE E K +LE L D Q + + KDL+ + L
Sbjct: 1612 EVQLEEEYEDKQKVLREKRELEGKLATLSD-QVNRRDFESEKRLRKDLKRTKALLADAQL 1670
Query: 201 PHSILVNGATDYCSLSTSSSETANLNEHVEGQSNLESEPIHQESPARSSPELLPSGVTDE 260
L N A S E A L +E + + E L + D
Sbjct: 1671 MLDHLKNSA-------PSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDI 1723
Query: 261 NEVTTAVTEKVC------SELDNNRHSKEED 285
+ TA+ E++ +E+ N +ED
Sbjct: 1724 AKAKTALEEQLSRLQREKNEIQNRLEEDQED 1754
Score = 43.5 bits (101), Expect = 5e-04
Identities = 42/174 (24%), Positives = 82/174 (47%), Gaps = 14/174 (8%)
Query: 31 SSREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQ 90
+ +E+N + + E I + TSE+ D ++ + + L A++ + ++ + EL Q
Sbjct: 1273 AEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQ 1332
Query: 91 KAQLEEQLKEVRKKCAEEAQLI--SSLKAELTSQESQIS---TYEEELAKAREELSRLQQ 145
L++Q+ EV + EA+LI + + E+ ++ YE + + RLQQ
Sbjct: 1333 YDALKKQM-EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQ 1391
Query: 146 ETAELEESVESGKAQLE----PLQQHLQDSQQEISSMQMKLM----EMKDLENH 191
E + E + K QLE LQ ++SQ+ + ++ K E++D + H
Sbjct: 1392 EFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLH 1445
Score = 37.4 bits (85), Expect = 0.038
Identities = 24/106 (22%), Positives = 56/106 (52%), Gaps = 3/106 (2%)
Query: 70 LQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQL---ISSLKAELTSQESQI 126
L ++Q ++Q++ +E+ + +++LE+ KE + +L IS L +ELT + +
Sbjct: 1246 LIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTG 1305
Query: 127 STYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQ 172
+ + L E R ++E EL+ ++ K Q+E ++ + +++
Sbjct: 1306 ESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEAR 1351
Score = 37.0 bits (84), Expect = 0.050
Identities = 16/95 (16%), Positives = 50/95 (52%)
Query: 55 EVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISS 114
++++ +E+Q+ + L+K + ++ +++ D L+ + ++L +L + R +QL+ +
Sbjct: 1255 QIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDA 1314
Query: 115 LKAELTSQESQISTYEEELAKAREELSRLQQETAE 149
AE E ++ + + ++++ ++ E E
Sbjct: 1315 ETAERLRAEKEMKELQTQYDALKKQMEVMEMEVME 1349
Score = 33.5 bits (75), Expect = 0.55
Identities = 20/101 (19%), Positives = 53/101 (52%), Gaps = 7/101 (6%)
Query: 55 EVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISS 114
EVQ +++++ ++ +Q+L+++ ++ ++ +EL +LE ++ E+ + +E S
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGES 1307
Query: 115 LKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVE 155
L ++ + E +A +E+ LQ + L++ +E
Sbjct: 1308 ASQLLDAETA-------ERLRAEKEMKELQTQYDALKKQME 1341
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.124 0.347
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,734,377
Number of Sequences: 37866
Number of extensions: 1271851
Number of successful extensions: 24021
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 870
Number of HSP's successfully gapped in prelim test: 1059
Number of HSP's that attempted gapping in prelim test: 8067
Number of HSP's gapped (non-prelim): 9893
length of query: 582
length of database: 18,247,518
effective HSP length: 108
effective length of query: 474
effective length of database: 14,157,990
effective search space: 6710887260
effective search space used: 6710887260
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.