Guide to the Human Genome
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Search of human proteins with 227497884

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|227497884 brain-enriched guanylate kinase-associated protein
[Homo sapiens]
         (593 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|227497884 brain-enriched guanylate kinase-associated protein ...  1193   0.0  
gi|13124765 brain-enriched guanylate kinase-associated protein [...  1193   0.0  
gi|225690497 tight junction associated protein 1 isoform b [Homo...   172   6e-43
gi|225690495 tight junction associated protein 1 isoform b [Homo...   172   6e-43
gi|225690493 tight junction associated protein 1 isoform b [Homo...   172   6e-43
gi|225690491 tight junction associated protein 1 isoform b [Homo...   172   6e-43
gi|225690489 tight junction associated protein 1 isoform a [Homo...   166   6e-41
gi|225690487 tight junction associated protein 1 isoform a [Homo...   166   6e-41
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    50   4e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    50   4e-06
gi|31982906 cingulin-like 1 [Homo sapiens]                             46   8e-05
gi|62414289 vimentin [Homo sapiens]                                    44   3e-04
gi|60218910 golgi autoantigen, golgin subfamily a, 8G [Homo sapi...    44   3e-04
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]         44   5e-04
gi|46249351 homer 2 isoform 2 [Homo sapiens]                           43   7e-04
gi|46249349 homer 2 isoform 1 [Homo sapiens]                           43   7e-04
gi|110349797 homer 2 isoform 4 [Homo sapiens]                          43   7e-04
gi|110349794 homer 2 isoform 3 [Homo sapiens]                          43   7e-04
gi|109255239 centrosomal protein 63 isoform b [Homo sapiens]           43   0.001
gi|22095367 centrosomal protein 63 isoform a [Homo sapiens]            43   0.001
gi|109255236 centrosomal protein 63 isoform d [Homo sapiens]           43   0.001
gi|7705415 hook homolog 1 [Homo sapiens]                               43   0.001
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    42   0.001
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap...    42   0.002
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap...    42   0.002
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap...    42   0.002
gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens]            42   0.002
gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens]            42   0.002
gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens]            42   0.002
gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens]            42   0.002

>gi|227497884 brain-enriched guanylate kinase-associated protein
           [Homo sapiens]
          Length = 593

 Score = 1193 bits (3086), Expect = 0.0
 Identities = 593/593 (100%), Positives = 593/593 (100%)

Query: 1   MEKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRI 60
           MEKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRI
Sbjct: 1   MEKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRI 60

Query: 61  QSNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDNELY 120
           QSNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDNELY
Sbjct: 61  QSNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDNELY 120

Query: 121 RKDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEKHGCSLPSPLCHPAYADSVPT 180
           RKDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEKHGCSLPSPLCHPAYADSVPT
Sbjct: 121 RKDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEKHGCSLPSPLCHPAYADSVPT 180

Query: 181 CVIAKVLEKPDPASLSSRLSDASARDLAFCDGVEKPGPRPPYKGDIYCSDTALYCPEERR 240
           CVIAKVLEKPDPASLSSRLSDASARDLAFCDGVEKPGPRPPYKGDIYCSDTALYCPEERR
Sbjct: 181 CVIAKVLEKPDPASLSSRLSDASARDLAFCDGVEKPGPRPPYKGDIYCSDTALYCPEERR 240

Query: 241 RDRRPSVDAPVTDVGFLRAQNSTDSAAEEEEEAEAAAFPAGFQHEAFPSYAGSLPTSSSY 300
           RDRRPSVDAPVTDVGFLRAQNSTDSAAEEEEEAEAAAFPAGFQHEAFPSYAGSLPTSSSY
Sbjct: 241 RDRRPSVDAPVTDVGFLRAQNSTDSAAEEEEEAEAAAFPAGFQHEAFPSYAGSLPTSSSY 300

Query: 301 SSFSATSEEKEHAQASTLTASQQAIYLNSRDELFDRKPPATTYEGSPRFAKATAAVAAPL 360
           SSFSATSEEKEHAQASTLTASQQAIYLNSRDELFDRKPPATTYEGSPRFAKATAAVAAPL
Sbjct: 301 SSFSATSEEKEHAQASTLTASQQAIYLNSRDELFDRKPPATTYEGSPRFAKATAAVAAPL 360

Query: 361 EAEVAPGFGRTMSPYPAETFRFPASPGPQQALMPPNLWSLRAKPGTARLPGEDMRGQWRP 420
           EAEVAPGFGRTMSPYPAETFRFPASPGPQQALMPPNLWSLRAKPGTARLPGEDMRGQWRP
Sbjct: 361 EAEVAPGFGRTMSPYPAETFRFPASPGPQQALMPPNLWSLRAKPGTARLPGEDMRGQWRP 420

Query: 421 LSVEDIGAYSYPVSAAGRASPCSFSERYYGGAGGSPGKKADGRASPLYASYKADSFSEGD 480
           LSVEDIGAYSYPVSAAGRASPCSFSERYYGGAGGSPGKKADGRASPLYASYKADSFSEGD
Sbjct: 421 LSVEDIGAYSYPVSAAGRASPCSFSERYYGGAGGSPGKKADGRASPLYASYKADSFSEGD 480

Query: 481 DLSQGHLAEPCFLRAGGDLSLSPGRSADPLPGYAPSEGGDGDRLGVQLCGTASSPEPEQG 540
           DLSQGHLAEPCFLRAGGDLSLSPGRSADPLPGYAPSEGGDGDRLGVQLCGTASSPEPEQG
Sbjct: 481 DLSQGHLAEPCFLRAGGDLSLSPGRSADPLPGYAPSEGGDGDRLGVQLCGTASSPEPEQG 540

Query: 541 SRDSLEPSSMEASPEMHPAARLSPQQAFPRTGGSGLSRKDSLTKAQLYGTLLN 593
           SRDSLEPSSMEASPEMHPAARLSPQQAFPRTGGSGLSRKDSLTKAQLYGTLLN
Sbjct: 541 SRDSLEPSSMEASPEMHPAARLSPQQAFPRTGGSGLSRKDSLTKAQLYGTLLN 593


>gi|13124765 brain-enriched guanylate kinase-associated protein
           [Homo sapiens]
          Length = 593

 Score = 1193 bits (3086), Expect = 0.0
 Identities = 593/593 (100%), Positives = 593/593 (100%)

Query: 1   MEKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRI 60
           MEKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRI
Sbjct: 1   MEKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRI 60

Query: 61  QSNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDNELY 120
           QSNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDNELY
Sbjct: 61  QSNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDNELY 120

Query: 121 RKDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEKHGCSLPSPLCHPAYADSVPT 180
           RKDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEKHGCSLPSPLCHPAYADSVPT
Sbjct: 121 RKDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEKHGCSLPSPLCHPAYADSVPT 180

Query: 181 CVIAKVLEKPDPASLSSRLSDASARDLAFCDGVEKPGPRPPYKGDIYCSDTALYCPEERR 240
           CVIAKVLEKPDPASLSSRLSDASARDLAFCDGVEKPGPRPPYKGDIYCSDTALYCPEERR
Sbjct: 181 CVIAKVLEKPDPASLSSRLSDASARDLAFCDGVEKPGPRPPYKGDIYCSDTALYCPEERR 240

Query: 241 RDRRPSVDAPVTDVGFLRAQNSTDSAAEEEEEAEAAAFPAGFQHEAFPSYAGSLPTSSSY 300
           RDRRPSVDAPVTDVGFLRAQNSTDSAAEEEEEAEAAAFPAGFQHEAFPSYAGSLPTSSSY
Sbjct: 241 RDRRPSVDAPVTDVGFLRAQNSTDSAAEEEEEAEAAAFPAGFQHEAFPSYAGSLPTSSSY 300

Query: 301 SSFSATSEEKEHAQASTLTASQQAIYLNSRDELFDRKPPATTYEGSPRFAKATAAVAAPL 360
           SSFSATSEEKEHAQASTLTASQQAIYLNSRDELFDRKPPATTYEGSPRFAKATAAVAAPL
Sbjct: 301 SSFSATSEEKEHAQASTLTASQQAIYLNSRDELFDRKPPATTYEGSPRFAKATAAVAAPL 360

Query: 361 EAEVAPGFGRTMSPYPAETFRFPASPGPQQALMPPNLWSLRAKPGTARLPGEDMRGQWRP 420
           EAEVAPGFGRTMSPYPAETFRFPASPGPQQALMPPNLWSLRAKPGTARLPGEDMRGQWRP
Sbjct: 361 EAEVAPGFGRTMSPYPAETFRFPASPGPQQALMPPNLWSLRAKPGTARLPGEDMRGQWRP 420

Query: 421 LSVEDIGAYSYPVSAAGRASPCSFSERYYGGAGGSPGKKADGRASPLYASYKADSFSEGD 480
           LSVEDIGAYSYPVSAAGRASPCSFSERYYGGAGGSPGKKADGRASPLYASYKADSFSEGD
Sbjct: 421 LSVEDIGAYSYPVSAAGRASPCSFSERYYGGAGGSPGKKADGRASPLYASYKADSFSEGD 480

Query: 481 DLSQGHLAEPCFLRAGGDLSLSPGRSADPLPGYAPSEGGDGDRLGVQLCGTASSPEPEQG 540
           DLSQGHLAEPCFLRAGGDLSLSPGRSADPLPGYAPSEGGDGDRLGVQLCGTASSPEPEQG
Sbjct: 481 DLSQGHLAEPCFLRAGGDLSLSPGRSADPLPGYAPSEGGDGDRLGVQLCGTASSPEPEQG 540

Query: 541 SRDSLEPSSMEASPEMHPAARLSPQQAFPRTGGSGLSRKDSLTKAQLYGTLLN 593
           SRDSLEPSSMEASPEMHPAARLSPQQAFPRTGGSGLSRKDSLTKAQLYGTLLN
Sbjct: 541 SRDSLEPSSMEASPEMHPAARLSPQQAFPRTGGSGLSRKDSLTKAQLYGTLLN 593


>gi|225690497 tight junction associated protein 1 isoform b [Homo
           sapiens]
          Length = 547

 Score =  172 bits (437), Expect = 6e-43
 Identities = 106/254 (41%), Positives = 151/254 (59%), Gaps = 17/254 (6%)

Query: 2   EKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQ 61
           E++  LQE+  ELR+RL+  T + E LE E +  +  LE+EL +++EEL+K  +K RR+Q
Sbjct: 40  ERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQ 99

Query: 62  SNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDNELYR 121
           ++Y A QR NQELEDKL+ + +  E +++ L  EIV L + LL+AK TI+KL E NE YR
Sbjct: 100 NSYTASQRTNQELEDKLHTLIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYR 159

Query: 122 KDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEK-HGCSLPSPLCHPAYADSVPT 180
            DCNLA QLL+C++++ R HK ++LP + Q+ V  H+      + P P    A    VPT
Sbjct: 160 LDCNLAVQLLKCNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPT 219

Query: 181 CVIAKVLEKPDPASLSSRLSDASARDLA--------FCDGV-------EKPG-PRPPYKG 224
            VIA+VLEKP+   L+S  S ++ R LA          +GV         PG P P   G
Sbjct: 220 SVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNG 279

Query: 225 DIYCSDTALYCPEE 238
           + +   TA   PEE
Sbjct: 280 ECHSLGTARGSPEE 293


>gi|225690495 tight junction associated protein 1 isoform b [Homo
           sapiens]
          Length = 547

 Score =  172 bits (437), Expect = 6e-43
 Identities = 106/254 (41%), Positives = 151/254 (59%), Gaps = 17/254 (6%)

Query: 2   EKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQ 61
           E++  LQE+  ELR+RL+  T + E LE E +  +  LE+EL +++EEL+K  +K RR+Q
Sbjct: 40  ERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQ 99

Query: 62  SNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDNELYR 121
           ++Y A QR NQELEDKL+ + +  E +++ L  EIV L + LL+AK TI+KL E NE YR
Sbjct: 100 NSYTASQRTNQELEDKLHTLIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYR 159

Query: 122 KDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEK-HGCSLPSPLCHPAYADSVPT 180
            DCNLA QLL+C++++ R HK ++LP + Q+ V  H+      + P P    A    VPT
Sbjct: 160 LDCNLAVQLLKCNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPT 219

Query: 181 CVIAKVLEKPDPASLSSRLSDASARDLA--------FCDGV-------EKPG-PRPPYKG 224
            VIA+VLEKP+   L+S  S ++ R LA          +GV         PG P P   G
Sbjct: 220 SVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNG 279

Query: 225 DIYCSDTALYCPEE 238
           + +   TA   PEE
Sbjct: 280 ECHSLGTARGSPEE 293


>gi|225690493 tight junction associated protein 1 isoform b [Homo
           sapiens]
          Length = 547

 Score =  172 bits (437), Expect = 6e-43
 Identities = 106/254 (41%), Positives = 151/254 (59%), Gaps = 17/254 (6%)

Query: 2   EKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQ 61
           E++  LQE+  ELR+RL+  T + E LE E +  +  LE+EL +++EEL+K  +K RR+Q
Sbjct: 40  ERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQ 99

Query: 62  SNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDNELYR 121
           ++Y A QR NQELEDKL+ + +  E +++ L  EIV L + LL+AK TI+KL E NE YR
Sbjct: 100 NSYTASQRTNQELEDKLHTLIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYR 159

Query: 122 KDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEK-HGCSLPSPLCHPAYADSVPT 180
            DCNLA QLL+C++++ R HK ++LP + Q+ V  H+      + P P    A    VPT
Sbjct: 160 LDCNLAVQLLKCNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPT 219

Query: 181 CVIAKVLEKPDPASLSSRLSDASARDLA--------FCDGV-------EKPG-PRPPYKG 224
            VIA+VLEKP+   L+S  S ++ R LA          +GV         PG P P   G
Sbjct: 220 SVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNG 279

Query: 225 DIYCSDTALYCPEE 238
           + +   TA   PEE
Sbjct: 280 ECHSLGTARGSPEE 293


>gi|225690491 tight junction associated protein 1 isoform b [Homo
           sapiens]
          Length = 547

 Score =  172 bits (437), Expect = 6e-43
 Identities = 106/254 (41%), Positives = 151/254 (59%), Gaps = 17/254 (6%)

Query: 2   EKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQ 61
           E++  LQE+  ELR+RL+  T + E LE E +  +  LE+EL +++EEL+K  +K RR+Q
Sbjct: 40  ERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQ 99

Query: 62  SNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDNELYR 121
           ++Y A QR NQELEDKL+ + +  E +++ L  EIV L + LL+AK TI+KL E NE YR
Sbjct: 100 NSYTASQRTNQELEDKLHTLIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYR 159

Query: 122 KDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEK-HGCSLPSPLCHPAYADSVPT 180
            DCNLA QLL+C++++ R HK ++LP + Q+ V  H+      + P P    A    VPT
Sbjct: 160 LDCNLAVQLLKCNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPT 219

Query: 181 CVIAKVLEKPDPASLSSRLSDASARDLA--------FCDGV-------EKPG-PRPPYKG 224
            VIA+VLEKP+   L+S  S ++ R LA          +GV         PG P P   G
Sbjct: 220 SVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNG 279

Query: 225 DIYCSDTALYCPEE 238
           + +   TA   PEE
Sbjct: 280 ECHSLGTARGSPEE 293


>gi|225690489 tight junction associated protein 1 isoform a [Homo
           sapiens]
          Length = 557

 Score =  166 bits (420), Expect = 6e-41
 Identities = 106/264 (40%), Positives = 151/264 (57%), Gaps = 27/264 (10%)

Query: 2   EKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQ 61
           E++  LQE+  ELR+RL+  T + E LE E +  +  LE+EL +++EEL+K  +K RR+Q
Sbjct: 40  ERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQ 99

Query: 62  SNYMALQRINQELEDKLYRMG----------QHYEEEKRALSHEIVALNSHLLEAKVTID 111
           ++Y A QR NQELEDKL+ +           +  E +++ L  EIV L + LL+AK TI+
Sbjct: 100 NSYTASQRTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTIN 159

Query: 112 KLSEDNELYRKDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEK-HGCSLPSPLC 170
           KL E NE YR DCNLA QLL+C++++ R HK ++LP + Q+ V  H+      + P P  
Sbjct: 160 KLEELNERYRLDCNLAVQLLKCNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAP 219

Query: 171 HPAYADSVPTCVIAKVLEKPDPASLSSRLSDASARDLA--------FCDGV-------EK 215
             A    VPT VIA+VLEKP+   L+S  S ++ R LA          +GV         
Sbjct: 220 SLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPA 279

Query: 216 PG-PRPPYKGDIYCSDTALYCPEE 238
           PG P P   G+ +   TA   PEE
Sbjct: 280 PGSPTPQPNGECHSLGTARGSPEE 303


>gi|225690487 tight junction associated protein 1 isoform a [Homo
           sapiens]
          Length = 557

 Score =  166 bits (420), Expect = 6e-41
 Identities = 106/264 (40%), Positives = 151/264 (57%), Gaps = 27/264 (10%)

Query: 2   EKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQ 61
           E++  LQE+  ELR+RL+  T + E LE E +  +  LE+EL +++EEL+K  +K RR+Q
Sbjct: 40  ERMKLLQEENEELRRRLASATRRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQ 99

Query: 62  SNYMALQRINQELEDKLYRMG----------QHYEEEKRALSHEIVALNSHLLEAKVTID 111
           ++Y A QR NQELEDKL+ +           +  E +++ L  EIV L + LL+AK TI+
Sbjct: 100 NSYTASQRTNQELEDKLHTLASLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTIN 159

Query: 112 KLSEDNELYRKDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEK-HGCSLPSPLC 170
           KL E NE YR DCNLA QLL+C++++ R HK ++LP + Q+ V  H+      + P P  
Sbjct: 160 KLEELNERYRLDCNLAVQLLKCNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAP 219

Query: 171 HPAYADSVPTCVIAKVLEKPDPASLSSRLSDASARDLA--------FCDGV-------EK 215
             A    VPT VIA+VLEKP+   L+S  S ++ R LA          +GV         
Sbjct: 220 SLAPGAVVPTSVIARVLEKPESLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPA 279

Query: 216 PG-PRPPYKGDIYCSDTALYCPEE 238
           PG P P   G+ +   TA   PEE
Sbjct: 280 PGSPTPQPNGECHSLGTARGSPEE 303


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 65/249 (26%), Positives = 90/249 (36%), Gaps = 34/249 (13%)

Query: 351 KATAAVAAPLEAEVAPGFGRTMSPYPAETFRFPASPGPQQALMPPNLWSLRAKPGTARLP 410
           KA A  AA   A  APG    ++P P      P SP P   + P  L  L A     R P
Sbjct: 7   KAKAGAAARTPAARAPGL---LTPRP------PGSPRPPPPVTPAALRVLGAAGAVGRKP 57

Query: 411 GEDMRGQWRPLSVEDIGAYSYPVSAAGRASPCSFSERYYGGAG--------------GSP 456
             +  G     ++ +    + P  +AG +S    S     G G               SP
Sbjct: 58  LAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP 117

Query: 457 GKKADGRASPLYASYKADSFSEGDDLSQGHLAEP---CFLRAGGDLSLSPGRSADPLPGY 513
           G +A G   P     K    S  + +++G   E      L AG     S      P P  
Sbjct: 118 G-RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176

Query: 514 APSEGGDGDRLGVQLCGTASSPE-PEQGSRDSLEPSSMEASPEMHPAARLSPQQAFPRTG 572
           A      G  +G+     ++ P  P +G R S+  +S  ++ E  PAAR  P      + 
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP------SA 230

Query: 573 GSGLSRKDS 581
           G GL R  S
Sbjct: 231 GGGLQRPAS 239



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 68/272 (25%), Positives = 94/272 (34%), Gaps = 53/272 (19%)

Query: 339 PATTYEGSPRFAKATAAVAAPLEAE--------VAPGFGRTMSPYPAETF---RFPASPG 387
           P  ++ G   F+ + +   +PL            AP      SP  + T    R P +PG
Sbjct: 534 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 593

Query: 388 PQQALMPPNLWSLRAKPGTARLPGEDMRGQWRPLSVEDIGAYSYPVSAAGRASPCSFSER 447
           P  ++  P L +L   PG    P    R     LS  D+  +S   ++        +   
Sbjct: 594 PDTSVSGPRL-TLALAPGP---PPPPSRSPSSTLSGPDLAGHSSSATSTPEELR-GYDSG 648

Query: 448 YYGGAGGSPGKKADGRASPLYASYKADSFSEGDDLSQGHLAEPCFLRAGGDLSL------ 501
             GGA  SP   A+     L A + A ++S G        A P   R      L      
Sbjct: 649 PEGGAAASPPPDAE-----LAACHPA-AWSRGP-------APPLAFRGAPGAPLPWPPAT 695

Query: 502 SPG--------------RSADPLPGY---APSEGGDGDRLGVQLCGTASSPEPEQGSRDS 544
            PG               SA P PG     PS G  G +        ASS  P+Q     
Sbjct: 696 GPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGE 755

Query: 545 LEPSSMEASPEMHPAAR-LSPQQAFPRTGGSG 575
           L   +++AS   H  +R L    A    GGSG
Sbjct: 756 LPLGALQASVVQHLLSRTLLLAAAEGAAGGSG 787


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 65/249 (26%), Positives = 90/249 (36%), Gaps = 34/249 (13%)

Query: 351 KATAAVAAPLEAEVAPGFGRTMSPYPAETFRFPASPGPQQALMPPNLWSLRAKPGTARLP 410
           KA A  AA   A  APG    ++P P      P SP P   + P  L  L A     R P
Sbjct: 7   KAKAGAAARTPAARAPGL---LTPRP------PGSPRPPPPVTPAALRVLGAAGAVGRKP 57

Query: 411 GEDMRGQWRPLSVEDIGAYSYPVSAAGRASPCSFSERYYGGAG--------------GSP 456
             +  G     ++ +    + P  +AG +S    S     G G               SP
Sbjct: 58  LAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP 117

Query: 457 GKKADGRASPLYASYKADSFSEGDDLSQGHLAEP---CFLRAGGDLSLSPGRSADPLPGY 513
           G +A G   P     K    S  + +++G   E      L AG     S      P P  
Sbjct: 118 G-RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176

Query: 514 APSEGGDGDRLGVQLCGTASSPE-PEQGSRDSLEPSSMEASPEMHPAARLSPQQAFPRTG 572
           A      G  +G+     ++ P  P +G R S+  +S  ++ E  PAAR  P      + 
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP------SA 230

Query: 573 GSGLSRKDS 581
           G GL R  S
Sbjct: 231 GGGLQRPAS 239



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 68/272 (25%), Positives = 94/272 (34%), Gaps = 53/272 (19%)

Query: 339  PATTYEGSPRFAKATAAVAAPLEAE--------VAPGFGRTMSPYPAETF---RFPASPG 387
            P  ++ G   F+ + +   +PL            AP      SP  + T    R P +PG
Sbjct: 803  PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 862

Query: 388  PQQALMPPNLWSLRAKPGTARLPGEDMRGQWRPLSVEDIGAYSYPVSAAGRASPCSFSER 447
            P  ++  P L +L   PG    P    R     LS  D+  +S   ++        +   
Sbjct: 863  PDTSVSGPRL-TLALAPGP---PPPPSRSPSSTLSGPDLAGHSSSATSTPEELR-GYDSG 917

Query: 448  YYGGAGGSPGKKADGRASPLYASYKADSFSEGDDLSQGHLAEPCFLRAGGDLSL------ 501
              GGA  SP   A+     L A + A ++S G        A P   R      L      
Sbjct: 918  PEGGAAASPPPDAE-----LAACHPA-AWSRGP-------APPLAFRGAPGAPLPWPPAT 964

Query: 502  SPG--------------RSADPLPGY---APSEGGDGDRLGVQLCGTASSPEPEQGSRDS 544
             PG               SA P PG     PS G  G +        ASS  P+Q     
Sbjct: 965  GPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGE 1024

Query: 545  LEPSSMEASPEMHPAAR-LSPQQAFPRTGGSG 575
            L   +++AS   H  +R L    A    GGSG
Sbjct: 1025 LPLGALQASVVQHLLSRTLLLAAAEGAAGGSG 1056


>gi|31982906 cingulin-like 1 [Homo sapiens]
          Length = 1302

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 32/118 (27%), Positives = 61/118 (51%), Gaps = 8/118 (6%)

Query: 7   LQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQ-------EELEKVTEKLRR 59
           L++ +GE+R+      H   K E E  S R  LE EL  AQ       +E ++++EKL+ 
Sbjct: 866 LKKYEGEIRQLEEALVHA-RKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKE 924

Query: 60  IQSNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDN 117
                  L+R+  E+E++ + +G+  E+ ++ ++  + A  +  LE +  +D+  E N
Sbjct: 925 ESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKN 982



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 32/119 (26%), Positives = 52/119 (43%), Gaps = 4/119 (3%)

Query: 8   QEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQSNYMAL 67
           Q+   E R+R+     +L     E       L+  L  ++ EL K  E+L +++      
Sbjct: 637 QQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQH 696

Query: 68  QRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKL----SEDNELYRK 122
           Q   ++L+D+L  M    +  KR+   E  AL   LL+AK  +  L     E  +L RK
Sbjct: 697 QTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRK 755



 Score = 33.5 bits (75), Expect = 0.57
 Identities = 22/105 (20%), Positives = 47/105 (44%), Gaps = 3/105 (2%)

Query: 11  KGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQSNYMALQ-- 68
           KG L++ +S    +++KL+ ++D+    L   +  A + +E +  +    + +    +  
Sbjct: 764 KGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMR 823

Query: 69  -RINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDK 112
            ++ QE  +KL    +  E     L  +I  L     +AK T+ K
Sbjct: 824 VKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKK 868


>gi|62414289 vimentin [Homo sapiens]
          Length = 466

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 27/92 (29%), Positives = 45/92 (48%), Gaps = 1/92 (1%)

Query: 26  EKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRI-QSNYMALQRINQELEDKLYRMGQH 84
           + + TEF +TR   ++EL+   +      +K+R + Q N + L  + Q       R+G  
Sbjct: 90  DAINTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQGKSRLGDL 149

Query: 85  YEEEKRALSHEIVALNSHLLEAKVTIDKLSED 116
           YEEE R L  ++  L +     +V  D L+ED
Sbjct: 150 YEEEMRELRRQVDQLTNDKARVEVERDNLAED 181



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 7/109 (6%)

Query: 8   QEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQS----- 62
           +E+  ELR+++   T+   ++E E D+    +     + QEE+ +  E    +QS     
Sbjct: 151 EEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFRQDV 210

Query: 63  NYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTID 111
           +  +L R+  +LE K+  + +     K+    EI  L + + E  V ID
Sbjct: 211 DNASLARL--DLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQID 257


>gi|60218910 golgi autoantigen, golgin subfamily a, 8G [Homo
           sapiens]
          Length = 434

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 33/178 (18%), Positives = 80/178 (44%), Gaps = 17/178 (9%)

Query: 2   EKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYL-------------EIELRRAQE 48
           +++  + ++   L+K   +  +++EKLE      +H +             E+EL+  ++
Sbjct: 49  QRMRKMSQEVCSLKKEKKHDKYRVEKLERSLSKLKHQMAEPLPPEPPAVPSEVELQHLRK 108

Query: 49  ELEKVTEKLRRIQSNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKV 108
           ELE+V  +L+        +  +N+  +++L    +  +E++  L  +   L   L E + 
Sbjct: 109 ELERVAGELQAQVEYNQRISLLNEGQKERLREQEERLQEQQERLPEQEERL-QQLAEPQN 167

Query: 109 TIDKLSEDNELYRKDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEKHGCSLP 166
           +  +L+ +N   +    L  Q+ +  +  G+V +   L +  Q++  L  +    +LP
Sbjct: 168 SFKELNNEN---KSVLQLEQQVKELQEKLGKVKETERLEAASQQKQQLTAQLSLMALP 222


>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
          Length = 2115

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 35/152 (23%), Positives = 68/152 (44%), Gaps = 3/152 (1%)

Query: 3   KLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQS 62
           +L  L+++   L    +    ++E LETE       L  E    +EE ++++  +  +QS
Sbjct: 414 QLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQS 473

Query: 63  NYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDNELYRK 122
           +   L +  +ELE      G     +  +L+ E+  LN+ + +    +  L +  +   K
Sbjct: 474 SISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQ--QAKEK 531

Query: 123 DCNLAAQLLQCSQ-TYGRVHKVSELPSDFQER 153
              LA  L Q  Q + G  H+V +L S  +++
Sbjct: 532 QAQLAQTLQQQEQASQGLRHQVEQLSSSLKQK 563



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 45/182 (24%), Positives = 71/182 (39%), Gaps = 30/182 (16%)

Query: 2   EKLSALQEQKGELRKRLSYTTHKLEKLETEFDST-RHYLEIELRRAQEELEKVTEKLRRI 60
           E+   + E K E R  +    HK E+ E E +   R  LE  L++  E  +  TE LRR 
Sbjct: 731 EQQRCISELKAETRSLVEQ--HKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRE 788

Query: 61  QSNYMALQRINQELEDKLYR------------------MGQHYEEEKRALSHEIVALNSH 102
            +  MA Q   +   ++L +                   G  ++E+   L  E       
Sbjct: 789 LAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQE 848

Query: 103 LLEAKVTIDKLS---------EDNELYRKDCNLAAQLLQCSQTYGRVHKVSELPSDFQER 153
           L EAK  +  +          + NEL     NLA  L Q  +   R  K+++  S  QE+
Sbjct: 849 LQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEK 908

Query: 154 VS 155
           ++
Sbjct: 909 MA 910



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 22/111 (19%), Positives = 52/111 (46%)

Query: 13  ELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQSNYMALQRINQ 72
           +L+  +S  +   E+LE    +    L  ++     EL  +   +++       L++  +
Sbjct: 470 DLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAK 529

Query: 73  ELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDNELYRKD 123
           E + +L +  Q  E+  + L H++  L+S L + +  + +++E  E  R+D
Sbjct: 530 EKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQD 580



 Score = 32.7 bits (73), Expect = 0.97
 Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 3/117 (2%)

Query: 8   QEQKGELRKRLSYTTHKLEKLETE-FDSTRHYLEIELRRAQEELEKVTEKLRRIQSNYMA 66
           Q +K EL +++      +E    E  ++     E+EL+   E+ +K TEK  R+      
Sbjct: 642 QREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQ-QKATEK-ERVAQEKDQ 699

Query: 67  LQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDNELYRKD 123
           LQ   Q L++ L       EEEKR  +  +      + E K     L E ++  RK+
Sbjct: 700 LQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKE 756



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 28/121 (23%), Positives = 56/121 (46%), Gaps = 6/121 (4%)

Query: 1   MEKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYL---EIELRRAQEELEKVTEKL 57
           ++    L+E+   L+ +LS     L +L+      +  +    ++L   ++E   +    
Sbjct: 370 LQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANN 429

Query: 58  RRIQSNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALN---SHLLEAKVTIDKLS 114
            ++Q+    L+    + E KL     H+EEEK+ LS  I  L    S+L +AK  +++ S
Sbjct: 430 TQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQAS 489

Query: 115 E 115
           +
Sbjct: 490 Q 490



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 47/202 (23%), Positives = 71/202 (35%), Gaps = 21/202 (10%)

Query: 394  PPNLWSLRAKPGT---ARLPGEDMRGQWRPLSVEDIGAYSYPVSAAGRASPCSFSERYYG 450
            P +  SLRA   T   ARL   D        ++  +  Y     ++ R S    S     
Sbjct: 1842 PASQASLRATSSTQSLARLGSPDYGNS----ALLSLPGYRPTTRSSARRSQAGVS----- 1892

Query: 451  GAGGSPGKKADGRASPLYASYKADSFSEGDDLSQGHLAEPCFLRAGGDLSLSPGRSADPL 510
             +G  PG+ +    +      + D ++   +L Q +   P  L+    L   P  S   +
Sbjct: 1893 -SGAPPGRNSFYMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLGTI 1951

Query: 511  PGYAPSEGGDGDRLG------VQLCGTASSPEPEQGSRDSLEPSSMEASPEMHPAARLSP 564
                   G   + L       +Q+         +Q  R SLEP     +PE   A    P
Sbjct: 1952 TDEEMKTGDPQETLRRASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFP 2011

Query: 565  QQAFPRTGGSGLSRKDSLTKAQ 586
            +   PR    G  RK S T+AQ
Sbjct: 2012 RPMTPRDRHEG--RKQSTTEAQ 2031


>gi|46249351 homer 2 isoform 2 [Homo sapiens]
          Length = 354

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 35/108 (32%), Positives = 50/108 (46%), Gaps = 8/108 (7%)

Query: 8   QEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQSNYMAL 67
           +E+  +L++R+     +L + ETE    R   EI + +   E E V+EKL        A 
Sbjct: 243 KEKNTQLKRRIEELEAELREKETELKDLRKQSEI-IPQLMSECEYVSEKLE-------AA 294

Query: 68  QRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSE 115
           +R NQ LEDK+  +    EE K    H  V L S L      ID L +
Sbjct: 295 ERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHD 342


>gi|46249349 homer 2 isoform 1 [Homo sapiens]
          Length = 343

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 35/108 (32%), Positives = 50/108 (46%), Gaps = 8/108 (7%)

Query: 8   QEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQSNYMAL 67
           +E+  +L++R+     +L + ETE    R   EI + +   E E V+EKL        A 
Sbjct: 232 KEKNTQLKRRIEELEAELREKETELKDLRKQSEI-IPQLMSECEYVSEKLE-------AA 283

Query: 68  QRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSE 115
           +R NQ LEDK+  +    EE K    H  V L S L      ID L +
Sbjct: 284 ERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHD 331


>gi|110349797 homer 2 isoform 4 [Homo sapiens]
          Length = 299

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 35/108 (32%), Positives = 50/108 (46%), Gaps = 8/108 (7%)

Query: 8   QEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQSNYMAL 67
           +E+  +L++R+     +L + ETE    R   EI + +   E E V+EKL        A 
Sbjct: 188 KEKNTQLKRRIEELEAELREKETELKDLRKQSEI-IPQLMSECEYVSEKLE-------AA 239

Query: 68  QRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSE 115
           +R NQ LEDK+  +    EE K    H  V L S L      ID L +
Sbjct: 240 ERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHD 287


>gi|110349794 homer 2 isoform 3 [Homo sapiens]
          Length = 288

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 35/108 (32%), Positives = 50/108 (46%), Gaps = 8/108 (7%)

Query: 8   QEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQSNYMAL 67
           +E+  +L++R+     +L + ETE    R   EI + +   E E V+EKL        A 
Sbjct: 177 KEKNTQLKRRIEELEAELREKETELKDLRKQSEI-IPQLMSECEYVSEKLE-------AA 228

Query: 68  QRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSE 115
           +R NQ LEDK+  +    EE K    H  V L S L      ID L +
Sbjct: 229 ERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHD 276


>gi|109255239 centrosomal protein 63 isoform b [Homo sapiens]
          Length = 541

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 32/120 (26%), Positives = 60/120 (50%), Gaps = 10/120 (8%)

Query: 6   ALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQE-------ELEKVTEKLR 58
           AL EQ   ++ +L     KLE +E    S   +L  +L RA +       E+E++T ++ 
Sbjct: 176 ALAEQSEIIQAQLVNRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVN 235

Query: 59  RIQSNYMALQRINQELEDKLY---RMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSE 115
            +    M + +  Q+ E+KL    ++ +  +EEKR L   + +  + + EA++  +KL E
Sbjct: 236 DLVGTSMTVLQEQQQKEEKLRESEKLLEALQEEKRELKAALQSQENLIHEARIQKEKLQE 295


>gi|22095367 centrosomal protein 63 isoform a [Homo sapiens]
          Length = 703

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 32/120 (26%), Positives = 60/120 (50%), Gaps = 10/120 (8%)

Query: 6   ALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQE-------ELEKVTEKLR 58
           AL EQ   ++ +L     KLE +E    S   +L  +L RA +       E+E++T ++ 
Sbjct: 176 ALAEQSEIIQAQLVNRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVN 235

Query: 59  RIQSNYMALQRINQELEDKLY---RMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSE 115
            +    M + +  Q+ E+KL    ++ +  +EEKR L   + +  + + EA++  +KL E
Sbjct: 236 DLVGTSMTVLQEQQQKEEKLRESEKLLEALQEEKRELKAALQSQENLIHEARIQKEKLQE 295


>gi|109255236 centrosomal protein 63 isoform d [Homo sapiens]
          Length = 475

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 32/120 (26%), Positives = 60/120 (50%), Gaps = 10/120 (8%)

Query: 6   ALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQE-------ELEKVTEKLR 58
           AL EQ   ++ +L     KLE +E    S   +L  +L RA +       E+E++T ++ 
Sbjct: 176 ALAEQSEIIQAQLVNRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVN 235

Query: 59  RIQSNYMALQRINQELEDKLY---RMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSE 115
            +    M + +  Q+ E+KL    ++ +  +EEKR L   + +  + + EA++  +KL E
Sbjct: 236 DLVGTSMTVLQEQQQKEEKLRESEKLLEALQEEKRELKAALQSQENLIHEARIQKEKLQE 295



 Score = 32.7 bits (73), Expect = 0.97
 Identities = 28/124 (22%), Positives = 57/124 (45%), Gaps = 17/124 (13%)

Query: 4   LSALQEQKGELRKRLSYTTHKL-------EKLETEFDSTRHYLEIEL----------RRA 46
           L ALQE+K EL+  L    + +       EKL+ +  +T     +E           ++ 
Sbjct: 262 LEALQEEKRELKAALQSQENLIHEARIQKEKLQEKVKATNTQHAVEAISLESVSATCKQL 321

Query: 47  QEELEKVTEKLRRIQSNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEA 106
            +EL +  E+L+R++++    +   ++L++++ +  Q Y      +  EI  L   L + 
Sbjct: 322 SQELMEKYEELKRMEAHNNEYKAEIKKLKEQILQGEQSYSSALEGMKMEISHLTQELHQR 381

Query: 107 KVTI 110
            +TI
Sbjct: 382 DITI 385


>gi|7705415 hook homolog 1 [Homo sapiens]
          Length = 728

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 4/123 (3%)

Query: 3   KLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQS 62
           +++ LQ++K  L         KL++L+  FD     +  +   AQ +LE++ E+  R+++
Sbjct: 207 QVTTLQDEKNSLVSENEMMNEKLDQLDGSFDDPNTVVAKKYFHAQLQLEQLQEENFRLEA 266

Query: 63  NYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTID---KLSEDNEL 119
                +   +ELE +L    QH  +E  +L+ E  AL   +   + T D   KL    E+
Sbjct: 267 AKDDYRVHCEELEKQLIEF-QHRNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEI 325

Query: 120 YRK 122
           YR+
Sbjct: 326 YRQ 328


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
           sapiens]
          Length = 2363

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 44/169 (26%), Positives = 79/169 (46%), Gaps = 20/169 (11%)

Query: 8   QEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRI---QSNY 64
           ++Q  E+ KRLS++  +L     E  S R    +EL +   +L+ +TEK + +   Q   
Sbjct: 51  EQQYFEIEKRLSHSQERLVNETRECQSLR----LELEKLNNQLKALTEKNKELEIAQDRN 106

Query: 65  MALQ----RINQELEDK---LYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLS-ED 116
           +A+Q    R  +ELE +   L R  +   +E   L+ ++  LN  L E+  T  +L  + 
Sbjct: 107 IAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKL 166

Query: 117 NELYRKDCNLAAQLLQCSQTYGRVHKV-----SELPSDFQERVSLHMEK 160
           +EL   D ++  +  +  Q    +H       +EL +   E ++L  EK
Sbjct: 167 DELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREK 215



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 42/171 (24%), Positives = 83/171 (48%), Gaps = 23/171 (13%)

Query: 2    EKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQ 61
            E+  ++QE + EL++ L+    K + LE++ ++    L+  L   + E   + E+  ++Q
Sbjct: 1468 EQHVSVQEMQ-ELKETLNQAETKSKSLESQVEN----LQKTLSEKETEARNLQEQTVQLQ 1522

Query: 62   SNYMALQRINQELEDKLYR---MGQHYEEEKRALSHEIVALNSHLLEAKVTIDKLSEDN- 117
            S    L R+ Q+L+D+  +   + Q   E++      IVA  S +       D+L+++N 
Sbjct: 1523 SE---LSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENE 1579

Query: 118  ELYRKDCNLAAQLLQC--------SQTYGRVHKVSELPSDFQERVSLHMEK 160
            EL +++  L  Q  +         SQ  GR+ ++     + QER   H+E+
Sbjct: 1580 ELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQER---HLEQ 1627



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 34/134 (25%), Positives = 60/134 (44%), Gaps = 13/134 (9%)

Query: 2   EKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQ 61
           ++L   Q++   ++ + + T  +LE  + +   T   L  EL    E+++++ EKL+   
Sbjct: 97  KELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESN 156

Query: 62  SNYMALQRINQELE----DKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKL---- 113
           +    LQ    EL+       YR  +  E+EK  L  +   LN+   E K   D+L    
Sbjct: 157 TTKGELQLKLDELQASDVSVKYR-EKRLEQEKELLHSQNTWLNT---ELKTKTDELLALG 212

Query: 114 -SEDNELYRKDCNL 126
             + NE+    CNL
Sbjct: 213 REKGNEILELKCNL 226



 Score = 29.6 bits (65), Expect = 8.2
 Identities = 30/140 (21%), Positives = 59/140 (42%), Gaps = 29/140 (20%)

Query: 1    MEKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLR-- 58
            + +L   +EQ  +L++RL  +T  +E+ +    S    L  E +  +E  + +  +L+  
Sbjct: 938  VSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKES 997

Query: 59   -----RIQSNYMALQRINQELEDKLYR----MGQHYEEEKR------------------A 91
                 +++   M +++  QEL+D   R    M Q   E K+                  A
Sbjct: 998  AEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTA 1057

Query: 92   LSHEIVALNSHLLEAKVTID 111
            LS+E  A      +AK+ ++
Sbjct: 1058 LSNEQQARRDCQEQAKIAVE 1077


>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
           sapiens]
          Length = 600

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 1/87 (1%)

Query: 3   KLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQS 62
           +LS L EQ   L K L     + + L+ E    +    + LR   +++E + ++LR +Q 
Sbjct: 428 QLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSL-LRMELQQVEGLKKELRELQD 486

Query: 63  NYMALQRINQELEDKLYRMGQHYEEEK 89
               LQ+I +E E  L  MG H  + K
Sbjct: 487 EKAELQKICEEQEQALQEMGLHLSQSK 513


>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
           sapiens]
          Length = 600

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 1/87 (1%)

Query: 3   KLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQS 62
           +LS L EQ   L K L     + + L+ E    +    + LR   +++E + ++LR +Q 
Sbjct: 428 QLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSL-LRMELQQVEGLKKELRELQD 486

Query: 63  NYMALQRINQELEDKLYRMGQHYEEEK 89
               LQ+I +E E  L  MG H  + K
Sbjct: 487 EKAELQKICEEQEQALQEMGLHLSQSK 513


>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
           sapiens]
          Length = 708

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 1/87 (1%)

Query: 3   KLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQS 62
           +LS L EQ   L K L     + + L+ E    +    + LR   +++E + ++LR +Q 
Sbjct: 536 QLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSL-LRMELQQVEGLKKELRELQD 594

Query: 63  NYMALQRINQELEDKLYRMGQHYEEEK 89
               LQ+I +E E  L  MG H  + K
Sbjct: 595 EKAELQKICEEQEQALQEMGLHLSQSK 621


>gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens]
          Length = 761

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 32/126 (25%), Positives = 60/126 (47%), Gaps = 16/126 (12%)

Query: 11  KGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQSNYMALQ-- 68
           KG L+K +     KL       +  R+ + I+L    +  E++TE ++ +Q+   +LQ  
Sbjct: 310 KGALKKLIHAA--KLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSE 367

Query: 69  -----RINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKL-------SED 116
                  NQ+L+ KL  M + Y+E +  L  ++    ++ LE +  + K+       +E+
Sbjct: 368 NTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEE 427

Query: 117 NELYRK 122
            E YRK
Sbjct: 428 LETYRK 433



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 39/132 (29%), Positives = 56/132 (42%), Gaps = 29/132 (21%)

Query: 4   LSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQSN 63
           LS L E+K +L ++ S    + E  E E        E E   AQ  LE   EKL R    
Sbjct: 82  LSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQS-LEATCEKLNRS--- 137

Query: 64  YMALQRINQELEDKLYRMGQHYEEEK-----------------RALSHEIVALNSHLLEA 106
                  N ELED++  + +  +EEK                 ++L  E  +L S + EA
Sbjct: 138 -------NSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEA 190

Query: 107 KVTIDKLSEDNE 118
           K+T  K+ + NE
Sbjct: 191 KMTF-KIFQMNE 201



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 65/279 (23%), Positives = 109/279 (39%), Gaps = 56/279 (20%)

Query: 2   EKLSALQEQKGELRKRLSYTTHKLEKLETEFD-STRHYLEIELR-------------RAQ 47
           E +  LQ ++  L+   ++  ++ +KL+ +    T  Y E E++               +
Sbjct: 352 EHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKE 411

Query: 48  EELEKVTEKLRRIQSNYMALQRINQELEDKLYR-----MGQHYEEEKRALSHEIVALNSH 102
           E+L KV EK+          ++  ++LE++L R      GQ    EK+A  + + A N  
Sbjct: 412 EKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARN-- 469

Query: 103 LLEAKVTIDKLSEDNELYRK---DCNLAAQLLQ--------CSQTYGRVHKVSELPSDFQ 151
              A+  ++ L ++N   R+   +  L  +LL+         +  +GR  +    P D Q
Sbjct: 470 ---AERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPNTAFGRGSRGPGNPLDHQ 526

Query: 152 ERVSLHMEKHGCSLPSPLCHPAYADSVPTCVIAKVLEKPDPASLSSRLSDASARDLAFCD 211
                   + G S    L  P  A S             D  SLS    D   R +    
Sbjct: 527 -----ITNERGESSCDRLTDPHRAPS-------------DTGSLSPPW-DQDRRMMFPPP 567

Query: 212 GVEKP-GPRPPYKGDIYCSDTA-LYCPEERRRDRRPSVD 248
           G   P    PP + D +CS++  L  P E R    PS+D
Sbjct: 568 GQSYPDSALPPQRQDRFCSNSGRLSGPAELRSFNMPSLD 606


>gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens]
          Length = 804

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 32/126 (25%), Positives = 60/126 (47%), Gaps = 16/126 (12%)

Query: 11  KGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQSNYMALQ-- 68
           KG L+K +     KL       +  R+ + I+L    +  E++TE ++ +Q+   +LQ  
Sbjct: 310 KGALKKLIHAA--KLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSE 367

Query: 69  -----RINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKL-------SED 116
                  NQ+L+ KL  M + Y+E +  L  ++    ++ LE +  + K+       +E+
Sbjct: 368 NTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEE 427

Query: 117 NELYRK 122
            E YRK
Sbjct: 428 LETYRK 433



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 39/132 (29%), Positives = 56/132 (42%), Gaps = 29/132 (21%)

Query: 4   LSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQSN 63
           LS L E+K +L ++ S    + E  E E        E E   AQ  LE   EKL R    
Sbjct: 82  LSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQS-LEATCEKLNRS--- 137

Query: 64  YMALQRINQELEDKLYRMGQHYEEEK-----------------RALSHEIVALNSHLLEA 106
                  N ELED++  + +  +EEK                 ++L  E  +L S + EA
Sbjct: 138 -------NSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEA 190

Query: 107 KVTIDKLSEDNE 118
           K+T  K+ + NE
Sbjct: 191 KMTF-KIFQMNE 201



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 27/119 (22%), Positives = 53/119 (44%), Gaps = 19/119 (15%)

Query: 2   EKLSALQEQKGELRKRLSYTTHKLEKLETEFD-STRHYLEIELR-------------RAQ 47
           E +  LQ ++  L+   ++  ++ +KL+ +    T  Y E E++               +
Sbjct: 352 EHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKE 411

Query: 48  EELEKVTEKLRRIQSNYMALQRINQELEDKLYR-----MGQHYEEEKRALSHEIVALNS 101
           E+L KV EK+          ++  ++LE++L R      GQ    EK+A  + + A N+
Sbjct: 412 EKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNA 470


>gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens]
          Length = 775

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 32/126 (25%), Positives = 60/126 (47%), Gaps = 16/126 (12%)

Query: 11  KGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQSNYMALQ-- 68
           KG L+K +     KL       +  R+ + I+L    +  E++TE ++ +Q+   +LQ  
Sbjct: 281 KGALKKLIHAA--KLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSE 338

Query: 69  -----RINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKL-------SED 116
                  NQ+L+ KL  M + Y+E +  L  ++    ++ LE +  + K+       +E+
Sbjct: 339 NTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEE 398

Query: 117 NELYRK 122
            E YRK
Sbjct: 399 LETYRK 404



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 39/132 (29%), Positives = 56/132 (42%), Gaps = 29/132 (21%)

Query: 4   LSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQSN 63
           LS L E+K +L ++ S    + E  E E        E E   AQ  LE   EKL R    
Sbjct: 53  LSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQS-LEATCEKLNRS--- 108

Query: 64  YMALQRINQELEDKLYRMGQHYEEEK-----------------RALSHEIVALNSHLLEA 106
                  N ELED++  + +  +EEK                 ++L  E  +L S + EA
Sbjct: 109 -------NSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEA 161

Query: 107 KVTIDKLSEDNE 118
           K+T  K+ + NE
Sbjct: 162 KMTF-KIFQMNE 172



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 27/119 (22%), Positives = 53/119 (44%), Gaps = 19/119 (15%)

Query: 2   EKLSALQEQKGELRKRLSYTTHKLEKLETEFD-STRHYLEIELR-------------RAQ 47
           E +  LQ ++  L+   ++  ++ +KL+ +    T  Y E E++               +
Sbjct: 323 EHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKE 382

Query: 48  EELEKVTEKLRRIQSNYMALQRINQELEDKLYR-----MGQHYEEEKRALSHEIVALNS 101
           E+L KV EK+          ++  ++LE++L R      GQ    EK+A  + + A N+
Sbjct: 383 EKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNA 441


>gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens]
          Length = 792

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 32/126 (25%), Positives = 60/126 (47%), Gaps = 16/126 (12%)

Query: 11  KGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQSNYMALQ-- 68
           KG L+K +     KL       +  R+ + I+L    +  E++TE ++ +Q+   +LQ  
Sbjct: 298 KGALKKLIHAA--KLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSE 355

Query: 69  -----RINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDKL-------SED 116
                  NQ+L+ KL  M + Y+E +  L  ++    ++ LE +  + K+       +E+
Sbjct: 356 NTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEE 415

Query: 117 NELYRK 122
            E YRK
Sbjct: 416 LETYRK 421



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 39/132 (29%), Positives = 56/132 (42%), Gaps = 29/132 (21%)

Query: 4   LSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELEKVTEKLRRIQSN 63
           LS L E+K +L ++ S    + E  E E        E E   AQ  LE   EKL R    
Sbjct: 70  LSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQS-LEATCEKLNRS--- 125

Query: 64  YMALQRINQELEDKLYRMGQHYEEEK-----------------RALSHEIVALNSHLLEA 106
                  N ELED++  + +  +EEK                 ++L  E  +L S + EA
Sbjct: 126 -------NSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEA 178

Query: 107 KVTIDKLSEDNE 118
           K+T  K+ + NE
Sbjct: 179 KMTF-KIFQMNE 189



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 27/119 (22%), Positives = 53/119 (44%), Gaps = 19/119 (15%)

Query: 2   EKLSALQEQKGELRKRLSYTTHKLEKLETEFD-STRHYLEIELR-------------RAQ 47
           E +  LQ ++  L+   ++  ++ +KL+ +    T  Y E E++               +
Sbjct: 340 EHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKE 399

Query: 48  EELEKVTEKLRRIQSNYMALQRINQELEDKLYR-----MGQHYEEEKRALSHEIVALNS 101
           E+L KV EK+          ++  ++LE++L R      GQ    EK+A  + + A N+
Sbjct: 400 EKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNA 458


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,635,457
Number of Sequences: 37866
Number of extensions: 1485741
Number of successful extensions: 8231
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 151
Number of HSP's successfully gapped in prelim test: 563
Number of HSP's that attempted gapping in prelim test: 6382
Number of HSP's gapped (non-prelim): 2234
length of query: 593
length of database: 18,247,518
effective HSP length: 108
effective length of query: 485
effective length of database: 14,157,990
effective search space: 6866625150
effective search space used: 6866625150
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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