BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|22749387 zinc finger, CCHC domain containing 5 [Homo sapiens] (475 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|22749387 zinc finger, CCHC domain containing 5 [Homo sapiens] 982 0.0 gi|94421473 paternally expressed 10 isoform RF1 [Homo sapiens] 122 9e-28 gi|94421475 paternally expressed 10 isoform RF1/2 [Homo sapiens] 120 4e-27 gi|167466262 zinc finger, CCHC domain containing 16 [Homo sapiens] 92 1e-18 gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 79 7e-15 gi|199562283 retrotransposon-like 1 [Homo sapiens] 62 9e-10 gi|6912480 leucine zipper, down-regulated in cancer 1 [Homo sapi... 55 1e-07 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 55 1e-07 gi|110349719 titin isoform N2-A [Homo sapiens] 54 2e-07 gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 53 5e-07 gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens] 52 1e-06 gi|118200335 family with sequence similarity 127, member A [Homo... 51 2e-06 gi|118200337 family with sequence similarity 127, member C [Homo... 51 2e-06 gi|239757911 PREDICTED: similar to Family with sequence similari... 51 3e-06 gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo ... 51 3e-06 gi|118200333 family with sequence similarity 127, member B isofo... 51 3e-06 gi|75677612 leucine rich repeat containing 37, member A3 [Homo s... 50 4e-06 gi|239740955 PREDICTED: similar to c114 SLIT-like testicular pro... 50 6e-06 gi|239740953 PREDICTED: similar to c114 SLIT-like testicular pro... 50 6e-06 gi|116325993 c114 SLIT-like testicular protein [Homo sapiens] 50 6e-06 gi|110665701 leucine rich repeat containing 37A [Homo sapiens] 50 6e-06 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 49 8e-06 gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 48 2e-05 gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H... 48 2e-05 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 48 2e-05 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 48 2e-05 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 48 2e-05 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 48 2e-05 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 48 2e-05 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 48 2e-05 >gi|22749387 zinc finger, CCHC domain containing 5 [Homo sapiens] Length = 475 Score = 982 bits (2538), Expect = 0.0 Identities = 475/475 (100%), Positives = 475/475 (100%) Query: 1 MVEDLAASYIVLKLENEIRQAQVQWLMEENAALQAQIPELQKSQAAKEYDLLRKSSEAKE 60 MVEDLAASYIVLKLENEIRQAQVQWLMEENAALQAQIPELQKSQAAKEYDLLRKSSEAKE Sbjct: 1 MVEDLAASYIVLKLENEIRQAQVQWLMEENAALQAQIPELQKSQAAKEYDLLRKSSEAKE 60 Query: 61 PQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPAT 120 PQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPAT Sbjct: 61 PQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPAT 120 Query: 121 RESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQL 180 RESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQL Sbjct: 121 RESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQL 180 Query: 181 EFLELPPPQEPLEPSNAQEFLELSAAQESLEGLIVVETSAASEFPQAPIGLEATDFPLQY 240 EFLELPPPQEPLEPSNAQEFLELSAAQESLEGLIVVETSAASEFPQAPIGLEATDFPLQY Sbjct: 181 EFLELPPPQEPLEPSNAQEFLELSAAQESLEGLIVVETSAASEFPQAPIGLEATDFPLQY 240 Query: 241 TLTFSGDSQKLPEFLVQLYSYMRVRGHLYPTEAALVSFVGNCFSGRAGWWFQLLLDIQSP 300 TLTFSGDSQKLPEFLVQLYSYMRVRGHLYPTEAALVSFVGNCFSGRAGWWFQLLLDIQSP Sbjct: 241 TLTFSGDSQKLPEFLVQLYSYMRVRGHLYPTEAALVSFVGNCFSGRAGWWFQLLLDIQSP 300 Query: 301 LLEQCESFIPVLQDTFDNPENMKDANQCIHQLCQGEGHVATHFHLIAQELNWDESTLWIQ 360 LLEQCESFIPVLQDTFDNPENMKDANQCIHQLCQGEGHVATHFHLIAQELNWDESTLWIQ Sbjct: 301 LLEQCESFIPVLQDTFDNPENMKDANQCIHQLCQGEGHVATHFHLIAQELNWDESTLWIQ 360 Query: 361 FQEGLASSIQDELSHTSPATNLSDLITQCISLEEKPDPNPLGKSSSAEGDGPESPPAENQ 420 FQEGLASSIQDELSHTSPATNLSDLITQCISLEEKPDPNPLGKSSSAEGDGPESPPAENQ Sbjct: 361 FQEGLASSIQDELSHTSPATNLSDLITQCISLEEKPDPNPLGKSSSAEGDGPESPPAENQ 420 Query: 421 PMQAAINCPHISEAEWVRWHKGRLCLYCGYPGHFARDCPVKPHQALQAGNIQACQ 475 PMQAAINCPHISEAEWVRWHKGRLCLYCGYPGHFARDCPVKPHQALQAGNIQACQ Sbjct: 421 PMQAAINCPHISEAEWVRWHKGRLCLYCGYPGHFARDCPVKPHQALQAGNIQACQ 475 >gi|94421473 paternally expressed 10 isoform RF1 [Homo sapiens] Length = 325 Score = 122 bits (305), Expect = 9e-28 Identities = 89/282 (31%), Positives = 133/282 (47%), Gaps = 39/282 (13%) Query: 214 IVVETSAASEFPQAPIGLEATDFPLQYTLTFSGDSQKLPEFLVQLYSYMRVRGHLYPTEA 273 I + +AA+ P PI E P F G+ L F+ Q +M + + Sbjct: 59 IELRGAAAAAAPPPPIEEEC---PEDLPEKFDGNPDMLAPFMAQCQIFMEKSTRDFSVDR 115 Query: 274 ALVSFVGNCFSGRAGWWFQLLLDIQSPLLEQCESFIPVLQDTFDNPENMKDANQCIHQLC 333 V FV + +GRA W L+ L+ +F+ ++ F++P+ + A + I +L Sbjct: 116 VRVCFVTSMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREVAKRKIRRLR 175 Query: 334 QGEGHVATH---FHLIAQELNWDESTLWIQFQEGLASSIQDELSHTSPATNLSDLITQCI 390 QG G V + F +IAQ+L+W+E L Q+ EGL+ IQ+ELSH A +LS LI QCI Sbjct: 176 QGMGSVIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELSHLEVAKSLSALIGQCI 235 Query: 391 SLEEKPDPNPLGKSSSAEGDGPESPPAENQPMQAAINCPHI------------------- 431 +E + L ++++A P SPP A+ PHI Sbjct: 236 HIERR-----LARAAAAR--KPRSPP-------RALVLPHIASHHQVDPTEPVGGARMRL 281 Query: 432 SEAEWVRWHKGRLCLYCGYPGHFARDCPVKPHQALQAGNIQA 473 ++ E R K LCLYCG GH+A +CP K ++ AGN A Sbjct: 282 TQEEKERRRKLNLCLYCGTGGHYADNCPAKASKSSPAGNSPA 323 >gi|94421475 paternally expressed 10 isoform RF1/2 [Homo sapiens] Length = 708 Score = 120 bits (300), Expect = 4e-27 Identities = 87/280 (31%), Positives = 132/280 (47%), Gaps = 39/280 (13%) Query: 214 IVVETSAASEFPQAPIGLEATDFPLQYTLTFSGDSQKLPEFLVQLYSYMRVRGHLYPTEA 273 I + +AA+ P PI E P F G+ L F+ Q +M + + Sbjct: 59 IELRGAAAAAAPPPPIEEEC---PEDLPEKFDGNPDMLAPFMAQCQIFMEKSTRDFSVDR 115 Query: 274 ALVSFVGNCFSGRAGWWFQLLLDIQSPLLEQCESFIPVLQDTFDNPENMKDANQCIHQLC 333 V FV + +GRA W L+ L+ +F+ ++ F++P+ + A + I +L Sbjct: 116 VRVCFVTSMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREVAKRKIRRLR 175 Query: 334 QGEGHVATH---FHLIAQELNWDESTLWIQFQEGLASSIQDELSHTSPATNLSDLITQCI 390 QG G V + F +IAQ+L+W+E L Q+ EGL+ IQ+ELSH A +LS LI QCI Sbjct: 176 QGMGSVIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELSHLEVAKSLSALIGQCI 235 Query: 391 SLEEKPDPNPLGKSSSAEGDGPESPPAENQPMQAAINCPHI------------------- 431 +E + L ++++A P SPP A+ PHI Sbjct: 236 HIERR-----LARAAAAR--KPRSPP-------RALVLPHIASHHQVDPTEPVGGARMRL 281 Query: 432 SEAEWVRWHKGRLCLYCGYPGHFARDCPVKPHQALQAGNI 471 ++ E R K LCLYCG GH+A +CP K ++ AG + Sbjct: 282 TQEEKERRRKLNLCLYCGTGGHYADNCPAKASKSSPAGKL 321 >gi|167466262 zinc finger, CCHC domain containing 16 [Homo sapiens] Length = 310 Score = 92.0 bits (227), Expect = 1e-18 Identities = 78/264 (29%), Positives = 111/264 (42%), Gaps = 19/264 (7%) Query: 231 LEATDFPLQYTLT----FSGDSQKLPEFLVQLYSYMRVRGHLYPTEAALVSFVGNCFSGR 286 L T P+ Y+L F GD EFL Q+ +Y+ P A + + S + Sbjct: 47 LATTVMPVPYSLEHLTQFHGDPANCSEFLTQVTTYLTALQISNPANDAQIKLFFDYLSQQ 106 Query: 287 AGWWFQLLLDIQSPLLEQCESFIPVLQDTFDNPENMKDANQCIHQLCQGEGHVATH---F 343 + +S LL+Q E+ I Q +F P + + +G+ F Sbjct: 107 LESCGIISGPDKSTLLKQYENLILEFQQSFGKPTKQEINPLMNAKFDKGDNSSQQDPATF 166 Query: 344 HLIAQELNWDESTLWIQFQEGLASSIQDELSHTSPATNLSDLITQCISLEEKPDPNPLGK 403 HL+AQ L +E+ QF++ LA QDE S T NL DLITQCI L++K P Sbjct: 167 HLLAQNLICNETNQSGQFEKALADPNQDEESVTDMMDNLPDLITQCIQLDKKHSDRPELL 226 Query: 404 SSSAEGD------------GPESPPAENQPMQAAINCPHISEAEWVRWHKGRLCLYCGYP 451 S + P PP + P+Q ++ A+ R + +LCLYC Sbjct: 227 QSETQLPLLASLIQHQALFSPTDPPPKKGPIQLREGQLPLTPAKRARQQETQLCLYCSQS 286 Query: 452 GHFARDCPVKPHQALQAGNIQACQ 475 GHF RDC K +A N A Q Sbjct: 287 GHFTRDCLAKRSRAPATTNNTAHQ 310 >gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] Length = 569 Score = 79.3 bits (194), Expect = 7e-15 Identities = 54/164 (32%), Positives = 83/164 (50%), Gaps = 6/164 (3%) Query: 244 FSGDSQKLPEFLVQLYSYMRVRGHLYPTEAALVSFVGNCFSGRAGWWFQLLLDIQSPLLE 303 FSGD L EFL+QL +++ +P A V+F+ + F+G A W + SPL Sbjct: 156 FSGDPVYLAEFLMQLETFIADHEVHFPGGAERVAFLISFFTGEAKDWAISVTQEGSPLHA 215 Query: 304 QCESFIPVLQDTFDNPENMKDANQCIHQLCQGE---GHVATHFHLIAQELNWDESTLWIQ 360 F+ ++ F P + A + I +L QG G A F +AQ L+WD+ L Q Sbjct: 216 NFPRFLDEIRKEFCGPIPPRVAKKAIRKLKQGHCTLGSYADAFQFLAQFLSWDDCRLQNQ 275 Query: 361 FQEGLASSIQDELSHTSPATNLSDLITQCISLEEK---PDPNPL 401 F +GL+ + EL ++ +L +LI +C+ +E K P P PL Sbjct: 276 FLKGLSEFFRKELLWSTEMADLDELILECVEIERKVRVPKPIPL 319 >gi|199562283 retrotransposon-like 1 [Homo sapiens] Length = 1358 Score = 62.4 bits (150), Expect = 9e-10 Identities = 78/336 (23%), Positives = 132/336 (39%), Gaps = 33/336 (9%) Query: 71 PAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPP--M 128 PA+ AQ+ E P P + + LP + +++E + P +E + PP + Sbjct: 47 PASGPAQEKKE--PPSGPLQEMEELPTD--LLQDMEEPSSGPR-------KEIEDPPNDL 95 Query: 129 AHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEA-PEYQETAAQLEFLELPP 187 ++ G A + A + +P + QEA + +E+ + E P Sbjct: 96 LQDLEESCNGSHQARGDPLSGASDRMKEASVNPSGAREEQEAHTDLKESGRE----ETPQ 151 Query: 188 PQEPLEPSNAQEFLELSAAQESLEGLIVVETSAASEFPQAPI----GLEATDFPLQYTLT 243 Q E S A EL A S+ L + A G+ A P Sbjct: 152 EQNQTEHSTA----ELMAMVRSIISLYFRMQDLKEQQRVAEEILIKGINAGQLPAPKH-- 205 Query: 244 FSGDSQKLPEFLVQLYSYMRVRGHLYPTEAALVSFVGNCFSGRAGWWFQLLLDIQSPLLE 303 FSGD ++ EF+V ++ ++ + V +V N SG A W + LL SPL+ Sbjct: 206 FSGDRREFHEFIVLCQLTLQSYPRMFYNDRLRVGYVINHLSGLALEWAKALLQENSPLIG 265 Query: 304 QCESFIPVLQDTFDNPENMKDANQCIHQLCQGEGHVAT----HFHLIAQELNWDESTLWI 359 +F+ + + F+ + ++ A + + + QG G AT F + L W + L Sbjct: 266 DFPAFLEAMSEVFEYRQALRVAEEAMFTIRQG-GRSATEYIDEFQSLVPILGWPDEVLQA 324 Query: 360 QFQEGLASSIQDELSHTSPATNLSDLITQCISLEEK 395 +GL I+ L +L LI + +EEK Sbjct: 325 HLCQGLNEEIRHYLFRVPQPDSLDSLIVLILQIEEK 360 >gi|6912480 leucine zipper, down-regulated in cancer 1 [Homo sapiens] Length = 146 Score = 55.5 bits (132), Expect = 1e-07 Identities = 29/93 (31%), Positives = 53/93 (56%), Gaps = 2/93 (2%) Query: 237 PLQYTLTFSGDSQKLPEFLVQLYSYMRVRGHLYPTEAALVSFVGNCFSGRAGWWFQLLLD 296 P+ + TF+G+S +LPEF+VQ SYM V + + +A V+F+ + +G A W ++ Sbjct: 50 PVPFPETFNGESSRLPEFIVQTASYMLVNENRFCNDAMKVAFLISLLTGEAEEWVVPYIE 109 Query: 297 IQSPLLEQCESFIPVLQDTF--DNPENMKDANQ 327 + SP+L +F+ ++ F D+ E+ D + Sbjct: 110 MDSPILGDYRAFLDEMKQCFGWDDDEDDDDEEE 142 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 55.1 bits (131), Expect = 1e-07 Identities = 49/168 (29%), Positives = 72/168 (42%), Gaps = 14/168 (8%) Query: 28 EENAALQAQIPELQKSQAAKEYDLLRKS-SEAKEPQKLPEHMNPPAAWEAQKTPEFKEPQ 86 EE + + PE KS +E K+ S KE K PE E K E K P Sbjct: 772 EEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEK-------EIPKKEEVKSPV 824 Query: 87 KPPE-PQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTVLEGQGPANTQ 145 K E PQ++ EPP E ++APA P++ +++ + P P V E + PA + Sbjct: 825 KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884 Query: 146 DATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLE 193 E K E +D + P+ +E A++E E P+E E Sbjct: 885 PKESKVEAKKEEAEDKKKVPTPE-----KEAPAKVEVKEDAKPKEKTE 927 Score = 49.3 bits (116), Expect = 8e-06 Identities = 53/217 (24%), Positives = 89/217 (41%), Gaps = 16/217 (7%) Query: 29 ENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPEHMNPPAAWEAQKTPEFKEPQKP 88 E + ++ E ++ +A +E + E +E + E P A EA +PE KE + P Sbjct: 462 EETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAA-SPE-KEAKSP 519 Query: 89 PEPQDLLPWEPPAAWELQEAPA-----APESLAPPATRESQKPPMAHEIPTVLEGQGPAN 143 + + P E + E +EA + +PE PA E++ PP A P E + PA Sbjct: 520 VKEEAKSPAEAKSP-EKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKS-PEKEEAKSPAE 577 Query: 144 TQDATIAQEPKNSEPQDPPNIEKPQEA--PEYQETAAQLEFL-----ELPPPQEPLEPSN 196 + A+ P E + P + P++A P +E + E E P E P Sbjct: 578 VKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK 637 Query: 197 AQEFLELSAAQESLEGLIVVETSAASEFPQAPIGLEA 233 A+ + A E + + E ++P+ EA Sbjct: 638 AKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA 674 Score = 48.5 bits (114), Expect = 1e-05 Identities = 47/181 (25%), Positives = 69/181 (38%), Gaps = 19/181 (10%) Query: 34 QAQIPELQKSQAAKEYDLLRKS-SEAKEPQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQ 92 +A+ PE KS +E K+ S KE K PE P EA+ + K P+K Sbjct: 701 EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLD 760 Query: 93 DLLPWEPPAAWELQEAPA--APESLAPPATRESQKPPMA------------HEIPTVLEG 138 P A E +PA PE P E + P A EIP E Sbjct: 761 VKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEV 820 Query: 139 QGPA----NTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLEP 194 + P Q+ + + PK +E + P K +E + ++ A + P +E EP Sbjct: 821 KSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEP 880 Query: 195 S 195 + Sbjct: 881 A 881 Score = 43.5 bits (101), Expect = 4e-04 Identities = 44/182 (24%), Positives = 82/182 (45%), Gaps = 15/182 (8%) Query: 26 LMEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPEHMNPPAAWEAQKTPEFKEP 85 L E+ A + +IP+ ++ ++ + + + + KEP K E PA KT E K+ Sbjct: 803 LKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPA---TPKTEEKKDS 859 Query: 86 QKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQK-----PPMAHEIPTVLEGQG 140 +K P+ P +P + + A P+ A +E + P E P +E + Sbjct: 860 KKEEAPKKEAP-KPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKE 918 Query: 141 PANTQDAT--IAQEPKNSEPQDPPN-IEKPQEAPEYQETAAQLEFLELPPPQEPLEPSNA 197 A ++ T +EP +++ ++P EK + APE ++T E P ++P + A Sbjct: 919 DAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTK---EEKAKKPEEKPKTEAKA 975 Query: 198 QE 199 +E Sbjct: 976 KE 977 Score = 42.4 bits (98), Expect = 0.001 Identities = 44/190 (23%), Positives = 78/190 (41%), Gaps = 29/190 (15%) Query: 12 LKLENEIRQAQVQWLMEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPEHMNPP 71 +K+++E + V+ +E ++ Q E Q ++ E + EAKE + E Sbjct: 436 IKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTE----EEEKEAKEEEGKEEE---- 487 Query: 72 AAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHE 131 E ++ +E K PPA E A+PE A +E K P + Sbjct: 488 -GGEEEEAEGGEEETK----------SPPA-----EEAASPEKEAKSPVKEEAKSPAEAK 531 Query: 132 IPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQL---EFLELPPP 188 P E + PA + A+ P E + PP + P++ E ++ A++ E + P Sbjct: 532 SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEK--EEAKSPAEVKSPEKAKSPAK 589 Query: 189 QEPLEPSNAQ 198 +E P+ A+ Sbjct: 590 EEAKSPAEAK 599 Score = 41.2 bits (95), Expect = 0.002 Identities = 48/202 (23%), Positives = 76/202 (37%), Gaps = 20/202 (9%) Query: 28 EENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPEHMNPPAAWEAQKTPEFKEPQK 87 E + + + PE KS A +E + +EAK P+K P EA+ E K P K Sbjct: 571 EAKSPAEVKSPEKAKSPAKEE---AKSPAEAKSPEKAKS----PVKEEAKSPAEAKSPVK 623 Query: 88 PPEPQDLLPWEPPAAWE-LQEAPAAPESLAPPATRESQKPPMAHEIPTVLEGQGPANTQD 146 P A +E +PE P E++ P A + P E + P Sbjct: 624 EEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKA-KSPVKAEAKSPEK--- 679 Query: 147 ATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLEPSNAQEFLELSAA 206 A+ P +E + P + P +E A E + P +E P A+ ++ A Sbjct: 680 ---AKSPVKAEAKSPEKAKSP-----VKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK 731 Query: 207 QESLEGLIVVETSAASEFPQAP 228 V E + + E ++P Sbjct: 732 TPEKAKSPVKEEAKSPEKAKSP 753 Score = 36.6 bits (83), Expect = 0.051 Identities = 38/160 (23%), Positives = 68/160 (42%), Gaps = 23/160 (14%) Query: 28 EENAALQAQIPELQKS-----QAAKEYDLLRKSSEAKEPQKLPEHMNPPAAWEAQKTPEF 82 EE +A P++++ + KE + K EA++ +K+P EA E Sbjct: 862 EEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEK-----EAPAKVEV 916 Query: 83 KEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRES--QKPPMAHEIPTVLEGQG 140 KE KP E ++ EP A + + A + A P +++ +K E P + + Sbjct: 917 KEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKP---KTEA 973 Query: 141 PANTQDATIAQEP--------KNSEPQDPPNIEKPQEAPE 172 A D T+++EP + S D + + P++A E Sbjct: 974 KAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATE 1013 Score = 36.2 bits (82), Expect = 0.067 Identities = 42/179 (23%), Positives = 68/179 (37%), Gaps = 22/179 (12%) Query: 34 QAQIPELQKSQAAKEYDLLRKS-----SEAKEPQKLPEHMNPPAAWEAQKTPEFKEPQKP 88 +A+ PE KS E K+ +EAK P+K + A + KE K Sbjct: 659 EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKS 718 Query: 89 PEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAH--EIPTVLEGQGP-ANTQ 145 PE A ++E PE P E++ P A E L+ + P A T Sbjct: 719 PE---------KAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTP 769 Query: 146 DATIAQEPKNSEPQDPPN-----IEKPQEAPEYQETAAQLEFLELPPPQEPLEPSNAQE 199 A+ P + P+ + ++ P++A + A+ E+P +E P +E Sbjct: 770 AKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEE 828 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 54.3 bits (129), Expect = 2e-07 Identities = 46/176 (26%), Positives = 73/176 (41%), Gaps = 23/176 (13%) Query: 37 IPELQKSQAAKEYDLLRKSSEAKEPQKLPEHMNPPAAWEAQKTP-----EFKEPQKPPEP 91 +PE+QK +E + S + P K+PE PA E P E P+ P P Sbjct: 9261 VPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVP 9320 Query: 92 QDLLPWE-------------PPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTVLEG 138 + +P E PP E+ + P E + P ++ + PP ++P V Sbjct: 9321 KKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPA--KVPEV--Q 9376 Query: 139 QGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLEP 194 +G + TI + + S P P I K ++ PE ++ + E PPP+ P P Sbjct: 9377 KGVVTEEKITIVTQREESPPPAVPEIPK-KKVPEERKPVPRKEEEVPPPPKVPALP 9431 Score = 43.9 bits (102), Expect = 3e-04 Identities = 51/216 (23%), Positives = 83/216 (38%), Gaps = 31/216 (14%) Query: 36 QIPELQKSQAA-KEYDLLRKSSEAKEPQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDL 94 ++PE+ K K+ L+ P K+PE P +K K+P+ PP Sbjct: 10720 KVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEV--PKEVVPEKKVAVPKKPEVPPAKVPE 10777 Query: 95 LPWEPPAAWELQEAPAAP---ESLAPPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQ 151 +P +P L+E PA P + +PP + +A E E + P + + Sbjct: 10778 VPKKPV----LEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPE 10833 Query: 152 EPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLEPSNAQEFLELSA------ 205 P + P++P I ++ P ++ E PPP+EP EP E +L Sbjct: 10834 VPPPAVPEEPKKIIPEKKVPVIKKP-------EAPPPKEP-EPEKVIEKPKLKPRPPPPP 10885 Query: 206 -------AQESLEGLIVVETSAASEFPQAPIGLEAT 234 +E + L + E PQ P +E T Sbjct: 10886 PAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELT 10921 Score = 43.1 bits (100), Expect = 5e-04 Identities = 46/175 (26%), Positives = 71/175 (40%), Gaps = 23/175 (13%) Query: 35 AQIPELQKSQAAKEYDLLRKSSEAK-EPQKLPEHMNPPAAWEAQKTP--EFKEPQKPPE- 90 A++PE+ K +E +R E + P K+PE + P +K P K+P+ PP Sbjct: 10467 AKVPEVPKKIVVEEK--VRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPK 10524 Query: 91 ---------PQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTVLEGQGP 141 P+ +P PP + E P P A +K P A IP E P Sbjct: 10525 VPEAPKEVVPEKKVPVPPP---KKPEVPPTKVPEVPKAAVPEKKVPEA--IPPKPESP-P 10578 Query: 142 ANTQDATIAQEPKNSEPQDPPNIEK--PQEAPEYQETAAQLEFLELPPPQEPLEP 194 +A P+ P PP + P + PE + + + +PPP++P P Sbjct: 10579 PEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVP 10633 Score = 42.4 bits (98), Expect = 0.001 Identities = 50/222 (22%), Positives = 90/222 (40%), Gaps = 17/222 (7%) Query: 15 ENEIRQAQVQWLMEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPE-------- 66 E + + +V ++ + A +PE++K K+ + +K E P K+PE Sbjct: 10165 EEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKK--EEAPPAKVPEVPKKVEEK 10222 Query: 67 HMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEA--PAAPESLAPPATRESQ 124 + P E +EP++ P ++ +P EPP+ E++E P PE + Sbjct: 10223 RIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPT 10282 Query: 125 KPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLE 184 P E P + + + + K + P P E P++ PE + + E + Sbjct: 10283 PVPKKVEAPPAKVSK-KIPEEKVPVPVQKKEAPPAKVP--EVPKKVPEKKVLVPKKEAVP 10339 Query: 185 LPPPQEPLEPSNAQEFLELSAAQESLEGLIVVETSAASEFPQ 226 + LE + F + +E LE L VVE + E P+ Sbjct: 10340 PAKGRTVLEEKVSVAFRQEVVVKERLE-LEVVE-AEVEEIPE 10379 Score = 40.8 bits (94), Expect = 0.003 Identities = 45/173 (26%), Positives = 78/173 (45%), Gaps = 18/173 (10%) Query: 37 IPELQKSQAAKEYDLLRKSSEAKEPQKLPEHMNPPAAWEAQKTPEF-KEP---QKPPEPQ 92 +P+ +++ AK ++ +K E K P +P+ PP A K PE K+P +K P P Sbjct: 9967 VPKKKEAPPAKVPEVPKKPEE-KVPVLIPKKEKPPPA----KVPEVPKKPVPEEKVPVPV 10021 Query: 93 DLLPWEPPA-AWELQEAPAAPESLAPPATRESQKPP-MAHEIPTVL--EGQGPANTQDAT 148 PPA E+ + P + + PA ++ + PP E+P L E + P Sbjct: 10022 PKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKV 10081 Query: 149 IAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFL---ELPPPQEPLEPSNAQ 198 A PK + ++P + P P+ +E + E + E+ P +E + P + Sbjct: 10082 EAPPPKVPKKREP--VPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEE 10132 Score = 39.3 bits (90), Expect = 0.008 Identities = 40/172 (23%), Positives = 64/172 (37%), Gaps = 10/172 (5%) Query: 28 EENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPEHMNPPAAWEAQKTPEFKEPQK 87 ++ A A++PE+QK +E + E P +PE E + P +E Sbjct: 9363 KKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVP 9422 Query: 88 PPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTVLE--------GQ 139 PP LP + P E P APP E K + E V E + Sbjct: 9423 PPPKVPALP-KKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQR 9481 Query: 140 GPANTQDATIAQEPKNSEPQDPPNIE-KPQEAPEYQETAAQLEFLELPPPQE 190 + + +E SE ++ +I +E E +E A E+ + P+E Sbjct: 9482 VEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEE 9533 Score = 38.9 bits (89), Expect = 0.010 Identities = 34/140 (24%), Positives = 63/140 (45%), Gaps = 13/140 (9%) Query: 61 PQK-LPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLP------WEPPAAW--ELQEAPAA 111 P+K +PE P + ++ P K P+ P +P++ +P +PP A E+ + P Sbjct: 9954 PRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVP 10013 Query: 112 PESLAPPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAP 171 E + P ++ + PP ++P V + P A + + P P + K + P Sbjct: 10014 EEKVPVPVPKKVEAPPA--KVPEVPKKPVPEKKVPVP-APKKVEAPPAKVPEVPK-KLIP 10069 Query: 172 EYQETAAQLEFLELPPPQEP 191 E ++ + +E PPP+ P Sbjct: 10070 EEKKPTPVPKKVEAPPPKVP 10089 Score = 38.5 bits (88), Expect = 0.013 Identities = 50/200 (25%), Positives = 76/200 (38%), Gaps = 16/200 (8%) Query: 13 KLENEIRQAQVQWLMEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPEHMNPPA 72 ++E E R +V ++E A + ++ E K+ + K P K+ PPA Sbjct: 10408 RVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPA 10467 Query: 73 AW-EAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHE 131 E K +E + PE + P + P +E + PPA + PP E Sbjct: 10468 KVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPE 10527 Query: 132 IP--TVLEGQGPANTQDATIAQEPKNSEPQDPPN--IEKPQEA-PEYQETAAQLEFLELP 186 P V E + P P +P+ PP E P+ A PE + A E P Sbjct: 10528 APKEVVPEKKVPV----------PPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESP 10577 Query: 187 PPQEPLEPSNAQEFLELSAA 206 PP+ P P ++ AA Sbjct: 10578 PPEVPEAPKEVVPEKKVPAA 10597 Score = 38.1 bits (87), Expect = 0.018 Identities = 42/193 (21%), Positives = 82/193 (42%), Gaps = 17/193 (8%) Query: 3 EDLAASYIVLKLENEIRQAQVQWLMEENAALQAQIPELQKSQAAKEYDLLRKSSEAKE-P 61 +++A V ++ E+ +V + E ++ + E ++ +E + + + P Sbjct: 9888 KEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIP 9947 Query: 62 QKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATR 121 K+PE P PE K+P P+ ++ PPA ++ E P PE P Sbjct: 9948 VKVPEVPRKP-------VPEEKKPVPVPKKKE----APPA--KVPEVPKKPEEKVPVLIP 9994 Query: 122 ESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLE 181 + +KPP A ++P V + P + ++ + + P P + K + PE + + Sbjct: 9995 KKEKPPPA-KVPEVPKKPVPEEKVPVPVPKKVE-APPAKVPEVPK-KPVPEKKVPVPAPK 10051 Query: 182 FLELPPPQEPLEP 194 +E PP + P P Sbjct: 10052 KVEAPPAKVPEVP 10064 Score = 38.1 bits (87), Expect = 0.018 Identities = 41/147 (27%), Positives = 56/147 (38%), Gaps = 22/147 (14%) Query: 61 PQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAP---ESLAP 117 P K+PE P AA +K PE P KP P +P P ++ PAAP + P Sbjct: 10550 PTKVPEV--PKAAVPEKKVPE-AIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTP 10606 Query: 118 PATRESQK-----------PPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPN--I 164 E+ K PP E+P + P E +P+ PP Sbjct: 10607 VKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVF 10666 Query: 165 EKPQEAPEYQETAAQLEFLELPPPQEP 191 E+P+E + A E +E P P P Sbjct: 10667 EEPEEVALEEPPA---EVVEEPEPAAP 10690 Score = 38.1 bits (87), Expect = 0.018 Identities = 40/141 (28%), Positives = 57/141 (40%), Gaps = 28/141 (19%) Query: 61 PQKLPEHMNPPAAWEAQKTPEF--KEPQKPP-----EPQDLLPWEPPAAWELQEAPAAPE 113 P K+PE P A +K PE +P+ PP EP+++ EPPA E PE Sbjct: 10634 PTKVPEV--PKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPA-----EVVEEPE 10686 Query: 114 SLAPPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEY 173 APP K P+ P A +A++P+ P P + K + PE Sbjct: 10687 PAAPPQVTVPPKKPV------------PEKKAPAVVAKKPE-LPPVKVPEVPK-EVVPEK 10732 Query: 174 QETAAQLEFLELPPPQEPLEP 194 + + E PP + P P Sbjct: 10733 KVPLVVPKKPEAPPAKVPEVP 10753 Score = 36.2 bits (82), Expect = 0.067 Identities = 44/197 (22%), Positives = 77/197 (39%), Gaps = 15/197 (7%) Query: 18 IRQAQVQWLMEENAALQAQIPELQKSQAAKEYDLLR-KSSEAKEPQKLPEHMNPPAAWEA 76 I++ + E L+ + +Q+ + +EY+ K E EP + + E Sbjct: 9717 IKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREY 9776 Query: 77 QKTPEFKE----PQKP----PEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPP- 127 ++ E +E P+KP P P++ +P +P A A PE P + KPP Sbjct: 9777 ERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPP 9836 Query: 128 --MAHEIPTVLEG--QGPANTQDATIAQEPKNSEPQDPPNIEKPQEAP-EYQETAAQLEF 182 + E V E + ++ EP P P + ++ P +E A + Sbjct: 9837 PKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRV 9896 Query: 183 LELPPPQEPLEPSNAQE 199 E+P EP E + +E Sbjct: 9897 PEVPKELEPEEVAFEEE 9913 Score = 35.8 bits (81), Expect = 0.087 Identities = 40/171 (23%), Positives = 68/171 (39%), Gaps = 14/171 (8%) Query: 26 LMEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPEHMNPPAAWEAQKTPEFKEP 85 ++EE A+ +PE +S + Y+ A E + PE P E ++ PE P Sbjct: 10783 VLEEKPAVP--VPERAESPPPEVYE--EPEEIAPEEEIAPEEEKPVPVAEEEE-PEVPPP 10837 Query: 86 QKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTVLEGQGPANTQ 145 P EP+ ++P + + EAP E P + +KP + P + + Sbjct: 10838 AVPEEPKKIIPEKKVPVIKKPEAPPPKE---PEPEKVIEKPKLKPRPPPPPPAPPKEDVK 10894 Query: 146 DATIAQE--PKNSEPQDPPNIEK----PQEAPEYQETAAQLEFLELPPPQE 190 + + PK P+ P EK P + P ++ +L P P+E Sbjct: 10895 EKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKE 10945 Score = 33.9 bits (76), Expect = 0.33 Identities = 43/211 (20%), Positives = 80/211 (37%), Gaps = 44/211 (20%) Query: 15 ENEIRQAQVQWLMEENA--------ALQAQIPELQKSQAAKEYDLLRKSSE---AKEPQK 63 E E+ + ++++EE A A++ E Q+ + + + K E AK P+ Sbjct: 9524 EYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEA 9583 Query: 64 ----LPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPA 119 +PE P + +K P K P++P +P PE PP Sbjct: 9584 PKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKP-------------------VPEKKVPPK 9624 Query: 120 TRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQ 179 + ++P +P + + TQ+ + E PP P+E + + Sbjct: 9625 VIKMEEP-----LPAKVTERHMQITQEEKVLVAVTKKEA--PPKARVPEEP---KRAVPE 9674 Query: 180 LEFLELPPPQEPLEPSNAQEFLELSAAQESL 210 + L+L P +E P+ EF + +E + Sbjct: 9675 EKVLKLKPKREEEPPAKVTEFRKRVVKEEKV 9705 Score = 33.5 bits (75), Expect = 0.43 Identities = 53/223 (23%), Positives = 87/223 (39%), Gaps = 40/223 (17%) Query: 35 AQIPELQKSQAAKEYDL--LRKSSEAKEPQKLPEHMNP---PAAWEAQKTPEFKEPQKP- 88 A++PE+ K +E + K EA P K+P+ P P A ++ F+E P Sbjct: 10058 AKVPEVPKKLIPEEKKPTPVPKKVEAPPP-KVPKKREPVPVPVALPQEEEVLFEEEIVPE 10116 Query: 89 -----------PEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTVLE 137 PE +++LP E E +E P PE E + PP +P E Sbjct: 10117 EEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIP--PE--------EEEVPPEEEYVP---E 10163 Query: 138 GQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLEPSNA 197 + ++ +PK P P I+K + E + + E E PP + P P Sbjct: 10164 EEEFVPEEEVLPEVKPKVPVPAPVPEIKK--KVTEKKVVIPKKE--EAPPAKVPEVPKKV 10219 Query: 198 QEFLELSAAQESLEGLIVVETS-----AASEFPQAPIGLEATD 235 +E + +E + + V E + E P+ P +E + Sbjct: 10220 EEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVE 10262 Score = 32.7 bits (73), Expect = 0.74 Identities = 33/159 (20%), Positives = 63/159 (39%), Gaps = 13/159 (8%) Query: 81 EFKEPQKPPEPQDLLPWEPPAAWELQE-----APAAPESLAPPATRESQKPPMAHEIPTV 135 E +E ++ E + E P + ++E + A R+ +K + +IP Sbjct: 9512 EEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAK 9571 Query: 136 LEGQGPANTQDATIAQEPKNSEPQDPPNIEK--PQEAPEYQETAAQLEFLELPPP----Q 189 +E PA +A P+ P P EK P + PE E + ++PP + Sbjct: 9572 IEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPE--EPKKPVPEKKVPPKVIKME 9629 Query: 190 EPLEPSNAQEFLELSAAQESLEGLIVVETSAASEFPQAP 228 EPL + ++++ ++ L + E + P+ P Sbjct: 9630 EPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEP 9668 Score = 32.3 bits (72), Expect = 0.96 Identities = 41/168 (24%), Positives = 65/168 (38%), Gaps = 34/168 (20%) Query: 51 LLRKSSEAKEPQKLPEHMN-----------PPAAWEAQKTPEF-KEPQKPPEP---QDLL 95 +LRK E +EP+ P+ + PP E + P K +K PEP ++ Sbjct: 10952 VLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIK 11011 Query: 96 PWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTVLEG---QGPANTQDATIAQE 152 P P A E + P A P E + P+A + + G + A ++A + Sbjct: 11012 PAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKG 11071 Query: 153 PKNSEPQDPPN---------------IEKPQEAP-EYQETAAQLEFLE 184 P P+ P+ + P EAP YQ A L+F++ Sbjct: 11072 PIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVK 11119 Score = 31.6 bits (70), Expect = 1.6 Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 5/81 (6%) Query: 149 IAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLEPSNA-QEFLELSAAQ 207 + +EP ++P+ PP + PE + + L+ PPP+ P EP +E + +S + Sbjct: 9798 VPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITK 9857 Query: 208 ESLEGLIVVETSAASEFPQAP 228 E + T A++ P P Sbjct: 9858 REKEQV----TEPAAKVPMKP 9874 Score = 30.4 bits (67), Expect = 3.7 Identities = 35/151 (23%), Positives = 57/151 (37%), Gaps = 18/151 (11%) Query: 51 LLRKSSEAKEPQKLPEHMNPPAAWEAQK--------TPEFKEPQKPPEPQDLLPWEPPAA 102 LL E K P K E +A+K TP + +KPP P L+P + P Sbjct: 8968 LLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEI 9027 Query: 103 WELQEAPAAPESLAPPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPP 162 ++ + + +E QK E V E + + + + EP D Sbjct: 9028 IDVSSKAEEVKIMTITRKKEVQK-----EKEAVYEKKQAVHKEKRVFIE--SFEEPYDEL 9080 Query: 163 NIE---KPQEAPEYQETAAQLEFLELPPPQE 190 +E +P E P Y+E E +++ +E Sbjct: 9081 EVEPYTEPFEQPYYEEPDEDYEEIKVEAKKE 9111 >gi|112734870 hypothetical protein LOC57648 [Homo sapiens] Length = 1094 Score = 53.1 bits (126), Expect = 5e-07 Identities = 48/182 (26%), Positives = 68/182 (37%), Gaps = 26/182 (14%) Query: 56 SEAKEPQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESL 115 S+ + P + PA + PQ PP PQ L LQE+P + Sbjct: 675 SKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLT-------PLQESPVISKDQ 727 Query: 116 APPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQE 175 +PP + PP H P + P +A A E QDP P APE Q+ Sbjct: 728 SPPPS----PPPSYHPPPP--PTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQD 781 Query: 176 TAAQLEFLELPPPQ---------EPLEPSNAQEFLELSAAQESLEGLIVVETSAASEFPQ 226 L + PPP+ EP PS + E + AA S + ++ + + P Sbjct: 782 ----LSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPP 837 Query: 227 AP 228 AP Sbjct: 838 AP 839 Score = 33.1 bits (74), Expect = 0.57 Identities = 33/140 (23%), Positives = 50/140 (35%), Gaps = 13/140 (9%) Query: 59 KEPQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPP 118 +E + + +PP + P P PP + + E P+A E E P + PP Sbjct: 718 QESPVISKDQSPPPS-----PPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPP 772 Query: 119 ATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAA 178 PP A E + P + P+ + P P + A TA Sbjct: 773 -------PPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATAL 825 Query: 179 QLEFLELP-PPQEPLEPSNA 197 Q++ P PP P P+ A Sbjct: 826 QIQPPGSPDPPPAPPAPAPA 845 Score = 31.6 bits (70), Expect = 1.6 Identities = 53/217 (24%), Positives = 82/217 (37%), Gaps = 34/217 (15%) Query: 61 PQKLPEHM-NPPAAWEAQKTPEFKEPQKPP------EPQDLLPWEPPAAWELQEAPAAPE 113 P K PE + P+A E + P ++P PP E QDL + P E + A+PE Sbjct: 743 PTKKPEVVVEAPSASETAEEP-LQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPE 801 Query: 114 SLAPPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEY 173 P + E P A++ AT Q P PP P A Sbjct: 802 PAGPSGSPELVSSP-------------AASSSSATALQIQPPGSPDPPPAPPAPAPASSA 848 Query: 174 QETAAQLEFLELPPPQEPLEPSNA----QEFLELSAAQESLEGLIVVET-SAASEFPQAP 228 A+L P +EP+ S +E + SL ++ + + A P Sbjct: 849 PGHVAKL------PQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPA 902 Query: 229 IGLEATDFPLQYTLTFSGDSQKLPEFLVQLYSYMRVR 265 +G A PL+ L SG + +P L++ +R++ Sbjct: 903 LGPSAPQKPLRRAL--SGRASPVPAPSSGLHAAVRLK 937 >gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens] Length = 1388 Score = 52.0 bits (123), Expect = 1e-06 Identities = 40/146 (27%), Positives = 74/146 (50%), Gaps = 12/146 (8%) Query: 263 RVRGHLYPTEAALVSFVGNCFSGRAGWWFQLLLDIQSPLLEQCESFIPVLQDTFDNPENM 322 +++G L +E ++F+ + G A WF L +++ PL + +SF+ Q +D+ + Sbjct: 1175 QMKGFLDDSER--MAFLVSLHLGAAERWFILQMEVGEPLSHENKSFLRRSQGIYDSLSEI 1232 Query: 323 KDANQCIHQLCQGEGHV---ATHFHLIAQELNWDESTLWIQFQEGLASSIQDELSH--TS 377 + + QG+ V AT F L+A+ L+W ++ L +F EGL+ ++ ++ Sbjct: 1233 DILSAVLCHPKQGQKSVRQYATDFLLLARHLSWSDAILRTRFLEGLSEAVTTKMGRIFLK 1292 Query: 378 PATNLSDLI-----TQCISLEEKPDP 398 A +L +LI T+C EEK P Sbjct: 1293 VAGSLKELIDRSLYTECQLAEEKDSP 1318 >gi|118200335 family with sequence similarity 127, member A [Homo sapiens] Length = 113 Score = 51.2 bits (121), Expect = 2e-06 Identities = 27/80 (33%), Positives = 44/80 (55%) Query: 237 PLQYTLTFSGDSQKLPEFLVQLYSYMRVRGHLYPTEAALVSFVGNCFSGRAGWWFQLLLD 296 P+ + TF GD+ +LPEF+VQ SYM V + + ++A V+F+ +G A W + Sbjct: 26 PIPFPETFDGDTDRLPEFIVQTGSYMFVDENTFSSDALKVTFLITRLTGPALQWVIPYIK 85 Query: 297 IQSPLLEQCESFIPVLQDTF 316 +SPLL F+ ++ F Sbjct: 86 KESPLLNDYRGFLAEMKRVF 105 >gi|118200337 family with sequence similarity 127, member C [Homo sapiens] Length = 113 Score = 51.2 bits (121), Expect = 2e-06 Identities = 27/80 (33%), Positives = 43/80 (53%) Query: 237 PLQYTLTFSGDSQKLPEFLVQLYSYMRVRGHLYPTEAALVSFVGNCFSGRAGWWFQLLLD 296 P+ + TF GD+ +LPEF+VQ SYM V + + +A V+F+ +G A W + Sbjct: 26 PIPFPETFDGDTDRLPEFIVQTSSYMFVDENTFSNDALKVTFLITRLTGPALQWVIPYIK 85 Query: 297 IQSPLLEQCESFIPVLQDTF 316 +SPLL F+ ++ F Sbjct: 86 KESPLLSDYRGFLAEMKRVF 105 >gi|239757911 PREDICTED: similar to Family with sequence similarity 127, member B [Homo sapiens] Length = 113 Score = 50.8 bits (120), Expect = 3e-06 Identities = 27/80 (33%), Positives = 43/80 (53%) Query: 237 PLQYTLTFSGDSQKLPEFLVQLYSYMRVRGHLYPTEAALVSFVGNCFSGRAGWWFQLLLD 296 P+ + TF GD+ +LPEF+VQ SYM V + + +A V+F+ +G A W + Sbjct: 26 PIPFPETFDGDTDRLPEFIVQTCSYMFVDENTFSNDALKVTFLITRLTGPALQWVIPYIR 85 Query: 297 IQSPLLEQCESFIPVLQDTF 316 +SPLL F+ ++ F Sbjct: 86 KESPLLNDYRGFLAEMKRVF 105 >gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo sapiens] Length = 870 Score = 50.8 bits (120), Expect = 3e-06 Identities = 57/218 (26%), Positives = 85/218 (38%), Gaps = 32/218 (14%) Query: 20 QAQVQWLMEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKL---PEHMNPPAAWEA 76 Q+Q Q L E ++ P + + D SE P + PE NP + Sbjct: 174 QSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDI 233 Query: 77 QKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAP-----ESLAPPATRESQKPP---- 127 Q + + + P + LL EP + QEAPA P ESL P S +PP Sbjct: 234 QSSS--LQQEAPAQLPQLLEEEPSSMQ--QEAPALPPESSMESLTLPNHEVSVQPPGEDQ 289 Query: 128 MAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPP 187 + +P + PA+ + TI EP N E P + PE E +A + + P Sbjct: 290 AYYHLPNITVK--PADVE-VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP 346 Query: 188 P-------------QEPLEPSNAQEFLELSAAQESLEG 212 P Q+P++PS + +E S Q+ G Sbjct: 347 PVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPG 384 Score = 44.7 bits (104), Expect = 2e-04 Identities = 54/215 (25%), Positives = 86/215 (40%), Gaps = 33/215 (15%) Query: 27 MEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPEH----MNPPAAWEAQKTPEF 82 ME ++ Q +Q S++++E + ++ + P + PEH ++PP + Sbjct: 351 MEHELSISEQQQPVQPSESSREVE--SSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSP 408 Query: 83 KEPQKPPEPQDLLPWEPPA----AWELQEAPA----APESLAPPATRESQKPPMAHEIPT 134 KPP+ Q + EP A + QEA A + + PPA + PP+ +P Sbjct: 409 SVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHG-GPPL---LPE 464 Query: 135 VLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLEP 194 E GP Q T Q P +P N E P +P QE AA+ PQ E Sbjct: 465 SSEEAGPLAVQQETSFQSP------EPINNENP--SPTQQEAAAE-------HPQTAEEG 509 Query: 195 SNAQEFLELSAAQESLEGLIVVETSAASEFPQAPI 229 ++ E A ++V + S QA + Sbjct: 510 ESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV 544 Score = 31.2 bits (69), Expect = 2.1 Identities = 34/146 (23%), Positives = 55/146 (37%), Gaps = 21/146 (14%) Query: 79 TPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRE--------SQKPPMAH 130 +P+ + P P + L +P W L E L+ P +++ S P Sbjct: 138 SPQERLPVSPKK----LKKDPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPYPS 193 Query: 131 EIPTVLE---GQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPP 187 +P L + P ++ +Q E Q+P +E Q + QE AQL P Sbjct: 194 SLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQL------P 247 Query: 188 PQEPLEPSNAQEFLELSAAQESLEGL 213 EPS+ Q+ + S+E L Sbjct: 248 QLLEEEPSSMQQEAPALPPESSMESL 273 >gi|118200333 family with sequence similarity 127, member B isoform 1 [Homo sapiens] Length = 113 Score = 50.8 bits (120), Expect = 3e-06 Identities = 27/80 (33%), Positives = 43/80 (53%) Query: 237 PLQYTLTFSGDSQKLPEFLVQLYSYMRVRGHLYPTEAALVSFVGNCFSGRAGWWFQLLLD 296 P+ + TF GD+ +LPEF+VQ SYM V + + +A V+F+ +G A W + Sbjct: 26 PIPFPETFDGDTDRLPEFIVQTSSYMFVDENTFSNDALKVTFLITRLTGPALQWVIPYIR 85 Query: 297 IQSPLLEQCESFIPVLQDTF 316 +SPLL F+ ++ F Sbjct: 86 KESPLLNDYRGFLAEMKRVF 105 >gi|75677612 leucine rich repeat containing 37, member A3 [Homo sapiens] Length = 1634 Score = 50.1 bits (118), Expect = 4e-06 Identities = 57/218 (26%), Positives = 85/218 (38%), Gaps = 32/218 (14%) Query: 20 QAQVQWLMEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKL---PEHMNPPAAWEA 76 Q+Q Q L E ++ P + + D SE P + PE NP + Sbjct: 174 QSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDI 233 Query: 77 QKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAP-----ESLAPPATRESQKPP---- 127 Q + + + P + LL EP + QEAPA P ESL P S +PP Sbjct: 234 QSSS--LQQEAPAQLPQLLEEEPSSMQ--QEAPALPPESSMESLTLPNHEVSVQPPGEDQ 289 Query: 128 MAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPP 187 + +P + PA+ + TI EP N E P + PE E +A + + P Sbjct: 290 AYYHLPNITVK--PADVE-VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP 346 Query: 188 P-------------QEPLEPSNAQEFLELSAAQESLEG 212 P Q+P++PS + +E S Q+ G Sbjct: 347 PVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPG 384 Score = 42.4 bits (98), Expect = 0.001 Identities = 47/183 (25%), Positives = 74/183 (40%), Gaps = 20/183 (10%) Query: 27 MEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPEH----MNPPAAWEAQKTPEF 82 ME ++ Q +Q S++++E + ++ + P + PEH ++PP + Sbjct: 351 MEHELSISEQQQPVQPSESSREVE--SSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASP 408 Query: 83 KEPQKPPEPQDLLPWEPPA----AWELQEAPA----APESLAPPATRESQKPPMAHEIPT 134 KPP+ Q + EP A + QEA + + PPA + PP+ +P Sbjct: 409 SVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG-PPL---LPE 464 Query: 135 VLEGQGPANTQDATIAQ--EPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPL 192 E GP Q T Q EP N+E P E E P+ E + P Q P Sbjct: 465 SSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPE 524 Query: 193 EPS 195 P+ Sbjct: 525 FPN 527 Score = 38.5 bits (88), Expect = 0.013 Identities = 54/231 (23%), Positives = 88/231 (38%), Gaps = 30/231 (12%) Query: 2 VEDLAASYIVLKLENEIRQAQVQWLMEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEP 61 +ED+ +S L+ E Q L EE +++Q + P L + + L + P Sbjct: 230 LEDIQSS----SLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPP 285 Query: 62 QK------LPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESL 115 + LP PA E T E + + Q P + P E P+A + Sbjct: 286 GEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVE----PSATQQE 341 Query: 116 APPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQE 175 AP E PPM HE+ ++ E Q P +++ E P E P + PE+ E Sbjct: 342 API---EPPVPPMEHEL-SISEQQQPVQPSESSREVE------SSPTQQETPGQPPEHHE 391 Query: 176 TA----AQLEFLELPPPQEPLEPSNAQEFLELSAAQESLEGLIVVETSAAS 222 + L P ++P + Q L ++A + G +V A + Sbjct: 392 VTVSPPGHHQTHHLASPSVSVKPPDVQ--LTIAAEPSAEVGTSLVHQEATT 440 Score = 30.0 bits (66), Expect = 4.8 Identities = 34/146 (23%), Positives = 55/146 (37%), Gaps = 21/146 (14%) Query: 79 TPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRE--------SQKPPMAH 130 +P+ + P P + L +P W L E L+ P +++ S P Sbjct: 138 SPQERLPVSPKK----LKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPG 193 Query: 131 EIPTVLE---GQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPP 187 +P L + P ++ +Q E Q+P +E Q + QE AQL P Sbjct: 194 SLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQL------P 247 Query: 188 PQEPLEPSNAQEFLELSAAQESLEGL 213 EPS+ Q+ + S+E L Sbjct: 248 QLLEEEPSSMQQEAPALPPESSMESL 273 Score = 29.6 bits (65), Expect = 6.3 Identities = 42/183 (22%), Positives = 60/183 (32%), Gaps = 37/183 (20%) Query: 71 PAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAP---------ESLAPPATR 121 P W P PPEP W ++ +E+P AP + L P A+ Sbjct: 39 PLEWVKDPLQLTSNPLGPPEP-----WSSHSSHFPRESPHAPTLPADPWDFDHLGPSASS 93 Query: 122 ESQKPPM---------------AHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEK 166 E PP A E+P E Q A+ QD P+ P P ++K Sbjct: 94 EMPAPPQESTENLVPFLDTWDSAGELPLEPE-QFLASQQDLKDKLSPQERLPVSPKKLKK 152 Query: 167 -PQEAPEYQETAAQLEFLELPPPQEPLEPSNAQEFLELSAAQESLEGLIVVETSAASEFP 225 P + E + L P Q+ + E S+ G + E S+ P Sbjct: 153 DPAQRWSLAEIIGIIHQLSTPQSQKQTLQN------EYSSTDTPYPGSLPPELRVKSDEP 206 Query: 226 QAP 228 P Sbjct: 207 PGP 209 >gi|239740955 PREDICTED: similar to c114 SLIT-like testicular protein isoform 1 [Homo sapiens] Length = 1635 Score = 49.7 bits (117), Expect = 6e-06 Identities = 57/218 (26%), Positives = 85/218 (38%), Gaps = 32/218 (14%) Query: 20 QAQVQWLMEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKL---PEHMNPPAAWEA 76 Q+Q Q L E ++ P + + D SE P + PE NP + Sbjct: 174 QSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDI 233 Query: 77 QKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAP-----ESLAPPATRESQKPP---- 127 Q + + + P + LL EP + QEAPA P ESL P S +PP Sbjct: 234 QSSS--LQQEAPAQLPQLLEEEPSSMQ--QEAPALPPESSMESLTLPNHEVSVQPPGEDQ 289 Query: 128 MAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPP 187 + +P + PA+ + TI EP N E P + PE E +A + + P Sbjct: 290 AYYHLPNITVK--PADVE-VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP 346 Query: 188 P-------------QEPLEPSNAQEFLELSAAQESLEG 212 P Q+P++PS + +E S Q+ G Sbjct: 347 PVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPG 384 Score = 41.6 bits (96), Expect = 0.002 Identities = 47/183 (25%), Positives = 73/183 (39%), Gaps = 20/183 (10%) Query: 27 MEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPEH----MNPPAAWEAQKTPEF 82 ME ++ Q +Q S++ +E + ++ + P + PEH ++PP + Sbjct: 351 MEHELSISEQQQPVQPSESPREVE--SSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASP 408 Query: 83 KEPQKPPEPQDLLPWEPPA----AWELQEAPA----APESLAPPATRESQKPPMAHEIPT 134 KPP+ Q + EP A + QEA + + PPA + PP+ +P Sbjct: 409 SVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG-PPL---LPE 464 Query: 135 VLEGQGPANTQDATIAQ--EPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPL 192 E GP Q T Q EP N+E P E E P+ E + P Q P Sbjct: 465 SSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPE 524 Query: 193 EPS 195 P+ Sbjct: 525 FPN 527 Score = 30.0 bits (66), Expect = 4.8 Identities = 34/146 (23%), Positives = 55/146 (37%), Gaps = 21/146 (14%) Query: 79 TPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRE--------SQKPPMAH 130 +P+ + P P + L +P W L E L+ P +++ S P Sbjct: 138 SPQERLPVSPKK----LKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPG 193 Query: 131 EIPTVLE---GQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPP 187 +P L + P ++ +Q E Q+P +E Q + QE AQL P Sbjct: 194 SLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQL------P 247 Query: 188 PQEPLEPSNAQEFLELSAAQESLEGL 213 EPS+ Q+ + S+E L Sbjct: 248 QLLEEEPSSMQQEAPALPPESSMESL 273 Score = 29.6 bits (65), Expect = 6.3 Identities = 42/183 (22%), Positives = 60/183 (32%), Gaps = 37/183 (20%) Query: 71 PAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAP---------ESLAPPATR 121 P W P PPEP W ++ +E+P AP + L P A+ Sbjct: 39 PLEWVKDPLQLTSNPLGPPEP-----WSSHSSHFPRESPHAPTLPADPWDFDHLGPSASS 93 Query: 122 ESQKPPM---------------AHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEK 166 E PP A E+P E Q A+ QD P+ P P ++K Sbjct: 94 EMPAPPQESTENLVPFLDTWDSAGELPLEPE-QFLASQQDLKDKLSPQERLPVSPKKLKK 152 Query: 167 -PQEAPEYQETAAQLEFLELPPPQEPLEPSNAQEFLELSAAQESLEGLIVVETSAASEFP 225 P + E + L P Q+ + E S+ G + E S+ P Sbjct: 153 DPAQRWSLAEIIGIIRQLSTPQSQKQTLQN------EYSSTDTPYPGSLPPELRVKSDEP 206 Query: 226 QAP 228 P Sbjct: 207 PGP 209 >gi|239740953 PREDICTED: similar to c114 SLIT-like testicular protein isoform 2 [Homo sapiens] Length = 1700 Score = 49.7 bits (117), Expect = 6e-06 Identities = 57/218 (26%), Positives = 85/218 (38%), Gaps = 32/218 (14%) Query: 20 QAQVQWLMEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKL---PEHMNPPAAWEA 76 Q+Q Q L E ++ P + + D SE P + PE NP + Sbjct: 174 QSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDI 233 Query: 77 QKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAP-----ESLAPPATRESQKPP---- 127 Q + + + P + LL EP + QEAPA P ESL P S +PP Sbjct: 234 QSSS--LQQEAPAQLPQLLEEEPSSMQ--QEAPALPPESSMESLTLPNHEVSVQPPGEDQ 289 Query: 128 MAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPP 187 + +P + PA+ + TI EP N E P + PE E +A + + P Sbjct: 290 AYYHLPNITVK--PADVE-VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP 346 Query: 188 P-------------QEPLEPSNAQEFLELSAAQESLEG 212 P Q+P++PS + +E S Q+ G Sbjct: 347 PVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPG 384 Score = 41.6 bits (96), Expect = 0.002 Identities = 47/183 (25%), Positives = 73/183 (39%), Gaps = 20/183 (10%) Query: 27 MEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPEH----MNPPAAWEAQKTPEF 82 ME ++ Q +Q S++ +E + ++ + P + PEH ++PP + Sbjct: 351 MEHELSISEQQQPVQPSESPREVE--SSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASP 408 Query: 83 KEPQKPPEPQDLLPWEPPA----AWELQEAPA----APESLAPPATRESQKPPMAHEIPT 134 KPP+ Q + EP A + QEA + + PPA + PP+ +P Sbjct: 409 SVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG-PPL---LPE 464 Query: 135 VLEGQGPANTQDATIAQ--EPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPL 192 E GP Q T Q EP N+E P E E P+ E + P Q P Sbjct: 465 SSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPE 524 Query: 193 EPS 195 P+ Sbjct: 525 FPN 527 Score = 30.0 bits (66), Expect = 4.8 Identities = 34/146 (23%), Positives = 55/146 (37%), Gaps = 21/146 (14%) Query: 79 TPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRE--------SQKPPMAH 130 +P+ + P P + L +P W L E L+ P +++ S P Sbjct: 138 SPQERLPVSPKK----LKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPG 193 Query: 131 EIPTVLE---GQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPP 187 +P L + P ++ +Q E Q+P +E Q + QE AQL P Sbjct: 194 SLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQL------P 247 Query: 188 PQEPLEPSNAQEFLELSAAQESLEGL 213 EPS+ Q+ + S+E L Sbjct: 248 QLLEEEPSSMQQEAPALPPESSMESL 273 Score = 29.6 bits (65), Expect = 6.3 Identities = 42/183 (22%), Positives = 60/183 (32%), Gaps = 37/183 (20%) Query: 71 PAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAP---------ESLAPPATR 121 P W P PPEP W ++ +E+P AP + L P A+ Sbjct: 39 PLEWVKDPLQLTSNPLGPPEP-----WSSHSSHFPRESPHAPTLPADPWDFDHLGPSASS 93 Query: 122 ESQKPPM---------------AHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEK 166 E PP A E+P E Q A+ QD P+ P P ++K Sbjct: 94 EMPAPPQESTENLVPFLDTWDSAGELPLEPE-QFLASQQDLKDKLSPQERLPVSPKKLKK 152 Query: 167 -PQEAPEYQETAAQLEFLELPPPQEPLEPSNAQEFLELSAAQESLEGLIVVETSAASEFP 225 P + E + L P Q+ + E S+ G + E S+ P Sbjct: 153 DPAQRWSLAEIIGIIRQLSTPQSQKQTLQN------EYSSTDTPYPGSLPPELRVKSDEP 206 Query: 226 QAP 228 P Sbjct: 207 PGP 209 >gi|116325993 c114 SLIT-like testicular protein [Homo sapiens] Length = 1700 Score = 49.7 bits (117), Expect = 6e-06 Identities = 57/218 (26%), Positives = 85/218 (38%), Gaps = 32/218 (14%) Query: 20 QAQVQWLMEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKL---PEHMNPPAAWEA 76 Q+Q Q L E ++ P + + D SE P + PE NP + Sbjct: 174 QSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDI 233 Query: 77 QKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAP-----ESLAPPATRESQKPP---- 127 Q + + + P + LL EP + QEAPA P ESL P S +PP Sbjct: 234 QSSS--LQQEAPAQLPQLLEEEPSSMQ--QEAPALPPESSMESLTLPNHEVSVQPPGEDQ 289 Query: 128 MAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPP 187 + +P + PA+ + TI EP N E P + PE E +A + + P Sbjct: 290 AYYHLPNITVK--PADVE-VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP 346 Query: 188 P-------------QEPLEPSNAQEFLELSAAQESLEG 212 P Q+P++PS + +E S Q+ G Sbjct: 347 PVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPG 384 Score = 41.6 bits (96), Expect = 0.002 Identities = 47/183 (25%), Positives = 73/183 (39%), Gaps = 20/183 (10%) Query: 27 MEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPEH----MNPPAAWEAQKTPEF 82 ME ++ Q +Q S++ +E + ++ + P + PEH ++PP + Sbjct: 351 MEHELSISEQQQPVQPSESPREVE--SSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASP 408 Query: 83 KEPQKPPEPQDLLPWEPPA----AWELQEAPA----APESLAPPATRESQKPPMAHEIPT 134 KPP+ Q + EP A + QEA + + PPA + PP+ +P Sbjct: 409 SVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG-PPL---LPE 464 Query: 135 VLEGQGPANTQDATIAQ--EPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPL 192 E GP Q T Q EP N+E P E E P+ E + P Q P Sbjct: 465 SSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPE 524 Query: 193 EPS 195 P+ Sbjct: 525 FPN 527 Score = 30.8 bits (68), Expect = 2.8 Identities = 34/146 (23%), Positives = 55/146 (37%), Gaps = 21/146 (14%) Query: 79 TPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRE--------SQKPPMAH 130 +P+ + P P + L +P W L E L+ P +++ S P Sbjct: 138 SPQERLPVSPKK----LKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPG 193 Query: 131 EIPTVLE---GQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPP 187 +P L + P ++ +Q E Q+P +E Q + QE AQL P Sbjct: 194 SLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQL------P 247 Query: 188 PQEPLEPSNAQEFLELSAAQESLEGL 213 EPS+ Q+ + S+E L Sbjct: 248 QLLEEEPSSMQQEAPALPPESSMESL 273 >gi|110665701 leucine rich repeat containing 37A [Homo sapiens] Length = 1700 Score = 49.7 bits (117), Expect = 6e-06 Identities = 57/218 (26%), Positives = 85/218 (38%), Gaps = 32/218 (14%) Query: 20 QAQVQWLMEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKL---PEHMNPPAAWEA 76 Q+Q Q L E ++ P + + D SE P + PE NP + Sbjct: 174 QSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDI 233 Query: 77 QKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAP-----ESLAPPATRESQKPP---- 127 Q + + + P + LL EP + QEAPA P ESL P S +PP Sbjct: 234 QSSS--LQQEAPAQLPQLLEEEPSSMQ--QEAPALPPESSMESLTLPNHEVSVQPPGEDQ 289 Query: 128 MAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPP 187 + +P + PA+ + TI EP N E P + PE E +A + + P Sbjct: 290 AYYHLPNITVK--PADVE-VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP 346 Query: 188 P-------------QEPLEPSNAQEFLELSAAQESLEG 212 P Q+P++PS + +E S Q+ G Sbjct: 347 PVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPG 384 Score = 41.6 bits (96), Expect = 0.002 Identities = 47/183 (25%), Positives = 73/183 (39%), Gaps = 20/183 (10%) Query: 27 MEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPEH----MNPPAAWEAQKTPEF 82 ME ++ Q +Q S++ +E + ++ + P + PEH ++PP + Sbjct: 351 MEHELSISEQQQPVQPSESPREVE--SSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASP 408 Query: 83 KEPQKPPEPQDLLPWEPPA----AWELQEAPA----APESLAPPATRESQKPPMAHEIPT 134 KPP+ Q + EP A + QEA + + PPA + PP+ +P Sbjct: 409 SVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG-PPL---LPE 464 Query: 135 VLEGQGPANTQDATIAQ--EPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPL 192 E GP Q T Q EP N+E P E E P+ E + P Q P Sbjct: 465 SSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPE 524 Query: 193 EPS 195 P+ Sbjct: 525 FPN 527 Score = 30.8 bits (68), Expect = 2.8 Identities = 34/146 (23%), Positives = 55/146 (37%), Gaps = 21/146 (14%) Query: 79 TPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRE--------SQKPPMAH 130 +P+ + P P + L +P W L E L+ P +++ S P Sbjct: 138 SPQERLPVSPKK----LKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPG 193 Query: 131 EIPTVLE---GQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPP 187 +P L + P ++ +Q E Q+P +E Q + QE AQL P Sbjct: 194 SLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQL------P 247 Query: 188 PQEPLEPSNAQEFLELSAAQESLEGL 213 EPS+ Q+ + S+E L Sbjct: 248 QLLEEEPSSMQQEAPALPPESSMESL 273 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 49.3 bits (116), Expect = 8e-06 Identities = 53/213 (24%), Positives = 84/213 (39%), Gaps = 21/213 (9%) Query: 28 EENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPEHMNPPAAWEAQKTPEFKEPQK 87 E ++ ++ + + S+ +K +E +K H + + Q+ P Q Sbjct: 702 ESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQ----QMQQAPAPVPQQP 757 Query: 88 PPEPQDLLPWEPPAAWELQEAPAAPESL---APPATRESQKPPMAHEIPTVLEGQGPANT 144 PP PQ P PP + P P S+ A PA + S P +A ++P VLE Q P + Sbjct: 758 PPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVP-VLEPQLPGSV 816 Query: 145 QD------ATIAQEPKNSEPQDPPNIEKPQE--APEY--QETAAQLEFLELPPPQEPLEP 194 D I P +P+ PP++ +P E P + Q L PQ+P P Sbjct: 817 FDPIGHFTQPILHLP---QPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRP 873 Query: 195 SNAQEFLELSAAQESLEGLIVVETSAASEFPQA 227 SN L A+ + +T + P A Sbjct: 874 SNRAAALPPKPARPPAVSPALTQTPLLPQPPMA 906 Score = 37.4 bits (85), Expect = 0.030 Identities = 41/157 (26%), Positives = 57/157 (36%), Gaps = 30/157 (19%) Query: 43 SQAAKEYDLLRKSSEAKEPQKLPEHMNPPA-----------AWEAQKT-------PEFKE 84 S A + LL + A+ PQ L E PPA + QK P K Sbjct: 891 SPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKV 950 Query: 85 PQKPPEPQDLLPWEPPAAWELQE--APAAPESLAPPATRESQKPPMAHEIPTVLEGQGPA 142 +PP P P P +LQ+ P P PP ++ Q PP + + Sbjct: 951 QSQPPPPLPPPP-HPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPM------- 1002 Query: 143 NTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQ 179 Q +T Q+P + Q PP+ Q+ P Q Q Sbjct: 1003 --QFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQ 1037 Score = 37.4 bits (85), Expect = 0.030 Identities = 46/192 (23%), Positives = 70/192 (36%), Gaps = 15/192 (7%) Query: 33 LQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQ 92 +Q + +LQK Q L +++ P LP +P + Q+ P P +P P Sbjct: 928 MQLYLQQLQKVQPPTPL-LPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPP 986 Query: 93 DLLPWEPPAAWELQEAPAAPESLAPPATRESQ--KPPMAHEIPTVLEGQGPANTQDATIA 150 PP LQ + PP + Q PP + P PA Q Sbjct: 987 QQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPP----PQPAKPQQVIQH 1042 Query: 151 QEPKNSEPQDPPNIEKPQEAPE----YQETAAQLEFL-ELPPPQEPLEPSNAQEFLELSA 205 DP + +EAP + +Q + L PPQ+ ++P QE S Sbjct: 1043 HHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKK-QELRAASV 1101 Query: 206 AQESLEGLIVVE 217 Q + L+VV+ Sbjct: 1102 VQP--QPLVVVK 1111 Score = 35.4 bits (80), Expect = 0.11 Identities = 37/133 (27%), Positives = 48/133 (36%), Gaps = 16/133 (12%) Query: 64 LPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRES 123 LP+ PP P+ E PP PPA A P+ + P+ R + Sbjct: 830 LPQPELPP------HLPQPPEHSTPPHLNQHAVVSPPALHN-----ALPQQPSRPSNRAA 878 Query: 124 QKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAP-EYQETAAQLEF 182 PP P V PA TQ + Q P PQ E+P P + L+ Sbjct: 879 ALPPKPARPPAV----SPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQ 934 Query: 183 LELPPPQEPLEPS 195 L+ P PL PS Sbjct: 935 LQKVQPPTPLLPS 947 >gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo sapiens] Length = 756 Score = 48.1 bits (113), Expect = 2e-05 Identities = 47/179 (26%), Positives = 76/179 (42%), Gaps = 16/179 (8%) Query: 38 PELQKSQAAKEYDLLR---KSSEAKEPQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDL 94 PEL + + + D+ S EA + K P++ E TPE PQ PP + Sbjct: 488 PELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAHTPEAPPPQ-PPSSERC 546 Query: 95 LPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPK 154 L +P E + PA+R + + P HE T L + P+N + + Sbjct: 547 LGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEEAPSN--------DER 598 Query: 155 NSEPQDPPNIEKP-QEAPEYQETAAQLEFLELP---PPQEPLEPSNAQEFLELSAAQES 209 E + PPN ++P +E +E A E + L PP+E + P +E + AQ++ Sbjct: 599 TPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEVAPKEEVPPIERAFAQKT 657 Score = 32.0 bits (71), Expect = 1.3 Identities = 33/138 (23%), Positives = 50/138 (36%), Gaps = 21/138 (15%) Query: 61 PQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPAT 120 P K PPA A + + P K P P+ L + + P Sbjct: 356 PDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTL--------------TLGDKASIPGN 401 Query: 121 RESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNS-EPQDPPNIEKPQEAPEYQETAAQ 179 S K P ++PT + P + A P+NS P++ ++KP PE + + Sbjct: 402 STSGKIPAPDKVPTPEKMVTPEDK-----ASIPENSIIPEETLTVDKP-STPERVFSVEE 455 Query: 180 LEFLELPPPQEPLEPSNA 197 LE PP + P A Sbjct: 456 SPALEAPPMDKVPNPKMA 473 >gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo sapiens] Length = 645 Score = 48.1 bits (113), Expect = 2e-05 Identities = 47/179 (26%), Positives = 76/179 (42%), Gaps = 16/179 (8%) Query: 38 PELQKSQAAKEYDLLR---KSSEAKEPQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDL 94 PEL + + + D+ S EA + K P++ E TPE PQ PP + Sbjct: 377 PELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAHTPEAPPPQ-PPSSERC 435 Query: 95 LPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPK 154 L +P E + PA+R + + P HE T L + P+N + + Sbjct: 436 LGEMKCTLVRGDSSPRQAELKSGPASRPALEKPHPHEEATTLPEEAPSN--------DER 487 Query: 155 NSEPQDPPNIEKP-QEAPEYQETAAQLEFLELP---PPQEPLEPSNAQEFLELSAAQES 209 E + PPN ++P +E +E A E + L PP+E + P +E + AQ++ Sbjct: 488 TPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEVAPKEEVPPIERAFAQKT 546 Score = 32.0 bits (71), Expect = 1.3 Identities = 33/138 (23%), Positives = 50/138 (36%), Gaps = 21/138 (15%) Query: 61 PQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPAT 120 P K PPA A + + P K P P+ L + + P Sbjct: 245 PDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTL--------------TLGDKASIPGN 290 Query: 121 RESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNS-EPQDPPNIEKPQEAPEYQETAAQ 179 S K P ++PT + P + A P+NS P++ ++KP PE + + Sbjct: 291 STSGKIPAPDKVPTPEKMVTPEDK-----ASIPENSIIPEETLTVDKP-STPERVFSVEE 344 Query: 180 LEFLELPPPQEPLEPSNA 197 LE PP + P A Sbjct: 345 SPALEAPPMDKVPNPKMA 362 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 47.8 bits (112), Expect = 2e-05 Identities = 39/146 (26%), Positives = 54/146 (36%), Gaps = 10/146 (6%) Query: 59 KEPQKL-PEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAP 117 KEP P+ P E T + P P EP P +P + AP P+ AP Sbjct: 315 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 374 Query: 118 -------PATRESQKPPMAHEIPTVLEGQGPANTQDA-TIAQEPKNSEPQDPPNIEKPQE 169 P T + P PT + P T+ A T +EP + ++P + Sbjct: 375 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 434 Query: 170 APEYQETAAQLEFLELPPPQEPLEPS 195 AP + A E P P P EP+ Sbjct: 435 APTTPKKPAPTTPKE-PAPTTPKEPA 459 Score = 47.4 bits (111), Expect = 3e-05 Identities = 45/176 (25%), Positives = 64/176 (36%), Gaps = 30/176 (17%) Query: 41 QKSQAAKEYDLLRKSS--EAKEPQKLPEHMNPPAAWE----AQKTPEFKEPQKPPEPQDL 94 +K+ +AKE + K+S + K+ P A A TP+ P P EP Sbjct: 168 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAST 227 Query: 95 LPWEP--------------PAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTVLEGQG 140 P EP PA + AP P+ AP T+E PT + Sbjct: 228 TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA 287 Query: 141 PANTQDA-TIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLEPS 195 P T+ A T +EP + P+ P + AP + P P P EP+ Sbjct: 288 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---------PTPTTPKEPA 334 Score = 45.1 bits (105), Expect = 1e-04 Identities = 34/122 (27%), Positives = 47/122 (38%), Gaps = 3/122 (2%) Query: 76 AQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTV 135 A TP+ P P EP P EP + AP P+ AP +E+ PT Sbjct: 435 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 494 Query: 136 LEGQGPANTQD--ATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLE 193 E P + T +E + P++P + AP + AA E P P P E Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-PAPTTPKE 553 Query: 194 PS 195 P+ Sbjct: 554 PA 555 Score = 43.5 bits (101), Expect = 4e-04 Identities = 39/147 (26%), Positives = 51/147 (34%), Gaps = 17/147 (11%) Query: 65 PEHMNPPAAWE-AQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAP------ 117 PE P E A TP+ P P EP P EP + AP P+ AP Sbjct: 519 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 578 Query: 118 -------PATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDP--PNIEKPQ 168 PA +KP PT + + + T D PK + P P P P+ Sbjct: 579 APTTLKEPAPTTPKKPAPKELAPTTTK-EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 637 Query: 169 EAPEYQETAAQLEFLELPPPQEPLEPS 195 E L+ P P P +P+ Sbjct: 638 EPAPTTPKGTAPTTLKEPAPTTPKKPA 664 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/146 (26%), Positives = 51/146 (34%), Gaps = 7/146 (4%) Query: 59 KEPQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPP 118 KEP P E T P P EP EP + AP P+ AP Sbjct: 386 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 445 Query: 119 ATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNI--EKPQE-APEYQE 175 +E PT + P ++ PK + P P + P++ AP E Sbjct: 446 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTTPE 504 Query: 176 TAAQLEFLELPP--PQEPLEPSNAQE 199 A EL P P+EP P+ +E Sbjct: 505 KPAPTTPEELAPTTPEEP-TPTTPEE 529 Score = 40.4 bits (93), Expect = 0.004 Identities = 37/143 (25%), Positives = 51/143 (35%), Gaps = 13/143 (9%) Query: 55 SSEAKEPQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPES 114 S+ KEP P E T P P EP EP AP P+ Sbjct: 226 STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP--------APTTPKE 277 Query: 115 LAPPATRESQKPPMAHEIPTVLEGQGPANTQD--ATIAQEPKNSEPQDPPNIEKPQEAPE 172 AP T+E P PT + P + T +EP + P++P + AP Sbjct: 278 PAPTTTKE-PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 336 Query: 173 YQETAAQLEFLELPPPQEPLEPS 195 +E A + P P P +P+ Sbjct: 337 TKEPAPTTP--KEPAPTAPKKPA 357 Score = 38.9 bits (89), Expect = 0.010 Identities = 40/144 (27%), Positives = 49/144 (34%), Gaps = 15/144 (10%) Query: 61 PQKL----PEHMNPPAAWE-AQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESL 115 P+KL PE P E A TPE P P EP P + AP P+ Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 554 Query: 116 APPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDP-PNIEKPQEAPEYQ 174 AP +E PT +G P T +EP + P+ P P P E Sbjct: 555 APTTPKEPAPTTPKETAPTTPKGTAP------TTLKEPAPTTPKKPAPKELAPTTTKEPT 608 Query: 175 ETAAQLEFLELP---PPQEPLEPS 195 T P P P EP+ Sbjct: 609 STTCDKPAPTTPKGTAPTTPKEPA 632 Score = 37.7 bits (86), Expect = 0.023 Identities = 38/138 (27%), Positives = 48/138 (34%), Gaps = 17/138 (12%) Query: 59 KEPQKL-PEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAP 117 KEP P+ P E T P P EP P +P AP P+ AP Sbjct: 268 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP--------APTTPKEPAP 319 Query: 118 PATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETA 177 +E PT E PA T +EP + P+ P + AP + Sbjct: 320 TTPKEPTPTTPKEPAPTTKE---PA----PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 372 Query: 178 AQLEFLELPPPQEPLEPS 195 A E P P P EP+ Sbjct: 373 APTTTKE-PSPTTPKEPA 389 Score = 36.2 bits (82), Expect = 0.067 Identities = 32/107 (29%), Positives = 43/107 (40%), Gaps = 15/107 (14%) Query: 76 AQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTV 135 A TP+ P P EP P +P AP PE+ PP T E P E PT Sbjct: 685 APTTPKETAPTTPKEPAPTTPKKP--------APTTPET-PPPTTSEVSTPTTTKE-PTT 734 Query: 136 LEGQGPANTQDATIAQEPK--NSEPQDP--PNIEKPQEA-PEYQETA 177 + +T + + PK + P++P P + P PE TA Sbjct: 735 IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA 781 Score = 35.8 bits (81), Expect = 0.087 Identities = 35/142 (24%), Positives = 48/142 (33%), Gaps = 17/142 (11%) Query: 59 KEPQKLPEHMNPPAAWEAQKTPEFKEPQ----KPPEPQDLLPW---EPPAAWELQEAPAA 111 KEP P + KEP K P P++L P EP + + AP Sbjct: 560 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 619 Query: 112 PESLAPPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAP 171 P+ AP +E PT +G P T +EP + P+ P P+E Sbjct: 620 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAP------TTLKEPAPTTPKKP----APKELA 669 Query: 172 EYQETAAQLEFLELPPPQEPLE 193 + P P P E Sbjct: 670 PTTTKGPTSTTSDKPAPTTPKE 691 Score = 33.5 bits (75), Expect = 0.43 Identities = 34/117 (29%), Positives = 45/117 (38%), Gaps = 16/117 (13%) Query: 59 KEPQKLPEHMNPPAAWEAQKTPEFKEPQ----KPPEPQDLLPWE---PPAAWELQEAPAA 111 KEP P + KEP K P P++L P P + + AP Sbjct: 629 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 688 Query: 112 PESLAP-----PATRESQKP-PMAHEI--PTVLEGQGPANTQD-ATIAQEPKNSEPQ 159 P+ AP PA +KP P E PT E P T++ TI + P S P+ Sbjct: 689 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 745 Score = 32.3 bits (72), Expect = 0.96 Identities = 31/117 (26%), Positives = 43/117 (36%), Gaps = 15/117 (12%) Query: 79 TPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTVLEG 138 TPE P P +P P E + P PE A P T ++ P E Sbjct: 494 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA-PTTPKAAAPNTPKE------- 545 Query: 139 QGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLEPS 195 PA T +EP + P++P + AP + A E P P P +P+ Sbjct: 546 --PA----PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE-PAPTTPKKPA 595 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 47.8 bits (112), Expect = 2e-05 Identities = 39/146 (26%), Positives = 54/146 (36%), Gaps = 10/146 (6%) Query: 59 KEPQKL-PEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAP 117 KEP P+ P E T + P P EP P +P + AP P+ AP Sbjct: 356 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 415 Query: 118 -------PATRESQKPPMAHEIPTVLEGQGPANTQDA-TIAQEPKNSEPQDPPNIEKPQE 169 P T + P PT + P T+ A T +EP + ++P + Sbjct: 416 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 475 Query: 170 APEYQETAAQLEFLELPPPQEPLEPS 195 AP + A E P P P EP+ Sbjct: 476 APTTPKKPAPTTPKE-PAPTTPKEPA 500 Score = 47.4 bits (111), Expect = 3e-05 Identities = 45/176 (25%), Positives = 64/176 (36%), Gaps = 30/176 (17%) Query: 41 QKSQAAKEYDLLRKSS--EAKEPQKLPEHMNPPAAWE----AQKTPEFKEPQKPPEPQDL 94 +K+ +AKE + K+S + K+ P A A TP+ P P EP Sbjct: 209 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAST 268 Query: 95 LPWEP--------------PAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTVLEGQG 140 P EP PA + AP P+ AP T+E PT + Sbjct: 269 TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA 328 Query: 141 PANTQDA-TIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLEPS 195 P T+ A T +EP + P+ P + AP + P P P EP+ Sbjct: 329 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---------PTPTTPKEPA 375 Score = 45.1 bits (105), Expect = 1e-04 Identities = 34/122 (27%), Positives = 47/122 (38%), Gaps = 3/122 (2%) Query: 76 AQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTV 135 A TP+ P P EP P EP + AP P+ AP +E+ PT Sbjct: 476 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 535 Query: 136 LEGQGPANTQD--ATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLE 193 E P + T +E + P++P + AP + AA E P P P E Sbjct: 536 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-PAPTTPKE 594 Query: 194 PS 195 P+ Sbjct: 595 PA 596 Score = 43.5 bits (101), Expect = 4e-04 Identities = 39/147 (26%), Positives = 51/147 (34%), Gaps = 17/147 (11%) Query: 65 PEHMNPPAAWE-AQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAP------ 117 PE P E A TP+ P P EP P EP + AP P+ AP Sbjct: 560 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 619 Query: 118 -------PATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDP--PNIEKPQ 168 PA +KP PT + + + T D PK + P P P P+ Sbjct: 620 APTTLKEPAPTTPKKPAPKELAPTTTK-EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 678 Query: 169 EAPEYQETAAQLEFLELPPPQEPLEPS 195 E L+ P P P +P+ Sbjct: 679 EPAPTTPKGTAPTTLKEPAPTTPKKPA 705 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/146 (26%), Positives = 51/146 (34%), Gaps = 7/146 (4%) Query: 59 KEPQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPP 118 KEP P E T P P EP EP + AP P+ AP Sbjct: 427 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 486 Query: 119 ATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNI--EKPQE-APEYQE 175 +E PT + P ++ PK + P P + P++ AP E Sbjct: 487 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTTPE 545 Query: 176 TAAQLEFLELPP--PQEPLEPSNAQE 199 A EL P P+EP P+ +E Sbjct: 546 KPAPTTPEELAPTTPEEP-TPTTPEE 570 Score = 40.4 bits (93), Expect = 0.004 Identities = 37/143 (25%), Positives = 51/143 (35%), Gaps = 13/143 (9%) Query: 55 SSEAKEPQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPES 114 S+ KEP P E T P P EP EP AP P+ Sbjct: 267 STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP--------APTTPKE 318 Query: 115 LAPPATRESQKPPMAHEIPTVLEGQGPANTQD--ATIAQEPKNSEPQDPPNIEKPQEAPE 172 AP T+E P PT + P + T +EP + P++P + AP Sbjct: 319 PAPTTTKE-PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 377 Query: 173 YQETAAQLEFLELPPPQEPLEPS 195 +E A + P P P +P+ Sbjct: 378 TKEPAPTTP--KEPAPTAPKKPA 398 Score = 38.9 bits (89), Expect = 0.010 Identities = 40/144 (27%), Positives = 49/144 (34%), Gaps = 15/144 (10%) Query: 61 PQKL----PEHMNPPAAWE-AQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESL 115 P+KL PE P E A TPE P P EP P + AP P+ Sbjct: 536 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 595 Query: 116 APPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDP-PNIEKPQEAPEYQ 174 AP +E PT +G P T +EP + P+ P P P E Sbjct: 596 APTTPKEPAPTTPKETAPTTPKGTAP------TTLKEPAPTTPKKPAPKELAPTTTKEPT 649 Query: 175 ETAAQLEFLELP---PPQEPLEPS 195 T P P P EP+ Sbjct: 650 STTCDKPAPTTPKGTAPTTPKEPA 673 Score = 37.7 bits (86), Expect = 0.023 Identities = 38/138 (27%), Positives = 48/138 (34%), Gaps = 17/138 (12%) Query: 59 KEPQKL-PEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAP 117 KEP P+ P E T P P EP P +P AP P+ AP Sbjct: 309 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP--------APTTPKEPAP 360 Query: 118 PATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETA 177 +E PT E PA T +EP + P+ P + AP + Sbjct: 361 TTPKEPTPTTPKEPAPTTKE---PA----PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 413 Query: 178 AQLEFLELPPPQEPLEPS 195 A E P P P EP+ Sbjct: 414 APTTTKE-PSPTTPKEPA 430 Score = 36.2 bits (82), Expect = 0.067 Identities = 32/107 (29%), Positives = 43/107 (40%), Gaps = 15/107 (14%) Query: 76 AQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTV 135 A TP+ P P EP P +P AP PE+ PP T E P E PT Sbjct: 726 APTTPKETAPTTPKEPAPTTPKKP--------APTTPET-PPPTTSEVSTPTTTKE-PTT 775 Query: 136 LEGQGPANTQDATIAQEPK--NSEPQDP--PNIEKPQEA-PEYQETA 177 + +T + + PK + P++P P + P PE TA Sbjct: 776 IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA 822 Score = 35.8 bits (81), Expect = 0.087 Identities = 35/142 (24%), Positives = 48/142 (33%), Gaps = 17/142 (11%) Query: 59 KEPQKLPEHMNPPAAWEAQKTPEFKEPQ----KPPEPQDLLPW---EPPAAWELQEAPAA 111 KEP P + KEP K P P++L P EP + + AP Sbjct: 601 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 660 Query: 112 PESLAPPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAP 171 P+ AP +E PT +G P T +EP + P+ P P+E Sbjct: 661 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAP------TTLKEPAPTTPKKP----APKELA 710 Query: 172 EYQETAAQLEFLELPPPQEPLE 193 + P P P E Sbjct: 711 PTTTKGPTSTTSDKPAPTTPKE 732 Score = 33.5 bits (75), Expect = 0.43 Identities = 34/117 (29%), Positives = 45/117 (38%), Gaps = 16/117 (13%) Query: 59 KEPQKLPEHMNPPAAWEAQKTPEFKEPQ----KPPEPQDLLPWE---PPAAWELQEAPAA 111 KEP P + KEP K P P++L P P + + AP Sbjct: 670 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 729 Query: 112 PESLAP-----PATRESQKP-PMAHEI--PTVLEGQGPANTQD-ATIAQEPKNSEPQ 159 P+ AP PA +KP P E PT E P T++ TI + P S P+ Sbjct: 730 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 786 Score = 32.3 bits (72), Expect = 0.96 Identities = 31/117 (26%), Positives = 43/117 (36%), Gaps = 15/117 (12%) Query: 79 TPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTVLEG 138 TPE P P +P P E + P PE A P T ++ P E Sbjct: 535 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA-PTTPKAAAPNTPKE------- 586 Query: 139 QGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLEPS 195 PA T +EP + P++P + AP + A E P P P +P+ Sbjct: 587 --PA----PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE-PAPTTPKKPA 636 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 47.8 bits (112), Expect = 2e-05 Identities = 39/146 (26%), Positives = 54/146 (36%), Gaps = 10/146 (6%) Query: 59 KEPQKL-PEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAP 117 KEP P+ P E T + P P EP P +P + AP P+ AP Sbjct: 408 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 467 Query: 118 -------PATRESQKPPMAHEIPTVLEGQGPANTQDA-TIAQEPKNSEPQDPPNIEKPQE 169 P T + P PT + P T+ A T +EP + ++P + Sbjct: 468 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 527 Query: 170 APEYQETAAQLEFLELPPPQEPLEPS 195 AP + A E P P P EP+ Sbjct: 528 APTTPKKPAPTTPKE-PAPTTPKEPA 552 Score = 47.4 bits (111), Expect = 3e-05 Identities = 45/176 (25%), Positives = 64/176 (36%), Gaps = 30/176 (17%) Query: 41 QKSQAAKEYDLLRKSS--EAKEPQKLPEHMNPPAAWE----AQKTPEFKEPQKPPEPQDL 94 +K+ +AKE + K+S + K+ P A A TP+ P P EP Sbjct: 261 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAST 320 Query: 95 LPWEP--------------PAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTVLEGQG 140 P EP PA + AP P+ AP T+E PT + Sbjct: 321 TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA 380 Query: 141 PANTQDA-TIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLEPS 195 P T+ A T +EP + P+ P + AP + P P P EP+ Sbjct: 381 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---------PTPTTPKEPA 427 Score = 45.1 bits (105), Expect = 1e-04 Identities = 34/122 (27%), Positives = 47/122 (38%), Gaps = 3/122 (2%) Query: 76 AQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTV 135 A TP+ P P EP P EP + AP P+ AP +E+ PT Sbjct: 528 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 587 Query: 136 LEGQGPANTQD--ATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLE 193 E P + T +E + P++P + AP + AA E P P P E Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-PAPTTPKE 646 Query: 194 PS 195 P+ Sbjct: 647 PA 648 Score = 43.5 bits (101), Expect = 4e-04 Identities = 39/147 (26%), Positives = 51/147 (34%), Gaps = 17/147 (11%) Query: 65 PEHMNPPAAWE-AQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAP------ 117 PE P E A TP+ P P EP P EP + AP P+ AP Sbjct: 612 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 671 Query: 118 -------PATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDP--PNIEKPQ 168 PA +KP PT + + + T D PK + P P P P+ Sbjct: 672 APTTLKEPAPTTPKKPAPKELAPTTTK-EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 730 Query: 169 EAPEYQETAAQLEFLELPPPQEPLEPS 195 E L+ P P P +P+ Sbjct: 731 EPAPTTPKGTAPTTLKEPAPTTPKKPA 757 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/146 (26%), Positives = 51/146 (34%), Gaps = 7/146 (4%) Query: 59 KEPQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPP 118 KEP P E T P P EP EP + AP P+ AP Sbjct: 479 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 538 Query: 119 ATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNI--EKPQE-APEYQE 175 +E PT + P ++ PK + P P + P++ AP E Sbjct: 539 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTTPE 597 Query: 176 TAAQLEFLELPP--PQEPLEPSNAQE 199 A EL P P+EP P+ +E Sbjct: 598 KPAPTTPEELAPTTPEEP-TPTTPEE 622 Score = 40.4 bits (93), Expect = 0.004 Identities = 37/143 (25%), Positives = 51/143 (35%), Gaps = 13/143 (9%) Query: 55 SSEAKEPQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPES 114 S+ KEP P E T P P EP EP AP P+ Sbjct: 319 STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP--------APTTPKE 370 Query: 115 LAPPATRESQKPPMAHEIPTVLEGQGPANTQD--ATIAQEPKNSEPQDPPNIEKPQEAPE 172 AP T+E P PT + P + T +EP + P++P + AP Sbjct: 371 PAPTTTKE-PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 429 Query: 173 YQETAAQLEFLELPPPQEPLEPS 195 +E A + P P P +P+ Sbjct: 430 TKEPAPTTP--KEPAPTAPKKPA 450 Score = 38.9 bits (89), Expect = 0.010 Identities = 40/144 (27%), Positives = 49/144 (34%), Gaps = 15/144 (10%) Query: 61 PQKL----PEHMNPPAAWE-AQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESL 115 P+KL PE P E A TPE P P EP P + AP P+ Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 647 Query: 116 APPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDP-PNIEKPQEAPEYQ 174 AP +E PT +G P T +EP + P+ P P P E Sbjct: 648 APTTPKEPAPTTPKETAPTTPKGTAP------TTLKEPAPTTPKKPAPKELAPTTTKEPT 701 Query: 175 ETAAQLEFLELP---PPQEPLEPS 195 T P P P EP+ Sbjct: 702 STTCDKPAPTTPKGTAPTTPKEPA 725 Score = 37.7 bits (86), Expect = 0.023 Identities = 38/138 (27%), Positives = 48/138 (34%), Gaps = 17/138 (12%) Query: 59 KEPQKL-PEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAP 117 KEP P+ P E T P P EP P +P AP P+ AP Sbjct: 361 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP--------APTTPKEPAP 412 Query: 118 PATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETA 177 +E PT E PA T +EP + P+ P + AP + Sbjct: 413 TTPKEPTPTTPKEPAPTTKE---PA----PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 465 Query: 178 AQLEFLELPPPQEPLEPS 195 A E P P P EP+ Sbjct: 466 APTTTKE-PSPTTPKEPA 482 Score = 36.2 bits (82), Expect = 0.067 Identities = 32/107 (29%), Positives = 43/107 (40%), Gaps = 15/107 (14%) Query: 76 AQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTV 135 A TP+ P P EP P +P AP PE+ PP T E P E PT Sbjct: 778 APTTPKETAPTTPKEPAPTTPKKP--------APTTPET-PPPTTSEVSTPTTTKE-PTT 827 Query: 136 LEGQGPANTQDATIAQEPK--NSEPQDP--PNIEKPQEA-PEYQETA 177 + +T + + PK + P++P P + P PE TA Sbjct: 828 IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA 874 Score = 35.8 bits (81), Expect = 0.087 Identities = 35/142 (24%), Positives = 48/142 (33%), Gaps = 17/142 (11%) Query: 59 KEPQKLPEHMNPPAAWEAQKTPEFKEPQ----KPPEPQDLLPW---EPPAAWELQEAPAA 111 KEP P + KEP K P P++L P EP + + AP Sbjct: 653 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 712 Query: 112 PESLAPPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAP 171 P+ AP +E PT +G P T +EP + P+ P P+E Sbjct: 713 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAP------TTLKEPAPTTPKKP----APKELA 762 Query: 172 EYQETAAQLEFLELPPPQEPLE 193 + P P P E Sbjct: 763 PTTTKGPTSTTSDKPAPTTPKE 784 Score = 33.5 bits (75), Expect = 0.43 Identities = 34/117 (29%), Positives = 45/117 (38%), Gaps = 16/117 (13%) Query: 59 KEPQKLPEHMNPPAAWEAQKTPEFKEPQ----KPPEPQDLLPWE---PPAAWELQEAPAA 111 KEP P + KEP K P P++L P P + + AP Sbjct: 722 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 781 Query: 112 PESLAP-----PATRESQKP-PMAHEI--PTVLEGQGPANTQD-ATIAQEPKNSEPQ 159 P+ AP PA +KP P E PT E P T++ TI + P S P+ Sbjct: 782 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 838 Score = 32.3 bits (72), Expect = 0.96 Identities = 31/117 (26%), Positives = 43/117 (36%), Gaps = 15/117 (12%) Query: 79 TPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTVLEG 138 TPE P P +P P E + P PE A P T ++ P E Sbjct: 587 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA-PTTPKAAAPNTPKE------- 638 Query: 139 QGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLEPS 195 PA T +EP + P++P + AP + A E P P P +P+ Sbjct: 639 --PA----PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE-PAPTTPKKPA 688 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 47.8 bits (112), Expect = 2e-05 Identities = 39/146 (26%), Positives = 54/146 (36%), Gaps = 10/146 (6%) Query: 59 KEPQKL-PEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAP 117 KEP P+ P E T + P P EP P +P + AP P+ AP Sbjct: 449 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 508 Query: 118 -------PATRESQKPPMAHEIPTVLEGQGPANTQDA-TIAQEPKNSEPQDPPNIEKPQE 169 P T + P PT + P T+ A T +EP + ++P + Sbjct: 509 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 568 Query: 170 APEYQETAAQLEFLELPPPQEPLEPS 195 AP + A E P P P EP+ Sbjct: 569 APTTPKKPAPTTPKE-PAPTTPKEPA 593 Score = 47.4 bits (111), Expect = 3e-05 Identities = 45/176 (25%), Positives = 64/176 (36%), Gaps = 30/176 (17%) Query: 41 QKSQAAKEYDLLRKSS--EAKEPQKLPEHMNPPAAWE----AQKTPEFKEPQKPPEPQDL 94 +K+ +AKE + K+S + K+ P A A TP+ P P EP Sbjct: 302 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAST 361 Query: 95 LPWEP--------------PAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTVLEGQG 140 P EP PA + AP P+ AP T+E PT + Sbjct: 362 TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA 421 Query: 141 PANTQDA-TIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLEPS 195 P T+ A T +EP + P+ P + AP + P P P EP+ Sbjct: 422 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---------PTPTTPKEPA 468 Score = 45.1 bits (105), Expect = 1e-04 Identities = 34/122 (27%), Positives = 47/122 (38%), Gaps = 3/122 (2%) Query: 76 AQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTV 135 A TP+ P P EP P EP + AP P+ AP +E+ PT Sbjct: 569 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 628 Query: 136 LEGQGPANTQD--ATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLE 193 E P + T +E + P++P + AP + AA E P P P E Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-PAPTTPKE 687 Query: 194 PS 195 P+ Sbjct: 688 PA 689 Score = 43.5 bits (101), Expect = 4e-04 Identities = 39/147 (26%), Positives = 51/147 (34%), Gaps = 17/147 (11%) Query: 65 PEHMNPPAAWE-AQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAP------ 117 PE P E A TP+ P P EP P EP + AP P+ AP Sbjct: 653 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 712 Query: 118 -------PATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDP--PNIEKPQ 168 PA +KP PT + + + T D PK + P P P P+ Sbjct: 713 APTTLKEPAPTTPKKPAPKELAPTTTK-EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 771 Query: 169 EAPEYQETAAQLEFLELPPPQEPLEPS 195 E L+ P P P +P+ Sbjct: 772 EPAPTTPKGTAPTTLKEPAPTTPKKPA 798 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/146 (26%), Positives = 51/146 (34%), Gaps = 7/146 (4%) Query: 59 KEPQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPP 118 KEP P E T P P EP EP + AP P+ AP Sbjct: 520 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 579 Query: 119 ATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNI--EKPQE-APEYQE 175 +E PT + P ++ PK + P P + P++ AP E Sbjct: 580 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTTPE 638 Query: 176 TAAQLEFLELPP--PQEPLEPSNAQE 199 A EL P P+EP P+ +E Sbjct: 639 KPAPTTPEELAPTTPEEP-TPTTPEE 663 Score = 40.4 bits (93), Expect = 0.004 Identities = 37/143 (25%), Positives = 51/143 (35%), Gaps = 13/143 (9%) Query: 55 SSEAKEPQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPES 114 S+ KEP P E T P P EP EP AP P+ Sbjct: 360 STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP--------APTTPKE 411 Query: 115 LAPPATRESQKPPMAHEIPTVLEGQGPANTQD--ATIAQEPKNSEPQDPPNIEKPQEAPE 172 AP T+E P PT + P + T +EP + P++P + AP Sbjct: 412 PAPTTTKE-PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 470 Query: 173 YQETAAQLEFLELPPPQEPLEPS 195 +E A + P P P +P+ Sbjct: 471 TKEPAPTTP--KEPAPTAPKKPA 491 Score = 38.9 bits (89), Expect = 0.010 Identities = 40/144 (27%), Positives = 49/144 (34%), Gaps = 15/144 (10%) Query: 61 PQKL----PEHMNPPAAWE-AQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESL 115 P+KL PE P E A TPE P P EP P + AP P+ Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 688 Query: 116 APPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDP-PNIEKPQEAPEYQ 174 AP +E PT +G P T +EP + P+ P P P E Sbjct: 689 APTTPKEPAPTTPKETAPTTPKGTAP------TTLKEPAPTTPKKPAPKELAPTTTKEPT 742 Query: 175 ETAAQLEFLELP---PPQEPLEPS 195 T P P P EP+ Sbjct: 743 STTCDKPAPTTPKGTAPTTPKEPA 766 Score = 37.7 bits (86), Expect = 0.023 Identities = 38/138 (27%), Positives = 48/138 (34%), Gaps = 17/138 (12%) Query: 59 KEPQKL-PEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAP 117 KEP P+ P E T P P EP P +P AP P+ AP Sbjct: 402 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP--------APTTPKEPAP 453 Query: 118 PATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETA 177 +E PT E PA T +EP + P+ P + AP + Sbjct: 454 TTPKEPTPTTPKEPAPTTKE---PA----PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 506 Query: 178 AQLEFLELPPPQEPLEPS 195 A E P P P EP+ Sbjct: 507 APTTTKE-PSPTTPKEPA 523 Score = 36.2 bits (82), Expect = 0.067 Identities = 32/107 (29%), Positives = 43/107 (40%), Gaps = 15/107 (14%) Query: 76 AQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTV 135 A TP+ P P EP P +P AP PE+ PP T E P E PT Sbjct: 819 APTTPKETAPTTPKEPAPTTPKKP--------APTTPET-PPPTTSEVSTPTTTKE-PTT 868 Query: 136 LEGQGPANTQDATIAQEPK--NSEPQDP--PNIEKPQEA-PEYQETA 177 + +T + + PK + P++P P + P PE TA Sbjct: 869 IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA 915 Score = 35.8 bits (81), Expect = 0.087 Identities = 35/142 (24%), Positives = 48/142 (33%), Gaps = 17/142 (11%) Query: 59 KEPQKLPEHMNPPAAWEAQKTPEFKEPQ----KPPEPQDLLPW---EPPAAWELQEAPAA 111 KEP P + KEP K P P++L P EP + + AP Sbjct: 694 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 753 Query: 112 PESLAPPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAP 171 P+ AP +E PT +G P T +EP + P+ P P+E Sbjct: 754 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAP------TTLKEPAPTTPKKP----APKELA 803 Query: 172 EYQETAAQLEFLELPPPQEPLE 193 + P P P E Sbjct: 804 PTTTKGPTSTTSDKPAPTTPKE 825 Score = 33.5 bits (75), Expect = 0.43 Identities = 34/117 (29%), Positives = 45/117 (38%), Gaps = 16/117 (13%) Query: 59 KEPQKLPEHMNPPAAWEAQKTPEFKEPQ----KPPEPQDLLPWE---PPAAWELQEAPAA 111 KEP P + KEP K P P++L P P + + AP Sbjct: 763 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 822 Query: 112 PESLAP-----PATRESQKP-PMAHEI--PTVLEGQGPANTQD-ATIAQEPKNSEPQ 159 P+ AP PA +KP P E PT E P T++ TI + P S P+ Sbjct: 823 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 879 Score = 32.3 bits (72), Expect = 0.96 Identities = 31/117 (26%), Positives = 43/117 (36%), Gaps = 15/117 (12%) Query: 79 TPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTVLEG 138 TPE P P +P P E + P PE A P T ++ P E Sbjct: 628 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA-PTTPKAAAPNTPKE------- 679 Query: 139 QGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLEPS 195 PA T +EP + P++P + AP + A E P P P +P+ Sbjct: 680 --PA----PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE-PAPTTPKKPA 729 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 47.8 bits (112), Expect = 2e-05 Identities = 42/160 (26%), Positives = 66/160 (41%), Gaps = 15/160 (9%) Query: 38 PELQKSQAAKEYDLLRKSSEAKEPQKLPEHMNP---PAAWEAQKTPEFKEPQKPPEPQDL 94 P+ + + + + L S + +EP P P P E+ +P+ +EP P P+ Sbjct: 790 PQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPE-- 847 Query: 95 LPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPK 154 E + EL++ P +P PP E + P E+P P + + EP Sbjct: 848 ---ESHLSPELEKPPLSPRPEKPP--EEPGQCPAPEELPLF---PPPGEPSLSPLLGEPA 899 Query: 155 NSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQEPLEP 194 SEP +PP P+E P L +PP +PL P Sbjct: 900 LSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPP--DPLPP 937 Score = 43.5 bits (101), Expect = 4e-04 Identities = 42/145 (28%), Positives = 54/145 (37%), Gaps = 14/145 (9%) Query: 55 SSEAKEPQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPES 114 S + KEP L P Q P+ + P P LLP PP +E+P +P Sbjct: 403 SMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMP--LLP--PP-----EESPLSP-- 451 Query: 115 LAPPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQ 174 PP + PP A + E + +A P P PP E P P Sbjct: 452 --PPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPES 509 Query: 175 ETAAQLEFLELPPPQEPLEPSNAQE 199 + LE L PP+E PS A E Sbjct: 510 SPFSPLEESPLSPPEES-PPSPALE 533 Score = 42.4 bits (98), Expect = 0.001 Identities = 44/179 (24%), Positives = 74/179 (41%), Gaps = 13/179 (7%) Query: 1 MVEDLAASYIVLKLENEIRQAQVQWLMEENAALQAQIPELQKSQAAKEYDLLRKSSEAKE 60 M L AS + L +E+ + + + ++ + Q Q P Q+ Q +++ LL A + Sbjct: 3236 MESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQ-PAQQQQQQQQQHSLLSAPGPA-Q 3293 Query: 61 PQKLPEHMNPP--AAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPP 118 LP + P A + Q + ++P PQ L+P +PP A A + LAP Sbjct: 3294 AMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPP-------AHALQQRLAPS 3346 Query: 119 ATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETA 177 S + M G P + ++Q+P + P P KPQ+ Q+ A Sbjct: 3347 MAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPMGTMP--PSMCMKPQQLAMQQQLA 3403 Score = 41.2 bits (95), Expect = 0.002 Identities = 40/168 (23%), Positives = 65/168 (38%), Gaps = 12/168 (7%) Query: 36 QIPELQKSQAAKEYDLLRKSSEAKEPQKLPEHMNPPAAWEAQKT-PEFKEPQKPPEPQDL 94 ++P +A++ +S + P++ P M+PP EA + P F+E P P++ Sbjct: 560 ELPTSPPPEASRLSPPPEESPMSPPPEESP--MSPPP--EASRLFPPFEESPLSPPPEES 615 Query: 95 LPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEI-PTVLEGQGPANTQDATIAQEP 153 PP A L P PP PP + P + + +++ ++ P Sbjct: 616 PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPP 675 Query: 154 KNSEPQDPPNIEKPQEAPEYQETAAQLEFLELPPPQE------PLEPS 195 + S PP + PE T+ E PP E PLE S Sbjct: 676 EESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEES 723 Score = 40.8 bits (94), Expect = 0.003 Identities = 52/207 (25%), Positives = 70/207 (33%), Gaps = 8/207 (3%) Query: 28 EENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPEHMN---PPAAWEAQKTPEFKE 84 +E LQ + L K+ E L +E PE PP PE Sbjct: 407 KEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASR 466 Query: 85 PQKPPE--PQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMA--HEIPTVLEGQG 140 PPE P LP + L+E+P +P P + + P + E P + Sbjct: 467 LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEES 526 Query: 141 PANTQDATIAQEPKNSEPQDPPNIEKP-QEAPEYQETAAQLEFLELPPPQEPLEPSNAQE 199 P + T P + P PP E P PE T+ E L PP E S E Sbjct: 527 PPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPE 586 Query: 200 FLELSAAQESLEGLIVVETSAASEFPQ 226 +S E+ E S S P+ Sbjct: 587 ESPMSPPPEASRLFPPFEESPLSPPPE 613 Score = 40.8 bits (94), Expect = 0.003 Identities = 47/178 (26%), Positives = 63/178 (35%), Gaps = 13/178 (7%) Query: 61 PQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWEL----QEAPAAPE--- 113 P++LP PP A PE PPE + P PP A L +E+P +P Sbjct: 558 PEELPTSP-PPEASRLSPPPEESPMSPPPEESPMSP--PPEASRLFPPFEESPLSPPPEE 614 Query: 114 ---SLAPPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEA 170 S P A+R S P + P E + + ++ P S PP Sbjct: 615 SPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP 674 Query: 171 PEYQETAAQLEFLELPPPQEPLEPSNAQEFLELSAAQESLEGLIVVETSAASEFPQAP 228 PE T+ E L PP E S E S E + +E S P+ P Sbjct: 675 PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEP 732 Score = 38.5 bits (88), Expect = 0.013 Identities = 33/138 (23%), Positives = 50/138 (36%), Gaps = 16/138 (11%) Query: 70 PPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMA 129 PP A + +P F+E P P++L PP A L P PP PP A Sbjct: 539 PPEA--SPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEA 596 Query: 130 HEI-PTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQETAAQ--------- 179 + P E +++ ++ P+ S PP + P P + + Sbjct: 597 SRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPE-DSPMSPPPEESPMSPPPEVSRLSP 655 Query: 180 ---LEFLELPPPQEPLEP 194 + L PP + PL P Sbjct: 656 LPVVSRLSPPPEESPLSP 673 Score = 38.5 bits (88), Expect = 0.013 Identities = 44/175 (25%), Positives = 65/175 (37%), Gaps = 9/175 (5%) Query: 61 PQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLL---PWEPPAAWELQEAPAAP---ES 114 P + ++PP P + P PP L P + P + +++PA+P +S Sbjct: 655 PLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDS 714 Query: 115 LAPPATRESQKPPMAHEIPTVLEGQGP-ANTQDATIAQEPKNSEPQDPPNIEKPQEAPEY 173 L ES P+ E +GP + + P+ EP P E+P +P+ Sbjct: 715 LMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQP 774 Query: 174 QE--TAAQLEFLELPPPQEPLEPSNAQEFLELSAAQESLEGLIVVETSAASEFPQ 226 +E A E L P E S E L LS E V E S P+ Sbjct: 775 EEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPE 829 Score = 36.2 bits (82), Expect = 0.067 Identities = 41/150 (27%), Positives = 57/150 (38%), Gaps = 26/150 (17%) Query: 52 LRKSSEAKEPQKLPEHMNPPAAWEA----QKTPEFKEPQKPPEPQDLLPWEPPAAWELQE 107 L +S + P++ P ++PP +++P + PP P P PP Sbjct: 489 LEESPLSPPPEESP--LSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPP------- 539 Query: 108 APAAPESLAPPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKP 167 A+P L+PP ES P E+PT + +A+ P P PP E P Sbjct: 540 PEASP--LSPP-FEESPLSPPPEELPT-------SPPPEASRLSPPPEESPMSPPPEESP 589 Query: 168 QE-APEYQETAAQLEFLELPPPQE--PLEP 194 PE E L PP E PL P Sbjct: 590 MSPPPEASRLFPPFEESPLSPPPEESPLSP 619 Score = 35.4 bits (80), Expect = 0.11 Identities = 35/155 (22%), Positives = 55/155 (35%), Gaps = 20/155 (12%) Query: 14 LENEIRQAQVQWLMEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPEHMNPPAA 73 LE + WL + +A L P LL++ S A EP + + Sbjct: 4845 LEGKSPDTGPDWLKQFDAVL----PGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSN 4900 Query: 74 WEAQK--TPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHE 131 + ++ P +EP PP P P PP E L T +PP+ Sbjct: 4901 LDVRQLSAPPPEEPSPPPSPLAPSPASPPT-----------EPLVELPTEPLAEPPVPSP 4949 Query: 132 IPTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEK 166 +P P + + A+ P+ E PP ++K Sbjct: 4950 LPL---ASSPESARPKPRARPPEEGEDSRPPRLKK 4981 Score = 34.7 bits (78), Expect = 0.19 Identities = 40/155 (25%), Positives = 54/155 (34%), Gaps = 42/155 (27%) Query: 78 KTPE-FKEPQKPP----EPQD----LLPWEPPAAWELQEAPAAPESL-----------AP 117 KTP+ FK P P EPQ L P EPP A L +P + + P Sbjct: 2322 KTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQP 2381 Query: 118 PATRESQKPP-------MAHEIPTVLEGQGPANTQDATIAQEPKNSEP------------ 158 P T Q PP +P+ + PA+ Q + +Q P P Sbjct: 2382 PLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVT 2441 Query: 159 ---QDPPNIEKPQEAPEYQETAAQLEFLELPPPQE 190 Q P +P P+ ++ A L P P E Sbjct: 2442 PRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPE 2476 Score = 33.9 bits (76), Expect = 0.33 Identities = 37/123 (30%), Positives = 47/123 (38%), Gaps = 8/123 (6%) Query: 88 PPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIPTVLEGQGPANTQDA 147 PPEP D EP A + + P+ + + + P+ E + G A Q Sbjct: 374 PPEPGDTPTDEPDALYVACQGQ--PKGGHVTSMQPKEPGPLQCEAKPL----GKAGVQLE 427 Query: 148 TIAQEPKNSE-PQDPPNIEKP-QEAPEYQETAAQLEFLELPPPQEPLEPSNAQEFLELSA 205 + P N E P PP E P PE T+ E L PP E L S E L LS Sbjct: 428 PQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSR 487 Query: 206 AQE 208 E Sbjct: 488 PLE 490 Score = 29.3 bits (64), Expect = 8.2 Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 6/75 (8%) Query: 374 SHTSPATN-LSDLITQCISLEEKPDPNPLGKSSSAEGDGPES-PPAENQPMQAAINCPHI 431 S SP T L +L T+ ++ P P PL S + P + PP E + + P + Sbjct: 4924 SPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRP----PRL 4979 Query: 432 SEAEWVRWHKGRLCL 446 + + VRW + RL L Sbjct: 4980 KKWKGVRWKRLRLLL 4994 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 47.8 bits (112), Expect = 2e-05 Identities = 60/210 (28%), Positives = 90/210 (42%), Gaps = 46/210 (21%) Query: 15 ENEIRQAQVQWLMEENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPEHMNPPAAW 74 E E+ + + + EE L+ ++ +L+ A E + A P LP + PP Sbjct: 939 EGELEEEEEEEDEEEEEELE-EVEDLEFGTAGGEVE-----EGAPPPPTLPPALPPP--- 989 Query: 75 EAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPA-------TRESQKP- 126 ++P +P+ PEP LL E P E + A AP +LAP A RE + P Sbjct: 990 ---ESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAP-TLAPEALPSQGEVEREGESPA 1045 Query: 127 --PMAHEI--------PTVLEGQGPANTQDATIAQEPKNSEPQDPPNIEKPQEAPEYQE- 175 P E+ PT+LE + T+D + +P P + +E EA QE Sbjct: 1046 AGPPPQELVEEEPSAPPTLLEEE----TEDGSDKVQPPPETPAE-EEMETETEAEALQEK 1100 Query: 176 ----TAAQL-EFLELPP----PQEPLEPSN 196 TAA L +F++ PP P P EP + Sbjct: 1101 EQDDTAAMLADFIDCPPDDEKPPPPTEPDS 1130 Score = 38.9 bits (89), Expect = 0.010 Identities = 45/170 (26%), Positives = 63/170 (37%), Gaps = 17/170 (10%) Query: 61 PQKLPEHMNPPAAWEAQKTPEFKEPQKPPEPQDLLPWEPPAAWELQEAPAAPESLAPPAT 120 P+ LP PP + TP P PP +P A E +E PAAP L PP Sbjct: 792 PEGLPPLPPPPPSGA---TPPPIAPTGPPTASPPVP----AKEEPEELPAAPGPLPPPPP 844 Query: 121 RESQKP-----PMAHEIPTVLEGQG--PANTQDATIAQEPKNSEPQDPPNIEKPQEAPEY 173 P P +P G G PA +D T+ + E ++ E+ +E E Sbjct: 845 PPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEE---EEEEEEEEE 901 Query: 174 QETAAQLEFLELPPPQEPLEPSNAQEFLELSAAQESLEGLIVVETSAASE 223 +E + +F E +E +E E E EG + E E Sbjct: 902 EEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDE 951 Score = 29.6 bits (65), Expect = 6.3 Identities = 49/208 (23%), Positives = 76/208 (36%), Gaps = 29/208 (13%) Query: 28 EENAALQAQIPELQKSQAAKEYDLLRKSSEAKEPQKLPEHMNPPAAWEAQKTPEFKEPQK 87 EE + + E ++ +E D E +E ++ E E ++ E ++ ++ Sbjct: 894 EEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEE 953 Query: 88 PPEPQDLLPWEPPAAWELQEAPAAPESLAPPATRESQKPPMAHEIP-----TVLEGQGPA 142 E +++ E A E A P PPA + PP P +LE + P Sbjct: 954 EEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPG 1013 Query: 143 NTQD------ATIAQEPKNS------EPQDPPNIEKPQEAPEYQETAAQLEFLE------ 184 ++ T+A E S E + P PQE E +E +A LE Sbjct: 1014 TEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVE-EEPSAPPTLLEEETEDG 1072 Query: 185 ----LPPPQEPLEPSNAQEFLELSAAQE 208 PPP+ P E E E A QE Sbjct: 1073 SDKVQPPPETPAEEEMETE-TEAEALQE 1099 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.129 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,633,388 Number of Sequences: 37866 Number of extensions: 1262058 Number of successful extensions: 8367 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 107 Number of HSP's successfully gapped in prelim test: 648 Number of HSP's that attempted gapping in prelim test: 6151 Number of HSP's gapped (non-prelim): 2093 length of query: 475 length of database: 18,247,518 effective HSP length: 106 effective length of query: 369 effective length of database: 14,233,722 effective search space: 5252243418 effective search space used: 5252243418 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.