Search of human proteins with 22749191

Search of human proteins with 22749191

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22749191 tetratricopeptide repeat domain 39B [Homo sapiens]
         (616 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22749191 tetratricopeptide repeat domain 39B [Homo sapiens]       1214   0.0  
gi|221307588 tetratricopeptide repeat domain 39A isoform 1 [Homo...   617   e-177
gi|122937436 tetratricopeptide repeat domain 39A isoform 2 [Homo...   615   e-176
gi|209862743 tetratricopeptide repeat domain 39C isoform 1 [Homo...   199   5e-51
gi|116256462 tetratricopeptide repeat domain 39C isoform 2 [Homo...   181   1e-45
gi|110225358 tetratricopeptide repeat domain 7A [Homo sapiens]         35   0.27 
gi|34304360 nephrocystin 3 [Homo sapiens]                              33   0.77 
gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1 ...    32   1.7  
gi|209976994 adenylate cyclase 10 [Homo sapiens]                       32   1.7  
gi|15147337 ubiquitin protein ligase E3 component n-recognin 5 [...    32   1.7  
gi|239749462 PREDICTED: similar to ubiquitin protein ligase E3 c...    31   2.9  
gi|113420453 PREDICTED: similar to ubiquitin protein ligase E3 c...    31   2.9  
gi|31542980 interferon-induced protein with tetratricopeptide re...    30   6.6  
gi|72534658 interferon-induced protein with tetratricopeptide re...    30   6.6  
gi|5901962 MYST histone acetyltransferase 2 [Homo sapiens]             30   6.6  
gi|118150678 epithelial cell transforming sequence 2 oncogene-li...    30   6.6  
gi|16933537 glomulin [Homo sapiens]                                    30   6.6  
gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]           30   6.6  
gi|15619008 vacuolar protein sorting 13A isoform B [Homo sapiens]      30   8.6  
gi|66346676 vacuolar protein sorting 13A isoform D [Homo sapiens]      30   8.6  
gi|66346674 vacuolar protein sorting 13A isoform A [Homo sapiens]      30   8.6  
gi|66346672 vacuolar protein sorting 13A isoform C [Homo sapiens]      30   8.6  

>gi|22749191 tetratricopeptide repeat domain 39B [Homo sapiens]
          Length = 616

 Score = 1214 bits (3141), Expect = 0.0
 Identities = 616/616 (100%), Positives = 616/616 (100%)

Query: 1   MALLGSRAELEADEDVFEDALETISISSHSDMATSSLHFASCDTQQAPRQRGASTVSSSS 60
           MALLGSRAELEADEDVFEDALETISISSHSDMATSSLHFASCDTQQAPRQRGASTVSSSS
Sbjct: 1   MALLGSRAELEADEDVFEDALETISISSHSDMATSSLHFASCDTQQAPRQRGASTVSSSS 60

Query: 61  STKVDLKSGLEECAVALNLFLSNKFTDALELLRPWAKESMYHALGYSTIVVLQAVLTFEQ 120
           STKVDLKSGLEECAVALNLFLSNKFTDALELLRPWAKESMYHALGYSTIVVLQAVLTFEQ
Sbjct: 61  STKVDLKSGLEECAVALNLFLSNKFTDALELLRPWAKESMYHALGYSTIVVLQAVLTFEQ 120

Query: 121 QDIQNGISAMKDALQTCQKYRKKYTVVESFSSLLSRGSLEQLSEEEMHAEICYAECLLQK 180
           QDIQNGISAMKDALQTCQKYRKKYTVVESFSSLLSRGSLEQLSEEEMHAEICYAECLLQK
Sbjct: 121 QDIQNGISAMKDALQTCQKYRKKYTVVESFSSLLSRGSLEQLSEEEMHAEICYAECLLQK 180

Query: 181 AALTFVQDENMINFIKGGLKIRTSYQIYKECLSILHEIQKNKLQQEFFYEFEGGVKLGSG 240
           AALTFVQDENMINFIKGGLKIRTSYQIYKECLSILHEIQKNKLQQEFFYEFEGGVKLGSG
Sbjct: 181 AALTFVQDENMINFIKGGLKIRTSYQIYKECLSILHEIQKNKLQQEFFYEFEGGVKLGSG 240

Query: 241 AFNLMLSLLPARIIRLLEFIGFSGNRELGLLQLREGASGRSMRSALCCLTILAFHTYISL 300
           AFNLMLSLLPARIIRLLEFIGFSGNRELGLLQLREGASGRSMRSALCCLTILAFHTYISL
Sbjct: 241 AFNLMLSLLPARIIRLLEFIGFSGNRELGLLQLREGASGRSMRSALCCLTILAFHTYISL 300

Query: 301 ILGTGEVNVAEAERLLAPFLQQFPNGSLVLFYHARIELLKGNLEEAQEVFQKCVSVQEEW 360
           ILGTGEVNVAEAERLLAPFLQQFPNGSLVLFYHARIELLKGNLEEAQEVFQKCVSVQEEW
Sbjct: 301 ILGTGEVNVAEAERLLAPFLQQFPNGSLVLFYHARIELLKGNLEEAQEVFQKCVSVQEEW 360

Query: 361 KQFHHLCYWELMWINVFQQNWMQAYYYSDLLCKESKWSKATYVFLKAAILSMLPEEDVVA 420
           KQFHHLCYWELMWINVFQQNWMQAYYYSDLLCKESKWSKATYVFLKAAILSMLPEEDVVA
Sbjct: 361 KQFHHLCYWELMWINVFQQNWMQAYYYSDLLCKESKWSKATYVFLKAAILSMLPEEDVVA 420

Query: 421 TNENVVTLFRQVDSLKQRIAGKSIPTEKFAVRKARRYSASLPAPVKLILPALEMMYVWNG 480
           TNENVVTLFRQVDSLKQRIAGKSIPTEKFAVRKARRYSASLPAPVKLILPALEMMYVWNG
Sbjct: 421 TNENVVTLFRQVDSLKQRIAGKSIPTEKFAVRKARRYSASLPAPVKLILPALEMMYVWNG 480

Query: 481 FSIVSKRKDLSENLLVTVEKAEAALQSQNFNSFSVDDECLVKLLKGCCLKNLQRPLQAEL 540
           FSIVSKRKDLSENLLVTVEKAEAALQSQNFNSFSVDDECLVKLLKGCCLKNLQRPLQAEL
Sbjct: 481 FSIVSKRKDLSENLLVTVEKAEAALQSQNFNSFSVDDECLVKLLKGCCLKNLQRPLQAEL 540

Query: 541 CYNHVVESEKLLKYDHYLVPFTLFELASLYKSQGEIDKAIKFLETARNNYKDYSLESRLH 600
           CYNHVVESEKLLKYDHYLVPFTLFELASLYKSQGEIDKAIKFLETARNNYKDYSLESRLH
Sbjct: 541 CYNHVVESEKLLKYDHYLVPFTLFELASLYKSQGEIDKAIKFLETARNNYKDYSLESRLH 600

Query: 601 FRIQAALHLWRKPSSD 616
           FRIQAALHLWRKPSSD
Sbjct: 601 FRIQAALHLWRKPSSD 616


>gi|221307588 tetratricopeptide repeat domain 39A isoform 1 [Homo
           sapiens]
          Length = 581

 Score =  617 bits (1592), Expect = e-177
 Identities = 300/557 (53%), Positives = 410/557 (73%), Gaps = 4/557 (0%)

Query: 50  QRGASTVSSSSSTKVDLKSGLEECAVALNLFLSNKFTDALELLRPWAKESMYHALGYSTI 109
           +  AS  S   + +  L   L++C  AL+LFL+N+F++AL  L+P  KESMYH+L Y+TI
Sbjct: 8   KEAASGKSDRRTPESSLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATI 67

Query: 110 VVLQAVLTFEQQDIQNGISAMKDALQTCQKYRKKYTVVESFSSLLSRGSLEQLSEEEMHA 169
           + +QA++TF+ QDI    + MK+A   CQ++R+K +V +SFSSL++R +L Q +EEE+HA
Sbjct: 68  LEMQAMMTFDPQDILLAGNMMKEAQMLCQRHRRKSSVTDSFSSLVNRPTLGQFTEEEIHA 127

Query: 170 EICYAECLLQKAALTFVQDENMINFIKGGLKIRTSYQIYKECLSILHEIQKNKLQQEFFY 229
           E+CYAECLLQ+AALTF+QDENM++FIKGG+K+R SYQ YKE  S++   Q  K   E   
Sbjct: 128 EVCYAECLLQRAALTFLQDENMVSFIKGGIKVRNSYQTYKELDSLVQSSQYCK--GENHP 185

Query: 230 EFEGGVKLGSGAFNLMLSLLPARIIRLLEFIGFSGNRELGLLQLREGASGRSMRSALCCL 289
            FEGGVKLG GAFNL LS+LP RI+RLLEF+GFSGN++ GLLQL EGASG S RS LC +
Sbjct: 186 HFEGGVKLGVGAFNLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGASGHSFRSVLCVM 245

Query: 290 TILAFHTYISLILGTGEVNVAEAERLLAPFLQQFPNGSLVLFYHARIELLKGNLEEAQEV 349
            +L +HT+++ +LGTG VN+ EAE+LL P+L ++P G++ LF+  RIE++KGN++ A   
Sbjct: 246 LLLCYHTFLTFVLGTGNVNIEEAEKLLKPYLNRYPKGAIFLFFAGRIEVIKGNIDAAIRR 305

Query: 350 FQKCVSVQEEWKQFHHLCYWELMWINVFQQNWMQAYYYSDLLCKESKWSKATYVFLKAAI 409
           F++C   Q+ WKQFHH+CYWELMW   ++  W  +Y+Y+DLL KE+ WSKATY+++KAA 
Sbjct: 306 FEECCEAQQHWKQFHHMCYWELMWCFTYKGQWKMSYFYADLLSKENCWSKATYIYMKAAY 365

Query: 410 LSMLPEEDVVATNENVVTLFRQVDSLKQRIAGKSIPTEKFAVRKARRYSASLPAPVKLIL 469
           LSM  +ED     ++ V LFR V  LK +IAGKS+PTEKFA+RK+RRY +S   P+ L +
Sbjct: 366 LSMFGKEDHKPFGDDEVELFRAVPGLKLKIAGKSLPTEKFAIRKSRRYFSS--NPISLPV 423

Query: 470 PALEMMYVWNGFSIVSKRKDLSENLLVTVEKAEAALQSQNFNSFSVDDECLVKLLKGCCL 529
           PALEMMY+WNG++++ K+  L++ +L  + KAE  L+    N +SVDDECLVKLLKG CL
Sbjct: 424 PALEMMYIWNGYAVIGKQPKLTDGILEIITKAEEMLEKGPENEYSVDDECLVKLLKGLCL 483

Query: 530 KNLQRPLQAELCYNHVVESEKLLKYDHYLVPFTLFELASLYKSQGEIDKAIKFLETARNN 589
           K L R  +AE  +  +  +EK +KYDHYL+P  L ELA L   Q   ++AIK LE+A+ N
Sbjct: 484 KYLGRVQEAEENFRSISANEKKIKYDHYLIPNALLELALLLMEQDRNEEAIKLLESAKQN 543

Query: 590 YKDYSLESRLHFRIQAA 606
           YK+YS+ESR HFRIQAA
Sbjct: 544 YKNYSMESRTHFRIQAA 560


>gi|122937436 tetratricopeptide repeat domain 39A isoform 2 [Homo
           sapiens]
          Length = 578

 Score =  615 bits (1586), Expect = e-176
 Identities = 297/541 (54%), Positives = 404/541 (74%), Gaps = 4/541 (0%)

Query: 66  LKSGLEECAVALNLFLSNKFTDALELLRPWAKESMYHALGYSTIVVLQAVLTFEQQDIQN 125
           L   L++C  AL+LFL+N+F++AL  L+P  KESMYH+L Y+TI+ +QA++TF+ QDI  
Sbjct: 21  LHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATILEMQAMMTFDPQDILL 80

Query: 126 GISAMKDALQTCQKYRKKYTVVESFSSLLSRGSLEQLSEEEMHAEICYAECLLQKAALTF 185
             + MK+A   CQ++R+K +V +SFSSL++R +L Q +EEE+HAE+CYAECLLQ+AALTF
Sbjct: 81  AGNMMKEAQMLCQRHRRKSSVTDSFSSLVNRPTLGQFTEEEIHAEVCYAECLLQRAALTF 140

Query: 186 VQDENMINFIKGGLKIRTSYQIYKECLSILHEIQKNKLQQEFFYEFEGGVKLGSGAFNLM 245
           +QDENM++FIKGG+K+R SYQ YKE  S++   Q  K   E    FEGGVKLG GAFNL 
Sbjct: 141 LQDENMVSFIKGGIKVRNSYQTYKELDSLVQSSQYCK--GENHPHFEGGVKLGVGAFNLT 198

Query: 246 LSLLPARIIRLLEFIGFSGNRELGLLQLREGASGRSMRSALCCLTILAFHTYISLILGTG 305
           LS+LP RI+RLLEF+GFSGN++ GLLQL EGASG S RS LC + +L +HT+++ +LGTG
Sbjct: 199 LSMLPTRILRLLEFVGFSGNKDYGLLQLEEGASGHSFRSVLCVMLLLCYHTFLTFVLGTG 258

Query: 306 EVNVAEAERLLAPFLQQFPNGSLVLFYHARIELLKGNLEEAQEVFQKCVSVQEEWKQFHH 365
            VN+ EAE+LL P+L ++P G++ LF+  RIE++KGN++ A   F++C   Q+ WKQFHH
Sbjct: 259 NVNIEEAEKLLKPYLNRYPKGAIFLFFAGRIEVIKGNIDAAIRRFEECCEAQQHWKQFHH 318

Query: 366 LCYWELMWINVFQQNWMQAYYYSDLLCKESKWSKATYVFLKAAILSMLPEEDVVATNENV 425
           +CYWELMW   ++  W  +Y+Y+DLL KE+ WSKATY+++KAA LSM  +ED     ++ 
Sbjct: 319 MCYWELMWCFTYKGQWKMSYFYADLLSKENCWSKATYIYMKAAYLSMFGKEDHKPFGDDE 378

Query: 426 VTLFRQVDSLKQRIAGKSIPTEKFAVRKARRYSASLPAPVKLILPALEMMYVWNGFSIVS 485
           V LFR V  LK +IAGKS+PTEKFA+RK+RRY +S   P+ L +PALEMMY+WNG++++ 
Sbjct: 379 VELFRAVPGLKLKIAGKSLPTEKFAIRKSRRYFSS--NPISLPVPALEMMYIWNGYAVIG 436

Query: 486 KRKDLSENLLVTVEKAEAALQSQNFNSFSVDDECLVKLLKGCCLKNLQRPLQAELCYNHV 545
           K+  L++ +L  + KAE  L+    N +SVDDECLVKLLKG CLK L R  +AE  +  +
Sbjct: 437 KQPKLTDGILEIITKAEEMLEKGPENEYSVDDECLVKLLKGLCLKYLGRVQEAEENFRSI 496

Query: 546 VESEKLLKYDHYLVPFTLFELASLYKSQGEIDKAIKFLETARNNYKDYSLESRLHFRIQA 605
             +EK +KYDHYL+P  L ELA L   Q   ++AIK LE+A+ NYK+YS+ESR HFRIQA
Sbjct: 497 SANEKKIKYDHYLIPNALLELALLLMEQDRNEEAIKLLESAKQNYKNYSMESRTHFRIQA 556

Query: 606 A 606
           A
Sbjct: 557 A 557


>gi|209862743 tetratricopeptide repeat domain 39C isoform 1 [Homo
           sapiens]
          Length = 583

 Score =  199 bits (507), Expect = 5e-51
 Identities = 147/598 (24%), Positives = 275/598 (45%), Gaps = 64/598 (10%)

Query: 45  QQAPRQRGASTVSSSSSTKVDLKSGLEECAVALNLFLSNKFTDALELLRPWAKESMYHAL 104
           QQ PR+R      ++++    L+   E     +N+ L+N F ++ +L + +   S   + 
Sbjct: 6   QQRPRRRDDGDSDAAAAAAAPLQDA-ELALAGINMLLNNGFRESDQLFKQYRNHSPLMSF 64

Query: 105 GYSTIVVLQAVLTFEQQDIQNGISAMKDALQTCQKYRKKYTVVESFSSLLSRGSLEQLSE 164
           G S +  L A++TFE++ +Q     +K   + C+   ++  V+E+  + + +    + S 
Sbjct: 65  GASFVSFLNAMMTFEEEKMQLACDDLKTTEKLCES--EEAGVIETIKNKIKKNVDVRKSA 122

Query: 165 EEM----HAEICYAECLLQKAALTFVQDENMINFIKGGLKIRTSYQIYKEC---LSILHE 217
             M      +I  A+C +  A L+FV+ E +  +IKGG  +R +++IY +C   ++ L E
Sbjct: 123 PSMVDRLQRQIIIADCQVYLAVLSFVKQE-LSAYIKGGWILRKAWKIYNKCYLDINALQE 181

Query: 218 IQKNKL--------------------QQEFFYEFEGGVKLGSGAFNLMLSLLPARIIRLL 257
           + + KL                     +E     +G V  G G F+L +S++P  +++++
Sbjct: 182 LYQKKLTEESLTSDAANDNHIVAEGVSEESLNRLKGAVSFGYGLFHLCISMVPPNLLKII 241

Query: 258 EFIGFSGNRELGLLQLREGASGRSMRSALCCLTILAFHT----YISLILGTGEVNVAEAE 313
             +GF G+R  GL  L   +  + M++ L  L +L +HT    + +L     +  + EA+
Sbjct: 242 NLLGFPGDRLQGLSSLMYASESKDMKAPLATLALLWYHTVVRPFFALDGSDNKAGLDEAK 301

Query: 314 RLLAPFLQQFPNGSLVLFYHARIELLKGNLEEAQEVFQKCVSVQEEWKQFHHLCYWELMW 373
            +L      +PN SL +F+  RI+ L+  +  A   F   + +  + ++  H+C +E+ W
Sbjct: 302 EILLKKEAAYPNSSLFMFFKGRIQRLECQINSALTSFHTALELAVDQREIQHVCLYEIGW 361

Query: 374 INVFQQNWMQAYYYSDLLCKESKWSKATYVFLKAAILSMLPEEDVVATNENVVTLFRQVD 433
            ++ + N+  A+   + L  ES+WS+  Y +L A       + D          +F++V 
Sbjct: 362 CSMIELNFKDAFDSFERLKNESRWSQCYYAYLTAVCQGATGDVD------GAQIVFKEVQ 415

Query: 434 SLKQRIAGKSIPTEKFAVRKARRYSASLPAPVKLILPALEMMYVWNGFSIVSKRKDLSEN 493
            L +R   K+   E+F+V+KA R+    P     +L ++E++Y+W      S        
Sbjct: 416 KLFKR---KNNQIEQFSVKKAERFRKQTPTKALCVLASIEVLYLWKALPNCSFPN----- 467

Query: 494 LLVTVEKAEAALQSQNFNSFSVDDECLV---KLLKGCCLKNLQRPLQAELCYNHVVESEK 550
                      LQ  +     VDD  +V    LL G   K L     A   +   V+ E 
Sbjct: 468 -----------LQRMSQACHEVDDSSVVGLKYLLLGAIHKCLGNSEDAVQYFQRAVKDEL 516

Query: 551 LLKYDHYLVPFTLFELASLYKSQGE-IDKAIKFLETARNNYKDYSLESRLHFRIQAAL 607
             + + Y+ P+  +EL  L   + E + +    L  A+ ++  Y  E+RLH RI AAL
Sbjct: 517 CRQNNLYVQPYACYELGCLLLDKPETVGRGRALLLQAKEDFSGYDFENRLHVRIHAAL 574


>gi|116256462 tetratricopeptide repeat domain 39C isoform 2 [Homo
           sapiens]
          Length = 522

 Score =  181 bits (460), Expect = 1e-45
 Identities = 134/540 (24%), Positives = 248/540 (45%), Gaps = 63/540 (11%)

Query: 103 ALGYSTIVVLQAVLTFEQQDIQNGISAMKDALQTCQKYRKKYTVVESFSSLLSRGSLEQL 162
           + G S +  L A++TFE++ +Q     +K   + C+   ++  V+E+  + + +    + 
Sbjct: 2   SFGASFVSFLNAMMTFEEEKMQLACDDLKTTEKLCES--EEAGVIETIKNKIKKNVDVRK 59

Query: 163 SEEEM----HAEICYAECLLQKAALTFVQDENMINFIKGGLKIRTSYQIYKEC---LSIL 215
           S   M      +I  A+C +  A L+FV+ E +  +IKGG  +R +++IY +C   ++ L
Sbjct: 60  SAPSMVDRLQRQIIIADCQVYLAVLSFVKQE-LSAYIKGGWILRKAWKIYNKCYLDINAL 118

Query: 216 HEIQKNKL--------------------QQEFFYEFEGGVKLGSGAFNLMLSLLPARIIR 255
            E+ + KL                     +E     +G V  G G F+L +S++P  +++
Sbjct: 119 QELYQKKLTEESLTSDAANDNHIVAEGVSEESLNRLKGAVSFGYGLFHLCISMVPPNLLK 178

Query: 256 LLEFIGFSGNRELGLLQLREGASGRSMRSALCCLTILAFHT----YISLILGTGEVNVAE 311
           ++  +GF G+R  GL  L   +  + M++ L  L +L +HT    + +L     +  + E
Sbjct: 179 IINLLGFPGDRLQGLSSLMYASESKDMKAPLATLALLWYHTVVRPFFALDGSDNKAGLDE 238

Query: 312 AERLLAPFLQQFPNGSLVLFYHARIELLKGNLEEAQEVFQKCVSVQEEWKQFHHLCYWEL 371
           A+ +L      +PN SL +F+  RI+ L+  +  A   F   + +  + ++  H+C +E+
Sbjct: 239 AKEILLKKEAAYPNSSLFMFFKGRIQRLECQINSALTSFHTALELAVDQREIQHVCLYEI 298

Query: 372 MWINVFQQNWMQAYYYSDLLCKESKWSKATYVFLKAAILSMLPEEDVVATNENVVTLFRQ 431
            W ++ + N+  A+   + L  ES+WS+  Y +L A       + D          +F++
Sbjct: 299 GWCSMIELNFKDAFDSFERLKNESRWSQCYYAYLTAVCQGATGDVD------GAQIVFKE 352

Query: 432 VDSLKQRIAGKSIPTEKFAVRKARRYSASLPAPVKLILPALEMMYVWNGFSIVSKRKDLS 491
           V  L +R   K+   E+F+V+KA R+    P     +L ++E++Y+W      S      
Sbjct: 353 VQKLFKR---KNNQIEQFSVKKAERFRKQTPTKALCVLASIEVLYLWKALPNCSFPN--- 406

Query: 492 ENLLVTVEKAEAALQSQNFNSFSVDDECLV---KLLKGCCLKNLQRPLQAELCYNHVVES 548
                        LQ  +     VDD  +V    LL G   K L     A   +   V+ 
Sbjct: 407 -------------LQRMSQACHEVDDSSVVGLKYLLLGAIHKCLGNSEDAVQYFQRAVKD 453

Query: 549 EKLLKYDHYLVPFTLFELASLYKSQGE-IDKAIKFLETARNNYKDYSLESRLHFRIQAAL 607
           E   + + Y+ P+  +EL  L   + E + +    L  A+ ++  Y  E+RLH RI AAL
Sbjct: 454 ELCRQNNLYVQPYACYELGCLLLDKPETVGRGRALLLQAKEDFSGYDFENRLHVRIHAAL 513


>gi|110225358 tetratricopeptide repeat domain 7A [Homo sapiens]
          Length = 858

 Score = 34.7 bits (78), Expect = 0.27
 Identities = 14/43 (32%), Positives = 27/43 (62%)

Query: 323 FPNGSLVLFYHARIELLKGNLEEAQEVFQKCVSVQEEWKQFHH 365
           FP    VL+   R+  +KGNLEEA++++++ ++V  +  +  H
Sbjct: 741 FPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMH 783


>gi|34304360 nephrocystin 3 [Homo sapiens]
          Length = 1330

 Score = 33.1 bits (74), Expect = 0.77
 Identities = 18/51 (35%), Positives = 28/51 (54%), Gaps = 1/51 (1%)

Query: 537  QAELCYNHVVE-SEKLLKYDHYLVPFTLFELASLYKSQGEIDKAIKFLETA 586
            +AE  Y   ++   + L  DH  + +T+  LA LYK  G++DKA+   E A
Sbjct: 1153 KAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKMGKLDKAVPLYELA 1203


>gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1
           [Homo sapiens]
          Length = 847

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 5/89 (5%)

Query: 54  STVSSSSSTKVDLKSGLEECAVALNLFLSNKFTDALELLRPWAKESMYHALGYSTIVVLQ 113
           S++   S TK D+K  LEEC+   N   + KFT    L+ P  +   YH L     +V  
Sbjct: 290 SSLDYISKTKEDVKLKLEECSKRAN---NGKFTLRDLLVVPMQRVLKYHLLLQE--LVKH 344

Query: 114 AVLTFEQQDIQNGISAMKDALQTCQKYRK 142
                E+ +++  + AMKD  Q   + ++
Sbjct: 345 TTDPTEKANLKLALDAMKDLAQYVNEVKR 373


>gi|209976994 adenylate cyclase 10 [Homo sapiens]
          Length = 1610

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 52/246 (21%), Positives = 92/246 (37%), Gaps = 66/246 (26%)

Query: 205  YQIYKECLSILHEIQKNKLQQEFFYEFEGGVKLGSGA------------------FNLML 246
            Y+ ++ECL  +H+ + N++      +F  G+ LG  +                   N   
Sbjct: 1393 YRTFEECLEFIHQYENNRI-----LKFHSGLLLGLYSSVAIWYARLQEWDNFYKFSNRAK 1447

Query: 247  SLLPARIIRLLEFIGFSGNRELGLLQLREGASGRSMRSALCCLTILAFHTYISLILGTGE 306
            +LLP R + L  + G S   E  +L L++    +S  +                   +GE
Sbjct: 1448 NLLPRRTMTLTYYDGISRYMEGQVLHLQKQIKEQSENAQ-----------------ASGE 1490

Query: 307  VNVAEAERLLAPFLQQFPNGSLVL--FYH--ARIELLKGNLEEAQEVFQKCVSVQEEWKQ 362
              +   E L+A    Q   G +     YH  A + +L G+ ++        + + E    
Sbjct: 1491 ELLKNLENLVA----QNTTGPVFCPRLYHLMAYVCILMGDGQKCGLFLNTALRLSETQGN 1546

Query: 363  FHHLCYWELMWINVFQQNWMQAYYYSDLLCKESKWSKATYVFLKAAILSMLPEEDVVATN 422
                C     W+N+ +++W     YS    KE +W +         ILS+   E +VA  
Sbjct: 1547 ILEKC-----WLNMNKESW-----YSTSELKEDQWLQ--------TILSLPSWEKIVAGR 1588

Query: 423  ENVVTL 428
             N+  L
Sbjct: 1589 VNIQDL 1594


>gi|15147337 ubiquitin protein ligase E3 component n-recognin 5 [Homo
            sapiens]
          Length = 2799

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 18/62 (29%), Positives = 31/62 (50%)

Query: 9    ELEADEDVFEDALETISISSHSDMATSSLHFASCDTQQAPRQRGASTVSSSSSTKVDLKS 68
            ++E +  + ++ LE  + SSH++ A  +        +    QR AST  SS+ST     +
Sbjct: 1683 DIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAASSA 1742

Query: 69   GL 70
            GL
Sbjct: 1743 GL 1744


>gi|239749462 PREDICTED: similar to ubiquitin protein ligase E3
            component n-recognin 5 isoform 2 [Homo sapiens]
          Length = 2277

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 18/62 (29%), Positives = 31/62 (50%)

Query: 9    ELEADEDVFEDALETISISSHSDMATSSLHFASCDTQQAPRQRGASTVSSSSSTKVDLKS 68
            ++E +  + ++ LE  + SSH++ A  +        +    QR AST  SS+ST     +
Sbjct: 1162 DIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTLHQRAASTAPSSTSTPAASSA 1221

Query: 69   GL 70
            GL
Sbjct: 1222 GL 1223


>gi|113420453 PREDICTED: similar to ubiquitin protein ligase E3
            component n-recognin 5 isoform 1 [Homo sapiens]
          Length = 2796

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 18/62 (29%), Positives = 31/62 (50%)

Query: 9    ELEADEDVFEDALETISISSHSDMATSSLHFASCDTQQAPRQRGASTVSSSSSTKVDLKS 68
            ++E +  + ++ LE  + SSH++ A  +        +    QR AST  SS+ST     +
Sbjct: 1681 DIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTLHQRAASTAPSSTSTPAASSA 1740

Query: 69   GL 70
            GL
Sbjct: 1741 GL 1742


>gi|31542980 interferon-induced protein with tetratricopeptide
           repeats 3 [Homo sapiens]
          Length = 490

 Score = 30.0 bits (66), Expect = 6.6
 Identities = 31/135 (22%), Positives = 56/135 (41%), Gaps = 18/135 (13%)

Query: 468 ILPALEMMYVWNGFSIVSKRKDLSENLLVTVEKAEAALQSQNFNSFSVDDECLVKLLKGC 527
           ILP L+  + WN F   S  +DL + +   +E      ++  +N  +      +K L G 
Sbjct: 12  ILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLA-----YIKHLDGN 66

Query: 528 ------CLKNLQRPLQAELCYNHVVESEKLLKYDHYLVPFTLFELASLYKSQGEIDKAIK 581
                 CL+  +  +Q E  +    E   L+ + +Y   +  + L  L  +Q  +DK   
Sbjct: 67  NEAALECLRQAEELIQQE--HADQAEIRSLVTWGNY--AWVYYHLGRLSDAQIYVDKV-- 120

Query: 582 FLETARNNYKDYSLE 596
             +T +     YS+E
Sbjct: 121 -KQTCKKFSNPYSIE 134


>gi|72534658 interferon-induced protein with tetratricopeptide
           repeats 3 [Homo sapiens]
          Length = 490

 Score = 30.0 bits (66), Expect = 6.6
 Identities = 31/135 (22%), Positives = 56/135 (41%), Gaps = 18/135 (13%)

Query: 468 ILPALEMMYVWNGFSIVSKRKDLSENLLVTVEKAEAALQSQNFNSFSVDDECLVKLLKGC 527
           ILP L+  + WN F   S  +DL + +   +E      ++  +N  +      +K L G 
Sbjct: 12  ILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLA-----YIKHLDGN 66

Query: 528 ------CLKNLQRPLQAELCYNHVVESEKLLKYDHYLVPFTLFELASLYKSQGEIDKAIK 581
                 CL+  +  +Q E  +    E   L+ + +Y   +  + L  L  +Q  +DK   
Sbjct: 67  NEAALECLRQAEELIQQE--HADQAEIRSLVTWGNY--AWVYYHLGRLSDAQIYVDKV-- 120

Query: 582 FLETARNNYKDYSLE 596
             +T +     YS+E
Sbjct: 121 -KQTCKKFSNPYSIE 134


>gi|5901962 MYST histone acetyltransferase 2 [Homo sapiens]
          Length = 611

 Score = 30.0 bits (66), Expect = 6.6
 Identities = 14/54 (25%), Positives = 29/54 (53%)

Query: 447 EKFAVRKARRYSASLPAPVKLILPALEMMYVWNGFSIVSKRKDLSENLLVTVEK 500
           ++ ++++  + +A  P  +   L AL+M+  W G  +V KR+DL +  +    K
Sbjct: 537 KEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAK 590


>gi|118150678 epithelial cell transforming sequence 2 oncogene-like
           [Homo sapiens]
          Length = 904

 Score = 30.0 bits (66), Expect = 6.6
 Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 5/72 (6%)

Query: 469 LPALEMMY--VWNGF-SIVSKRKDLSENLLVTVEKAEAALQSQNFNSFSVDDECLVKLLK 525
           +PA EM+   V  G  S+V +     E+LL  +EKA    ++Q+   FS  D   + LL+
Sbjct: 297 IPAYEMVMESVKAGVVSVVYEHSVTLESLLYLIEKALDGQKAQSIGIFSDGDSREINLLQ 356

Query: 526 G--CCLKNLQRP 535
           G    +KNL RP
Sbjct: 357 GYKIGVKNLLRP 368


>gi|16933537 glomulin [Homo sapiens]
          Length = 594

 Score = 30.0 bits (66), Expect = 6.6
 Identities = 18/59 (30%), Positives = 30/59 (50%)

Query: 482 SIVSKRKDLSENLLVTVEKAEAALQSQNFNSFSVDDECLVKLLKGCCLKNLQRPLQAEL 540
           S++SK  +L EN L+ +E      Q     SF    + LVK++  C ++ L++   A L
Sbjct: 330 SVISKGLELLENSLLRIEDNSLLYQYLEIKSFLTVPQGLVKVMTLCPIETLRKKSLAML 388


>gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]
          Length = 1564

 Score = 30.0 bits (66), Expect = 6.6
 Identities = 16/62 (25%), Positives = 31/62 (50%), Gaps = 3/62 (4%)

Query: 311 EAERLLAPFLQQFPNGSLVLFYHARIELLKGNLEEAQEVFQKCVSVQEEWKQFHH---LC 367
           EA +++   L  +P+ + V    A I   K +  +A++ FQ+ +    E  ++H+   L 
Sbjct: 404 EAAKIMEDLLSSYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLT 463

Query: 368 YW 369
           YW
Sbjct: 464 YW 465


>gi|15619008 vacuolar protein sorting 13A isoform B [Homo sapiens]
          Length = 3095

 Score = 29.6 bits (65), Expect = 8.6
 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 2/67 (2%)

Query: 90  ELLRPWAKESMYHALGYSTIVVLQAVL-TFEQQDIQNGISAMKDAL-QTCQKYRKKYTVV 147
           E+L P  K  +Y A+GYS   V   +L TFE       + +M   L +  QK      V+
Sbjct: 456 EMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVI 515

Query: 148 ESFSSLL 154
           E FS+L+
Sbjct: 516 EEFSTLI 522


>gi|66346676 vacuolar protein sorting 13A isoform D [Homo sapiens]
          Length = 3069

 Score = 29.6 bits (65), Expect = 8.6
 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 2/67 (2%)

Query: 90  ELLRPWAKESMYHALGYSTIVVLQAVL-TFEQQDIQNGISAMKDAL-QTCQKYRKKYTVV 147
           E+L P  K  +Y A+GYS   V   +L TFE       + +M   L +  QK      V+
Sbjct: 456 EMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVI 515

Query: 148 ESFSSLL 154
           E FS+L+
Sbjct: 516 EEFSTLI 522


>gi|66346674 vacuolar protein sorting 13A isoform A [Homo sapiens]
          Length = 3174

 Score = 29.6 bits (65), Expect = 8.6
 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 2/67 (2%)

Query: 90  ELLRPWAKESMYHALGYSTIVVLQAVL-TFEQQDIQNGISAMKDAL-QTCQKYRKKYTVV 147
           E+L P  K  +Y A+GYS   V   +L TFE       + +M   L +  QK      V+
Sbjct: 456 EMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVI 515

Query: 148 ESFSSLL 154
           E FS+L+
Sbjct: 516 EEFSTLI 522


>gi|66346672 vacuolar protein sorting 13A isoform C [Homo sapiens]
          Length = 3135

 Score = 29.6 bits (65), Expect = 8.6
 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 2/67 (2%)

Query: 90  ELLRPWAKESMYHALGYSTIVVLQAVL-TFEQQDIQNGISAMKDAL-QTCQKYRKKYTVV 147
           E+L P  K  +Y A+GYS   V   +L TFE       + +M   L +  QK      V+
Sbjct: 456 EMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVI 515

Query: 148 ESFSSLL 154
           E FS+L+
Sbjct: 516 EEFSTLI 522


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.133    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,697,927
Number of Sequences: 37866
Number of extensions: 842002
Number of successful extensions: 2381
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2346
Number of HSP's gapped (non-prelim): 31
length of query: 616
length of database: 18,247,518
effective HSP length: 108
effective length of query: 508
effective length of database: 14,157,990
effective search space: 7192258920
effective search space used: 7192258920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.