Search of human proteins with 226693357

Search of human proteins with 226693357

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226693357 phospholipase A2, group IVC isoform 2 precursor
[Homo sapiens]
         (551 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226693357 phospholipase A2, group IVC isoform 2 precursor [Ho...  1127   0.0  
gi|226693354 phospholipase A2, group IVC isoform 1 precursor [Ho...  1079   0.0  
gi|226693363 phospholipase A2, group IVC isoform 3 [Homo sapiens]    1049   0.0  
gi|67972429 phospholipase A2, group IVF [Homo sapiens]                194   1e-49
gi|116174754 phospholipase A2, group IVD [Homo sapiens]               180   3e-45
gi|23943920 cytosolic phospholipase A2, group IVA [Homo sapiens]      167   3e-41
gi|167860120 phospholipase A2, group IVB [Homo sapiens]               165   9e-41
gi|4826914 JMJD7-PLA2G4B protein [Homo sapiens]                       165   9e-41
gi|122937428 phospholipase A2, group 4E [Homo sapiens]                154   2e-37
gi|24308237 phosphatidylinositol transfer protein, membrane-asso...    33   0.89 
gi|254281232 zinc finger and SCAN domain containing 12 [Homo sap...    29   9.8  
gi|50557644 zinc finger, FYVE domain containing 27 isoform b [Ho...    29   9.8  
gi|24497531 Ellis van Creveld syndrome protein [Homo sapiens]          29   9.8  

>gi|226693357 phospholipase A2, group IVC isoform 2 precursor [Homo
           sapiens]
          Length = 551

 Score = 1127 bits (2914), Expect = 0.0
 Identities = 551/551 (100%), Positives = 551/551 (100%)

Query: 1   MRTRPRPRLRRTENFLTAVHHGKKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSG 60
           MRTRPRPRLRRTENFLTAVHHGKKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSG
Sbjct: 1   MRTRPRPRLRRTENFLTAVHHGKKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSG 60

Query: 61  GGLRAHIACLGVLSEMKEQGLLDAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFT 120
           GGLRAHIACLGVLSEMKEQGLLDAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFT
Sbjct: 61  GGLRAHIACLGVLSEMKEQGLLDAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFT 120

Query: 121 RQEWDLAKSLQKTIQAARSENYSLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYP 180
           RQEWDLAKSLQKTIQAARSENYSLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYP
Sbjct: 121 RQEWDLAKSLQKTIQAARSENYSLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYP 180

Query: 181 IFAAIDNDLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPER 240
           IFAAIDNDLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPER
Sbjct: 181 IFAAIDNDLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPER 240

Query: 241 DLTFLRGLWGSALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQES 300
           DLTFLRGLWGSALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQES
Sbjct: 241 DLTFLRGLWGSALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQES 300

Query: 301 SQGEHPPPEDEGGEPEHTWLTEMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGI 360
           SQGEHPPPEDEGGEPEHTWLTEMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGI
Sbjct: 301 SQGEHPPPEDEGGEPEHTWLTEMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGI 360

Query: 361 CASKWEWGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSF 420
           CASKWEWGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSF
Sbjct: 361 CASKWEWGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSF 420

Query: 421 DFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLF 480
           DFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLF
Sbjct: 421 DFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLF 480

Query: 481 NIDACGGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKKKILRELMNVAGLYY 540
           NIDACGGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKKKILRELMNVAGLYY
Sbjct: 481 NIDACGGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKKKILRELMNVAGLYY 540

Query: 541 PKDSARSCCLA 551
           PKDSARSCCLA
Sbjct: 541 PKDSARSCCLA 551


>gi|226693354 phospholipase A2, group IVC isoform 1 precursor [Homo
           sapiens]
          Length = 541

 Score = 1079 bits (2791), Expect = 0.0
 Identities = 528/529 (99%), Positives = 529/529 (100%)

Query: 23  KKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQGLL 82
           +KEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQGLL
Sbjct: 13  QKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQGLL 72

Query: 83  DAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSLQKTIQAARSENY 142
           DAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSLQKTIQAARSENY
Sbjct: 73  DAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSLQKTIQAARSENY 132

Query: 143 SLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQPSWQEARAPETW 202
           SLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQPSWQEARAPETW
Sbjct: 133 SLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQPSWQEARAPETW 192

Query: 203 FEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWGSALGNTEVIREY 262
           FEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWGSALGNTEVIREY
Sbjct: 193 FEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWGSALGNTEVIREY 252

Query: 263 IFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPPPEDEGGEPEHTWLTE 322
           IFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPPPEDEGGEPEHTWLTE
Sbjct: 253 IFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPPPEDEGGEPEHTWLTE 312

Query: 323 MLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWEWGTTHNFLYKHGGIRD 382
           MLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWEWGTTHNFLYKHGGIRD
Sbjct: 313 MLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWEWGTTHNFLYKHGGIRD 372

Query: 383 KIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGDPFETIRATTDYCRRHK 442
           KIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGDPFETIRATTDYCRRHK
Sbjct: 373 KIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGDPFETIRATTDYCRRHK 432

Query: 443 IPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLFNIDACGGDIEAWSDTYDTFKLA 502
           IPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLFNIDACGGDIEAWSDTYDTFKLA
Sbjct: 433 IPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLFNIDACGGDIEAWSDTYDTFKLA 492

Query: 503 DTYTLDVVVLLLALAKKNVRENKKKILRELMNVAGLYYPKDSARSCCLA 551
           DTYTLDVVVLLLALAKKNVRENKKKILRELMNVAGLYYPKDSARSCCLA
Sbjct: 493 DTYTLDVVVLLLALAKKNVRENKKKILRELMNVAGLYYPKDSARSCCLA 541


>gi|226693363 phospholipase A2, group IVC isoform 3 [Homo sapiens]
          Length = 527

 Score = 1049 bits (2712), Expect = 0.0
 Identities = 514/515 (99%), Positives = 515/515 (100%)

Query: 23  KKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQGLL 82
           +KEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQGLL
Sbjct: 13  QKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQGLL 72

Query: 83  DAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSLQKTIQAARSENY 142
           DAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSLQKTIQAARSENY
Sbjct: 73  DAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSLQKTIQAARSENY 132

Query: 143 SLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQPSWQEARAPETW 202
           SLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQPSWQEARAPETW
Sbjct: 133 SLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQPSWQEARAPETW 192

Query: 203 FEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWGSALGNTEVIREY 262
           FEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWGSALGNTEVIREY
Sbjct: 193 FEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWGSALGNTEVIREY 252

Query: 263 IFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPPPEDEGGEPEHTWLTE 322
           IFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPPPEDEGGEPEHTWLTE
Sbjct: 253 IFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPPPEDEGGEPEHTWLTE 312

Query: 323 MLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWEWGTTHNFLYKHGGIRD 382
           MLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWEWGTTHNFLYKHGGIRD
Sbjct: 313 MLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWEWGTTHNFLYKHGGIRD 372

Query: 383 KIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGDPFETIRATTDYCRRHK 442
           KIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGDPFETIRATTDYCRRHK
Sbjct: 373 KIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGDPFETIRATTDYCRRHK 432

Query: 443 IPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLFNIDACGGDIEAWSDTYDTFKLA 502
           IPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLFNIDACGGDIEAWSDTYDTFKLA
Sbjct: 433 IPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLFNIDACGGDIEAWSDTYDTFKLA 492

Query: 503 DTYTLDVVVLLLALAKKNVRENKKKILRELMNVAG 537
           DTYTLDVVVLLLALAKKNVRENKKKILRELMNVAG
Sbjct: 493 DTYTLDVVVLLLALAKKNVRENKKKILRELMNVAG 527


>gi|67972429 phospholipase A2, group IVF [Homo sapiens]
          Length = 849

 Score =  194 bits (494), Expect = 1e-49
 Identities = 154/492 (31%), Positives = 226/492 (45%), Gaps = 84/492 (17%)

Query: 26  EKAAVERRRLHVLKALKKL-----RIEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQG 80
           E+  ++RR+  V KAL+++      +++ + PVVAVLGSGGG RA  +  G L+ ++E G
Sbjct: 324 EQEFLDRRKQVVSKALQQVLGLSEALDSGQVPVVAVLGSGGGTRAMSSLYGSLAGLQELG 383

Query: 81  LLDAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSLQKTIQAARSE 140
           LLD VTYL+GVSGSTW IS+LY    D    +  L+    R +  +  S    +   R +
Sbjct: 384 LLDTVTYLSGVSGSTWCISTLYR---DPAWSQVALQGPIERAQVHVCSSKMGALSTERLQ 440

Query: 141 NY--------------SLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAID 186
            Y              SL D W  +V     +E   + LS+ ++ V +G  PYPI+ +++
Sbjct: 441 YYTQELGVRERSGHSVSLIDLWGLLVEYLLYQEENPAKLSDQQEAVRQGQNPYPIYTSVN 500

Query: 187 NDLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLR 246
                S ++      W EFTP+  GF   GA+V    FGS+   GRL++  PE  + +L+
Sbjct: 501 VRTNLSGEDF---AEWCEFTPYEVGFPKYGAYVPTELFGSELFMGRLLQLQPEPRICYLQ 557

Query: 247 GLWGSALGNTEVIREYIFDQLRNLTLKGL-WRRAVANAKSIGHLIFARLLRLQESSQGEH 305
           G+WGSA   +    + IF +     L  L W R   N                       
Sbjct: 558 GMWGSAFATS---LDEIFLKTAGSGLSFLEWYRGSVNI---------------------- 592

Query: 306 PPPEDEGGEPEHTWLTEMLENWT--RTSLEKQEQPHEDPER---KGSLSNLMDFVKKTGI 360
               D+  +P+       L N +  RT L   + P             ++   F    G+
Sbjct: 593 ---TDDCQKPQ-------LHNPSRLRTRLLTPQGPFSQAVLDIFTSRFTSAQSFNFTRGL 642

Query: 361 CASK--------WEWGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTR 412
           C  K          W  TH   +      +++   R  L+LVD G AIN+PFPL L P R
Sbjct: 643 CLHKDYVAGREFVAWKDTHPDAFP-----NQLTPMRDCLYLVDGGFAINSPFPLALLPQR 697

Query: 413 EVHLILSFDFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYIL---KGE 469
            V LILSFD+S   PFE ++ T  YC    IPFP +E    D+  +    CY+    +  
Sbjct: 698 AVDLILSFDYSLEAPFEVLKMTEKYCLDRGIPFPSIEVGPEDV--EEARECYLFAKAEDP 755

Query: 470 TGPVVMHFPLFN 481
             P+V+HFPL N
Sbjct: 756 RSPIVLHFPLVN 767


>gi|116174754 phospholipase A2, group IVD [Homo sapiens]
          Length = 818

 Score =  180 bits (457), Expect = 3e-45
 Identities = 157/558 (28%), Positives = 244/558 (43%), Gaps = 79/558 (14%)

Query: 18  AVHHGKK---EEKAAVERRRLHVLKALKKLR-----IEADEAPVVAVLGSGGGLRAHIAC 69
           AVH G     EE+A + RR+  V KALK+       ++ DE PVV ++ +GGG RA  + 
Sbjct: 279 AVHLGFNLCAEEQAFLSRRKQVVAKALKQALQLDRDLQEDEVPVVGIMATGGGARAMTSL 338

Query: 70  LGVLSEMKEQGLLDAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKS 129
            G L  +++ GLLD VTY +G+SGSTW ++ LY   GD E  + DL+         LAKS
Sbjct: 339 YGHLLALQKLGLLDCVTYFSGISGSTWTMAHLY---GDPEWSQRDLEGPIRYAREHLAKS 395

Query: 130 LQKTIQAARSENY--------------SLTDFWAYMVISKQTRELPESHLSNMKKPVEEG 175
             +     R  +Y              +  D WA ++ S    ++ +  LS  +  +E G
Sbjct: 396 KLEVFSPERLASYRRELELRAEQGHPTTFVDLWALVLESMLHGQVMDQKLSGQRAALERG 455

Query: 176 TLPYPIFAAIDNDLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVR 235
             P P++ ++  +++ +  E    + W EF+P+  GF   GAFV    FGS+F  GRL+R
Sbjct: 456 QNPLPLYLSL--NVKENNLETLDFKEWVEFSPYEVGFLKYGAFVPPELFGSEFFMGRLMR 513

Query: 236 THPERDLTFLRGLWGSALGNTEVIREYIFDQLRNLTLKG-LWRRAVANAKSIGHLIFARL 294
             PE  + FL  +W      + +    + D   +LT  G  W++ + +            
Sbjct: 514 RIPEPRICFLEAIW------SNIFSLNLLDAWYDLTSSGESWKQHIKDK----------- 556

Query: 295 LRLQESSQGEHPPPEDEGGEPEHTWLT--EMLENWTRTSLEKQEQPHEDPERKGSLSNLM 352
                S + E           E +WL     L    +  L  +      P     L    
Sbjct: 557 ---TRSLEKEPLTTSGTSSRLEASWLQPGTALAQAFKGFLTGRPLHQRSPNFLQGLQLHQ 613

Query: 353 DFVKKTGICASKWEWGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTR 412
           D+      C+ K ++ T  +  Y+   +  ++      L LVDA   INT  P +  P R
Sbjct: 614 DY------CSHK-DFSTWAD--YQLDSMPSQLTPKEPRLCLVDAAYFINTSSPSMFRPGR 664

Query: 413 EVHLILSFDFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKGET-- 470
            + LILSFD+S   PFE ++ T  YCR   +PFP+VE +  D     P  C++       
Sbjct: 665 RLDLILSFDYSLSAPFEALQQTELYCRARGLPFPRVEPSPQD--QHQPRECHLFSDPACP 722

Query: 471 -GPVVMHFPLFN---------------IDACGGDIEAWSDTYDTFKLADTYTLDVVVLLL 514
             P+++HFPL N                +  GG ++    T        TY  +    LL
Sbjct: 723 EAPILLHFPLVNASFKDHSAPGVQRSPAELQGGQVDLTGATCPYTLSNMTYKEEDFERLL 782

Query: 515 ALAKKNVRENKKKILREL 532
            L+  NV+ ++  IL+ L
Sbjct: 783 RLSDYNVQTSQGAILQAL 800


>gi|23943920 cytosolic phospholipase A2, group IVA [Homo sapiens]
          Length = 749

 Score =  167 bits (422), Expect = 3e-41
 Identities = 140/516 (27%), Positives = 237/516 (45%), Gaps = 79/516 (15%)

Query: 25  EEKAAVERRRLHVLKALKKLR--------IEADEAPVVAVLGSGGGLRAHIACLGVLSEM 76
           +EK   ++R+ H+ +++KKL           A + PVVA+LGSGGG RA +   GV+  +
Sbjct: 153 QEKTFRQQRKEHIRESMKKLLGPKNSEGLHSARDVPVVAILGSGGGFRAMVGFSGVMKAL 212

Query: 77  KEQGLLDAVTYLAGVSGSTWAISSLYTN--------DGDMEALEADLKHR----FTRQEW 124
            E G+LD  TY+AG+SGSTW +S+LY++        +   E L  ++ H      T Q+ 
Sbjct: 213 YESGILDCATYVAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKV 272

Query: 125 D-LAKSLQKTIQAARSENYSLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFA 183
               +SL K  + +  +  + TD +  ++          + LS++K+ V     P P+F 
Sbjct: 273 KRYVESLWK--KKSSGQPVTFTDIFGMLIGETLIHNRMNTTLSSLKEKVNTAQCPLPLFT 330

Query: 184 AIDNDLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLT 243
            +   ++P   E    + W EF+P+  G +  G F++   FGSKF  G +V+ + E  L 
Sbjct: 331 CL--HVKPDVSELMFAD-WVEFSPYEIGMAKYGTFMAPDLFGSKFFMGTVVKKYEENPLH 387

Query: 244 FLRGLWGSA----------LGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFAR 293
           FL G+WGSA          +  ++     + ++L N+T K +    V+N  S        
Sbjct: 388 FLMGVWGSAFSILFNRVLGVSGSQSRGSTMEEELENITTKHI----VSNDSSDSD----- 438

Query: 294 LLRLQESSQGEHPPPEDEG----GEPEHTWLTEML------ENWTRTSLEKQEQPHE--- 340
                ES + +    ED G     + + +W+  M+           T   +  + H    
Sbjct: 439 ----DESHEPKGTENEDAGSDYQSDNQASWIHRMIMALVSDSALFNTREGRAGKVHNFML 494

Query: 341 --DPERKGSLSNLMDFVKKTGICASKWEWGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGL 398
             +      LS L DF  +      + +        ++   I + +    K +H+VD+GL
Sbjct: 495 GLNLNTSYPLSPLSDFATQDSFDDDELDAAVADPDEFER--IYEPLDVKSKKIHVVDSGL 552

Query: 399 AINTPFPLVLPPTREVHLILSFDFSA-----GDPFETIRATTDYCRRHKIPFPQVEEAEL 453
             N P+PL+L P R V LI+SFDFSA       PF+ +     + + +K+PFP+++    
Sbjct: 553 TFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMNKLPFPKIDPYVF 612

Query: 454 DLWSKAPASCYILKGETG------PVVMHFPLFNID 483
           D   +    CY+ K +        P ++HF L NI+
Sbjct: 613 D--REGLKECYVFKPKNPDMEKDCPTIIHFVLANIN 646


>gi|167860120 phospholipase A2, group IVB [Homo sapiens]
          Length = 781

 Score =  165 bits (418), Expect = 9e-41
 Identities = 153/550 (27%), Positives = 243/550 (44%), Gaps = 86/550 (15%)

Query: 25  EEKAAVERRRLHVLKALKKLR-----IEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQ 79
           EE+A + RR+  V  AL++       ++ DE PVVA++ +GGG+RA  +  G L+ +KE 
Sbjct: 263 EEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATGGGIRAMTSLYGQLAGLKEL 322

Query: 80  GLLDAVTYLAGVSGSTWAISSLYT----NDGDMEALEADLKHRFTRQEW------DLAKS 129
           GLLD V+Y+ G SGSTWA+++LY     +  D+      LK + T+ +        L + 
Sbjct: 323 GLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLKTQVTKNKLGVLAPSQLQRY 382

Query: 130 LQKTIQAARSENYS-LTDFWAYMVISKQTRELPESH-LSNMKKPVEEGTLPYPIFAAIDN 187
            Q+  + AR    S  T+ WA ++      + P  H LS+ ++ +  G  P PI+ A++ 
Sbjct: 383 RQELAERARLGYPSCFTNLWA-LINEALLHDEPHDHKLSDQREALSHGQNPLPIYCALNT 441

Query: 188 DLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRG 247
             Q S       E W EF+P+  GF   GAF+    FGS+F  G+L++  PE  + FL G
Sbjct: 442 KGQ-SLTTFEFGE-WCEFSPYEVGFPKYGAFIPSELFGSEFFMGQLMKRLPESRICFLEG 499

Query: 248 LWGSALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPP 307
           +W +       +++ ++           W R  AN           LL+++E       P
Sbjct: 500 IWSNLYAAN--LQDSLYWASEPSQFWDRWVRNQANLDKEQ----VPLLKIEE-------P 546

Query: 308 PEDEGGEPEH-----TW--LTEMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGI 360
           P   G   E      TW  L +   N+ R  L   +   + P                  
Sbjct: 547 PSTAGRIAEFFTDLLTWRPLAQATHNFLR-GLHFHKDYFQHPH----------------- 588

Query: 361 CASKWEWGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSF 420
             S W+  T         G+ +++  S  HL L+D G  INT    +L PTR+V LILS 
Sbjct: 589 -FSTWKATTL-------DGLPNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSL 640

Query: 421 DFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKGET---GPVVMHF 477
           D++    F+ ++    +C+   IPFP +  +  +     P  C+     T    P V+HF
Sbjct: 641 DYNLHGAFQQLQLLGRFCQEQGIPFPPISPSPEE--QLQPRECHTFSDPTCPGAPAVLHF 698

Query: 478 PLFN---------------IDACGGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVR 522
           PL +                +A  G++   S          TY+ + V  LL L   NV 
Sbjct: 699 PLVSDSFREYSAPGVRRTPEEAAAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVC 758

Query: 523 ENKKKILREL 532
            N++++L  L
Sbjct: 759 NNQEQLLEAL 768


>gi|4826914 JMJD7-PLA2G4B protein [Homo sapiens]
          Length = 1012

 Score =  165 bits (418), Expect = 9e-41
 Identities = 153/550 (27%), Positives = 243/550 (44%), Gaps = 86/550 (15%)

Query: 25  EEKAAVERRRLHVLKALKKLR-----IEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQ 79
           EE+A + RR+  V  AL++       ++ DE PVVA++ +GGG+RA  +  G L+ +KE 
Sbjct: 494 EEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATGGGIRAMTSLYGQLAGLKEL 553

Query: 80  GLLDAVTYLAGVSGSTWAISSLYT----NDGDMEALEADLKHRFTRQEW------DLAKS 129
           GLLD V+Y+ G SGSTWA+++LY     +  D+      LK + T+ +        L + 
Sbjct: 554 GLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLKTQVTKNKLGVLAPSQLQRY 613

Query: 130 LQKTIQAARSENYS-LTDFWAYMVISKQTRELPESH-LSNMKKPVEEGTLPYPIFAAIDN 187
            Q+  + AR    S  T+ WA ++      + P  H LS+ ++ +  G  P PI+ A++ 
Sbjct: 614 RQELAERARLGYPSCFTNLWA-LINEALLHDEPHDHKLSDQREALSHGQNPLPIYCALNT 672

Query: 188 DLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRG 247
             Q S       E W EF+P+  GF   GAF+    FGS+F  G+L++  PE  + FL G
Sbjct: 673 KGQ-SLTTFEFGE-WCEFSPYEVGFPKYGAFIPSELFGSEFFMGQLMKRLPESRICFLEG 730

Query: 248 LWGSALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPP 307
           +W +       +++ ++           W R  AN           LL+++E       P
Sbjct: 731 IWSNLYAAN--LQDSLYWASEPSQFWDRWVRNQANLDKEQ----VPLLKIEE-------P 777

Query: 308 PEDEGGEPEH-----TW--LTEMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGI 360
           P   G   E      TW  L +   N+ R  L   +   + P                  
Sbjct: 778 PSTAGRIAEFFTDLLTWRPLAQATHNFLR-GLHFHKDYFQHPH----------------- 819

Query: 361 CASKWEWGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSF 420
             S W+  T         G+ +++  S  HL L+D G  INT    +L PTR+V LILS 
Sbjct: 820 -FSTWKATTL-------DGLPNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSL 871

Query: 421 DFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKGET---GPVVMHF 477
           D++    F+ ++    +C+   IPFP +  +  +     P  C+     T    P V+HF
Sbjct: 872 DYNLHGAFQQLQLLGRFCQEQGIPFPPISPSPEE--QLQPRECHTFSDPTCPGAPAVLHF 929

Query: 478 PLFN---------------IDACGGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVR 522
           PL +                +A  G++   S          TY+ + V  LL L   NV 
Sbjct: 930 PLVSDSFREYSAPGVRRTPEEAAAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVC 989

Query: 523 ENKKKILREL 532
            N++++L  L
Sbjct: 990 NNQEQLLEAL 999


>gi|122937428 phospholipase A2, group 4E [Homo sapiens]
          Length = 839

 Score =  154 bits (389), Expect = 2e-37
 Identities = 141/546 (25%), Positives = 237/546 (43%), Gaps = 81/546 (14%)

Query: 30  VERRRLHVLKALKKLR-----IEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQGLLDA 84
           +++R++ V KALK++      ++ DE P++A++ +GGG R+  +  G L  +++  LLD 
Sbjct: 316 LQKRKVVVAKALKQVLQLEEDLQEDEVPLIAIMATGGGTRSMTSMYGHLLGLQKLNLLDC 375

Query: 85  VTYLAGVSGSTWAISSLYTNDGD----------MEALEADLKHRFTRQEWDLAKSLQKTI 134
            +Y+ G+SG+TW +++LY  D D           EA    +K +      D  +  Q+ +
Sbjct: 376 ASYITGLSGATWTMATLY-RDPDWSSKNLEPAIFEARRHVVKDKLPSLFPDQLRKFQEEL 434

Query: 135 QAARSENY--SLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQPS 192
           +    E Y  + TDFW  ++ +    E  E  LS+ +  +  G  P PI+  I+     S
Sbjct: 435 RQRSQEGYRVTFTDFWGLLIETCLGDERNECKLSDQRAALSCGQNPLPIYLTINVKDDVS 494

Query: 193 WQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWGSA 252
            Q+ R    WFEF+P+  G    GAF+    FGS+F  GRLV+  PE  + ++ GLW S 
Sbjct: 495 NQDFR---EWFEFSPYEVGLQKYGAFIPSELFGSEFFMGRLVKRIPESRICYMLGLWSS- 550

Query: 253 LGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHP----PP 308
                         + +L L   W     N        F R  R +     + P     P
Sbjct: 551 --------------IFSLNLLDAW-----NLSHTSEEFFHRWTREKVQDIEDEPILPEIP 591

Query: 309 EDEGGEPEHTWLT--EMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWE 366
           + +    E T +     L N  R  L  +    E       L    ++++      S+W+
Sbjct: 592 KCDANILETTVVIPGSWLSNSFREILTHRSFVSEFHNFLSGLQLHTNYLQNGQF--SRWK 649

Query: 367 WGTTHNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGD 426
                 F        +++  S  HL L+D    +N+ +P +L P R+  LI+  ++ AG 
Sbjct: 650 DTVLDGF-------PNQLTESANHLCLLDTAFFVNSSYPPLLRPERKADLIIHLNYCAGS 702

Query: 427 PFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKG---ETGPVVMHFPLFN-- 481
             + ++ T +YC    IPFP+    EL   ++    CY+++       P+V  FPL N  
Sbjct: 703 QTKPLKQTCEYCTVQNIPFPKY---ELPDENENLKECYLMENPQEPDAPIVTFFPLINDT 759

Query: 482 ---------------IDACGGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKK 526
                          ++    DI      Y T +L  TYT      L+ L++ N+  NK 
Sbjct: 760 FRKYKAPGVERSPEELEQGQVDIYGPKTPYATKEL--TYTEATFDKLVKLSEYNILNNKD 817

Query: 527 KILREL 532
            +L+ L
Sbjct: 818 TLLQAL 823


>gi|24308237 phosphatidylinositol transfer protein,
           membrane-associated 2 [Homo sapiens]
          Length = 1349

 Score = 32.7 bits (73), Expect = 0.89
 Identities = 36/172 (20%), Positives = 63/172 (36%), Gaps = 46/172 (26%)

Query: 297 LQESSQGEHPPPEDEGGEP------EHTWLT----------------EMLENWTRTSLEK 334
           + + + GE P P    GEP      +  W T                  +  W   S+ +
Sbjct: 276 VSDQTSGEPPEPSSSNGEPLVGRGLKKQWSTSSKSSRSSKRGASPSRHSISEWRMQSIAR 335

Query: 335 QEQPHEDPERKGSLSNLMDFVKKTGICASKW------------EWGTTHNFLYKHGGIRD 382
                 D E   +  +L D  +      +KW            E   T + LY+ G    
Sbjct: 336 DSDESSDDEFFDAHEDLSDTEEMFPKDITKWSSNDLMDKIESPEPEDTQDGLYRQGAPEF 395

Query: 383 KIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLIL-------SFDFSAGDP 427
           ++ SS + L++++  ++     PL  PP++ +H++L         D  AGDP
Sbjct: 396 RVASSVEQLNIIEDEVS----QPLAAPPSK-IHVLLLVLHGGTILDTGAGDP 442


>gi|254281232 zinc finger and SCAN domain containing 12 [Homo
           sapiens]
          Length = 611

 Score = 29.3 bits (64), Expect = 9.8
 Identities = 15/36 (41%), Positives = 21/36 (58%), Gaps = 1/36 (2%)

Query: 94  STWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKS 129
           STWAI +    D  +E    + K+  TRQ+WDL K+
Sbjct: 3   STWAIQAHMDQDEPLEVKIEEEKYT-TRQDWDLRKN 37


>gi|50557644 zinc finger, FYVE domain containing 27 isoform b [Homo
           sapiens]
          Length = 411

 Score = 29.3 bits (64), Expect = 9.8
 Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 7/94 (7%)

Query: 298 QESSQGEHPPPEDEGGEP---EHTWLTEMLENWTRTSLEKQEQPHEDPERKGSL--SNLM 352
           QE    E PPP D GG+    + T      E+ T  S+E+ E+   D E K ++  ++L+
Sbjct: 238 QEEHAFESPPPPDVGGKDGLMDSTPALTPTEDLTPGSVEEAEEAEPDEEFKDAIEETHLV 297

Query: 353 DFVKKTGI-CASKWEWGTTHN-FLYKHGGIRDKI 384
                 G  C ++ E     N FL K+  +R K+
Sbjct: 298 VLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKV 331


>gi|24497531 Ellis van Creveld syndrome protein [Homo sapiens]
          Length = 992

 Score = 29.3 bits (64), Expect = 9.8
 Identities = 24/109 (22%), Positives = 43/109 (39%), Gaps = 8/109 (7%)

Query: 231 GRLVRTHPERDLTFLRGLWGSALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLI 290
           GR++  H ER L  L+ L G  + N      Y   + + L+      R    A      +
Sbjct: 798 GRIMEDHEERKLQHLKTLQGERMEN------YKLRKKQELSNPSSGSRTAGGAHETSQAV 851

Query: 291 FARLLRLQESSQGEHPPPEDE--GGEPEHTWLTEMLENWTRTSLEKQEQ 337
             R+L  Q+    + P  +      + +   + ++LE    T L++ EQ
Sbjct: 852 HQRMLSQQKRFLAQFPVHQQMRLHAQQQQAGVMDLLEAQLETQLQEAEQ 900


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,547,657
Number of Sequences: 37866
Number of extensions: 1050650
Number of successful extensions: 2743
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2701
Number of HSP's gapped (non-prelim): 21
length of query: 551
length of database: 18,247,518
effective HSP length: 107
effective length of query: 444
effective length of database: 14,195,856
effective search space: 6302960064
effective search space used: 6302960064
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.