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Search of human proteins with 225735595
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|225735595 RNA polymerase II associated protein 3 isoform 3
[Homo sapiens]
(506 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 993 0.0
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 993 0.0
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 903 0.0
gi|21361356 translocase of outer mitochondrial membrane 34 [Homo... 103 4e-22
gi|27262638 sperm associated antigen 1 [Homo sapiens] 99 7e-21
gi|27262636 sperm associated antigen 1 [Homo sapiens] 99 7e-21
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 89 1e-17
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 82 1e-15
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 82 1e-15
gi|4503729 FK506 binding protein 52 [Homo sapiens] 77 4e-14
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 76 6e-14
gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] 76 8e-14
gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] 76 8e-14
gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] 76 8e-14
gi|54607135 translocase of outer mitochondrial membrane 70 homol... 75 1e-13
gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 71 3e-12
gi|89179321 smooth muscle cell associated protein-1 isoform 3 [H... 71 3e-12
gi|29725607 smooth muscle cell associated protein-1 isoform 2 [H... 71 3e-12
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 70 3e-12
gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens] 70 6e-12
gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens] 68 2e-11
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 67 4e-11
gi|17149853 WAF-1/CIP1 stabilizing protein 39 [Homo sapiens] 62 1e-09
gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens] 61 2e-09
gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens] 61 2e-09
gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Hom... 59 1e-08
gi|56181387 STIP1 homology and U-box containing protein 1 [Homo ... 59 1e-08
gi|19923193 heat shock 70kD protein binding protein [Homo sapiens] 54 3e-07
gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sap... 54 4e-07
gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 52 2e-06
>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 993 bits (2568), Expect = 0.0
Identities = 506/506 (100%), Positives = 506/506 (100%)
Query: 1 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 60
MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE
Sbjct: 1 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 60
Query: 61 AKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK 120
AKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK
Sbjct: 61 AKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK 120
Query: 121 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC 180
QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC
Sbjct: 121 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC 180
Query: 181 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 240
TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE
Sbjct: 181 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 240
Query: 241 KGHWDDVFLDSTQRQNVVKPIDNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPE 300
KGHWDDVFLDSTQRQNVVKPIDNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPE
Sbjct: 241 KGHWDDVFLDSTQRQNVVKPIDNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPE 300
Query: 301 NNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVC 360
NNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVC
Sbjct: 301 NNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVC 360
Query: 361 QSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYP 420
QSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYP
Sbjct: 361 QSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYP 420
Query: 421 KLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIA 480
KLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIA
Sbjct: 421 KLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIA 480
Query: 481 RALFNHIDKSGLKDSSVEELKKRYGG 506
RALFNHIDKSGLKDSSVEELKKRYGG
Sbjct: 481 RALFNHIDKSGLKDSSVEELKKRYGG 506
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 993 bits (2568), Expect = 0.0
Identities = 506/506 (100%), Positives = 506/506 (100%)
Query: 1 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 60
MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE
Sbjct: 160 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 219
Query: 61 AKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK 120
AKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK
Sbjct: 220 AKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK 279
Query: 121 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC 180
QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC
Sbjct: 280 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC 339
Query: 181 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 240
TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE
Sbjct: 340 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 399
Query: 241 KGHWDDVFLDSTQRQNVVKPIDNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPE 300
KGHWDDVFLDSTQRQNVVKPIDNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPE
Sbjct: 400 KGHWDDVFLDSTQRQNVVKPIDNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPE 459
Query: 301 NNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVC 360
NNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVC
Sbjct: 460 NNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVC 519
Query: 361 QSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYP 420
QSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYP
Sbjct: 520 QSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYP 579
Query: 421 KLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIA 480
KLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIA
Sbjct: 580 KLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIA 639
Query: 481 RALFNHIDKSGLKDSSVEELKKRYGG 506
RALFNHIDKSGLKDSSVEELKKRYGG
Sbjct: 640 RALFNHIDKSGLKDSSVEELKKRYGG 665
Score = 134 bits (337), Expect = 2e-31
Identities = 66/136 (48%), Positives = 93/136 (68%)
Query: 106 STEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAM 165
S E E ++ + Q+A+ K++GN +FK+GKY+ AI+CYT+G+ AD N +LP NRA
Sbjct: 116 SQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRAS 175
Query: 166 AYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNK 225
AY +++K+ AE DC A+ L+ SY+KA++RRG AR L KL EAK+D+E VL LEP N
Sbjct: 176 AYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNF 235
Query: 226 QAVTELSKIKKELIEK 241
+A EL KI + L K
Sbjct: 236 EATNELRKISQALASK 251
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 903 bits (2333), Expect = 0.0
Identities = 472/506 (93%), Positives = 472/506 (93%), Gaps = 34/506 (6%)
Query: 1 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 60
MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE
Sbjct: 160 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 219
Query: 61 AKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK 120
AKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK
Sbjct: 220 AKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK 279
Query: 121 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC 180
QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC
Sbjct: 280 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC 339
Query: 181 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 240
TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK
Sbjct: 340 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK---- 395
Query: 241 KGHWDDVFLDSTQRQNVVKPIDNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPE 300
KPLKKVIIEETGNLIQTIDVPDSTTAAAPE
Sbjct: 396 ------------------------------KPLKKVIIEETGNLIQTIDVPDSTTAAAPE 425
Query: 301 NNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVC 360
NNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVC
Sbjct: 426 NNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVC 485
Query: 361 QSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYP 420
QSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYP
Sbjct: 486 QSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYP 545
Query: 421 KLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIA 480
KLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIA
Sbjct: 546 KLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIA 605
Query: 481 RALFNHIDKSGLKDSSVEELKKRYGG 506
RALFNHIDKSGLKDSSVEELKKRYGG
Sbjct: 606 RALFNHIDKSGLKDSSVEELKKRYGG 631
Score = 134 bits (337), Expect = 2e-31
Identities = 66/136 (48%), Positives = 93/136 (68%)
Query: 106 STEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAM 165
S E E ++ + Q+A+ K++GN +FK+GKY+ AI+CYT+G+ AD N +LP NRA
Sbjct: 116 SQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRAS 175
Query: 166 AYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNK 225
AY +++K+ AE DC A+ L+ SY+KA++RRG AR L KL EAK+D+E VL LEP N
Sbjct: 176 AYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNF 235
Query: 226 QAVTELSKIKKELIEK 241
+A EL KI + L K
Sbjct: 236 EATNELRKISQALASK 251
>gi|21361356 translocase of outer mitochondrial membrane 34 [Homo
sapiens]
Length = 309
Score = 103 bits (257), Expect = 4e-22
Identities = 74/257 (28%), Positives = 119/257 (46%), Gaps = 27/257 (10%)
Query: 9 VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERV 68
VL +NRA+ + + DC A+AL K RR +A AL+K A DY+ V
Sbjct: 52 VLYSNRAACHLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTV 111
Query: 69 LELEPNNFEATNELRKISQALAS----------------------KENSYPKE-----AD 101
L+++ N A + ++++AL + NS P E A
Sbjct: 112 LQIDDNVTSAVEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAK 171
Query: 102 IVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPA 161
K T + ++ + + ++A K+ GN K+G +++AIE Y+ + + +
Sbjct: 172 SKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYS 231
Query: 162 NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLE 221
NRA+ YL +++Y EA KDCT+A+ LDG KAF RR A L + D +L +E
Sbjct: 232 NRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIE 291
Query: 222 PGNKQAVTELSKIKKEL 238
P N A ++K+ L
Sbjct: 292 PRNGPAQKLRQEVKQNL 308
Score = 50.4 bits (119), Expect = 4e-06
Identities = 36/119 (30%), Positives = 59/119 (49%), Gaps = 8/119 (6%)
Query: 130 GNGFFKEGKYERAIECYTRGIA---ADGAN-----ALLPANRAMAYLKIQKYEEAEKDCT 181
GN F+ G+Y A Y R + A G++ ++L +NRA +LK + KDCT
Sbjct: 16 GNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCT 75
Query: 182 QAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 240
A+ L K RR +A L K A D++TVL ++ AV ++++ + L++
Sbjct: 76 SALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRALMD 134
>gi|27262638 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 99.4 bits (246), Expect = 7e-21
Identities = 93/378 (24%), Positives = 165/378 (43%), Gaps = 27/378 (7%)
Query: 9 VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERV 68
+L +NRA+ Y + + DCN A+ L+ K RR A L++ +A DY+ V
Sbjct: 488 ILYSNRAACYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTV 547
Query: 69 LELEPNNFEATNELRKISQALASKENSYPKE---------ADIVIKSTEGERKQIEAQ-- 117
L+++ A + + ++S+ L + +E A + +++ ++ I Q
Sbjct: 548 LQIDCGLQLANDSVNRLSRILMELDGPNWREKLSPIPAVPASVPLQAWHPAKEMISKQAG 607
Query: 118 ---QNKQQAISE-------KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAY 167
++QQ I++ K+ GN + Y+ A+ Y+ + + + NRA+ Y
Sbjct: 608 DSSSHRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYTNRALCY 667
Query: 168 LKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQA 227
LK+ ++EEA++DC QA+ L KAF RR A L ++ D V+LL+P +A
Sbjct: 668 LKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLDPSIIEA 727
Query: 228 VTELSKIKKELIEKGHWDDVFLDSTQR----QNVVKPIDNPPHPGSTKPLKKVIIEETGN 283
EL ++ + L K + +R Q V + + P P + + E+ G
Sbjct: 728 KMELEEVTRLLNLKDKTAPFNKEKERRKIEIQEVNEGKEEPGRPAGEVSMGCLASEKGGK 787
Query: 284 LIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEV 343
++ + P+ A P NN +I A T K + L T+ L +
Sbjct: 788 SSRSPEDPEKLPIAKP-NNAYEFGQIINALSTRKDKEACAHLLAITAPKDLPMFLSNKLE 846
Query: 344 SDTSSLQPQASLKQDVCQ 361
DT L Q SLK ++ +
Sbjct: 847 GDTFLLLIQ-SLKNNLIE 863
Score = 76.6 bits (187), Expect = 5e-14
Identities = 52/167 (31%), Positives = 82/167 (49%), Gaps = 3/167 (1%)
Query: 72 EPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGN 131
E + F+ E KI + KE + ++ + T + + ++ A EK++GN
Sbjct: 160 EWDKFDVEKECLKIDEDY--KEKTVIDKSHLSKIETRIDTAGLTEKEKDFLATREKEKGN 217
Query: 132 GFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYS 191
F G YE A+ YTR I+A + NRA A +K+Q + A +DC + + L+
Sbjct: 218 EAFNSGDYEEAVMYYTRSISAL-PTVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNV 276
Query: 192 KAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKEL 238
KA RR T KL EA +D VL +EP N A LS+++++L
Sbjct: 277 KALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERDL 323
Score = 53.1 bits (126), Expect = 6e-07
Identities = 52/208 (25%), Positives = 87/208 (41%), Gaps = 25/208 (12%)
Query: 90 ASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRG 149
A + P+ A + G Q + K +GN F+ G++ A Y+
Sbjct: 412 AGADKRSPRRASAAAAAGGGATGHPGGGQGAENPAGLKSQGNELFRSGQFAEAAGKYSAA 471
Query: 150 IA---------ADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTA 200
IA AD + +L +NRA YLK +DC +A+ L K RR A
Sbjct: 472 IALLEPAGSEIADDLS-ILYSNRAACYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMA 530
Query: 201 RTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQRQNVVKP 260
L + +A D++TVL ++ G + A ++++ + L+E LD + + P
Sbjct: 531 YETLEQYGKAYVDYKTVLQIDCGLQLANDSVNRLSRILME--------LDGPNWREKLSP 582
Query: 261 IDNPPHPGST-----KPLKKVIIEETGN 283
I P P S P K++I ++ G+
Sbjct: 583 I--PAVPASVPLQAWHPAKEMISKQAGD 608
Score = 48.9 bits (115), Expect = 1e-05
Identities = 33/117 (28%), Positives = 54/117 (46%), Gaps = 7/117 (5%)
Query: 13 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 72
NRA A +L+ + A DC + L KA RR KL EA +D +VL++E
Sbjct: 247 NRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVE 306
Query: 73 PNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDR 129
P+N A L ++ + L + E + + T+G+R I+ +N + + R
Sbjct: 307 PDNDLAKKTLSEVERDLKNSEAASETQ-------TKGKRMVIQEIENSEDEEGKSGR 356
Score = 38.1 bits (87), Expect = 0.019
Identities = 41/138 (29%), Positives = 58/138 (42%), Gaps = 23/138 (16%)
Query: 44 AYSRRGAARFALQKLEEAKKDYERVLELEPNNFEA----------TNELRKISQALASKE 93
AY+ R A LQ A +D E+VLELEP N +A N+LR+ ++ L+
Sbjct: 244 AYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVL 303
Query: 94 NSYPKE--ADIVIKSTEGERKQIEA---QQNKQQAISEKDRGNGFFKEGKYERAIECYTR 148
+ P A + E + K EA Q K + + ++ N +EGK R E
Sbjct: 304 DVEPDNDLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEEGKSGRKHE---- 359
Query: 149 GIAADGANALLPANRAMA 166
DG PA A A
Sbjct: 360 ----DGGGDKKPAEPAGA 373
>gi|27262636 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 99.4 bits (246), Expect = 7e-21
Identities = 93/378 (24%), Positives = 165/378 (43%), Gaps = 27/378 (7%)
Query: 9 VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERV 68
+L +NRA+ Y + + DCN A+ L+ K RR A L++ +A DY+ V
Sbjct: 488 ILYSNRAACYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTV 547
Query: 69 LELEPNNFEATNELRKISQALASKENSYPKE---------ADIVIKSTEGERKQIEAQ-- 117
L+++ A + + ++S+ L + +E A + +++ ++ I Q
Sbjct: 548 LQIDCGLQLANDSVNRLSRILMELDGPNWREKLSPIPAVPASVPLQAWHPAKEMISKQAG 607
Query: 118 ---QNKQQAISE-------KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAY 167
++QQ I++ K+ GN + Y+ A+ Y+ + + + NRA+ Y
Sbjct: 608 DSSSHRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYTNRALCY 667
Query: 168 LKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQA 227
LK+ ++EEA++DC QA+ L KAF RR A L ++ D V+LL+P +A
Sbjct: 668 LKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLDPSIIEA 727
Query: 228 VTELSKIKKELIEKGHWDDVFLDSTQR----QNVVKPIDNPPHPGSTKPLKKVIIEETGN 283
EL ++ + L K + +R Q V + + P P + + E+ G
Sbjct: 728 KMELEEVTRLLNLKDKTAPFNKEKERRKIEIQEVNEGKEEPGRPAGEVSMGCLASEKGGK 787
Query: 284 LIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEV 343
++ + P+ A P NN +I A T K + L T+ L +
Sbjct: 788 SSRSPEDPEKLPIAKP-NNAYEFGQIINALSTRKDKEACAHLLAITAPKDLPMFLSNKLE 846
Query: 344 SDTSSLQPQASLKQDVCQ 361
DT L Q SLK ++ +
Sbjct: 847 GDTFLLLIQ-SLKNNLIE 863
Score = 76.6 bits (187), Expect = 5e-14
Identities = 52/167 (31%), Positives = 82/167 (49%), Gaps = 3/167 (1%)
Query: 72 EPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGN 131
E + F+ E KI + KE + ++ + T + + ++ A EK++GN
Sbjct: 160 EWDKFDVEKECLKIDEDY--KEKTVIDKSHLSKIETRIDTAGLTEKEKDFLATREKEKGN 217
Query: 132 GFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYS 191
F G YE A+ YTR I+A + NRA A +K+Q + A +DC + + L+
Sbjct: 218 EAFNSGDYEEAVMYYTRSISAL-PTVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNV 276
Query: 192 KAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKEL 238
KA RR T KL EA +D VL +EP N A LS+++++L
Sbjct: 277 KALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERDL 323
Score = 53.1 bits (126), Expect = 6e-07
Identities = 52/208 (25%), Positives = 87/208 (41%), Gaps = 25/208 (12%)
Query: 90 ASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRG 149
A + P+ A + G Q + K +GN F+ G++ A Y+
Sbjct: 412 AGADKRSPRRASAAAAAGGGATGHPGGGQGAENPAGLKSQGNELFRSGQFAEAAGKYSAA 471
Query: 150 IA---------ADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTA 200
IA AD + +L +NRA YLK +DC +A+ L K RR A
Sbjct: 472 IALLEPAGSEIADDLS-ILYSNRAACYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMA 530
Query: 201 RTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQRQNVVKP 260
L + +A D++TVL ++ G + A ++++ + L+E LD + + P
Sbjct: 531 YETLEQYGKAYVDYKTVLQIDCGLQLANDSVNRLSRILME--------LDGPNWREKLSP 582
Query: 261 IDNPPHPGST-----KPLKKVIIEETGN 283
I P P S P K++I ++ G+
Sbjct: 583 I--PAVPASVPLQAWHPAKEMISKQAGD 608
Score = 48.9 bits (115), Expect = 1e-05
Identities = 33/117 (28%), Positives = 54/117 (46%), Gaps = 7/117 (5%)
Query: 13 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 72
NRA A +L+ + A DC + L KA RR KL EA +D +VL++E
Sbjct: 247 NRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVE 306
Query: 73 PNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDR 129
P+N A L ++ + L + E + + T+G+R I+ +N + + R
Sbjct: 307 PDNDLAKKTLSEVERDLKNSEAASETQ-------TKGKRMVIQEIENSEDEEGKSGR 356
Score = 38.1 bits (87), Expect = 0.019
Identities = 41/138 (29%), Positives = 58/138 (42%), Gaps = 23/138 (16%)
Query: 44 AYSRRGAARFALQKLEEAKKDYERVLELEPNNFEA----------TNELRKISQALASKE 93
AY+ R A LQ A +D E+VLELEP N +A N+LR+ ++ L+
Sbjct: 244 AYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVL 303
Query: 94 NSYPKE--ADIVIKSTEGERKQIEA---QQNKQQAISEKDRGNGFFKEGKYERAIECYTR 148
+ P A + E + K EA Q K + + ++ N +EGK R E
Sbjct: 304 DVEPDNDLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEEGKSGRKHE---- 359
Query: 149 GIAADGANALLPANRAMA 166
DG PA A A
Sbjct: 360 ----DGGGDKKPAEPAGA 373
>gi|24308141 small glutamine-rich tetratricopeptide repeat
(TPR)-containing, beta [Homo sapiens]
Length = 304
Score = 88.6 bits (218), Expect = 1e-17
Identities = 47/114 (41%), Positives = 63/114 (55%)
Query: 127 KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILL 186
KD GN KE Y A++CYT+ I D NA+ NRA A K+ Y +A KDC +AI +
Sbjct: 89 KDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAI 148
Query: 187 DGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 240
D YSKA+ R G A T L K EA ++ L L+P N + L +++L E
Sbjct: 149 DSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLRE 202
Score = 67.0 bits (162), Expect = 4e-11
Identities = 35/89 (39%), Positives = 50/89 (56%)
Query: 1 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 60
++ DP N V NRA+A +L + A DC A+A++ Y+KAY R G A AL K EE
Sbjct: 112 IELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEE 171
Query: 61 AKKDYERVLELEPNNFEATNELRKISQAL 89
A Y++ L+L+P N + L+ Q L
Sbjct: 172 AVTSYQKALDLDPENDSYKSNLKIAEQKL 200
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 82.0 bits (201), Expect = 1e-15
Identities = 64/233 (27%), Positives = 108/233 (46%), Gaps = 28/233 (12%)
Query: 2 DADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALN-------RSYTKAYSRRGAARFA 54
+ DP N TN+A+ YF + C A+ + R KAY+R G + F
Sbjct: 253 ELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFK 312
Query: 55 LQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQI 114
+K ++A Y + L + L+K Q A+ ++K E ER
Sbjct: 313 EEKYKDAIHFYNKSLA----EHRTPDVLKKCQQ------------AEKILK--EQERL-- 352
Query: 115 EAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYE 174
A N A+ EK++GN F++G Y +A++ YT I + +A L +NRA Y K+ +++
Sbjct: 353 -AYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQ 411
Query: 175 EAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQA 227
A KDC + I L+ ++ K + R+ A + +A ++ L L+ K+A
Sbjct: 412 LALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEA 464
Score = 70.9 bits (172), Expect = 3e-12
Identities = 44/165 (26%), Positives = 81/165 (49%), Gaps = 7/165 (4%)
Query: 121 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC 180
+Q K++GN G + A++CY+ I D N +L +NR+ AY K Y++A +D
Sbjct: 2 EQVNELKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDG 61
Query: 181 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 240
+ + L + K ++R+ A FL + EAK+ +E L E N Q L ++ L E
Sbjct: 62 CKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNMEARLAE 121
Query: 241 KGHWDDVFLDSTQRQNVVKPIDNPPHPGS--TKPLKKVIIEETGN 283
+ F++ N+ + +++ P + + P + +IE+ N
Sbjct: 122 R-----KFMNPFNMPNLYQKLESDPRTRTLLSDPTYRELIEQLRN 161
Score = 57.0 bits (136), Expect = 4e-08
Identities = 45/136 (33%), Positives = 66/136 (48%), Gaps = 12/136 (8%)
Query: 4 DPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKK 63
DP+N VL +NR++AY + + A D V L + K YSR+ AA L + EEAK+
Sbjct: 34 DPHNHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKR 93
Query: 64 DYERVLELEPNNFEATNELRKISQALASKE--------NSYPK-EAD---IVIKSTEGER 111
YE L+ E NN + L+ + LA ++ N Y K E+D + S R
Sbjct: 94 TYEEGLKHEANNPQLKEGLQNMEARLAERKFMNPFNMPNLYQKLESDPRTRTLLSDPTYR 153
Query: 112 KQIEAQQNKQQAISEK 127
+ IE +NK + K
Sbjct: 154 ELIEQLRNKPSDLGTK 169
Score = 52.0 bits (123), Expect = 1e-06
Identities = 37/132 (28%), Positives = 69/132 (52%), Gaps = 10/132 (7%)
Query: 4 DPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKK 63
+P + L +NRA+ Y +L +F +A DC + L ++ K Y+R+ AA A++ +A
Sbjct: 390 NPKDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMD 449
Query: 64 DYERVLELEPNNFEATNELRKISQALASKENSYPKE------ADIVIK---STEGERKQI 114
Y++ L+L+ + EA + ++ A ++ +S P++ AD ++ S R +
Sbjct: 450 VYQKALDLDSSCKEAADGYQRCMMAQYNRHDS-PEDVKRRAMADPEVQQIMSDPAMRLIL 508
Query: 115 EAQQNKQQAISE 126
E Q QA+SE
Sbjct: 509 EQMQKDPQALSE 520
Score = 47.4 bits (111), Expect = 3e-05
Identities = 28/103 (27%), Positives = 51/103 (49%), Gaps = 7/103 (6%)
Query: 105 KSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRA 164
K T+ E + + +NK+QA+ EK+ GN +K+ ++ A++ Y + D N N+A
Sbjct: 207 KETKPEPMEEDLPENKKQALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQA 266
Query: 165 MAYLKIQKYEEAEKDCTQAILLD-------GSYSKAFARRGTA 200
Y + Y + + C +AI + +KA+AR G +
Sbjct: 267 AVYFEKGDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNS 309
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 81.6 bits (200), Expect = 1e-15
Identities = 48/155 (30%), Positives = 84/155 (54%), Gaps = 1/155 (0%)
Query: 108 EGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAY 167
E R + A ++A K + N +FK YE AI+ Y++ I + +NA+ NR++AY
Sbjct: 13 EPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAY 72
Query: 168 LKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQA 227
L+ + Y A D T+AI LD Y K + RR + LGK A +D+ETV+ ++P +K A
Sbjct: 73 LRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDA 132
Query: 228 VTELSKIKKELIEKGHWDDVFLDSTQRQNVVKPID 262
+ + K ++++ ++ +++VV +D
Sbjct: 133 KMKYQECNK-IVKQKAFERAIAGDEHKRSVVDSLD 166
Score = 58.2 bits (139), Expect = 2e-08
Identities = 28/92 (30%), Positives = 53/92 (57%)
Query: 1 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 60
++ +P N + NR+ AY R + + A D A+ L++ Y K Y RR A+ AL K
Sbjct: 55 IELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRA 114
Query: 61 AKKDYERVLELEPNNFEATNELRKISQALASK 92
A +DYE V++++P++ +A + ++ ++ + K
Sbjct: 115 ALRDYETVVKVKPHDKDAKMKYQECNKIVKQK 146
>gi|4503729 FK506 binding protein 52 [Homo sapiens]
Length = 459
Score = 77.0 bits (188), Expect = 4e-14
Identities = 58/194 (29%), Positives = 101/194 (52%), Gaps = 23/194 (11%)
Query: 101 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIA------- 151
++ +KS E ++ ++ +++ +Q+ K+RG +FKEGKY++A+ Y + ++
Sbjct: 246 ELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESS 305
Query: 152 -----ADGANALLPA---NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 203
A A AL A N AM +LK+Q + A + C +A+ LD + K RRG A
Sbjct: 306 FSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLA 365
Query: 204 LGKLNEAKQDFETVLLLEPGNKQAVTELS----KIKKELI-EKGHWDDVFLDSTQRQNVV 258
+ A+ DF+ VL L P NK A T+L+ +I+++L EK + ++F + +N
Sbjct: 366 VNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAEEENKA 425
Query: 259 K-PIDNPPHPGSTK 271
K + HP T+
Sbjct: 426 KAEASSGDHPTDTE 439
Score = 54.3 bits (129), Expect = 3e-07
Identities = 34/104 (32%), Positives = 56/104 (53%), Gaps = 7/104 (6%)
Query: 13 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 72
N A + +L+ F+ A CN A+ L+ + K RRG A A+ E A+ D+++VL+L
Sbjct: 324 NLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLY 383
Query: 73 PNNFEATNEL----RKISQALASKENSYPKEADIVIKSTEGERK 112
PNN A +L ++I + LA ++ Y A++ + E E K
Sbjct: 384 PNNKAAKTQLAVCQQRIRRQLAREKKLY---ANMFERLAEEENK 424
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 76.3 bits (186), Expect = 6e-14
Identities = 56/168 (33%), Positives = 80/168 (47%), Gaps = 18/168 (10%)
Query: 73 PNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNG 132
P FEA +++ Q L S + P E D S E ER + E GN
Sbjct: 59 PEIFEAAATGKEMPQDLRSPARTPPSEED----SAEAERLKTE--------------GNE 100
Query: 133 FFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSK 192
K +E A+ Y + I + ANA+ NRA AY K+ Y A +DC +AI +D +YSK
Sbjct: 101 QMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSK 160
Query: 193 AFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 240
A+ R G A + L K EA ++ L L+P N+ + L + +L E
Sbjct: 161 AYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSNLKIAELKLRE 208
Score = 61.6 bits (148), Expect = 2e-09
Identities = 31/75 (41%), Positives = 47/75 (62%)
Query: 1 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 60
++ +P N V NRA+AY +L +A A DC A+ ++ +Y+KAY R G A +L K E
Sbjct: 118 IELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVE 177
Query: 61 AKKDYERVLELEPNN 75
A Y++ LEL+P+N
Sbjct: 178 AVAYYKKALELDPDN 192
>gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 75.9 bits (185), Expect = 8e-14
Identities = 51/162 (31%), Positives = 87/162 (53%), Gaps = 17/162 (10%)
Query: 101 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTR---------G 149
++ +KS E ++ +++ ++ +QA K++G +FK GKY +A+ Y + G
Sbjct: 244 EVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYG 303
Query: 150 IAADGANA----LLPA--NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 203
++ + A LL A N AM YLK+++Y +A + C +A+ LD + K RRG A+
Sbjct: 304 LSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLL 363
Query: 204 LGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWD 245
+ + AK DFE VL + P NK A ++S +K+ E D
Sbjct: 364 MNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERD 405
Score = 51.2 bits (121), Expect = 2e-06
Identities = 35/116 (30%), Positives = 60/116 (51%), Gaps = 4/116 (3%)
Query: 13 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 72
N A Y +L+++ A C+ A+ L+ + K RRG A+ + + E AK D+E+VLE+
Sbjct: 322 NLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVN 381
Query: 73 PNNFEATNELRKISQALASKENSYPKE--ADIVIKSTEGERKQIEAQQNKQQAISE 126
P N A ++ + Q A + N + A++ K E + K+ EA + + SE
Sbjct: 382 PQNKAARLQI-SMCQKKAKEHNERDRRIYANMFKKFAEQDAKE-EANKAMGKKTSE 435
>gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 75.9 bits (185), Expect = 8e-14
Identities = 51/162 (31%), Positives = 87/162 (53%), Gaps = 17/162 (10%)
Query: 101 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTR---------G 149
++ +KS E ++ +++ ++ +QA K++G +FK GKY +A+ Y + G
Sbjct: 244 EVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYG 303
Query: 150 IAADGANA----LLPA--NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 203
++ + A LL A N AM YLK+++Y +A + C +A+ LD + K RRG A+
Sbjct: 304 LSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLL 363
Query: 204 LGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWD 245
+ + AK DFE VL + P NK A ++S +K+ E D
Sbjct: 364 MNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERD 405
Score = 51.2 bits (121), Expect = 2e-06
Identities = 35/116 (30%), Positives = 60/116 (51%), Gaps = 4/116 (3%)
Query: 13 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 72
N A Y +L+++ A C+ A+ L+ + K RRG A+ + + E AK D+E+VLE+
Sbjct: 322 NLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVN 381
Query: 73 PNNFEATNELRKISQALASKENSYPKE--ADIVIKSTEGERKQIEAQQNKQQAISE 126
P N A ++ + Q A + N + A++ K E + K+ EA + + SE
Sbjct: 382 PQNKAARLQI-SMCQKKAKEHNERDRRIYANMFKKFAEQDAKE-EANKAMGKKTSE 435
>gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 75.9 bits (185), Expect = 8e-14
Identities = 51/162 (31%), Positives = 87/162 (53%), Gaps = 17/162 (10%)
Query: 101 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTR---------G 149
++ +KS E ++ +++ ++ +QA K++G +FK GKY +A+ Y + G
Sbjct: 244 EVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYG 303
Query: 150 IAADGANA----LLPA--NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 203
++ + A LL A N AM YLK+++Y +A + C +A+ LD + K RRG A+
Sbjct: 304 LSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLL 363
Query: 204 LGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWD 245
+ + AK DFE VL + P NK A ++S +K+ E D
Sbjct: 364 MNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERD 405
Score = 51.2 bits (121), Expect = 2e-06
Identities = 35/116 (30%), Positives = 60/116 (51%), Gaps = 4/116 (3%)
Query: 13 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 72
N A Y +L+++ A C+ A+ L+ + K RRG A+ + + E AK D+E+VLE+
Sbjct: 322 NLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVN 381
Query: 73 PNNFEATNELRKISQALASKENSYPKE--ADIVIKSTEGERKQIEAQQNKQQAISE 126
P N A ++ + Q A + N + A++ K E + K+ EA + + SE
Sbjct: 382 PQNKAARLQI-SMCQKKAKEHNERDRRIYANMFKKFAEQDAKE-EANKAMGKKTSE 435
>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
A [Homo sapiens]
Length = 608
Score = 75.5 bits (184), Expect = 1e-13
Identities = 45/123 (36%), Positives = 69/123 (56%), Gaps = 6/123 (4%)
Query: 122 QAISEKDRGNGFFKEGKYERAIECYTRGIAADGAN-----ALLPANRAMAYLKIQKYEEA 176
+A + K++GN +FK GKYE+AI+CYT I+ + NRA A+ ++QK++E
Sbjct: 113 RAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEV 172
Query: 177 EKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEP-GNKQAVTELSKIK 235
+DCT+A+ L+ Y KA RR A L E +D V +LE N+Q++ K+
Sbjct: 173 AQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNQQSMLLADKVL 232
Query: 236 KEL 238
K L
Sbjct: 233 KLL 235
Score = 58.5 bits (140), Expect = 1e-08
Identities = 58/223 (26%), Positives = 90/223 (40%), Gaps = 29/223 (13%)
Query: 13 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 72
NRA+A+ +L+K+ DC AV LN Y KA RR A L +E +D V LE
Sbjct: 158 NRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILE 217
Query: 73 PNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNG 132
F+ + S LA K + G+ K E +N++ +
Sbjct: 218 --GFQ-----NQQSMLLADK-----------VLKLLGKEKAKEKYKNREPLMPSPQFIKS 259
Query: 133 FFKEGKYERAIECYTRGIAA----DGANALLPANRAMAYLKIQKYEEAE------KDCTQ 182
+F + + +G + D L YLK ++Y E E +C++
Sbjct: 260 YFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSK 319
Query: 183 AILLDGSY-SKAFARRGTARTFLGKLNEAKQDFETVLLLEPGN 224
I +G Y ++A R T +G N AK D + V+ L+ N
Sbjct: 320 EIDAEGKYMAEALLLRATFYLLIGNANAAKPDLDKVISLKEAN 362
Score = 40.0 bits (92), Expect = 0.005
Identities = 43/217 (19%), Positives = 85/217 (39%), Gaps = 25/217 (11%)
Query: 14 RASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEP 73
R S Y + ++ ++ D N+A ++ Y RG + L ++EEA D++ + L P
Sbjct: 373 RGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVADFDECIRLRP 432
Query: 74 NNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEK----DR 129
+ L + + A +Y T QI+A + + +K
Sbjct: 433 E-----SALAQAQKCFALYRQAY----------TGNNSSQIQAAMKGFEEVIKKFPRCAE 477
Query: 130 GNGFFKEG-----KYERAIECYTRGIAADGANALLPANRAMAYLK-IQKYEEAEKDCTQA 183
G + + ++ +A E Y + I + NA ++ + L+ Q + + ++A
Sbjct: 478 GYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDRGLELISKA 537
Query: 184 ILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLL 220
I +D A+ GT G + +A F + L
Sbjct: 538 IEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINL 574
>gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2
[Homo sapiens]
Length = 438
Score = 70.9 bits (172), Expect = 3e-12
Identities = 47/144 (32%), Positives = 69/144 (47%), Gaps = 10/144 (6%)
Query: 104 IKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADG----ANALL 159
++ K A +N + ++K+ GN FKEG Y+ A E YT + D NA L
Sbjct: 181 LRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKL 240
Query: 160 PANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLL 219
NR K++K ++A +DCT A+ LD +Y KA+ RR + EA +D+E V
Sbjct: 241 YCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ 300
Query: 220 LEPGN------KQAVTELSKIKKE 237
E K A EL K K++
Sbjct: 301 TEKTKEHKQLLKNAQLELKKSKRK 324
Score = 50.8 bits (120), Expect = 3e-06
Identities = 42/136 (30%), Positives = 63/136 (46%), Gaps = 7/136 (5%)
Query: 7 NPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYE 66
N L NR + +L+K A DC AV L+ +Y KAY RR ++ EEA +DYE
Sbjct: 237 NAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYE 296
Query: 67 RVLELEPNNFEATNELRKISQ--ALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAI 124
+V + E + +L K +Q SK Y K + ++E E I+ K+ +
Sbjct: 297 KVYQTEKT--KEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDE---IKKAYRKRALM 351
Query: 125 SEKDRGNGFFKEGKYE 140
DR +G E + E
Sbjct: 352 HHPDRHSGASAEVQKE 367
Score = 48.9 bits (115), Expect = 1e-05
Identities = 44/223 (19%), Positives = 85/223 (38%), Gaps = 35/223 (15%)
Query: 5 PYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKD 64
P N NRA+ L +F A D +V L+ S+ + + R G +L A +
Sbjct: 3 PKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRS 62
Query: 65 YERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAI 124
++R LEL+ N +A E + + + + + I
Sbjct: 63 FQRALELDHKNAQAQQEFKNANAVM------------------------------EYEKI 92
Query: 125 SEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAI 184
+E D F++ + + + C R + A +A + +Y EA+ + +
Sbjct: 93 AETD-----FEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDIL 147
Query: 185 LLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQA 227
+D + + A RG + + +A Q F L + P +++A
Sbjct: 148 RMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKA 190
Score = 40.8 bits (94), Expect = 0.003
Identities = 24/75 (32%), Positives = 35/75 (46%)
Query: 156 NALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFE 215
NA NRA + + ++ EA D Q++ LD S+ + R G LG A + F+
Sbjct: 5 NASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQ 64
Query: 216 TVLLLEPGNKQAVTE 230
L L+ N QA E
Sbjct: 65 RALELDHKNAQAQQE 79
>gi|89179321 smooth muscle cell associated protein-1 isoform 3 [Homo
sapiens]
Length = 929
Score = 70.9 bits (172), Expect = 3e-12
Identities = 43/118 (36%), Positives = 63/118 (53%), Gaps = 3/118 (2%)
Query: 127 KDRGNGFFKEGKYERAIECYTRGIAADGA---NALLPANRAMAYLKIQKYEEAEKDCTQA 183
+ GN FK G Y A+ YT+ + D A+L NRA +LK++ Y++AE + ++A
Sbjct: 10 RKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKA 69
Query: 184 ILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEK 241
I DG KA RR A LG+L++A D + + LEP NK L I ++ EK
Sbjct: 70 IEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEK 127
>gi|29725607 smooth muscle cell associated protein-1 isoform 2 [Homo
sapiens]
Length = 944
Score = 70.9 bits (172), Expect = 3e-12
Identities = 43/118 (36%), Positives = 63/118 (53%), Gaps = 3/118 (2%)
Query: 127 KDRGNGFFKEGKYERAIECYTRGIAADGA---NALLPANRAMAYLKIQKYEEAEKDCTQA 183
+ GN FK G Y A+ YT+ + D A+L NRA +LK++ Y++AE + ++A
Sbjct: 25 RKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKA 84
Query: 184 ILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEK 241
I DG KA RR A LG+L++A D + + LEP NK L I ++ EK
Sbjct: 85 IEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEK 142
>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
[Homo sapiens]
Length = 494
Score = 70.5 bits (171), Expect = 3e-12
Identities = 47/144 (32%), Positives = 69/144 (47%), Gaps = 10/144 (6%)
Query: 104 IKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADG----ANALL 159
++ K A +N + ++K+ GN FKEG Y+ A E YT + D NA L
Sbjct: 237 LRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKL 296
Query: 160 PANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLL 219
NR K++K ++A +DCT A+ LD +Y KA+ RR + EA +D+E V
Sbjct: 297 YCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ 356
Query: 220 LEPGN------KQAVTELSKIKKE 237
E K A EL K K++
Sbjct: 357 TEKTKEHKQLLKNAQLELRKSKRK 380
Score = 68.2 bits (165), Expect = 2e-11
Identities = 41/132 (31%), Positives = 67/132 (50%), Gaps = 2/132 (1%)
Query: 99 EADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANAL 158
E D+V+ +TE E ++ Q+ K++A + K++GN ++ + Y A YT+ I NA
Sbjct: 6 ECDVVMAATEPEL--LDDQEAKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNAS 63
Query: 159 LPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVL 218
NRA + + ++ EA D Q++ LD S+ + R G LG A + F+ L
Sbjct: 64 YYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRAL 123
Query: 219 LLEPGNKQAVTE 230
L+ N QA E
Sbjct: 124 ELDHKNAQAQQE 135
Score = 51.6 bits (122), Expect = 2e-06
Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 15/140 (10%)
Query: 7 NPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYE 66
N L NR + +L+K A DC AV L+ +Y KAY RR ++ EEA +DYE
Sbjct: 293 NAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYE 352
Query: 67 RVLELEPNN------FEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK 120
+V + E A ELRK SK Y K + ++E E I+ K
Sbjct: 353 KVYQTEKTKEHKQLLKNAQLELRK------SKRKDYYKILGVDKNASEDE---IKKAYRK 403
Query: 121 QQAISEKDRGNGFFKEGKYE 140
+ + DR +G E + E
Sbjct: 404 RALMHHPDRHSGASAEVQKE 423
Score = 50.1 bits (118), Expect = 5e-06
Identities = 45/227 (19%), Positives = 87/227 (38%), Gaps = 35/227 (15%)
Query: 1 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 60
+D P N NRA+ L +F A D +V L+ S+ + + R G +L
Sbjct: 55 IDMCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMA 114
Query: 61 AKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK 120
A + ++R LEL+ N +A E + + + +
Sbjct: 115 ACRSFQRALELDHKNAQAQQEFKNANAVM------------------------------E 144
Query: 121 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC 180
+ I+E D F++ + + + C R + A +A + +Y EA+
Sbjct: 145 YEKIAETD-----FEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVA 199
Query: 181 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQA 227
+ + +D + + A RG + + +A Q F L + P +++A
Sbjct: 200 SDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKA 246
>gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens]
Length = 292
Score = 69.7 bits (169), Expect = 6e-12
Identities = 49/172 (28%), Positives = 84/172 (48%), Gaps = 6/172 (3%)
Query: 75 NFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFF 134
+FE K+ NS + + +I+ E E Q+ ++++ K+ GN F
Sbjct: 69 SFEEEPGADKVENKSNEDVNSSELDEEYLIE-LEKNMSDEEKQKRREESTRLKEEGNEQF 127
Query: 135 KEGKYERAIECYTRGIAA-----DGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGS 189
K+G Y A Y+R + ++L +NRA A +K K E A DC++AI L+ S
Sbjct: 128 KKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSKAIQLNPS 187
Query: 190 YSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEK 241
Y +A RR KL+EA +D++++L +P QA ++ K++ E+
Sbjct: 188 YIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPKQIEER 239
Score = 53.1 bits (126), Expect = 6e-07
Identities = 28/91 (30%), Positives = 50/91 (54%)
Query: 9 VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERV 68
+L +NRA+A + K +A +DC+ A+ LN SY +A RR KL+EA +DY+ +
Sbjct: 156 ILFSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSI 215
Query: 69 LELEPNNFEATNELRKISQALASKENSYPKE 99
LE +P+ +A ++ + + + +E
Sbjct: 216 LEKDPSIHQAREACMRLPKQIEERNERLKEE 246
>gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens]
Length = 705
Score = 67.8 bits (164), Expect = 2e-11
Identities = 52/197 (26%), Positives = 90/197 (45%), Gaps = 25/197 (12%)
Query: 99 EADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANAL 158
EA + + + + ++NK A + K++GN F EG YE AI Y+ G+ +
Sbjct: 82 EAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKV 141
Query: 159 LPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVL 218
L NRA AY+K++ YE+A DC A+ D +KA+ G A L + +++ ++ +L
Sbjct: 142 LYTNRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKIL 201
Query: 219 LLEPGNKQAVTELSKIKKELIEKGHWDDVFLD---STQRQNVVKPIDNPPHPGSTKPLKK 275
+ P K + KG+ + V L Q + + +D+ + T
Sbjct: 202 EINP------------KLQTQVKGYLNQVDLQEKADLQEKEAHELLDSGKNTAVT----- 244
Query: 276 VIIEETGNLIQTIDVPD 292
T NL++T+ PD
Sbjct: 245 -----TKNLLETLSKPD 256
Score = 52.0 bits (123), Expect = 1e-06
Identities = 38/130 (29%), Positives = 65/130 (50%), Gaps = 6/130 (4%)
Query: 9 VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERV 68
VL TNRA AY +L+ + A DC A+ + TKAY G A AL+ +++ Y+++
Sbjct: 141 VLYTNRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKI 200
Query: 69 LELEPN-NFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEK 127
LE+ P + L ++ L K + KEA ++ S G+ + +N + +S+
Sbjct: 201 LEINPKLQTQVKGYLNQVD--LQEKADLQEKEAHELLDS--GKNTAV-TTKNLLETLSKP 255
Query: 128 DRGNGFFKEG 137
D+ F+ G
Sbjct: 256 DQIPLFYAGG 265
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 67.0 bits (162), Expect = 4e-11
Identities = 38/120 (31%), Positives = 65/120 (54%)
Query: 107 TEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMA 166
T G+R +K + + + + N +G + AI Y +A D N +L +NR+ A
Sbjct: 42 TIGQRSPDGPVLSKAEFVEKVRQSNQACHDGDFHTAIVLYNEALAVDPQNCILYSNRSAA 101
Query: 167 YLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQ 226
Y+KIQ+Y++A D +A LL+ + KA+ R+G A +LG+ +A F + L +P + Q
Sbjct: 102 YMKIQQYDKALDDAIKARLLNPKWPKAYFRQGVALQYLGRHADALAAFASGLAQDPKSLQ 161
Score = 41.2 bits (95), Expect = 0.002
Identities = 23/74 (31%), Positives = 40/74 (54%)
Query: 4 DPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKK 63
DP N +L +NR++AY +++++ A D A LN + KAY R+G A L + +A
Sbjct: 88 DPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKAYFRQGVALQYLGRHADALA 147
Query: 64 DYERVLELEPNNFE 77
+ L +P + +
Sbjct: 148 AFASGLAQDPKSLQ 161
Score = 32.7 bits (73), Expect = 0.80
Identities = 38/145 (26%), Positives = 63/145 (43%), Gaps = 17/145 (11%)
Query: 43 KAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADI 102
+AY G AL EEA K YE+ L + ++ N ++ ++A N + +
Sbjct: 878 RAYGNLGDCYEALGDYEEAIKYYEQYLSVA----QSLNRMQDQAKAYRGLGNGHRAMGSL 933
Query: 103 VIKSTEGERKQIEAQQ-----NKQQAISEKDRGNGFFKEGKYERAIECYTR--GIAADGA 155
E++ + A + NK QA E G+ + G YE+AI C R IA D
Sbjct: 934 QQALVCFEKRLVVAHELGEAFNKAQAYGE--LGSLHSQLGNYEQAISCLERQLNIARDMK 991
Query: 156 NALLPANRAM----AYLKIQKYEEA 176
+ L ++ A Y ++ +Y+ A
Sbjct: 992 DRALESDAACGLGGVYQQMGEYDTA 1016
>gi|17149853 WAF-1/CIP1 stabilizing protein 39 [Homo sapiens]
Length = 349
Score = 62.0 bits (149), Expect = 1e-09
Identities = 38/130 (29%), Positives = 61/130 (46%), Gaps = 8/130 (6%)
Query: 113 QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIA--------ADGANALLPANRA 164
++E + + A E+ RG F+ G E A CY R + +L AN A
Sbjct: 200 ELETSEKEALAREERARGTELFRAGNPEGAARCYGRALRLLLTLPPPGPPERTVLHANLA 259
Query: 165 MAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGN 224
L + + + A + C + + + + KA RRG A+ LG L +A D + VL ++P N
Sbjct: 260 ACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKN 319
Query: 225 KQAVTELSKI 234
+ A EL K+
Sbjct: 320 RAAQEELGKV 329
Score = 47.8 bits (112), Expect = 2e-05
Identities = 28/81 (34%), Positives = 41/81 (50%)
Query: 5 PYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKD 64
P VL N A+ L + +A C+ + + KA RRG A+ AL LE+A D
Sbjct: 249 PERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATAD 308
Query: 65 YERVLELEPNNFEATNELRKI 85
++VL ++P N A EL K+
Sbjct: 309 LKKVLAIDPKNRAAQEELGKV 329
>gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens]
Length = 929
Score = 61.2 bits (147), Expect = 2e-09
Identities = 40/123 (32%), Positives = 62/123 (50%), Gaps = 3/123 (2%)
Query: 122 QAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPA---NRAMAYLKIQKYEEAEK 178
+A+ K+ GN F+ Y+ A Y++ + ALL NRA LK + Y +A
Sbjct: 5 EAVQLKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAAS 64
Query: 179 DCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKEL 238
D ++AI ++ S KA RR A LGKL++A +D + LEP N+ L ++ +
Sbjct: 65 DASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSI 124
Query: 239 IEK 241
EK
Sbjct: 125 QEK 127
Score = 48.1 bits (113), Expect = 2e-05
Identities = 28/80 (35%), Positives = 43/80 (53%)
Query: 13 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 72
NRA+ + + + A SD + A+ +N S KA RR A L KL++A KD +R LE
Sbjct: 48 NRAACGLKTESYVQAASDASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLE 107
Query: 73 PNNFEATNELRKISQALASK 92
P N LR+++ ++ K
Sbjct: 108 PRNQNFQEMLRRLNTSIQEK 127
>gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens]
Length = 931
Score = 61.2 bits (147), Expect = 2e-09
Identities = 40/123 (32%), Positives = 62/123 (50%), Gaps = 3/123 (2%)
Query: 122 QAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPA---NRAMAYLKIQKYEEAEK 178
+A+ K+ GN F+ Y+ A Y++ + ALL NRA LK + Y +A
Sbjct: 5 EAVQLKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAAS 64
Query: 179 DCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKEL 238
D ++AI ++ S KA RR A LGKL++A +D + LEP N+ L ++ +
Sbjct: 65 DASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSI 124
Query: 239 IEK 241
EK
Sbjct: 125 QEK 127
Score = 48.1 bits (113), Expect = 2e-05
Identities = 28/80 (35%), Positives = 43/80 (53%)
Query: 13 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 72
NRA+ + + + A SD + A+ +N S KA RR A L KL++A KD +R LE
Sbjct: 48 NRAACGLKTESYVQAASDASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLE 107
Query: 73 PNNFEATNELRKISQALASK 92
P N LR+++ ++ K
Sbjct: 108 PRNQNFQEMLRRLNTSIQEK 127
>gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Homo
sapiens]
Length = 420
Score = 58.9 bits (141), Expect = 1e-08
Identities = 47/155 (30%), Positives = 67/155 (43%), Gaps = 22/155 (14%)
Query: 103 VIKSTEGERKQIEAQQNKQQAISE--------------KDRGNGFFKEGKYERAIECYTR 148
V + E KQ EA++ I+E KD+GN F Y AI Y
Sbjct: 256 VAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNL 315
Query: 149 GIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILL--------DGSYSKAFARRGTA 200
I + LL NRA +LK++ +A +D ++A+ L + KA RRGTA
Sbjct: 316 AIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTA 375
Query: 201 RTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIK 235
L E QD+E L ++P NK + KI+
Sbjct: 376 FCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIR 410
Score = 41.2 bits (95), Expect = 0.002
Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 8 PVLPTNRASAYFRLKKFAVAESDCNLAVAL--------NRSYTKAYSRRGAARFALQKLE 59
P+L NRA+ + +LK A D + A+ L + KA+ RRG A L+
Sbjct: 324 PLLYLNRAACHLKLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYV 383
Query: 60 EAKKDYERVLELEPNNFEATNELRKISQALASKE 93
E +DYE L+++P+N + KI + E
Sbjct: 384 EGLQDYEAALKIDPSNKIVQIDAEKIRNVIQGTE 417
Score = 34.3 bits (77), Expect = 0.27
Identities = 19/65 (29%), Positives = 30/65 (46%)
Query: 7 NPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYE 66
NP ++ + F + + A + NLA+ LN Y R A L+ L +A +D
Sbjct: 289 NPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSS 348
Query: 67 RVLEL 71
+ LEL
Sbjct: 349 KALEL 353
>gi|56181387 STIP1 homology and U-box containing protein 1 [Homo
sapiens]
Length = 303
Score = 58.5 bits (140), Expect = 1e-08
Identities = 32/84 (38%), Positives = 46/84 (54%)
Query: 127 KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILL 186
K++GN F KY A CY R I + A+ NRA+ YLK+Q++E+A DC +A+ L
Sbjct: 30 KEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRRALEL 89
Query: 187 DGSYSKAFARRGTARTFLGKLNEA 210
DG KA G + + +EA
Sbjct: 90 DGQSVKAHFFLGQCQLEMESYDEA 113
Score = 35.0 bits (79), Expect = 0.16
Identities = 19/68 (27%), Positives = 34/68 (50%)
Query: 4 DPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKK 63
+P V TNRA Y ++++ A +DC A+ L+ KA+ G + ++ +EA
Sbjct: 56 NPLVAVYYTNRALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIA 115
Query: 64 DYERVLEL 71
+ +R L
Sbjct: 116 NLQRAYSL 123
>gi|19923193 heat shock 70kD protein binding protein [Homo sapiens]
Length = 369
Score = 54.3 bits (129), Expect = 3e-07
Identities = 41/162 (25%), Positives = 75/162 (46%), Gaps = 10/162 (6%)
Query: 60 EAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQN 119
++KK E + EP++ E+ E+ K + + + P+E G+ ++
Sbjct: 61 DSKKVEEDLKADEPSSEESDLEIDK--EGVIEPDTDAPQEM--------GDENAEITEEM 110
Query: 120 KQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKD 179
QA +K +G+ ++AI+ +T I + A+L A RA ++K+QK A +D
Sbjct: 111 MDQANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRD 170
Query: 180 CTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLE 221
C +AI ++ ++ + RG A LG EA D L+
Sbjct: 171 CDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLD 212
Score = 42.7 bits (99), Expect = 8e-04
Identities = 38/146 (26%), Positives = 63/146 (43%), Gaps = 10/146 (6%)
Query: 2 DADPYNP---VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKL 58
DA NP +L RAS + +L+K A DC+ A+ +N + Y RG A L
Sbjct: 139 DAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHW 198
Query: 59 EEAKKDYERVLELEPNNFEAT--NELRKISQALASKENSY-----PKEADIVIKSTEGER 111
EEA D +L+ + + E++ +Q +A Y +E I+ + R
Sbjct: 199 EEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRRKYERKREEREIKERIERVKKAR 258
Query: 112 KQIEAQQNKQQAISEKDRGNGFFKEG 137
++ E Q +++A + G F G
Sbjct: 259 EEHERAQREEEARRQSGAQYGSFPGG 284
>gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo
sapiens]
Length = 504
Score = 53.5 bits (127), Expect = 4e-07
Identities = 60/255 (23%), Positives = 99/255 (38%), Gaps = 41/255 (16%)
Query: 1 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 60
+D DP N + RA+ + + K A D + L +T A +RG KL+E
Sbjct: 64 VDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDE 123
Query: 61 AKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK 120
A+ D+++VL+ P+ EN + +IKS E Q+ +
Sbjct: 124 AEDDFKKVLKSNPS------------------ENEEKEAQSQLIKSD-------EMQRLR 158
Query: 121 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC 180
QA++ F G Y AI + + +A L RA ++K + +A D
Sbjct: 159 SQALNA-------FGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDL 211
Query: 181 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK---- 236
A L ++AF + T LG + + L L+ +K+ ++KK
Sbjct: 212 KAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKL 271
Query: 237 -----ELIEKGHWDD 246
ELI G + D
Sbjct: 272 IESAEELIRDGRYTD 286
Score = 42.4 bits (98), Expect = 0.001
Identities = 31/107 (28%), Positives = 49/107 (45%), Gaps = 3/107 (2%)
Query: 130 GNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGS 189
G G+ A+ + + D N + RA +L + K + A D T+ I L
Sbjct: 44 GKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMD 103
Query: 190 YSKAFARRGTARTFLGKLNEAKQDFETVLLLEPG---NKQAVTELSK 233
++ A +RG GKL+EA+ DF+ VL P K+A ++L K
Sbjct: 104 FTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIK 150
Score = 30.8 bits (68), Expect = 3.0
Identities = 50/253 (19%), Positives = 106/253 (41%), Gaps = 9/253 (3%)
Query: 14 RASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEP 73
RA + + + A SD A L T+A+ + + L E + + L+L+
Sbjct: 194 RAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQ 253
Query: 74 NN---FEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDR- 129
++ F +++K+++ + S E ++ +++ E + + K+R
Sbjct: 254 DHKRCFAHYKQVKKLNKLIESAEELI-RDGRYTDATSKYESVMKTEPSIAEYTVRSKERI 312
Query: 130 GNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGS 189
+ F K+ K AI + + + N +RA AYL + Y+EA +D A + +
Sbjct: 313 CHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETA--QEHN 370
Query: 190 YSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFL 249
+ R G + K+D+ +L ++ K+ E+ K ++L + H D+
Sbjct: 371 ENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKK--QEIIKAYRKLALQWHPDNFQN 428
Query: 250 DSTQRQNVVKPID 262
+ +++ K ID
Sbjct: 429 EEEKKKAEKKFID 441
>gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 51.6 bits (122), Expect = 2e-06
Identities = 53/221 (23%), Positives = 92/221 (41%), Gaps = 14/221 (6%)
Query: 1 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 60
+D DP N + RA ++ A D N A+ ++ + + + RG + +
Sbjct: 1402 IDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTT-AEFLTNRGVIHEFMGHKQN 1460
Query: 61 AKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK 120
A KDY+ + L P K S A + N Y ++++ K ++
Sbjct: 1461 AMKDYQDAITLNP----------KYSLAYFNAGNIYFHHRQFS-QASDYFSKALKFDPEN 1509
Query: 121 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC 180
+ + + N K KYE A E + I + A + NRA Y +++YE AE+D
Sbjct: 1510 EYVLMNRAITNTILK--KYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDL 1567
Query: 181 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLE 221
+A+ L + + + R R +G + EA D+ L LE
Sbjct: 1568 NKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608
Score = 45.4 bits (106), Expect = 1e-04
Identities = 47/232 (20%), Positives = 94/232 (40%), Gaps = 20/232 (8%)
Query: 27 AESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEP------------- 73
A+ D A+ +N +Y KA G A K ++A + ++ +P
Sbjct: 1360 AQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVC 1419
Query: 74 ----NNFEATNELR---KISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISE 126
NNF A ++ KIS N + K + Q N + +++
Sbjct: 1420 LQMGNNFAAMQDINAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAY 1479
Query: 127 KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILL 186
+ GN +F ++ +A + +++ + D N + NRA+ ++KYEEA++D I
Sbjct: 1480 FNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIES 1539
Query: 187 DGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKEL 238
++ + R L + A++D L L+P + +K++ ++
Sbjct: 1540 CPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKI 1591
Score = 38.5 bits (88), Expect = 0.015
Identities = 57/220 (25%), Positives = 96/220 (43%), Gaps = 35/220 (15%)
Query: 44 AYSRRGAARFALQKLEEAKKDYERVLELEP---NNF--------------EATNELRKIS 86
AY RRGA L KL+ A D +RV+ LEP N + EA ++L I
Sbjct: 919 AYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIH 978
Query: 87 QALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAI-SEKDRGNGFFKEGK-YE---- 140
+ + +Y +A+I G++ A N QAI S + +F+ G+ YE
Sbjct: 979 KYNKNNTEAYLSKAEIY----RGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNK 1034
Query: 141 -RAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGT 199
AI+ +++ I D R + Y + + + A +D T + +D S+A RG
Sbjct: 1035 VLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQA---RGQ 1091
Query: 200 ARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELI 239
+ + AK + ++ G ++ELS +++ LI
Sbjct: 1092 YLLMMKYYDLAKFTIYQIAEMDKG----LSELSPMQQALI 1127
Score = 37.7 bits (86), Expect = 0.025
Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 3/89 (3%)
Query: 139 YERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYS---KAFA 195
Y+ AI T I+ D + + NRA+ Y KI++ + A D +LLD + + F
Sbjct: 1215 YKLAITDLTTAISMDKNSYIAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFL 1274
Query: 196 RRGTARTFLGKLNEAKQDFETVLLLEPGN 224
RG LG+ A +DF+ L+ N
Sbjct: 1275 NRGLIYVELGQYGFALEDFKQAALISRTN 1303
Score = 34.7 bits (78), Expect = 0.21
Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 128 DRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLD 187
+RG + + G+Y A+E + + N L AM + +I ++EEA T A+ ++
Sbjct: 1275 NRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKIN 1334
Query: 188 GSYSKAFARRGTARTFLG---KLNEAKQDFETVLLLEP 222
+ A+ RG + G +A++DF L + P
Sbjct: 1335 PCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINP 1372
Score = 34.3 bits (77), Expect = 0.27
Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Query: 170 IQKYEEAEKDCTQAILLDGSYSK-AFARRGTARTFLGKLNEAKQDFETVLLLEP 222
I+ YE K T+ I Y A+ RRG LGKL A D + V+LLEP
Sbjct: 895 IKYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEP 948
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,894,854
Number of Sequences: 37866
Number of extensions: 776158
Number of successful extensions: 3033
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 121
Number of HSP's that attempted gapping in prelim test: 2617
Number of HSP's gapped (non-prelim): 453
length of query: 506
length of database: 18,247,518
effective HSP length: 107
effective length of query: 399
effective length of database: 14,195,856
effective search space: 5664146544
effective search space used: 5664146544
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.