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Search of human proteins with 22547191
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22547191 sorting nexin 15 isoform A [Homo sapiens]
(342 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22547191 sorting nexin 15 isoform A [Homo sapiens] 692 0.0
gi|46370089 sorting nexin 15 isoform B [Homo sapiens] 453 e-128
gi|19923723 ribosomal protein S6 kinase, 52kDa, polypeptide 1 is... 201 8e-52
gi|209915591 ribosomal protein S6 kinase, 52kDa, polypeptide 1 i... 177 1e-44
gi|13899309 ribosomal protein S6 kinase-like 1 [Homo sapiens] 59 6e-09
gi|15553099 sorting nexin 21 isoform a [Homo sapiens] 49 8e-06
gi|33504571 sorting nexin 20 isoform 1 [Homo sapiens] 47 3e-05
gi|150456432 unc-51-like kinase 3 [Homo sapiens] 43 5e-04
gi|23111038 sorting nexin 2 [Homo sapiens] 42 8e-04
gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [H... 42 0.001
gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [H... 42 0.001
gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [H... 42 0.001
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 41 0.001
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 41 0.001
gi|154091028 sorting nexin 29 [Homo sapiens] 41 0.002
gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens] 40 0.003
gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens] 40 0.004
gi|24797153 faciogenital dysplasia protein [Homo sapiens] 39 0.005
gi|24308207 leucine rich repeat containing 47 [Homo sapiens] 39 0.007
gi|157502171 sorting nexin 19 [Homo sapiens] 38 0.011
gi|68800430 HCLS1 binding protein 3 [Homo sapiens] 38 0.015
gi|28144916 lin-37 homolog [Homo sapiens] 38 0.015
gi|224177511 sorting nexin 18 isoform c [Homo sapiens] 37 0.026
gi|116812616 RecQ protein-like 4 [Homo sapiens] 37 0.026
gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ... 37 0.026
gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ... 37 0.026
gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ... 37 0.026
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ... 37 0.026
gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ... 37 0.026
gi|157057545 sorting nexin 18 isoform a [Homo sapiens] 37 0.026
>gi|22547191 sorting nexin 15 isoform A [Homo sapiens]
Length = 342
Score = 692 bits (1785), Expect = 0.0
Identities = 342/342 (100%), Positives = 342/342 (100%)
Query: 1 MSRQAKDDFLRHYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHG 60
MSRQAKDDFLRHYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHG
Sbjct: 1 MSRQAKDDFLRHYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHG 60
Query: 61 DLAYTHRNLFRRLEEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLK 120
DLAYTHRNLFRRLEEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLK
Sbjct: 61 DLAYTHRNLFRRLEEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLK 120
Query: 121 EFFRGGEVTRPLEVSRDLHILPPPLIPTPPPDDPRLSQLLPAERRGLEELEVPVDPPPSS 180
EFFRGGEVTRPLEVSRDLHILPPPLIPTPPPDDPRLSQLLPAERRGLEELEVPVDPPPSS
Sbjct: 121 EFFRGGEVTRPLEVSRDLHILPPPLIPTPPPDDPRLSQLLPAERRGLEELEVPVDPPPSS 180
Query: 181 PAQEALDLLFNCESTEEASGSPARGPLTEAELALFDPFSKEEGAAPSPTHVAELATMEVE 240
PAQEALDLLFNCESTEEASGSPARGPLTEAELALFDPFSKEEGAAPSPTHVAELATMEVE
Sbjct: 181 PAQEALDLLFNCESTEEASGSPARGPLTEAELALFDPFSKEEGAAPSPTHVAELATMEVE 240
Query: 241 SARLDQEPWEPGGQEEEEDGEGGPTPAYLSQATELITQALRDEKAGAYAAALQGYRDGVH 300
SARLDQEPWEPGGQEEEEDGEGGPTPAYLSQATELITQALRDEKAGAYAAALQGYRDGVH
Sbjct: 241 SARLDQEPWEPGGQEEEEDGEGGPTPAYLSQATELITQALRDEKAGAYAAALQGYRDGVH 300
Query: 301 VLLQGVPSDPLPARQEGVKKKAAEYLKRAEEILRLHLSQLPP 342
VLLQGVPSDPLPARQEGVKKKAAEYLKRAEEILRLHLSQLPP
Sbjct: 301 VLLQGVPSDPLPARQEGVKKKAAEYLKRAEEILRLHLSQLPP 342
>gi|46370089 sorting nexin 15 isoform B [Homo sapiens]
Length = 256
Score = 453 bits (1166), Expect = e-128
Identities = 222/227 (97%), Positives = 223/227 (98%)
Query: 1 MSRQAKDDFLRHYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHG 60
MSRQAKDDFLRHYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHG
Sbjct: 1 MSRQAKDDFLRHYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHG 60
Query: 61 DLAYTHRNLFRRLEEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLK 120
DLAYTHRNLFRRLEEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLK
Sbjct: 61 DLAYTHRNLFRRLEEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLK 120
Query: 121 EFFRGGEVTRPLEVSRDLHILPPPLIPTPPPDDPRLSQLLPAERRGLEELEVPVDPPPSS 180
EFFRGGEVTRPLEVSRDLHILPPPLIPTPPPDDPRLSQLLPAERRGLEELEVPVDPPPSS
Sbjct: 121 EFFRGGEVTRPLEVSRDLHILPPPLIPTPPPDDPRLSQLLPAERRGLEELEVPVDPPPSS 180
Query: 181 PAQEALDLLFNCESTEEASGSPARGPLTEAELALFDPFSKEEGAAPS 227
PAQEALDLLFNCESTEEASGSPARGPLTEAELALFDPFSKE P+
Sbjct: 181 PAQEALDLLFNCESTEEASGSPARGPLTEAELALFDPFSKEGDPLPA 227
>gi|19923723 ribosomal protein S6 kinase, 52kDa, polypeptide 1
isoform a [Homo sapiens]
Length = 1066
Score = 201 bits (511), Expect = 8e-52
Identities = 129/334 (38%), Positives = 178/334 (53%), Gaps = 31/334 (9%)
Query: 3 RQAKDDFLRHYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDL 62
R+ D R YTV++P+ HP+GYT YKVTA+ +S+++PEDV+E++VWKRYSDF+KLH +L
Sbjct: 5 RERSADLARFYTVTEPQRHPRGYTVYKVTARVVSRRNPEDVQEIIVWKRYSDFKKLHKEL 64
Query: 63 AYTHRNLFRRLEEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLKEF 122
H+NLFR E FP F + VFGRF+ +VIEERR+ AEDLL+F+ +IPAL NS QL++F
Sbjct: 65 WQIHKNLFRHSELFPPFAKGIVFGRFDETVIEERRQCAEDLLQFSANIPALYNSKQLEDF 124
Query: 123 FRGGEVTRPLEVSRDLHILPPPLIPTPPPDDPRLSQLLPAERRGLEELEVPVDPPPSSPA 182
F+GG + E+ LI T P S + L L V VD
Sbjct: 125 FKGGIINDSSELIGPAEAHSDSLIDT----FPECSTEGFSSDSDLVSLTVDVD------- 173
Query: 183 QEALDLLFNCESTEEASGSPARGPLTEAELALFDPFSKEEGAAPSPTHVAELATMEVESA 242
+ ++ S P+ L L S + A + +E + E E
Sbjct: 174 --------SLAELDDGMASNQNSPIRTFGLNL----SSDSSALGAVASDSEQSKTEEERE 221
Query: 243 RLDQEPWEPGGQEEEEDGEGGPTPAYLSQATELITQALRDEKAGAYAAALQGYRDGVHVL 302
P + + D YL +A ELI AL+ E+ Y AA YR GV +L
Sbjct: 222 SRSLFPGSLKPKLGKRD--------YLEKAGELIKLALKKEEEDDYEAASDFYRKGVDLL 273
Query: 303 LQGVPSDPLPARQEGVKKKAAEYLKRAEEILRLH 336
L+GV + P R+E VK++ AEYL RAE I L+
Sbjct: 274 LEGVQGESSPTRREAVKRRTAEYLMRAESISSLY 307
>gi|209915591 ribosomal protein S6 kinase, 52kDa, polypeptide 1
isoform b [Homo sapiens]
Length = 1054
Score = 177 bits (449), Expect = 1e-44
Identities = 123/334 (36%), Positives = 167/334 (50%), Gaps = 43/334 (12%)
Query: 3 RQAKDDFLRHYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDL 62
R+ D R YTV++P+ HP+GYT YKVTA+ ++VWKRYSDF+KLH +L
Sbjct: 5 RERSADLARFYTVTEPQRHPRGYTVYKVTAR------------IIVWKRYSDFKKLHKEL 52
Query: 63 AYTHRNLFRRLEEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLKEF 122
H+NLFR E FP F + VFGRF+ +VIEERR+ AEDLL+F+ +IPAL NS QL++F
Sbjct: 53 WQIHKNLFRHSELFPPFAKGIVFGRFDETVIEERRQCAEDLLQFSANIPALYNSKQLEDF 112
Query: 123 FRGGEVTRPLEVSRDLHILPPPLIPTPPPDDPRLSQLLPAERRGLEELEVPVDPPPSSPA 182
F+GG + E+ LI T P S + L L V VD
Sbjct: 113 FKGGIINDSSELIGPAEAHSDSLIDT----FPECSTEGFSSDSDLVSLTVDVD------- 161
Query: 183 QEALDLLFNCESTEEASGSPARGPLTEAELALFDPFSKEEGAAPSPTHVAELATMEVESA 242
+ ++ S P+ L L S + A + +E + E E
Sbjct: 162 --------SLAELDDGMASNQNSPIRTFGLNL----SSDSSALGAVASDSEQSKTEEERE 209
Query: 243 RLDQEPWEPGGQEEEEDGEGGPTPAYLSQATELITQALRDEKAGAYAAALQGYRDGVHVL 302
P + + D YL +A ELI AL+ E+ Y AA YR GV +L
Sbjct: 210 SRSLFPGSLKPKLGKRD--------YLEKAGELIKLALKKEEEDDYEAASDFYRKGVDLL 261
Query: 303 LQGVPSDPLPARQEGVKKKAAEYLKRAEEILRLH 336
L+GV + P R+E VK++ AEYL RAE I L+
Sbjct: 262 LEGVQGESSPTRREAVKRRTAEYLMRAESISSLY 295
>gi|13899309 ribosomal protein S6 kinase-like 1 [Homo sapiens]
Length = 541
Score = 58.9 bits (141), Expect = 6e-09
Identities = 32/72 (44%), Positives = 42/72 (58%)
Query: 268 YLSQATELITQALRDEKAGAYAAALQGYRDGVHVLLQGVPSDPLPARQEGVKKKAAEYLK 327
YL A I AL + + Y AA Y++GV VLL+G+ DP R+E VK K +YL+
Sbjct: 49 YLVDAATQIRLALERDVSEDYEAAFNHYQNGVDVLLRGIHVDPNKERREAVKLKITKYLR 108
Query: 328 RAEEILRLHLSQ 339
RAEEI HL +
Sbjct: 109 RAEEIFNCHLQR 120
>gi|15553099 sorting nexin 21 isoform a [Homo sapiens]
Length = 373
Score = 48.5 bits (114), Expect = 8e-06
Identities = 34/116 (29%), Positives = 52/116 (44%), Gaps = 10/116 (8%)
Query: 15 VSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFRRLE 74
V DP P Y Y + + P D + + +RYSDF +LH +L R +
Sbjct: 141 VKDP---PSKYVLYTLA---VIGPGPPDCQPAQISRRYSDFERLHRNLQRQFRGPMAAI- 193
Query: 75 EFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLKEFFRGGEVTR 130
+FPR ++ F A I R + E L +P L ++P L++FF E+ R
Sbjct: 194 ---SFPRKRLRRNFTAETIARRSRAFEQFLGHLQAVPELRHAPDLQDFFVLPELRR 246
>gi|33504571 sorting nexin 20 isoform 1 [Homo sapiens]
Length = 316
Score = 46.6 bits (109), Expect = 3e-05
Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 18/142 (12%)
Query: 13 YTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFRR 72
+ ++ R + +++ V + + D + V+ +RYSDF KL L T R
Sbjct: 78 FEIASARIEERKVSKFVVYQIIVIQTGSFDNNKAVLERRYSDFAKLQKALLKTFREEIED 137
Query: 73 LEEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNS---------PQLKEFF 123
+E FPR + G F +I ERR+ ++ L I + S P+L+E F
Sbjct: 138 VE----FPRKHLTGNFAEEMICERRRALQEYLGLLYAIRCVRRSREFLDFLTRPELREAF 193
Query: 124 ---RGGEVTRPLEVSRDLHILP 142
R G+ R LE+ L +LP
Sbjct: 194 GCLRAGQYPRALELL--LRVLP 213
>gi|150456432 unc-51-like kinase 3 [Homo sapiens]
Length = 472
Score = 42.7 bits (99), Expect = 5e-04
Identities = 24/74 (32%), Positives = 40/74 (54%)
Query: 259 DGEGGPTPAYLSQATELITQALRDEKAGAYAAALQGYRDGVHVLLQGVPSDPLPARQEGV 318
D E P+ L +AT L+ QA++ ++ G AAAL Y + + + + R+E +
Sbjct: 271 DLEHMPSGESLGRATALVVQAVKKDQEGDSAAALSLYCKALDFFVPALHYEVDAQRKEAI 330
Query: 319 KKKAAEYLKRAEEI 332
K K +Y+ RAEE+
Sbjct: 331 KAKVGQYVSRAEEL 344
>gi|23111038 sorting nexin 2 [Homo sapiens]
Length = 519
Score = 42.0 bits (97), Expect = 8e-04
Identities = 39/131 (29%), Positives = 52/131 (39%), Gaps = 22/131 (16%)
Query: 15 VSDPRTHPKG---YTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDLA--YTHRNL 69
VSDP G Y Y+VT + + E V +R+SDF LH LA Y H
Sbjct: 146 VSDPEKVGDGMNAYMAYRVTTK--TSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGY 203
Query: 70 FRRLEEFPAFPRAQVFGRFEASV----------IEERRKGAEDLLRFTVHIPALNNSPQL 119
P P + G + V +E+RR E L+ TV P L P L
Sbjct: 204 I-----VPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDL 258
Query: 120 KEFFRGGEVTR 130
++F E+ R
Sbjct: 259 RQFLESSELPR 269
>gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [Homo
sapiens]
Length = 464
Score = 41.6 bits (96), Expect = 0.001
Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 22/111 (19%)
Query: 19 RTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFRRLEEFPA 78
R K +T YKV E V++RY++F KL+ L ++FPA
Sbjct: 25 REKKKRFTVYKVLVSV-------GRSEWFVFRRYAEFDKLYNTLK----------KQFPA 67
Query: 79 F----PRAQVFG-RFEASVIEERRKGAEDLLRFTVHIPALNNSPQLKEFFR 124
P ++FG F+ I++RR G + ++ V P L N P ++ F +
Sbjct: 68 MALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQ 118
>gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
sapiens]
Length = 496
Score = 41.6 bits (96), Expect = 0.001
Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 22/111 (19%)
Query: 19 RTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFRRLEEFPA 78
R K +T YKV E V++RY++F KL+ L ++FPA
Sbjct: 25 REKKKRFTVYKVLVSV-------GRSEWFVFRRYAEFDKLYNTLK----------KQFPA 67
Query: 79 F----PRAQVFG-RFEASVIEERRKGAEDLLRFTVHIPALNNSPQLKEFFR 124
P ++FG F+ I++RR G + ++ V P L N P ++ F +
Sbjct: 68 MALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQ 118
>gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
sapiens]
Length = 496
Score = 41.6 bits (96), Expect = 0.001
Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 22/111 (19%)
Query: 19 RTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFRRLEEFPA 78
R K +T YKV E V++RY++F KL+ L ++FPA
Sbjct: 25 REKKKRFTVYKVLVSV-------GRSEWFVFRRYAEFDKLYNTLK----------KQFPA 67
Query: 79 F----PRAQVFG-RFEASVIEERRKGAEDLLRFTVHIPALNNSPQLKEFFR 124
P ++FG F+ I++RR G + ++ V P L N P ++ F +
Sbjct: 68 MALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQ 118
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
sapiens]
Length = 2462
Score = 41.2 bits (95), Expect = 0.001
Identities = 42/145 (28%), Positives = 59/145 (40%), Gaps = 29/145 (20%)
Query: 142 PPPLIPTPPPDD-PRLSQLLPAERRGLEELEVPVDPPPSSPAQEALDLLFNCESTEEASG 200
PPP PTPPP+D P ++ PA P P PS+P ++ E EE +
Sbjct: 761 PPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPP----PVVPKEEKEEETAA 816
Query: 201 SPARGPLTEAELALFDPFSKEEGAAPSPTHVAELATMEVESARLDQEPWEPGGQEEEEDG 260
+P EEG P ELA V++ + + EP E E+
Sbjct: 817 AP----------------PVEEGEEQKPPAAEELA---VDTGKAE----EPVKSECTEEA 853
Query: 261 EGGPTPAYLSQATELITQ-ALRDEK 284
E GP ++A E + AL+ EK
Sbjct: 854 EEGPAKGKDAEAAEATAEGALKAEK 878
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
sapiens]
Length = 2524
Score = 41.2 bits (95), Expect = 0.001
Identities = 42/145 (28%), Positives = 59/145 (40%), Gaps = 29/145 (20%)
Query: 142 PPPLIPTPPPDD-PRLSQLLPAERRGLEELEVPVDPPPSSPAQEALDLLFNCESTEEASG 200
PPP PTPPP+D P ++ PA P P PS+P ++ E EE +
Sbjct: 778 PPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPP----PVVPKEEKEEETAA 833
Query: 201 SPARGPLTEAELALFDPFSKEEGAAPSPTHVAELATMEVESARLDQEPWEPGGQEEEEDG 260
+P EEG P ELA V++ + + EP E E+
Sbjct: 834 AP----------------PVEEGEEQKPPAAEELA---VDTGKAE----EPVKSECTEEA 870
Query: 261 EGGPTPAYLSQATELITQ-ALRDEK 284
E GP ++A E + AL+ EK
Sbjct: 871 EEGPAKGKDAEAAEATAEGALKAEK 895
>gi|154091028 sorting nexin 29 [Homo sapiens]
Length = 428
Score = 40.8 bits (94), Expect = 0.002
Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 26/132 (19%)
Query: 48 VWKRYSDFRKLHGDLAYTHRNLFRRLEEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFT 107
+++RY++FR LH L +N + ++ + FP + G +A +EERRK ++ LR
Sbjct: 306 IYRRYTEFRSLHHKL----QNKYPQVRAYN-FPPKKAIGNKDAKFVEERRKQLQNYLRSV 360
Query: 108 VH-----IPALNNSP------QLKEFFRGGEVTRPLEVSRDLHILPPPLIPTPPPDDPRL 156
++ +P SP QL FF ++T P E P P P+L
Sbjct: 361 MNKVIQMVPEFAASPKKETLIQLMPFF--VDITPPGE--------PVNSRPKAASRFPKL 410
Query: 157 SQLLPAERRGLE 168
S+ P E R +E
Sbjct: 411 SRGQPRETRNVE 422
>gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]
Length = 444
Score = 40.0 bits (92), Expect = 0.003
Identities = 23/69 (33%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Query: 265 TPAYLSQATELITQALRDEKAGAYAAALQGYRDGVHVLLQGVPSDPLPAR-QEGVKKKAA 323
T L +A +L ++A +++KAG Y ALQ Y+ V L V + + ++ ++ K
Sbjct: 4 TSPNLQKAIDLASKAAQEDKAGNYEEALQLYQHAVQYFLHVVKYEAQGDKAKQSIRAKCT 63
Query: 324 EYLKRAEEI 332
EYL RAE++
Sbjct: 64 EYLDRAEKL 72
>gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens]
Length = 437
Score = 39.7 bits (91), Expect = 0.004
Identities = 21/69 (30%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Query: 265 TPAYLSQATELITQALRDEKAGAYAAALQGYRDGVHVLLQGVPSDPLPAR-QEGVKKKAA 323
T + L +A +L+T+A ++KA Y AL+ Y+ V L + + + +E ++ K
Sbjct: 2 TTSTLQKAIDLVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCV 61
Query: 324 EYLKRAEEI 332
+YL RAE++
Sbjct: 62 QYLDRAEKL 70
>gi|24797153 faciogenital dysplasia protein [Homo sapiens]
Length = 961
Score = 39.3 bits (90), Expect = 0.005
Identities = 26/66 (39%), Positives = 32/66 (48%), Gaps = 4/66 (6%)
Query: 141 LPPPLIPTPPPDDPRLSQLLPAERRGLEELEVPVDPPPSSPAQEALDLLFNCESTEEASG 200
+PPPL P PPP S+ LPA+ R + L + PSS A +L F E AS
Sbjct: 173 MPPPLEPIPPPP----SRPLPADPRVAKGLAPRAEASPSSAAVSSLIEKFEREPVIVASD 228
Query: 201 SPARGP 206
P GP
Sbjct: 229 RPVPGP 234
>gi|24308207 leucine rich repeat containing 47 [Homo sapiens]
Length = 583
Score = 38.9 bits (89), Expect = 0.007
Identities = 36/122 (29%), Positives = 56/122 (45%), Gaps = 4/122 (3%)
Query: 130 RPLEVSRDLHILPPPLIPTPPPDDPRLSQLLPAERRGLEELEVPVDPPPSSPAQEALDLL 189
R L++S + PP P + P L QL G E+P D +P ++L+L
Sbjct: 102 RVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLT 161
Query: 190 FNC-ESTEEASGSPARGPLTEAELALFDPFSKEEGAAPSPTHVAELATMEVESARLDQEP 248
NC +S P PL +ELA D +E +P H+A L T+++ + +L + P
Sbjct: 162 GNCLDSFPAELFRPGALPLL-SELAAADNCLRE--LSPDIAHLASLKTLDLSNNQLSEIP 218
Query: 249 WE 250
E
Sbjct: 219 AE 220
>gi|157502171 sorting nexin 19 [Homo sapiens]
Length = 992
Score = 38.1 bits (87), Expect = 0.011
Identities = 55/227 (24%), Positives = 91/227 (40%), Gaps = 28/227 (12%)
Query: 50 KRYSDFRKLHG------DLAYTHRNLFRRLEEFPAFPRAQVFGRFEASVIEERRKGAEDL 103
+RY +F L DL +N+ + FP P FG ++ +E R+ E
Sbjct: 581 RRYREFLNLQTRLEEKPDLRKFIKNVKGPKKLFPDLP----FGNMDSDRVEARKSLLESF 636
Query: 104 LRFTVHIPALNNSPQLKEFF------RGGEVTRPLEVSRDLHILPPPLIPTPPPDDPRLS 157
L+ IP + NS +++EF R V +P VSR ++ ++ T PR
Sbjct: 637 LKQLCAIPEIANSEEVQEFLALNTDARIAFVKKPFMVSRIDKMVVSAIVDTLKTAFPRSE 696
Query: 158 QLLPAERRGLEELEVPVDPPPSSPAQEALDLLFNCESTEEASGSPARGPLTEAELALFDP 217
P E L E E P L F+ SPA +TEA+ +
Sbjct: 697 PQSPTEE--LSEAETESKPQTEGKKASKSRLRFSSSKI-----SPALS-VTEAQDKIL-- 746
Query: 218 FSKEEGAAPSPT--HVAELATMEVESARLDQEPWEPGGQEEEEDGEG 262
+ +EG S T A + +E ++ L+ +P + ++ E+ +G
Sbjct: 747 YCLQEGNVESETLSMSAMESFIEKQTKLLEMQPTKAPEKDPEQPPKG 793
>gi|68800430 HCLS1 binding protein 3 [Homo sapiens]
Length = 392
Score = 37.7 bits (86), Expect = 0.015
Identities = 33/105 (31%), Positives = 48/105 (45%), Gaps = 13/105 (12%)
Query: 24 GYTEYKVT-----AQFISKKD-PEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFRRLEEFP 77
G+ EY++ A F S K PEDV + +V K+YS+ + + L+ + P
Sbjct: 37 GHVEYQILVVTRLAAFKSAKHRPEDVVQFLVSKKYSEIEEFYQKLSSRY-----AAASLP 91
Query: 78 AFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLKEF 122
PR +F S I ERR ++LR L SP+L EF
Sbjct: 92 PLPRKVLF--VGESDIRERRAVFNEILRCVSKDAELAGSPELLEF 134
>gi|28144916 lin-37 homolog [Homo sapiens]
Length = 246
Score = 37.7 bits (86), Expect = 0.015
Identities = 35/108 (32%), Positives = 45/108 (41%), Gaps = 18/108 (16%)
Query: 74 EEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLKEFFRGGEVTRPLE 133
E P +P + + R SV E + L P L E G EVT
Sbjct: 111 ENTPLYPICRAWMRNSPSVRERECSPSSPL-------------PPLPEDEEGSEVTN--S 155
Query: 134 VSRDLHILPPPLIPTPPPD--DPRLSQLLPAERRGLEELEVPVDPPPS 179
SRD++ LPPP P PP D R+ L E +G + E P +P PS
Sbjct: 156 KSRDVYKLPPPTPPGPPGDACRSRIPSPLQPEMQGTPDDE-PSEPEPS 202
>gi|224177511 sorting nexin 18 isoform c [Homo sapiens]
Length = 591
Score = 37.0 bits (84), Expect = 0.026
Identities = 30/91 (32%), Positives = 39/91 (42%), Gaps = 19/91 (20%)
Query: 14 TVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFRRL 73
T+ DP T++K +IS K +V V +RY F L+ LA
Sbjct: 279 TIDDPTKQ----TKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLA---------- 324
Query: 74 EEFPAF-----PRAQVFGRFEASVIEERRKG 99
E+FP P Q GRFE I +RRKG
Sbjct: 325 EKFPVISVPHLPEKQATGRFEEDFISKRRKG 355
>gi|116812616 RecQ protein-like 4 [Homo sapiens]
Length = 1208
Score = 37.0 bits (84), Expect = 0.026
Identities = 53/210 (25%), Positives = 72/210 (34%), Gaps = 42/210 (20%)
Query: 143 PPLIPTPPPDDPRLSQLLPAERRGLEEL----------EVPV---DPPPSSP--AQEALD 187
PP +P P P RL L + + L L EVP P P E
Sbjct: 159 PPQLPEPQPRPGRLQHLQASLSQRLGSLDPGWLQRCHSEVPDFLGAPKACRPDLGSEESQ 218
Query: 188 LLFNCESTEEASGSPARGPLTEAELALFDPFSKEEGAAPSPTHVAELATMEVESARLDQE 247
LL ES G+ ++GP E + F S G+ P P+ E R ++E
Sbjct: 219 LLIPGESAVLGPGAGSQGP----EASAFQEVSIRVGS-PQPSSSGG------EKRRWNEE 267
Query: 248 PWEPGGQEEEEDGEGGPTPAYLSQATELITQALRDEKAGAYAAALQGYRDGVHVLLQGVP 307
PWE Q ++E + GP E AGA A + V
Sbjct: 268 PWESPAQVQQESSQAGPP----------------SEGAGAVAVEEDPPGEPVQAQPPQPC 311
Query: 308 SDPLPARQEGVKKKAAEYLKRAEEILRLHL 337
S P R G+ + +AE LH+
Sbjct: 312 SSPSNPRYHGLSPSSQARAGKAEGTAPLHI 341
>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 37.0 bits (84), Expect = 0.026
Identities = 25/102 (24%), Positives = 48/102 (47%), Gaps = 6/102 (5%)
Query: 168 EELEVPVD------PPPSSPAQEALDLLFNCESTEEASGSPARGPLTEAELALFDPFSKE 221
E+LE V+ PPP+ P++ + + + E +G+P+ + + ++ + +KE
Sbjct: 368 EDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKE 427
Query: 222 EGAAPSPTHVAELATMEVESARLDQEPWEPGGQEEEEDGEGG 263
A+ +P + SA + E +EEEE+GE G
Sbjct: 428 VTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAG 469
>gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
isoform 2 [Homo sapiens]
Length = 1512
Score = 37.0 bits (84), Expect = 0.026
Identities = 25/102 (24%), Positives = 48/102 (47%), Gaps = 6/102 (5%)
Query: 168 EELEVPVD------PPPSSPAQEALDLLFNCESTEEASGSPARGPLTEAELALFDPFSKE 221
E+LE V+ PPP+ P++ + + + E +G+P+ + + ++ + +KE
Sbjct: 281 EDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKE 340
Query: 222 EGAAPSPTHVAELATMEVESARLDQEPWEPGGQEEEEDGEGG 263
A+ +P + SA + E +EEEE+GE G
Sbjct: 341 VTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAG 382
>gi|38201625 eukaryotic translation initiation factor 4 gamma, 1
isoform 3 [Homo sapiens]
Length = 1435
Score = 37.0 bits (84), Expect = 0.026
Identities = 25/102 (24%), Positives = 48/102 (47%), Gaps = 6/102 (5%)
Query: 168 EELEVPVD------PPPSSPAQEALDLLFNCESTEEASGSPARGPLTEAELALFDPFSKE 221
E+LE V+ PPP+ P++ + + + E +G+P+ + + ++ + +KE
Sbjct: 204 EDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKE 263
Query: 222 EGAAPSPTHVAELATMEVESARLDQEPWEPGGQEEEEDGEGG 263
A+ +P + SA + E +EEEE+GE G
Sbjct: 264 VTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAG 305
>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 37.0 bits (84), Expect = 0.026
Identities = 25/102 (24%), Positives = 48/102 (47%), Gaps = 6/102 (5%)
Query: 168 EELEVPVD------PPPSSPAQEALDLLFNCESTEEASGSPARGPLTEAELALFDPFSKE 221
E+LE V+ PPP+ P++ + + + E +G+P+ + + ++ + +KE
Sbjct: 368 EDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKE 427
Query: 222 EGAAPSPTHVAELATMEVESARLDQEPWEPGGQEEEEDGEGG 263
A+ +P + SA + E +EEEE+GE G
Sbjct: 428 VTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAG 469
>gi|38201619 eukaryotic translation initiation factor 4 gamma, 1
isoform 4 [Homo sapiens]
Length = 1403
Score = 37.0 bits (84), Expect = 0.026
Identities = 25/102 (24%), Positives = 48/102 (47%), Gaps = 6/102 (5%)
Query: 168 EELEVPVD------PPPSSPAQEALDLLFNCESTEEASGSPARGPLTEAELALFDPFSKE 221
E+LE V+ PPP+ P++ + + + E +G+P+ + + ++ + +KE
Sbjct: 172 EDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKE 231
Query: 222 EGAAPSPTHVAELATMEVESARLDQEPWEPGGQEEEEDGEGG 263
A+ +P + SA + E +EEEE+GE G
Sbjct: 232 VTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAG 273
>gi|157057545 sorting nexin 18 isoform a [Homo sapiens]
Length = 624
Score = 37.0 bits (84), Expect = 0.026
Identities = 30/91 (32%), Positives = 39/91 (42%), Gaps = 19/91 (20%)
Query: 14 TVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFRRL 73
T+ DP T++K +IS K +V V +RY F L+ LA
Sbjct: 279 TIDDPTKQ----TKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLA---------- 324
Query: 74 EEFPAF-----PRAQVFGRFEASVIEERRKG 99
E+FP P Q GRFE I +RRKG
Sbjct: 325 EKFPVISVPHLPEKQATGRFEEDFISKRRKG 355
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.134 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,320,576
Number of Sequences: 37866
Number of extensions: 962075
Number of successful extensions: 5201
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 300
Number of HSP's that attempted gapping in prelim test: 4434
Number of HSP's gapped (non-prelim): 885
length of query: 342
length of database: 18,247,518
effective HSP length: 103
effective length of query: 239
effective length of database: 14,347,320
effective search space: 3429009480
effective search space used: 3429009480
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.