Guide to the Human Genome
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Search of human proteins with 115527104

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|115527104 vitelliform macular dystrophy 2-like 3 isoform 1
[Homo sapiens]
         (668 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|115527104 vitelliform macular dystrophy 2-like 3 isoform 1 [H...  1365   0.0  
gi|115527106 vitelliform macular dystrophy 2-like 3 isoform 2 [H...   910   0.0  
gi|4759310 bestrophin 1 isoform 1 [Homo sapiens]                      512   e-145
gi|119703742 vitelliform macular dystrophy 2-like 1 [Homo sapiens]    508   e-144
gi|23397576 bestrophin 4 [Homo sapiens]                               481   e-136
gi|212720889 bestrophin 1 isoform 2 [Homo sapiens]                    446   e-125
gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens]              43   8e-04
gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens]              43   8e-04
gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens]              43   8e-04
gi|167736355 mucin 4 isoform a [Homo sapiens]                          42   0.002
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        38   0.034
gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]    38   0.034
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        38   0.034
gi|95147555 microtubule-associated protein 1A [Homo sapiens]           38   0.034
gi|161019170 mucin 5AC [Homo sapiens]                                  37   0.077
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       37   0.077
gi|156104862 ankyrin repeat domain 38 [Homo sapiens]                   36   0.10 
gi|239749340 PREDICTED: hypothetical protein XP_002347000 [Homo ...    36   0.13 
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           36   0.13 
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           36   0.13 
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        34   0.38 
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    34   0.38 
gi|119943102 CREB binding protein isoform b [Homo sapiens]             34   0.38 
gi|119943104 CREB binding protein isoform a [Homo sapiens]             34   0.38 
gi|166795252 hypothetical protein LOC23359 [Homo sapiens]              34   0.50 
gi|116284392 mucin 2 precursor [Homo sapiens]                          34   0.50 
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    34   0.50 
gi|87196343 PDZ domain containing 2 [Homo sapiens]                     34   0.50 
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        34   0.50 
gi|167234419 thyroid hormone receptor associated protein 3 [Homo...    34   0.50 

>gi|115527104 vitelliform macular dystrophy 2-like 3 isoform 1 [Homo
           sapiens]
          Length = 668

 Score = 1365 bits (3534), Expect = 0.0
 Identities = 668/668 (100%), Positives = 668/668 (100%)

Query: 1   MTVTYSSKVANATFFGFHRLLLKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGVQKR 60
           MTVTYSSKVANATFFGFHRLLLKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGVQKR
Sbjct: 1   MTVTYSSKVANATFFGFHRLLLKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGVQKR 60

Query: 61  YFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISSSVHGSDEH 120
           YFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISSSVHGSDEH
Sbjct: 61  YFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISSSVHGSDEH 120

Query: 121 GRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTTDERKLFNHLKSPHLK 180
           GRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTTDERKLFNHLKSPHLK
Sbjct: 121 GRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTTDERKLFNHLKSPHLK 180

Query: 181 YWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYTQVV 240
           YWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYTQVV
Sbjct: 181 YWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYTQVV 240

Query: 241 TLAVYTFFFACLIGRQFLDPTKGYAGHDLDLYIPIFTLLQFFFYAGWLKVAEQLINPFGE 300
           TLAVYTFFFACLIGRQFLDPTKGYAGHDLDLYIPIFTLLQFFFYAGWLKVAEQLINPFGE
Sbjct: 241 TLAVYTFFFACLIGRQFLDPTKGYAGHDLDLYIPIFTLLQFFFYAGWLKVAEQLINPFGE 300

Query: 301 DDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARPPYTLAAADYCIPSFL 360
           DDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARPPYTLAAADYCIPSFL
Sbjct: 301 DDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARPPYTLAAADYCIPSFL 360

Query: 361 GSTVQMGLSGSDFPDEEWLWDYEKHGHRHSMIRRVKRFLSAHEHPSSPRRRSYRRQTSDS 420
           GSTVQMGLSGSDFPDEEWLWDYEKHGHRHSMIRRVKRFLSAHEHPSSPRRRSYRRQTSDS
Sbjct: 361 GSTVQMGLSGSDFPDEEWLWDYEKHGHRHSMIRRVKRFLSAHEHPSSPRRRSYRRQTSDS 420

Query: 421 SMFLPRDDLSPARDLLDVPSRNPPRASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTST 480
           SMFLPRDDLSPARDLLDVPSRNPPRASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTST
Sbjct: 421 SMFLPRDDLSPARDLLDVPSRNPPRASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTST 480

Query: 481 LQSLTPQSSVRTSPIKMPLVPEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTE 540
           LQSLTPQSSVRTSPIKMPLVPEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTE
Sbjct: 481 LQSLTPQSSVRTSPIKMPLVPEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTE 540

Query: 541 QQQGPMGSILSPSEKETPPGGPSPQTVSASAEENIFNCEEDPGDTFLKRWSLPGFLGSSH 600
           QQQGPMGSILSPSEKETPPGGPSPQTVSASAEENIFNCEEDPGDTFLKRWSLPGFLGSSH
Sbjct: 541 QQQGPMGSILSPSEKETPPGGPSPQTVSASAEENIFNCEEDPGDTFLKRWSLPGFLGSSH 600

Query: 601 TSLGNLSPDPMSSQPALLIDTETSSEISGINIVAGSRVSSDMLYLMENLDTKETDIIELN 660
           TSLGNLSPDPMSSQPALLIDTETSSEISGINIVAGSRVSSDMLYLMENLDTKETDIIELN
Sbjct: 601 TSLGNLSPDPMSSQPALLIDTETSSEISGINIVAGSRVSSDMLYLMENLDTKETDIIELN 660

Query: 661 KETEESPK 668
           KETEESPK
Sbjct: 661 KETEESPK 668


>gi|115527106 vitelliform macular dystrophy 2-like 3 isoform 2 [Homo
           sapiens]
          Length = 455

 Score =  910 bits (2352), Expect = 0.0
 Identities = 455/506 (89%), Positives = 455/506 (89%), Gaps = 51/506 (10%)

Query: 163 MTTDERKLFNHLKSPHLKYWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCS 222
           MTTDERKLFNHLKSPHLKYWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCS
Sbjct: 1   MTTDERKLFNHLKSPHLKYWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCS 60

Query: 223 LLFGYDWVGIPLVYTQVVTLAVYTFFFACLIGRQFLDPTKGYAGHDLDLYIPIFTLLQFF 282
           LLFGYDWVGIPLVYTQ                                            
Sbjct: 61  LLFGYDWVGIPLVYTQ-------------------------------------------- 76

Query: 283 FYAGWLKVAEQLINPFGEDDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSA 342
                  VAEQLINPFGEDDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSA
Sbjct: 77  -------VAEQLINPFGEDDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSA 129

Query: 343 ARPPYTLAAADYCIPSFLGSTVQMGLSGSDFPDEEWLWDYEKHGHRHSMIRRVKRFLSAH 402
           ARPPYTLAAADYCIPSFLGSTVQMGLSGSDFPDEEWLWDYEKHGHRHSMIRRVKRFLSAH
Sbjct: 130 ARPPYTLAAADYCIPSFLGSTVQMGLSGSDFPDEEWLWDYEKHGHRHSMIRRVKRFLSAH 189

Query: 403 EHPSSPRRRSYRRQTSDSSMFLPRDDLSPARDLLDVPSRNPPRASPTWKKSCFPEGSPTL 462
           EHPSSPRRRSYRRQTSDSSMFLPRDDLSPARDLLDVPSRNPPRASPTWKKSCFPEGSPTL
Sbjct: 190 EHPSSPRRRSYRRQTSDSSMFLPRDDLSPARDLLDVPSRNPPRASPTWKKSCFPEGSPTL 249

Query: 463 HFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMPLVPEVLITAAEAPVPTSGGYHHDS 522
           HFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMPLVPEVLITAAEAPVPTSGGYHHDS
Sbjct: 250 HFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMPLVPEVLITAAEAPVPTSGGYHHDS 309

Query: 523 ATSILSSEFTGVQPSKTEQQQGPMGSILSPSEKETPPGGPSPQTVSASAEENIFNCEEDP 582
           ATSILSSEFTGVQPSKTEQQQGPMGSILSPSEKETPPGGPSPQTVSASAEENIFNCEEDP
Sbjct: 310 ATSILSSEFTGVQPSKTEQQQGPMGSILSPSEKETPPGGPSPQTVSASAEENIFNCEEDP 369

Query: 583 GDTFLKRWSLPGFLGSSHTSLGNLSPDPMSSQPALLIDTETSSEISGINIVAGSRVSSDM 642
           GDTFLKRWSLPGFLGSSHTSLGNLSPDPMSSQPALLIDTETSSEISGINIVAGSRVSSDM
Sbjct: 370 GDTFLKRWSLPGFLGSSHTSLGNLSPDPMSSQPALLIDTETSSEISGINIVAGSRVSSDM 429

Query: 643 LYLMENLDTKETDIIELNKETEESPK 668
           LYLMENLDTKETDIIELNKETEESPK
Sbjct: 430 LYLMENLDTKETDIIELNKETEESPK 455


>gi|4759310 bestrophin 1 isoform 1 [Homo sapiens]
          Length = 585

 Score =  512 bits (1319), Expect = e-145
 Identities = 248/414 (59%), Positives = 302/414 (72%), Gaps = 5/414 (1%)

Query: 1   MTVTYSSKVANATFFGFHRLLLKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGVQKR 60
           MT+TY+S+VANA    F RLLL WRGSIYKLLY EF++F + Y  I  +YRL LT  Q+ 
Sbjct: 1   MTITYTSQVANARLGSFSRLLLCWRGSIYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQL 60

Query: 61  YFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISSSVHGSDEH 120
            FEKL++YCD Y + IP++FVLGFYVTLVV RWWNQ+ NLPWPDRLM L+S  V G DE 
Sbjct: 61  MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ 120

Query: 121 GRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTTDERKLFNHLKSPHLK 180
           GRLLRRTL+RY NL ++LI RSVSTAVYKRFP+  H+V+AGFMT  E K    L  PH  
Sbjct: 121 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM 180

Query: 181 YWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYTQVV 240
           +WVP++WF NL+ KA   GRIRD + LQSL+ EMN  R+ C  L+ YDW+ IPLVYTQVV
Sbjct: 181 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV 240

Query: 241 TLAVYTFFFACLIGRQFLDPTKGYAGHDLDLYIPIFTLLQFFFYAGWLKVAEQLINPFGE 300
           T+AVY+FF  CL+GRQFL+P K Y GH+LDL +P+FT LQFFFY GWLKVAEQLINPFGE
Sbjct: 241 TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGE 300

Query: 301 DDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARPPYTLAAADYCIPSFL 360
           DDDDFETNW +DRNLQVSLLAVDEMH  LP+M+ D+YW+    +PPYT A+A +   SF+
Sbjct: 301 DDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFM 360

Query: 361 GSTVQMGLSGSDFPDEEWLWDYEKHGHRHSMIRRVKRFLSAHEHPSSPRRRSYR 414
           GST  + L+  +    E+  + E     H+ I  + RFL    H   P R + R
Sbjct: 361 GSTFNISLNKEEM---EFQPNQEDEEDAHAGI--IGRFLGLQSHDHHPPRANSR 409


>gi|119703742 vitelliform macular dystrophy 2-like 1 [Homo sapiens]
          Length = 509

 Score =  508 bits (1307), Expect = e-144
 Identities = 244/373 (65%), Positives = 296/373 (79%), Gaps = 1/373 (0%)

Query: 1   MTVTYSSKVANATFFGFHRLLLKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGVQKR 60
           MTVTY+++VANA F GF +LLL WRGSIYKLL+RE + F   Y A+S  YR +LT  QKR
Sbjct: 1   MTVTYTARVANARFGGFSQLLLLWRGSIYKLLWRELLCFLGFYMALSAAYRFVLTEGQKR 60

Query: 61  YFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISSSVHGSDEH 120
           YFEKL IYCD+YA  IPV+FVLGFYVTLVVNRWW+Q++ +P PD LM +++ +VHG D+ 
Sbjct: 61  YFEKLVIYCDQYASLIPVSFVLGFYVTLVVNRWWSQYLCMPLPDALMCVVAGTVHGRDDR 120

Query: 121 GRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTTDERKLFNHLKSPHLK 180
           GRL RRTLMRY  L+++LI RSVSTAV+KRFPT+DHVVEAGFMT +ERK F +L S + K
Sbjct: 121 GRLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFENLNSSYNK 180

Query: 181 YWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYTQVV 240
           YWVP +WF NLA +AR EGRIRD+  L+ L+ E+N +R  C +LF YDW+ +PLVYTQVV
Sbjct: 181 YWVPCVWFSNLAAQARREGRIRDNSALKLLLEELNVFRGKCGMLFHYDWISVPLVYTQVV 240

Query: 241 TLAVYTFFFACLIGRQFLDPTKGYAGHDLDLYIPIFTLLQFFFYAGWLKVAEQLINPFGE 300
           T+A+Y++F ACLIGRQFLDP +GY  HDLDL +PIFTLLQFFFYAGWLKVAEQLINPFGE
Sbjct: 241 TIALYSYFLACLIGRQFLDPAQGYKDHDLDLCVPIFTLLQFFFYAGWLKVAEQLINPFGE 300

Query: 301 DDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARPPYTLAAA-DYCIPSF 359
           DDDDFETN+ IDRN QVS+LAVDEM+  L  ++KD+YWD + AR PYT A       PSF
Sbjct: 301 DDDDFETNFLIDRNFQVSMLAVDEMYDDLAVLEKDLYWDAAEARAPYTAATVFQLRQPSF 360

Query: 360 LGSTVQMGLSGSD 372
            GST  + L+  D
Sbjct: 361 QGSTFDITLAKED 373


>gi|23397576 bestrophin 4 [Homo sapiens]
          Length = 473

 Score =  481 bits (1239), Expect = e-136
 Identities = 237/392 (60%), Positives = 300/392 (76%), Gaps = 18/392 (4%)

Query: 1   MTVTYSSKVANATFFGFHRLLLKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGVQKR 60
           MTV+Y+ KVA A F GF  LLL+WRGSIYKLLY+EF++F  LY  +S+ YRLLLT  Q+ 
Sbjct: 1   MTVSYTLKVAEARFGGFSGLLLRWRGSIYKLLYKEFLLFGALYAVLSITYRLLLTQEQRY 60

Query: 61  YFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISSSVHGSDEH 120
            + +++ YC+R A+ IP++FVLGFYVTLVVNRWW+Q+ ++P PD+LM +IS+SVHG D+ 
Sbjct: 61  VYAQVARYCNRSADLIPLSFVLGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQR 120

Query: 121 GRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTTDERKLFNHLKSPHLK 180
           GRLLRRTL+RY NL S+L+ RSVST V KRFPTM+HVV+AGFM+ +ERK F  LKS   K
Sbjct: 121 GRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESLKSDFNK 180

Query: 181 YWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYTQVV 240
           YWVP +WF NLA +AR +GRIRD + L  L+ E+N+YR+ CS+LF YDW+ IPLVYTQVV
Sbjct: 181 YWVPCVWFTNLAAQARRDGRIRDDIALCLLLEELNKYRAKCSMLFHYDWISIPLVYTQVV 240

Query: 241 TLAVYTFFFACLIGRQFLDPTKGYAG---------------HDLDLYIPIFTLLQFFFYA 285
           T+AVY+FF   L+GRQF++P  G A                 D D+Y+P+ TLLQFFFYA
Sbjct: 241 TIAVYSFFALSLVGRQFVEPEAGAAKPQKLLKPGQEPAPALGDPDMYVPLTTLLQFFFYA 300

Query: 286 GWLKVAEQLINPFGEDDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARP 345
           GWLKVAEQ+INPFGEDDDDFETN  IDRNLQVSLL+VDEM+ +LP  +KD YWD+   +P
Sbjct: 301 GWLKVAEQIINPFGEDDDDFETNQLIDRNLQVSLLSVDEMYQNLPPAEKDQYWDEDQPQP 360

Query: 346 PYTLA-AADYCIPSFLGSTVQMGLSGSDFPDE 376
           PYT+A AA+   PSFLGST  + +  SD P++
Sbjct: 361 PYTVATAAESLRPSFLGSTFNLRM--SDDPEQ 390


>gi|212720889 bestrophin 1 isoform 2 [Homo sapiens]
          Length = 604

 Score =  446 bits (1146), Expect = e-125
 Identities = 213/353 (60%), Positives = 259/353 (73%), Gaps = 5/353 (1%)

Query: 62  FEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISSSVHGSDEHG 121
           FEKL++YCD Y + IP++FVLGFYVTLVV RWWNQ+ NLPWPDRLM L+S  V G DE G
Sbjct: 2   FEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQG 61

Query: 122 RLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTTDERKLFNHLKSPHLKY 181
           RLLRRTL+RY NL ++LI RSVSTAVYKRFP+  H+V+AGFMT  E K    L  PH  +
Sbjct: 62  RLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNMF 121

Query: 182 WVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYTQVVT 241
           WVP++WF NL+ KA   GRIRD + LQSL+ EMN  R+ C  L+ YDW+ IPLVYTQVVT
Sbjct: 122 WVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVVT 181

Query: 242 LAVYTFFFACLIGRQFLDPTKGYAGHDLDLYIPIFTLLQFFFYAGWLKVAEQLINPFGED 301
           +AVY+FF  CL+GRQFL+P K Y GH+LDL +P+FT LQFFFY GWLKVAEQLINPFGED
Sbjct: 182 VAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGED 241

Query: 302 DDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARPPYTLAAADYCIPSFLG 361
           DDDFETNW +DRNLQVSLLAVDEMH  LP+M+ D+YW+    +PPYT A+A +   SF+G
Sbjct: 242 DDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFMG 301

Query: 362 STVQMGLSGSDFPDEEWLWDYEKHGHRHSMIRRVKRFLSAHEHPSSPRRRSYR 414
           ST  + L+  +    E+  + E     H+ I  + RFL    H   P R + R
Sbjct: 302 STFNISLNKEEM---EFQPNQEDEEDAHAGI--IGRFLGLQSHDHHPPRANSR 349


>gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens]
          Length = 278

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 47/156 (30%), Positives = 66/156 (42%), Gaps = 25/156 (16%)

Query: 487 QSSVRTSPIKMPLVPEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPM 546
           QS +R SP   PL  ++  + A +P  T+G    DS+  +L++ F G   + TE Q    
Sbjct: 66  QSKIRQSP--SPLRLQLDRSQATSPGQTNG----DSSLEVLATRFQGSVRTYTESQSSLR 119

Query: 547 GSILSP---SEKETPPGGPSPQTVSASAEENIFNCEE----DPGDTFLKRWSLPGFLGSS 599
            S  SP   S +   P  P P + S + E  I    +     PG     R S  G  GS 
Sbjct: 120 SSYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSR 179

Query: 600 HTSLGNL----------SPDPMSSQPALLIDTETSS 625
              LG            SP P SS+P++  D+E  S
Sbjct: 180 QAGLGRAGDSAVLVLPPSPGPRSSRPSM--DSEGGS 213


>gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens]
          Length = 366

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 47/156 (30%), Positives = 66/156 (42%), Gaps = 25/156 (16%)

Query: 487 QSSVRTSPIKMPLVPEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPM 546
           QS +R SP   PL  ++  + A +P  T+G    DS+  +L++ F G   + TE Q    
Sbjct: 66  QSKIRQSP--SPLRLQLDRSQATSPGQTNG----DSSLEVLATRFQGSVRTYTESQSSLR 119

Query: 547 GSILSP---SEKETPPGGPSPQTVSASAEENIFNCEE----DPGDTFLKRWSLPGFLGSS 599
            S  SP   S +   P  P P + S + E  I    +     PG     R S  G  GS 
Sbjct: 120 SSYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSR 179

Query: 600 HTSLGNL----------SPDPMSSQPALLIDTETSS 625
              LG            SP P SS+P++  D+E  S
Sbjct: 180 QAGLGRAGDSAVLVLPPSPGPRSSRPSM--DSEGGS 213


>gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens]
          Length = 352

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 47/156 (30%), Positives = 66/156 (42%), Gaps = 25/156 (16%)

Query: 487 QSSVRTSPIKMPLVPEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPM 546
           QS +R SP   PL  ++  + A +P  T+G    DS+  +L++ F G   + TE Q    
Sbjct: 66  QSKIRQSP--SPLRLQLDRSQATSPGQTNG----DSSLEVLATRFQGSVRTYTESQSSLR 119

Query: 547 GSILSP---SEKETPPGGPSPQTVSASAEENIFNCEE----DPGDTFLKRWSLPGFLGSS 599
            S  SP   S +   P  P P + S + E  I    +     PG     R S  G  GS 
Sbjct: 120 SSYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSR 179

Query: 600 HTSLGNL----------SPDPMSSQPALLIDTETSS 625
              LG            SP P SS+P++  D+E  S
Sbjct: 180 QAGLGRAGDSAVLVLPPSPGPRSSRPSM--DSEGGS 213


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 56/238 (23%), Positives = 85/238 (35%), Gaps = 48/238 (20%)

Query: 405 PSSPRRRSYRRQTSDSSMFLPRDDLSPARDLLDVPSRNPPRASPTWKKSCFPEGSPTLHF 464
           PS    +  +  TS SS   P  D   ++ +   PS N      T   S  P+ SP +  
Sbjct: 582 PSYSVTQMIKTATSPSSS--PMLDRHTSQQITTAPSTNHSTIHST---STSPQESPAVS- 635

Query: 465 SMGELSTIRETSQTSTLQSLTPQSSVRT---------------SPIKMPLVPEVLITAAE 509
             G     + T ++ T +S++P +  +T               S I     P +      
Sbjct: 636 QRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTISAATTF 695

Query: 510 APVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGP--------MGSILSPSEKETPPGG 561
           AP PT  G+   + T+ L +      PS  +   GP         G++   +   + PGG
Sbjct: 696 APAPTGDGHTTQAPTTALQA-----APSSHDATLGPSGGTSLSKTGALTLANSVVSTPGG 750

Query: 562 P-----------SPQTVSASAEENIFNCEEDPGDTFLKRWSLPGFLGSSHTSLGNLSP 608
           P           SP T +A    +     E  G T   + S P   GS  TS G  +P
Sbjct: 751 PEGQWTSASASTSPDTAAAMTHTHQAESTEASGQT---QTSEPASSGSRTTSAGTATP 805


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 37.7 bits (86), Expect = 0.034
 Identities = 47/206 (22%), Positives = 71/206 (34%), Gaps = 32/206 (15%)

Query: 439 PSRNPPRASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMP 498
           PS      +P+   S F + S T H S     T   ++ ++TL      + V +SP+   
Sbjct: 346 PSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATA 405

Query: 499 LVPEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPSEKE-- 556
             P    +A    V  S  YH                P  T+    P  S  S   +E  
Sbjct: 406 TTPPPARSATSGHVEESTAYHR--------------SPGSTQTMHFPESSTTSGHSEESA 451

Query: 557 ------TPPGGPSPQTVSASAEENIFNCEEDPGDT-FLKRWSLPGFLGSSHTSLGNLSPD 609
                 T     +P T +A A  +  +       T F    ++ G   S  +   + SPD
Sbjct: 452 TFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISG--RSEESKASHSSPD 509

Query: 610 -------PMSSQPALLIDTETSSEIS 628
                  P  S P++L+   T S IS
Sbjct: 510 AMATTVLPAGSTPSVLVGDSTPSPIS 535



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 46/184 (25%), Positives = 73/184 (39%), Gaps = 28/184 (15%)

Query: 439 PSRNPPRASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMP 498
           PS N  R +P    S F E S T H S   + T   +++++T   +   ++  +SP    
Sbjct: 702 PSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQ 761

Query: 499 LV--PEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPSEKE 556
            +  PE   T+      T+    H S T  +SS      PS T         +  P+   
Sbjct: 762 TMHFPESDTTSGRGEESTTS---HSSTTHTISS-----APSTTS------ALVEEPTSYH 807

Query: 557 TPPGG------PSPQTVSASAEENI-FNCEEDPGDTFLKRWSLPGFLGSSHTSLGNLSPD 609
           + PG       P   T S  +EE+I  +  +D   T +    LP    ++   LG  +  
Sbjct: 808 SSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIV----LPA-RSTNSVLLGESTTS 862

Query: 610 PMSS 613
           P+SS
Sbjct: 863 PISS 866



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 41/171 (23%), Positives = 55/171 (32%), Gaps = 31/171 (18%)

Query: 420  SSMFLPRDDLSPARDLL---------DVPSRNPPRASPTWKKSCFPEGSPTLHFSMGELS 470
            SS   PR  LSPA               PS      +P    S F E S T H S   + 
Sbjct: 1115 SSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIP 1174

Query: 471  TIRETSQTSTLQSLTPQSSVRTSPIKMPLVPEVLITAAEAPVPTSGGYHHDSATSILSSE 530
            T   ++ ++T       ++V +SP+     P    +     V  S  YH           
Sbjct: 1175 TTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHS---------- 1224

Query: 531  FTGVQPSKTEQQQGPMGSILSPSEKETPPGGPS--------PQTVSASAEE 573
                 P  T+    P  S  S   +E+     S        P T SA  EE
Sbjct: 1225 ----SPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEE 1271


>gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]
          Length = 861

 Score = 37.7 bits (86), Expect = 0.034
 Identities = 47/206 (22%), Positives = 71/206 (34%), Gaps = 32/206 (15%)

Query: 439 PSRNPPRASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMP 498
           PS      +P+   S F + S T H S     T   ++ ++TL      + V +SP+   
Sbjct: 281 PSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATA 340

Query: 499 LVPEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPSEKE-- 556
             P    +A    V  S  YH                P  T+    P  S  S   +E  
Sbjct: 341 TTPPPARSATSGHVEESTAYHR--------------SPGSTQTMHFPESSTTSGHSEESA 386

Query: 557 ------TPPGGPSPQTVSASAEENIFNCEEDPGDT-FLKRWSLPGFLGSSHTSLGNLSPD 609
                 T     +P T +A A  +  +       T F    ++ G   S  +   + SPD
Sbjct: 387 TFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISG--RSEESKASHSSPD 444

Query: 610 -------PMSSQPALLIDTETSSEIS 628
                  P  S P++L+   T S IS
Sbjct: 445 AMATTVLPAGSTPSVLVGDSTPSPIS 470



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 44/178 (24%), Positives = 67/178 (37%), Gaps = 16/178 (8%)

Query: 439 PSRNPPRASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMP 498
           PS    R +P    S F E S T H S   + T   +++++T   +   ++  +SP    
Sbjct: 637 PSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQ 696

Query: 499 LV--PEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQ-QQGPMGSILSPSEK 555
            +  PE   T+      T+    H S T  +SS      PS T    + P     SP   
Sbjct: 697 TMHFPESDTTSGRGEESTTS---HSSTTHTISS-----APSTTSALVEEPTSYHSSPGST 748

Query: 556 ETPPGGPSPQTVSASAEENIFNCEEDPGDTFLKRWSLPGFLGSSHTSLGNLSPDPMSS 613
            T     S  T   S E    +  +D   T +    LP    ++   LG  +  P+SS
Sbjct: 749 ATTHFPDSSTTSGRSEESTASHSSQDATGTIV----LPA-RSTNSVLLGESTTSPISS 801


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 37.7 bits (86), Expect = 0.034
 Identities = 47/206 (22%), Positives = 71/206 (34%), Gaps = 32/206 (15%)

Query: 439 PSRNPPRASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMP 498
           PS      +P+   S F + S T H S     T   ++ ++TL      + V +SP+   
Sbjct: 425 PSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATA 484

Query: 499 LVPEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPSEKE-- 556
             P    +A    V  S  YH                P  T+    P  S  S   +E  
Sbjct: 485 TTPPPARSATSGHVEESTAYHR--------------SPGSTQTMHFPESSTTSGHSEESA 530

Query: 557 ------TPPGGPSPQTVSASAEENIFNCEEDPGDT-FLKRWSLPGFLGSSHTSLGNLSPD 609
                 T     +P T +A A  +  +       T F    ++ G   S  +   + SPD
Sbjct: 531 TFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISG--RSEESKASHSSPD 588

Query: 610 -------PMSSQPALLIDTETSSEIS 628
                  P  S P++L+   T S IS
Sbjct: 589 AMATTVLPAGSTPSVLVGDSTPSPIS 614



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 50/193 (25%), Positives = 75/193 (38%), Gaps = 21/193 (10%)

Query: 453  SCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTS-------------PIKMPL 499
            + FP+ + T   S  +  T   +SQ ST  +L+P S+  +S               +  L
Sbjct: 4121 TAFPDSTTTSGLS--QEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTL 4178

Query: 500  VPEVLITA----AEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPSEK 555
            +P+  IT+    A  P  +S G  H + T   SS  TG+Q   T  Q  P  S  +PS  
Sbjct: 4179 LPDDTITSGLVEASTPTHSSTGSLHTTLTPA-SSTSTGLQEESTTFQSWPSSSDTTPSPP 4237

Query: 556  ETPPGGPSPQTVSASAEENIFNCEEDPGDTFLKRWSLPGFLGSSHTSLGNLSPDPMSSQP 615
             T        T   S   +          T L R      + SS  + G  +  P  S  
Sbjct: 4238 STTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGT-ALFPTRSAT 4296

Query: 616  ALLIDTETSSEIS 628
            ++L+   T+S IS
Sbjct: 4297 SVLVGEPTTSPIS 4309



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 37/155 (23%), Positives = 51/155 (32%), Gaps = 23/155 (14%)

Query: 439  PSRNPPRASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMP 498
            PS      +P    S F E S T H S     T   ++ ++TL      ++V +SP+   
Sbjct: 1836 PSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 1895

Query: 499  LVPEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPSEKETP 558
              P    +     V  S  YH                P  T+    P  S  S   +E+ 
Sbjct: 1896 TTPSPARSTTSGLVEESTAYHS--------------SPGSTQTMHFPESSTASGRSEESR 1941

Query: 559  PGGPS--------PQTVSASAEENIFNCEEDPGDT 585
                S        P T SA  EE   +    PG T
Sbjct: 1942 TSHSSTTHTISSPPSTTSALVEEPT-SYHSSPGST 1975



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 37/147 (25%), Positives = 54/147 (36%), Gaps = 7/147 (4%)

Query: 439  PSRNPPRASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMP 498
            P+      +P    S F E S T H S     T   ++ ++TL      ++V +SP+   
Sbjct: 4476 PNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 4535

Query: 499  LVPEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPSEKETP 558
              P    +     V  S  YH    +S  S++      S T   +G   +    S   T 
Sbjct: 4536 TTPSPARSTTSGLVEESTTYH----SSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTI 4591

Query: 559  PGGPSPQTVSASAEENIFNCEEDPGDT 585
               PS  T SA  EE   +    PG T
Sbjct: 4592 SSAPS--TTSALVEEPT-SYHSSPGST 4615



 Score = 34.3 bits (77), Expect = 0.38
 Identities = 37/147 (25%), Positives = 54/147 (36%), Gaps = 7/147 (4%)

Query: 439  PSRNPPRASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMP 498
            P+      +P    S F E S T H S     T   ++ ++TL      ++V +SP+   
Sbjct: 3393 PNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 3452

Query: 499  LVPEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPSEKETP 558
              P    +     V  S  YH    +S  S++      S T   +G   +    S   T 
Sbjct: 3453 TTPSPARSTTSGLVEESTTYH----SSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTI 3508

Query: 559  PGGPSPQTVSASAEENIFNCEEDPGDT 585
               PS  T SA  EE   +    PG T
Sbjct: 3509 SSAPS--TTSALVEEPT-SYHSSPGST 3532



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 43/169 (25%), Positives = 63/169 (37%), Gaps = 13/169 (7%)

Query: 439 PSRNPPRASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMP 498
           PS    R +P    S F E S T H S   + T   +++++T   +   ++  +SP    
Sbjct: 781 PSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQ 840

Query: 499 LV--PEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQ-QQGPMGSILSPSEK 555
            +  PE   T+      T+    H S T  +SS      PS T    + P     SP   
Sbjct: 841 TMHFPESDTTSGRGEESTTS---HSSTTHTISS-----APSTTSALVEEPTSYHSSPGST 892

Query: 556 ETPPGGPSPQTVSASAEENIFNCEEDPGDTFL--KRWSLPGFLGSSHTS 602
            T     S  T   S E    +  +D   T +   R +    LG S TS
Sbjct: 893 ATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTS 941



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 43/188 (22%), Positives = 61/188 (32%), Gaps = 34/188 (18%)

Query: 406  SSPRRRSYRRQTSDSSMFLPRDDLSPARDLLDV---PSRNPPRASPTWKKSCFP------ 456
            S+   RS     S SS       + PAR    V    S   P +S + + +  P      
Sbjct: 4624 STTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTP 4683

Query: 457  ---EGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMPLVPEVLITAAEAPVP 513
               E S T H S     T   ++ ++TL      ++V +SP+     P    +     V 
Sbjct: 4684 GLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVE 4743

Query: 514  TSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPSEKETPPGGPS--------PQ 565
             S  YH                P  T+    P  S  S   +E+     S        P 
Sbjct: 4744 ESTAYHS--------------SPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPS 4789

Query: 566  TVSASAEE 573
            T SA  EE
Sbjct: 4790 TTSALVEE 4797


>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
          Length = 2803

 Score = 37.7 bits (86), Expect = 0.034
 Identities = 53/209 (25%), Positives = 76/209 (36%), Gaps = 57/209 (27%)

Query: 419  DSSMFLPRDDLSP----ARDLLDVPSRNPPRASPTWKKSC-----------FPEGSP--T 461
            D  +  P   LSP    +  +L VPS +     PT K  C           +PE SP  T
Sbjct: 1135 DEVLRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVSPEDT 1194

Query: 462  LHFSMGELSTIRETSQTSTLQSLTPQS-------------------------SVRTSPIK 496
               S+ E S  +ETS   + + L+P+S                         S  T+P+ 
Sbjct: 1195 QSLSLSEESPSKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTSHHTAPMS 1254

Query: 497  MPLVPEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPM-------GSI 549
            +P  P     AA A  PT G   + + T I         P+ +     P        G+I
Sbjct: 1255 VP-EPH----AATASPPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGNGKYLPGAI 1309

Query: 550  LSPSEKETPPG---GPSPQTVSASAEENI 575
             SP E    P      SP+++   A E+I
Sbjct: 1310 TSPDEHILTPDSSFSKSPESLPGPALEDI 1338


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 36.6 bits (83), Expect = 0.077
 Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 14/135 (10%)

Query: 446  ASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMPLVPEVLI 505
            ++P    +  P  +P   + + + +T   T+  ST  + TP S++RT+P      P+VL 
Sbjct: 2580 STPATSSTATPSSTPGTTWILTKPTTTATTT-ASTGSTATPTSTLRTAP-----PPKVLT 2633

Query: 506  TAAEAPVPTSGGYHHDS----ATSILSSEFTGVQPSKTEQQQGPMGSILSP----SEKET 557
            T A  P  TS      S    AT++ +   T   P+ T     P  S+ +     S+  T
Sbjct: 2634 TTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTT 2693

Query: 558  PPGGPSPQTVSASAE 572
            P    S  T S++ E
Sbjct: 2694 PTATMSTATPSSTPE 2708



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 11/112 (9%)

Query: 446  ASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMPLVPEVLI 505
            ++P    +  P  +P   + + EL+T   T+  ST  + TP S+  T+P      P+VL 
Sbjct: 4703 STPATSSTAMPSSTPGTTWILTELTTTATTT-ASTGSTATPSSTPGTAP-----PPKVLT 4756

Query: 506  TAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPSEKET 557
            + A  P  TS       ATS  S       P  T        + ++P    T
Sbjct: 4757 SPATTPTATS-----SKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSST 4803


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 36.6 bits (83), Expect = 0.077
 Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 14/135 (10%)

Query: 446  ASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMPLVPEVLI 505
            ++P    +  P  +P   + + + +T   T+  ST  + TP S++RT+P      P+VL 
Sbjct: 1890 STPATSSTATPSSTPGTTWILTKPTTTATTT-ASTGSTATPTSTLRTAP-----PPKVLT 1943

Query: 506  TAAEAPVPTSGGYHHDS----ATSILSSEFTGVQPSKTEQQQGPMGSILSP----SEKET 557
            T A  P  TS      S    AT++ +   T   P+ T     P  S+ +     S+  T
Sbjct: 1944 TTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTT 2003

Query: 558  PPGGPSPQTVSASAE 572
            P    S  T S++ E
Sbjct: 2004 PTATMSTATPSSTPE 2018



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 11/112 (9%)

Query: 446  ASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMPLVPEVLI 505
            ++P    +  P  +P   + + EL+T   T+  ST  + TP S+  T+P      P+VL 
Sbjct: 4233 STPATSSTAMPSSTPGTTWILTELTTTATTT-ASTGSTATPSSTPGTAP-----PPKVLT 4286

Query: 506  TAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPSEKET 557
            + A  P  TS       ATS  S       P  T        + ++P    T
Sbjct: 4287 SPATTPTATS-----SKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSST 4333



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 11/87 (12%)

Query: 471  TIRETSQTSTLQSLTPQSSVRTSPIKMPLVPEVLITAAEAPVPTSGGYHHDSATSILSSE 530
            T   T+ T+T  +  P S+  T+PI     P VL T A  P  TS      + +S L + 
Sbjct: 2694 TTTATTITATGSTTNPSSTPGTTPI-----PPVLTTTATTPAATSSTV---TPSSALGTT 2745

Query: 531  FTGVQPSKTEQQQGPMGSILSPSEKET 557
             T   P+ T       G  LSPS   T
Sbjct: 2746 HTPPVPNTTATTH---GRSLSPSSPHT 2769


>gi|156104862 ankyrin repeat domain 38 [Homo sapiens]
          Length = 995

 Score = 36.2 bits (82), Expect = 0.10
 Identities = 37/151 (24%), Positives = 67/151 (44%), Gaps = 17/151 (11%)

Query: 493 SPIKMPLVPEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGS---- 548
           SP +  L+P++ +      V TS      S  S LS+E   ++ + TEQ+ GP G     
Sbjct: 467 SPAERVLLPQLSLPQGPEQVLTS------SVHSFLSTELR-IEEAGTEQEGGPQGGTRGA 519

Query: 549 --ILSPSEKETPPGGPSPQTVSASAEENIFNCEEDPGDTFLKRW--SLPGFLGSSHTSLG 604
              L  S+++TPP G    + +   +E+       P D  + ++   +   L      L 
Sbjct: 520 GGFLWGSDRKTPPAGREETSSNLPGKEHPGRPPSSPTDATIGQYVKKIQELLQEQWNCLE 579

Query: 605 NLSPDPMSS--QPALLIDTETSSEISGINIV 633
           +  P+  S+  QPA  + +  S  +S +N++
Sbjct: 580 HGYPELASAIKQPASKLSSIQSQLLSSLNLL 610


>gi|239749340 PREDICTED: hypothetical protein XP_002347000 [Homo
           sapiens]
          Length = 349

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 37/127 (29%), Positives = 54/127 (42%), Gaps = 10/127 (7%)

Query: 438 VPSRNPPRASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTSTLQ--SLTPQSSVRTSPI 495
           +P R+P   +P ++ S FP   P+   S       R +S+T+  Q  SL  Q   RT+P 
Sbjct: 96  LPGRHPSGTAP-FQDSSFPGQHPSRIASFQG----RHSSRTAPFQDGSLPGQHPSRTAPF 150

Query: 496 KMPLVPEVLITAAEAPVP--TSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPS 553
           +   +P  L  +  AP    T  G H         S F G  PS+    QG   S  +P 
Sbjct: 151 QDDTLPGWL-PSRTAPFQDNTLPGRHPSGTAPFQDSSFPGQHPSRIASFQGRHSSRTAPF 209

Query: 554 EKETPPG 560
           +  + PG
Sbjct: 210 QDGSLPG 216


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 53/239 (22%), Positives = 93/239 (38%), Gaps = 35/239 (14%)

Query: 361 GSTVQMGLSGSDFPDEEWLWDYEKHGHRHSMIRRVKRFLSAHEHPSSPRRRSYRRQTSD- 419
           GS     +S    P +E      K   +H   ++ K+     ++   P     + ++ D 
Sbjct: 86  GSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDD 145

Query: 420 ------SSMFLPRDDLSPARDLLDVPSRNPPRASPTWKKSCFPEGSPTLHFSMGE---LS 470
                 S  FL + D  P+   L++P+R     S T +        P +   + E   L 
Sbjct: 146 GNIDLESDSFL-KFDSEPSAVALELPTR-AFGPSETNESPAVVLEPPVVSMEVSEPHILE 203

Query: 471 TIRETSQTSTLQS-----LTPQSSVRTSPIKMPLVPEVLITAAEAPVPTSG--------- 516
           T++  ++T+ L       ++ QS    + +  P + ++L + A APVPT+          
Sbjct: 204 TLKPATKTAELSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTLVLKSSEPV 263

Query: 517 ---GYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPSE-----KETPPG-GPSPQT 566
                 +   + + S E T  +PSK    + P+  +L PSE      ETP    P P T
Sbjct: 264 VTMSVEYQMKSVLKSVESTSPEPSKIMLVEPPVAKVLEPSETLVVSSETPTEVYPEPST 322


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 53/239 (22%), Positives = 93/239 (38%), Gaps = 35/239 (14%)

Query: 361 GSTVQMGLSGSDFPDEEWLWDYEKHGHRHSMIRRVKRFLSAHEHPSSPRRRSYRRQTSD- 419
           GS     +S    P +E      K   +H   ++ K+     ++   P     + ++ D 
Sbjct: 86  GSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDD 145

Query: 420 ------SSMFLPRDDLSPARDLLDVPSRNPPRASPTWKKSCFPEGSPTLHFSMGE---LS 470
                 S  FL + D  P+   L++P+R     S T +        P +   + E   L 
Sbjct: 146 GNIDLESDSFL-KFDSEPSAVALELPTR-AFGPSETNESPAVVLEPPVVSMEVSEPHILE 203

Query: 471 TIRETSQTSTLQS-----LTPQSSVRTSPIKMPLVPEVLITAAEAPVPTSG--------- 516
           T++  ++T+ L       ++ QS    + +  P + ++L + A APVPT+          
Sbjct: 204 TLKPATKTAELSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTLVLKSSEPV 263

Query: 517 ---GYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPSE-----KETPPG-GPSPQT 566
                 +   + + S E T  +PSK    + P+  +L PSE      ETP    P P T
Sbjct: 264 VTMSVEYQMKSVLKSVESTSPEPSKIMLVEPPVAKVLEPSETLVVSSETPTEVYPEPST 322


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 34.3 bits (77), Expect = 0.38
 Identities = 44/184 (23%), Positives = 71/184 (38%), Gaps = 22/184 (11%)

Query: 406  SSPRRRSYRRQTSDSSMFLPRDDLSPARDLLDVPSRNPPRAS-PTWKKSC---------F 455
            S P  ++ R + + SS+  P   +  A +L    S + P  S PT++ +           
Sbjct: 1221 SEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKT 1280

Query: 456  PEG----SPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMPLVPEVLI-TAAEA 510
            PE     +P L  S      +     + T +S T  SSV+T    +P  PE+ I T+ + 
Sbjct: 1281 PEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQ 1340

Query: 511  PVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPSEKETPPGGPSPQTVSAS 570
            PV           TS  +   T +   K  +   P+   L PS     P  P P + +  
Sbjct: 1341 PVT-------PKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATR 1393

Query: 571  AEEN 574
              +N
Sbjct: 1394 GRKN 1397



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 41/166 (24%), Positives = 64/166 (38%), Gaps = 16/166 (9%)

Query: 414  RRQTSDSSMFLPR----DDLSPARDLLDVPSRNPPRASPTWKKSCFPEGSPTLHFSMGEL 469
            R+   D S   P      +L P      + +R   R +P    S  PE  P+   S  + 
Sbjct: 1079 RKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPST--STAQP 1136

Query: 470  STIRETSQTSTLQSLTPQSSVRTSPIKMPLVPEVL-ITAAEAPVPTSGGYHHDSATSILS 528
             T + TSQ +  +S T +SSV+T    +P  PE+   T+ + PV +         TS ++
Sbjct: 1137 VTPKPTSQAT--RSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTS-------EPTSQVT 1187

Query: 529  SEFTGVQPSKTEQQQGPMGSILSPSEKETPPGGPSPQTVSASAEEN 574
                     KT +   P    L PS     P    P + +    +N
Sbjct: 1188 RGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKN 1233


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 34.3 bits (77), Expect = 0.38
 Identities = 34/143 (23%), Positives = 47/143 (32%), Gaps = 22/143 (15%)

Query: 439  PSRNPPRASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMP 498
            PS      +P    S F E S T H S     T   ++ ++TL      ++V +SP+   
Sbjct: 1323 PSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 1382

Query: 499  LVPEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPSEKETP 558
              P    +     V  S  YH                P  T+    P  S  S   +E+ 
Sbjct: 1383 TTPSPARSTTSGLVEESTAYHS--------------SPGSTQTMHFPESSTASGRSEESR 1428

Query: 559  PGGPS--------PQTVSASAEE 573
                S        P T SA  EE
Sbjct: 1429 TSHSSTTHTISSPPSTTSALVEE 1451



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 43/169 (25%), Positives = 63/169 (37%), Gaps = 13/169 (7%)

Query: 439 PSRNPPRASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMP 498
           PS    R +P    S F E S T H S   + T   +++++T   +   ++  +SP    
Sbjct: 268 PSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQ 327

Query: 499 LV--PEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQ-QQGPMGSILSPSEK 555
            +  PE   T+      T+    H S T  +SS      PS T    + P     SP   
Sbjct: 328 TMHFPESDTTSGRGEESTTS---HSSTTHTISS-----APSTTSALVEEPTSYHSSPGST 379

Query: 556 ETPPGGPSPQTVSASAEENIFNCEEDPGDTFL--KRWSLPGFLGSSHTS 602
            T     S  T   S E    +  +D   T +   R +    LG S TS
Sbjct: 380 ATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTS 428


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 34.3 bits (77), Expect = 0.38
 Identities = 65/280 (23%), Positives = 101/280 (36%), Gaps = 44/280 (15%)

Query: 360 LGSTVQMGLSGSDFPDEEWLWDYEKHGHRHSMIRRV---KRFLSAHEHPSSPRRRSYRR- 415
           +GS   M +S S  P    +       H ++M+ +     +FL  ++ PSS    S    
Sbjct: 718 MGSVPGMAISPSRMPQPPNMMG----AHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMG 773

Query: 416 ----QTSDSSMFLPRDDLSPARDLLDVPSRNPPRASPTWKKSCFPEGSPTLHFSMGELST 471
               QT  S   +P   L    ++L       P+AS   +  C P     LH +    ST
Sbjct: 774 QPPAQTGVSQGQVPGAALPNPLNMLG------PQAS---QLPCPPVTQSPLHPTPPPAST 824

Query: 472 IRETSQTSTLQSLTPQSSVRTSPIKMPLVPEVLITAAEAPVPTSGGYHHDSATSILSSEF 531
               +   +LQ  TP       P         + ++ + P PT G     + T    +  
Sbjct: 825 ---AAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQ 881

Query: 532 TGVQPSKTEQQQGPM--GSILSP---SEKETPPGGPSPQTVSASAEENIFNCEEDPGDTF 586
              Q   T Q Q P+   S+ +P    ++ TP     P T  + A  +I N         
Sbjct: 882 AAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDN--------- 932

Query: 587 LKRWSLPGFLGSSHTSLGNLSPDPMSSQPALLIDTETSSE 626
             R   P  + S+ T+    S  P    P L + TET +E
Sbjct: 933 --RVPTPSSVASAETN----SQQPGPDVPVLEMKTETQAE 966



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 33/148 (22%), Positives = 56/148 (37%), Gaps = 10/148 (6%)

Query: 439 PSRNPPR-ASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKM 497
           P   PP+ A+PT   +       T   + G + +  +T  T T+Q+   Q+ V   P   
Sbjct: 837 PGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAA-QAQVTPQPQTP 895

Query: 498 PLVPEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPSEKET 557
              P V    +    PT    H     + LS      Q + +   + P  S ++ +E  +
Sbjct: 896 VQPPSVATPQSSQQQPTP--VHAQPPGTPLS------QAAASIDNRVPTPSSVASAETNS 947

Query: 558 PPGGPSPQTVSASAEENIFNCEEDPGDT 585
              GP    +    E    + E DPG++
Sbjct: 948 QQPGPDVPVLEMKTETQAEDTEPDPGES 975


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 34.3 bits (77), Expect = 0.38
 Identities = 65/280 (23%), Positives = 101/280 (36%), Gaps = 44/280 (15%)

Query: 360  LGSTVQMGLSGSDFPDEEWLWDYEKHGHRHSMIRRV---KRFLSAHEHPSSPRRRSYRR- 415
            +GS   M +S S  P    +       H ++M+ +     +FL  ++ PSS    S    
Sbjct: 756  MGSVPGMAISPSRMPQPPNMMG----AHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMG 811

Query: 416  ----QTSDSSMFLPRDDLSPARDLLDVPSRNPPRASPTWKKSCFPEGSPTLHFSMGELST 471
                QT  S   +P   L    ++L       P+AS   +  C P     LH +    ST
Sbjct: 812  QPPAQTGVSQGQVPGAALPNPLNMLG------PQAS---QLPCPPVTQSPLHPTPPPAST 862

Query: 472  IRETSQTSTLQSLTPQSSVRTSPIKMPLVPEVLITAAEAPVPTSGGYHHDSATSILSSEF 531
                +   +LQ  TP       P         + ++ + P PT G     + T    +  
Sbjct: 863  ---AAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQ 919

Query: 532  TGVQPSKTEQQQGPM--GSILSP---SEKETPPGGPSPQTVSASAEENIFNCEEDPGDTF 586
               Q   T Q Q P+   S+ +P    ++ TP     P T  + A  +I N         
Sbjct: 920  AAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDN--------- 970

Query: 587  LKRWSLPGFLGSSHTSLGNLSPDPMSSQPALLIDTETSSE 626
              R   P  + S+ T+    S  P    P L + TET +E
Sbjct: 971  --RVPTPSSVASAETN----SQQPGPDVPVLEMKTETQAE 1004



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 33/148 (22%), Positives = 56/148 (37%), Gaps = 10/148 (6%)

Query: 439  PSRNPPR-ASPTWKKSCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKM 497
            P   PP+ A+PT   +       T   + G + +  +T  T T+Q+   Q+ V   P   
Sbjct: 875  PGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAA-QAQVTPQPQTP 933

Query: 498  PLVPEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPSEKET 557
               P V    +    PT    H     + LS      Q + +   + P  S ++ +E  +
Sbjct: 934  VQPPSVATPQSSQQQPTP--VHAQPPGTPLS------QAAASIDNRVPTPSSVASAETNS 985

Query: 558  PPGGPSPQTVSASAEENIFNCEEDPGDT 585
               GP    +    E    + E DPG++
Sbjct: 986  QQPGPDVPVLEMKTETQAEDTEPDPGES 1013


>gi|166795252 hypothetical protein LOC23359 [Homo sapiens]
          Length = 539

 Score = 33.9 bits (76), Expect = 0.50
 Identities = 44/187 (23%), Positives = 73/187 (39%), Gaps = 31/187 (16%)

Query: 395 VKRFLSAHEHPSSPR----RRSYRRQTSDSSMFLPRDDLSPARDLLDVPSRNPPRASPTW 450
           ++ FL    HP++P       +   QT D   F+P             P   PP   P +
Sbjct: 208 LQMFLPQRSHPANPTCVTPHGTVLHQTLDFDEFIP-------------PLPPPPYYPPEY 254

Query: 451 KKSCFPEGSPTLH--FSMGELSTIRETSQTST-----LQSLTPQSSVRTSP--IKMPLVP 501
             +   E    LH  F+     T+ + +  S       +   P  +V   P   ++  + 
Sbjct: 255 TCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEAVVGQPPASQVTSIG 314

Query: 502 EVLITAAEAPVPTSGGYHHD---SATSILSSEFTGVQPSKTEQQQGPMGSILSPSEKETP 558
           + +  ++     TS G+       +TS+L SE T   P  +    GP+G+  +PSE   P
Sbjct: 315 QQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTAT-PGSSPSPDGPVGAP-APSEPALP 372

Query: 559 PGGPSPQ 565
           PG  SP+
Sbjct: 373 PGHVSPE 379


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 33.9 bits (76), Expect = 0.50
 Identities = 25/100 (25%), Positives = 38/100 (38%), Gaps = 9/100 (9%)

Query: 476  SQTSTLQSLTPQSSVRTSPI----KMPLVPEVLITAAEAPVPTSGGYHHDSATSILSSEF 531
            +QT T   +T  ++V  +P     + P    +  T    P PT  G    + T I ++  
Sbjct: 4124 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4183

Query: 532  TGVQPSKTEQQQGP-----MGSILSPSEKETPPGGPSPQT 566
                P+ T  Q GP        I   +    PP   +PQT
Sbjct: 4184 VTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQT 4223


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 33.9 bits (76), Expect = 0.50
 Identities = 37/125 (29%), Positives = 50/125 (40%), Gaps = 13/125 (10%)

Query: 440 SRNPPRASPTWKKS-CFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMP 498
           +R P RASPT K S   P G+P+     G  ST   T  +ST       S   T P   P
Sbjct: 341 TRTPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSST------ASPTGTPPRASP 394

Query: 499 LVPEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPSEKETP 558
                  +    P P +      S TSI   + T   P++T  +  P G+      + +P
Sbjct: 395 TGTPSTASLTRKP-PRASPTGMLSRTSITKMDST-ASPTRTPPRASPTGT----PPRASP 448

Query: 559 PGGPS 563
            G PS
Sbjct: 449 TGTPS 453



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 32/112 (28%), Positives = 44/112 (39%), Gaps = 11/112 (9%)

Query: 439 PSRNPPRASPT-WKKSCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRT-SPIK 496
           P+R PPRASPT       P G+P+     G  ST   T   ST    +P  S  T SP  
Sbjct: 430 PTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTASPTGSPST---ASPTGSPSTASPTG 486

Query: 497 MPLVPEVLITAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGS 548
            P        A+    P+        +T+ ++   +   P+ T     P GS
Sbjct: 487 SP------SRASLTRTPSRASLTKMESTASITRTPSRASPTWTPSTASPTGS 532


>gi|87196343 PDZ domain containing 2 [Homo sapiens]
          Length = 2839

 Score = 33.9 bits (76), Expect = 0.50
 Identities = 44/204 (21%), Positives = 76/204 (37%), Gaps = 27/204 (13%)

Query: 404  HPSSPRRRSYRRQTSDSS-------MFLPRDDLSPARDLLDVPSRNPPRAS-----PTWK 451
            HP     R  RR  S  S         LP+   SP+   L +  +NPP  S        K
Sbjct: 2384 HPGDAAARLLRRSLSSCSENQSEAGTLLPQMAKSPSIMTLTISRQNPPETSSKGSDSELK 2443

Query: 452  KSCFPEGSPTLHFSMGELSTIRETSQTSTLQSLTPQSSVRTSPIKMPLVPEVLITAAEAP 511
            KS  P G PT   ++   S ++    +      +P S  +   ++   +P++    +E  
Sbjct: 2444 KSLGPLGIPTPTMTLA--SPVKRNKSSVRHTQPSPVSRSKLQELRALSMPDLDKLCSED- 2500

Query: 512  VPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGSILSPSE--KETPPGGPSPQTVSA 569
                   +    +++L      + P ++     P G +  P +      PGG  P+T +A
Sbjct: 2501 -------YSAGPSAVLFKTELEITPRRSPGP--PAGGVSCPEKGGNRACPGGSGPKTSAA 2551

Query: 570  SAEENIFNCEEDPGD-TFLKRWSL 592
                +  +  E   D  F + WS+
Sbjct: 2552 ETPSSASDTGEAAQDLPFRRSWSV 2575


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 33.9 bits (76), Expect = 0.50
 Identities = 56/204 (27%), Positives = 78/204 (38%), Gaps = 51/204 (25%)

Query: 396 KRFLSAHEHPSSPRRRSYRRQTSDSSMFLPRDDLSPARD--------LLDVPSRNPPRAS 447
           KR  S    P+   RR++R  ++DS+      D S +R            +  R+P  AS
Sbjct: 244 KRKRSRSTTPAPKSRRAHRSTSADSAS---SSDTSRSRSRSAAAKTHTTALAGRSPSPAS 300

Query: 448 PTWKKSCFPEGSPTLHFSMGELSTIRETS-QTSTLQSLTP----------QSSVRTSPIK 496
               +   P   P      G  ST R +S +T+T Q  +P          +S+ R SP  
Sbjct: 301 GRRGEGDAPFSEP------GTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPS- 353

Query: 497 MPLVPEVLITAAEAPVPTS------GGYHHDSATSILSSEFTGVQPSKTEQQQGPMGSIL 550
               PE   T  E P PT       GG     AT+ LS E   V P           S  
Sbjct: 354 ----PERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQE--PVNPP----------SEA 397

Query: 551 SPSEKETPPGGPSPQTVSASAEEN 574
           SP+   +PP  P     S+S+E +
Sbjct: 398 SPTRDRSPPKSPEKLPQSSSSESS 421


>gi|167234419 thyroid hormone receptor associated protein 3 [Homo
           sapiens]
          Length = 955

 Score = 33.9 bits (76), Expect = 0.50
 Identities = 51/206 (24%), Positives = 78/206 (37%), Gaps = 30/206 (14%)

Query: 397 RFLSAHEHPSSPRRRSYRRQTSDSSMFLP-------RDDLSPARDLLDVPSRNPP--RAS 447
           R  S H    S +R+S + + S S    P       + D +  +      S++     +S
Sbjct: 161 RSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESS 220

Query: 448 PTWKKSCFPEGSPTLHFSMGELSTI-RETSQTSTLQSLTPQS-SVRTSPIKMPLVPEVLI 505
             W  + +  GS +   ++ ELS   R  +  S LQS+  +  S R SP+  P  P    
Sbjct: 221 KPWPDATYGTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSST 280

Query: 506 TAAEAPVPTSGGYHHDSATSILSSEFTGVQPSKTEQQQGPMGS-ILSPSEKETPPGGPSP 564
           +   + +P+  GY                  S T Q Q   GS  LSPS K++P G   P
Sbjct: 281 SQMGSTLPSGAGYQ-----------------SGTHQGQFDHGSGSLSPS-KKSPVGKSPP 322

Query: 565 QTVSASAEENIFNCEEDPGDTFLKRW 590
            T S              G  + KR+
Sbjct: 323 STGSTYGSSQKEESAASGGAAYTKRY 348


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,671,766
Number of Sequences: 37866
Number of extensions: 1327220
Number of successful extensions: 4796
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 121
Number of HSP's that attempted gapping in prelim test: 4559
Number of HSP's gapped (non-prelim): 360
length of query: 668
length of database: 18,247,518
effective HSP length: 109
effective length of query: 559
effective length of database: 14,120,124
effective search space: 7893149316
effective search space used: 7893149316
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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