Guide to the Human Genome
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Search of human proteins with 223633995

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223633995 Hsp70 subfamily B suppressor 1-like protein
isoform 3 [Homo sapiens]
         (632 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223633995 Hsp70 subfamily B suppressor 1-like protein isoform...  1242   0.0  
gi|5729864 Hsp70 subfamily B suppressor 1-like protein isoform 1...   291   2e-78
gi|223555963 Hsp70 subfamily B suppressor 1-like protein isoform...   187   3e-47
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    43   8e-04
gi|150170670 piccolo isoform 2 [Homo sapiens]                          40   0.009
gi|150378539 piccolo isoform 1 [Homo sapiens]                          40   0.009
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]                   40   0.009
gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens]                  39   0.015
gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens]                  39   0.015
gi|153251840 zinc finger protein 839 [Homo sapiens]                    35   0.16 
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap...    33   0.80 
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap...    33   0.80 
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa...    33   0.80 
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa...    33   0.80 
gi|30795196 LIM homeobox protein 2 [Homo sapiens]                      33   1.0  
gi|24430212 interleukin 23 receptor precursor [Homo sapiens]           32   1.4  
gi|46359075 zinc finger protein 423 [Homo sapiens]                     32   1.4  
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]         32   1.4  
gi|170016069 zinc finger, CCHC domain containing 2 [Homo sapiens]      32   1.4  
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    32   1.8  
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    32   1.8  
gi|38327034 ubiquitination factor E4B isoform 2 [Homo sapiens]         32   1.8  
gi|157739864 ubiquitination factor E4B isoform 1 [Homo sapiens]        32   1.8  
gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]     32   2.3  
gi|20302168 toll-like receptor 8 [Homo sapiens]                        32   2.3  
gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens]     32   2.3  
gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]       32   2.3  
gi|110611228 utrophin [Homo sapiens]                                   32   2.3  
gi|12056971 anaphase promoting complex subunit 1 [Homo sapiens]        32   2.3  
gi|31559815 keratin 26 [Homo sapiens]                                  32   2.3  

>gi|223633995 Hsp70 subfamily B suppressor 1-like protein isoform 3
           [Homo sapiens]
          Length = 632

 Score = 1242 bits (3213), Expect = 0.0
 Identities = 632/632 (100%), Positives = 632/632 (100%)

Query: 1   MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTAAQFIYSRRDKPSVEPVEEYDYED 60
           MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTAAQFIYSRRDKPSVEPVEEYDYED
Sbjct: 1   MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTAAQFIYSRRDKPSVEPVEEYDYED 60

Query: 61  LKESSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVL 120
           LKESSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVL
Sbjct: 61  LKESSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVL 120

Query: 121 EQDRVQSLKDKNEATVSTGKIAKGVLFSSSEVSADNVQSSYPQSANHLDYSSKPFDFASS 180
           EQDRVQSLKDKNEATVSTGKIAKGVLFSSSEVSADNVQSSYPQSANHLDYSSKPFDFASS
Sbjct: 121 EQDRVQSLKDKNEATVSTGKIAKGVLFSSSEVSADNVQSSYPQSANHLDYSSKPFDFASS 180

Query: 181 VGKYGLSHNSSVPTHCLLHRKKKLDTRKSEKKLESCKLTKELSLANLIHDMSRDSCESQP 240
           VGKYGLSHNSSVPTHCLLHRKKKLDTRKSEKKLESCKLTKELSLANLIHDMSRDSCESQP
Sbjct: 181 VGKYGLSHNSSVPTHCLLHRKKKLDTRKSEKKLESCKLTKELSLANLIHDMSRDSCESQP 240

Query: 241 SVRLSSTDSLESLLSKNLDADLLRPHASECISKDDSAFKEIPDLKTIIIKGTTPNNSLYI 300
           SVRLSSTDSLESLLSKNLDADLLRPHASECISKDDSAFKEIPDLKTIIIKGTTPNNSLYI
Sbjct: 241 SVRLSSTDSLESLLSKNLDADLLRPHASECISKDDSAFKEIPDLKTIIIKGTTPNNSLYI 300

Query: 301 QNNSLSDFQNIPVQDSLGSSNNPLYLTSSLENMTVDNLNASKETEVGNVSLVEQSAKNHT 360
           QNNSLSDFQNIPVQDSLGSSNNPLYLTSSLENMTVDNLNASKETEVGNVSLVEQSAKNHT
Sbjct: 301 QNNSLSDFQNIPVQDSLGSSNNPLYLTSSLENMTVDNLNASKETEVGNVSLVEQSAKNHT 360

Query: 361 FKNDNLQFSQCESPSLTELFQEHKENNISQCFTLSDLCNQSSASFTDLSLGSFPLSQLAN 420
           FKNDNLQFSQCESPSLTELFQEHKENNISQCFTLSDLCNQSSASFTDLSLGSFPLSQLAN
Sbjct: 361 FKNDNLQFSQCESPSLTELFQEHKENNISQCFTLSDLCNQSSASFTDLSLGSFPLSQLAN 420

Query: 421 RCQSSPGISELTGSLSSLAFHKASPTRDLENLSLSELIAETIDVDNSQIKKESFEVSLSE 480
           RCQSSPGISELTGSLSSLAFHKASPTRDLENLSLSELIAETIDVDNSQIKKESFEVSLSE
Sbjct: 421 RCQSSPGISELTGSLSSLAFHKASPTRDLENLSLSELIAETIDVDNSQIKKESFEVSLSE 480

Query: 481 VRSPGIDSNIDLSVLIKNPDFVPKPVVDPSIAPSSRTKVLSSKLGKNSNFAKDNKKNNKG 540
           VRSPGIDSNIDLSVLIKNPDFVPKPVVDPSIAPSSRTKVLSSKLGKNSNFAKDNKKNNKG
Sbjct: 481 VRSPGIDSNIDLSVLIKNPDFVPKPVVDPSIAPSSRTKVLSSKLGKNSNFAKDNKKNNKG 540

Query: 541 SLTRKPPFSLSWTKALAARPSAFASTLCLRYPLKSCKRRTLDLYKTFLYSRQVQDVKDKE 600
           SLTRKPPFSLSWTKALAARPSAFASTLCLRYPLKSCKRRTLDLYKTFLYSRQVQDVKDKE
Sbjct: 541 SLTRKPPFSLSWTKALAARPSAFASTLCLRYPLKSCKRRTLDLYKTFLYSRQVQDVKDKE 600

Query: 601 ISPLVAITPFDFKSASPDDIVKANQKKAFTRE 632
           ISPLVAITPFDFKSASPDDIVKANQKKAFTRE
Sbjct: 601 ISPLVAITPFDFKSASPDDIVKANQKKAFTRE 632


>gi|5729864 Hsp70 subfamily B suppressor 1-like protein isoform 1
           [Homo sapiens]
          Length = 684

 Score =  291 bits (744), Expect = 2e-78
 Identities = 144/144 (100%), Positives = 144/144 (100%)

Query: 1   MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTAAQFIYSRRDKPSVEPVEEYDYED 60
           MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTAAQFIYSRRDKPSVEPVEEYDYED
Sbjct: 1   MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTAAQFIYSRRDKPSVEPVEEYDYED 60

Query: 61  LKESSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVL 120
           LKESSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVL
Sbjct: 61  LKESSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVL 120

Query: 121 EQDRVQSLKDKNEATVSTGKIAKG 144
           EQDRVQSLKDKNEATVSTGKIAKG
Sbjct: 121 EQDRVQSLKDKNEATVSTGKIAKG 144


>gi|223555963 Hsp70 subfamily B suppressor 1-like protein isoform 2
           [Homo sapiens]
          Length = 642

 Score =  187 bits (474), Expect = 3e-47
 Identities = 102/144 (70%), Positives = 102/144 (70%), Gaps = 42/144 (29%)

Query: 1   MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTAAQFIYSRRDKPSVEPVEEYDYED 60
           MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPST                        
Sbjct: 1   MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPST------------------------ 36

Query: 61  LKESSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVL 120
                             ARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVL
Sbjct: 37  ------------------ARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVL 78

Query: 121 EQDRVQSLKDKNEATVSTGKIAKG 144
           EQDRVQSLKDKNEATVSTGKIAKG
Sbjct: 79  EQDRVQSLKDKNEATVSTGKIAKG 102


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 84/372 (22%), Positives = 141/372 (37%), Gaps = 24/372 (6%)

Query: 121 EQDRVQSLKDKNEATVSTGKIAKGVLFSSSEVSADNVQSSYPQSANHLDYSSKPFDFA-S 179
           + D+  S K K++++ S    +     S+S  S+D+  S    S +  D  S   D + S
Sbjct: 536 DNDKSDSGKGKSDSSDSDSSDS-----SNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDS 590

Query: 180 SVGKYGLSHNSSVPTHCLLHRKKKLDTRKSEKKLESCKLTKELSLANLIHDMSRDSCESQ 239
           S      S NSS  +           +  S+ K +S K   + S +    D   DS +S 
Sbjct: 591 SDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDS----DSKSDSSDSN 646

Query: 240 PSVRLSSTDSLESLLSKNLDADLLRPHASECISKDDSAFKEIPDLKTIIIKGTTPNNSLY 299
            S    ++DS +S  S N         +    S D S      D         + ++S  
Sbjct: 647 SSDSSDNSDSSDSSNSSN--------SSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNS 698

Query: 300 IQNNSLSDFQNIPVQDSLGSSN-NPLYLTSSLENMTVDNLNASKETEVGNVSLVEQSAKN 358
            +++  SD  +    DS  SSN N     SS  + + D+ N+S  ++  + S    S+ +
Sbjct: 699 SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758

Query: 359 HTFKNDNLQFSQCESPSLTELFQEHKENNISQCFTLSDLCNQS-SASFTDLSLGSFPLSQ 417
               N +      +S   ++       N+ S     SD  N S S++ +D S  S     
Sbjct: 759 SDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDS 818

Query: 418 LANRCQSSPGISELTGSLSSLAFHKASPTRDLENLSLSELIAETIDVDNSQIKKESFEVS 477
            ++    S   S+ + S +S     +S + D  +   S       D  NS    +S + S
Sbjct: 819 DSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS----NRSDSSNSSDSSDSSDSS 874

Query: 478 LSEVRSPGIDSN 489
            S   S   DSN
Sbjct: 875 NSSDSSDSSDSN 886



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 72/342 (21%), Positives = 129/342 (37%), Gaps = 15/342 (4%)

Query: 148  SSSEVSADNVQSSYPQSANHLDYSSKPFDFASSVGKYGLSHNSSVPTHCLLHRKKKLDTR 207
            S+S  S+D+  SS   S+N  D SS   D + S      S +S            + D+ 
Sbjct: 804  SNSSDSSDSSDSSDSDSSNSSD-SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSS 862

Query: 208  KSEKKLESCKLTKELSLANLIHDMSRDSCESQPSVRLSSTDSLESLLSKNLDADLLRPHA 267
             S    +S   +          D S  S  ++ S    S+DS  S  S + D+      +
Sbjct: 863  NSSDSSDSSDSSNS-------SDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSS 915

Query: 268  SECISKDDSAFKEIPDLKTIIIKGTTPNNSLYIQNNSLSDFQNIPVQDSLGSSNNPLYLT 327
                S D S      D         + ++S    ++  SD  N     +   S+N    +
Sbjct: 916  DSSNSSDSSESSNSSD------NSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 969

Query: 328  SSLENMTVDNLNASKETEVGNVSLVEQSAKNHTFKNDNLQFSQCESPSLTELFQEHKENN 387
             S  + + D+ N+S  ++  + S    S+ +    + +      +S + ++       +N
Sbjct: 970  DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029

Query: 388  ISQCFTLSDLCNQSSASFTDLSLGSFPLSQLANRCQSSPGISELTGSLSSLAFHKASPTR 447
             S     SD  + S +S +  S  S   S  ++   SS   S+ + S  S    ++S + 
Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS-SDSSDSSDSSDSSESSDSS 1088

Query: 448  DLENLSLSELIAETIDVDNSQIKKESFEVSLSEVRSPGIDSN 489
            D  N S S   +++ D  +S    +S + S S   S   DS+
Sbjct: 1089 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 95/494 (19%), Positives = 175/494 (35%), Gaps = 17/494 (3%)

Query: 13   DEDFEDDDLYGQSVEDDYCISPSTAAQFIYSRRDKPSVEPVEEYDYEDLKESSNSVSNHQ 72
            D D  D +    S   D   S S+ +    S     S +  +  D  D  +SS+S S+  
Sbjct: 568  DSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSS 627

Query: 73   LSGFDQARLYSCLDHMREVLGDAVPDEILIEAV----LKNKFDVQKALSGVLEQDRVQSL 128
             S  D +   S  D       D+  +    ++       +  D   +       D   S 
Sbjct: 628  KSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSS 687

Query: 129  KDKNEATVSTGKIAKGVLFSSSEVSAD-----NVQSSYPQSANHLDYSSKPFDFASSVGK 183
               + +  S    +     SS   S+D     N  SS   S+N  D S       SS   
Sbjct: 688  DSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS 747

Query: 184  YGLSHNSSVPTHCLLHRKKKLDTRKSEKKLESCKLTKELSLANLIHDM-------SRDSC 236
               + + S  +    +     D+  S    +S   +     +N            S +S 
Sbjct: 748  DSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSS 807

Query: 237  ESQPSVRLSSTDSLESLLSKNLDADLLRPHASECISKDDSAFKEIPDLKTIIIKGTTPNN 296
            +S  S   S +DS  S  S N        ++S+     DS+     D         + ++
Sbjct: 808  DSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS 867

Query: 297  SLYIQNNSLSDFQNIPVQDSLGSSNNPLYLTSSLENMTVDNLNASKETEVGNVSLVEQSA 356
            S    +++ SD  +    +   +S++    ++S ++ + D+ N+S  ++  N S   +S+
Sbjct: 868  SDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESS 927

Query: 357  KNHTFKNDNLQFSQCESPSLTELFQEHKENNISQCFTLSDLCNQSSASFTDLSLGSFPL- 415
             +    N +   +  +S   ++       +N S     SD  + +S+  +D S  S    
Sbjct: 928  NSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSD 987

Query: 416  SQLANRCQSSPGISELTGSLSSLAFHKASPTRDLENLSLSELIAETIDVDNSQIKKESFE 475
            S  ++    S   S  + S  S     +S + D  N S S   +++ D  +S    +S +
Sbjct: 988  SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047

Query: 476  VSLSEVRSPGIDSN 489
             S S   S   DS+
Sbjct: 1048 SSDSSDSSNSSDSS 1061



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 85/394 (21%), Positives = 152/394 (38%), Gaps = 25/394 (6%)

Query: 148  SSSEVSADNVQSSYPQSANHLDYSSKPFDFASSVGKYGLSHNSSVPTHCLLHRKKKLDTR 207
            S S  S+DN  SS   S+N  D SS   D ++S      S +S+       +     D+ 
Sbjct: 924  SESSNSSDNSNSS--DSSNSSD-SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS 980

Query: 208  KSEKKLESCKLTKELSLANLIHDMSRDSCESQPSVRLSSTDSLESLLSKNLDADLLRPHA 267
             S    +S   +          D S  S  S  S    S+DS +S  S + D+      +
Sbjct: 981  NSSDSSDSSDSS----------DSSDSSDSSNSSDSSDSSDSSDS--SNSSDSSNSSDSS 1028

Query: 268  SECISKDDSAFKEIPDLKTIIIKGTTPNNSLYIQNNSLSDFQNIPVQDSLGSSNNPLYLT 327
            +   S D S   +  D        ++ ++     +NS     +    DS  SS++     
Sbjct: 1029 NSSDSSDSSDSSDSSD--------SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080

Query: 328  SSLENMTVDNLNASKETEVGNVSLVEQSAKNHTFKNDNLQFSQCESPSLTELFQEHKENN 387
            SS  + + D+ N+S  ++  + S    S+ +    + +   +  +S   ++       +N
Sbjct: 1081 SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 1140

Query: 388  ISQCFTLSDLCNQSSASFTDLSLGSFPLSQLANRCQSSPGISELTGSLSSLAFHKASPTR 447
             S     S+  + S +S +  S  S   S  ++   SS   S+ + S  S     +S + 
Sbjct: 1141 SSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSS-NSSDSSDSSDSSDSSDSSDSS 1199

Query: 448  DLENLSLSELIAETIDVDNSQIKKESFEVSLSEVRSPGIDSNIDLSVLIKNPDFVPKPVV 507
            D  + S S   +++ D  +S    +S + S S   S   DS+ D S    + D       
Sbjct: 1200 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSS-DSSDSSNSSDSSDSSDS 1258

Query: 508  DPSIAPSSRTKVLSSKLGKNSNFAKDNKKNNKGS 541
              S + S+      SK G  +N   D+  +++GS
Sbjct: 1259 SDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGS 1292



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 80/345 (23%), Positives = 128/345 (37%), Gaps = 26/345 (7%)

Query: 148  SSSEVSADNVQSSYPQSANHLDYSSKPFDFASSVGKYGLSHNSSVPTHCLLHRKKKLDTR 207
            S S  S+D+   S   S+N  D S+      SS      S NSS             D+ 
Sbjct: 839  SDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD-----SSNSS-------------DSS 880

Query: 208  KSEKKLESCKLTKELSLANLIHDMSRDSCESQPSVRLS-STDSLESLLSKNLDADLLRPH 266
             S    ES   +     +N     S DS  S  S   S S+DS ES  S + D       
Sbjct: 881  DSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES--SNSSDNSNSSDS 938

Query: 267  ASECISKDDSAFKEIPDLKTIIIKGTTPNNSLYIQNNSLSDFQNIPVQDSLGSSNNPLYL 326
            ++   S D S      D         + N+S    +NS     +    DS  SS++    
Sbjct: 939  SNSSDSSDSSDSSNSSDSSN---SSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS 995

Query: 327  TSSLENMTVDNLNASKETEVGNVSLVEQSAKNHTFKNDNLQFSQCESPSLTELFQEHKEN 386
             SS  + + D+ ++S  ++  N S    S+ +    + +      +S   ++       +
Sbjct: 996  DSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1055

Query: 387  NISQCFTLSDLCNQSSASFTDLSLGSFPLSQLANRCQSSPG--ISELTGSLSSLAFHKAS 444
            N S     SD  + S +S +  S  S   S  ++   SS     S+ + S  S     +S
Sbjct: 1056 NSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1115

Query: 445  PTRDLENLSLSELIAETIDVDNSQIKKESFEVSLSEVRSPGIDSN 489
             + D  N S S   +++ D  +S    +S + S S   S   DS+
Sbjct: 1116 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSS 1160


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 83/350 (23%), Positives = 133/350 (38%), Gaps = 65/350 (18%)

Query: 48   PSVEPVEEYDY-EDLKESSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVL 106
            PS+ P +E D  + LK+ S S  +   S  D A+L S +  + E     + DE   +   
Sbjct: 1378 PSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQ 1437

Query: 107  KNKFDVQKALSGVLEQDRVQSLKDKNEATVSTGKIAKGVLFSSSEVSADNVQSSYPQSAN 166
             ++   ++      +Q++ QSL +  E T+S  +I +           D+ Q   P S +
Sbjct: 1438 PHEVSPEQPK----DQEKTQSLSETLEITISEEEIKESQEERKDTFKKDS-QQDIPSSKD 1492

Query: 167  HLDYSS---------KPFDFASSVGKYGLSHNSSVPTHCLLHRKKKLDTRKS---EKKLE 214
            H + S          +P+D   SV +   S NS VP      RK++     S   E K E
Sbjct: 1493 HKEKSEFVDDITTRREPYD---SVEESSESENSPVP-----QRKRRTSVGSSSSDEYKQE 1544

Query: 215  SCKLTKELS--LANLIHDMSRDS----CESQPSVR------LSSTDS------------- 249
              + + E    +   I +MS D      E    +R       SST+S             
Sbjct: 1545 DSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKIT 1604

Query: 250  ------LESLLSKNLDADLLRPHASECISKDDSAFKEIPDLKTIIIKGTTPNNSLYIQNN 303
                  L    S ++D D  R H+     +DD AF E P+LK    K       +     
Sbjct: 1605 AGKHRRLTRKSSTSIDEDAGRRHSWH--DEDDEAFDESPELKYRETKSQESEELVVTGGG 1662

Query: 304  SLSDFQNIPVQDSLGSSNNPLYLTSSLENMTVDNLNASKETEVGNVSLVE 353
             L  F+ I +  ++       Y   S +  T  +L   +E E+   SL +
Sbjct: 1663 GLRRFKTIELNSTIADK----YSAESSQKKT--SLYFDEEPELEMESLTD 1706


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 83/350 (23%), Positives = 133/350 (38%), Gaps = 65/350 (18%)

Query: 48   PSVEPVEEYDY-EDLKESSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVL 106
            PS+ P +E D  + LK+ S S  +   S  D A+L S +  + E     + DE   +   
Sbjct: 1378 PSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQ 1437

Query: 107  KNKFDVQKALSGVLEQDRVQSLKDKNEATVSTGKIAKGVLFSSSEVSADNVQSSYPQSAN 166
             ++   ++      +Q++ QSL +  E T+S  +I +           D+ Q   P S +
Sbjct: 1438 PHEVSPEQPK----DQEKTQSLSETLEITISEEEIKESQEERKDTFKKDS-QQDIPSSKD 1492

Query: 167  HLDYSS---------KPFDFASSVGKYGLSHNSSVPTHCLLHRKKKLDTRKS---EKKLE 214
            H + S          +P+D   SV +   S NS VP      RK++     S   E K E
Sbjct: 1493 HKEKSEFVDDITTRREPYD---SVEESSESENSPVP-----QRKRRTSVGSSSSDEYKQE 1544

Query: 215  SCKLTKELS--LANLIHDMSRDS----CESQPSVR------LSSTDS------------- 249
              + + E    +   I +MS D      E    +R       SST+S             
Sbjct: 1545 DSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKIT 1604

Query: 250  ------LESLLSKNLDADLLRPHASECISKDDSAFKEIPDLKTIIIKGTTPNNSLYIQNN 303
                  L    S ++D D  R H+     +DD AF E P+LK    K       +     
Sbjct: 1605 AGKHRRLTRKSSTSIDEDAGRRHSWH--DEDDEAFDESPELKYRETKSQESEELVVTGGG 1662

Query: 304  SLSDFQNIPVQDSLGSSNNPLYLTSSLENMTVDNLNASKETEVGNVSLVE 353
             L  F+ I +  ++       Y   S +  T  +L   +E E+   SL +
Sbjct: 1663 GLRRFKTIELNSTIADK----YSAESSQKKT--SLYFDEEPELEMESLTD 1706


>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
          Length = 1417

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 68/343 (19%), Positives = 143/343 (41%), Gaps = 24/343 (6%)

Query: 57  DYEDLKESSNSVSNHQLSGFDQARLYSCLD-HMREVLGDAVPDEILIEAVLKNKFDVQKA 115
           + E LKE    +     +G ++ R+ +  +  +   L ++    + +E+ L+NK ++ + 
Sbjct: 415 ELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILR- 473

Query: 116 LSGVLEQDRVQSLKDKNEATVSTGKIAKGVLFSSSEVSADNVQ-SSYPQSANHLDYSSKP 174
                  D+   + +  E  V      + +     E+ +  V+  S  +  + L    + 
Sbjct: 474 -------DKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQLPLKREL 526

Query: 175 FDFASSVGKYGLSHNSSVPTHCL--LHRKK----KLDTRKSEKKLESCKLTKELSLANLI 228
           F F S + KY +S  S+    C+      K    +L  + + K+ E  KL   L+ AN +
Sbjct: 527 FGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLT-ANQL 585

Query: 229 HDMSRDSCESQPSVRLSSTDSLESLLSKNLDADLLRPHASECISKDDSAFKE-----IPD 283
                   +SQ S +LSS ++    L  +  A+ ++      ++K     ++     I +
Sbjct: 586 SQSLITCNDSQESSKLSSLETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQRLVTGIEE 645

Query: 284 LKTIIIKGTTPNNSLYI-QNNSLSDFQNIPVQDSLGSSNNPLYLTSSLENMTVDNLNASK 342
           L+T +I+    N+ L +   +  S FQ I  ++ L  ++N   L S +       L   K
Sbjct: 646 LRTKLIQIEAENSDLKVNMAHRTSQFQLIQ-EELLEKASNSSKLESEMTKKCSQLLTLEK 704

Query: 343 ETEVGNVSLVEQSAKNHTFKNDNLQFSQCESPSLTELFQEHKE 385
           + E   V+    +AKN   + + ++ ++      T +  EH++
Sbjct: 705 QLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEK 747


>gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens]
          Length = 861

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 57/251 (22%), Positives = 94/251 (37%), Gaps = 39/251 (15%)

Query: 199 HRKKKLDTRKSEKKLESCKLTKELSLANLIHDMSRDSCESQP-SVRLSSTDSLESLLSKN 257
           H+  K  T KS K        K+LS  +   D S  + + +P S   SS+ S  S L  +
Sbjct: 616 HKPSKTKTSKSSK-------VKDLSTRS---DESPSNKKRKPQSSTSSSSSSSSSSLQTS 665

Query: 258 LDADLLRPHASECISKDDSAFKEIPDLKTIIIKGTTPNNSLYIQN--NSLSDFQN----- 310
           L + L  PH   C+    SA            +   P NSL + N  N +S         
Sbjct: 666 LSSPLSGPHKKNCVLNASSALNSY--------QAAPPYNSLSVHNSNNGVSPLSAKLEPS 717

Query: 311 ------------IPVQDSLGSSNNPLYLTSSLENMTVDNLNASKETEVGNVSLVEQSAKN 358
                       +    ++G S++   L+     +   +L+ +    V ++ L    ++ 
Sbjct: 718 GRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEG 777

Query: 359 HTFKNDNLQFSQCESPSLTELFQEHKENNISQCFTLSDLCNQSSASFTDLSLGSFPLSQL 418
              KN +     C+   +  +   HK+N  S    + D  N +S+     +  S  LSQ 
Sbjct: 778 KKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKN-SSLALSQS 836

Query: 419 ANRCQSSPGIS 429
           +    SSPG S
Sbjct: 837 SPSSISSPGHS 847



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 65/275 (23%), Positives = 103/275 (37%), Gaps = 35/275 (12%)

Query: 265 PHASECISKDDSAFKEIPDLKTI--IIKGTT--PNNSLYIQNNSLSDFQNIPVQDSLGSS 320
           PH +  +S  DS FK    +  I  +I   +  P+ +   +++ + D      +      
Sbjct: 585 PHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKK 644

Query: 321 NNPLYLTSSLENMTVDNLNASKETEVGNVSLVEQSAKNHTFKNDNLQFSQCESPSLTELF 380
             P   TSS  + +  +L  S  + +          KN      +   S   +P    L 
Sbjct: 645 RKPQSSTSSSSSSSSSSLQTSLSSPLSG-----PHKKNCVLNASSALNSYQAAPPYNSLS 699

Query: 381 QEHKENNISQCFTLSDLCNQSSASFTDLSLGSFPLSQLANRCQSSPGISELTGSLSSLAF 440
             +  N +S    LS     S    T L  G   + +       S     L  S+ SLA 
Sbjct: 700 VHNSNNGVSP---LSAKLEPSGR--TSLPGGPADIVRQVGAVGGSSDSCPL--SVPSLAL 752

Query: 441 HKASPTRDLENLSLSELIAETIDVDNSQIKKESFEVSLSEV----RSPGIDSNIDLSVLI 496
           H      DL   S + + +  +  D S+ KK     S S+     + PG++S     V  
Sbjct: 753 HAG----DLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNS-----VHK 803

Query: 497 KNPDFVPKPVVDPSIAPSSRTKVLSSKLGKNSNFA 531
           KNP  +  PV DP  + SSR      ++GKNS+ A
Sbjct: 804 KNPPSLLAPVPDPVNSTSSR------QVGKNSSLA 832


>gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens]
          Length = 738

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 57/251 (22%), Positives = 94/251 (37%), Gaps = 39/251 (15%)

Query: 199 HRKKKLDTRKSEKKLESCKLTKELSLANLIHDMSRDSCESQP-SVRLSSTDSLESLLSKN 257
           H+  K  T KS K        K+LS  +   D S  + + +P S   SS+ S  S L  +
Sbjct: 492 HKPSKTKTSKSSK-------VKDLSTRS---DESPSNKKRKPQSSTSSSSSSSSSSLQTS 541

Query: 258 LDADLLRPHASECISKDDSAFKEIPDLKTIIIKGTTPNNSLYIQN--NSLSDFQN----- 310
           L + L  PH   C+    SA            +   P NSL + N  N +S         
Sbjct: 542 LSSPLSGPHKKNCVLNASSALNSY--------QAAPPYNSLSVHNSNNGVSPLSAKLEPS 593

Query: 311 ------------IPVQDSLGSSNNPLYLTSSLENMTVDNLNASKETEVGNVSLVEQSAKN 358
                       +    ++G S++   L+     +   +L+ +    V ++ L    ++ 
Sbjct: 594 GRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKSEG 653

Query: 359 HTFKNDNLQFSQCESPSLTELFQEHKENNISQCFTLSDLCNQSSASFTDLSLGSFPLSQL 418
              KN +     C+   +  +   HK+N  S    + D  N +S+     +  S  LSQ 
Sbjct: 654 KKRKNSSSSSKACKITKMPGMNSVHKKNPPSLLAPVPDPVNSTSSRQVGKN-SSLALSQS 712

Query: 419 ANRCQSSPGIS 429
           +    SSPG S
Sbjct: 713 SPSSISSPGHS 723



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 65/275 (23%), Positives = 103/275 (37%), Gaps = 35/275 (12%)

Query: 265 PHASECISKDDSAFKEIPDLKTI--IIKGTT--PNNSLYIQNNSLSDFQNIPVQDSLGSS 320
           PH +  +S  DS FK    +  I  +I   +  P+ +   +++ + D      +      
Sbjct: 461 PHVAATLSIMDSTFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKK 520

Query: 321 NNPLYLTSSLENMTVDNLNASKETEVGNVSLVEQSAKNHTFKNDNLQFSQCESPSLTELF 380
             P   TSS  + +  +L  S  + +          KN      +   S   +P    L 
Sbjct: 521 RKPQSSTSSSSSSSSSSLQTSLSSPLSG-----PHKKNCVLNASSALNSYQAAPPYNSLS 575

Query: 381 QEHKENNISQCFTLSDLCNQSSASFTDLSLGSFPLSQLANRCQSSPGISELTGSLSSLAF 440
             +  N +S    LS     S    T L  G   + +       S     L  S+ SLA 
Sbjct: 576 VHNSNNGVSP---LSAKLEPSGR--TSLPGGPADIVRQVGAVGGSSDSCPL--SVPSLAL 628

Query: 441 HKASPTRDLENLSLSELIAETIDVDNSQIKKESFEVSLSEV----RSPGIDSNIDLSVLI 496
           H      DL   S + + +  +  D S+ KK     S S+     + PG++S     V  
Sbjct: 629 HAG----DLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNS-----VHK 679

Query: 497 KNPDFVPKPVVDPSIAPSSRTKVLSSKLGKNSNFA 531
           KNP  +  PV DP  + SSR      ++GKNS+ A
Sbjct: 680 KNPPSLLAPVPDPVNSTSSR------QVGKNSSLA 708


>gi|153251840 zinc finger protein 839 [Homo sapiens]
          Length = 927

 Score = 35.4 bits (80), Expect = 0.16
 Identities = 37/126 (29%), Positives = 51/126 (40%), Gaps = 12/126 (9%)

Query: 124 RVQSLKDKNEATVSTGKIAKGVLFSSSEVSADNVQSSYPQSANH--LDYSS---KPFDFA 178
           R    K K+   + T  +A G L  S + S   V+    Q   H   D SS   +P  F 
Sbjct: 255 RPPKYKAKDYKFIKTEDLADGHLSDSDDYSELCVEEDEDQRERHALFDLSSCSLRPKSFK 314

Query: 179 ------SSVGKYGLSHNSSV-PTHCLLHRKKKLDTRKSEKKLESCKLTKELSLANLIHDM 231
                 S +GK GL+ +  + P H  L  +  L  + S   L  C   + LSL +L   M
Sbjct: 315 CQTCEKSYIGKGGLARHFKLNPGHGQLDPEMVLSEKASGSTLRGCTEERTLSLTSLGLSM 374

Query: 232 SRDSCE 237
             D CE
Sbjct: 375 PADPCE 380


>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo
           sapiens]
          Length = 823

 Score = 33.1 bits (74), Expect = 0.80
 Identities = 27/110 (24%), Positives = 51/110 (46%), Gaps = 3/110 (2%)

Query: 197 LLHRKKKLDTRKSEKKLESCKLTKELSLANLIHDMSRDSCESQPSVRLSSTDSLESLLSK 256
           +L++K + +  + EK+ +     K+L       +M   +  + P+    + + ++ L+ +
Sbjct: 454 MLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDE 513

Query: 257 N--LDADLLRPHASECISKDDSAFKEIPDLKTI-IIKGTTPNNSLYIQNN 303
           N  L AD+       C  K+D+  KE   LK I I+K T      YI+ N
Sbjct: 514 NCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLN 563


>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo
           sapiens]
          Length = 823

 Score = 33.1 bits (74), Expect = 0.80
 Identities = 27/110 (24%), Positives = 51/110 (46%), Gaps = 3/110 (2%)

Query: 197 LLHRKKKLDTRKSEKKLESCKLTKELSLANLIHDMSRDSCESQPSVRLSSTDSLESLLSK 256
           +L++K + +  + EK+ +     K+L       +M   +  + P+    + + ++ L+ +
Sbjct: 454 MLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDE 513

Query: 257 N--LDADLLRPHASECISKDDSAFKEIPDLKTI-IIKGTTPNNSLYIQNN 303
           N  L AD+       C  K+D+  KE   LK I I+K T      YI+ N
Sbjct: 514 NCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLN 563


>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
           sapiens]
          Length = 823

 Score = 33.1 bits (74), Expect = 0.80
 Identities = 27/110 (24%), Positives = 51/110 (46%), Gaps = 3/110 (2%)

Query: 197 LLHRKKKLDTRKSEKKLESCKLTKELSLANLIHDMSRDSCESQPSVRLSSTDSLESLLSK 256
           +L++K + +  + EK+ +     K+L       +M   +  + P+    + + ++ L+ +
Sbjct: 454 MLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDE 513

Query: 257 N--LDADLLRPHASECISKDDSAFKEIPDLKTI-IIKGTTPNNSLYIQNN 303
           N  L AD+       C  K+D+  KE   LK I I+K T      YI+ N
Sbjct: 514 NCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLN 563


>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
           sapiens]
          Length = 823

 Score = 33.1 bits (74), Expect = 0.80
 Identities = 27/110 (24%), Positives = 51/110 (46%), Gaps = 3/110 (2%)

Query: 197 LLHRKKKLDTRKSEKKLESCKLTKELSLANLIHDMSRDSCESQPSVRLSSTDSLESLLSK 256
           +L++K + +  + EK+ +     K+L       +M   +  + P+    + + ++ L+ +
Sbjct: 454 MLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDE 513

Query: 257 N--LDADLLRPHASECISKDDSAFKEIPDLKTI-IIKGTTPNNSLYIQNN 303
           N  L AD+       C  K+D+  KE   LK I I+K T      YI+ N
Sbjct: 514 NCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLN 563


>gi|30795196 LIM homeobox protein 2 [Homo sapiens]
          Length = 406

 Score = 32.7 bits (73), Expect = 1.0
 Identities = 27/124 (21%), Positives = 52/124 (41%), Gaps = 1/124 (0%)

Query: 398 CNQSSASFTDLSLGSFPLSQLANRCQSSPGISELTGSLSSLAFHKASPTRDLENLSLSEL 457
           CN++ A   D     +P SQ   R ++S    +L    S  A +     +DL+ L+    
Sbjct: 246 CNENDAEHLDRDQ-PYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTG 304

Query: 458 IAETIDVDNSQIKKESFEVSLSEVRSPGIDSNIDLSVLIKNPDFVPKPVVDPSIAPSSRT 517
           + + +     Q  +  F  +L    + G+D + D ++    P      + + S++PSS  
Sbjct: 305 LTKRVLQVWFQNARAKFRRNLLRQENTGVDKSTDAALQTGTPSGPASELSNASLSPSSTP 364

Query: 518 KVLS 521
             L+
Sbjct: 365 TTLT 368


>gi|24430212 interleukin 23 receptor precursor [Homo sapiens]
          Length = 629

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 30/113 (26%), Positives = 44/113 (38%), Gaps = 17/113 (15%)

Query: 274 DDSAFKEIPDLKTII---IKGTTPNNSLYIQNNSLSDFQNIPVQDSLGSSNNPLYLTSSL 330
           D++    IPDL T     I    P  S    NN ++     P  DSL S NNP       
Sbjct: 470 DNTTVVYIPDLNTGYKPQISNFLPEGSHLSNNNEITSLTLKPPVDSLDSGNNPRLQKHPN 529

Query: 331 ENMTVDNLNASKET-EVGNVSLVEQSAKNHTFKNDNLQFSQCESPSLTELFQE 382
              +V ++N+   T  +G +SL+             L   +C SP +    +E
Sbjct: 530 FAFSVSSVNSLSNTIFLGELSLI-------------LNQGECSSPDIQNSVEE 569


>gi|46359075 zinc finger protein 423 [Homo sapiens]
          Length = 1284

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 19/42 (45%), Positives = 24/42 (57%), Gaps = 2/42 (4%)

Query: 171 SSKPFDFASSVGKYGLSHNSSVPTHCLLHRKKKLDTRKSEKK 212
           SSKPF    +V K G S  SS+ +H   H+K K    KSEK+
Sbjct: 218 SSKPFK--CTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKE 257


>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
          Length = 1317

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 37/183 (20%), Positives = 77/183 (42%), Gaps = 6/183 (3%)

Query: 394  LSDLCNQSSASFTDLSLGSFPLSQLANRCQSSPGISELTGSLSSLAFHKASPTRDLENLS 453
            L+ L  + SA     +LG     Q       + G  E +G  +SL   + +  +D E L 
Sbjct: 1009 LARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQERLE 1068

Query: 454  --LSELIAETIDVDNSQIKKESFEVSLSEVRSPGIDSNIDLSVLIKNPDFVPKPVVDPSI 511
              + +L  +  +VD   ++K+       +V S  +  + + S L+   D      ++  +
Sbjct: 1069 YEIQQLKQKIYEVDG--VQKDHHGTLEGKVASSSLPVSAEKSHLVPLMDARINAYIEEEV 1126

Query: 512  APSSRT--KVLSSKLGKNSNFAKDNKKNNKGSLTRKPPFSLSWTKALAARPSAFASTLCL 569
                +   +V+S     +++  KDN+K + G++ RK  +    +++L A P      + +
Sbjct: 1127 QRRLQDLHRVISEGCSTSADTMKDNEKLHNGTIQRKLKYERMVSRSLGANPDDLKDPIKI 1186

Query: 570  RYP 572
              P
Sbjct: 1187 SIP 1189


>gi|170016069 zinc finger, CCHC domain containing 2 [Homo sapiens]
          Length = 1178

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 10/141 (7%)

Query: 251 ESLLSKNLDADLLRPHASECISKDDSAFKEIPDLKTIIIKGTTPNNSLYIQNNSLSDFQN 310
           + L S+  D  +LR      + +++   +  PDL+ I+ +  + ++  ++Q+  +  F  
Sbjct: 403 KELSSETFDKTILRALNQGSLKREE---RRHPDLEPILRQLFSSSSQAFLQSQKVHSFFQ 459

Query: 311 IPVQDSLGSSNN---PLYLTSSLENMTVDNLNA-SKETEVGNVSLVEQSAKNHTFKNDNL 366
               DSL S NN    L  +  LE++  D+  A S+E +V   +++    K HT K+  +
Sbjct: 460 SISSDSLHSINNLQSSLKTSKILEHLKEDSSEASSQEEDVLQHAIIH---KKHTGKSPIV 516

Query: 367 QFSQCESPSLTELFQEHKENN 387
                    L  L  ++ E N
Sbjct: 517 NNIGTSCSPLDGLTMQYSEQN 537


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 61/299 (20%), Positives = 114/299 (38%), Gaps = 35/299 (11%)

Query: 197 LLHRKKKLDTRKSEKKLESCKL----TKELSLANLIHDMSRDSCESQPSVRLSSTDSLES 252
           LL  K  L+ +    +  S KL     + L L   +HDM  +        R      +E 
Sbjct: 356 LLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEME--------RDMDRKKIEE 407

Query: 253 LLSKNLDADLLRPHASECISKDDSAFK--EIPDLKTIIIKGTTPNNSLYIQNNSLSDFQN 310
           L+ +N+  ++ +       S D+S     E+  +         P  SL  + N L+  + 
Sbjct: 408 LMEENMTLEMAQKQ-----SMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRL 462

Query: 311 IPVQ---DSLGSSNNPLYLT--------SSLENMTVDNLNASKETEVGNVSLVE--QSAK 357
           + ++    SL  +   L  T        S +  M  +N   SK+ E+    +V+  QS +
Sbjct: 463 LKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQ 522

Query: 358 NHTFKNDNLQFSQCESPSLTELFQEHKENNISQCFTLSDLCNQSSASFTDLSLGSFPLSQ 417
           N    + +L   + +     E  +E+ E  I      ++  NQ+ +S    S  S     
Sbjct: 523 NCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARV 582

Query: 418 LANRCQSS---PGISELTGSLSSLAFHKASPTRDLENLSLSELIAETIDVDNSQIKKES 473
                ++      I E +  LS + F K    ++LE+       AE ++ +   ++KE+
Sbjct: 583 KDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKEN 641


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 61/299 (20%), Positives = 114/299 (38%), Gaps = 35/299 (11%)

Query: 197 LLHRKKKLDTRKSEKKLESCKL----TKELSLANLIHDMSRDSCESQPSVRLSSTDSLES 252
           LL  K  L+ +    +  S KL     + L L   +HDM  +        R      +E 
Sbjct: 356 LLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEME--------RDMDRKKIEE 407

Query: 253 LLSKNLDADLLRPHASECISKDDSAFK--EIPDLKTIIIKGTTPNNSLYIQNNSLSDFQN 310
           L+ +N+  ++ +       S D+S     E+  +         P  SL  + N L+  + 
Sbjct: 408 LMEENMTLEMAQKQ-----SMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRL 462

Query: 311 IPVQ---DSLGSSNNPLYLT--------SSLENMTVDNLNASKETEVGNVSLVE--QSAK 357
           + ++    SL  +   L  T        S +  M  +N   SK+ E+    +V+  QS +
Sbjct: 463 LKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQ 522

Query: 358 NHTFKNDNLQFSQCESPSLTELFQEHKENNISQCFTLSDLCNQSSASFTDLSLGSFPLSQ 417
           N    + +L   + +     E  +E+ E  I      ++  NQ+ +S    S  S     
Sbjct: 523 NCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARV 582

Query: 418 LANRCQSS---PGISELTGSLSSLAFHKASPTRDLENLSLSELIAETIDVDNSQIKKES 473
                ++      I E +  LS + F K    ++LE+       AE ++ +   ++KE+
Sbjct: 583 KDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKEN 641


>gi|38327034 ubiquitination factor E4B isoform 2 [Homo sapiens]
          Length = 1173

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 11/75 (14%)

Query: 416 SQLANRCQSSPGISELTGSLSSLAFHKASPTRDLENLSLSELIAETIDVDNSQIKKESFE 475
           S +A+R QSS G+S L+          +SP+  LE  S S   ++++D+D    +K   +
Sbjct: 70  SGVAHRSQSSEGVSSLS----------SSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQ 119

Query: 476 VSL-SEVRSPGIDSN 489
           V + S + +  +D N
Sbjct: 120 VDVDSGIENMEVDEN 134


>gi|157739864 ubiquitination factor E4B isoform 1 [Homo sapiens]
          Length = 1302

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 11/75 (14%)

Query: 416 SQLANRCQSSPGISELTGSLSSLAFHKASPTRDLENLSLSELIAETIDVDNSQIKKESFE 475
           S +A+R QSS G+S L+          +SP+  LE  S S   ++++D+D    +K   +
Sbjct: 70  SGVAHRSQSSEGVSSLS----------SSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQ 119

Query: 476 VSL-SEVRSPGIDSN 489
           V + S + +  +D N
Sbjct: 120 VDVDSGIENMEVDEN 134


>gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]
          Length = 1884

 Score = 31.6 bits (70), Expect = 2.3
 Identities = 60/265 (22%), Positives = 104/265 (39%), Gaps = 29/265 (10%)

Query: 150  SEVSADNVQSSY---PQSANHLDYSSKPFDFASSVGKYGLSHNSSVPTHCLLHRKKKLDT 206
            S +S +N++ +      S+N  +  S   +  SS+ + G S + ++      +R  KL+ 
Sbjct: 1024 STISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIG-SSDENIQAELGRNRGPKLNA 1082

Query: 207  RKSEKKLESCKLTKELSLANLIHDMSRDSCESQPSVRLSSTDSLESLLSKNLDADLLRPH 266
                  L+     + L  +N  H   +   E +  V+  +TD    L+S NL+  +   H
Sbjct: 1083 MLRLGVLQPEVYKQSLPGSNCKHPEIKKQ-EYEEVVQTVNTDFSPYLISDNLEQPMGSSH 1141

Query: 267  ASECISK------DDSAFKEIPDLKTIIIKGTTPNNSLYIQNNSLSDFQNIPVQDSL--G 318
            AS+  S+      DD   KE        IK ++   S  +Q   LS   +      L  G
Sbjct: 1142 ASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQG 1201

Query: 319  SSNNPLYLTSSLENMTVDN--LNASKETEVGNVSLVEQSAKNHTFKNDNLQFSQCESPSL 376
                   L SS EN++ ++  L   +    G V+ +   +  H             S   
Sbjct: 1202 YRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRH-------------STVA 1248

Query: 377  TELFQEHKENN-ISQCFTLSDLCNQ 400
            TE   ++ E N +S   +L+D  NQ
Sbjct: 1249 TECLSKNTEENLLSLKNSLNDCSNQ 1273


>gi|20302168 toll-like receptor 8 [Homo sapiens]
          Length = 1041

 Score = 31.6 bits (70), Expect = 2.3
 Identities = 53/191 (27%), Positives = 79/191 (41%), Gaps = 33/191 (17%)

Query: 278 FKEIPDLKTIIIKGTTPNNSLYIQNNSLSDFQNIPVQDSLGSSNNPLYLTSSLENMTVDN 337
           F+ +PD+  + +   +    L     S ++F  IP    L  +NN L           D 
Sbjct: 501 FENLPDIACLNLSANSNAQVL-----SGTEFSAIPHVKYLDLTNNRL-----------DF 544

Query: 338 LNASKETEVGNVSLVEQSAKNHTFK----NDNLQFSQCESPSLTELFQEHKENNISQCFT 393
            NAS  TE+ ++ +++ S  +H F+      +L+F Q    +L  L   H  NNI   +T
Sbjct: 545 DNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQ-NFTNLKVLNLSH--NNI---YT 598

Query: 394 LSDLCNQSSASFTDLSLGSFPLSQLANRCQSS-----PGISELTGSLSSLAFHKASPTRD 448
           L+D  N  S S  +L      L  L N   +       G+  LT    SL   K  P   
Sbjct: 599 LTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEA 658

Query: 449 LENL--SLSEL 457
             NL  SL+EL
Sbjct: 659 FLNLPASLTEL 669


>gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens]
          Length = 1816

 Score = 31.6 bits (70), Expect = 2.3
 Identities = 60/265 (22%), Positives = 104/265 (39%), Gaps = 29/265 (10%)

Query: 150  SEVSADNVQSSY---PQSANHLDYSSKPFDFASSVGKYGLSHNSSVPTHCLLHRKKKLDT 206
            S +S +N++ +      S+N  +  S   +  SS+ + G S + ++      +R  KL+ 
Sbjct: 977  STISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIG-SSDENIQAELGRNRGPKLNA 1035

Query: 207  RKSEKKLESCKLTKELSLANLIHDMSRDSCESQPSVRLSSTDSLESLLSKNLDADLLRPH 266
                  L+     + L  +N  H   +   E +  V+  +TD    L+S NL+  +   H
Sbjct: 1036 MLRLGVLQPEVYKQSLPGSNCKHPEIKKQ-EYEEVVQTVNTDFSPYLISDNLEQPMGSSH 1094

Query: 267  ASECISK------DDSAFKEIPDLKTIIIKGTTPNNSLYIQNNSLSDFQNIPVQDSL--G 318
            AS+  S+      DD   KE        IK ++   S  +Q   LS   +      L  G
Sbjct: 1095 ASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQG 1154

Query: 319  SSNNPLYLTSSLENMTVDN--LNASKETEVGNVSLVEQSAKNHTFKNDNLQFSQCESPSL 376
                   L SS EN++ ++  L   +    G V+ +   +  H             S   
Sbjct: 1155 YRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRH-------------STVA 1201

Query: 377  TELFQEHKENN-ISQCFTLSDLCNQ 400
            TE   ++ E N +S   +L+D  NQ
Sbjct: 1202 TECLSKNTEENLLSLKNSLNDCSNQ 1226


>gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]
          Length = 1863

 Score = 31.6 bits (70), Expect = 2.3
 Identities = 60/265 (22%), Positives = 104/265 (39%), Gaps = 29/265 (10%)

Query: 150  SEVSADNVQSSY---PQSANHLDYSSKPFDFASSVGKYGLSHNSSVPTHCLLHRKKKLDT 206
            S +S +N++ +      S+N  +  S   +  SS+ + G S + ++      +R  KL+ 
Sbjct: 1024 STISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIG-SSDENIQAELGRNRGPKLNA 1082

Query: 207  RKSEKKLESCKLTKELSLANLIHDMSRDSCESQPSVRLSSTDSLESLLSKNLDADLLRPH 266
                  L+     + L  +N  H   +   E +  V+  +TD    L+S NL+  +   H
Sbjct: 1083 MLRLGVLQPEVYKQSLPGSNCKHPEIKKQ-EYEEVVQTVNTDFSPYLISDNLEQPMGSSH 1141

Query: 267  ASECISK------DDSAFKEIPDLKTIIIKGTTPNNSLYIQNNSLSDFQNIPVQDSL--G 318
            AS+  S+      DD   KE        IK ++   S  +Q   LS   +      L  G
Sbjct: 1142 ASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQG 1201

Query: 319  SSNNPLYLTSSLENMTVDN--LNASKETEVGNVSLVEQSAKNHTFKNDNLQFSQCESPSL 376
                   L SS EN++ ++  L   +    G V+ +   +  H             S   
Sbjct: 1202 YRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRH-------------STVA 1248

Query: 377  TELFQEHKENN-ISQCFTLSDLCNQ 400
            TE   ++ E N +S   +L+D  NQ
Sbjct: 1249 TECLSKNTEENLLSLKNSLNDCSNQ 1273


>gi|110611228 utrophin [Homo sapiens]
          Length = 3433

 Score = 31.6 bits (70), Expect = 2.3
 Identities = 25/109 (22%), Positives = 49/109 (44%), Gaps = 5/109 (4%)

Query: 305  LSDFQNIPVQDSLGSSNNPLYLTSSLENMTVDNLNASKETE-VGNVSLVEQSAKNHTFKN 363
            LS    +P Q S+  +  P Y+    +    D+   ++  + + +++ V  SA     K 
Sbjct: 2810 LSTSVQLPWQRSISHNKVPYYINHQTQTTCWDHPKMTELFQSLADLNNVRFSAYRTAIKI 2869

Query: 364  DNLQFSQC----ESPSLTELFQEHKENNISQCFTLSDLCNQSSASFTDL 408
              LQ + C    E  +  E+F++HK N   Q  ++ D+ N  + ++  L
Sbjct: 2870 RRLQKALCLDLLELSTTNEIFKQHKLNQNDQLLSVPDVINCLTTTYDGL 2918


>gi|12056971 anaphase promoting complex subunit 1 [Homo sapiens]
          Length = 1944

 Score = 31.6 bits (70), Expect = 2.3
 Identities = 34/130 (26%), Positives = 53/130 (40%), Gaps = 28/130 (21%)

Query: 348 NVSLVEQSAKNHTFK-----NDNLQFSQCES-PSLTELFQEH-----------KENNISQ 390
           N+S   QS K H+       N N  F   E+ P + EL  +H           K +  S+
Sbjct: 370 NISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNIREKNSQASK 429

Query: 391 CFTLSDLCNQSSASFTDLSLGSFPLSQLANRC----QSSPGISELTGSLSSLAFHKASPT 446
            F  SDLC Q    F          SQL  RC    +S+     + GS++++    A+P 
Sbjct: 430 VFITSDLCGQKFLCF-------LVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPV 482

Query: 447 RDLENLSLSE 456
             ++ + + E
Sbjct: 483 EKIDTMLVLE 492


>gi|31559815 keratin 26 [Homo sapiens]
          Length = 468

 Score = 31.6 bits (70), Expect = 2.3
 Identities = 45/212 (21%), Positives = 92/212 (43%), Gaps = 25/212 (11%)

Query: 278 FKEIPDLKTIIIKGTTPNNSLYIQNNS---LSDFQNIPVQDSLGSSNNPLYLTSSLENMT 334
           F  I DLK  I   T  N S+ +QN++    +D   +  ++ L   ++    TS L  + 
Sbjct: 138 FSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVL 197

Query: 335 VDNLNASKETEVGNVSLVEQSA---KNHTFKNDNLQFSQCESPSLTELFQEHKENNISQC 391
            +    + + E+   +L E+     K+H  + + LQ++   + ++        E N +  
Sbjct: 198 DELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNV--------EMNATPG 249

Query: 392 FTLSDLCNQSSASFTDLSLGSFPLSQLANRCQSSPGISELTGSL-SSLAFHKASPTRDLE 450
             L+ L N   A + DL+          NR  +    +E + +L   ++ H+ + T    
Sbjct: 250 VDLTVLLNNMRAEYEDLA--------EQNRKDAEAWFNERSATLQQQISDHEGAATAARN 301

Query: 451 NLSLSELIAETIDVDNSQIK--KESFEVSLSE 480
            L+  +   +T++++   +   K S+E SL+E
Sbjct: 302 ELTELKRNLQTLEIELQSLMAVKHSYECSLAE 333


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,509,973
Number of Sequences: 37866
Number of extensions: 972994
Number of successful extensions: 2644
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 2604
Number of HSP's gapped (non-prelim): 79
length of query: 632
length of database: 18,247,518
effective HSP length: 108
effective length of query: 524
effective length of database: 14,157,990
effective search space: 7418786760
effective search space used: 7418786760
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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