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Search of human proteins with 222831660
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222831660 family with sequence similarity 171, member A2
[Homo sapiens]
(826 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222831660 family with sequence similarity 171, member A2 [Hom... 1663 0.0
gi|63025206 hypothetical protein LOC221061 [Homo sapiens] 566 e-161
gi|116875848 KIAA1946 [Homo sapiens] 279 7e-75
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ... 56 2e-07
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 50 7e-06
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 50 7e-06
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 50 1e-05
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 50 1e-05
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 49 2e-05
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 49 2e-05
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 49 2e-05
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 49 2e-05
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 49 2e-05
gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens] 47 7e-05
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 47 9e-05
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 46 2e-04
gi|110832843 TBP-associated factor 4 [Homo sapiens] 46 2e-04
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 46 2e-04
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 46 2e-04
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 46 2e-04
gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens] 46 2e-04
gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens] 46 2e-04
gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens] 46 2e-04
gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens] 46 2e-04
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 46 2e-04
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 46 2e-04
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 46 2e-04
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 46 2e-04
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 46 2e-04
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p... 45 2e-04
>gi|222831660 family with sequence similarity 171, member A2 [Homo
sapiens]
Length = 826
Score = 1663 bits (4307), Expect = 0.0
Identities = 826/826 (100%), Positives = 826/826 (100%)
Query: 1 MPPASGPSVLARLLPLLGLLLGSASRAPGKSPPEPPSPQEILIKVQVYVSGELVPLARAS 60
MPPASGPSVLARLLPLLGLLLGSASRAPGKSPPEPPSPQEILIKVQVYVSGELVPLARAS
Sbjct: 1 MPPASGPSVLARLLPLLGLLLGSASRAPGKSPPEPPSPQEILIKVQVYVSGELVPLARAS 60
Query: 61 VDVFGNRTLLAAGTTDSEGVATLPLSYRLGTWVLVTAARPGFLTNSVPWRVDKLPLYASV 120
VDVFGNRTLLAAGTTDSEGVATLPLSYRLGTWVLVTAARPGFLTNSVPWRVDKLPLYASV
Sbjct: 61 VDVFGNRTLLAAGTTDSEGVATLPLSYRLGTWVLVTAARPGFLTNSVPWRVDKLPLYASV 120
Query: 121 SLYLLPERPATLILYEDLVHILLGSPGARSQPLVQFQRRAARLPVSSTYSQLWASLTPAS 180
SLYLLPERPATLILYEDLVHILLGSPGARSQPLVQFQRRAARLPVSSTYSQLWASLTPAS
Sbjct: 121 SLYLLPERPATLILYEDLVHILLGSPGARSQPLVQFQRRAARLPVSSTYSQLWASLTPAS 180
Query: 181 TQQEMRAFPAFLGTEASSSGNGSWLELMPLTAVSVHLLTGNGTEVPLSGPIHLSLPVPSE 240
TQQEMRAFPAFLGTEASSSGNGSWLELMPLTAVSVHLLTGNGTEVPLSGPIHLSLPVPSE
Sbjct: 181 TQQEMRAFPAFLGTEASSSGNGSWLELMPLTAVSVHLLTGNGTEVPLSGPIHLSLPVPSE 240
Query: 241 TRALTVGTSIPAWRFDPKSGLWVRNGTGVIRKEGRQLYWTFVSPQLGYWVAAMASPTAGL 300
TRALTVGTSIPAWRFDPKSGLWVRNGTGVIRKEGRQLYWTFVSPQLGYWVAAMASPTAGL
Sbjct: 241 TRALTVGTSIPAWRFDPKSGLWVRNGTGVIRKEGRQLYWTFVSPQLGYWVAAMASPTAGL 300
Query: 301 VTITSGIQDIGTYHTIFLLTILAALALLVLILLCLLIYYCRRRCLKPRQQHRKLQLSGPS 360
VTITSGIQDIGTYHTIFLLTILAALALLVLILLCLLIYYCRRRCLKPRQQHRKLQLSGPS
Sbjct: 301 VTITSGIQDIGTYHTIFLLTILAALALLVLILLCLLIYYCRRRCLKPRQQHRKLQLSGPS 360
Query: 361 DGNKRDQATSMSQLHLICGGPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKP 420
DGNKRDQATSMSQLHLICGGPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKP
Sbjct: 361 DGNKRDQATSMSQLHLICGGPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKP 420
Query: 421 RSASRPAAEPSGARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPP 480
RSASRPAAEPSGARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPP
Sbjct: 421 RSASRPAAEPSGARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPP 480
Query: 481 FDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTL 540
FDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTL
Sbjct: 481 FDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTL 540
Query: 541 VIPAHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGG 600
VIPAHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGG
Sbjct: 541 VIPAHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGG 600
Query: 601 GEGWGAGRAAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPHPRAWFVSLDG 660
GEGWGAGRAAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPHPRAWFVSLDG
Sbjct: 601 GEGWGAGRAAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPHPRAWFVSLDG 660
Query: 661 RSNSQVRHSYIDLQAGGGARSTDASLDSGVDVHEARPARRRPAREERERAPPAAPPPPPA 720
RSNSQVRHSYIDLQAGGGARSTDASLDSGVDVHEARPARRRPAREERERAPPAAPPPPPA
Sbjct: 661 RSNSQVRHSYIDLQAGGGARSTDASLDSGVDVHEARPARRRPAREERERAPPAAPPPPPA 720
Query: 721 PPRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDEVAAPEGRAATVPRGRGRSRGDSSRS 780
PPRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDEVAAPEGRAATVPRGRGRSRGDSSRS
Sbjct: 721 PPRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDEVAAPEGRAATVPRGRGRSRGDSSRS 780
Query: 781 SASELRRDSLTSPEDELGAEVGDEAGDKKSPWQRREERPLMVFNVK 826
SASELRRDSLTSPEDELGAEVGDEAGDKKSPWQRREERPLMVFNVK
Sbjct: 781 SASELRRDSLTSPEDELGAEVGDEAGDKKSPWQRREERPLMVFNVK 826
>gi|63025206 hypothetical protein LOC221061 [Homo sapiens]
Length = 890
Score = 566 bits (1458), Expect = e-161
Identities = 359/906 (39%), Positives = 520/906 (57%), Gaps = 105/906 (11%)
Query: 10 LARLLPLLGLLLGS-ASRAPGKSPPEPPS-PQEILIKVQVYVSGELVPLARASVDVFGNR 67
++R LL LLG +A K+ EP + QE+ +KV + + P+A A +++F N+
Sbjct: 1 MSRSATLLLCLLGCHVWKAVTKTLREPGAGAQEVTLKVHISDASTHQPVADALIEIFTNQ 60
Query: 68 TLLAAGTTDSEGVATLPLSYRLGTWVLVTAARPGFLTNSVPWRVDKLPLYASVSLYLLPE 127
+A+GT+ ++GVA + Y+LG+ ++VTA++ ++ NS PW+ +LP+++S+SL LLPE
Sbjct: 61 ASIASGTSGTDGVAFIKFQYKLGSQLIVTASKHAYVPNSAPWKPIRLPVFSSLSLGLLPE 120
Query: 128 RPATLILYEDLVHILLGSPGARSQPLVQFQRRAARLPVSSTYSQLWASLTPASTQQEMRA 187
R ATL++YED+V I+ G GAR QP V FQRRA RLP +++YS L A LT AS+ E+ +
Sbjct: 121 RSATLMVYEDVVQIVSGFQGARPQPRVHFQRRALRLPENTSYSDLTAFLTAASSPSEVDS 180
Query: 188 FPAFLGTEASSSGNGSWLELMPLTAVSVHLLTGNGTEVPLSGPIHLSLPVPSETRALTVG 247
FP G + + +GN + +L P+TAVSVHLL+ NGT V + GPI++++P+ +++ +L
Sbjct: 181 FPYLRGLDGNGTGNSTRHDLTPVTAVSVHLLSSNGTPVLVDGPIYVTVPLATQS-SLRHN 239
Query: 248 TSIPAWRFDPKSGLWVRNGTGVIRKEGRQLYWTFVSPQLGYWVAAMASPTAGLVTITSGI 307
+ AWRFD K G W+++G G++ +EG QL WT+++PQLGYWVAAM+ P G V
Sbjct: 240 AYVAAWRFDQKLGTWLKSGLGLVHQEGSQLTWTYIAPQLGYWVAAMSPPIPGPVV----T 295
Query: 308 QDIGTYHTIFLLTILAALALLVLILLCLLIYYCRRRCLKPRQQHRKLQLSGPSDGNKRDQ 367
QDI TYHT+FLL IL +A ++L+LLCLL+YYCRR+CLKPRQ HRKLQL + +KRDQ
Sbjct: 296 QDITTYHTVFLLAILGGMAFILLVLLCLLLYYCRRKCLKPRQHHRKLQLPAGLESSKRDQ 355
Query: 368 ATSMSQLHLICG-------GPLEPAPSGDPEAP-----------------PPGPLHS--- 400
+TSMS ++L+ GPL G PEAP G LH+
Sbjct: 356 STSMSHINLLFSRRASEFPGPLSVTSHGRPEAPGTKELMSGVHLEMMSPGGEGDLHTPML 415
Query: 401 --AFSSSRDLASSRDDFFRTKPRSASRPAAE---PSGARGG------ESAGLKGARSAEG 449
++S+S++ SSR++ K S+ + + PSG G E LK +S E
Sbjct: 416 KLSYSTSQEF-SSREELLSCKEEDKSQISFDNLTPSGTLGKDYHKSVEVFPLKARKSMER 474
Query: 450 PGGLEPGLEEH-----------------RRGPSGAAAFL----HEPPSPPPPFDHYLGHK 488
G G +++ R GP+ + L H P+P P L
Sbjct: 475 EGYESSGNDDYRGSYNTVLSQPLFEKQDREGPASTGSKLTIQEHLYPAPSSPEKEQL--- 531
Query: 489 GAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVR 548
+ + + ++S+SVD L RP S + GQLI C S+D + D+VYR V+P LVIPAHY++
Sbjct: 532 --LDRRPTECMMSRSVDHLERPTSFPRPGQLICCSSVDQVNDSVYRKVLPALVIPAHYMK 589
Query: 549 LGGEAGAAG----------VGDEPAPPEGTAPGPARAFPQPDPQ-RPQMPGHSGPGGEGG 597
L G+ + E E + P A FP P Q +PQ +
Sbjct: 590 LPGDHSYVSQPLVVPADQQLEIERLQAELSNP-HAGIFPHPSSQIQPQPLSSQAISQQHL 648
Query: 598 GGGGEGWGAGRAAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELG---VKPHPRAW 654
G + + A +S S++IP N++ +AQ+N E+Q LTEK L+ELG PHPRAW
Sbjct: 649 QDAGTREWSPQNASMSESLSIPASLNDAALAQMNSEVQLLTEKALMELGGGKPLPHPRAW 708
Query: 655 FVSLDGRSNSQVRHSYIDLQAGGGARSTDASLDSGVDVHEARPARR------------RP 702
FVSLDGRSN+ VRHSYIDLQ G S DASLDSGVD++E + AR+ P
Sbjct: 709 FVSLDGRSNAHVRHSYIDLQRAGRNGSNDASLDSGVDMNEPKSARKGRGDALSLQQNYPP 768
Query: 703 AREERERAPPAAPPPPPAPPRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDEVAAPE-G 761
+E +++ P A P A +L +D E S SE T +C+PED++L LL+ + G
Sbjct: 769 VQEHQQKEPRA--PDSTAYTQLVYLDDVEQSGSECGTTVCTPEDSALRCLLEGSSRRSGG 826
Query: 762 RAATVPRGRGRSRGDS-SRSSASELRRDSLTSPEDELGAEVGDEAGDKKSPWQRREERPL 820
+ ++ R D+ S +AS +R S + E+E + D+ DKKSPWQ+REERPL
Sbjct: 827 QLPSLQEETTRRTADAPSEPAASPHQRRS--AHEEEEDDDDDDQGEDKKSPWQKREERPL 884
Query: 821 MVFNVK 826
M FN+K
Sbjct: 885 MAFNIK 890
>gi|116875848 KIAA1946 [Homo sapiens]
Length = 826
Score = 279 bits (714), Expect = 7e-75
Identities = 229/823 (27%), Positives = 381/823 (46%), Gaps = 86/823 (10%)
Query: 25 SRAPGKSPPEPPSPQEILIKVQVYVSGELVPLARASVDVFGNRTLLAAGTTDSEGVATLP 84
+ PG + ++KVQV L++A V+VF N T + T S G +
Sbjct: 67 TEVPGATSTLTVPVSVFMLKVQVNDIISRQYLSQAVVEVFVNYTKTNSTVTKSNGAVLIK 126
Query: 85 LSYRLGTWVLVTAARPGFLTNSVPWRVDKLPLYASVSLYLLPERPATLILYEDLVHILLG 144
+ Y+LG + + A + G++ +PW+ ++P+Y+SV+L L P+ A + L+ED V I
Sbjct: 127 VPYKLGLSLTIIAYKDGYVLTPLPWKTRRMPIYSSVTLSLFPQSQANIWLFEDTVLITGK 186
Query: 145 SPGARSQPLVQFQRRAARLPVSSTYSQLWASLTPASTQQEMRAFPAFLGTEASSSGNGSW 204
A+SQP VQF + +LP + S + LT ++ F G + G +
Sbjct: 187 LADAKSQPSVQFSKALIKLPDNHHISNVTGYLTVLQQFLKVDNFLHTTGITLNKPGFEN- 245
Query: 205 LELMPLTAVSVHLLTGNGTEVPLSGPIHLSLPVPSETRALTVGTSIPAWRFDPKSGLWVR 264
+EL PL A+ V + +G G E+ ++G I +SLP+ ++ G IPAW FD +G WV
Sbjct: 246 IELTPLAAICVKIYSG-GKELKVNGSIQVSLPL-LRLNDISAGDRIPAWTFDMNTGAWVN 303
Query: 265 NGTGVIRKEGRQLYWTFVSPQLGYWVAAMASPTAGLVTITSGIQDIGTYHTIFLLTILAA 324
+G G++++ L WT+ +P LGYW+AA T G I +DI YHT+FL IL
Sbjct: 304 HGRGMVKEHNNHLIWTYDAPHLGYWIAAPLPGTRG-SGINEDSKDITAYHTVFLTAILGG 362
Query: 325 LALLVLILLCLLIYYCRRRCLKPRQQHRKLQLSGPSDGNKRDQATSMSQLHLICGGPLEP 384
++V+ +L+ YCR +C P+++ R + + KRDQ TS + ++ I ++
Sbjct: 363 TIVIVIGFFAVLLCYCRDKCGTPQKRERNIT---KLEVLKRDQTTSTTHINHI--STVKV 417
Query: 385 APSGDPEAPPPGPLHSAFSSSR------------DLASSRDDFFRTKPRSASRPAAEPSG 432
A + ++ +S++S + + +RDD F+ S + +
Sbjct: 418 ALKAEDKSQLFNAKNSSYSPQKKEPSKAETEERVSMVKTRDD-FKIYNEDVSFLSVNQNN 476
Query: 433 ARGGESAGLKGARSAEGPGGLEPGL-------EEHRRGPSGAAAFLHEPPSPPPPFDHYL 485
+ L+ ++ P + L ++ +R +G P Y
Sbjct: 477 YSRNPTQSLEPNVGSKQPKHINNNLSSSLGDAQDEKRYLTGNEEAYGRSHIPEQLMHIY- 535
Query: 486 GHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAH 545
+ A +T D + A+ +L + GQL++ ++ + + +P + I +H
Sbjct: 536 -SQPIAILQTSDLFSTPEQLHTAKSATLPRKGQLVYGQLMEPVNRENFTQTLPKMPIHSH 594
Query: 546 YVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWG 605
A +E EG P++A W
Sbjct: 595 -------AQPPDAREEDIILEGQQSLPSQA--------------------------SDW- 620
Query: 606 AGRAAPVSGSVTIPVLFNES-TMAQLNGELQALTEKKLLELG---VKPHPRAWFVSLDGR 661
+ ++ + SV++P NE+ M + ELQ ++E+ LLEL PHPRAWFVSLDG+
Sbjct: 621 SRYSSSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKPSPHPRAWFVSLDGK 680
Query: 662 SNSQVRHSYIDLQAGGGARSTDASLDSGVDVHEARPARRRPAREERERAPPAAPPPPPAP 721
+QVRHS+IDL+ G +S D SLDSGVD++E +R+ ERE+ +
Sbjct: 681 PVAQVRHSFIDLKKGKRTQSNDTSLDSGVDMNELHSSRKL----EREKTFIKS----MHQ 732
Query: 722 PRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDEVAAPEGRAATVPRGRGRSRGDSSRSS 781
P++ ED + SSSES T +CSPED +L +LD G + + G +S+
Sbjct: 733 PKILYLEDLDLSSSESGTTVCSPEDPALRHILD------GGSGVIMEHPG-EESPGRKST 785
Query: 782 ASELRRDSLTSPEDELGAEVGDEAGDKKSPWQRREERPLMVFN 824
+ ++ TSP G + K + W++REERPL+ N
Sbjct: 786 VEDF--EANTSPTKRRGRPPLAKRDSKTNIWKKREERPLIPIN 826
>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor [Homo
sapiens]
Length = 1336
Score = 55.8 bits (133), Expect = 2e-07
Identities = 81/311 (26%), Positives = 109/311 (35%), Gaps = 65/311 (20%)
Query: 301 VTITSGIQDIGTYHTIFLLTILAALALLVLILLCLLIYYCRRRCLKPRQQHRKLQLSGPS 360
+ + S DI +F + ++A L++ L+Y+ R CL P HR L S
Sbjct: 833 IEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLVYWRLRHCLGPT--HRMDFLLAFS 890
Query: 361 DGNKRDQATSMSQLHLICGGPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKP 420
G ++ C P P+ P PPP PL S + A F +
Sbjct: 891 RG-----------MYSCCSAEAAPPPAKPP--PPPQPLPSPAYPAPRPAPGPAPFVPRER 937
Query: 421 RSASR-----PAAEPSGARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPP 475
S R A P GA G + G P GL GL E R P GAA PP
Sbjct: 938 ASVDRWRRTKGAGPPGGA--GLADGFHRYYGPIEPQGLGLGLGEARAAPRGAAGRPLSPP 995
Query: 476 SPPPPFDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRN 535
+ PP + P + + A PP+ G
Sbjct: 996 AAQPP-----------QKPPPSYFAIVRDKEPAEPPAGAFPG------------------ 1026
Query: 536 VMPTLVIPAHYVRLGGEAGAAGVGD---EPAPPEGTAPGPARAFPQPDPQRPQM--PGHS 590
P+ P A A VG A + + P PAR +P+ DP+ + PG
Sbjct: 1027 -FPSPPAPP-------AAAATAVGPPLCRLAFEDESPPAPAR-WPRSDPESQPLLGPGAG 1077
Query: 591 GPGGEGGGGGG 601
G GG GG GGG
Sbjct: 1078 GAGGTGGAGGG 1088
Score = 30.8 bits (68), Expect = 5.4
Identities = 20/46 (43%), Positives = 25/46 (54%), Gaps = 3/46 (6%)
Query: 689 GVDVHEARPARRRPAREERERAPPAA-PPPPPAPPRLALSEDTEPS 733
G+ + EAR A R A R +PPAA PP P P A+ D EP+
Sbjct: 974 GLGLGEARAAPRGAAG--RPLSPPAAQPPQKPPPSYFAIVRDKEPA 1017
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 50.4 bits (119), Expect = 7e-06
Identities = 73/253 (28%), Positives = 86/253 (33%), Gaps = 33/253 (13%)
Query: 379 GGPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGES 438
G P P P G P PPGP + + +A D+ + P G RG
Sbjct: 156 GTPGNPGPPGPP--GPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPG 213
Query: 439 -AGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPP--PPFDHYLGHKGAAEGKT 495
AG G + +G G EPG E GP G PP PP P D G G A +
Sbjct: 214 PAGAPGPQGFQGNPG-EPG-EPGVSGPMGPRG----PPGPPGKPGDDGEAGKPGKAGERG 267
Query: 496 PDFLLSQSVDQLARPPSL----------------GQAGQLIFCGSIDHLKDNVYRNVMPT 539
P Q P L G+AG G +N M
Sbjct: 268 PPG--PQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP 325
Query: 540 LVIPAHYVRLGGEAGAAGV-GDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGG 598
+P R G AGAAG G++ P PGP P P P PG G G G
Sbjct: 326 RGLPGERGRT-GPAGAAGARGNDGQPGPAGPPGPVG--PAGGPGFPGAPGAKGEAGPTGA 382
Query: 599 GGGEGWGAGRAAP 611
G EG R P
Sbjct: 383 RGPEGAQGPRGEP 395
Score = 47.4 bits (111), Expect = 6e-05
Identities = 72/248 (29%), Positives = 86/248 (34%), Gaps = 40/248 (16%)
Query: 385 APSGDPEAPPPGPLHSAFSSSRD--LASSRDDFFRTKPRSASRPAAE-PSGARGGES--- 438
AP E PPGP A D + + + A P + PSGA G +
Sbjct: 820 APGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTG 879
Query: 439 -AGLKGARSAEGPGGLE--PGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKT 495
G KGAR A+GP G PG R GP G+ PP PP P G KGA
Sbjct: 880 VTGPKGARGAQGPPGATGFPGAAG-RVGPPGSNGN-PGPPGPPGPSGKD-GPKGARGDSG 936
Query: 496 PDFLLSQ-SVDQLARPPS-------------------LGQAGQLIFCGSIDHLKDNVYRN 535
P + + A PP G AGQ G L
Sbjct: 937 PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVG----LPGQRGER 992
Query: 536 VMPTLVIPAHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGE 595
P L P+ G+ GA G + PP P P P +P R PG GP G
Sbjct: 993 GFPGLPGPSGEP---GKQGAPGASGDRGPPGPVGP-PGLTGPAGEPGREGSPGADGPPGR 1048
Query: 596 GGGGGGEG 603
G G +G
Sbjct: 1049 DGAAGVKG 1056
Score = 40.4 bits (93), Expect = 0.007
Identities = 65/239 (27%), Positives = 80/239 (33%), Gaps = 57/239 (23%)
Query: 380 GPL-EPAPSG----DPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRP--AAEPSG 432
GP+ P P+G E PPGP SA +R R + P + P A G
Sbjct: 789 GPIGPPGPAGANGEKGEVGPPGPAGSA--GARGAPGERGETGPPGPAGFAGPPGADGQPG 846
Query: 433 ARGGES-AGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGA- 490
A+G + AG KG A GP +GPSGA P P P G KGA
Sbjct: 847 AKGEQGEAGQKGDAGAPGP-----------QGPSGA-------PGPQGPTG-VTGPKGAR 887
Query: 491 -AEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRL 549
A+G + ++ P S G G P
Sbjct: 888 GAQGPPGATGFPGAAGRVGPPGSNGNPG-------------------------PPGPPGP 922
Query: 550 GGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAGR 608
G+ G G + PP G A P P P PG GP G G G +G R
Sbjct: 923 SGKDGPKGARGDSGPP-GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQR 980
Score = 37.4 bits (85), Expect = 0.057
Identities = 72/246 (29%), Positives = 80/246 (32%), Gaps = 49/246 (19%)
Query: 379 GGPLEPAPSGDP-EAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASR---------PAA 428
G P SG P E PGP+ R L R RT P A+ PA
Sbjct: 303 GAPGVKGESGSPGENGSPGPM-----GPRGLPGERG---RTGPAGAAGARGNDGQPGPAG 354
Query: 429 EPS--GARGGES-AGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYL 485
P G GG G GA+ GP G RGP GA EP +P P
Sbjct: 355 PPGPVGPAGGPGFPGAPGAKGEAGPTGA--------RGPEGAQGPRGEPGTPGSP----- 401
Query: 486 GHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAH 545
G GA+ D + P + G AG G+ P
Sbjct: 402 GPAGASGNPGTDGI----------PGAKGSAGAPGIAGAPGFPGPRGPPGPQGATG-PLG 450
Query: 546 YVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWG 605
GE G AG E P PGPA PQ P G G GE GG G G
Sbjct: 451 PKGQTGEPGIAGFKGEQGPK--GEPGPAG--PQGAPGPAGEEGKRGARGEPGGVGPIGPP 506
Query: 606 AGRAAP 611
R AP
Sbjct: 507 GERGAP 512
Score = 37.0 bits (84), Expect = 0.075
Identities = 67/233 (28%), Positives = 79/233 (33%), Gaps = 44/233 (18%)
Query: 386 PSGDPEAPPPG----PLHSAFSSSRDLASSRDDFFRTKPRSASRP-AAEPSGARGGESAG 440
P G PPG P + F LA + P + P A R GE G
Sbjct: 497 PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP-G 555
Query: 441 LKGARSAEG-PGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDFL 499
L GAR G PG P + + GPSGA E P PP G +GA
Sbjct: 556 LPGARGLTGRPGDAGP---QGKVGPSGAPG---EDGRPGPP-----GPQGAR-------- 596
Query: 500 LSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVG 559
+P +G G G + +P GE GAAG
Sbjct: 597 --------GQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGK----DGETGAAG-- 642
Query: 560 DEPAPPEGTAPGPARAFPQPDPQRPQ-MPGHSGPGGEGGGGGGEGWGAGRAAP 611
P P G A G P P Q +PG GP GEGG G +G AP
Sbjct: 643 --PPGPAGPA-GERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAP 692
Score = 35.0 bits (79), Expect = 0.28
Identities = 54/186 (29%), Positives = 58/186 (31%), Gaps = 59/186 (31%)
Query: 420 PRSASRPAAEPSGARGGESAGLKGARSAEGPGGL--EPGLEEHRRGPSGAAAFLHEPPSP 477
P PA E G RG G KG + A GP G EPG + GP G PP P
Sbjct: 121 PPGPQGPAGE-QGPRGDR--GDKGEKGAPGPRGRDGEPGTPGNP-GPPG-------PPGP 169
Query: 478 PPPFDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVM 537
P P P LG G D VM
Sbjct: 170 PGP------------------------------PGLGGNFAAQMAGGFDEKAGGAQLGVM 199
Query: 538 PTLVIPAHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGG 597
G G G P P APGP + F Q +P P PG SGP G G
Sbjct: 200 Q------------GPMGPMGPRGPPGP--AGAPGP-QGF-QGNPGEPGEPGVSGPMGPRG 243
Query: 598 GGGGEG 603
G G
Sbjct: 244 PPGPPG 249
Score = 35.0 bits (79), Expect = 0.28
Identities = 58/196 (29%), Positives = 68/196 (34%), Gaps = 49/196 (25%)
Query: 379 GGPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGES 438
G P P P G P P GP R + P S PA GARG +
Sbjct: 1065 GAPGAPGPPGSPG--PAGPTGKQ--------GDRGEAGAQGPMGPSGPA----GARGIQ- 1109
Query: 439 AGLKGARSAEGPGGLEPGLEEHRRGPSGAAAF--LHEPPSPPPPFDHYLGHKGAAEGKTP 496
G +G R +G G EPG RG G F L P PP P G +GA+ P
Sbjct: 1110 -GPQGPRGDKGEAG-EPG----ERGLKGHRGFTGLQGLPGPPGPS----GDQGASGPAGP 1159
Query: 497 DFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAA 556
P +G +G KD N +P + P GE G A
Sbjct: 1160 S-------GPRGPPGPVGPSG-----------KDGA--NGIPGPIGPPGPRGRSGETGPA 1199
Query: 557 GVGDEPAPPEGTAPGP 572
G P PP PGP
Sbjct: 1200 GPPGNPGPP--GPPGP 1213
Score = 32.7 bits (73), Expect = 1.4
Identities = 68/231 (29%), Positives = 80/231 (34%), Gaps = 39/231 (16%)
Query: 384 PAPSGDPEAP-PPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGESA--G 440
P +G+P P PPGP S +R D P A P + GE G
Sbjct: 908 PGSNGNPGPPGPPGP-----SGKDGPKGARGD--SGPPGRAGEPGLQGPAGPPGEKGEPG 960
Query: 441 LKGARSAEGPGGLEPGLEEHRR-----GPSGAAAFLHEP-PSPPPPFDHYLGHKGAAEGK 494
G AEGP G + GL R G G F P PS P G GA+ +
Sbjct: 961 DDGPSGAEGPPGPQ-GLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQ---GAPGASGDR 1016
Query: 495 TPDFLLSQSVDQLARPPSL-GQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEA 553
P + PP L G AG+ GS + P A GE
Sbjct: 1017 GPPGPVG--------PPGLTGPAGEPGREGSPG-------ADGPPGRDGAAGVKGDRGET 1061
Query: 554 GAAGVGDEPAPPEGTAPGPA-RAFPQPDPQRPQMPGHSGPGGEGGGGGGEG 603
GA G P PP +PGPA Q D G GP G G G +G
Sbjct: 1062 GAVGAPGAPGPP--GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQG 1110
Score = 32.0 bits (71), Expect = 2.4
Identities = 24/65 (36%), Positives = 28/65 (43%), Gaps = 6/65 (9%)
Query: 551 GEAGAAGV-GDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAGRA 609
G AG G GD E APGP +P PG+ GP G G G G G A
Sbjct: 126 GPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT-----PGNPGPPGPPGPPGPPGLGGNFA 180
Query: 610 APVSG 614
A ++G
Sbjct: 181 AQMAG 185
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 50.4 bits (119), Expect = 7e-06
Identities = 73/253 (28%), Positives = 86/253 (33%), Gaps = 33/253 (13%)
Query: 379 GGPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGES 438
G P P P G P PPGP + + +A D+ + P G RG
Sbjct: 87 GTPGNPGPPGPP--GPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPG 144
Query: 439 -AGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPP--PPFDHYLGHKGAAEGKT 495
AG G + +G G EPG E GP G PP PP P D G G A +
Sbjct: 145 PAGAPGPQGFQGNPG-EPG-EPGVSGPMGPRG----PPGPPGKPGDDGEAGKPGKAGERG 198
Query: 496 PDFLLSQSVDQLARPPSL----------------GQAGQLIFCGSIDHLKDNVYRNVMPT 539
P Q P L G+AG G +N M
Sbjct: 199 PPG--PQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP 256
Query: 540 LVIPAHYVRLGGEAGAAGV-GDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGG 598
+P R G AGAAG G++ P PGP P P P PG G G G
Sbjct: 257 RGLPGERGRT-GPAGAAGARGNDGQPGPAGPPGPVG--PAGGPGFPGAPGAKGEAGPTGA 313
Query: 599 GGGEGWGAGRAAP 611
G EG R P
Sbjct: 314 RGPEGAQGPRGEP 326
Score = 47.4 bits (111), Expect = 6e-05
Identities = 72/248 (29%), Positives = 86/248 (34%), Gaps = 40/248 (16%)
Query: 385 APSGDPEAPPPGPLHSAFSSSRD--LASSRDDFFRTKPRSASRPAAE-PSGARGGES--- 438
AP E PPGP A D + + + A P + PSGA G +
Sbjct: 751 APGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTG 810
Query: 439 -AGLKGARSAEGPGGLE--PGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKT 495
G KGAR A+GP G PG R GP G+ PP PP P G KGA
Sbjct: 811 VTGPKGARGAQGPPGATGFPGAAG-RVGPPGSNGN-PGPPGPPGPSGKD-GPKGARGDSG 867
Query: 496 PDFLLSQ-SVDQLARPPS-------------------LGQAGQLIFCGSIDHLKDNVYRN 535
P + + A PP G AGQ G L
Sbjct: 868 PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVG----LPGQRGER 923
Query: 536 VMPTLVIPAHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGE 595
P L P+ G+ GA G + PP P P P +P R PG GP G
Sbjct: 924 GFPGLPGPSGEP---GKQGAPGASGDRGPPGPVGP-PGLTGPAGEPGREGSPGADGPPGR 979
Query: 596 GGGGGGEG 603
G G +G
Sbjct: 980 DGAAGVKG 987
Score = 40.4 bits (93), Expect = 0.007
Identities = 65/239 (27%), Positives = 80/239 (33%), Gaps = 57/239 (23%)
Query: 380 GPL-EPAPSG----DPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRP--AAEPSG 432
GP+ P P+G E PPGP SA +R R + P + P A G
Sbjct: 720 GPIGPPGPAGANGEKGEVGPPGPAGSA--GARGAPGERGETGPPGPAGFAGPPGADGQPG 777
Query: 433 ARGGES-AGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGA- 490
A+G + AG KG A GP +GPSGA P P P G KGA
Sbjct: 778 AKGEQGEAGQKGDAGAPGP-----------QGPSGA-------PGPQGPTG-VTGPKGAR 818
Query: 491 -AEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRL 549
A+G + ++ P S G G P
Sbjct: 819 GAQGPPGATGFPGAAGRVGPPGSNGNPG-------------------------PPGPPGP 853
Query: 550 GGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAGR 608
G+ G G + PP G A P P P PG GP G G G +G R
Sbjct: 854 SGKDGPKGARGDSGPP-GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQR 911
Score = 37.4 bits (85), Expect = 0.057
Identities = 72/246 (29%), Positives = 80/246 (32%), Gaps = 49/246 (19%)
Query: 379 GGPLEPAPSGDP-EAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASR---------PAA 428
G P SG P E PGP+ R L R RT P A+ PA
Sbjct: 234 GAPGVKGESGSPGENGSPGPM-----GPRGLPGERG---RTGPAGAAGARGNDGQPGPAG 285
Query: 429 EPS--GARGGES-AGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYL 485
P G GG G GA+ GP G RGP GA EP +P P
Sbjct: 286 PPGPVGPAGGPGFPGAPGAKGEAGPTGA--------RGPEGAQGPRGEPGTPGSP----- 332
Query: 486 GHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAH 545
G GA+ D + P + G AG G+ P
Sbjct: 333 GPAGASGNPGTDGI----------PGAKGSAGAPGIAGAPGFPGPRGPPGPQGATG-PLG 381
Query: 546 YVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWG 605
GE G AG E P PGPA PQ P G G GE GG G G
Sbjct: 382 PKGQTGEPGIAGFKGEQGPK--GEPGPAG--PQGAPGPAGEEGKRGARGEPGGVGPIGPP 437
Query: 606 AGRAAP 611
R AP
Sbjct: 438 GERGAP 443
Score = 37.0 bits (84), Expect = 0.075
Identities = 67/233 (28%), Positives = 79/233 (33%), Gaps = 44/233 (18%)
Query: 386 PSGDPEAPPPG----PLHSAFSSSRDLASSRDDFFRTKPRSASRP-AAEPSGARGGESAG 440
P G PPG P + F LA + P + P A R GE G
Sbjct: 428 PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP-G 486
Query: 441 LKGARSAEG-PGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDFL 499
L GAR G PG P + + GPSGA E P PP G +GA
Sbjct: 487 LPGARGLTGRPGDAGP---QGKVGPSGAPG---EDGRPGPP-----GPQGAR-------- 527
Query: 500 LSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVG 559
+P +G G G + +P GE GAAG
Sbjct: 528 --------GQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGK----DGETGAAG-- 573
Query: 560 DEPAPPEGTAPGPARAFPQPDPQRPQ-MPGHSGPGGEGGGGGGEGWGAGRAAP 611
P P G A G P P Q +PG GP GEGG G +G AP
Sbjct: 574 --PPGPAGPA-GERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAP 623
Score = 35.0 bits (79), Expect = 0.28
Identities = 54/186 (29%), Positives = 58/186 (31%), Gaps = 59/186 (31%)
Query: 420 PRSASRPAAEPSGARGGESAGLKGARSAEGPGGL--EPGLEEHRRGPSGAAAFLHEPPSP 477
P PA E G RG G KG + A GP G EPG + GP G PP P
Sbjct: 52 PPGPQGPAGE-QGPRGDR--GDKGEKGAPGPRGRDGEPGTPGNP-GPPG-------PPGP 100
Query: 478 PPPFDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVM 537
P P P LG G D VM
Sbjct: 101 PGP------------------------------PGLGGNFAAQMAGGFDEKAGGAQLGVM 130
Query: 538 PTLVIPAHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGG 597
G G G P P APGP + F Q +P P PG SGP G G
Sbjct: 131 Q------------GPMGPMGPRGPPGP--AGAPGP-QGF-QGNPGEPGEPGVSGPMGPRG 174
Query: 598 GGGGEG 603
G G
Sbjct: 175 PPGPPG 180
Score = 35.0 bits (79), Expect = 0.28
Identities = 58/196 (29%), Positives = 68/196 (34%), Gaps = 49/196 (25%)
Query: 379 GGPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGES 438
G P P P G P P GP R + P S PA GARG +
Sbjct: 996 GAPGAPGPPGSPG--PAGPTGKQ--------GDRGEAGAQGPMGPSGPA----GARGIQ- 1040
Query: 439 AGLKGARSAEGPGGLEPGLEEHRRGPSGAAAF--LHEPPSPPPPFDHYLGHKGAAEGKTP 496
G +G R +G G EPG RG G F L P PP P G +GA+ P
Sbjct: 1041 -GPQGPRGDKGEAG-EPG----ERGLKGHRGFTGLQGLPGPPGPS----GDQGASGPAGP 1090
Query: 497 DFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAA 556
P +G +G KD N +P + P GE G A
Sbjct: 1091 S-------GPRGPPGPVGPSG-----------KDGA--NGIPGPIGPPGPRGRSGETGPA 1130
Query: 557 GVGDEPAPPEGTAPGP 572
G P PP PGP
Sbjct: 1131 GPPGNPGPP--GPPGP 1144
Score = 32.7 bits (73), Expect = 1.4
Identities = 68/231 (29%), Positives = 80/231 (34%), Gaps = 39/231 (16%)
Query: 384 PAPSGDPEAP-PPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGESA--G 440
P +G+P P PPGP S +R D P A P + GE G
Sbjct: 839 PGSNGNPGPPGPPGP-----SGKDGPKGARGD--SGPPGRAGEPGLQGPAGPPGEKGEPG 891
Query: 441 LKGARSAEGPGGLEPGLEEHRR-----GPSGAAAFLHEP-PSPPPPFDHYLGHKGAAEGK 494
G AEGP G + GL R G G F P PS P G GA+ +
Sbjct: 892 DDGPSGAEGPPGPQ-GLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQ---GAPGASGDR 947
Query: 495 TPDFLLSQSVDQLARPPSL-GQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEA 553
P + PP L G AG+ GS + P A GE
Sbjct: 948 GPPGPVG--------PPGLTGPAGEPGREGSPG-------ADGPPGRDGAAGVKGDRGET 992
Query: 554 GAAGVGDEPAPPEGTAPGPA-RAFPQPDPQRPQMPGHSGPGGEGGGGGGEG 603
GA G P PP +PGPA Q D G GP G G G +G
Sbjct: 993 GAVGAPGAPGPP--GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQG 1041
Score = 32.0 bits (71), Expect = 2.4
Identities = 24/65 (36%), Positives = 28/65 (43%), Gaps = 6/65 (9%)
Query: 551 GEAGAAGV-GDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAGRA 609
G AG G GD E APGP +P PG+ GP G G G G G A
Sbjct: 57 GPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT-----PGNPGPPGPPGPPGPPGLGGNFA 111
Query: 610 APVSG 614
A ++G
Sbjct: 112 AQMAG 116
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 49.7 bits (117), Expect = 1e-05
Identities = 67/233 (28%), Positives = 81/233 (34%), Gaps = 40/233 (17%)
Query: 383 EPAPSGDPEAPPP--GPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGESAG 440
EP P+G P P GP F + +A + + P P A AG
Sbjct: 474 EPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAG 533
Query: 441 LKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDFLL 500
L GA+ G G PG + + GP G A P P PP G +G A
Sbjct: 534 LPGAKGLTGSPG-SPG-PDGKTGPPGPAGQDGRPGPPGPP-----GARGQA--------- 577
Query: 501 SQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVM--PTLVIPAHYVRLGGEAGAAGV 558
+ P G AG+ G R V P V PA GEAGA G
Sbjct: 578 ----GVMGFPGPKGAAGEPGKAGE---------RGVPGPPGAVGPAGK---DGEAGAQG- 620
Query: 559 GDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAGRAAP 611
P P G A P P +PG +GP GE G G +G AP
Sbjct: 621 ---PPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAP 670
Score = 47.8 bits (112), Expect = 4e-05
Identities = 73/246 (29%), Positives = 86/246 (34%), Gaps = 44/246 (17%)
Query: 379 GGPLEPAPSGDPEAP--PPGPLHSAFSSSRDLASSRDDFFRTKP-RSASRPAAEPSGARG 435
G P EP SG P P PPGP + DD KP R R P GARG
Sbjct: 206 GEPGEPGASG-PMGPRGPPGPP----------GKNGDDGEAGKPGRPGERGPPGPQGARG 254
Query: 436 -GESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGK 494
+AGL G + G GL+ +G +G A EP SP G GA
Sbjct: 255 LPGTAGLPGMKGHRGFSGLDGA-----KGDAGPAGPKGEPGSP--------GENGAPGQM 301
Query: 495 TPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAG 554
P L + RP + G AG G+ P PA G G
Sbjct: 302 GPRGLPGER----GRPGAPGPAGARGNDGATGAAGP-------PGPTGPAGPPGFPGAVG 350
Query: 555 AAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEG-WGAGRAAPVS 613
A G P P R P P P G +GP G G G G GA A ++
Sbjct: 351 AKGEAGPQGPRGSEGPQGVRGEPGP----PGPAGAAGPAGNPGADGQPGAKGANGAPGIA 406
Query: 614 GSVTIP 619
G+ P
Sbjct: 407 GAPGFP 412
Score = 44.7 bits (104), Expect = 4e-04
Identities = 71/244 (29%), Positives = 83/244 (34%), Gaps = 50/244 (20%)
Query: 377 ICGGPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARG- 435
I G P P P G P PPGP + + L+ D+ T S P PSG RG
Sbjct: 134 IPGQPGLPGPPGPP--GPPGPPGLGGNFAPQLSYGYDE-KSTGGISVPGPMG-PSGPRGL 189
Query: 436 GESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKT 495
G G + +GP G EPG E GP G PP PP GK
Sbjct: 190 PGPPGAPGPQGFQGPPG-EPG-EPGASGPMGPRG----PPGPP--------------GKN 229
Query: 496 PDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLG----- 550
D + RP G G R + T +P G
Sbjct: 230 GD---DGEAGKPGRPGERGPPG------------PQGARGLPGTAGLPGMKGHRGFSGLD 274
Query: 551 ---GEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAG 607
G+AG AG EP P G P + P+ P PG GP G G G G AG
Sbjct: 275 GAKGDAGPAGPKGEPGSP-GENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATG-AAG 332
Query: 608 RAAP 611
P
Sbjct: 333 PPGP 336
Score = 44.7 bits (104), Expect = 4e-04
Identities = 68/251 (27%), Positives = 83/251 (33%), Gaps = 48/251 (19%)
Query: 384 PAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGESA---- 439
P P+G A PPGP+ + + +R +A P GA G A
Sbjct: 841 PGPAGP--AGPPGPIGNVGAPGA---------------KGARGSAGPPGATGFPGAAGRV 883
Query: 440 ------GLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHE--PPSPPPPFDHYLGHKGAA 491
G G GP G E G + RG +G A E PP PP P G KG+
Sbjct: 884 GPPGPSGNAGPPGPPGPAGKEGG--KGPRGETGPAGRPGEVGPPGPPGP----AGEKGSP 937
Query: 492 EGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGG 551
P P G AGQ G L P L P+ G
Sbjct: 938 GADGP-------AGAPGTPGPQGIAGQRGVVG----LPGQRGERGFPGLPGPSGEPGKQG 986
Query: 552 EAGAAGVGDEPAP--PEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAGRA 609
+GA+G P P P G A P + + P PG G G G G G
Sbjct: 987 PSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPG 1046
Query: 610 APVSGSVTIPV 620
AP + PV
Sbjct: 1047 APGAPGAPGPV 1057
Score = 43.5 bits (101), Expect = 8e-04
Identities = 63/231 (27%), Positives = 80/231 (34%), Gaps = 20/231 (8%)
Query: 379 GGPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGES 438
G P P P+G P A D + D P + PA P +
Sbjct: 803 GEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGD----AGPPGPAGPAGPPGPIGNVGA 858
Query: 439 AGLKGARSAEGPGGLE--PGLEEH--RRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGK 494
G KGAR + GP G PG GPSG A PP PP P K +G
Sbjct: 859 PGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAG----PPGPPGP-----AGKEGGKGP 909
Query: 495 TPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAG 554
+ + ++ P G AG+ G+ D + V L G+ G
Sbjct: 910 RGETGPAGRPGEVGPPGPPGPAGEKGSPGA-DGPAGAPGTPGPQGIAGQRGVVGLPGQRG 968
Query: 555 AAGVGDEPAPP-EGTAPGPARAFPQPDPQRPQ-MPGHSGPGGEGGGGGGEG 603
G P P E GP+ A + P P PG +GP GE G G G
Sbjct: 969 ERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPG 1019
Score = 42.4 bits (98), Expect = 0.002
Identities = 81/280 (28%), Positives = 101/280 (36%), Gaps = 59/280 (21%)
Query: 379 GGPLEPAPSGDP-EAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPS-----G 432
G P + P G P E PG A + D A+ P + PA P G
Sbjct: 296 GAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGA-----AGPPGPTGPAGPPGFPGAVG 350
Query: 433 ARGGESAGLKGARSAEGPGGL--EPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGA 490
A+G AG +G R +EGP G+ EPG GP+GAA P+ P D G KGA
Sbjct: 351 AKG--EAGPQGPRGSEGPQGVRGEPGPP----GPAGAAG-----PAGNPGADGQPGAKGA 399
Query: 491 --AEG--KTPDFLLSQSVDQLARPPS----LGQAGQLIFCGSIDHLKDNVYRNVMPTLVI 542
A G P F ++ P G +G+ GS K + P V
Sbjct: 400 NGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGS----KGDTGAKGEPGPVG 455
Query: 543 PAHYVRLGGEAGAAGVGDEPAP-----PEGTAPGP-ARAFP----------------QPD 580
GE G G EP P P G GP +R FP P
Sbjct: 456 VQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPG 515
Query: 581 PQRPQ-MPGHSGPGGEGGGGGGEGWGAGRAAPVSGSVTIP 619
P P+ PG +G GE G G +G +P T P
Sbjct: 516 PAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGP 555
Score = 36.6 bits (83), Expect = 0.098
Identities = 55/184 (29%), Positives = 64/184 (34%), Gaps = 32/184 (17%)
Query: 427 AAEPSGARGGESAGLKGARSAEGPGG-LEPGLEEHRRGPSGAAAFLHEPPSP----PPPF 481
A PSGARG G G R +GP G P G GA P +P P
Sbjct: 669 APGPSGARG--ERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGL 726
Query: 482 DHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLV 541
G +GAA P G AG GS KD V R + +
Sbjct: 727 QGMPGERGAAGLPGPK-------------GDRGDAGPKGADGSPG--KDGV-RGLTGPIG 770
Query: 542 IPAHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFP--QPDPQRPQMPGHSGPGGEGGGG 599
P G AGA G E P P AR P + +P P G +GP G G
Sbjct: 771 PP-------GPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQP 823
Query: 600 GGEG 603
G +G
Sbjct: 824 GAKG 827
>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
Length = 703
Score = 49.7 bits (117), Expect = 1e-05
Identities = 61/192 (31%), Positives = 70/192 (36%), Gaps = 31/192 (16%)
Query: 420 PRSASRPAAE-PSGARG----GESAGLKGARSAEGPGGL--EPGLEEHRRGPSGAAAFLH 472
P SA P P G +G G G+ G R +GP GL +PG+ R P H
Sbjct: 363 PGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGA-----H 417
Query: 473 EPPSPPPPFDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNV 532
PP P P G G G L Q D LG GQ G
Sbjct: 418 GPPGPTGPKGEP-GFTGRPGGPGVAGALGQKGD-------LGLPGQPGLRGP-------- 461
Query: 533 YRNVMPTLVIPAHYVRLGGEAGAAGVGDEPAPP-EGTAPGPARAFPQPDPQRPQMPGHSG 591
+ +P L PA + G G G P PP EG A P A P P P PG +G
Sbjct: 462 --SGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITG 519
Query: 592 PGGEGGGGGGEG 603
P G G G G
Sbjct: 520 PPGPPGPPGPPG 531
Score = 37.0 bits (84), Expect = 0.075
Identities = 72/258 (27%), Positives = 87/258 (33%), Gaps = 67/258 (25%)
Query: 383 EPAPSGDP-EAPPPGPLHSAFSSSRDLASSRDDFFRTKP--RSASRPAAEPSGARGGESA 439
EP P G P PPGP F + KP PA P +R G++
Sbjct: 78 EPGPPGKPGPRGPPGP--PGFPGKPGMG---------KPGLHGQPGPAGPPGFSRMGKAG 126
Query: 440 --GLKGARSAEGPGGL--EPGL--EEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEG 493
GL G G GL EPG+ ++ RGP G PP P P + K A+G
Sbjct: 127 PPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPG-------PPGLPGPSGITIPGKPGAQG 179
Query: 494 KT--PDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGG 551
P F PP G G LK + + V G
Sbjct: 180 VPGPPGFQGEPGPQGEPGPP--GDRG----------LKGD-------------NGVGQPG 214
Query: 552 EAGAAGVGDEPAPPEGTAPGPARAFPQP----------DPQRPQMPGHSGPGGEGGGGGG 601
GA G G P PP PGPA +P D PG GP GE G G
Sbjct: 215 LPGAPGQGGAPGPPG--LPGPA-GLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGP 271
Query: 602 EGWGAGRAAPVSGSVTIP 619
+G V G+ +P
Sbjct: 272 KGPPGVDGVGVPGAAGLP 289
Score = 34.7 bits (78), Expect = 0.37
Identities = 65/234 (27%), Positives = 78/234 (33%), Gaps = 53/234 (22%)
Query: 383 EPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGESAGLK 442
EP P G+P PPG D D+ +P + +GG
Sbjct: 189 EPGPQGEPG--PPG----------DRGLKGDN-------GVGQPGLPGAPGQGGAP---- 225
Query: 443 GARSAEGPGGL-EPGLEEHRRGPSGAAAFLHE--PPSPPPPFDHYLGHKGAAEGKTPDFL 499
G GP GL +PGL+ G GA E PP P P G GA K P
Sbjct: 226 GPPGLPGPAGLGKPGLD----GLPGAPGDKGESGPPGVPGP----RGEPGAVGPKGPP-- 275
Query: 500 LSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVG 559
VD + P + G G G+ K P L+ P Y G G G
Sbjct: 276 ---GVDGVGVPGAAGLPGPQGPSGA----KGEPGTRGPPGLIGPTGY----GMPGLPG-- 322
Query: 560 DEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGG--GEGWGAGRAAP 611
P G A P + +P PG GP G GG G G GR P
Sbjct: 323 --PKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGP 374
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 48.5 bits (114), Expect = 2e-05
Identities = 72/275 (26%), Positives = 95/275 (34%), Gaps = 54/275 (19%)
Query: 379 GGPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGES 438
G P P PSG EA PPGP P P A + R GE
Sbjct: 1354 GQPGPPGPSG--EAGPPGP----------------------PGKRGPPGAAGAEGRQGEK 1389
Query: 439 AGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDF 498
G KG AEGP G + GP G P P P G +G G +
Sbjct: 1390 -GAKGEAGAEGPPG--------KTGPVGPQG----PAGKPGPE----GLRGIP-GPVGEQ 1431
Query: 499 LLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGV 558
L + Q P +G G G + + ++ + P G
Sbjct: 1432 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1491
Query: 559 GDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGG--GGGGEGWGAGRAAPVS--- 613
G A +G PGPA P P P +PG GP G G G G+ +G P
Sbjct: 1492 GSPGAKGDGGIPGPAGPLGPPGP--PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1549
Query: 614 --GSV--TIPVLFNESTMAQLNGELQALTEKKLLE 644
G V +P+L ++ T G +QA + +L+
Sbjct: 1550 PPGEVIQPLPILSSKKTRRHTEG-MQADADDNILD 1583
Score = 47.4 bits (111), Expect = 6e-05
Identities = 62/209 (29%), Positives = 71/209 (33%), Gaps = 47/209 (22%)
Query: 419 KPRSASRPAAEPSGARGGESAGLKGARSAEGPGGLEPGLEEHR--RGPSGAAAFLHEPPS 476
KP RP A+ GE G KG R +G GL PG + HR RGP G PP
Sbjct: 587 KPGKRGRPGADGGRGMPGEP-GAKGDRGFDGLPGL-PGDKGHRGERGPQG-------PPG 637
Query: 477 PPPPF-----DHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDN 531
PP D +G +G P LL P + GQ G G
Sbjct: 638 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPR----GTPGAPGQPGMAGVDGP------- 686
Query: 532 VYRNVMPTLVIPAHYVRLG--GEAGAAGVGDEPAP-----PEGTAPGPARAFPQPDPQRP 584
P +G GE G G P P P+G P PQ P
Sbjct: 687 -----------PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLA 735
Query: 585 QMPGHSGPGGEGG--GGGGEGWGAGRAAP 611
+PG GP G G G GE G P
Sbjct: 736 GLPGADGPPGHPGKEGQSGEKGALGPPGP 764
Score = 40.0 bits (92), Expect = 0.009
Identities = 65/241 (26%), Positives = 82/241 (34%), Gaps = 46/241 (19%)
Query: 420 PRSASRPAAEPSGARGGESA----GLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLH-EP 474
PR P P G+RG G KG +GP G P E +GP G F +
Sbjct: 890 PRGQRGPTG-PRGSRGARGPTGKPGPKGTSGGDGPPG--PPGERGPQGPQGPVGFPGPKG 946
Query: 475 PSPPPPFDHYLGHKGAA-----EGKT----PDFLLSQS--------VDQLARPPSLGQAG 517
P PP D GH G +GKT P ++ + + P G G
Sbjct: 947 PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPG 1006
Query: 518 QLIFCGSIDHLKDNVYRNVMPTLVI----PAHYVRLGGEAGAAGV--------GDEPAPP 565
+ G+ K+ + P + PA GE G G G+ P P
Sbjct: 1007 EQGLPGAAG--KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGP 1064
Query: 566 EGTAPGPAR------AFPQPDPQRPQMPGHSGPGGEGGGGGGEG-WGAGRAAPVSGSVTI 618
G P A P P RP G GP GE G G +G G V G V +
Sbjct: 1065 PGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL 1124
Query: 619 P 619
P
Sbjct: 1125 P 1125
Score = 39.3 bits (90), Expect = 0.015
Identities = 49/189 (25%), Positives = 60/189 (31%), Gaps = 49/189 (25%)
Query: 432 GARGGESAGLKGARSAEGPGGLE----PGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGH 487
G +G E G +G GP GL+ P E+ G G PP PP P G
Sbjct: 1192 GQKGDE--GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMG----PPGPPGPRGPQ-GP 1244
Query: 488 KGAAEGKTPDFLLSQ--SVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAH 545
GA + P + V + P G G P
Sbjct: 1245 NGADGPQGPPGSVGSVGGVGEKGEPGEAGNPG-------------------------PPG 1279
Query: 546 YVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPD-----------PQRPQMPGHSGPGG 594
+GG G G E PP P A+ P D P P PG GP G
Sbjct: 1280 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1339
Query: 595 EGGGGGGEG 603
+ G GG +G
Sbjct: 1340 QDGVGGDKG 1348
Score = 36.6 bits (83), Expect = 0.098
Identities = 50/182 (27%), Positives = 65/182 (35%), Gaps = 20/182 (10%)
Query: 440 GLKGARSAEG-PGGLEPG-LEEHRRGPSGAAAFLHEP----PSPPPPFDHYLGHKGAAEG 493
G G + +G P +EPG L E GP+G A + P P+ PP G G
Sbjct: 432 GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPG- 490
Query: 494 KTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVY--RNVMPTLVIPAHYVRLGG 551
D L PP G L F D K + ++ + L G
Sbjct: 491 -------LPGADGLPGPP--GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRG 541
Query: 552 EAGAAGVGDEPAPPEGTAPGPARAFP-QPDPQRPQ-MPGHSGPGGEGGGGGGEGWGAGRA 609
G G+ P P G A+ P PQ P+ + G GP G+ G G G GR
Sbjct: 542 PPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRG 601
Query: 610 AP 611
P
Sbjct: 602 MP 603
Score = 33.1 bits (74), Expect = 1.1
Identities = 52/191 (27%), Positives = 66/191 (34%), Gaps = 29/191 (15%)
Query: 432 GARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHE---PPSPPPPFDHYLGHK 488
G RG G +G GPGG+ +GP+G + E P P PP + L
Sbjct: 961 GQRG--ETGFQGKTGPPGPGGVVGP-----QGPTGETGPIGERGHPGPPGPPGEQGLPGA 1013
Query: 489 GAAEGKTPDFLLSQSVDQLARPPSL-GQAGQLIFCGS--IDHLKDNVYRNVMPTLVIPAH 545
EG D Q + P L G G+ G+ LK P V
Sbjct: 1014 AGKEGAKGD-PGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1072
Query: 546 YVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQ-------------MPGHSGP 592
G AG G+ P P PGPA P + PQ +PG +GP
Sbjct: 1073 ERGSAGTAGPIGLPGRPGPQG--PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGP 1130
Query: 593 GGEGGGGGGEG 603
G G G +G
Sbjct: 1131 AGSPGEDGDKG 1141
Score = 32.7 bits (73), Expect = 1.4
Identities = 21/61 (34%), Positives = 26/61 (42%), Gaps = 10/61 (16%)
Query: 543 PAHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGE 602
PA +GG+ G G +P PP GP+ P P PG GP G G G +
Sbjct: 1337 PAGQDGVGGDKGEDGDPGQPGPP-----GPSGEAGPPGP-----PGKRGPPGAAGAEGRQ 1386
Query: 603 G 603
G
Sbjct: 1387 G 1387
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 48.5 bits (114), Expect = 2e-05
Identities = 72/275 (26%), Positives = 95/275 (34%), Gaps = 54/275 (19%)
Query: 379 GGPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGES 438
G P P PSG EA PPGP P P A + R GE
Sbjct: 1303 GQPGPPGPSG--EAGPPGP----------------------PGKRGPPGAAGAEGRQGEK 1338
Query: 439 AGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDF 498
G KG AEGP G + GP G P P P G +G G +
Sbjct: 1339 -GAKGEAGAEGPPG--------KTGPVGPQG----PAGKPGPE----GLRGIP-GPVGEQ 1380
Query: 499 LLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGV 558
L + Q P +G G G + + ++ + P G
Sbjct: 1381 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1440
Query: 559 GDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGG--GGGGEGWGAGRAAPVS--- 613
G A +G PGPA P P P +PG GP G G G G+ +G P
Sbjct: 1441 GSPGAKGDGGIPGPAGPLGPPGP--PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1498
Query: 614 --GSV--TIPVLFNESTMAQLNGELQALTEKKLLE 644
G V +P+L ++ T G +QA + +L+
Sbjct: 1499 PPGEVIQPLPILSSKKTRRHTEG-MQADADDNILD 1532
Score = 47.4 bits (111), Expect = 6e-05
Identities = 62/209 (29%), Positives = 71/209 (33%), Gaps = 47/209 (22%)
Query: 419 KPRSASRPAAEPSGARGGESAGLKGARSAEGPGGLEPGLEEHR--RGPSGAAAFLHEPPS 476
KP RP A+ GE G KG R +G GL PG + HR RGP G PP
Sbjct: 536 KPGKRGRPGADGGRGMPGEP-GAKGDRGFDGLPGL-PGDKGHRGERGPQG-------PPG 586
Query: 477 PPPPF-----DHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDN 531
PP D +G +G P LL P + GQ G G
Sbjct: 587 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPR----GTPGAPGQPGMAGVDGP------- 635
Query: 532 VYRNVMPTLVIPAHYVRLG--GEAGAAGVGDEPAP-----PEGTAPGPARAFPQPDPQRP 584
P +G GE G G P P P+G P PQ P
Sbjct: 636 -----------PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLA 684
Query: 585 QMPGHSGPGGEGG--GGGGEGWGAGRAAP 611
+PG GP G G G GE G P
Sbjct: 685 GLPGADGPPGHPGKEGQSGEKGALGPPGP 713
Score = 40.0 bits (92), Expect = 0.009
Identities = 65/241 (26%), Positives = 82/241 (34%), Gaps = 46/241 (19%)
Query: 420 PRSASRPAAEPSGARGGESA----GLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLH-EP 474
PR P P G+RG G KG +GP G P E +GP G F +
Sbjct: 839 PRGQRGPTG-PRGSRGARGPTGKPGPKGTSGGDGPPG--PPGERGPQGPQGPVGFPGPKG 895
Query: 475 PSPPPPFDHYLGHKGAA-----EGKT----PDFLLSQS--------VDQLARPPSLGQAG 517
P PP D GH G +GKT P ++ + + P G G
Sbjct: 896 PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPG 955
Query: 518 QLIFCGSIDHLKDNVYRNVMPTLVI----PAHYVRLGGEAGAAGV--------GDEPAPP 565
+ G+ K+ + P + PA GE G G G+ P P
Sbjct: 956 EQGLPGAAG--KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGP 1013
Query: 566 EGTAPGPAR------AFPQPDPQRPQMPGHSGPGGEGGGGGGEG-WGAGRAAPVSGSVTI 618
G P A P P RP G GP GE G G +G G V G V +
Sbjct: 1014 PGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL 1073
Query: 619 P 619
P
Sbjct: 1074 P 1074
Score = 39.3 bits (90), Expect = 0.015
Identities = 49/189 (25%), Positives = 60/189 (31%), Gaps = 49/189 (25%)
Query: 432 GARGGESAGLKGARSAEGPGGLE----PGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGH 487
G +G E G +G GP GL+ P E+ G G PP PP P G
Sbjct: 1141 GQKGDE--GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMG----PPGPPGPRGPQ-GP 1193
Query: 488 KGAAEGKTPDFLLSQ--SVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAH 545
GA + P + V + P G G P
Sbjct: 1194 NGADGPQGPPGSVGSVGGVGEKGEPGEAGNPG-------------------------PPG 1228
Query: 546 YVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPD-----------PQRPQMPGHSGPGG 594
+GG G G E PP P A+ P D P P PG GP G
Sbjct: 1229 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1288
Query: 595 EGGGGGGEG 603
+ G GG +G
Sbjct: 1289 QDGVGGDKG 1297
Score = 36.6 bits (83), Expect = 0.098
Identities = 50/182 (27%), Positives = 65/182 (35%), Gaps = 20/182 (10%)
Query: 440 GLKGARSAEG-PGGLEPG-LEEHRRGPSGAAAFLHEP----PSPPPPFDHYLGHKGAAEG 493
G G + +G P +EPG L E GP+G A + P P+ PP G G
Sbjct: 381 GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPG- 439
Query: 494 KTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVY--RNVMPTLVIPAHYVRLGG 551
D L PP G L F D K + ++ + L G
Sbjct: 440 -------LPGADGLPGPP--GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRG 490
Query: 552 EAGAAGVGDEPAPPEGTAPGPARAFP-QPDPQRPQ-MPGHSGPGGEGGGGGGEGWGAGRA 609
G G+ P P G A+ P PQ P+ + G GP G+ G G G GR
Sbjct: 491 PPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRG 550
Query: 610 AP 611
P
Sbjct: 551 MP 552
Score = 33.1 bits (74), Expect = 1.1
Identities = 52/191 (27%), Positives = 66/191 (34%), Gaps = 29/191 (15%)
Query: 432 GARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHE---PPSPPPPFDHYLGHK 488
G RG G +G GPGG+ +GP+G + E P P PP + L
Sbjct: 910 GQRG--ETGFQGKTGPPGPGGVVGP-----QGPTGETGPIGERGHPGPPGPPGEQGLPGA 962
Query: 489 GAAEGKTPDFLLSQSVDQLARPPSL-GQAGQLIFCGS--IDHLKDNVYRNVMPTLVIPAH 545
EG D Q + P L G G+ G+ LK P V
Sbjct: 963 AGKEGAKGD-PGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1021
Query: 546 YVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQ-------------MPGHSGP 592
G AG G+ P P PGPA P + PQ +PG +GP
Sbjct: 1022 ERGSAGTAGPIGLPGRPGPQG--PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGP 1079
Query: 593 GGEGGGGGGEG 603
G G G +G
Sbjct: 1080 AGSPGEDGDKG 1090
Score = 32.7 bits (73), Expect = 1.4
Identities = 21/61 (34%), Positives = 26/61 (42%), Gaps = 10/61 (16%)
Query: 543 PAHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGE 602
PA +GG+ G G +P PP GP+ P P PG GP G G G +
Sbjct: 1286 PAGQDGVGGDKGEDGDPGQPGPP-----GPSGEAGPPGP-----PGKRGPPGAAGAEGRQ 1335
Query: 603 G 603
G
Sbjct: 1336 G 1336
>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
sapiens]
Length = 1806
Score = 48.5 bits (114), Expect = 2e-05
Identities = 72/275 (26%), Positives = 95/275 (34%), Gaps = 54/275 (19%)
Query: 379 GGPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGES 438
G P P PSG EA PPGP P P A + R GE
Sbjct: 1342 GQPGPPGPSG--EAGPPGP----------------------PGKRGPPGAAGAEGRQGEK 1377
Query: 439 AGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDF 498
G KG AEGP G + GP G P P P G +G G +
Sbjct: 1378 -GAKGEAGAEGPPG--------KTGPVGPQG----PAGKPGPE----GLRGIP-GPVGEQ 1419
Query: 499 LLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGV 558
L + Q P +G G G + + ++ + P G
Sbjct: 1420 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1479
Query: 559 GDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGG--GGGGEGWGAGRAAPVS--- 613
G A +G PGPA P P P +PG GP G G G G+ +G P
Sbjct: 1480 GSPGAKGDGGIPGPAGPLGPPGP--PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1537
Query: 614 --GSV--TIPVLFNESTMAQLNGELQALTEKKLLE 644
G V +P+L ++ T G +QA + +L+
Sbjct: 1538 PPGEVIQPLPILSSKKTRRHTEG-MQADADDNILD 1571
Score = 47.4 bits (111), Expect = 6e-05
Identities = 62/209 (29%), Positives = 71/209 (33%), Gaps = 47/209 (22%)
Query: 419 KPRSASRPAAEPSGARGGESAGLKGARSAEGPGGLEPGLEEHR--RGPSGAAAFLHEPPS 476
KP RP A+ GE G KG R +G GL PG + HR RGP G PP
Sbjct: 575 KPGKRGRPGADGGRGMPGEP-GAKGDRGFDGLPGL-PGDKGHRGERGPQG-------PPG 625
Query: 477 PPPPF-----DHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDN 531
PP D +G +G P LL P + GQ G G
Sbjct: 626 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPR----GTPGAPGQPGMAGVDGP------- 674
Query: 532 VYRNVMPTLVIPAHYVRLG--GEAGAAGVGDEPAP-----PEGTAPGPARAFPQPDPQRP 584
P +G GE G G P P P+G P PQ P
Sbjct: 675 -----------PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLA 723
Query: 585 QMPGHSGPGGEGG--GGGGEGWGAGRAAP 611
+PG GP G G G GE G P
Sbjct: 724 GLPGADGPPGHPGKEGQSGEKGALGPPGP 752
Score = 40.0 bits (92), Expect = 0.009
Identities = 65/241 (26%), Positives = 82/241 (34%), Gaps = 46/241 (19%)
Query: 420 PRSASRPAAEPSGARGGESA----GLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLH-EP 474
PR P P G+RG G KG +GP G P E +GP G F +
Sbjct: 878 PRGQRGPTG-PRGSRGARGPTGKPGPKGTSGGDGPPG--PPGERGPQGPQGPVGFPGPKG 934
Query: 475 PSPPPPFDHYLGHKGAA-----EGKT----PDFLLSQS--------VDQLARPPSLGQAG 517
P PP D GH G +GKT P ++ + + P G G
Sbjct: 935 PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPG 994
Query: 518 QLIFCGSIDHLKDNVYRNVMPTLVI----PAHYVRLGGEAGAAGV--------GDEPAPP 565
+ G+ K+ + P + PA GE G G G+ P P
Sbjct: 995 EQGLPGAAG--KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGP 1052
Query: 566 EGTAPGPAR------AFPQPDPQRPQMPGHSGPGGEGGGGGGEG-WGAGRAAPVSGSVTI 618
G P A P P RP G GP GE G G +G G V G V +
Sbjct: 1053 PGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL 1112
Query: 619 P 619
P
Sbjct: 1113 P 1113
Score = 39.3 bits (90), Expect = 0.015
Identities = 49/189 (25%), Positives = 60/189 (31%), Gaps = 49/189 (25%)
Query: 432 GARGGESAGLKGARSAEGPGGLE----PGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGH 487
G +G E G +G GP GL+ P E+ G G PP PP P G
Sbjct: 1180 GQKGDE--GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMG----PPGPPGPRGPQ-GP 1232
Query: 488 KGAAEGKTPDFLLSQ--SVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAH 545
GA + P + V + P G G P
Sbjct: 1233 NGADGPQGPPGSVGSVGGVGEKGEPGEAGNPG-------------------------PPG 1267
Query: 546 YVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPD-----------PQRPQMPGHSGPGG 594
+GG G G E PP P A+ P D P P PG GP G
Sbjct: 1268 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1327
Query: 595 EGGGGGGEG 603
+ G GG +G
Sbjct: 1328 QDGVGGDKG 1336
Score = 36.6 bits (83), Expect = 0.098
Identities = 50/182 (27%), Positives = 65/182 (35%), Gaps = 20/182 (10%)
Query: 440 GLKGARSAEG-PGGLEPG-LEEHRRGPSGAAAFLHEP----PSPPPPFDHYLGHKGAAEG 493
G G + +G P +EPG L E GP+G A + P P+ PP G G
Sbjct: 420 GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPG- 478
Query: 494 KTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVY--RNVMPTLVIPAHYVRLGG 551
D L PP G L F D K + ++ + L G
Sbjct: 479 -------LPGADGLPGPP--GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRG 529
Query: 552 EAGAAGVGDEPAPPEGTAPGPARAFP-QPDPQRPQ-MPGHSGPGGEGGGGGGEGWGAGRA 609
G G+ P P G A+ P PQ P+ + G GP G+ G G G GR
Sbjct: 530 PPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRG 589
Query: 610 AP 611
P
Sbjct: 590 MP 591
Score = 33.1 bits (74), Expect = 1.1
Identities = 52/191 (27%), Positives = 66/191 (34%), Gaps = 29/191 (15%)
Query: 432 GARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHE---PPSPPPPFDHYLGHK 488
G RG G +G GPGG+ +GP+G + E P P PP + L
Sbjct: 949 GQRG--ETGFQGKTGPPGPGGVVGP-----QGPTGETGPIGERGHPGPPGPPGEQGLPGA 1001
Query: 489 GAAEGKTPDFLLSQSVDQLARPPSL-GQAGQLIFCGS--IDHLKDNVYRNVMPTLVIPAH 545
EG D Q + P L G G+ G+ LK P V
Sbjct: 1002 AGKEGAKGD-PGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1060
Query: 546 YVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQ-------------MPGHSGP 592
G AG G+ P P PGPA P + PQ +PG +GP
Sbjct: 1061 ERGSAGTAGPIGLPGRPGPQG--PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGP 1118
Query: 593 GGEGGGGGGEG 603
G G G +G
Sbjct: 1119 AGSPGEDGDKG 1129
Score = 32.7 bits (73), Expect = 1.4
Identities = 21/61 (34%), Positives = 26/61 (42%), Gaps = 10/61 (16%)
Query: 543 PAHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGE 602
PA +GG+ G G +P PP GP+ P P PG GP G G G +
Sbjct: 1325 PAGQDGVGGDKGEDGDPGQPGPP-----GPSGEAGPPGP-----PGKRGPPGAAGAEGRQ 1374
Query: 603 G 603
G
Sbjct: 1375 G 1375
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 48.5 bits (114), Expect = 2e-05
Identities = 93/370 (25%), Positives = 123/370 (33%), Gaps = 63/370 (17%)
Query: 433 ARGGESAGLKGARSAEGPGGLEPGL---EEHRRGPSGAAAFLHEPPSPPP------PFDH 483
A+G E ++G + EGP P L + P AA P P P P
Sbjct: 558 AKGPELMAIEGLENGEGPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQE 617
Query: 484 YLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIP 543
+G + G S +Q A PS G +L + R +P
Sbjct: 618 SIGARSRGSG--------HSQEQPAPQPSGGDPSP----PQERNLPEGTERPPKLCSSLP 665
Query: 544 AH----YVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQ--------PDPQRPQMPGHS- 590
YV + + G +P G PG AF PDP RP+ HS
Sbjct: 666 GQGPPPYVFMYPQ------GSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSL 719
Query: 591 -GPGGEGGGGGGEGWGAGRAAPVSGSVTIPVLFNESTMAQLNGELQAL-TEKKLLELGVK 648
PG G GE G PV + L + +T+ + G + T + +
Sbjct: 720 SRPGPTEGDAEGEAEG-----PVGST-----LGSYATLTRRPGRSALVRTSPSVTPTPAR 769
Query: 649 PHPRAWFVSLDGRSNSQVRHSYIDLQAGGGARSTDASLDSGVDVHEARPARRRPAREERE 708
PR+ +L R L + G LD E RR R E
Sbjct: 770 GTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRR--RTLSE 827
Query: 709 RAPPAAPPPPPAPPRLALS--------EDTEPSSSESRTGLCSPEDNSLT-PLLDEVAAP 759
A P+ PP PPAP A E T PS S GL E+ +LT + A P
Sbjct: 828 PAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGP 887
Query: 760 EGRAATVPRG 769
R VP G
Sbjct: 888 PPRETPVPPG 897
Score = 32.0 bits (71), Expect = 2.4
Identities = 94/384 (24%), Positives = 116/384 (30%), Gaps = 118/384 (30%)
Query: 386 PSGDPEAPPPGPLHS---AFSSSRDLASSRDDFFRTKPR--SASRPAAEPSGARGGESAG 440
P G P +P PGP AFS ++ D R K R S SRP A G
Sbjct: 677 PQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEG----- 731
Query: 441 LKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDFLL 500
AEGP G G G +A + PS P A G TP
Sbjct: 732 -----EAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPT---------PARG-TP---R 773
Query: 501 SQSVDQLAR---PPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAA- 556
SQS AR PP P RL +G +
Sbjct: 774 SQSFALRARRKGPP-------------------------------PPPPKRLSSVSGPSP 802
Query: 557 ---GVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAGRAAPVS 613
+ + P P EG A GP R + PG P G E G P
Sbjct: 803 EPPPLDESPGPKEG-ATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSR 861
Query: 614 GSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPHPRAWFVSLDGRSNSQVRHSYIDL 673
GS +GE E+ L + +P P
Sbjct: 862 GS---------------SGEGLPFAEEGNLTIKQRPKP---------------------- 884
Query: 674 QAGGGARSTDASLDSGVDVHEARPARRRPAREERERAPPA--------APPPPPAPPRLA 725
AG R T ++ E+ +RRP ERE A A P P AP
Sbjct: 885 -AGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSP 943
Query: 726 LSEDTEPSSSESRTGLCSPEDNSL 749
++ P+SS L PE +SL
Sbjct: 944 TPGESPPASS-----LPQPEPSSL 962
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 48.5 bits (114), Expect = 2e-05
Identities = 93/370 (25%), Positives = 123/370 (33%), Gaps = 63/370 (17%)
Query: 433 ARGGESAGLKGARSAEGPGGLEPGL---EEHRRGPSGAAAFLHEPPSPPP------PFDH 483
A+G E ++G + EGP P L + P AA P P P P
Sbjct: 640 AKGPELMAIEGLENGEGPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQE 699
Query: 484 YLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIP 543
+G + G S +Q A PS G +L + R +P
Sbjct: 700 SIGARSRGSG--------HSQEQPAPQPSGGDPSP----PQERNLPEGTERPPKLCSSLP 747
Query: 544 AH----YVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQ--------PDPQRPQMPGHS- 590
YV + + G +P G PG AF PDP RP+ HS
Sbjct: 748 GQGPPPYVFMYPQ------GSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSL 801
Query: 591 -GPGGEGGGGGGEGWGAGRAAPVSGSVTIPVLFNESTMAQLNGELQAL-TEKKLLELGVK 648
PG G GE G PV + L + +T+ + G + T + +
Sbjct: 802 SRPGPTEGDAEGEAEG-----PVGST-----LGSYATLTRRPGRSALVRTSPSVTPTPAR 851
Query: 649 PHPRAWFVSLDGRSNSQVRHSYIDLQAGGGARSTDASLDSGVDVHEARPARRRPAREERE 708
PR+ +L R L + G LD E RR R E
Sbjct: 852 GTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRR--RTLSE 909
Query: 709 RAPPAAPPPPPAPPRLALS--------EDTEPSSSESRTGLCSPEDNSLT-PLLDEVAAP 759
A P+ PP PPAP A E T PS S GL E+ +LT + A P
Sbjct: 910 PAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGP 969
Query: 760 EGRAATVPRG 769
R VP G
Sbjct: 970 PPRETPVPPG 979
Score = 32.0 bits (71), Expect = 2.4
Identities = 94/384 (24%), Positives = 116/384 (30%), Gaps = 118/384 (30%)
Query: 386 PSGDPEAPPPGPLHS---AFSSSRDLASSRDDFFRTKPR--SASRPAAEPSGARGGESAG 440
P G P +P PGP AFS ++ D R K R S SRP A G
Sbjct: 759 PQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEG----- 813
Query: 441 LKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDFLL 500
AEGP G G G +A + PS P A G TP
Sbjct: 814 -----EAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPT---------PARG-TP---R 855
Query: 501 SQSVDQLAR---PPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAA- 556
SQS AR PP P RL +G +
Sbjct: 856 SQSFALRARRKGPP-------------------------------PPPPKRLSSVSGPSP 884
Query: 557 ---GVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAGRAAPVS 613
+ + P P EG A GP R + PG P G E G P
Sbjct: 885 EPPPLDESPGPKEG-ATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSR 943
Query: 614 GSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPHPRAWFVSLDGRSNSQVRHSYIDL 673
GS +GE E+ L + +P P
Sbjct: 944 GS---------------SGEGLPFAEEGNLTIKQRPKP---------------------- 966
Query: 674 QAGGGARSTDASLDSGVDVHEARPARRRPAREERERAPPA--------APPPPPAPPRLA 725
AG R T ++ E+ +RRP ERE A A P P AP
Sbjct: 967 -AGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSP 1025
Query: 726 LSEDTEPSSSESRTGLCSPEDNSL 749
++ P+SS L PE +SL
Sbjct: 1026 TPGESPPASS-----LPQPEPSSL 1044
>gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]
Length = 663
Score = 47.0 bits (110), Expect = 7e-05
Identities = 64/241 (26%), Positives = 79/241 (32%), Gaps = 44/241 (18%)
Query: 381 PLEPAPSGDPEAPPPGP--------LHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSG 432
PL P PS P PPP P +S S SR DF + SA+ PAA G
Sbjct: 156 PLPPTPSPPPPPPPPPPPALSGYTTTNSGGGGSSGKGHSR-DFVLRRDLSATAPAAAMHG 214
Query: 433 A-RGGESAGLKGARSAEGP----GGLEPGLEEHRRGPSGAAA-----FLHEPPSPPPPFD 482
A GGE G+ P G+ GP G+ LH+ P P
Sbjct: 215 APLGGEQRSGTGSPQHPAPPPHSAGMFISASGTYAGPDGSGGPALFPALHDTPGAPGGHP 274
Query: 483 HYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVI 542
H L + + + A PP ++G D Y V
Sbjct: 275 HPLNGQMRLGLAAAAAAAAAELYGRAEPPFAPRSG------------DAHYGAVAAAAAA 322
Query: 543 PAH-------YVRLGGEAGAAGVGDEP-----APPEGTAPGPARAFPQPDPQRPQMPGHS 590
H + L A AA G P APP P PA A P P +PG +
Sbjct: 323 ALHGYGAVNLNLNLAAAAAAAAAGPGPHLQHHAPPPAPPPPPAPA-QHPHQHHPHLPGAA 381
Query: 591 G 591
G
Sbjct: 382 G 382
Score = 43.5 bits (101), Expect = 8e-04
Identities = 84/338 (24%), Positives = 105/338 (31%), Gaps = 71/338 (21%)
Query: 394 PPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGESAGLKGARSAEGPGGL 453
P GP H A +S+ L+ F + P A + AR GA S GG
Sbjct: 90 PLGPEHMAQASTLGLSPPSQAF-------PAHPEAPAAAARAAALVAHPGAGSYPCGGGS 142
Query: 454 EPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSL 513
P+ PP PPPP P L + S
Sbjct: 143 SGAQPSAPPPPAPPLPPTPSPPPPPPP-------------PPPPALSGYTTTNSGGGGSS 189
Query: 514 GQAGQLIFCGSIDHLKDNVYRNVMPTLVIPA--HYVRLGGEA-GAAGVGDEPAPPEGTAP 570
G+ H +D V R + A H LGGE G PAPP P
Sbjct: 190 GKG----------HSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGTGSPQHPAPP----P 235
Query: 571 GPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAGRAAPVSGSVTIPVLFNESTMAQL 630
A F ++GP G GG AP G P L
Sbjct: 236 HSAGMFISASGT------YAGPDGSGGPALFPALHDTPGAP--GGHPHP----------L 277
Query: 631 NGELQALTEKKLLELGVKPHPRAWFVSLDGRSNSQVRHSYIDLQAGGGARSTDASLDSGV 690
NG+++ LG+ A L GR+ D G A + A+L
Sbjct: 278 NGQMR---------LGLAAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYG 328
Query: 691 DVH-------EARPARRRPAREERERAPPAAPPPPPAP 721
V+ A A P + APP APPPPPAP
Sbjct: 329 AVNLNLNLAAAAAAAAAGPGPHLQHHAPPPAPPPPPAP 366
Score = 30.8 bits (68), Expect = 5.4
Identities = 41/142 (28%), Positives = 53/142 (37%), Gaps = 32/142 (22%)
Query: 379 GGP-LEPAPSGDPEAPP--PGPLHSAFS---SSRDLASSRDDFFRTKPRSASRPAAEPSG 432
GGP L PA P AP P PL+ ++ A++ + + R +P A R G
Sbjct: 255 GGPALFPALHDTPGAPGGHPHPLNGQMRLGLAAAAAAAAAELYGRAEPPFAPRSGDAHYG 314
Query: 433 A-RGGESAGLKG--------------ARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSP 477
A +A L G A +A GPG P L+ H P+ PP P
Sbjct: 315 AVAAAAAAALHGYGAVNLNLNLAAAAAAAAAGPG---PHLQHHAPPPA--------PPPP 363
Query: 478 PPPFDHYLGHKGAAEGKTPDFL 499
P P H H G FL
Sbjct: 364 PAPAQHPHQHHPHLPGAAGAFL 385
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
[Homo sapiens]
Length = 1125
Score = 46.6 bits (109), Expect = 9e-05
Identities = 60/230 (26%), Positives = 75/230 (32%), Gaps = 61/230 (26%)
Query: 381 PLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPS--------- 431
P+ P S P PP + + S +R A S D K ++ P A P+
Sbjct: 746 PITPPVSIPPPHTPPISIPNLVSGARGNAESGDS---VKMYGSAVPPAAPTNLPTPPVTQ 802
Query: 432 --------GARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHE-PPSPPPPFD 482
G G GL+ + G G PGL +R P L P PP P
Sbjct: 803 PVSLLGTQGVAPGPVIGLQAPST--GLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMP 860
Query: 483 HYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVI 542
++ H+G G A PP G G
Sbjct: 861 PHMMHRGPPPGP----------GGFAMPPPHGMKGPF----------------------- 887
Query: 543 PAH--YVRLGGEAGAAGVGDEPAPPE---GTAPGPARAFPQPDPQRPQMP 587
P H +VR GG G G G P PE G P + QP PQ PQ P
Sbjct: 888 PPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQP 937
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 45.8 bits (107), Expect = 2e-04
Identities = 73/261 (27%), Positives = 91/261 (34%), Gaps = 62/261 (23%)
Query: 379 GGPLEPAPSGDPEAPPPGPLHSAFSSSR---DLASSRDDFFRTKPRS------------- 422
G P P P G P P P L FS+ D S P S
Sbjct: 168 GQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQ 227
Query: 423 ASRPAAEPSGARGGES----AGLKGARSAEGPGGLEPGL--EEHRRGPSGAAAFLHEP-- 474
+ A P+G G G G+R EGP G +PG E R G G F P
Sbjct: 228 GQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPG-KPGEDGEPGRNGNPGEVGFAGSPGA 286
Query: 475 ---PSPP--PPFDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLK 529
P P P + GHKG L ++ P S G+AG G++ L
Sbjct: 287 RGFPGAPGLPGLKGHRGHKG----------LEGPKGEVGAPGSKGEAGPTGPMGAMGPLG 336
Query: 530 DNVYRNVMPTLVIPAHYVRLG-----GEAGAAGVGDEPAP--PEGTAPGPARAFPQPDPQ 582
+P RLG G+ GA G+ +P P P G PG + P
Sbjct: 337 PR---------GMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLG-IPGSSGF-----PG 381
Query: 583 RPQMPGHSGPGGEGGGGGGEG 603
P M G +GP G G G +G
Sbjct: 382 NPGMKGEAGPTGARGPEGPQG 402
Score = 44.7 bits (104), Expect = 4e-04
Identities = 70/251 (27%), Positives = 87/251 (34%), Gaps = 31/251 (12%)
Query: 380 GPLEPAPSGDPEAPP--------------PGPLHSAFSSSRDLASSRDDFFRTKPRSASR 425
GP+ P S PE PP PG + A S K +
Sbjct: 246 GPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHK 305
Query: 426 PAAEPSGARG-----GESA--GLKGARSAEGPGGLEPGLEEHRRGPSGAAAF--LHEPPS 476
P G G GE+ G GA GP G+ PG E R GP GA H P
Sbjct: 306 GLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGM-PG-ERGRLGPQGAPGQRGAHGMPG 363
Query: 477 PPPPFDHYLGHKGAAEGKTPDFLLSQSVDQLARPPS--LGQAGQLIFCGSIDH--LKDNV 532
P P LG G++ + ++ AR P GQ G+ G + L +
Sbjct: 364 KPGPMGP-LGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAI 422
Query: 533 YRNVMPTLVIPAHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGP 592
+ P P G G+AG P P T P R P DP P G +GP
Sbjct: 423 GTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPG-DPGVPGFKGEAGP 481
Query: 593 GGEGGGGGGEG 603
GE G G +G
Sbjct: 482 KGEPGPHGIQG 492
Score = 39.7 bits (91), Expect = 0.012
Identities = 75/260 (28%), Positives = 90/260 (34%), Gaps = 67/260 (25%)
Query: 380 GPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGE-- 437
GPL AP D PPG + R +P S P + S G+
Sbjct: 588 GPLG-APGEDGRPGPPGSIG----------------IRGQPGSMGLPGPKGSSGDPGKPG 630
Query: 438 ---SAGLKGARSAEGPGGL--------EPGL--EEHRRGPSGAAAFLHEPPSPPPPFDHY 484
+AG+ G R A G G PGL E +GP G F P P PP
Sbjct: 631 EAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPP---- 686
Query: 485 LGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPA 544
EG P Q V P G G L G + N P +
Sbjct: 687 ------GEGGKPG---DQGV-----PGDPGAVGPLGPRGE----RGNPGERGEPGI---- 724
Query: 545 HYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQ-MPGHSG----PGGEGGGG 599
L GE G AG G P P+G +PGP+ P Q MPG G PG +G G
Sbjct: 725 --TGLPGEKGMAG-GHGPDGPKG-SPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRG 780
Query: 600 GGEGWGAGRAAPVSGSVTIP 619
G GA A G+ +P
Sbjct: 781 GIGEKGAEGTAGNDGARGLP 800
Score = 32.3 bits (72), Expect = 1.8
Identities = 63/229 (27%), Positives = 74/229 (32%), Gaps = 34/229 (14%)
Query: 394 PPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEP--SGARGGESA----GLKGARSA 447
PPG S + +F R + P P +G RG G +G R
Sbjct: 88 PPGECCPVCSQTP--GGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGE 145
Query: 448 EGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDFLLSQSVDQL 507
GP G R GP G EP P P A G P D L
Sbjct: 146 RGPKG--------RPGPRGPQGIDGEPGVPGQP---------GAPGP-PGHPSHPGPDGL 187
Query: 508 ARPPSLGQAG--QLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVGDEPAPP 565
+RP S AG + GS L V P P G AG G EP P
Sbjct: 188 SRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRG--PQGLQGQQGGAGPTGPPGEPGDP 245
Query: 566 EGTAPGPARAFPQPDPQRPQM---PGHSGPGGEGGGGGGEGWGAGRAAP 611
P +R P+ P +P PG +G GE G G G AP
Sbjct: 246 GPMGPIGSRG-PEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAP 293
Score = 31.2 bits (69), Expect = 4.1
Identities = 54/189 (28%), Positives = 61/189 (32%), Gaps = 42/189 (22%)
Query: 420 PRSASRPAAE-PSGARGGESAGLKGARSAEGPGGLEPGLEEHRR----GPSGAAAFLHEP 474
P SA R P+GA G AG G EGP GL H R GP+G P
Sbjct: 911 PGSAGRVGPPGPAGAPG--PAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAG-------P 961
Query: 475 PSPPPPFDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYR 534
P P G G PD P G GQ G +
Sbjct: 962 PGGPGD----KGDPGEDGQPGPD----------GPPGPAGTTGQRGIVG----MPGQRGE 1003
Query: 535 NVMPTLVIPAHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGG 594
MP L PA G+ G G + PP P P P +P G GP G
Sbjct: 1004 RGMPGLPGPAG---TPGKVGPTGATGDKGPPGPVGP-PGSNGPVGEP------GPEGPAG 1053
Query: 595 EGGGGGGEG 603
G G +G
Sbjct: 1054 NDGTPGRDG 1062
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 45.8 bits (107), Expect = 2e-04
Identities = 93/329 (28%), Positives = 102/329 (31%), Gaps = 88/329 (26%)
Query: 403 SSSRDLASSRDDFFRTKPRSASRPAAEPSGARG-----GESAGLKGA---RSAEG-PGGL 453
S LA+S PR+ AA +GA G G AG GA AEG PG
Sbjct: 28 SLESQLAASAAHHHHLAPRTPEVRAAA-AGALGNHVVSGSPAGAAGAGPAAPAEGAPGAA 86
Query: 454 EPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSL 513
R P G PPSP P G P RPP
Sbjct: 87 PEPPPAGRARPGGGGPQRPGPPSPRRPL--------VPAGPAPP-------AAKLRPPPE 131
Query: 514 GQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVGDEPAPPEGTAPGPA 573
G AG C + A V G E AG PA P G A A
Sbjct: 132 GSAGS---CAPVP----------------AAAAVAAGPEPAPAG----PAKPAGPAALAA 168
Query: 574 RAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAGRAAPVSGSVTIPVLFNESTMAQLNGE 633
RA P P P GPG G G G+ G G A ++GS L N A
Sbjct: 169 RAGPGPGP---------GPGPGPGPGPGKPAGPGAAQTLNGSA---ALLNSHHAAAPAVS 216
Query: 634 LQALTEKKLLELGVKPHPRAWFVSLDGRSNSQVRHSYIDLQAGGGARSTDASLDSGVDVH 693
L LL L P P A + I GA + A
Sbjct: 217 LVNNGPAALLPL---PKPAA-------------PGTVIQTPPFVGAAAPPA--------- 251
Query: 694 EARPARRRPAREERERAPPAAPPPPPAPP 722
PA P AP AAPPPPP P
Sbjct: 252 ---PAAPSPPAAPAPAAPAAAPPPPPPAP 277
Score = 38.5 bits (88), Expect = 0.026
Identities = 99/392 (25%), Positives = 124/392 (31%), Gaps = 61/392 (15%)
Query: 381 PLEPAPSGDPEAPPPGPLHSAFSSSRDLA--SSRDDFFRTKPRSASRPAAE----PSGAR 434
P E AP PE PP G + S R P + PAA+ P G+
Sbjct: 78 PAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLV---PAGPAPPAAKLRPPPEGSA 134
Query: 435 GGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGK 494
G + A A GP G + GP+ AA P P P G G G
Sbjct: 135 GSCAPVPAAAAVAAGPEPAPAGPAKPA-GPAALAARAGPGPGPGPGPGPGPG-PGKPAGP 192
Query: 495 TPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAG 554
L+ S L + A L+ G L +P P ++ G
Sbjct: 193 GAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLP-------LPKPAAPGTVIQTPPFVG 245
Query: 555 AAGVGDEPAPPEGTAPGPA--RAFPQPDPQRP----QMPGHSG---------PGGEGGGG 599
AA AP AP PA A P P P P + PGH P
Sbjct: 246 AAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQN 305
Query: 600 GGEGWGAGRAAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPHPRAWFVSLD 659
GG A AP +G A ++G+ GVK V
Sbjct: 306 GGSAGAAPAPAPAAGG-----------PAGVSGQPGPGAAAAAPAPGVKAESPKRVV--- 351
Query: 660 GRSNSQVRHSYIDLQAGGGARSTDASLDSGVDVHEARPARRRPAREERERAPPAAPPPPP 719
Q A G ST AS+ G + A P+ PA PP AP P
Sbjct: 352 -----QAAPPAAQTLAASGPASTAASMVIGPTMQGALPS---PA-----AVPPPAPGTPT 398
Query: 720 APPRLALSEDTEPSSSESRTGLCSPEDNSLTP 751
P+ A T+ S S + T S +LTP
Sbjct: 399 GLPKGAAGAVTQ-SLSRTPTATTSGIRATLTP 429
>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
sapiens]
Length = 1650
Score = 45.8 bits (107), Expect = 2e-04
Identities = 76/262 (29%), Positives = 84/262 (32%), Gaps = 75/262 (28%)
Query: 383 EPAPSGDPEAP-PPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGESA-- 439
E SG P P PPGP + DD + P P GG
Sbjct: 1152 EKGESGQPGEPGPPGPK----------GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQD 1201
Query: 440 GLKGARSAEG----PGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGA----- 490
G KG R +G PG P E GP G P+ P + G KGA
Sbjct: 1202 GAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRG-----PAGSPGSEGRQGGKGAKGDPG 1256
Query: 491 ---AEGKT-------------PDFL--LSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNV 532
A GKT PD L L SV Q RP + GQAG
Sbjct: 1257 AIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGP-------------- 1302
Query: 533 YRNVMPTLVIPAHYVRLGGEAGAAGVGDEPA------PPEGTAPGPARAFPQPDPQRPQ- 585
P V P L G+AGA G P PP R P P Q
Sbjct: 1303 -----PGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQK 1357
Query: 586 ----MPGHSGPGGEGGGGGGEG 603
+PG SGP G GG G G
Sbjct: 1358 GEMGIPGASGPIGPGGPPGLPG 1379
Score = 42.4 bits (98), Expect = 0.002
Identities = 77/277 (27%), Positives = 89/277 (32%), Gaps = 71/277 (25%)
Query: 358 GPSDGNKRDQATS-MSQLHLICGGPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFF 416
GP + QA + + Q L GP P P G PGPL S L D
Sbjct: 378 GPVVAAQEAQAQAILQQARLALRGP--PGPMG--YTGRPGPLGQP--GSPGLKGESGDLG 431
Query: 417 RTKPRSASRPAAEPSGARGGESAGLKGARSAEGPGGLE--------PGL--EEHRRGPSG 466
PR P A AG GAR G G++ PGL E+ RG +G
Sbjct: 432 PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTG 491
Query: 467 AAAFLHEPPSPPPPF-----DHYLGHKGAAEGKTPDFLLSQSVDQLARPPSL-GQAGQLI 520
A P PP D +G +G P LL PP + G G
Sbjct: 492 AQGL----PGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK-----GPPGIPGPPGVRG 542
Query: 521 FCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVGDEPAPP--EGTA-----PGPA 573
G G G+ G EP PP +GT PGP
Sbjct: 543 MDGP-------------------------QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQ 577
Query: 574 RAF-------PQPDPQRPQMPGHSGPGGEGGGGGGEG 603
A PQ P P MPG GP G G G G
Sbjct: 578 GAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPG 614
Score = 40.4 bits (93), Expect = 0.007
Identities = 54/177 (30%), Positives = 66/177 (37%), Gaps = 31/177 (17%)
Query: 432 GARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHE-----PPSPPPPFDHYLG 486
GA+G E G +G GP GL+ GL GPSG + PP PP P G
Sbjct: 1052 GAKGDE--GTRGFNGPPGPIGLQ-GLP----GPSGEKGETGDVGPMGPPGPPGPRGP-AG 1103
Query: 487 HKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHY 546
GA + P V L P G+ G+ G P + P
Sbjct: 1104 PNGADGPQGPP----GGVGNLGPPGEKGEPGESGSPGIQGE----------PGVKGPRGE 1149
Query: 547 VRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEG 603
GE G +G EP PP P P+ +P PG GP GEGG G +G
Sbjct: 1150 ---RGEKGESGQPGEPGPPGPKGPTGDDG-PKGNPGPVGFPGDPGPPGEGGPRGQDG 1202
Score = 40.0 bits (92), Expect = 0.009
Identities = 57/193 (29%), Positives = 65/193 (33%), Gaps = 40/193 (20%)
Query: 417 RTKPRSASRPAAEPSGARGGESA----GLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLH 472
++ PR P P G RG A G KG +GP G P E GP G F
Sbjct: 747 KSGPRGERGPTG-PRGQRGPRGATGKSGAKGTSGGDGPHG--PPGERGLPGPQGPNGFPG 803
Query: 473 EPPSPPPPFDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNV 532
P PP GK D L P GQ G++ F G
Sbjct: 804 PKGPPGPP------------GK----------DGLPGHP--GQRGEVGFQGKTGPPGP-- 837
Query: 533 YRNVMPTLVIPAHYVRLGGEAGAAGVGDEPAPP-EGTAPGPA-RAFPQPDPQRPQMPGHS 590
P +V P G G G P PP E PG A + + DP P PG
Sbjct: 838 -----PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKD 892
Query: 591 GPGGEGGGGGGEG 603
GP G G G G
Sbjct: 893 GPAGLRGFPGERG 905
Score = 37.7 bits (86), Expect = 0.044
Identities = 73/269 (27%), Positives = 88/269 (32%), Gaps = 68/269 (25%)
Query: 383 EPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAE----PSGARGGES 438
+P P G P P L F R L P +A P + PSG G
Sbjct: 882 DPGPPGAPGKDGPAGLRG-FPGERGL-----------PGTAGGPGLKGNEGPSGPPG--P 927
Query: 439 AGLKGARSAEGPGG-LEPGLEEHRRGPSGAAAFLHEP----PSPPPPFDHYLGHKGAAEG 493
AG G R A G GG + P +GP GAA P P P D G G
Sbjct: 928 AGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP 987
Query: 494 KTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEA 553
P + + D+ +G GQ K N + P P V G+
Sbjct: 988 AGPPGVAGEDGDK----GEVGDPGQ-------KGTKGNKGEHGPPGPPGPIGPV---GQP 1033
Query: 554 GAAGVGDEPAP-----------PEGTA-----PGPA--RAFPQPDPQR-----------P 584
GAAG EP EGT PGP + P P ++ P
Sbjct: 1034 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPP 1093
Query: 585 QMPGHSGPGGEGGGGGGEG--WGAGRAAP 611
PG GP G G G +G G G P
Sbjct: 1094 GPPGPRGPAGPNGADGPQGPPGGVGNLGP 1122
Score = 32.3 bits (72), Expect = 1.8
Identities = 38/135 (28%), Positives = 51/135 (37%), Gaps = 21/135 (15%)
Query: 535 NVMPTLVIPAHYVR-LGGEAGAAGVGDE------PAPPEGTAP--GPARAFPQPDPQRPQ 585
+++P L AH R L GE G V + P PEG A GP P P
Sbjct: 280 SLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGD- 338
Query: 586 MPGHSGPGGEGGGGGGEGWGAGRAAPVSGSVTIPVLFNES------TMAQLNGELQALTE 639
PG GP G G G + G P S+ +P F +A + QA+ +
Sbjct: 339 -PGERGPPGRAGLPGSD----GAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQ 393
Query: 640 KKLLELGVKPHPRAW 654
+ L L P P +
Sbjct: 394 QARLALRGPPGPMGY 408
Score = 32.0 bits (71), Expect = 2.4
Identities = 54/180 (30%), Positives = 68/180 (37%), Gaps = 17/180 (9%)
Query: 428 AEPSGARGGESAGLKGARSAEGPGGLE--PGLEEHRRGPSGAAAFL-HEPPSPPPPFDHY 484
A G +G G GA +GP GL PG E G +G +E PS PP
Sbjct: 874 AGKEGTKG--DPGPPGAPGKDGPAGLRGFPG-ERGLPGTAGGPGLKGNEGPSGPPGPAGS 930
Query: 485 LGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHL-KDNVYRNVMPTLVIP 543
G +GAA P + Q P + G+ G G I +D V V L P
Sbjct: 931 PGERGAAGSGGPIGPPGRPGPQ-GPPGAAGEKGVPGEKGPIGPTGRDGVQGPV--GLPGP 987
Query: 544 AHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEG 603
A + GE G G +P +GT P P PG GP G+ G G +G
Sbjct: 988 AGPPGVAGEDGDKGEVGDPGQ-KGTKGNKGEHGP------PGPPGPIGPVGQPGAAGADG 1040
Score = 31.2 bits (69), Expect = 4.1
Identities = 22/63 (34%), Positives = 27/63 (42%), Gaps = 4/63 (6%)
Query: 549 LGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAGR 608
L GE+G G+ PP PGP PQ P+ G GP GE G G +G +
Sbjct: 516 LPGESGPRGLLGPKGPP--GIPGPPGVRGMDGPQGPK--GSLGPQGEPGPPGQQGTPGTQ 571
Query: 609 AAP 611
P
Sbjct: 572 GLP 574
Score = 30.0 bits (66), Expect = 9.2
Identities = 36/115 (31%), Positives = 50/115 (43%), Gaps = 18/115 (15%)
Query: 430 PSGARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPS---PPPPFDHYLG 486
P G G AG KGA+ A GPGG P E+ +GP G PP P P
Sbjct: 1374 PPGLPG--PAGPKGAKGATGPGG--PKGEKGVQGPPGHPG----PPGEVIQPLPIQMPKK 1425
Query: 487 HKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQL--IFCGSIDHLKDNVYRNVMPT 539
+ + +G L Q + + + G G L IF GS+D L++ + + PT
Sbjct: 1426 TRRSVDGSR----LMQEDEAIPTGGAPGSPGGLEEIF-GSLDSLREEIEQMRRPT 1475
>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
sapiens]
Length = 1629
Score = 45.8 bits (107), Expect = 2e-04
Identities = 76/262 (29%), Positives = 84/262 (32%), Gaps = 75/262 (28%)
Query: 383 EPAPSGDPEAP-PPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGESA-- 439
E SG P P PPGP + DD + P P GG
Sbjct: 1131 EKGESGQPGEPGPPGPK----------GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQD 1180
Query: 440 GLKGARSAEG----PGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGA----- 490
G KG R +G PG P E GP G P+ P + G KGA
Sbjct: 1181 GAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRG-----PAGSPGSEGRQGGKGAKGDPG 1235
Query: 491 ---AEGKT-------------PDFL--LSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNV 532
A GKT PD L L SV Q RP + GQAG
Sbjct: 1236 AIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGP-------------- 1281
Query: 533 YRNVMPTLVIPAHYVRLGGEAGAAGVGDEPA------PPEGTAPGPARAFPQPDPQRPQ- 585
P V P L G+AGA G P PP R P P Q
Sbjct: 1282 -----PGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQK 1336
Query: 586 ----MPGHSGPGGEGGGGGGEG 603
+PG SGP G GG G G
Sbjct: 1337 GEMGIPGASGPIGPGGPPGLPG 1358
Score = 42.4 bits (98), Expect = 0.002
Identities = 77/277 (27%), Positives = 89/277 (32%), Gaps = 71/277 (25%)
Query: 358 GPSDGNKRDQATS-MSQLHLICGGPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFF 416
GP + QA + + Q L GP P P G PGPL S L D
Sbjct: 357 GPVVAAQEAQAQAILQQARLALRGP--PGPMG--YTGRPGPLGQP--GSPGLKGESGDLG 410
Query: 417 RTKPRSASRPAAEPSGARGGESAGLKGARSAEGPGGLE--------PGL--EEHRRGPSG 466
PR P A AG GAR G G++ PGL E+ RG +G
Sbjct: 411 PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTG 470
Query: 467 AAAFLHEPPSPPPPF-----DHYLGHKGAAEGKTPDFLLSQSVDQLARPPSL-GQAGQLI 520
A P PP D +G +G P LL PP + G G
Sbjct: 471 AQGL----PGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK-----GPPGIPGPPGVRG 521
Query: 521 FCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVGDEPAPP--EGTA-----PGPA 573
G G G+ G EP PP +GT PGP
Sbjct: 522 MDGP-------------------------QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQ 556
Query: 574 RAF-------PQPDPQRPQMPGHSGPGGEGGGGGGEG 603
A PQ P P MPG GP G G G G
Sbjct: 557 GAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPG 593
Score = 40.4 bits (93), Expect = 0.007
Identities = 54/177 (30%), Positives = 66/177 (37%), Gaps = 31/177 (17%)
Query: 432 GARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHE-----PPSPPPPFDHYLG 486
GA+G E G +G GP GL+ GL GPSG + PP PP P G
Sbjct: 1031 GAKGDE--GTRGFNGPPGPIGLQ-GLP----GPSGEKGETGDVGPMGPPGPPGPRGP-AG 1082
Query: 487 HKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHY 546
GA + P V L P G+ G+ G P + P
Sbjct: 1083 PNGADGPQGPP----GGVGNLGPPGEKGEPGESGSPGIQGE----------PGVKGPRGE 1128
Query: 547 VRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEG 603
GE G +G EP PP P P+ +P PG GP GEGG G +G
Sbjct: 1129 ---RGEKGESGQPGEPGPPGPKGPTGDDG-PKGNPGPVGFPGDPGPPGEGGPRGQDG 1181
Score = 40.0 bits (92), Expect = 0.009
Identities = 57/193 (29%), Positives = 65/193 (33%), Gaps = 40/193 (20%)
Query: 417 RTKPRSASRPAAEPSGARGGESA----GLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLH 472
++ PR P P G RG A G KG +GP G P E GP G F
Sbjct: 726 KSGPRGERGPTG-PRGQRGPRGATGKSGAKGTSGGDGPHG--PPGERGLPGPQGPNGFPG 782
Query: 473 EPPSPPPPFDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNV 532
P PP GK D L P GQ G++ F G
Sbjct: 783 PKGPPGPP------------GK----------DGLPGHP--GQRGEVGFQGKTGPPGP-- 816
Query: 533 YRNVMPTLVIPAHYVRLGGEAGAAGVGDEPAPP-EGTAPGPA-RAFPQPDPQRPQMPGHS 590
P +V P G G G P PP E PG A + + DP P PG
Sbjct: 817 -----PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKD 871
Query: 591 GPGGEGGGGGGEG 603
GP G G G G
Sbjct: 872 GPAGLRGFPGERG 884
Score = 37.7 bits (86), Expect = 0.044
Identities = 73/269 (27%), Positives = 88/269 (32%), Gaps = 68/269 (25%)
Query: 383 EPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAE----PSGARGGES 438
+P P G P P L F R L P +A P + PSG G
Sbjct: 861 DPGPPGAPGKDGPAGLRG-FPGERGL-----------PGTAGGPGLKGNEGPSGPPG--P 906
Query: 439 AGLKGARSAEGPGG-LEPGLEEHRRGPSGAAAFLHEP----PSPPPPFDHYLGHKGAAEG 493
AG G R A G GG + P +GP GAA P P P D G G
Sbjct: 907 AGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP 966
Query: 494 KTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEA 553
P + + D+ +G GQ K N + P P V G+
Sbjct: 967 AGPPGVAGEDGDK----GEVGDPGQ-------KGTKGNKGEHGPPGPPGPIGPV---GQP 1012
Query: 554 GAAGVGDEPAP-----------PEGTA-----PGPA--RAFPQPDPQR-----------P 584
GAAG EP EGT PGP + P P ++ P
Sbjct: 1013 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPP 1072
Query: 585 QMPGHSGPGGEGGGGGGEG--WGAGRAAP 611
PG GP G G G +G G G P
Sbjct: 1073 GPPGPRGPAGPNGADGPQGPPGGVGNLGP 1101
Score = 32.0 bits (71), Expect = 2.4
Identities = 54/180 (30%), Positives = 68/180 (37%), Gaps = 17/180 (9%)
Query: 428 AEPSGARGGESAGLKGARSAEGPGGLE--PGLEEHRRGPSGAAAFL-HEPPSPPPPFDHY 484
A G +G G GA +GP GL PG E G +G +E PS PP
Sbjct: 853 AGKEGTKG--DPGPPGAPGKDGPAGLRGFPG-ERGLPGTAGGPGLKGNEGPSGPPGPAGS 909
Query: 485 LGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHL-KDNVYRNVMPTLVIP 543
G +GAA P + Q P + G+ G G I +D V V L P
Sbjct: 910 PGERGAAGSGGPIGPPGRPGPQ-GPPGAAGEKGVPGEKGPIGPTGRDGVQGPV--GLPGP 966
Query: 544 AHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEG 603
A + GE G G +P +GT P P PG GP G+ G G +G
Sbjct: 967 AGPPGVAGEDGDKGEVGDPGQ-KGTKGNKGEHGP------PGPPGPIGPVGQPGAAGADG 1019
Score = 31.2 bits (69), Expect = 4.1
Identities = 22/63 (34%), Positives = 27/63 (42%), Gaps = 4/63 (6%)
Query: 549 LGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAGR 608
L GE+G G+ PP PGP PQ P+ G GP GE G G +G +
Sbjct: 495 LPGESGPRGLLGPKGPP--GIPGPPGVRGMDGPQGPK--GSLGPQGEPGPPGQQGTPGTQ 550
Query: 609 AAP 611
P
Sbjct: 551 GLP 553
Score = 30.0 bits (66), Expect = 9.2
Identities = 36/115 (31%), Positives = 50/115 (43%), Gaps = 18/115 (15%)
Query: 430 PSGARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPS---PPPPFDHYLG 486
P G G AG KGA+ A GPGG P E+ +GP G PP P P
Sbjct: 1353 PPGLPG--PAGPKGAKGATGPGG--PKGEKGVQGPPGHPG----PPGEVIQPLPIQMPKK 1404
Query: 487 HKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQL--IFCGSIDHLKDNVYRNVMPT 539
+ + +G L Q + + + G G L IF GS+D L++ + + PT
Sbjct: 1405 TRRSVDGSR----LMQEDEAIPTGGAPGSPGGLEEIF-GSLDSLREEIEQMRRPT 1454
>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
sapiens]
Length = 1736
Score = 45.8 bits (107), Expect = 2e-04
Identities = 76/262 (29%), Positives = 84/262 (32%), Gaps = 75/262 (28%)
Query: 383 EPAPSGDPEAP-PPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGESA-- 439
E SG P P PPGP + DD + P P GG
Sbjct: 1238 EKGESGQPGEPGPPGPK----------GPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQD 1287
Query: 440 GLKGARSAEG----PGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGA----- 490
G KG R +G PG P E GP G P+ P + G KGA
Sbjct: 1288 GAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRG-----PAGSPGSEGRQGGKGAKGDPG 1342
Query: 491 ---AEGKT-------------PDFL--LSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNV 532
A GKT PD L L SV Q RP + GQAG
Sbjct: 1343 AIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGP-------------- 1388
Query: 533 YRNVMPTLVIPAHYVRLGGEAGAAGVGDEPA------PPEGTAPGPARAFPQPDPQRPQ- 585
P V P L G+AGA G P PP R P P Q
Sbjct: 1389 -----PGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQK 1443
Query: 586 ----MPGHSGPGGEGGGGGGEG 603
+PG SGP G GG G G
Sbjct: 1444 GEMGIPGASGPIGPGGPPGLPG 1465
Score = 42.4 bits (98), Expect = 0.002
Identities = 77/277 (27%), Positives = 89/277 (32%), Gaps = 71/277 (25%)
Query: 358 GPSDGNKRDQATS-MSQLHLICGGPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFF 416
GP + QA + + Q L GP P P G PGPL S L D
Sbjct: 464 GPVVAAQEAQAQAILQQARLALRGP--PGPMG--YTGRPGPLGQP--GSPGLKGESGDLG 517
Query: 417 RTKPRSASRPAAEPSGARGGESAGLKGARSAEGPGGLE--------PGL--EEHRRGPSG 466
PR P A AG GAR G G++ PGL E+ RG +G
Sbjct: 518 PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTG 577
Query: 467 AAAFLHEPPSPPPPF-----DHYLGHKGAAEGKTPDFLLSQSVDQLARPPSL-GQAGQLI 520
A P PP D +G +G P LL PP + G G
Sbjct: 578 AQGL----PGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK-----GPPGIPGPPGVRG 628
Query: 521 FCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVGDEPAPP--EGTA-----PGPA 573
G G G+ G EP PP +GT PGP
Sbjct: 629 MDGP-------------------------QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQ 663
Query: 574 RAF-------PQPDPQRPQMPGHSGPGGEGGGGGGEG 603
A PQ P P MPG GP G G G G
Sbjct: 664 GAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPG 700
Score = 40.4 bits (93), Expect = 0.007
Identities = 54/177 (30%), Positives = 66/177 (37%), Gaps = 31/177 (17%)
Query: 432 GARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHE-----PPSPPPPFDHYLG 486
GA+G E G +G GP GL+ GL GPSG + PP PP P G
Sbjct: 1138 GAKGDE--GTRGFNGPPGPIGLQ-GLP----GPSGEKGETGDVGPMGPPGPPGPRGP-AG 1189
Query: 487 HKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHY 546
GA + P V L P G+ G+ G P + P
Sbjct: 1190 PNGADGPQGPP----GGVGNLGPPGEKGEPGESGSPGIQGE----------PGVKGPRGE 1235
Query: 547 VRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEG 603
GE G +G EP PP P P+ +P PG GP GEGG G +G
Sbjct: 1236 ---RGEKGESGQPGEPGPPGPKGPTGDDG-PKGNPGPVGFPGDPGPPGEGGPRGQDG 1288
Score = 40.0 bits (92), Expect = 0.009
Identities = 57/193 (29%), Positives = 65/193 (33%), Gaps = 40/193 (20%)
Query: 417 RTKPRSASRPAAEPSGARGGESA----GLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLH 472
++ PR P P G RG A G KG +GP G P E GP G F
Sbjct: 833 KSGPRGERGPTG-PRGQRGPRGATGKSGAKGTSGGDGPHG--PPGERGLPGPQGPNGFPG 889
Query: 473 EPPSPPPPFDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNV 532
P PP GK D L P GQ G++ F G
Sbjct: 890 PKGPPGPP------------GK----------DGLPGHP--GQRGEVGFQGKTGPPGP-- 923
Query: 533 YRNVMPTLVIPAHYVRLGGEAGAAGVGDEPAPP-EGTAPGPA-RAFPQPDPQRPQMPGHS 590
P +V P G G G P PP E PG A + + DP P PG
Sbjct: 924 -----PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKD 978
Query: 591 GPGGEGGGGGGEG 603
GP G G G G
Sbjct: 979 GPAGLRGFPGERG 991
Score = 37.7 bits (86), Expect = 0.044
Identities = 73/269 (27%), Positives = 88/269 (32%), Gaps = 68/269 (25%)
Query: 383 EPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAE----PSGARGGES 438
+P P G P P L F R L P +A P + PSG G
Sbjct: 968 DPGPPGAPGKDGPAGLRG-FPGERGL-----------PGTAGGPGLKGNEGPSGPPG--P 1013
Query: 439 AGLKGARSAEGPGG-LEPGLEEHRRGPSGAAAFLHEP----PSPPPPFDHYLGHKGAAEG 493
AG G R A G GG + P +GP GAA P P P D G G
Sbjct: 1014 AGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP 1073
Query: 494 KTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEA 553
P + + D+ +G GQ K N + P P V G+
Sbjct: 1074 AGPPGVAGEDGDK----GEVGDPGQ-------KGTKGNKGEHGPPGPPGPIGPV---GQP 1119
Query: 554 GAAGVGDEPAP-----------PEGTA-----PGPA--RAFPQPDPQR-----------P 584
GAAG EP EGT PGP + P P ++ P
Sbjct: 1120 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPP 1179
Query: 585 QMPGHSGPGGEGGGGGGEG--WGAGRAAP 611
PG GP G G G +G G G P
Sbjct: 1180 GPPGPRGPAGPNGADGPQGPPGGVGNLGP 1208
Score = 32.0 bits (71), Expect = 2.4
Identities = 54/180 (30%), Positives = 68/180 (37%), Gaps = 17/180 (9%)
Query: 428 AEPSGARGGESAGLKGARSAEGPGGLE--PGLEEHRRGPSGAAAFL-HEPPSPPPPFDHY 484
A G +G G GA +GP GL PG E G +G +E PS PP
Sbjct: 960 AGKEGTKG--DPGPPGAPGKDGPAGLRGFPG-ERGLPGTAGGPGLKGNEGPSGPPGPAGS 1016
Query: 485 LGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHL-KDNVYRNVMPTLVIP 543
G +GAA P + Q P + G+ G G I +D V V L P
Sbjct: 1017 PGERGAAGSGGPIGPPGRPGPQ-GPPGAAGEKGVPGEKGPIGPTGRDGVQGPV--GLPGP 1073
Query: 544 AHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEG 603
A + GE G G +P +GT P P PG GP G+ G G +G
Sbjct: 1074 AGPPGVAGEDGDKGEVGDPGQ-KGTKGNKGEHGP------PGPPGPIGPVGQPGAAGADG 1126
Score = 31.2 bits (69), Expect = 4.1
Identities = 22/63 (34%), Positives = 27/63 (42%), Gaps = 4/63 (6%)
Query: 549 LGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAGR 608
L GE+G G+ PP PGP PQ P+ G GP GE G G +G +
Sbjct: 602 LPGESGPRGLLGPKGPP--GIPGPPGVRGMDGPQGPK--GSLGPQGEPGPPGQQGTPGTQ 657
Query: 609 AAP 611
P
Sbjct: 658 GLP 660
Score = 30.0 bits (66), Expect = 9.2
Identities = 36/115 (31%), Positives = 50/115 (43%), Gaps = 18/115 (15%)
Query: 430 PSGARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPS---PPPPFDHYLG 486
P G G AG KGA+ A GPGG P E+ +GP G PP P P
Sbjct: 1460 PPGLPG--PAGPKGAKGATGPGG--PKGEKGVQGPPGHPG----PPGEVIQPLPIQMPKK 1511
Query: 487 HKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQL--IFCGSIDHLKDNVYRNVMPT 539
+ + +G L Q + + + G G L IF GS+D L++ + + PT
Sbjct: 1512 TRRSVDGSR----LMQEDEAIPTGGAPGSPGGLEEIF-GSLDSLREEIEQMRRPT 1561
>gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 45.8 bits (107), Expect = 2e-04
Identities = 78/318 (24%), Positives = 109/318 (34%), Gaps = 60/318 (18%)
Query: 324 ALALLVLILLCLLIYYCRRRCLKPRQQHRKLQLSGPSDGNKRDQATSMSQLHL-----IC 378
+L LL + L C C PR H +S + QA Q+++ +
Sbjct: 323 SLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMT 382
Query: 379 GGPLEPAPSGDPEAPPPGP--LHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGG 436
G P P+ + EAPPPGP S SS ++ SS + A P P A
Sbjct: 383 GNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAE--------GAPPPGPAPPPATSH 434
Query: 437 ESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTP 496
+S E + +++ P G + P PP GH + P
Sbjct: 435 PRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPP-------GHGQTLGQQVP 487
Query: 497 DFLLSQSVDQLARP------------PSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPA 544
F + + +ARP P + Q G+ L V V L+ P
Sbjct: 488 GFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPV 547
Query: 545 HYVRLGGEAGAAGVGDEPAP--------------PEGTAP-GPARAFPQPDP-----QRP 584
+ G G+ PAP G AP GPA+ P P P Q
Sbjct: 548 LVAQ-----GTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFS 602
Query: 585 QMPGH-SGPGGEGGGGGG 601
Q+ G+ GP G G GG G
Sbjct: 603 QLLGNLLGPAGPGAGGSG 620
Score = 39.3 bits (90), Expect = 0.015
Identities = 78/274 (28%), Positives = 103/274 (37%), Gaps = 29/274 (10%)
Query: 551 GEAGAAGVGD---EPAPPEGTAPGPAR-AFPQPDPQRPQMPGHSGPGGEGG-GGGGEGWG 605
G G G G + P TAP A P P RP PG GP G G G G
Sbjct: 471 GPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPG--GPPVSGTLQGAGLGTN 528
Query: 606 AGRAAPVSGSV----TIPVLFNESTM------AQLNGELQALTEKKLLELGVKPHPRAWF 655
A A VSG V PVL + T A A T G P A
Sbjct: 529 ASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQP 588
Query: 656 VSLDGRSNSQVRHSYI--DL--QAGGGARSTDASLDSGVDVHEARPARRRPARE---ERE 708
S + ++ S + +L AG GA + + + PA + + +
Sbjct: 589 PPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQ 648
Query: 709 RAPPAAPPPPPAPPRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDE--VAAPEGRAATV 766
APP PPPPP PP A + T P G SP L L E + +G +++
Sbjct: 649 TAPPPPPPPPPPPP--APEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSL 706
Query: 767 PRGRGRSRGDSSRSSASELRRDSLTSPEDELGAE 800
G +R SS S A+ ++R S +S E GA+
Sbjct: 707 LGSLG-ARAGSSESIAAFIQRLSGSSNIFEPGAD 739
Score = 33.5 bits (75), Expect = 0.83
Identities = 45/182 (24%), Positives = 57/182 (31%), Gaps = 57/182 (31%)
Query: 427 AAEPSGARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLG 486
A P+ A SAG + GP P G A +PP P P
Sbjct: 557 APPPAPATASASAGTTNTATTAGPA------------PGGPA----QPPPTPQP------ 594
Query: 487 HKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHY 546
D SQ + L P G G + +I T+ +P
Sbjct: 595 -------SMADLQFSQLLGNLLGPAGPGAGGSGVASPTI-------------TVAMP--- 631
Query: 547 VRLGGEAGAAGVGD-----EPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGG 601
G A G+ D + APP P P P P P++ MP P G G GG
Sbjct: 632 ---GVPAFLQGMTDFLQATQTAPPPPPPPPP----PPPAPEQQTMPPPGSPSGGAGSPGG 684
Query: 602 EG 603
G
Sbjct: 685 LG 686
>gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 45.8 bits (107), Expect = 2e-04
Identities = 78/318 (24%), Positives = 109/318 (34%), Gaps = 60/318 (18%)
Query: 324 ALALLVLILLCLLIYYCRRRCLKPRQQHRKLQLSGPSDGNKRDQATSMSQLHL-----IC 378
+L LL + L C C PR H +S + QA Q+++ +
Sbjct: 323 SLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMT 382
Query: 379 GGPLEPAPSGDPEAPPPGP--LHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGG 436
G P P+ + EAPPPGP S SS ++ SS + A P P A
Sbjct: 383 GNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAE--------GAPPPGPAPPPATSH 434
Query: 437 ESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTP 496
+S E + +++ P G + P PP GH + P
Sbjct: 435 PRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPP-------GHGQTLGQQVP 487
Query: 497 DFLLSQSVDQLARP------------PSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPA 544
F + + +ARP P + Q G+ L V V L+ P
Sbjct: 488 GFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPV 547
Query: 545 HYVRLGGEAGAAGVGDEPAP--------------PEGTAP-GPARAFPQPDP-----QRP 584
+ G G+ PAP G AP GPA+ P P P Q
Sbjct: 548 LVAQ-----GTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFS 602
Query: 585 QMPGH-SGPGGEGGGGGG 601
Q+ G+ GP G G GG G
Sbjct: 603 QLLGNLLGPAGPGAGGSG 620
Score = 39.3 bits (90), Expect = 0.015
Identities = 78/274 (28%), Positives = 103/274 (37%), Gaps = 29/274 (10%)
Query: 551 GEAGAAGVGD---EPAPPEGTAPGPAR-AFPQPDPQRPQMPGHSGPGGEGG-GGGGEGWG 605
G G G G + P TAP A P P RP PG GP G G G G
Sbjct: 471 GPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPG--GPPVSGTLQGAGLGTN 528
Query: 606 AGRAAPVSGSV----TIPVLFNESTM------AQLNGELQALTEKKLLELGVKPHPRAWF 655
A A VSG V PVL + T A A T G P A
Sbjct: 529 ASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQP 588
Query: 656 VSLDGRSNSQVRHSYI--DL--QAGGGARSTDASLDSGVDVHEARPARRRPARE---ERE 708
S + ++ S + +L AG GA + + + PA + + +
Sbjct: 589 PPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQ 648
Query: 709 RAPPAAPPPPPAPPRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDE--VAAPEGRAATV 766
APP PPPPP PP A + T P G SP L L E + +G +++
Sbjct: 649 TAPPPPPPPPPPPP--APEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSL 706
Query: 767 PRGRGRSRGDSSRSSASELRRDSLTSPEDELGAE 800
G +R SS S A+ ++R S +S E GA+
Sbjct: 707 LGSLG-ARAGSSESIAAFIQRLSGSSNIFEPGAD 739
Score = 33.5 bits (75), Expect = 0.83
Identities = 45/182 (24%), Positives = 57/182 (31%), Gaps = 57/182 (31%)
Query: 427 AAEPSGARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLG 486
A P+ A SAG + GP P G A +PP P P
Sbjct: 557 APPPAPATASASAGTTNTATTAGPA------------PGGPA----QPPPTPQP------ 594
Query: 487 HKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHY 546
D SQ + L P G G + +I T+ +P
Sbjct: 595 -------SMADLQFSQLLGNLLGPAGPGAGGSGVASPTI-------------TVAMP--- 631
Query: 547 VRLGGEAGAAGVGD-----EPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGG 601
G A G+ D + APP P P P P P++ MP P G G GG
Sbjct: 632 ---GVPAFLQGMTDFLQATQTAPPPPPPPPP----PPPAPEQQTMPPPGSPSGGAGSPGG 684
Query: 602 EG 603
G
Sbjct: 685 LG 686
>gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 45.8 bits (107), Expect = 2e-04
Identities = 78/318 (24%), Positives = 109/318 (34%), Gaps = 60/318 (18%)
Query: 324 ALALLVLILLCLLIYYCRRRCLKPRQQHRKLQLSGPSDGNKRDQATSMSQLHL-----IC 378
+L LL + L C C PR H +S + QA Q+++ +
Sbjct: 323 SLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMT 382
Query: 379 GGPLEPAPSGDPEAPPPGP--LHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGG 436
G P P+ + EAPPPGP S SS ++ SS + A P P A
Sbjct: 383 GNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAE--------GAPPPGPAPPPATSH 434
Query: 437 ESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTP 496
+S E + +++ P G + P PP GH + P
Sbjct: 435 PRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPP-------GHGQTLGQQVP 487
Query: 497 DFLLSQSVDQLARP------------PSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPA 544
F + + +ARP P + Q G+ L V V L+ P
Sbjct: 488 GFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPV 547
Query: 545 HYVRLGGEAGAAGVGDEPAP--------------PEGTAP-GPARAFPQPDP-----QRP 584
+ G G+ PAP G AP GPA+ P P P Q
Sbjct: 548 LVAQ-----GTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFS 602
Query: 585 QMPGH-SGPGGEGGGGGG 601
Q+ G+ GP G G GG G
Sbjct: 603 QLLGNLLGPAGPGAGGSG 620
Score = 39.3 bits (90), Expect = 0.015
Identities = 78/274 (28%), Positives = 103/274 (37%), Gaps = 29/274 (10%)
Query: 551 GEAGAAGVGD---EPAPPEGTAPGPAR-AFPQPDPQRPQMPGHSGPGGEGG-GGGGEGWG 605
G G G G + P TAP A P P RP PG GP G G G G
Sbjct: 471 GPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPG--GPPVSGTLQGAGLGTN 528
Query: 606 AGRAAPVSGSV----TIPVLFNESTM------AQLNGELQALTEKKLLELGVKPHPRAWF 655
A A VSG V PVL + T A A T G P A
Sbjct: 529 ASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQP 588
Query: 656 VSLDGRSNSQVRHSYI--DL--QAGGGARSTDASLDSGVDVHEARPARRRPARE---ERE 708
S + ++ S + +L AG GA + + + PA + + +
Sbjct: 589 PPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQ 648
Query: 709 RAPPAAPPPPPAPPRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDE--VAAPEGRAATV 766
APP PPPPP PP A + T P G SP L L E + +G +++
Sbjct: 649 TAPPPPPPPPPPPP--APEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSL 706
Query: 767 PRGRGRSRGDSSRSSASELRRDSLTSPEDELGAE 800
G +R SS S A+ ++R S +S E GA+
Sbjct: 707 LGSLG-ARAGSSESIAAFIQRLSGSSNIFEPGAD 739
Score = 33.5 bits (75), Expect = 0.83
Identities = 45/182 (24%), Positives = 57/182 (31%), Gaps = 57/182 (31%)
Query: 427 AAEPSGARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLG 486
A P+ A SAG + GP P G A +PP P P
Sbjct: 557 APPPAPATASASAGTTNTATTAGPA------------PGGPA----QPPPTPQP------ 594
Query: 487 HKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHY 546
D SQ + L P G G + +I T+ +P
Sbjct: 595 -------SMADLQFSQLLGNLLGPAGPGAGGSGVASPTI-------------TVAMP--- 631
Query: 547 VRLGGEAGAAGVGD-----EPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGG 601
G A G+ D + APP P P P P P++ MP P G G GG
Sbjct: 632 ---GVPAFLQGMTDFLQATQTAPPPPPPPPP----PPPAPEQQTMPPPGSPSGGAGSPGG 684
Query: 602 EG 603
G
Sbjct: 685 LG 686
>gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]
Length = 1132
Score = 45.8 bits (107), Expect = 2e-04
Identities = 78/318 (24%), Positives = 109/318 (34%), Gaps = 60/318 (18%)
Query: 324 ALALLVLILLCLLIYYCRRRCLKPRQQHRKLQLSGPSDGNKRDQATSMSQLHL-----IC 378
+L LL + L C C PR H +S + QA Q+++ +
Sbjct: 329 SLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMT 388
Query: 379 GGPLEPAPSGDPEAPPPGP--LHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGG 436
G P P+ + EAPPPGP S SS ++ SS + A P P A
Sbjct: 389 GNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAE--------GAPPPGPAPPPATSH 440
Query: 437 ESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTP 496
+S E + +++ P G + P PP GH + P
Sbjct: 441 PRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPP-------GHGQTLGQQVP 493
Query: 497 DFLLSQSVDQLARP------------PSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPA 544
F + + +ARP P + Q G+ L V V L+ P
Sbjct: 494 GFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPV 553
Query: 545 HYVRLGGEAGAAGVGDEPAP--------------PEGTAP-GPARAFPQPDP-----QRP 584
+ G G+ PAP G AP GPA+ P P P Q
Sbjct: 554 LVAQ-----GTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFS 608
Query: 585 QMPGH-SGPGGEGGGGGG 601
Q+ G+ GP G G GG G
Sbjct: 609 QLLGNLLGPAGPGAGGSG 626
Score = 39.3 bits (90), Expect = 0.015
Identities = 78/274 (28%), Positives = 103/274 (37%), Gaps = 29/274 (10%)
Query: 551 GEAGAAGVGD---EPAPPEGTAPGPAR-AFPQPDPQRPQMPGHSGPGGEGG-GGGGEGWG 605
G G G G + P TAP A P P RP PG GP G G G G
Sbjct: 477 GPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPG--GPPVSGTLQGAGLGTN 534
Query: 606 AGRAAPVSGSV----TIPVLFNESTM------AQLNGELQALTEKKLLELGVKPHPRAWF 655
A A VSG V PVL + T A A T G P A
Sbjct: 535 ASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQP 594
Query: 656 VSLDGRSNSQVRHSYI--DL--QAGGGARSTDASLDSGVDVHEARPARRRPARE---ERE 708
S + ++ S + +L AG GA + + + PA + + +
Sbjct: 595 PPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQ 654
Query: 709 RAPPAAPPPPPAPPRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDE--VAAPEGRAATV 766
APP PPPPP PP A + T P G SP L L E + +G +++
Sbjct: 655 TAPPPPPPPPPPPP--APEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSL 712
Query: 767 PRGRGRSRGDSSRSSASELRRDSLTSPEDELGAE 800
G +R SS S A+ ++R S +S E GA+
Sbjct: 713 LGSLG-ARAGSSESIAAFIQRLSGSSNIFEPGAD 745
Score = 33.5 bits (75), Expect = 0.83
Identities = 45/182 (24%), Positives = 57/182 (31%), Gaps = 57/182 (31%)
Query: 427 AAEPSGARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLG 486
A P+ A SAG + GP P G A +PP P P
Sbjct: 563 APPPAPATASASAGTTNTATTAGPA------------PGGPA----QPPPTPQP------ 600
Query: 487 HKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHY 546
D SQ + L P G G + +I T+ +P
Sbjct: 601 -------SMADLQFSQLLGNLLGPAGPGAGGSGVASPTI-------------TVAMP--- 637
Query: 547 VRLGGEAGAAGVGD-----EPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGG 601
G A G+ D + APP P P P P P++ MP P G G GG
Sbjct: 638 ---GVPAFLQGMTDFLQATQTAPPPPPPPPP----PPPAPEQQTMPPPGSPSGGAGSPGG 690
Query: 602 EG 603
G
Sbjct: 691 LG 692
>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
Length = 1690
Score = 45.8 bits (107), Expect = 2e-04
Identities = 76/266 (28%), Positives = 96/266 (36%), Gaps = 53/266 (19%)
Query: 379 GGPLEPAPSGDPEAP-PPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPS-GARG- 435
G P P P GD P PPGP R L F P +P AE GA+G
Sbjct: 885 GLPGIPGPFGDDGLPGPPGP-----KGPRGLPG-----FPGFPGERGKPGAEGCPGAKGE 934
Query: 436 -GESA--------GLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSP----PPPFD 482
GE GL+GA+ A GP G E G A + + +P PP D
Sbjct: 935 PGEKGMSGLPGDRGLRGAKGAIGPPGDE-----------GEMAIISQKGTPGEPGPPGDD 983
Query: 483 HYLGHKGAAEGKTPDFLLSQSVDQLARPPSL-----GQAGQLIFCGSIDHLKDNVYRNVM 537
+ G +G + TP + PP G+ GQ G R +
Sbjct: 984 GFPGERG--DKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFI 1041
Query: 538 PTLVIPAHYVRLG--GEAGAAGVGDEPAPPEGTAPGPARAF----PQPDPQRPQMPGHSG 591
+P G G G +G+ D P+G PA F P+ +P P PGH G
Sbjct: 1042 GFPGLPGDQGEPGSPGPPGFSGI-DGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFG 1100
Query: 592 PGGEGGGGGGEG--WGAGRAAPVSGS 615
GE G G +G GR P S
Sbjct: 1101 ASGEQGLPGIQGPRGSPGRPGPPGSS 1126
Score = 41.6 bits (96), Expect = 0.003
Identities = 63/254 (24%), Positives = 80/254 (31%), Gaps = 54/254 (21%)
Query: 379 GGPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAE-PSGARGGE 437
G P P SG P P + ++ + P P + PSG+ G
Sbjct: 1118 GRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLN 1177
Query: 438 SA-GLKGARSAEGPGGLE----------PGLEEHRRGPSGAAAFLHEPPSP--------P 478
GLKG + +G GL PGL+ R P PP P P
Sbjct: 1178 GLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGI---SPPGPRGKKGPPGP 1234
Query: 479 PPFDHYLGHKGAAEGKTPDFLLSQSVDQLARPPS----LGQAGQLIFCGSIDHLKDNVYR 534
P G GA G+ P + PP G G GS+D L+
Sbjct: 1235 PGSSGPPGPAGAT-GRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLR----- 1288
Query: 535 NVMPTLVIPAHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQ-----MPGH 589
GE G G+ P PP P + FP D + Q PG
Sbjct: 1289 ----------------GEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGP 1332
Query: 590 SGPGGEGGGGGGEG 603
GP G G G +G
Sbjct: 1333 QGPHGFPGPPGEKG 1346
Score = 32.7 bits (73), Expect = 1.4
Identities = 62/247 (25%), Positives = 82/247 (33%), Gaps = 59/247 (23%)
Query: 379 GGPLEPAPSGDPEAP-PPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGE 437
G P P G P P PPGP R KP + +G+RG
Sbjct: 113 GVPGFPGLDGIPGHPGPPGP-------------------RGKPGMSGH-----NGSRG-- 146
Query: 438 SAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFL-----------HEPPSPPPPFDHYLG 486
G G R A GPGG P +G G + F+ +P P P G
Sbjct: 147 DPGFPGGRGALGPGG--PLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAG 204
Query: 487 HKGAAEGKTPDFLLSQSVDQLARP-----PSLGQAGQLIFCGSIDHLKDNVYRNVMPTLV 541
G + L Q RP P +G GQ+ G + + PTL+
Sbjct: 205 GPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQ-----QGSPGPTLL 259
Query: 542 I-PAHYVRLGGEAGAAGVGDE---PAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGG 597
+ P + GE G G+ P PP A + +PG GP G+ G
Sbjct: 260 VEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKG-----IPGFPGPRGDPG 314
Query: 598 GGGGEGW 604
G G+
Sbjct: 315 SYGSPGF 321
Score = 30.0 bits (66), Expect = 9.2
Identities = 26/88 (29%), Positives = 32/88 (36%), Gaps = 20/88 (22%)
Query: 551 GEAGAAGVGDEPAPP---EGTAPGPARAFPQP----------------DPQRPQMPGHSG 591
G G AG +P PP E PG + FP P P P GH G
Sbjct: 587 GRDGHAGEKGDPGPPGDHEDATPG-GKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPG 645
Query: 592 PGGEGGGGGGEGWGAGRAAPVSGSVTIP 619
G G G +G + +S +VT P
Sbjct: 646 VPGHPGVRGPDGLKGQKGDTISCNVTYP 673
>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
sapiens]
Length = 1424
Score = 45.8 bits (107), Expect = 2e-04
Identities = 65/228 (28%), Positives = 76/228 (33%), Gaps = 44/228 (19%)
Query: 384 PAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAE-PSGARGGESAGLK 442
P P G P A PG + R P S P A P G G G+K
Sbjct: 1224 PGPPGLPGAIIPGQTGN----------------RGPPGSRGSPGAPGPPGPPGSHVIGIK 1267
Query: 443 GARSAEG-PGGLEPGLEEHRRGPSGAAAFLHEP----PSPPPPFDHYLGHKGAAEGKTPD 497
G + + G PG P GP G P P P F + G KG E P
Sbjct: 1268 GDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKG--EKGNPG 1325
Query: 498 FLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLG--GEAGA 555
FL S + P +G G G LK + +P G GE G
Sbjct: 1326 FLGS-----IGPPGPIGPKGPPGVRGDPGTLK---------IISLPGSPGPPGTPGEPGM 1371
Query: 556 AGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEG 603
G P PP P R P D + PG GP GE G G +G
Sbjct: 1372 QGEPGPPGPPGNLGPCGPRGKPGKDGK----PGTPGPAGEKGNKGSKG 1415
Score = 40.8 bits (94), Expect = 0.005
Identities = 53/184 (28%), Positives = 64/184 (34%), Gaps = 40/184 (21%)
Query: 437 ESAGLKGARSAEGPGGLE--PGLEEHRRGPSGAAAFLHEPPSPPP--PFDHY----LGHK 488
++ G G A GP GL PG GP G F P + P P H +GHK
Sbjct: 168 DAKGDPGLPGAPGPQGLPGPPGFPGPV-GPPGPPGFFGFPGAMGPRGPKGHMGERVIGHK 226
Query: 489 GAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVR 548
G + V L PP G G +I TL P +
Sbjct: 227 G-----------ERGVKGLTGPP--GPPGTVIV-----------------TLTGPDNRTD 256
Query: 549 LGGEAGAAGVGDEPAPPEGTA-PGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAG 607
L GE G G EP PP + PG + + P P + G G G G G EG
Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN 316
Query: 608 RAAP 611
R P
Sbjct: 317 RGFP 320
Score = 37.4 bits (85), Expect = 0.057
Identities = 46/174 (26%), Positives = 54/174 (31%), Gaps = 55/174 (31%)
Query: 440 GLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDFL 499
GLKG + GP G GP G P P G +G
Sbjct: 979 GLKGLKGLPGPAGPP--------GPRGDLGSTGNPGEP--------GLRG---------- 1012
Query: 500 LSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVG 559
+ S+ + P S G+ G L F G A L G G G
Sbjct: 1013 IPGSMGNMGMPGSKGKRGTLGFPGR-------------------AGRPGLPGIHGLQGDK 1053
Query: 560 DEPAPPEGTAPGPARAFPQP----------DPQRPQMPGHSGPGGEGGGGGGEG 603
EP EGT PGP P + +P PGH GP G G G G
Sbjct: 1054 GEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPG 1107
Score = 36.2 bits (82), Expect = 0.13
Identities = 71/276 (25%), Positives = 84/276 (30%), Gaps = 55/276 (19%)
Query: 379 GGPLEPAPSGDPEAP-------PPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPS 431
G P P P G P P PPGP FF R P
Sbjct: 174 GLPGAPGPQGLPGPPGFPGPVGPPGP---------------PGFFGFPGAMGPRG---PK 215
Query: 432 GARGGESAGLKGARSAEG-------PGGL-----EPGLEEHRRGPSGAAAFLHEPPSPPP 479
G G G KG R +G PG + P +G G + EP P P
Sbjct: 216 GHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGP 275
Query: 480 ---PFDHYLGHKGAAEGKTPDFLLSQSVDQLAR-PPSLGQAGQLIFCGSI--DHLKDNVY 533
P + Y KGA P D + P S G G F G + D +K
Sbjct: 276 SGLPGESYGSEKGAPGD--PGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG 333
Query: 534 RNVMPTLVIPAHYVRLGGEAGAAGVGDEPAPPEGTAP----GPARAFPQPDPQRPQM--- 586
P P Y E G G P P P GP P RP +
Sbjct: 334 DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393
Query: 587 ---PGHSGPGGEGGGGGGEGWGAGRAAPVSGSVTIP 619
PG G GE G G + G + +GS +P
Sbjct: 394 PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLP 429
Score = 35.8 bits (81), Expect = 0.17
Identities = 45/186 (24%), Positives = 65/186 (34%), Gaps = 23/186 (12%)
Query: 420 PRSASRPAAEPSGARGGES-AGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPP 478
P P + G RG GLKG++ G G + G +G+ P P
Sbjct: 377 PGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPG 436
Query: 479 PPFDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMP 538
PP D + P +L S + + P G+ G + C ++ +P
Sbjct: 437 PPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPK--GEPG--LLCTQCPYIPGPPGLPGLP 492
Query: 539 TLVIPAHYVR-LGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGG 597
L H V+ + G GAAG+ P P T P PG G G+ G
Sbjct: 493 GL----HGVKGIPGRQGAAGLKGSPGSPGNTG-------------LPGFPGFPGAQGDPG 535
Query: 598 GGGGEG 603
G +G
Sbjct: 536 LKGEKG 541
Score = 33.1 bits (74), Expect = 1.1
Identities = 49/168 (29%), Positives = 60/168 (35%), Gaps = 25/168 (14%)
Query: 449 GPGGLE--PGLEEHRR--GPSGAAAFLHEPPSPP----PPFDHYLGHKGAAEGKTPDFLL 500
GP GL PGL + G GAA P SP P F + G +G K
Sbjct: 484 GPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGET 543
Query: 501 SQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVGD 560
Q Q+ P G GQ G +D + +P P + L GE G G
Sbjct: 544 LQPEGQVGVPGDPGLRGQPGRKG-LDGIPGTPGVKGLPG---PKGELALSGEKGDQGPPG 599
Query: 561 EPAPPEGTAP----GPARAFPQPDPQ---------RPQMPGHSGPGGE 595
+P P P GP PQ +P P PG +GP GE
Sbjct: 600 DPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGE 647
Score = 33.1 bits (74), Expect = 1.1
Identities = 51/180 (28%), Positives = 64/180 (35%), Gaps = 32/180 (17%)
Query: 430 PSGARGGESAGLKGARSAEGPGGLEPGLEEHR--RGPSGAAAFLHEPPSPPPPFDHY-LG 486
P G G GL G +G G +PG H GP GA P P P H LG
Sbjct: 1066 PPGPTG--DPGLPGDMGKKGEMG-QPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLG 1122
Query: 487 HKGAAEGKTPDFLLSQSVDQLARPPSL-GQAGQLIFCGSIDHL--KDNVYRNVMPTLVIP 543
KG + L PP + G G F GS + + + R+ +P P
Sbjct: 1123 FKG--------------IKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG---P 1165
Query: 544 AHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEG 603
A GE G G+ P P G + P P +PG G G+ G G G
Sbjct: 1166 A------GEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTG 1219
Score = 31.2 bits (69), Expect = 4.1
Identities = 20/56 (35%), Positives = 21/56 (37%), Gaps = 3/56 (5%)
Query: 551 GEAGAAGVGDEPAPPEGTAPGPARAFPQP---DPQRPQMPGHSGPGGEGGGGGGEG 603
G G GV P PP P + P P P PGH GP G G G G
Sbjct: 625 GLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLG 680
>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
sapiens]
Length = 1494
Score = 45.8 bits (107), Expect = 2e-04
Identities = 65/228 (28%), Positives = 76/228 (33%), Gaps = 44/228 (19%)
Query: 384 PAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAE-PSGARGGESAGLK 442
P P G P A PG + R P S P A P G G G+K
Sbjct: 1224 PGPPGLPGAIIPGQTGN----------------RGPPGSRGSPGAPGPPGPPGSHVIGIK 1267
Query: 443 GARSAEG-PGGLEPGLEEHRRGPSGAAAFLHEP----PSPPPPFDHYLGHKGAAEGKTPD 497
G + + G PG P GP G P P P F + G KG E P
Sbjct: 1268 GDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKG--EKGNPG 1325
Query: 498 FLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLG--GEAGA 555
FL S + P +G G G LK + +P G GE G
Sbjct: 1326 FLGS-----IGPPGPIGPKGPPGVRGDPGTLK---------IISLPGSPGPPGTPGEPGM 1371
Query: 556 AGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEG 603
G P PP P R P D + PG GP GE G G +G
Sbjct: 1372 QGEPGPPGPPGNLGPCGPRGKPGKDGK----PGTPGPAGEKGNKGSKG 1415
Score = 40.8 bits (94), Expect = 0.005
Identities = 53/184 (28%), Positives = 64/184 (34%), Gaps = 40/184 (21%)
Query: 437 ESAGLKGARSAEGPGGLE--PGLEEHRRGPSGAAAFLHEPPSPPP--PFDHY----LGHK 488
++ G G A GP GL PG GP G F P + P P H +GHK
Sbjct: 168 DAKGDPGLPGAPGPQGLPGPPGFPGPV-GPPGPPGFFGFPGAMGPRGPKGHMGERVIGHK 226
Query: 489 GAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVR 548
G + V L PP G G +I TL P +
Sbjct: 227 G-----------ERGVKGLTGPP--GPPGTVIV-----------------TLTGPDNRTD 256
Query: 549 LGGEAGAAGVGDEPAPPEGTA-PGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAG 607
L GE G G EP PP + PG + + P P + G G G G G EG
Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN 316
Query: 608 RAAP 611
R P
Sbjct: 317 RGFP 320
Score = 37.4 bits (85), Expect = 0.057
Identities = 46/174 (26%), Positives = 54/174 (31%), Gaps = 55/174 (31%)
Query: 440 GLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDFL 499
GLKG + GP G GP G P P G +G
Sbjct: 979 GLKGLKGLPGPAGPP--------GPRGDLGSTGNPGEP--------GLRG---------- 1012
Query: 500 LSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVG 559
+ S+ + P S G+ G L F G A L G G G
Sbjct: 1013 IPGSMGNMGMPGSKGKRGTLGFPGR-------------------AGRPGLPGIHGLQGDK 1053
Query: 560 DEPAPPEGTAPGPARAFPQP----------DPQRPQMPGHSGPGGEGGGGGGEG 603
EP EGT PGP P + +P PGH GP G G G G
Sbjct: 1054 GEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPG 1107
Score = 36.2 bits (82), Expect = 0.13
Identities = 71/276 (25%), Positives = 84/276 (30%), Gaps = 55/276 (19%)
Query: 379 GGPLEPAPSGDPEAP-------PPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPS 431
G P P P G P P PPGP FF R P
Sbjct: 174 GLPGAPGPQGLPGPPGFPGPVGPPGP---------------PGFFGFPGAMGPRG---PK 215
Query: 432 GARGGESAGLKGARSAEG-------PGGL-----EPGLEEHRRGPSGAAAFLHEPPSPPP 479
G G G KG R +G PG + P +G G + EP P P
Sbjct: 216 GHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGP 275
Query: 480 ---PFDHYLGHKGAAEGKTPDFLLSQSVDQLAR-PPSLGQAGQLIFCGSI--DHLKDNVY 533
P + Y KGA P D + P S G G F G + D +K
Sbjct: 276 SGLPGESYGSEKGAPGD--PGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG 333
Query: 534 RNVMPTLVIPAHYVRLGGEAGAAGVGDEPAPPEGTAP----GPARAFPQPDPQRPQM--- 586
P P Y E G G P P P GP P RP +
Sbjct: 334 DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393
Query: 587 ---PGHSGPGGEGGGGGGEGWGAGRAAPVSGSVTIP 619
PG G GE G G + G + +GS +P
Sbjct: 394 PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLP 429
Score = 35.8 bits (81), Expect = 0.17
Identities = 45/186 (24%), Positives = 65/186 (34%), Gaps = 23/186 (12%)
Query: 420 PRSASRPAAEPSGARGGES-AGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPP 478
P P + G RG GLKG++ G G + G +G+ P P
Sbjct: 377 PGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPG 436
Query: 479 PPFDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMP 538
PP D + P +L S + + P G+ G + C ++ +P
Sbjct: 437 PPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPK--GEPG--LLCTQCPYIPGPPGLPGLP 492
Query: 539 TLVIPAHYVR-LGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGG 597
L H V+ + G GAAG+ P P T P PG G G+ G
Sbjct: 493 GL----HGVKGIPGRQGAAGLKGSPGSPGNTG-------------LPGFPGFPGAQGDPG 535
Query: 598 GGGGEG 603
G +G
Sbjct: 536 LKGEKG 541
Score = 33.1 bits (74), Expect = 1.1
Identities = 49/168 (29%), Positives = 60/168 (35%), Gaps = 25/168 (14%)
Query: 449 GPGGLE--PGLEEHRR--GPSGAAAFLHEPPSPP----PPFDHYLGHKGAAEGKTPDFLL 500
GP GL PGL + G GAA P SP P F + G +G K
Sbjct: 484 GPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGET 543
Query: 501 SQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVGD 560
Q Q+ P G GQ G +D + +P P + L GE G G
Sbjct: 544 LQPEGQVGVPGDPGLRGQPGRKG-LDGIPGTPGVKGLPG---PKGELALSGEKGDQGPPG 599
Query: 561 EPAPPEGTAP----GPARAFPQPDPQ---------RPQMPGHSGPGGE 595
+P P P GP PQ +P P PG +GP GE
Sbjct: 600 DPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGE 647
Score = 33.1 bits (74), Expect = 1.1
Identities = 51/180 (28%), Positives = 64/180 (35%), Gaps = 32/180 (17%)
Query: 430 PSGARGGESAGLKGARSAEGPGGLEPGLEEHR--RGPSGAAAFLHEPPSPPPPFDHY-LG 486
P G G GL G +G G +PG H GP GA P P P H LG
Sbjct: 1066 PPGPTG--DPGLPGDMGKKGEMG-QPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLG 1122
Query: 487 HKGAAEGKTPDFLLSQSVDQLARPPSL-GQAGQLIFCGSIDHL--KDNVYRNVMPTLVIP 543
KG + L PP + G G F GS + + + R+ +P P
Sbjct: 1123 FKG--------------IKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG---P 1165
Query: 544 AHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEG 603
A GE G G+ P P G + P P +PG G G+ G G G
Sbjct: 1166 A------GEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTG 1219
Score = 31.2 bits (69), Expect = 4.1
Identities = 20/56 (35%), Positives = 21/56 (37%), Gaps = 3/56 (5%)
Query: 551 GEAGAAGVGDEPAPPEGTAPGPARAFPQP---DPQRPQMPGHSGPGGEGGGGGGEG 603
G G GV P PP P + P P P PGH GP G G G G
Sbjct: 625 GLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLG 680
>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
sapiens]
Length = 1637
Score = 45.8 bits (107), Expect = 2e-04
Identities = 65/228 (28%), Positives = 76/228 (33%), Gaps = 44/228 (19%)
Query: 384 PAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAE-PSGARGGESAGLK 442
P P G P A PG + R P S P A P G G G+K
Sbjct: 1224 PGPPGLPGAIIPGQTGN----------------RGPPGSRGSPGAPGPPGPPGSHVIGIK 1267
Query: 443 GARSAEG-PGGLEPGLEEHRRGPSGAAAFLHEP----PSPPPPFDHYLGHKGAAEGKTPD 497
G + + G PG P GP G P P P F + G KG E P
Sbjct: 1268 GDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKG--EKGNPG 1325
Query: 498 FLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLG--GEAGA 555
FL S + P +G G G LK + +P G GE G
Sbjct: 1326 FLGS-----IGPPGPIGPKGPPGVRGDPGTLK---------IISLPGSPGPPGTPGEPGM 1371
Query: 556 AGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEG 603
G P PP P R P D + PG GP GE G G +G
Sbjct: 1372 QGEPGPPGPPGNLGPCGPRGKPGKDGK----PGTPGPAGEKGNKGSKG 1415
Score = 40.8 bits (94), Expect = 0.005
Identities = 53/184 (28%), Positives = 64/184 (34%), Gaps = 40/184 (21%)
Query: 437 ESAGLKGARSAEGPGGLE--PGLEEHRRGPSGAAAFLHEPPSPPP--PFDHY----LGHK 488
++ G G A GP GL PG GP G F P + P P H +GHK
Sbjct: 168 DAKGDPGLPGAPGPQGLPGPPGFPGPV-GPPGPPGFFGFPGAMGPRGPKGHMGERVIGHK 226
Query: 489 GAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVR 548
G + V L PP G G +I TL P +
Sbjct: 227 G-----------ERGVKGLTGPP--GPPGTVIV-----------------TLTGPDNRTD 256
Query: 549 LGGEAGAAGVGDEPAPPEGTA-PGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAG 607
L GE G G EP PP + PG + + P P + G G G G G EG
Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN 316
Query: 608 RAAP 611
R P
Sbjct: 317 RGFP 320
Score = 37.4 bits (85), Expect = 0.057
Identities = 46/174 (26%), Positives = 54/174 (31%), Gaps = 55/174 (31%)
Query: 440 GLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDFL 499
GLKG + GP G GP G P P G +G
Sbjct: 979 GLKGLKGLPGPAGPP--------GPRGDLGSTGNPGEP--------GLRG---------- 1012
Query: 500 LSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVG 559
+ S+ + P S G+ G L F G A L G G G
Sbjct: 1013 IPGSMGNMGMPGSKGKRGTLGFPGR-------------------AGRPGLPGIHGLQGDK 1053
Query: 560 DEPAPPEGTAPGPARAFPQP----------DPQRPQMPGHSGPGGEGGGGGGEG 603
EP EGT PGP P + +P PGH GP G G G G
Sbjct: 1054 GEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPG 1107
Score = 36.2 bits (82), Expect = 0.13
Identities = 71/276 (25%), Positives = 84/276 (30%), Gaps = 55/276 (19%)
Query: 379 GGPLEPAPSGDPEAP-------PPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPS 431
G P P P G P P PPGP FF R P
Sbjct: 174 GLPGAPGPQGLPGPPGFPGPVGPPGP---------------PGFFGFPGAMGPRG---PK 215
Query: 432 GARGGESAGLKGARSAEG-------PGGL-----EPGLEEHRRGPSGAAAFLHEPPSPPP 479
G G G KG R +G PG + P +G G + EP P P
Sbjct: 216 GHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGP 275
Query: 480 ---PFDHYLGHKGAAEGKTPDFLLSQSVDQLAR-PPSLGQAGQLIFCGSI--DHLKDNVY 533
P + Y KGA P D + P S G G F G + D +K
Sbjct: 276 SGLPGESYGSEKGAPGD--PGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG 333
Query: 534 RNVMPTLVIPAHYVRLGGEAGAAGVGDEPAPPEGTAP----GPARAFPQPDPQRPQM--- 586
P P Y E G G P P P GP P RP +
Sbjct: 334 DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393
Query: 587 ---PGHSGPGGEGGGGGGEGWGAGRAAPVSGSVTIP 619
PG G GE G G + G + +GS +P
Sbjct: 394 PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLP 429
Score = 35.8 bits (81), Expect = 0.17
Identities = 45/186 (24%), Positives = 65/186 (34%), Gaps = 23/186 (12%)
Query: 420 PRSASRPAAEPSGARGGES-AGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPP 478
P P + G RG GLKG++ G G + G +G+ P P
Sbjct: 377 PGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPG 436
Query: 479 PPFDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMP 538
PP D + P +L S + + P G+ G + C ++ +P
Sbjct: 437 PPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPK--GEPG--LLCTQCPYIPGPPGLPGLP 492
Query: 539 TLVIPAHYVR-LGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGG 597
L H V+ + G GAAG+ P P T P PG G G+ G
Sbjct: 493 GL----HGVKGIPGRQGAAGLKGSPGSPGNTG-------------LPGFPGFPGAQGDPG 535
Query: 598 GGGGEG 603
G +G
Sbjct: 536 LKGEKG 541
Score = 33.1 bits (74), Expect = 1.1
Identities = 49/168 (29%), Positives = 60/168 (35%), Gaps = 25/168 (14%)
Query: 449 GPGGLE--PGLEEHRR--GPSGAAAFLHEPPSPP----PPFDHYLGHKGAAEGKTPDFLL 500
GP GL PGL + G GAA P SP P F + G +G K
Sbjct: 484 GPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGET 543
Query: 501 SQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVGD 560
Q Q+ P G GQ G +D + +P P + L GE G G
Sbjct: 544 LQPEGQVGVPGDPGLRGQPGRKG-LDGIPGTPGVKGLPG---PKGELALSGEKGDQGPPG 599
Query: 561 EPAPPEGTAP----GPARAFPQPDPQ---------RPQMPGHSGPGGE 595
+P P P GP PQ +P P PG +GP GE
Sbjct: 600 DPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGE 647
Score = 33.1 bits (74), Expect = 1.1
Identities = 51/180 (28%), Positives = 64/180 (35%), Gaps = 32/180 (17%)
Query: 430 PSGARGGESAGLKGARSAEGPGGLEPGLEEHR--RGPSGAAAFLHEPPSPPPPFDHY-LG 486
P G G GL G +G G +PG H GP GA P P P H LG
Sbjct: 1066 PPGPTG--DPGLPGDMGKKGEMG-QPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLG 1122
Query: 487 HKGAAEGKTPDFLLSQSVDQLARPPSL-GQAGQLIFCGSIDHL--KDNVYRNVMPTLVIP 543
KG + L PP + G G F GS + + + R+ +P P
Sbjct: 1123 FKG--------------IKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG---P 1165
Query: 544 AHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEG 603
A GE G G+ P P G + P P +PG G G+ G G G
Sbjct: 1166 A------GEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTG 1219
Score = 31.2 bits (69), Expect = 4.1
Identities = 20/56 (35%), Positives = 21/56 (37%), Gaps = 3/56 (5%)
Query: 551 GEAGAAGVGDEPAPPEGTAPGPARAFPQP---DPQRPQMPGHSGPGGEGGGGGGEG 603
G G GV P PP P + P P P PGH GP G G G G
Sbjct: 625 GLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLG 680
>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
sapiens]
Length = 1670
Score = 45.8 bits (107), Expect = 2e-04
Identities = 65/228 (28%), Positives = 76/228 (33%), Gaps = 44/228 (19%)
Query: 384 PAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAE-PSGARGGESAGLK 442
P P G P A PG + R P S P A P G G G+K
Sbjct: 1224 PGPPGLPGAIIPGQTGN----------------RGPPGSRGSPGAPGPPGPPGSHVIGIK 1267
Query: 443 GARSAEG-PGGLEPGLEEHRRGPSGAAAFLHEP----PSPPPPFDHYLGHKGAAEGKTPD 497
G + + G PG P GP G P P P F + G KG E P
Sbjct: 1268 GDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKG--EKGNPG 1325
Query: 498 FLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLG--GEAGA 555
FL S + P +G G G LK + +P G GE G
Sbjct: 1326 FLGS-----IGPPGPIGPKGPPGVRGDPGTLK---------IISLPGSPGPPGTPGEPGM 1371
Query: 556 AGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEG 603
G P PP P R P D + PG GP GE G G +G
Sbjct: 1372 QGEPGPPGPPGNLGPCGPRGKPGKDGK----PGTPGPAGEKGNKGSKG 1415
Score = 40.8 bits (94), Expect = 0.005
Identities = 53/184 (28%), Positives = 64/184 (34%), Gaps = 40/184 (21%)
Query: 437 ESAGLKGARSAEGPGGLE--PGLEEHRRGPSGAAAFLHEPPSPPP--PFDHY----LGHK 488
++ G G A GP GL PG GP G F P + P P H +GHK
Sbjct: 168 DAKGDPGLPGAPGPQGLPGPPGFPGPV-GPPGPPGFFGFPGAMGPRGPKGHMGERVIGHK 226
Query: 489 GAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVR 548
G + V L PP G G +I TL P +
Sbjct: 227 G-----------ERGVKGLTGPP--GPPGTVIV-----------------TLTGPDNRTD 256
Query: 549 LGGEAGAAGVGDEPAPPEGTA-PGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAG 607
L GE G G EP PP + PG + + P P + G G G G G EG
Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN 316
Query: 608 RAAP 611
R P
Sbjct: 317 RGFP 320
Score = 37.4 bits (85), Expect = 0.057
Identities = 46/174 (26%), Positives = 54/174 (31%), Gaps = 55/174 (31%)
Query: 440 GLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDFL 499
GLKG + GP G GP G P P G +G
Sbjct: 979 GLKGLKGLPGPAGPP--------GPRGDLGSTGNPGEP--------GLRG---------- 1012
Query: 500 LSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVG 559
+ S+ + P S G+ G L F G A L G G G
Sbjct: 1013 IPGSMGNMGMPGSKGKRGTLGFPGR-------------------AGRPGLPGIHGLQGDK 1053
Query: 560 DEPAPPEGTAPGPARAFPQP----------DPQRPQMPGHSGPGGEGGGGGGEG 603
EP EGT PGP P + +P PGH GP G G G G
Sbjct: 1054 GEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPG 1107
Score = 36.2 bits (82), Expect = 0.13
Identities = 71/276 (25%), Positives = 84/276 (30%), Gaps = 55/276 (19%)
Query: 379 GGPLEPAPSGDPEAP-------PPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPS 431
G P P P G P P PPGP FF R P
Sbjct: 174 GLPGAPGPQGLPGPPGFPGPVGPPGP---------------PGFFGFPGAMGPRG---PK 215
Query: 432 GARGGESAGLKGARSAEG-------PGGL-----EPGLEEHRRGPSGAAAFLHEPPSPPP 479
G G G KG R +G PG + P +G G + EP P P
Sbjct: 216 GHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGP 275
Query: 480 ---PFDHYLGHKGAAEGKTPDFLLSQSVDQLAR-PPSLGQAGQLIFCGSI--DHLKDNVY 533
P + Y KGA P D + P S G G F G + D +K
Sbjct: 276 SGLPGESYGSEKGAPGD--PGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG 333
Query: 534 RNVMPTLVIPAHYVRLGGEAGAAGVGDEPAPPEGTAP----GPARAFPQPDPQRPQM--- 586
P P Y E G G P P P GP P RP +
Sbjct: 334 DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393
Query: 587 ---PGHSGPGGEGGGGGGEGWGAGRAAPVSGSVTIP 619
PG G GE G G + G + +GS +P
Sbjct: 394 PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLP 429
Score = 35.8 bits (81), Expect = 0.17
Identities = 45/186 (24%), Positives = 65/186 (34%), Gaps = 23/186 (12%)
Query: 420 PRSASRPAAEPSGARGGES-AGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPP 478
P P + G RG GLKG++ G G + G +G+ P P
Sbjct: 377 PGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPG 436
Query: 479 PPFDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMP 538
PP D + P +L S + + P G+ G + C ++ +P
Sbjct: 437 PPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPK--GEPG--LLCTQCPYIPGPPGLPGLP 492
Query: 539 TLVIPAHYVR-LGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGG 597
L H V+ + G GAAG+ P P T P PG G G+ G
Sbjct: 493 GL----HGVKGIPGRQGAAGLKGSPGSPGNTG-------------LPGFPGFPGAQGDPG 535
Query: 598 GGGGEG 603
G +G
Sbjct: 536 LKGEKG 541
Score = 33.1 bits (74), Expect = 1.1
Identities = 49/168 (29%), Positives = 60/168 (35%), Gaps = 25/168 (14%)
Query: 449 GPGGLE--PGLEEHRR--GPSGAAAFLHEPPSPP----PPFDHYLGHKGAAEGKTPDFLL 500
GP GL PGL + G GAA P SP P F + G +G K
Sbjct: 484 GPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGET 543
Query: 501 SQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVGD 560
Q Q+ P G GQ G +D + +P P + L GE G G
Sbjct: 544 LQPEGQVGVPGDPGLRGQPGRKG-LDGIPGTPGVKGLPG---PKGELALSGEKGDQGPPG 599
Query: 561 EPAPPEGTAP----GPARAFPQPDPQ---------RPQMPGHSGPGGE 595
+P P P GP PQ +P P PG +GP GE
Sbjct: 600 DPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGE 647
Score = 33.1 bits (74), Expect = 1.1
Identities = 51/180 (28%), Positives = 64/180 (35%), Gaps = 32/180 (17%)
Query: 430 PSGARGGESAGLKGARSAEGPGGLEPGLEEHR--RGPSGAAAFLHEPPSPPPPFDHY-LG 486
P G G GL G +G G +PG H GP GA P P P H LG
Sbjct: 1066 PPGPTG--DPGLPGDMGKKGEMG-QPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLG 1122
Query: 487 HKGAAEGKTPDFLLSQSVDQLARPPSL-GQAGQLIFCGSIDHL--KDNVYRNVMPTLVIP 543
KG + L PP + G G F GS + + + R+ +P P
Sbjct: 1123 FKG--------------IKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG---P 1165
Query: 544 AHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEG 603
A GE G G+ P P G + P P +PG G G+ G G G
Sbjct: 1166 A------GEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTG 1219
Score = 31.2 bits (69), Expect = 4.1
Identities = 20/56 (35%), Positives = 21/56 (37%), Gaps = 3/56 (5%)
Query: 551 GEAGAAGVGDEPAPPEGTAPGPARAFPQP---DPQRPQMPGHSGPGGEGGGGGGEG 603
G G GV P PP P + P P P PGH GP G G G G
Sbjct: 625 GLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLG 680
>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
potassium channel 4 [Homo sapiens]
Length = 1203
Score = 45.4 bits (106), Expect = 2e-04
Identities = 61/213 (28%), Positives = 74/213 (34%), Gaps = 63/213 (29%)
Query: 378 CGGPLEPAPSGDPEAPPP---GPLHSAFSSSRDLASSRDDFFRT--KPRSASRPAAEPSG 432
CG P P PS A G H A S SS D T +P + S AA+PS
Sbjct: 887 CGSPSAPTPSAGVAATTIAGFGHFHKALGGS---LSSSDSPLLTPLQPGARSPQAAQPSP 943
Query: 433 ARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAE 492
A G GL GL EH FL PPS P
Sbjct: 944 APPGARGGL--------------GLPEH---------FLPPPPSSRSP------------ 968
Query: 493 GKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGE 552
S S QL +PP G+ + G + + + P+LV G
Sbjct: 969 --------SSSPGQLGQPP--GELSLGLATGPLSTPETPPRQPEPPSLVA-------GAS 1011
Query: 553 AGAAGVGDEPA---PPEGTAPGPARAFPQPDPQ 582
GA+ VG P P G +PGP R FP P+
Sbjct: 1012 GGASPVGFTPRGGLSPPGHSPGPPRTFPSAPPR 1044
Score = 37.0 bits (84), Expect = 0.075
Identities = 65/243 (26%), Positives = 81/243 (33%), Gaps = 26/243 (10%)
Query: 375 HLICGGPLEPAPSGDPE--APPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSG 432
H + P +PS P PPG L S LA+ T PR P+ +G
Sbjct: 957 HFLPPPPSSRSPSSSPGQLGQPPGEL------SLGLATGPLSTPETPPRQPEPPSLV-AG 1009
Query: 433 ARGGESAGLKGARSAEGPGGLEPGLEEHRRGPS------GAAAFLHEPP--SPPPPFDHY 484
A GG S R P G PG R PS G+ L PP SPPPP
Sbjct: 1010 ASGGASPVGFTPRGGLSPPGHSPG--PPRTFPSAPPRASGSHGSLLLPPASSPPPP---Q 1064
Query: 485 LGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPA 544
+ + TP L A P+L Q G + H ++ + P
Sbjct: 1065 VPQRRGTPPLTPGRLTQDLKLISASQPALPQDGAQTLRRASPHSSGE---SMAAFPLFPR 1121
Query: 545 HYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGW 604
GG + G+G P P G PG P+ P S G GG
Sbjct: 1122 AGGGSGGSGSSGGLGP-PGRPYGAIPGQHVTLPRKTSSGSLPPPLSLFGARATSSGGPPL 1180
Query: 605 GAG 607
AG
Sbjct: 1181 TAG 1183
Score = 31.6 bits (70), Expect = 3.1
Identities = 42/156 (26%), Positives = 56/156 (35%), Gaps = 31/156 (19%)
Query: 602 EGWGAGRAAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELGVK----PHPRAWFVS 657
EG G GR P S+ + L + S A G TE + LG P A S
Sbjct: 35 EGAG-GRQDPSRRSIRLRPLPSPSPSAAAGG-----TESRSSALGAADSEGPARGAGKSS 88
Query: 658 LDGRSNSQVRHSYIDLQAGGGARSTDASLDSGVDVHEARPARR----------------- 700
+G + R S L + GG S S +H++ RR
Sbjct: 89 TNGDCR-RFRGSLASLGSRGGGSGGTGSGSSHGHLHDSAEERRLIAEGDASPGEDRTPPG 147
Query: 701 ---RPAREERERAPPAAPPPPPAPPRLALSEDTEPS 733
P R P A+PPPP PP+ A + +PS
Sbjct: 148 LAAEPERPGASAQPAASPPPPQQPPQPASASCEQPS 183
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.134 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,500,063
Number of Sequences: 37866
Number of extensions: 2601994
Number of successful extensions: 35452
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 383
Number of HSP's successfully gapped in prelim test: 968
Number of HSP's that attempted gapping in prelim test: 21863
Number of HSP's gapped (non-prelim): 11343
length of query: 826
length of database: 18,247,518
effective HSP length: 111
effective length of query: 715
effective length of database: 14,044,392
effective search space: 10041740280
effective search space used: 10041740280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.