Search of human proteins with 22218351

Search of human proteins with 22218351

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22218351 protease inhibitor WAP9 [Homo sapiens]
         (89 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22218351 protease inhibitor WAP9 [Homo sapiens]                    203   3e-53
gi|22218355 WAP four-disulfide core domain 11 precursor [Homo sa...    69   6e-13
gi|21703706 WAP four-disulfide core domain 10A precursor [Homo s...    43   5e-05
gi|26006869 WAP four-disulfide core domain 10B isoform a precurs...    40   5e-04
gi|26006867 WAP four-disulfide core domain 10B isoform b [Homo s...    33   0.048
gi|32307109 WAP four-disulfide core domain 3 precursor [Homo sap...    30   0.53 
gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens]           29   0.91 
gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP...    27   2.6  
gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP...    27   2.6  
gi|77812684 inorganic pyrophosphatase 2 isoform 5 precursor [Hom...    27   2.6  
gi|77812682 inorganic pyrophosphatase 2 isoform 4 precursor [Hom...    27   2.6  
gi|77812680 inorganic pyrophosphatase 2 isoform 3 precursor [Hom...    27   2.6  
gi|77812678 inorganic pyrophosphatase 2 isoform 2 precursor [Hom...    27   2.6  
gi|29171702 inorganic pyrophosphatase 2 isoform 1 precursor [Hom...    27   2.6  
gi|25188181 WAP four-disulfide core domain 13 precursor [Homo sa...    27   4.5  
gi|4501897 activin A receptor, type IIA precursor [Homo sapiens]       26   5.9  
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa...    26   5.9  
gi|157743245 WD repeat domain 43 [Homo sapiens]                        26   5.9  
gi|4757886 pituitary tumor-transforming gene 1 protein-interacti...    26   5.9  

>gi|22218351 protease inhibitor WAP9 [Homo sapiens]
          Length = 89

 Score =  203 bits (516), Expect = 3e-53
 Identities = 89/89 (100%), Positives = 89/89 (100%)

Query: 1  MKPWILLLVMFISGVVMLLPVLGSFWNKDPFLDMIRETEQCWVQPPYKYCEKRCTKIMTC 60
          MKPWILLLVMFISGVVMLLPVLGSFWNKDPFLDMIRETEQCWVQPPYKYCEKRCTKIMTC
Sbjct: 1  MKPWILLLVMFISGVVMLLPVLGSFWNKDPFLDMIRETEQCWVQPPYKYCEKRCTKIMTC 60

Query: 61 VRPNHTCCWTYCGNICLDNEEPLKSMLNP 89
          VRPNHTCCWTYCGNICLDNEEPLKSMLNP
Sbjct: 61 VRPNHTCCWTYCGNICLDNEEPLKSMLNP 89


>gi|22218355 WAP four-disulfide core domain 11 precursor [Homo
          sapiens]
          Length = 87

 Score = 69.3 bits (168), Expect = 6e-13
 Identities = 36/81 (44%), Positives = 44/81 (54%), Gaps = 3/81 (3%)

Query: 1  MKPWILLLVMFISGVVMLLPVLGSFWNKDPFLDMIRETEQCWVQPPYKYCEKRCTKIMTC 60
          MK WI +L+ F   V  LL VLG    K  +       E+CW +P  K C  +C+K   C
Sbjct: 5  MKLWIPMLMTFFCTV--LLSVLGEM-RKKRYDRKELLLEECWGKPNVKECTNKCSKAFRC 61

Query: 61 VRPNHTCCWTYCGNICLDNEE 81
             N+TCCWTYCGNIC  N E
Sbjct: 62 KDKNYTCCWTYCGNICWINVE 82


>gi|21703706 WAP four-disulfide core domain 10A precursor [Homo
          sapiens]
          Length = 79

 Score = 43.1 bits (100), Expect = 5e-05
 Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 5/79 (6%)

Query: 1  MKPWILLLVMFISGVVMLLPVLGSFWNKDPF--LDMIRETEQCWVQPPYKYCEKRCTKIM 58
          M P  LL V+ +   V+LL   G + +K       +  E + C  QP    C+  C    
Sbjct: 1  MAPQTLLPVLVLC--VLLLQAQGGYRDKKRMQKTQLSPEIKVCQQQPKLYLCKHLCESHR 58

Query: 59 TCVRPNHTCCWTYCGNICL 77
           C + N+ CC TYCGN+C+
Sbjct: 59 DC-QANNICCSTYCGNVCM 76


>gi|26006869 WAP four-disulfide core domain 10B isoform a
          precursor [Homo sapiens]
          Length = 73

 Score = 39.7 bits (91), Expect = 5e-04
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 7/77 (9%)

Query: 1  MKPWILLLVMFISGVVMLLPVLGSFWNKDPFLDMIRETEQCWVQPPYKYCEKRCTKIMTC 60
          M P  LLLV+ +   V+LL   G + +K      ++  + C  +P    C   C+    C
Sbjct: 1  MAPQTLLLVLVLC--VLLLQAQGGYRDKM----RMQRIKVCEKRPSIDLCIHHCSYFQKC 54

Query: 61 VRPNHTCCWTYCGNICL 77
             N  CC  +CGNIC+
Sbjct: 55 -ETNKICCSAFCGNICM 70


>gi|26006867 WAP four-disulfide core domain 10B isoform b [Homo
          sapiens]
          Length = 89

 Score = 33.1 bits (74), Expect = 0.048
 Identities = 13/37 (35%), Positives = 17/37 (45%), Gaps = 1/37 (2%)

Query: 41 CWVQPPYKYCEKRCTKIMTCVRPNHTCCWTYCGNICL 77
          C  +P    C   C+    C   N  CC  +CGNIC+
Sbjct: 51 CEKRPSIDLCIHHCSYFQKC-ETNKICCSAFCGNICM 86


>gi|32307109 WAP four-disulfide core domain 3 precursor [Homo
           sapiens]
          Length = 231

 Score = 29.6 bits (65), Expect = 0.53
 Identities = 13/32 (40%), Positives = 17/32 (53%), Gaps = 1/32 (3%)

Query: 50  CEKRCTKIMTCVRPNHTCCWTYCGNICLDNEE 81
           CE+ C    +C +  H CC T CG  CL + E
Sbjct: 133 CEELCDGDASCPQ-GHKCCSTGCGRTCLGDIE 163



 Score = 27.3 bits (59), Expect = 2.6
 Identities = 14/35 (40%), Positives = 17/35 (48%), Gaps = 2/35 (5%)

Query: 45 PPYKY-CEKRCTKIMTCVRPNHTCCWTYCGNICLD 78
          PP+K  C++ C     C      CC T CG IC D
Sbjct: 34 PPHKNPCKELCQGDELCPA-EQKCCTTGCGRICRD 67


>gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens]
          Length = 721

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 17/55 (30%), Positives = 23/55 (41%), Gaps = 12/55 (21%)

Query: 28  KDPFLDMIRETEQCWVQPPY---KYCEKRCTKIMTCVRPNHTCCWTYCGNICLDN 79
           +DP  D    TE CW    +   KYC+  C         +HTC +    +  LDN
Sbjct: 411 EDPAFDTNYSTEPCWQYSDHHENKYCDLEC---------SHTCNYKTRSSSYLDN 456


>gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP
          domains 1 isoform 2 [Homo sapiens]
          Length = 117

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 13/33 (39%), Positives = 17/33 (51%), Gaps = 1/33 (3%)

Query: 54 CTKIMTCVRPNHTCCWTYCGNICLDNEEPLKSM 86
          CTK   C + N  CC   CG  CLD ++ +  M
Sbjct: 32 CTKDRQC-QDNKKCCVFSCGKKCLDLKQDVCEM 63


>gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP
          domains 1 isoform 1 precursor [Homo sapiens]
          Length = 133

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 13/33 (39%), Positives = 17/33 (51%), Gaps = 1/33 (3%)

Query: 54 CTKIMTCVRPNHTCCWTYCGNICLDNEEPLKSM 86
          CTK   C + N  CC   CG  CLD ++ +  M
Sbjct: 48 CTKDRQC-QDNKKCCVFSCGKKCLDLKQDVCEM 79


>gi|77812684 inorganic pyrophosphatase 2 isoform 5 precursor [Homo
           sapiens]
          Length = 316

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 15/44 (34%), Positives = 19/44 (43%), Gaps = 3/44 (6%)

Query: 23  GSFWNKDPFLDMIRETEQCWVQPPYKYCEK---RCTKIMTCVRP 63
           G F NK   L++I+ T QCW     K C      CT +     P
Sbjct: 238 GEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSP 281


>gi|77812682 inorganic pyrophosphatase 2 isoform 4 precursor [Homo
           sapiens]
          Length = 168

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 15/44 (34%), Positives = 19/44 (43%), Gaps = 3/44 (6%)

Query: 23  GSFWNKDPFLDMIRETEQCWVQPPYKYCEK---RCTKIMTCVRP 63
           G F NK   L++I+ T QCW     K C      CT +     P
Sbjct: 90  GEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSP 133


>gi|77812680 inorganic pyrophosphatase 2 isoform 3 precursor [Homo
           sapiens]
          Length = 232

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 15/44 (34%), Positives = 19/44 (43%), Gaps = 3/44 (6%)

Query: 23  GSFWNKDPFLDMIRETEQCWVQPPYKYCEK---RCTKIMTCVRP 63
           G F NK   L++I+ T QCW     K C      CT +     P
Sbjct: 154 GEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSP 197


>gi|77812678 inorganic pyrophosphatase 2 isoform 2 precursor [Homo
           sapiens]
          Length = 305

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 15/44 (34%), Positives = 19/44 (43%), Gaps = 3/44 (6%)

Query: 23  GSFWNKDPFLDMIRETEQCWVQPPYKYCEK---RCTKIMTCVRP 63
           G F NK   L++I+ T QCW     K C      CT +     P
Sbjct: 227 GEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSP 270


>gi|29171702 inorganic pyrophosphatase 2 isoform 1 precursor [Homo
           sapiens]
          Length = 334

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 15/44 (34%), Positives = 19/44 (43%), Gaps = 3/44 (6%)

Query: 23  GSFWNKDPFLDMIRETEQCWVQPPYKYCEK---RCTKIMTCVRP 63
           G F NK   L++I+ T QCW     K C      CT +     P
Sbjct: 256 GEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSP 299


>gi|25188181 WAP four-disulfide core domain 13 precursor [Homo
          sapiens]
          Length = 93

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 24/76 (31%), Positives = 32/76 (42%), Gaps = 6/76 (7%)

Query: 1  MKPWILLLVMFISGVVMLLPVLGSFWNKDPFLDMIRETEQCWVQPPYKYCEKRCTKIMTC 60
          MKP +L L   +   + L  V GS   K   L  I E   C   P  + C   CT    C
Sbjct: 1  MKP-VLPLQFLVVFCLALQLVPGS--PKQRVLKYILEPPPCISAP--ENCTHLCTMQEDC 55

Query: 61 VRPNHTCCWTYCGNIC 76
           +    CC ++CG +C
Sbjct: 56 EK-GFQCCSSFCGIVC 70


>gi|4501897 activin A receptor, type IIA precursor [Homo sapiens]
          Length = 513

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 11/24 (45%), Positives = 15/24 (62%), Gaps = 1/24 (4%)

Query: 20  PVLGSFWNKDPFLDMIRET-EQCW 42
           PVL  +W K   + M+ ET E+CW
Sbjct: 439 PVLRDYWQKHAGMAMLCETIEECW 462


>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
           sapiens]
          Length = 641

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 15/40 (37%), Positives = 17/40 (42%), Gaps = 2/40 (5%)

Query: 52  KRCTKIMTCVRPNHTC--CWTYCGNICLDNEEPLKSMLNP 89
           K C K  +  +  H C  C     N C DNE PL S   P
Sbjct: 582 KLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKP 621


>gi|157743245 WD repeat domain 43 [Homo sapiens]
          Length = 677

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 19/70 (27%), Positives = 31/70 (44%), Gaps = 14/70 (20%)

Query: 2   KPWILLLVMFISGVVMLLPVLGSFW----------NKDPFLDMIRETEQCWVQPPYKYCE 51
           KP  +L   F S  + LL V GS++          +++P + ++R+   CW        E
Sbjct: 331 KPIPILAAGFCSDKMSLLLVYGSWFQPTIERVALNSREPHMCLVRDISNCWAPK----VE 386

Query: 52  KRCTKIMTCV 61
              TK+ T V
Sbjct: 387 TAITKVRTPV 396


>gi|4757886 pituitary tumor-transforming gene 1
          protein-interacting protein precursor [Homo sapiens]
          Length = 180

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 14/46 (30%), Positives = 19/46 (41%), Gaps = 2/46 (4%)

Query: 44 QPPYKYCEKRCTKIMTCVRPNHTCCWTYCGNICLDNEEPLKSMLNP 89
          +PP   C +   K       N +C W      CLD   P+ S+L P
Sbjct: 34 EPPGAACSQNTNKTCEECLKNVSCLWCNTNKACLD--YPVTSVLPP 77


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.142    0.524 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,014,540
Number of Sequences: 37866
Number of extensions: 160622
Number of successful extensions: 460
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 448
Number of HSP's gapped (non-prelim): 21
length of query: 89
length of database: 18,247,518
effective HSP length: 61
effective length of query: 28
effective length of database: 15,937,692
effective search space: 446255376
effective search space used: 446255376
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.