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Search of human proteins with 221625401
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo
sapiens]
(1037 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap... 2122 0.0
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap... 2056 0.0
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi... 1398 0.0
gi|4758282 ephrin receptor EphA7 [Homo sapiens] 1313 0.0
gi|4758280 ephrin receptor EphA4 [Homo sapiens] 1305 0.0
gi|145312251 EPH receptor A6 isoform a [Homo sapiens] 1243 0.0
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi... 1212 0.0
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi... 1165 0.0
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap... 1164 0.0
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens] 1130 0.0
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] 1088 0.0
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 1015 0.0
gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens] 926 0.0
gi|32528301 EPH receptor B4 precursor [Homo sapiens] 917 0.0
gi|221316650 ephrin receptor EphA1 [Homo sapiens] 789 0.0
gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens] 756 0.0
gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo sapi... 737 0.0
gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo sapi... 555 e-158
gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens] 318 2e-86
gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens] 229 1e-59
gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ... 226 7e-59
gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is... 226 7e-59
gi|4503787 fyn-related kinase [Homo sapiens] 223 7e-58
gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens] 223 1e-57
gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens] 222 1e-57
gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens] 222 1e-57
gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens] 222 2e-57
gi|112789548 lymphocyte-specific protein tyrosine kinase precurs... 221 4e-57
gi|112789546 lymphocyte-specific protein tyrosine kinase precurs... 221 4e-57
gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sap... 220 5e-57
>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens]
Length = 1037
Score = 2122 bits (5499), Expect = 0.0
Identities = 1037/1037 (100%), Positives = 1037/1037 (100%)
Query: 1 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE 60
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
Sbjct: 1 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE 60
Query: 61 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN 120
VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
Sbjct: 61 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN 120
Query: 121 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD 180
EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
Sbjct: 121 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD 180
Query: 181 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL 240
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
Sbjct: 181 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL 240
Query: 241 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG 300
AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
Sbjct: 241 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG 300
Query: 301 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA 360
TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
Sbjct: 301 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA 360
Query: 361 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG 420
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
Sbjct: 361 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG 420
Query: 421 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI 480
LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
Sbjct: 421 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI 480
Query: 481 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI 540
AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
Sbjct: 481 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI 540
Query: 541 RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCE 600
RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCE
Sbjct: 541 RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCE 600
Query: 601 CGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN 660
CGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN
Sbjct: 601 CGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN 660
Query: 661 QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD 720
QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD
Sbjct: 661 QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD 720
Query: 721 FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM 780
FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM
Sbjct: 721 FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM 780
Query: 781 LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI 840
LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI
Sbjct: 781 LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI 840
Query: 841 PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP 900
PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP
Sbjct: 841 PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP 900
Query: 901 MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS 960
MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS
Sbjct: 901 MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS 960
Query: 961 PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM 1020
PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM
Sbjct: 961 PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM 1020
Query: 1021 NSLQEMKVQLVNGMVPL 1037
NSLQEMKVQLVNGMVPL
Sbjct: 1021 NSLQEMKVQLVNGMVPL 1037
>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens]
Length = 1015
Score = 2056 bits (5328), Expect = 0.0
Identities = 1014/1037 (97%), Positives = 1014/1037 (97%), Gaps = 22/1037 (2%)
Query: 1 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE 60
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
Sbjct: 1 MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE 60
Query: 61 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN 120
VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
Sbjct: 61 VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN 120
Query: 121 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD 180
EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
Sbjct: 121 EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD 180
Query: 181 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL 240
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
Sbjct: 181 ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL 240
Query: 241 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG 300
AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
Sbjct: 241 AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG 300
Query: 301 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA 360
TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
Sbjct: 301 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA 360
Query: 361 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG 420
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
Sbjct: 361 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG 420
Query: 421 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI 480
LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
Sbjct: 421 LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI 480
Query: 481 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI 540
AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
Sbjct: 481 AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI 540
Query: 541 RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCE 600
RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSG
Sbjct: 541 RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGR--- 597
Query: 601 CGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN 660
RCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN
Sbjct: 598 -------------------RCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN 638
Query: 661 QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD 720
QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD
Sbjct: 639 QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD 698
Query: 721 FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM 780
FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM
Sbjct: 699 FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM 758
Query: 781 LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI 840
LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI
Sbjct: 759 LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI 818
Query: 841 PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP 900
PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP
Sbjct: 819 PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP 878
Query: 901 MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS 960
MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS
Sbjct: 879 MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS 938
Query: 961 PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM 1020
PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM
Sbjct: 939 PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM 998
Query: 1021 NSLQEMKVQLVNGMVPL 1037
NSLQEMKVQLVNGMVPL
Sbjct: 999 NSLQEMKVQLVNGMVPL 1015
>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapiens]
Length = 983
Score = 1398 bits (3618), Expect = 0.0
Identities = 668/999 (66%), Positives = 819/999 (81%), Gaps = 30/999 (3%)
Query: 44 LLLCAALRT---LLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQ 100
LL C+ L + L+ PSNEVNLLDS+T+ G+LGWI++P +GWEEI VDE+Y PI TYQ
Sbjct: 10 LLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQ 69
Query: 101 VCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDD 160
VC VM+ +QNNWL T+W+ A +I++ELKFTLRDCNS+P LGTCKETFN+YY ESDD
Sbjct: 70 VCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDD 129
Query: 161 QNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGAC 220
+G +E+Q+ KIDTIAADESFT++DLGDR++KLNTE+R+VGP++KKGFYLAFQDVGAC
Sbjct: 130 DHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGAC 189
Query: 221 IALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEG 280
+ALVSVRVY+KKCP V++LA+FPDT+ DS L+EV GSCVN+S ++PP+M+CS EG
Sbjct: 190 VALVSVRVYFKKCPFTVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEG 248
Query: 281 EWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEK 340
EWLVPIGKC C AGYEE+ CQ CRPGF+KA C KCPPHS T E+ S +C CE
Sbjct: 249 EWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCEN 308
Query: 341 DYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNS 400
+YFR + DPP+MACTRPPS+PRN ISN+NETSV L+W P DTGGRKDV++ I CKKC
Sbjct: 309 NYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGW 368
Query: 401 HAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSV 460
+ CE C +VR+LPRQ GL NT+V + DLLAHTNYTFEI+AVNGVS+LS RQ+ +V
Sbjct: 369 NIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAV 428
Query: 461 NVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEK-DQETSYTIIK 519
++TTNQAAPSPV +KK + ++NSISLSWQEP+ PNGIIL+YE+KY+EK +QETSYTI++
Sbjct: 429 SITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILR 488
Query: 520 SKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTP-VFAASSDQSQIPVIAVS 578
++ T +T LKP ++YVFQIRARTAAGYG SR+FEFET+P F+ S + SQ+ +IA+S
Sbjct: 489 ARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAIS 548
Query: 579 VTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFH 638
V +ILL VVI VL+ GR CGY K+K +E+++HF
Sbjct: 549 AAVAIILLTVVIYVLI---------GRF--------------CGY-KSKHGADEKRLHFG 584
Query: 639 NGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPG 698
NGH+KLPG+RTY+DPHTYEDP QAVHEFAKE++A+ I+I++V+GAGEFGEVCSGRLKLP
Sbjct: 585 NGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPS 644
Query: 699 KRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMEN 758
K+E+ VAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNII LEGVVTKSKPVMIVTEYMEN
Sbjct: 645 KKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMEN 704
Query: 759 GSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSD 818
GSLD+FL+K+D QFTVIQLVGMLRGI++GMKYLSDMGYVHRDLAARNILINSNLVCKVSD
Sbjct: 705 GSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSD 764
Query: 819 FGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERP 878
FGLSRVLEDDPEAAYTTRGGKIPIRWT+PEAIA+RKFTSASDVWSYGIV+WEV+SYGERP
Sbjct: 765 FGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERP 824
Query: 879 YWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRN 938
YWEM+NQDVIKAV+EGYRLP PMDCPAALYQLMLDCWQK+RN+RPKF++IV++LDKLIRN
Sbjct: 825 YWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRN 884
Query: 939 PSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVA 998
P SLK + +A+ R SNLL + S + +R+ G+WL + EIF YSS D +A
Sbjct: 885 PGSLKIITSAAARPSNLLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIA 944
Query: 999 QVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVPL 1037
+++ +D++++GVT+VG QKKI++S++ ++ Q NG VP+
Sbjct: 945 KISTDDMKKVGVTVVGPQKKIISSIKALETQSKNGPVPV 983
>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
Length = 998
Score = 1313 bits (3397), Expect = 0.0
Identities = 643/1012 (63%), Positives = 792/1012 (78%), Gaps = 43/1012 (4%)
Query: 37 RAPLWTCLLLCAALR---TLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENY 93
R P W L LR T A + EV LLDS+ +L WI+ P NGWEEI +DENY
Sbjct: 6 RYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENY 65
Query: 94 APIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNM 153
PI TYQVC+VME NQNNWL T+WIS A RIF+ELKFTLRDCNSLPG LGTCKETFN+
Sbjct: 66 TPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNL 125
Query: 154 YYFESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLA 213
YY+E+D GRNI+EN Y+KIDTIAADESFT+ DLG+R MKLNTEVR++GPLSKKGFYLA
Sbjct: 126 YYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLA 185
Query: 214 FQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSV--TDEP 271
FQDVGACIALVSV+VYYKKC S++ +LA+FPDT+TG++ S L+EV G+CV+ + +
Sbjct: 186 FQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENA 245
Query: 272 PKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEE 331
P+MHCSAEGEWLVPIGKC+CKAGY++K TC+ C GF+K+S C +CP HS++ +E
Sbjct: 246 PRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKE 305
Query: 332 ASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSY 391
S+ C CE Y+R SDPP +ACTRPPSAP+N I N+N+T+V LEW PPAD GGR DV+Y
Sbjct: 306 GSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTY 365
Query: 392 YIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLS 451
I CK+C+ G C CG ++ Y+P+Q+GL++ V ++DLLAH NYTFE+EAVNGVSDLS
Sbjct: 366 RILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLS 425
Query: 452 PGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQ 511
R + +V++TT QAAPS V+ V K ++ + S+ LSWQEP+ PNG+I EYEIKY+EKDQ
Sbjct: 426 RSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQ 485
Query: 512 -ETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTP--------V 562
E +Y+ +K+K T+ + LKP +VYVFQIRA TAAGYG +S R + T
Sbjct: 486 RERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEA 545
Query: 563 FAASSDQSQIPVIAVSVTVGVILLA-VVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRC 621
A SS+Q+ + +IAV G I+L +V G ++ GR C
Sbjct: 546 TAVSSEQNPVIIIAVVAVAGTIILVFMVFGFII---------GRR-------------HC 583
Query: 622 GYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVI 681
GYSKA Q+ +EE ++FH K PG +TYIDP TYEDPN+AVH+FAKE++ASCI IERVI
Sbjct: 584 GYSKADQEGDEE-LYFH---FKFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVI 639
Query: 682 GAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEG 741
GAGEFGEVCSGRLKLPGKR++ VAIKTLKVGYTEKQRRDFL EASIMGQFDHPN++HLEG
Sbjct: 640 GAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEG 699
Query: 742 VVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDL 801
VVT+ KPVMIV E+MENG+LD FL+K+DGQFTVIQLVGMLRGI+AGM+YL+DMGYVHRDL
Sbjct: 700 VVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDL 759
Query: 802 AARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDV 861
AARNIL+NSNLVCKVSDFGLSRV+EDDPEA YTT GGKIP+RWTAPEAI +RKFTSASDV
Sbjct: 760 AARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDV 819
Query: 862 WSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNS 921
WSYGIVMWEV+SYGERPYW+M+NQDVIKA+EEGYRLP+PMDCPA L+QLMLDCWQKER
Sbjct: 820 WSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAE 879
Query: 922 RPKFDEIVNMLDKLIRNPSSLKTLVNASCR-VSNLLAEHSPLGSGAYRSVGEWLEAIKMG 980
RPKF++IV +LDK+IRNP+SLKT + R +S LL +++P + SVGEWL+AIKM
Sbjct: 880 RPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQNTP-DFTTFCSVGEWLQAIKME 938
Query: 981 RYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVN 1032
RY + F GY+S+++VA++T+ED+ LG+TLVGHQKKIM+S+Q M+ Q+++
Sbjct: 939 RYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMSSIQTMRAQMLH 990
>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
Length = 986
Score = 1305 bits (3378), Expect = 0.0
Identities = 644/996 (64%), Positives = 771/996 (77%), Gaps = 33/996 (3%)
Query: 40 LWTCLL-LCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFP-KNGWEEIGEVDENYAPIH 97
L++CL +C A+ P+NEV LLDSR+V G+LGWIA P + GWEE+ +DE PI
Sbjct: 9 LFSCLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIR 68
Query: 98 TYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFE 157
TYQVC VME +QNNWL T WI+ EGA R++IE+KFTLRDCNSLPG +GTCKETFN+YY+E
Sbjct: 69 TYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYE 128
Query: 158 SDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDV 217
SD+ R I+ENQ++KIDTIAADESFT++D+GDR+MKLNTE+RDVGPLSKKGFYLAFQDV
Sbjct: 129 SDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDV 188
Query: 218 GACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCS 277
GACIALVSVRV+YKKCP VR+LA FPDTITGAD+S L+EV GSCVN+S + PKM+C
Sbjct: 189 GACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCG 248
Query: 278 AEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCV 337
A+GEWLVPIG C+C AG+EE++G CQ C+ G++KA +C KCPPHSY+ E +TSC
Sbjct: 249 ADGEWLVPIGNCLCNAGHEERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCT 308
Query: 338 CEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKK 397
C++ +FR ++D +M CTRPPSAP N ISNVNETSV LEW P +TGGR+D+SY + CKK
Sbjct: 309 CDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKK 368
Query: 398 CNS-HAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQ 456
C + C CG V Y P+Q+GLK T V + DLLAHTNYTFEI AVNGVS +P Q
Sbjct: 369 CGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQ 428
Query: 457 YVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQ-ETSY 515
VSV VTTNQAAPS + V+ ++ + S++L+W EPDRPNG+ILEYE+KY+EKDQ E SY
Sbjct: 429 SVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSY 488
Query: 516 TIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAAS-SDQSQIPV 574
I+++ +GL P + YVF +RARTAAGYG FS E T V + D + V
Sbjct: 489 RIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTV 548
Query: 575 IAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEK 634
+ VSV+ V+L+ ++I + R YSKAKQ+ +EEK
Sbjct: 549 LLVSVSGSVVLVVILIAAFVISRR---------------------RSKYSKAKQEADEEK 587
Query: 635 MHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRL 694
H+ GVRTY+DP TYEDPNQAV EFAKEI+ASCI IE+VIG GEFGEVCSGRL
Sbjct: 588 ------HLN-QGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRL 640
Query: 695 KLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTE 754
K+PGKRE+ VAIKTLK GYT+KQRRDFL EASIMGQFDHPNIIHLEGVVTK KPVMI+TE
Sbjct: 641 KVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITE 700
Query: 755 YMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVC 814
YMENGSLD FL+KNDG+FTVIQLVGMLRGI +GMKYLSDM YVHRDLAARNIL+NSNLVC
Sbjct: 701 YMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVC 760
Query: 815 KVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSY 874
KVSDFG+SRVLEDDPEAAYTTRGGKIPIRWTAPEAIA+RKFTSASDVWSYGIVMWEV+SY
Sbjct: 761 KVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSY 820
Query: 875 GERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDK 934
GERPYW+M+NQDVIKA+EEGYRLP PMDCP AL+QLMLDCWQKER+ RPKF +IVNMLDK
Sbjct: 821 GERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDK 880
Query: 935 LIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSM 994
LIRNP+SLK S R + L + S A SVG+WL+AIKM RY + F GY+++
Sbjct: 881 LIRNPNSLKRTGTESSRPNTALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTL 940
Query: 995 DAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQL 1030
+AV V EDL R+G+T + HQ KI++S+Q M+ Q+
Sbjct: 941 EAVVHVNQEDLARIGITAITHQNKILSSVQAMRTQM 976
>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
Length = 1130
Score = 1243 bits (3217), Expect = 0.0
Identities = 606/1024 (59%), Positives = 767/1024 (74%), Gaps = 76/1024 (7%)
Query: 58 SNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSW 117
+N+V LLD+ TV+G+LGW +P NGW+ I E+DE+ PIHTYQVC VME NQNNWL T+W
Sbjct: 126 NNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNWLRTNW 185
Query: 118 ISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTI 177
IS + A +I++E+KFTLRDCNS+P LGTCKETFN++Y ESD+ +G K NQY KIDTI
Sbjct: 186 ISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYTKIDTI 245
Query: 178 AADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVV 237
AADESFT++DLGDR++KLNTE+R+VGP+ +KGFYLAFQD+GACIALVSVRV+YKKCP V
Sbjct: 246 AADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTV 305
Query: 238 RHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEE 297
R+LA+FPDTI DSS L+EV GSCV + + PK++C A+G+WLVP+G+C+C GYEE
Sbjct: 306 RNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICSTGYEE 365
Query: 298 KNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRP 357
G+C CRPGF+KA C KCPPHS T+ EA++ C CEK YFR E DPP+MACTRP
Sbjct: 366 IEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSMACTRP 425
Query: 358 PSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPR 417
PSAPRN + N+NET++ LEW PP+DTGGRKD++Y + CKKC CE+CGG +R++PR
Sbjct: 426 PSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFIPR 485
Query: 418 QSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKK 477
+GL N SV+++D ++H NYTFEIEA+NGVS+LS + + ++ VTT+Q APS + V+K
Sbjct: 486 HTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLIGVVRK 545
Query: 478 GKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQE-TSYTIIKSKETTITAEGLKPASVY 536
++NSI+LSWQ P NG IL+YEIKY+EK+ E +Y+ +SK ++ GLKPA+ Y
Sbjct: 546 DWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATKY 605
Query: 537 VFQIRARTAAGYGVFSRRFEFET-TPVFAASSDQSQIPVIAVSVTVGVILLAVV-IGVLL 594
VF IR RTA GY +S++FEFET +++Q QI VIA + G LL ++ + L+
Sbjct: 606 VFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLI 665
Query: 595 SGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKM-HFHNGHIKLPGVRTYIDP 653
+G C W Y KAK EE++ H NGH++ PG++TYIDP
Sbjct: 666 TGRC-------------------QW---YIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDP 703
Query: 654 HTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGY 713
TYEDP+ AVHEFAKEI+ S I IERVIGAGEFGEVCSGRLK PGKRE+PVAIKTLK G+
Sbjct: 704 DTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGH 763
Query: 714 TEKQRRDFLGEASIMGQFDHPNIIHLEGVVTK---------------------------- 745
++QRRDFL EASIMGQFDHPNII LEGVVTK
Sbjct: 764 MDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPH 823
Query: 746 --------------SKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYL 791
+PVMIV EYMENGSLD+FL+K+DG FTVIQLVGMLRGI++GMKYL
Sbjct: 824 PVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYL 883
Query: 792 SDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA 851
SDMGYVHRDLAARNIL+NSNLVCKVSDFGLSRVLEDDPEAAYTT GGKIPIRWTAPEAIA
Sbjct: 884 SDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIA 943
Query: 852 FRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLM 911
+RKF+SASD WSYGIVMWEV+SYGERPYWEM+NQDVI ++EEGYRLP+PM CPA+L+QLM
Sbjct: 944 YRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLM 1003
Query: 912 LDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYR--- 968
L CWQKERN RPKF +IV+ LDKLIRNPS+L TLV L+ SP Y
Sbjct: 1004 LHCWQKERNHRPKFTDIVSFLDKLIRNPSALHTLVE-----DILVMPESPGEVPEYPLFV 1058
Query: 969 SVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKV 1028
+VG+WL++IKMG+Y F+ G+++ D +++++++D+RR+GV L+GHQ++I++S+Q +++
Sbjct: 1059 TVGDWLDSIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRL 1118
Query: 1029 QLVN 1032
+++
Sbjct: 1119 HMMH 1122
>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapiens]
Length = 1005
Score = 1212 bits (3137), Expect = 0.0
Identities = 587/1016 (57%), Positives = 747/1016 (73%), Gaps = 45/1016 (4%)
Query: 40 LWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTY 99
LW + AA T +++ EVNLLD+ T+ GD GW+ +P +GW+ I EVDE++ PIHTY
Sbjct: 12 LWV-VTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTY 70
Query: 100 QVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESD 159
QVC VM NQNNWL TSW+ +GA R++ E+KFTLRDCNS+PG LGTCKETFN+YY ESD
Sbjct: 71 QVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESD 130
Query: 160 DQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGA 219
G + +E+Q++KIDTIAADESFT DLG R +KLNTEVR VGPLSK+GFYLAFQD+GA
Sbjct: 131 RDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGA 190
Query: 220 CIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAE 279
C+A++S+R+YYKKCP++VR+LA F + +TGADSS L+EV G CV HS + PKM+CSAE
Sbjct: 191 CLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAE 250
Query: 280 GEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCE 339
GEWLVPIGKC+C AGYEE+ C C GF+K++P Q C +CPPHS++ A+ +C C+
Sbjct: 251 GEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCD 310
Query: 340 KDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCN 399
Y+R DPP+ ACTRPPSAP N IS+VN TSV LEW PP D GGR D++Y C++C
Sbjct: 311 LSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCP 370
Query: 400 SHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVS 459
CE CG R++P+Q+ L S+++ +LLAH NY+F IEAVNGVSDLSP R+
Sbjct: 371 WALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAV 430
Query: 460 VNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQE-TSYTII 518
VN+TTNQAAPS V +++ + + S+SL WQEP++PNGIILEYEIKY+EKD+E SY+ +
Sbjct: 431 VNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTL 490
Query: 519 KSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVS 578
K+ T T GLKP + YVFQ+RART+AG G FS+ E ET D I I ++
Sbjct: 491 KAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKP-RPRYDTRTIVWICLT 549
Query: 579 VTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFH 638
+ G+++L +++ +C H CGYSKA QD +EEKMH+
Sbjct: 550 LITGLVVLLLLL------------------ICKKRH------CGYSKAFQDSDEEKMHYQ 585
Query: 639 NGHI-------------KLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGE 685
NG KLP + Y +PHTYE+P +A F +EIEAS I IE++IG+G+
Sbjct: 586 NGQAPPPVFLPLHHPPGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGD 645
Query: 686 FGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTK 745
GEVC GRL++PG+R++PVAIK LK GYTE+QRRDFL EASIMGQFDHPNII LEGVVT+
Sbjct: 646 SGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTR 705
Query: 746 SKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARN 805
+ MIVTEYMENGSLDTFL+ +DGQFT++QLVGMLRG+ AGM+YLSD+GYVHRDLAARN
Sbjct: 706 GRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARN 765
Query: 806 ILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYG 865
+L++SNLVCKVSDFGLSRVLEDDP+AAYTT GGKIPIRWTAPEAIAFR F+SASDVWS+G
Sbjct: 766 VLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFG 825
Query: 866 IVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKF 925
+VMWEV++YGERPYW MTN+DVI +VEEGYRLP+PM CP AL+QLMLDCW K+R RP+F
Sbjct: 826 VVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRF 885
Query: 926 DEIVNMLDKLIRNPSSLKTLVNAS-----CRVSNLLAEHSPLGSGAYRSVGEWLEAIKMG 980
+IV++LD LIR+P SL+ S V + G G +VG+WL++I+MG
Sbjct: 886 SQIVSVLDALIRSPESLRATATVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMG 945
Query: 981 RYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVP 1036
RY + F GYSS+ V ++ +D+R LG+TL+GHQKKI+ S+Q M+ QL + P
Sbjct: 946 RYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGP 1001
>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapiens]
Length = 987
Score = 1165 bits (3014), Expect = 0.0
Identities = 575/996 (57%), Positives = 740/996 (74%), Gaps = 33/996 (3%)
Query: 46 LCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVM 105
L AAL L + E L+DS T +LGW+ P +GWEE+ DEN I TYQVC V
Sbjct: 6 LGAALLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVF 65
Query: 106 EQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGR- 164
E +QNNWL T +I GA RI +E+KF++RDC+S+P G+CKETFN+YY+E+D +
Sbjct: 66 ESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATK 125
Query: 165 ---NIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACI 221
N EN ++K+DTIAADESF+++DLG RVMK+NTEVR GP+S+ GFYLAFQD G C+
Sbjct: 126 TFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCM 185
Query: 222 ALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCV-NHSVTDEPPKMHCSAEG 280
+L++VRV+Y+KCP ++++ A+F +T++GA+S+ L+ GSC+ N D P K++C+ +G
Sbjct: 186 SLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDG 245
Query: 281 EWLVPIGKCMCKAGYEE-KNGT-CQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVC 338
EWLVPIG+CMCKAG+E +NGT C+ C G FKA+ ++C CP +S T E +T+CVC
Sbjct: 246 EWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVC 305
Query: 339 EKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKC 398
Y+R + DP M CT PSAP+ IS+VNETS+ LEW PP D+GGR+D+ Y I CK C
Sbjct: 306 RNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSC 365
Query: 399 NSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYV 458
S G C CG +V+Y PRQ GL + + DLLAHT YTFEI+AVNGV+D SP + Q+
Sbjct: 366 GSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFA 425
Query: 459 SVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKD-QETSYTI 517
SVN+TTNQAAPS V+ + + +SI+LSW +PD+PNG+IL+YE++Y+EK+ E + T
Sbjct: 426 SVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATA 485
Query: 518 IKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFET-TPVFAASSDQSQIPVIA 576
IKS T+T +GLK ++YVFQ+RART AGYG +S + F+T T +S Q ++P+I
Sbjct: 486 IKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLII 545
Query: 577 VSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMH 636
S G++ L V+ + + C R R G+ +A + ++ H
Sbjct: 546 GSSAAGLVFLIAVVVIAIV-------CNR--------------RRGFERADSEYTDKLQH 584
Query: 637 FHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKL 696
+ +GH+ PG++ YIDP TYEDPN+AV EFAKEI+ SC+ IE+VIGAGEFGEVCSG LKL
Sbjct: 585 YTSGHMT-PGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKL 643
Query: 697 PGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYM 756
PGKRE+ VAIKTLK GYTEKQRRDFL EASIMGQFDHPN+IHLEGVVTKS PVMI+TE+M
Sbjct: 644 PGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFM 703
Query: 757 ENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKV 816
ENGSLD+FL++NDGQFTVIQLVGMLRGI+AGMKYL+DM YVHRDLAARNIL+NSNLVCKV
Sbjct: 704 ENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKV 763
Query: 817 SDFGLSRVLEDD-PEAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSY 874
SDFGLSR LEDD + YT+ GGKIPIRWTAPEAI +RKFTSASDVWSYGIVMWEV+SY
Sbjct: 764 SDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSY 823
Query: 875 GERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDK 934
GERPYW+MTNQDVI A+E+ YRLP PMDCP+AL+QLMLDCWQK+RN RPKF +IVN LDK
Sbjct: 824 GERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDK 883
Query: 935 LIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSM 994
+IRNP+SLK + S ++ L + + ++ +V EWLEAIKMG+Y E F G++S
Sbjct: 884 MIRNPNSLKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSF 943
Query: 995 DAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQL 1030
D V+Q+ +ED+ R+GVTL GHQKKI+NS+Q M+ Q+
Sbjct: 944 DVVSQMMMEDILRVGVTLAGHQKKILNSIQVMRAQM 979
>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sapiens]
Length = 986
Score = 1164 bits (3010), Expect = 0.0
Identities = 574/996 (57%), Positives = 739/996 (74%), Gaps = 34/996 (3%)
Query: 46 LCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVM 105
L AAL L + E L+DS T +LGW+ P +GWEE+ DEN I TYQVC V
Sbjct: 6 LGAALLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVF 65
Query: 106 EQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGR- 164
E +QNNWL T +I GA RI +E+KF++RDC+S+P G+CKETFN+YY+E+D +
Sbjct: 66 ESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATK 125
Query: 165 ---NIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACI 221
N EN ++K+DTIAADESF+++DLG RVMK+NTEVR GP+S+ GFYLAFQD G C+
Sbjct: 126 TFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCM 185
Query: 222 ALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCV-NHSVTDEPPKMHCSAEG 280
+L++VRV+Y+KCP ++++ A+F +T++GA+S+ L+ GSC+ N D P K++C+ +G
Sbjct: 186 SLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDG 245
Query: 281 EWLVPIGKCMCKAGYEE-KNGT-CQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVC 338
EWLVPIG+CMCKAG+E +NGT C+ C G FKA+ ++C CP +S T E +T+CVC
Sbjct: 246 EWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVC 305
Query: 339 EKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKC 398
Y+R + DP M CT PSAP+ IS+VNETS+ LEW PP D+GGR+D+ Y I CK C
Sbjct: 306 RNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSC 365
Query: 399 NSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYV 458
S G C CG +V+Y PRQ GL + + DLLAHT YTFEI+AVNGV+D SP + Q+
Sbjct: 366 GSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFA 425
Query: 459 SVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKD-QETSYTI 517
SVN+TTNQAAPS V+ + + +SI+LSW +PD+PNG+IL+YE++Y+EK+ E + T
Sbjct: 426 SVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATA 485
Query: 518 IKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFET-TPVFAASSDQSQIPVIA 576
IKS T+T +GLK ++YVFQ+RART AGYG +S + F+T T +S Q ++P+I
Sbjct: 486 IKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLII 545
Query: 577 VSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMH 636
S G++ L V+ + + C R G+ +A + ++ H
Sbjct: 546 GSSAAGLVFLIAVVVIAIV-------CNRR---------------GFERADSEYTDKLQH 583
Query: 637 FHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKL 696
+ +GH+ PG++ YIDP TYEDPN+AV EFAKEI+ SC+ IE+VIGAGEFGEVCSG LKL
Sbjct: 584 YTSGHMT-PGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKL 642
Query: 697 PGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYM 756
PGKRE+ VAIKTLK GYTEKQRRDFL EASIMGQFDHPN+IHLEGVVTKS PVMI+TE+M
Sbjct: 643 PGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFM 702
Query: 757 ENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKV 816
ENGSLD+FL++NDGQFTVIQLVGMLRGI+AGMKYL+DM YVHRDLAARNIL+NSNLVCKV
Sbjct: 703 ENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKV 762
Query: 817 SDFGLSRVLEDD-PEAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSY 874
SDFGLSR LEDD + YT+ GGKIPIRWTAPEAI +RKFTSASDVWSYGIVMWEV+SY
Sbjct: 763 SDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSY 822
Query: 875 GERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDK 934
GERPYW+MTNQDVI A+E+ YRLP PMDCP+AL+QLMLDCWQK+RN RPKF +IVN LDK
Sbjct: 823 GERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDK 882
Query: 935 LIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSM 994
+IRNP+SLK + S ++ L + + ++ +V EWLEAIKMG+Y E F G++S
Sbjct: 883 MIRNPNSLKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSF 942
Query: 995 DAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQL 1030
D V+Q+ +ED+ R+GVTL GHQKKI+NS+Q M+ Q+
Sbjct: 943 DVVSQMMMEDILRVGVTLAGHQKKILNSIQVMRAQM 978
>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
Length = 984
Score = 1130 bits (2924), Expect = 0.0
Identities = 570/993 (57%), Positives = 723/993 (72%), Gaps = 35/993 (3%)
Query: 50 LRTLLASP--SNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQ 107
L LLAS + E L+D+RT +LGW A P +GWEE+ DEN I TYQVC V E
Sbjct: 7 LLLLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEP 66
Query: 108 NQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDD----QNG 163
NQNNWLLT++I+ GA RI+ E++FT+RDC+SLP G+CKETFN+YY+E+D +
Sbjct: 67 NQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKS 126
Query: 164 RNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIAL 223
E Y+K+DTIAADESF+++D G R+MK+NTEVR GPL++ GFYLAFQD GAC++L
Sbjct: 127 AFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSL 186
Query: 224 VSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCV-NHSVTDEPPKMHCSAEGEW 282
+SVRV++KKCPS+V++ AVFP+T+TGA+S+ L+ G+C+ N D P K++C+ +GEW
Sbjct: 187 LSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEW 246
Query: 283 LVPIGKCMCKAGYEEKNGT-CQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKD 341
+VPIG+C CK GYE +N C+ C G FKAS + C CP +S + EAS C C
Sbjct: 247 MVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTG 306
Query: 342 YFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSH 401
Y+R + DPP +ACT PS PRN IS VNETS+ LEW PP +TGGR DV+Y I CKKC +
Sbjct: 307 YYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRAD 366
Query: 402 AGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVN 461
C C +V ++PRQ GL V + L AHT YTF+I+A+NGVS SP Q+VSVN
Sbjct: 367 RRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVN 426
Query: 462 VTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQ-ETSYTIIKS 520
+TTNQAAPS V + + SI+LSW +P++PNGIIL+YEI+Y+EK+ E + ++ +S
Sbjct: 427 ITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARS 486
Query: 521 KETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFET-TPVFAASSDQSQIPVIAVSV 579
+ T +GL+P VYV Q+RART AGYG FS + F+T T S + Q+P+IA S
Sbjct: 487 QTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSA 546
Query: 580 TVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHN 639
GV+ + ++ + + C RA S AV YS Q H+
Sbjct: 547 AAGVVFVVSLVAISIV-----CSRKRAYSKEAV----------YSDKLQ-------HYST 584
Query: 640 GHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGK 699
G PG++ YIDP TYEDPN+AV EFAKEI+ S + IE VIGAGEFGEV GRLKLPGK
Sbjct: 585 GRGS-PGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGK 643
Query: 700 RELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENG 759
RE+ VAIKTLK GY+EKQRRDFL EASIMGQFDHPNII LEGVVTKS+PVMI+TE+MENG
Sbjct: 644 REIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENG 703
Query: 760 SLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDF 819
+LD+FL++NDGQFTVIQLVGMLRGI+AGMKYL++M YVHRDLAARNIL+NSNLVCKVSDF
Sbjct: 704 ALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDF 763
Query: 820 GLSRVLEDD-PEAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGER 877
GLSR L+DD + YT+ GGKIP+RWTAPEAIA+RKFTSASDVWSYGIVMWEV+S+GER
Sbjct: 764 GLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGER 823
Query: 878 PYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIR 937
PYW+M+NQDVI A+E+ YRLP PMDCPAAL+QLMLDCWQK+RNSRP+F EIVN LDK+IR
Sbjct: 824 PYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIR 883
Query: 938 NPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAV 997
NP+SLKT+ + S L + S A+ +V +WL AIKM +Y + F+ G++S+ V
Sbjct: 884 NPASLKTVATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLV 943
Query: 998 AQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQL 1030
Q+T EDL R+G+TL GHQKKI+NS+ M+VQ+
Sbjct: 944 TQMTSEDLLRIGITLAGHQKKILNSIHSMRVQI 976
>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
Length = 998
Score = 1088 bits (2813), Expect = 0.0
Identities = 551/1009 (54%), Positives = 705/1009 (69%), Gaps = 45/1009 (4%)
Query: 35 PRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYA 94
P PL LLL L + E L+D++ V +L W + P++GWEE+ DE
Sbjct: 14 PGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMN 73
Query: 95 PIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMY 154
PI TYQVC V E +QNNWL T +I R+++ELKFT+RDCNS+P G+CKETFN++
Sbjct: 74 PIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLF 133
Query: 155 YFESDDQNGRNIK----ENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGF 210
Y+E+D EN Y+K+DTIA DESF+ LD G ++NT+VR GPLSK GF
Sbjct: 134 YYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGF 189
Query: 211 YLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSV-TD 269
YLAFQD GAC++L+SVR +YKKC S A+FP+T+TGA+ + L+ G+C+ ++V
Sbjct: 190 YLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVS 249
Query: 270 EPPKMHCSAEGEWLVPIGKCMCKAGYEE--KNGTCQVCRPGFFKASPHIQSCGKCPPHSY 327
P K++C+ +GEW+VP+G C C G+E K C+ C PG +KA C CPP+S
Sbjct: 250 VPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSR 309
Query: 328 THEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRK 387
T A++ C C +++R +SD ACT PS PR ISNVNETS+ LEW P D GGR
Sbjct: 310 TTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRD 369
Query: 388 DVSYYIACKKCNSHAGV--CEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVN 445
D+ Y + CKKC+ G C C +V ++PRQ GL V + LLAHT YTFE++AVN
Sbjct: 370 DLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVN 429
Query: 446 GVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIK 505
GVS SP +Y +VN+TTNQAAPS V ++ + +S++LSW P+RPNG+IL+YE+K
Sbjct: 430 GVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMK 489
Query: 506 YFEKDQETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAA 565
YFEK + + T+ S+ ++ +GL+P + YV Q+RART AGYG +SR EFETT +
Sbjct: 490 YFEKSEGIASTVT-SQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGS 548
Query: 566 SSDQ--SQIPVIAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGY 623
+ Q Q+P+I S T G++ + V+ + + C R
Sbjct: 549 GAQQLQEQLPLIVGSATAGLVFVVAVVVIAIV-------CLR------------------ 583
Query: 624 SKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGA 683
K + + E +I PG++ YIDP TYEDPN+AV EFAKEI+ SC+ IE VIGA
Sbjct: 584 -KQRHGSDSEYTEKLQQYIA-PGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGA 641
Query: 684 GEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVV 743
GEFGEVC GRLK PG+RE+ VAIKTLKVGYTE+QRRDFL EASIMGQFDHPNII LEGVV
Sbjct: 642 GEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVV 701
Query: 744 TKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAA 803
TKS+PVMI+TE+MEN +LD+FL+ NDGQFTVIQLVGMLRGI+AGMKYLS+M YVHRDLAA
Sbjct: 702 TKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAA 761
Query: 804 RNILINSNLVCKVSDFGLSRVLEDDP-EAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDV 861
RNIL+NSNLVCKVSDFGLSR LEDDP + YT+ GGKIPIRWTAPEAIA+RKFTSASDV
Sbjct: 762 RNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDV 821
Query: 862 WSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNS 921
WSYGIVMWEV+SYGERPYW+M+NQDVI AVE+ YRLP PMDCP AL+QLMLDCW ++RN
Sbjct: 822 WSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNL 881
Query: 922 RPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGR 981
RPKF +IVN LDKLIRN +SLK + +A +S L + + + +VG+WL+AIKMGR
Sbjct: 882 RPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGR 941
Query: 982 YTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQL 1030
Y E F+ G++S D VAQ+T EDL R+GVTL GHQKKI++S+Q+M++Q+
Sbjct: 942 YKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQM 990
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 1015 bits (2625), Expect = 0.0
Identities = 524/1005 (52%), Positives = 680/1005 (67%), Gaps = 44/1005 (4%)
Query: 38 APLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKN-GWEEIGEVDENYAPI 96
A LW C L AA A+ EV LLD G+LGW+ P GW+ + + N PI
Sbjct: 11 ALLWGCALAAAA-----AAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNI-MNDMPI 64
Query: 97 HTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYF 156
+ Y VC VM +Q+NWL T+W+ A RIFIELKFT+RDCNS PGG +CKETFN+YY
Sbjct: 65 YMYSVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYA 124
Query: 157 ESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQD 216
ESD G N ++ + KIDTIA DE D R +KLN E R VGPL++KGFYLAFQD
Sbjct: 125 ESDLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQD 184
Query: 217 VGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTD---EPPK 273
+GAC+AL+SVRVYYKKCP +++ LA FP+TI G+D+ L V+G+CV+H+V E P+
Sbjct: 185 IGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPR 244
Query: 274 MHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEAS 333
MHC+ +GEWLVPIG+C+C+AGYE+ CQ C PGFFK C +CP H+ E +
Sbjct: 245 MHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGA 304
Query: 334 TSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYI 393
TSC CE+ +FR DP +M CTRPPSAP + V L W PP D+GGR+D+ Y +
Sbjct: 305 TSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSV 364
Query: 394 ACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPG 453
C++C +G C C VRY GL TSV + DL H NYTF +EA NGVS L
Sbjct: 365 TCEQCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVT- 423
Query: 454 ARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQET 513
+R + + +V+ NQ P V +G+ + S+S+SW P + +YE+ Y +K
Sbjct: 424 SRSFRTASVSINQTEPPKVR--LEGR-STTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSN 480
Query: 514 SYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIP 573
SY + +++ ++T + L P + Y+ Q++A T G G S+ EF+T S + S
Sbjct: 481 SYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTL-----SPEGSGNL 535
Query: 574 VIAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEE 633
+ V VGV+LL V+ GV + R +A+Q PE+
Sbjct: 536 AVIGGVAVGVVLLLVLAGVGFF---------------------IHRRRKNQRARQSPED- 573
Query: 634 KMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGR 693
++F +L ++TY+DPHTYEDPNQAV +F EI SC+T ++VIGAGEFGEV G
Sbjct: 574 -VYFSKSE-QLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGM 631
Query: 694 LKLP-GKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIV 752
LK GK+E+PVAIKTLK GYTEKQR DFLGEA IMGQF H NII LEGV++K KP+MI+
Sbjct: 632 LKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMII 691
Query: 753 TEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNL 812
TEYMENG+LD FL++ DG+F+V+QLVGMLRGI+AGMKYL++M YVHRDLAARNIL+NSNL
Sbjct: 692 TEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNL 751
Query: 813 VCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVV 872
VCKVSDFGLSRVLEDDPEA YTT GGKIPIRWTAPEAI++RKFTSASDVWS+GIVMWEV+
Sbjct: 752 VCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVM 811
Query: 873 SYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNML 932
+YGERPYWE++N +V+KA+ +G+RLP+PMDCP+A+YQLM+ CWQ+ER RPKF +IV++L
Sbjct: 812 TYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSIL 871
Query: 933 DKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYS 992
DKLIR P SLKTL + RVS L S +R+V EWLE+IKM +YTE FM GY+
Sbjct: 872 DKLIRAPDSLKTLADFDPRVSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYT 931
Query: 993 SMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVPL 1037
+++ V Q+T +D++R+GV L GHQK+I SL +K Q+ +P+
Sbjct: 932 AIEKVVQMTNDDIKRIGVRLPGHQKRIAYSLLGLKDQVNTVGIPI 976
>gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
Length = 1008
Score = 926 bits (2394), Expect = 0.0
Identities = 481/1022 (47%), Positives = 668/1022 (65%), Gaps = 50/1022 (4%)
Query: 33 SAPRRAPLWTCLL-LCAALRTLLASP--SNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEV 89
+ P L+ C + LC AL P + EV LLDS+ +LGW A P NGWEEI V
Sbjct: 5 AGPHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGV 64
Query: 90 DENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKE 149
DE+ PI TYQVC V+E NQ+NWL T WIS RIF+EL+FTLRDC+S+PG GTCKE
Sbjct: 65 DEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKE 124
Query: 150 TFNMYYFESDDQNGRN---IKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLS 206
TFN+YY E++ GR + ++ KIDTIAADESFT+ DLG+R MKLNTEVR++GPLS
Sbjct: 125 TFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLS 184
Query: 207 KKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHS 266
++GF+LAFQDVGAC+ALVSVRVYYK+C + VR LA FP T + S L+EV+G+CV HS
Sbjct: 185 RRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHS 244
Query: 267 VTD--EPPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPP 324
+ PP+MHC A+GEWLVP+G+C C AG++E+ C+ C PGF+K SP C CP
Sbjct: 245 EGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCSPCPE 304
Query: 325 HSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLE--WIPPAD 382
HS E AST CVC+ Y R +DPP+ +CTRPPSAPR+ +++ + + L W+PPAD
Sbjct: 305 HSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPAD 364
Query: 383 TGGRKDVSYYIACKKCNSH--AGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFE 440
+GGR DV+Y + C +C AG CE CG V +LPRQ+GL+ + ++ L YT
Sbjct: 365 SGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVR 424
Query: 441 IEAVNGVSDLSPGA-RQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEP---DRPN 496
+ A+NGVS + A Y V V+T AP +++ ++ S+SLSW+EP P
Sbjct: 425 VAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPG 484
Query: 497 GIILEYEIKYFEKDQ-ETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGV---FS 552
EYEI+Y+EK Q E +Y+++K+ T+T LKPA+ YVFQIRA + F+
Sbjct: 485 ANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSFN 544
Query: 553 RRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAV 612
E +T AAS + Q P A+ VTV I +V+G ++S
Sbjct: 545 PSIEVQTLGE-AASGSRDQSP--AIVVTVVTISALLVLGSVMSVLA-------------- 587
Query: 613 AHPSLIWR--CGYSKAKQDP-EEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKE 669
IWR C Y K D +EE+++FH K+P RT++DP + D QAVH FAKE
Sbjct: 588 -----IWRRPCSYGKGGGDAHDEEELYFH---FKVPTRRTFLDPQSCGDLLQAVHLFAKE 639
Query: 670 IEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMG 729
++A +T+ER +G G FGE+C G L+LPG++EL VA+ L+ ++ QR FL EA +G
Sbjct: 640 LDAKSVTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLG 699
Query: 730 QFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMK 789
QFDH +I+ LEGVVT+ +MIVTEYM +G+LD FL++++GQ QL+G+L G+++ MK
Sbjct: 700 QFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMK 759
Query: 790 YLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEA 849
YLS+MGYVHR LAAR++L++S+LVCK+S FG R D EA YTT G+ P W APE
Sbjct: 760 YLSEMGYVHRGLAARHVLVSSDLVCKISGFG--RGPRDRSEAVYTTMSGRSPALWAAPET 817
Query: 850 IAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQ 909
+ F F+SASDVWS+GI+MWEV+++GERPYW+M+ QDVIKAVE+G+RLP P +CP L++
Sbjct: 818 LQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHR 877
Query: 910 LMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRS 969
LMLDCWQK+ RP+F +I ++L K++++P K + R LA+ + ++ S
Sbjct: 878 LMLDCWQKDPGERPRFSQIHSILSKMVQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGS 937
Query: 970 VGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQ 1029
VG WLEA+ + RY + F GY S++AVA++T +DL LG++L H++ +++ + ++ +
Sbjct: 938 VGAWLEALDLCRYKDSFAAAGYGSLEAVAEMTAQDLVSLGISLAEHREALLSGISALQAR 997
Query: 1030 LV 1031
++
Sbjct: 998 VL 999
>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
Length = 987
Score = 917 bits (2371), Expect = 0.0
Identities = 487/1007 (48%), Positives = 651/1007 (64%), Gaps = 53/1007 (5%)
Query: 44 LLLC-AALRTLLASPSNEVNLLDSRTVMGDLGWIAFPK--NGWEEIGEVDENYAPIHTYQ 100
+LLC A+L L E LL+++ DL W+ FP+ WEE+ +DE + TY+
Sbjct: 5 VLLCWASLAAAL-----EETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYE 59
Query: 101 VCKVMEQ-NQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESD 159
VC V Q +WL T W+ GA ++ L+FT+ +C SLP +CKETF ++Y+ESD
Sbjct: 60 VCDVQRAPGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESD 119
Query: 160 DQNGRNIK----ENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQ 215
+ EN YIK+DT+AA+ + + K+N + +GPLSK GFYLAFQ
Sbjct: 120 ADTATALTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQ 179
Query: 216 DVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVT--DEPPK 273
D GAC+AL+S+ ++YKKC + +L FP+T+ ++ V+GSCV +V P
Sbjct: 180 DQGACMALLSLHLFYKKCAQLTVNLTRFPETVP---RELVVPVAGSCVVDAVPAPGPSPS 236
Query: 274 MHCSAEGEWLV-PIGKCMCKAGYE--EKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHE 330
++C +G+W P+ C C G+E E N C+ C G FK SC CP +S+++
Sbjct: 237 LYCREDGQWAEQPVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNT 296
Query: 331 EASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVS 390
S C C YFR +DP CT PPSAPR+ +S +N +S+ LEW P ++GGR+D++
Sbjct: 297 IGSAVCQCRVGYFRARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLT 356
Query: 391 YYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL 450
Y + C++C G C CGG + + P L V++ L YTFE+ A+NGVS L
Sbjct: 357 YALRCRECRP-GGSCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSL 415
Query: 451 SPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKD 510
+ G + VNVTT++ P V++++ + + +S+SL+W P P+G +L+YE+KY EK
Sbjct: 416 ATGPVPFEPVNVTTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKG 475
Query: 511 QE--TSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSD 568
E +S +K+ E GLK + Y+ Q+RAR+ AGYG F + +T + +
Sbjct: 476 AEGPSSVRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQ-LDESEGW 534
Query: 569 QSQIPVIAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQ 628
+ Q+ +IA + VGV+L+ VVI V + LC K
Sbjct: 535 REQLALIAGTAVVGVVLVLVVIVVAV--------------LCL------------RKQSN 568
Query: 629 DPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGE 688
E E H ++ G + YIDP TYEDPN+AV EFAKEI+ S + IE VIGAGEFGE
Sbjct: 569 GREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGE 628
Query: 689 VCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKP 748
VC GRLK PGK+E VAIKTLK GYTE+QRR+FL EASIMGQF+HPNII LEGVVT S P
Sbjct: 629 VCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMP 688
Query: 749 VMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILI 808
VMI+TE+MENG+LD+FL+ NDGQFTVIQLVGMLRGI++GM+YL++M YVHRDLAARNIL+
Sbjct: 689 VMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILV 748
Query: 809 NSNLVCKVSDFGLSRVLEDD-PEAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGI 866
NSNLVCKVSDFGLSR LE++ + YT+ GGKIPIRWTAPEAIAFRKFTSASD WSYGI
Sbjct: 749 NSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGI 808
Query: 867 VMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFD 926
VMWEV+S+GERPYW+M+NQDVI A+E+ YRLP P DCP +L+QLMLDCWQK+RN+RP+F
Sbjct: 809 VMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFP 868
Query: 927 EIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIF 986
++V+ LDK+IRNP+SLK + + S+ L + A+ SVGEWL AIKMGRY E F
Sbjct: 869 QVVSALDKMIRNPASLKIVARENGGASHPLLDQRQPHYSAFGSVGEWLRAIKMGRYEESF 928
Query: 987 MENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNG 1033
G+ S + V+Q++ EDL R+GVTL GHQKKI+ S+Q MK Q G
Sbjct: 929 AAAGFGSFELVSQISAEDLLRIGVTLAGHQKKILASVQHMKSQAKPG 975
>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
Length = 976
Score = 789 bits (2037), Expect = 0.0
Identities = 435/1009 (43%), Positives = 612/1009 (60%), Gaps = 53/1009 (5%)
Query: 36 RRAPLWT--CLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFP-KNGWEEIGEVDEN 92
RR PL LLLCA L + + EV L+D+ G+LGW+ P K+GW E ++ N
Sbjct: 3 RRWPLGLGLVLLLCAPLPP--GARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LN 59
Query: 93 YAPIHTYQVCKVM-EQNQNNWLLTSWI-SNEGASRIFIELKFTLRDCNSLPGGLGT--CK 148
P++ YQ C + ++ ++WL ++WI E ASR+ +EL+FT+RDC S PGG G CK
Sbjct: 60 GTPLYMYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCK 119
Query: 149 ETFNMYYFESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKK 208
ETFN+ Y ESD G ++ + K+ T+AAD+SFT DL +KLN E +G L+++
Sbjct: 120 ETFNLLYMESDQDVGIQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRR 179
Query: 209 GFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHS-V 267
G YLAF + GAC+ALVSVRV+Y++CP + LA FPDT+ G + L+EV+G+C+ H+
Sbjct: 180 GLYLAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGP--AGLVEVAGTCLPHARA 237
Query: 268 TDEP---PKMHCSAEGEWLVPIGKCMCKAGYEEKNG--TCQVCRPGFFKASPHIQSCGKC 322
+ P P+MHCS +GEWLVP+G+C C+ GYEE C C G ++ C C
Sbjct: 238 SPRPSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTC 297
Query: 323 PPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPAD 382
P S E +T C CE ++R + P +ACT PPSAPRN + + T + L W PPAD
Sbjct: 298 PQQSTAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPAD 357
Query: 383 TGGRKDVSYYIACKKCNSHA---GVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTF 439
TGGR+DV Y + C +C A G C+ CG V + P GL +V + L + NYTF
Sbjct: 358 TGGRQDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTF 417
Query: 440 EIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQ-EPDRPNGI 498
+EA NGVS L SV+++ A +++ K + L+W R G
Sbjct: 418 NVEAQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSPGA 477
Query: 499 ILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFE 558
L YE+ +D+E ++ E + L+P + Y+ ++R T G G FS EF
Sbjct: 478 NLTYELHVLNQDEERYQMVL---EPRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFR 534
Query: 559 TTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLI 618
T+P + +I + + +G LL +G+L+ S RA
Sbjct: 535 TSPPVSRGLTGGEIVAVIFGLLLGAALL---LGILVFRS------RRAQ----------- 574
Query: 619 WRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIE 678
+ +Q + ++ + KL ++ Y+D YEDP Q +F +E++ + + ++
Sbjct: 575 ------RQRQQRQRDRATDVDREDKL-WLKPYVDLQAYEDPAQGALDFTRELDPAWLMVD 627
Query: 679 RVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIH 738
VIG GEFGEV G L+LP + VAIKTLK Q +FL EA+IMGQF HP+I+H
Sbjct: 628 TVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILH 687
Query: 739 LEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVH 798
LEGVVTK KP+MI+TE+MENG+LD FL++ + Q QLV ML+GI++GM YLS+ YVH
Sbjct: 688 LEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVH 747
Query: 799 RDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSA 858
RDLAARNIL+N NL CKVSDFGL+R+L DD + Y T+GGKIPIRWTAPEAIA R FT+A
Sbjct: 748 RDLAARNILVNQNLCCKVSDFGLTRLL-DDFDGTYETQGGKIPIRWTAPEAIAHRIFTTA 806
Query: 859 SDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKE 918
SDVWS+GIVMWEV+S+G++PY EM+NQ+V+K++E+GYRLP P+DCPA LY+LM +CW +
Sbjct: 807 SDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYD 866
Query: 919 RNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIK 978
R RP F ++ L++L+ NP SL+T+ N R++ L S YR+V EWLE+I+
Sbjct: 867 RARRPHFQKLQAHLEQLLANPHSLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIR 926
Query: 979 MGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMK 1027
M RY F G +M+ V ++T EDL ++G+TL GHQK+I+ S+Q K
Sbjct: 927 MKRYILHFHSAGLDTMECVLELTAEDLTQMGITLPGHQKRILCSIQGFK 975
>gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]
Length = 1021
Score = 756 bits (1953), Expect = 0.0
Identities = 411/1038 (39%), Positives = 603/1038 (58%), Gaps = 91/1038 (8%)
Query: 40 LWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTY 99
LW LL+ + L E LLD+ ++GW+ +P GW+E+ +D+ T+
Sbjct: 20 LWVLLLVSSVLAL-------EEVLLDTTGETSEIGWLTYPPGGWDEVSVLDDQRRLTRTF 72
Query: 100 QVCKVMEQ----NQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYY 155
+ C V Q+NWL T ++ GA R I L F++R C+SL GTC+ETF +YY
Sbjct: 73 EACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYY 132
Query: 156 FESDDQNGRNIKENQYIK----IDTIAADESFTELD-----------------LGDRV-M 193
++++ + + + ++K +DTIAADESF G R +
Sbjct: 133 RQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPHGAGQRAGL 192
Query: 194 KLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDT-ITGADS 252
+LN + R GPL+++GFY+AFQD GAC+ALV+VR++ CP+V+R A FP+T +GA
Sbjct: 193 QLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQASGAGG 252
Query: 253 SQLLEVSGSCVNHSVTDE----------PPKMHCSAEGEWLVPIGKCMCKAGYEEKNG-- 300
+ L+ G+CV H+ +E PP++HC+ EG+W+V +G C C+ GY+ G
Sbjct: 253 ASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDK 312
Query: 301 TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA 360
CQ C G +K+S C CP S+ A+ C C + ++R SDPP CT PPSA
Sbjct: 313 ACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSA 372
Query: 361 PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSH-------AGVCEECGGHVR 413
P+ V +++ L W P + GGR D+ + + CK+C G C C V
Sbjct: 373 PQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVH 432
Query: 414 YLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVT 473
+ PRQ GL + V++ L AH Y E++AVNGVS+LSP Q ++NV+T+ PS V
Sbjct: 433 FDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVP 492
Query: 474 NVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKET-TITAEGLKP 532
V + A NSI++SW +PD+ NG IL+Y+++Y+++ ++ S++ + ET T T L P
Sbjct: 493 VVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLTSETNTATVTQLSP 552
Query: 533 ASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGV 592
+Y FQ+RARTAAG+G + + F+T P SS Q+P +S+ +G IL A+ +
Sbjct: 553 GHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSS---QLPE-RLSLVIGSILGALAFLL 608
Query: 593 LLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYID 652
L A ++ AV GY++ Q + GV+ YID
Sbjct: 609 LA-----------AITVLAVVFQRKRRGTGYTEQLQQYSSPGL----------GVKYYID 647
Query: 653 PHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVG 712
P TYEDP QA+ E A+E++ + I IE VIG G FGEV GRL+ G+RE VAI+ L G
Sbjct: 648 PSTYEDPCQAIRELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAG 707
Query: 713 YTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQF 772
E + FLG A+++GQF HPNI+ LEGVVTKS+P+M++TE+ME G LD+FL++ +GQF
Sbjct: 708 GAESLQMTFLGRAAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQF 767
Query: 773 TVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAA 832
+ +QLV M RG++A M+YLS +VHR L+A ++L+NS+LVCKV+ G
Sbjct: 768 SSLQLVAMQRGVAAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLG------------ 815
Query: 833 YTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVE 892
++ +G +RW APE IA K T++SDVWS+GI+MWEV+SYGERPYW+M+ Q+V+ A+E
Sbjct: 816 HSPQGPSCLLRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIE 875
Query: 893 EGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRV 952
+ +RLP P CP L+ LMLD WQK+R RP FD++V DK+IR P +L+ + R
Sbjct: 876 QEFRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERP 935
Query: 953 SNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTL 1012
S L L S WL AI + Y + F + G + VAQ++LEDL LG+TL
Sbjct: 936 SQALLTPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITL 995
Query: 1013 VGHQKKIMNSLQEMKVQL 1030
GHQKK+++ +Q ++ L
Sbjct: 996 AGHQKKLLHHIQLLQQHL 1013
>gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo
sapiens]
Length = 539
Score = 737 bits (1902), Expect = 0.0
Identities = 339/522 (64%), Positives = 423/522 (81%), Gaps = 5/522 (0%)
Query: 44 LLLCAALRT---LLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQ 100
LL C+ L + L+ PSNEVNLLDS+T+ G+LGWI++P +GWEEI VDE+Y PI TYQ
Sbjct: 10 LLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQ 69
Query: 101 VCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDD 160
VC VM+ +QNNWL T+W+ A +I++ELKFTLRDCNS+P LGTCKETFN+YY ESDD
Sbjct: 70 VCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDD 129
Query: 161 QNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGAC 220
+G +E+Q+ KIDTIAADESFT++DLGDR++KLNTE+R+VGP++KKGFYLAFQDVGAC
Sbjct: 130 DHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGAC 189
Query: 221 IALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEG 280
+ALVSVRVY+KKCP V++LA+FPDT+ DS L+EV GSCVN+S ++PP+M+CS EG
Sbjct: 190 VALVSVRVYFKKCPFTVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEG 248
Query: 281 EWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEK 340
EWLVPIGKC C AGYEE+ CQ CRPGF+KA C KCPPHS T E+ S +C CE
Sbjct: 249 EWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCEN 308
Query: 341 DYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNS 400
+YFR + DPP+MACTRPPS+PRN ISN+NETSV L+W P DTGGRKDV++ I CKKC
Sbjct: 309 NYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGW 368
Query: 401 HAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSV 460
+ CE C +VR+LPRQ GL NT+V + DLLAHTNYTFEI+AVNGVS+LS RQ+ +V
Sbjct: 369 NIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAV 428
Query: 461 NVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEK-DQETSYTIIK 519
++TTNQAAPSPV +KK + ++NSISLSWQEP+ PNGIIL+YE+KY+EK +QETSYTI++
Sbjct: 429 SITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILR 488
Query: 520 SKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTP 561
++ T +T LKP ++YVFQIRARTAAGYG SR+FEFET+P
Sbjct: 489 ARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSP 530
>gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo
sapiens]
Length = 495
Score = 555 bits (1430), Expect = e-158
Identities = 253/428 (59%), Positives = 322/428 (75%), Gaps = 1/428 (0%)
Query: 40 LWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTY 99
LW + AA T +++ EVNLLD+ T+ GD GW+ +P +GW+ I EVDE++ PIHTY
Sbjct: 12 LWV-VTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTY 70
Query: 100 QVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESD 159
QVC VM NQNNWL TSW+ +GA R++ E+KFTLRDCNS+PG LGTCKETFN+YY ESD
Sbjct: 71 QVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESD 130
Query: 160 DQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGA 219
G + +E+Q++KIDTIAADESFT DLG R +KLNTEVR VGPLSK+GFYLAFQD+GA
Sbjct: 131 RDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGA 190
Query: 220 CIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAE 279
C+A++S+R+YYKKCP++VR+LA F + +TGADSS L+EV G CV HS + PKM+CSAE
Sbjct: 191 CLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAE 250
Query: 280 GEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCE 339
GEWLVPIGKC+C AGYEE+ C C GF+K++P Q C +CPPHS++ A+ +C C+
Sbjct: 251 GEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCD 310
Query: 340 KDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCN 399
Y+R DPP+ ACTRPPSAP N IS+VN TSV LEW PP D GGR D++Y C++C
Sbjct: 311 LSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCP 370
Query: 400 SHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVS 459
CE CG R++P+Q+ L S+++ +LLAH NY+F IEAVNGVSDLSP R+
Sbjct: 371 WALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAV 430
Query: 460 VNVTTNQA 467
VN+TTNQA
Sbjct: 431 VNITTNQA 438
>gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]
Length = 295
Score = 318 bits (814), Expect = 2e-86
Identities = 158/279 (56%), Positives = 200/279 (71%), Gaps = 8/279 (2%)
Query: 33 SAPRRAPLWTCLL-LCAALRTLLASP--SNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEV 89
+ P L+ C + LC AL P + EV LLDS+ +LGW A P NGWEEI V
Sbjct: 5 AGPHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGV 64
Query: 90 DENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKE 149
DE+ PI TYQVC V+E NQ+NWL T WIS RIF+EL+FTLRDC+S+PG GTCKE
Sbjct: 65 DEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKE 124
Query: 150 TFNMYYFESDDQNGR---NIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLS 206
TFN+YY E++ GR + ++ KIDTIAADESFT+ DLG+R MKLNTEVR++GPLS
Sbjct: 125 TFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLS 184
Query: 207 KKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHS 266
++GF+LAFQDVGAC+ALVSVRVYYK+C + VR LA FP T + S L+EV+G+CV HS
Sbjct: 185 RRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHS 244
Query: 267 VTD--EPPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQ 303
+ PP+MHC A+GEWLVP+G+C C AG++E+ C+
Sbjct: 245 EGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCE 283
>gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]
Length = 526
Score = 229 bits (583), Expect = 1e-59
Identities = 120/277 (43%), Positives = 175/277 (63%), Gaps = 12/277 (4%)
Query: 659 PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQR 718
P + + A EI + +E+ +GAG+FGEV + VA+KT+K G +
Sbjct: 246 PQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYN----KHTKVAVKTMKPGSMSVEA 301
Query: 719 RDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVI-QL 777
FL EA++M H ++ L VVTK +P+ I+TE+M GSL FLK ++G + +L
Sbjct: 302 --FLAEANVMKTLQHDKLVKLHAVVTK-EPIYIITEFMAKGSLLDFLKSDEGSKQPLPKL 358
Query: 778 VGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTR- 836
+ I+ GM ++ Y+HRDL A NIL++++LVCK++DFGL+RV+ED+ YT R
Sbjct: 359 IDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNE---YTARE 415
Query: 837 GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYR 896
G K PI+WTAPEAI F FT SDVWS+GI++ E+V+YG PY M+N +VI+A+E GYR
Sbjct: 416 GAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYR 475
Query: 897 LPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 933
+P P +CP LY +M+ CW+ RP F+ I ++LD
Sbjct: 476 MPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLD 512
>gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
isoform B [Homo sapiens]
Length = 491
Score = 226 bits (577), Expect = 7e-59
Identities = 121/277 (43%), Positives = 175/277 (63%), Gaps = 11/277 (3%)
Query: 659 PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQR 718
P + + A EI I + + +GAG+FGEV G K VA+KTLK G Q
Sbjct: 210 PQKPWDKDAWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK----VAVKTLKPGTMSVQA 265
Query: 719 RDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVI-QL 777
FL EA++M H ++ L VVT+ +P+ I+TEYM GSL FLK ++G ++ +L
Sbjct: 266 --FLEEANLMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKL 323
Query: 778 VGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTR- 836
+ I+ GM Y+ Y+HRDL A N+L++ +L+CK++DFGL+RV+ED+ YT R
Sbjct: 324 IDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE---YTARE 380
Query: 837 GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYR 896
G K PI+WTAPEAI F FT SDVWS+GI+++E+V+YG+ PY TN DV+ A+ +GYR
Sbjct: 381 GAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYR 440
Query: 897 LPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 933
+P +CP LY +M CW+++ RP FD + ++LD
Sbjct: 441 MPRVENCPDELYDIMKMCWKEKAEERPTFDYLQSVLD 477
>gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
isoform A [Homo sapiens]
Length = 512
Score = 226 bits (577), Expect = 7e-59
Identities = 121/277 (43%), Positives = 175/277 (63%), Gaps = 11/277 (3%)
Query: 659 PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQR 718
P + + A EI I + + +GAG+FGEV G K VA+KTLK G Q
Sbjct: 231 PQKPWDKDAWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK----VAVKTLKPGTMSVQA 286
Query: 719 RDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVI-QL 777
FL EA++M H ++ L VVT+ +P+ I+TEYM GSL FLK ++G ++ +L
Sbjct: 287 --FLEEANLMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKL 344
Query: 778 VGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTR- 836
+ I+ GM Y+ Y+HRDL A N+L++ +L+CK++DFGL+RV+ED+ YT R
Sbjct: 345 IDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE---YTARE 401
Query: 837 GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYR 896
G K PI+WTAPEAI F FT SDVWS+GI+++E+V+YG+ PY TN DV+ A+ +GYR
Sbjct: 402 GAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYR 461
Query: 897 LPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 933
+P +CP LY +M CW+++ RP FD + ++LD
Sbjct: 462 MPRVENCPDELYDIMKMCWKEKAEERPTFDYLQSVLD 498
>gi|4503787 fyn-related kinase [Homo sapiens]
Length = 505
Score = 223 bits (568), Expect = 7e-58
Identities = 116/275 (42%), Positives = 167/275 (60%), Gaps = 8/275 (2%)
Query: 669 EIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIM 728
EI+ + I + + +G+G+FGEV G PVA+KTLK G + DFL EA IM
Sbjct: 228 EIDRNSIQLLKRLGSGQFGEVWEGLWN----NTTPVAVKTLKPGSMDPN--DFLREAQIM 281
Query: 729 GQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDG-QFTVIQLVGMLRGISAG 787
HP +I L V T P+ I+TE M +GSL +L+ + G + + Q V M +++G
Sbjct: 282 KNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASG 341
Query: 788 MKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGG-KIPIRWTA 846
M YL Y+HRDLAARN+L+ + + KV+DFGL+RV + D E Y +R K+P++WTA
Sbjct: 342 MAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTA 401
Query: 847 PEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAA 906
PEAI KF+ SDVWS+GI+++E+++YG+ PY MT VI+ + + YRLP P +CP
Sbjct: 402 PEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQ 461
Query: 907 LYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSS 941
Y +ML+CW E RP F+ + L+ SS
Sbjct: 462 FYNIMLECWNAEPKERPTFETLRWKLEDYFETDSS 496
>gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]
Length = 543
Score = 223 bits (567), Expect = 1e-57
Identities = 126/281 (44%), Positives = 176/281 (62%), Gaps = 12/281 (4%)
Query: 655 TYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYT 714
T + Q + + A EI + +E +G G FGEV G K VAIKTLK G
Sbjct: 257 TVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK----VAIKTLKPGTM 312
Query: 715 EKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTV 774
+ FL EA IM + H ++ L VV++ +P+ IVTE+M GSL FLK+ DG++
Sbjct: 313 MPEA--FLQEAQIMKKLRHDKLVPLYAVVSE-EPIYIVTEFMSKGSLLDFLKEGDGKYLK 369
Query: 775 I-QLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAY 833
+ QLV M I+ GM Y+ M Y+HRDL A NIL+ NLVCK++DFGL+R++ED+ Y
Sbjct: 370 LPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNE---Y 426
Query: 834 TTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVE 892
T R G K PI+WTAPEA + +FT SDVWS+GI+ E+V+ G PY M N++V++ VE
Sbjct: 427 TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVE 486
Query: 893 EGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 933
GYR+P P CP +L++LM CW+K+ + RP F+ I + L+
Sbjct: 487 RGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 527
>gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]
Length = 1074
Score = 222 bits (566), Expect = 1e-57
Identities = 116/268 (43%), Positives = 161/268 (60%), Gaps = 3/268 (1%)
Query: 669 EIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIM 728
EI+ I + R IG G+FG+V G P L VAIKT K ++ R FL EA M
Sbjct: 438 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTM 497
Query: 729 GQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGM 788
QFDHP+I+ L GV+T++ PV I+ E G L +FL+ + L+ +S +
Sbjct: 498 RQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 556
Query: 789 KYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPE 848
YL +VHRD+AARN+L++SN K+ DFGLSR +ED Y GK+PI+W APE
Sbjct: 557 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--TYYKASKGKLPIKWMAPE 614
Query: 849 AIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALY 908
+I FR+FTSASDVW +G+ MWE++ +G +P+ + N DVI +E G RLP P +CP LY
Sbjct: 615 SINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLY 674
Query: 909 QLMLDCWQKERNSRPKFDEIVNMLDKLI 936
LM CW + + RP+F E+ L ++
Sbjct: 675 SLMTKCWAYDPSRRPRFTELKAQLSTIL 702
>gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]
Length = 1052
Score = 222 bits (566), Expect = 1e-57
Identities = 116/268 (43%), Positives = 161/268 (60%), Gaps = 3/268 (1%)
Query: 669 EIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIM 728
EI+ I + R IG G+FG+V G P L VAIKT K ++ R FL EA M
Sbjct: 416 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTM 475
Query: 729 GQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGM 788
QFDHP+I+ L GV+T++ PV I+ E G L +FL+ + L+ +S +
Sbjct: 476 RQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 534
Query: 789 KYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPE 848
YL +VHRD+AARN+L++SN K+ DFGLSR +ED Y GK+PI+W APE
Sbjct: 535 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--TYYKASKGKLPIKWMAPE 592
Query: 849 AIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALY 908
+I FR+FTSASDVW +G+ MWE++ +G +P+ + N DVI +E G RLP P +CP LY
Sbjct: 593 SINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLY 652
Query: 909 QLMLDCWQKERNSRPKFDEIVNMLDKLI 936
LM CW + + RP+F E+ L ++
Sbjct: 653 SLMTKCWAYDPSRRPRFTELKAQLSTIL 680
>gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]
Length = 537
Score = 222 bits (565), Expect = 2e-57
Identities = 118/267 (44%), Positives = 171/267 (64%), Gaps = 12/267 (4%)
Query: 669 EIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIM 728
EI + + + +G G+FGEV G K VAIKTLK G + FL EA IM
Sbjct: 265 EIPRESLQLIKRLGNGQFGEVWMGTWNGNTK----VAIKTLKPGTMSPE--SFLEEAQIM 318
Query: 729 GQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVI-QLVGMLRGISAG 787
+ H ++ L VV++ +P+ IVTEYM GSL FLK +G+ + LV M ++AG
Sbjct: 319 KKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 377
Query: 788 MKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTR-GGKIPIRWTA 846
M Y+ M Y+HRDL + NIL+ + L+CK++DFGL+R++ED+ YT R G K PI+WTA
Sbjct: 378 MAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE---YTARQGAKFPIKWTA 434
Query: 847 PEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAA 906
PEA + +FT SDVWS+GI++ E+V+ G PY M N++V++ VE GYR+P P DCP +
Sbjct: 435 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPIS 494
Query: 907 LYQLMLDCWQKERNSRPKFDEIVNMLD 933
L++LM+ CW+K+ RP F+ + + L+
Sbjct: 495 LHELMIHCWKKDPEERPTFEYLQSFLE 521
>gi|112789548 lymphocyte-specific protein tyrosine kinase precursor
[Homo sapiens]
Length = 509
Score = 221 bits (562), Expect = 4e-57
Identities = 122/283 (43%), Positives = 175/283 (61%), Gaps = 12/283 (4%)
Query: 653 PHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVG 712
P + P + E E+ + + +GAG+FGEV G K VA+K+LK G
Sbjct: 223 PCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTK----VAVKSLKQG 278
Query: 713 YTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDG-Q 771
FL EA++M Q H ++ L VVT+ +P+ I+TEYMENGSL FLK G +
Sbjct: 279 SMSPDA--FLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITEYMENGSLVDFLKTPSGIK 335
Query: 772 FTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEA 831
T+ +L+ M I+ GM ++ + Y+HRDL A NIL++ L CK++DFGL+R++ED+
Sbjct: 336 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE-- 393
Query: 832 AYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKA 890
YT R G K PI+WTAPEAI + FT SDVWS+GI++ E+V++G PY MTN +VI+
Sbjct: 394 -YTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQN 452
Query: 891 VEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 933
+E GYR+ P +CP LYQLM CW++ RP FD + ++L+
Sbjct: 453 LERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 495
>gi|112789546 lymphocyte-specific protein tyrosine kinase precursor
[Homo sapiens]
Length = 509
Score = 221 bits (562), Expect = 4e-57
Identities = 122/283 (43%), Positives = 175/283 (61%), Gaps = 12/283 (4%)
Query: 653 PHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVG 712
P + P + E E+ + + +GAG+FGEV G K VA+K+LK G
Sbjct: 223 PCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTK----VAVKSLKQG 278
Query: 713 YTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDG-Q 771
FL EA++M Q H ++ L VVT+ +P+ I+TEYMENGSL FLK G +
Sbjct: 279 SMSPDA--FLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITEYMENGSLVDFLKTPSGIK 335
Query: 772 FTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEA 831
T+ +L+ M I+ GM ++ + Y+HRDL A NIL++ L CK++DFGL+R++ED+
Sbjct: 336 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE-- 393
Query: 832 AYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKA 890
YT R G K PI+WTAPEAI + FT SDVWS+GI++ E+V++G PY MTN +VI+
Sbjct: 394 -YTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQN 452
Query: 891 VEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 933
+E GYR+ P +CP LYQLM CW++ RP FD + ++L+
Sbjct: 453 LERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 495
>gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo
sapiens]
Length = 536
Score = 220 bits (561), Expect = 5e-57
Identities = 125/281 (44%), Positives = 172/281 (61%), Gaps = 12/281 (4%)
Query: 655 TYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYT 714
T + Q + + A EI + +E +G G FGEV G + VAIKTLK G
Sbjct: 250 TSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR----VAIKTLKPGTM 305
Query: 715 EKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTV 774
+ FL EA +M + H ++ L VV++ +P+ IVTEYM GSL FLK G++
Sbjct: 306 SPEA--FLQEAQVMKKLRHEKLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKGETGKYLR 362
Query: 775 I-QLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAY 833
+ QLV M I++GM Y+ M YVHRDL A NIL+ NLVCKV+DFGL+R++ED+ Y
Sbjct: 363 LPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE---Y 419
Query: 834 TTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVE 892
T R G K PI+WTAPEA + +FT SDVWS+GI++ E+ + G PY M N++V+ VE
Sbjct: 420 TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE 479
Query: 893 EGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 933
GYR+P P +CP +L+ LM CW+KE RP F+ + L+
Sbjct: 480 RGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLE 520
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,582,207
Number of Sequences: 37866
Number of extensions: 2044290
Number of successful extensions: 9536
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 607
Number of HSP's successfully gapped in prelim test: 355
Number of HSP's that attempted gapping in prelim test: 5711
Number of HSP's gapped (non-prelim): 2184
length of query: 1037
length of database: 18,247,518
effective HSP length: 112
effective length of query: 925
effective length of database: 14,006,526
effective search space: 12956036550
effective search space used: 12956036550
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.