BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|221316707 NADPH dependent diflavin oxidoreductase 1 isoform d [Homo sapiens] (521 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|221316707 NADPH dependent diflavin oxidoreductase 1 isoform d... 1058 0.0 gi|7657393 NADPH dependent diflavin oxidoreductase 1 isoform b [... 1013 0.0 gi|221316705 NADPH dependent diflavin oxidoreductase 1 isoform a... 1006 0.0 gi|221316709 NADPH dependent diflavin oxidoreductase 1 isoform c... 992 0.0 gi|127139033 cytochrome P450 reductase [Homo sapiens] 258 1e-68 gi|40254422 nitric oxide synthase 3 isoform 1 [Homo sapiens] 182 5e-46 gi|24041029 nitric oxide synthase 2A [Homo sapiens] 176 5e-44 gi|10835173 nitric oxide synthase 1, neuronal [Homo sapiens] 154 2e-37 gi|169790958 methionine synthase reductase isoform 1 [Homo sapiens] 145 9e-35 gi|169790956 methionine synthase reductase isoform 2 [Homo sapiens] 145 9e-35 gi|231571329 nitric oxide synthase 3 isoform 3 [Homo sapiens] 60 6e-09 gi|231571356 nitric oxide synthase 3 isoform 4 [Homo sapiens] 57 3e-08 gi|231571314 nitric oxide synthase 3 isoform 2 [Homo sapiens] 57 3e-08 gi|50726981 radical S-adenosyl methionine and flavodoxin domains... 47 4e-05 gi|224282123 tRNA-yW synthesizing protein 1 homolog B isoform 1 ... 35 0.17 gi|27312029 hypothetical protein LOC145376 [Homo sapiens] 33 0.48 gi|145587088 hypothetical protein LOC165186 [Homo sapiens] 33 0.83 gi|89242137 Meckel syndrome, type 1 [Homo sapiens] 30 7.0 gi|223468693 hypothetical protein LOC100130361 [Homo sapiens] 29 9.1 gi|223468690 hypothetical protein LOC100132994 [Homo sapiens] 29 9.1 gi|124028529 symplekin [Homo sapiens] 29 9.1 gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens] 29 9.1 gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens] 29 9.1 >gi|221316707 NADPH dependent diflavin oxidoreductase 1 isoform d [Homo sapiens] Length = 521 Score = 1058 bits (2737), Expect = 0.0 Identities = 521/521 (100%), Positives = 521/521 (100%) Query: 1 MPSPQLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCAT 60 MPSPQLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCAT Sbjct: 1 MPSPQLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCAT 60 Query: 61 TGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLG 120 TGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLG Sbjct: 61 TGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLG 120 Query: 121 GSALLPVCLGDDQHELGLPSKFTLLFLQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMI 180 GSALLPVCLGDDQHELGLPSKFTLLFLQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMI Sbjct: 121 GSALLPVCLGDDQHELGLPSKFTLLFLQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMI 180 Query: 181 SNQRVTGPSHFQDVRLIEFDILGSGISFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLF 240 SNQRVTGPSHFQDVRLIEFDILGSGISFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLF Sbjct: 181 SNQRVTGPSHFQDVRLIEFDILGSGISFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLF 240 Query: 241 MLQPREPDVSSPTRLPQPCSMRHLVSHYLDIASVPRRSFFELLACLSLHELEREKLLEFS 300 MLQPREPDVSSPTRLPQPCSMRHLVSHYLDIASVPRRSFFELLACLSLHELEREKLLEFS Sbjct: 241 MLQPREPDVSSPTRLPQPCSMRHLVSHYLDIASVPRRSFFELLACLSLHELEREKLLEFS 300 Query: 301 SAQGQEELFEYCNRPRRTILEVLCDFPHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHP 360 SAQGQEELFEYCNRPRRTILEVLCDFPHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHP Sbjct: 301 SAQGQEELFEYCNRPRRTILEVLCDFPHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHP 360 Query: 361 SRLQILVAVVQFQTRLKEPRRGLCSSWLASLDPGQGPVRVPLWVRPGSLAFPETPDTPVI 420 SRLQILVAVVQFQTRLKEPRRGLCSSWLASLDPGQGPVRVPLWVRPGSLAFPETPDTPVI Sbjct: 361 SRLQILVAVVQFQTRLKEPRRGLCSSWLASLDPGQGPVRVPLWVRPGSLAFPETPDTPVI 420 Query: 421 MVGPGTGVAPFRAAIQERVAQGQTGNFLFFGCRWRDQDFYWEAEWQELEKRDCLTLIPAF 480 MVGPGTGVAPFRAAIQERVAQGQTGNFLFFGCRWRDQDFYWEAEWQELEKRDCLTLIPAF Sbjct: 421 MVGPGTGVAPFRAAIQERVAQGQTGNFLFFGCRWRDQDFYWEAEWQELEKRDCLTLIPAF 480 Query: 481 SREQEQKVYVQHRLRELGSLVWELLDRQATPSPCQRTSRKP 521 SREQEQKVYVQHRLRELGSLVWELLDRQATPSPCQRTSRKP Sbjct: 481 SREQEQKVYVQHRLRELGSLVWELLDRQATPSPCQRTSRKP 521 >gi|7657393 NADPH dependent diflavin oxidoreductase 1 isoform b [Homo sapiens] Length = 597 Score = 1013 bits (2620), Expect = 0.0 Identities = 508/542 (93%), Positives = 508/542 (93%), Gaps = 34/542 (6%) Query: 1 MPSPQLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCAT 60 MPSPQLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCAT Sbjct: 1 MPSPQLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCAT 60 Query: 61 TGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLG 120 TGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLG Sbjct: 61 TGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLG 120 Query: 121 GSALLPVCLGDDQHELG----------------------------------LPSKFTLLF 146 GSALLPVCLGDDQHELG LPSKFTLLF Sbjct: 121 GSALLPVCLGDDQHELGPDAAVDPWLRDLWDRVLGLYPPPPGLTEIPPGVPLPSKFTLLF 180 Query: 147 LQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRLIEFDILGSGI 206 LQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRLIEFDILGSGI Sbjct: 181 LQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRLIEFDILGSGI 240 Query: 207 SFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFMLQPREPDVSSPTRLPQPCSMRHLVS 266 SFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFMLQPREPDVSSPTRLPQPCSMRHLVS Sbjct: 241 SFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFMLQPREPDVSSPTRLPQPCSMRHLVS 300 Query: 267 HYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDF 326 HYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDF Sbjct: 301 HYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDF 360 Query: 327 PHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTRLKEPRRGLCSS 386 PHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTRLKEPRRGLCSS Sbjct: 361 PHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTRLKEPRRGLCSS 420 Query: 387 WLASLDPGQGPVRVPLWVRPGSLAFPETPDTPVIMVGPGTGVAPFRAAIQERVAQGQTGN 446 WLASLDPGQGPVRVPLWVRPGSLAFPETPDTPVIMVGPGTGVAPFRAAIQERVAQGQTGN Sbjct: 421 WLASLDPGQGPVRVPLWVRPGSLAFPETPDTPVIMVGPGTGVAPFRAAIQERVAQGQTGN 480 Query: 447 FLFFGCRWRDQDFYWEAEWQELEKRDCLTLIPAFSREQEQKVYVQHRLRELGSLVWELLD 506 FLFFGCRWRDQDFYWEAEWQELEKRDCLTLIPAFSREQEQKVYVQHRLRELGSLVWELLD Sbjct: 481 FLFFGCRWRDQDFYWEAEWQELEKRDCLTLIPAFSREQEQKVYVQHRLRELGSLVWELLD 540 Query: 507 RQ 508 RQ Sbjct: 541 RQ 542 >gi|221316705 NADPH dependent diflavin oxidoreductase 1 isoform a [Homo sapiens] Length = 606 Score = 1006 bits (2600), Expect = 0.0 Identities = 508/551 (92%), Positives = 508/551 (92%), Gaps = 43/551 (7%) Query: 1 MPSPQLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCAT 60 MPSPQLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCAT Sbjct: 1 MPSPQLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCAT 60 Query: 61 TGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLG 120 TGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLG Sbjct: 61 TGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLG 120 Query: 121 GSALLPVCLGDDQHELG----------------------------------LPSKFTLLF 146 GSALLPVCLGDDQHELG LPSKFTLLF Sbjct: 121 GSALLPVCLGDDQHELGPDAAVDPWLRDLWDRVLGLYPPPPGLTEIPPGVPLPSKFTLLF 180 Query: 147 LQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRLIEFDILGSGI 206 LQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRLIEFDILGSGI Sbjct: 181 LQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRLIEFDILGSGI 240 Query: 207 SFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFMLQPREPDVSSPTRLPQPCSMRHLVS 266 SFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFMLQPREPDVSSPTRLPQPCSMRHLVS Sbjct: 241 SFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFMLQPREPDVSSPTRLPQPCSMRHLVS 300 Query: 267 HYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDF 326 HYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDF Sbjct: 301 HYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDF 360 Query: 327 PHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTRLKEPRRGLCSS 386 PHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTRLKEPRRGLCSS Sbjct: 361 PHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTRLKEPRRGLCSS 420 Query: 387 WLASLDPGQGPVRVPLWVRPGSLAFPETPDTPVIMVGPGTGVAPFRAAIQERVAQGQTGN 446 WLASLDPGQGPVRVPLWVRPGSLAFPETPDTPVIMVGPGTGVAPFRAAIQERVAQGQTGN Sbjct: 421 WLASLDPGQGPVRVPLWVRPGSLAFPETPDTPVIMVGPGTGVAPFRAAIQERVAQGQTGN 480 Query: 447 FLFFGCRWRDQDFYWEAEWQELEKRDCLTLIPAFSRE---------QEQKVYVQHRLREL 497 FLFFGCRWRDQDFYWEAEWQELEKRDCLTLIPAFSRE QEQKVYVQHRLREL Sbjct: 481 FLFFGCRWRDQDFYWEAEWQELEKRDCLTLIPAFSREQPPALFSALQEQKVYVQHRLREL 540 Query: 498 GSLVWELLDRQ 508 GSLVWELLDRQ Sbjct: 541 GSLVWELLDRQ 551 >gi|221316709 NADPH dependent diflavin oxidoreductase 1 isoform c [Homo sapiens] Length = 590 Score = 992 bits (2564), Expect = 0.0 Identities = 501/542 (92%), Positives = 501/542 (92%), Gaps = 41/542 (7%) Query: 1 MPSPQLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCAT 60 MPSPQLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCAT Sbjct: 1 MPSPQLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCAT 60 Query: 61 TGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLG 120 TGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLG Sbjct: 61 TGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLG 120 Query: 121 GSALLPVCLGDDQHELG----------------------------------LPSKFTLLF 146 GSALLPVCLGDDQHELG LPSKFTLLF Sbjct: 121 GSALLPVCLGDDQHELGPDAAVDPWLRDLWDRVLGLYPPPPGLTEIPPGVPLPSKFTLLF 180 Query: 147 LQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRLIEFDILGSGI 206 LQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRLIEFDILGSGI Sbjct: 181 LQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRLIEFDILGSGI 240 Query: 207 SFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFMLQPREPDVSSPTRLPQPCSMRHLVS 266 SFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFMLQPREPDVSSPTRLPQPCSMRHLVS Sbjct: 241 SFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFMLQPREPDVSSPTRLPQPCSMRHLVS 300 Query: 267 HYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDF 326 HYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDF Sbjct: 301 HYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDF 360 Query: 327 PHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTRLKEPRRGLCSS 386 PHTAAAIPPDYLLDLIPVIRPRAFSIASSLL ILVAVVQFQTRLKEPRRGLCSS Sbjct: 361 PHTAAAIPPDYLLDLIPVIRPRAFSIASSLL-------ILVAVVQFQTRLKEPRRGLCSS 413 Query: 387 WLASLDPGQGPVRVPLWVRPGSLAFPETPDTPVIMVGPGTGVAPFRAAIQERVAQGQTGN 446 WLASLDPGQGPVRVPLWVRPGSLAFPETPDTPVIMVGPGTGVAPFRAAIQERVAQGQTGN Sbjct: 414 WLASLDPGQGPVRVPLWVRPGSLAFPETPDTPVIMVGPGTGVAPFRAAIQERVAQGQTGN 473 Query: 447 FLFFGCRWRDQDFYWEAEWQELEKRDCLTLIPAFSREQEQKVYVQHRLRELGSLVWELLD 506 FLFFGCRWRDQDFYWEAEWQELEKRDCLTLIPAFSREQEQKVYVQHRLRELGSLVWELLD Sbjct: 474 FLFFGCRWRDQDFYWEAEWQELEKRDCLTLIPAFSREQEQKVYVQHRLRELGSLVWELLD 533 Query: 507 RQ 508 RQ Sbjct: 534 RQ 535 >gi|127139033 cytochrome P450 reductase [Homo sapiens] Length = 680 Score = 258 bits (658), Expect = 1e-68 Identities = 180/550 (32%), Positives = 283/550 (51%), Gaps = 57/550 (10%) Query: 6 LLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNL-----INEPLVIFVCAT 60 ++V +GSQTGTA++ + RL ++A R + + Y + +L I+ LV+F AT Sbjct: 83 IIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDNALVVFCMAT 142 Query: 61 TGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLG 120 G+GDP DN ++F+ ++ ++ L + FAV GLG+ +Y FN + K + +RL QLG Sbjct: 143 YGEGDPTDNAQDFYDWLQETDVD---LSGVKFAVFGLGNKTYEHFNAMGKYVDKRLEQLG 199 Query: 121 GSALLPVCLGDDQHELGLPSKFTLLFLQEAPS---------TGSEGQ------------- 158 + + LGDD L F Q P+ TG E Sbjct: 200 AQRIFELGLGDDDGNL--EEDFITWREQFWPAVCEHFGVEATGEESSIRQYELVVHTDID 257 Query: 159 ----------RVAHPGSQEPPSESK-PFLAPMISNQRVTGPSHFQDVRLIEFDILGSGIS 207 R+ +Q+PP ++K PFLA + +N+++ + + + +E DI S I Sbjct: 258 AAKVYMGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQGTE-RHLMHLELDISDSKIR 316 Query: 208 FAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFMLQPREPDVSSPTRLPQPCSMRHLVSH 267 + +GD V + P+N +A V + ++LG D D + L + + + P P S R +++ Sbjct: 317 YESGDHVAVYPANDSALVNQLGKILGADLDVVMSLNNLDEESNKKHPFPCPTSYRTALTY 376 Query: 268 YLDIASVPRRSFFELLACLSLHELEREKL--LEFSSAQGQEELFEYCNRPRRTILEVLCD 325 YLDI + PR + LA + E+E L + SS +G+E + RR IL +L D Sbjct: 377 YLDITNPPRTNVLYELAQYASEPSEQELLRKMASSSGEGKELYLSWVVEARRHILAILQD 436 Query: 326 FPHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTRLKEPRRGLCS 385 P + P D+L +L+P ++ R +SIASS HP+ + I VV+++T+ +G+ + Sbjct: 437 CP--SLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVVVEYETKAGRINKGVAT 494 Query: 386 SWLASLDP---GQGPVRVPLWVRPGSLAFPETPDTPVIMVGPGTGVAPFRAAIQERVAQG 442 +WL + +P G VP++VR P TPVIMVGPGTGVAPF IQER Sbjct: 495 NWLRAKEPAGENGGRALVPMFVRKSQFRLPFKATTPVIMVGPGTGVAPFIGFIQERAWLR 554 Query: 443 QTG-----NFLFFGCRWRDQDFYWEAEWQELEKRDCLT-LIPAFSREQEQKVYVQHRLRE 496 Q G L++GCR D+D+ + E + + LT L AFSREQ KVYVQH L++ Sbjct: 555 QQGKEVGETLLYYGCRRSDEDYLYREELAQFHRDGALTQLNVAFSREQSHKVYVQHLLKQ 614 Query: 497 LGSLVWELLD 506 +W+L++ Sbjct: 615 DREHLWKLIE 624 >gi|40254422 nitric oxide synthase 3 isoform 1 [Homo sapiens] Length = 1203 Score = 182 bits (463), Expect = 5e-46 Identities = 179/597 (29%), Positives = 267/597 (44%), Gaps = 113/597 (18%) Query: 8 VLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCATTGQGDPP 67 +L+GS+TG AQ +++LGR R+ RV +D Y VV+L +E LV+ V +T G GDPP Sbjct: 522 ILYGSETGRAQSYAQQLGR-LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPP 580 Query: 68 DNMKNF---------------------------------------WRFIFRKNLPST--- 85 +N ++F WR RK S+ Sbjct: 581 ENGESFAAALMEMSGPYNSSPRPEQHKSYKIRFNSISCSDPLVSSWR---RKRKESSNTD 637 Query: 86 ---ALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGSALLPVCLGDDQHELGLPSKF 142 AL + F V GLG +Y F A+ + RL +LGG LL + GD+ G F Sbjct: 638 SAGALGTLRFCVFGLGSRAYPHFCAFARAVDTRLEELGGERLLQLGQGDEL--CGQEEAF 695 Query: 143 ---TLLFLQEAPST---GSEGQRVAHP--------------------GSQEPPS-----E 171 Q A T G + + A G Q P Sbjct: 696 RGWAQAAFQAACETFCVGEDAKAAARDIFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHR 755 Query: 172 SKPFLAPMISNQRVTGPSHFQDVRLIEFDILGS-GISFAAGDVVLIQPSNSAAHVQRFCQ 230 K F A + S + + + L+ D G G+ + GD + + P N V+ Sbjct: 756 RKMFQATIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLS 815 Query: 231 VLG-----LDPDQLFMLQPREPDVSSP-----TRLPQPCSMRHLVSHYLDIASVPRRSFF 280 + +P + L+ P P RLP PC++R ++ +LDI S P Sbjct: 816 RVEDPPAPTEPVAVEQLEKGSPGGPPPGWVRDPRLP-PCTLRQALTFFLDITSPPSPQLL 874 Query: 281 ELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDFPHTAAAIPPDYLLD 340 LL+ L+ E+++L S + E +++ P T+LEVL FP + A+P LL Sbjct: 875 RLLSTLAEEPREQQELEALSQDPRRYEEWKWFRCP--TLLEVLEQFP--SVALPAPLLLT 930 Query: 341 LIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTR--LKEPRRGLCSSWLASLDPGQGPV 398 +P+++PR +S++S+ THP + + VAV+ ++T+ L G+CS+WL+ L PG Sbjct: 931 QLPLLQPRYYSVSSAPSTHPGEIHLTVAVLAYRTQDGLGPLHYGVCSTWLSQLKPGDP-- 988 Query: 399 RVPLWVRPG-SLAFPETPDTPVIMVGPGTGVAPFRAAIQERV----AQG--QTGNFLFFG 451 VP ++R S P P P I+VGPGTG+APFR QER+ ++G T L FG Sbjct: 989 -VPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFRGFWQERLHDIESKGLQPTPMTLVFG 1047 Query: 452 CRWRDQDFYWEAEWQELEKRDCL-TLIPAFSREQEQ-KVYVQHRLR-ELGSLVWELL 505 CR D + E Q ++R ++ AFSRE + K YVQ LR EL + V +L Sbjct: 1048 CRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSREPDNPKTYVQDILRTELAAEVHRVL 1104 >gi|24041029 nitric oxide synthase 2A [Homo sapiens] Length = 1153 Score = 176 bits (446), Expect = 5e-44 Identities = 166/556 (29%), Positives = 265/556 (47%), Gaps = 70/556 (12%) Query: 5 QLLVLFGSQTGTAQDVSERLGREARRRRLGC----RVQALDSYPVVNLINEPLVIFVCAT 60 ++ +LF ++TG ++ ++ LG C +V +D Y + L E L++ V +T Sbjct: 538 RVTILFATETGKSEALAWDLGA-----LFSCAFNPKVVCMDKYRLSCLEEERLLLVVTST 592 Query: 61 TGQGDPPDNMKNFWRFIFR-KNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQL 119 G GD P N + + +F K L + + +AV GLG S Y +F A + ++L L Sbjct: 593 FGNGDCPGNGEKLKKSLFMLKELNN----KFRYAVFGLGSSMYPRFCAFAHDIDQKLSHL 648 Query: 120 GGSALLPVCLGDDQ--HELGLPSKFTLLFLQEAPSTGSEGQRVAH------------PGS 165 G S L P+ GD+ E S F + G++ P Sbjct: 649 GASQLTPMGEGDELSGQEDAFRSWAVQTFKAACETFDVRGKQHIQIPKLYTSNVTWDPHH 708 Query: 166 QEPPSESKP---------------FLAPMISNQRVTGPSHFQDVRLIEFDIL-GSGISFA 209 +S+P F + S Q + P+ + L+E G G+++ Sbjct: 709 YRLVQDSQPLDLSKALSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSCEDGQGLNYL 768 Query: 210 AGDVVLIQPSNSAAHVQRFCQ--VLGLDPDQLFMLQPREPDVS---SPTRLPQPCSMRHL 264 G+ + + P N A VQ + V G P Q L+ + S S RLP PCS+ Sbjct: 769 PGEHLGVCPGNQPALVQGILERVVDGPTPHQTVRLEALDESGSYWVSDKRLP-PCSLSQA 827 Query: 265 VSHYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLC 324 ++++LDI + P + + LA ++ E ER++L E + +++ N P T LEVL Sbjct: 828 LTYFLDITTPPTQLLLQKLAQVATEEPERQRL-EALCQPSEYSKWKFTNSP--TFLEVLE 884 Query: 325 DFPHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTRLKEP--RRG 382 +FP + + +LL +P+++PR +SI+SS P+ + + VAVV + TR + G Sbjct: 885 EFP--SLRVSAGFLLSQLPILKPRFYSISSSRDHTPTEIHLTVAVVTYHTRDGQGPLHHG 942 Query: 383 LCSSWLASLDPGQGPVRVPLWVRPGS-LAFPETPDTPVIMVGPGTGVAPFRAAIQERVAQ 441 +CS+WL SL P Q PV P +VR S PE P P I++GPGTG+APFR+ Q+R+ Sbjct: 943 VCSTWLNSLKP-QDPV--PCFVRNASGFHLPEDPSHPCILIGPGTGIAPFRSFWQQRLHD 999 Query: 442 GQTGNF------LFFGCRWRDQDFYWEAEWQELEKRDCLTLI-PAFSR-EQEQKVYVQHR 493 Q L FGCR D+D ++ E E+ ++ L + A+SR + KVYVQ Sbjct: 1000 SQHKGVRGGRMTLVFGCRRPDEDHIYQEEMLEMAQKGVLHAVHTAYSRLPGKPKVYVQDI 1059 Query: 494 LR-ELGSLVWELLDRQ 508 LR +L S V +L ++ Sbjct: 1060 LRQQLASEVLRVLHKE 1075 >gi|10835173 nitric oxide synthase 1, neuronal [Homo sapiens] Length = 1434 Score = 154 bits (388), Expect = 2e-37 Identities = 160/604 (26%), Positives = 254/604 (42%), Gaps = 121/604 (20%) Query: 8 VLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCATTGQGDPP 67 +L+ ++TG +Q ++ L E + +V +++ Y +V+L +E LV+ V +T G GDPP Sbjct: 762 ILYATETGKSQAYAKTLC-EIFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPP 820 Query: 68 DNMKNFWRFIFRKNLPSTA---------------------------------------LC 88 +N + F + P++ L Sbjct: 821 ENGEKFGCALMEMRHPNSVQEERKSYKVRFNSVSSYSDSQKSSGDGPDLRDNFESAGPLA 880 Query: 89 QMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGSALLPV--------------------- 127 + F+V GLG +Y F + L +LGG +L + Sbjct: 881 NVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVF 940 Query: 128 -------CLGDDQH------------ELGLPSKFTLLFLQEAPSTGSEGQRVAHPGSQEP 168 C+GDD + +KF L F+ EAP ++G H Sbjct: 941 KAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTFVAEAPEL-TQGLSNVH------ 993 Query: 169 PSESKPFLAPMISNQRVTGPSHFQDVRLIEFDILGSG-ISFAAGDVVLIQPSNSAAHVQR 227 + + A ++S Q + P + + GS + + GD + + P N V Sbjct: 994 --KKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGSQELQYQPGDHLGVFPGNHEDLVNA 1051 Query: 228 FCQVLGLDPD-----QLFMLQPREPDV------SSPTRLPQPCSMRHLVSHYLDIASVPR 276 + L P ++ +L+ R + + RLP PC++ +YLDI + P Sbjct: 1052 LIERLEDAPPVNQMVKVELLEERNTALGVISNWTDELRLP-PCTIFQAFKYYLDITTPPT 1110 Query: 277 RSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDFPHTAAAIPPD 336 + A L+ E E+++LL S + E +++ P TI+EVL +FP + +P Sbjct: 1111 PLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNP--TIVEVLEEFP--SIQMPAT 1166 Query: 337 YLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTRLKEP--RRGLCSSWLASLDPG 394 LL + +++PR +SI+SS +P + + VA+V ++TR E G+CSSWL + Sbjct: 1167 LLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRI--- 1223 Query: 395 QGPVRVPLWVRPG-SLAFPETPDTPVIMVGPGTGVAPFRAAIQERVAQGQTGNF------ 447 Q VP +VR S P P P I+VGPGTG+APFR+ Q+R Q Sbjct: 1224 QADELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNPCPMV 1283 Query: 448 LFFGCRWRDQD-FYWEAEWQELEKRDCLTLIPAFSREQEQ-KVYVQHRLRE-LGSLVWEL 504 L FGCR D Y E Q K L A+SRE ++ K YVQ L+E L V+ Sbjct: 1284 LVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAESVYRA 1343 Query: 505 LDRQ 508 L Q Sbjct: 1344 LKEQ 1347 >gi|169790958 methionine synthase reductase isoform 1 [Homo sapiens] Length = 698 Score = 145 bits (366), Expect = 9e-35 Identities = 117/408 (28%), Positives = 188/408 (46%), Gaps = 50/408 (12%) Query: 137 GLPSKFTLLFLQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRL 196 GLP ++ + LQE S G E +V+ S F P+ ++T + L Sbjct: 244 GLPPEYLQVHLQE--SLGQEESQVS------VTSADPVFQVPISKAVQLTTNDAIKTTLL 295 Query: 197 IEFDILGSGISFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFML------QPREPDVS 250 +E DI + S+ GD + NS + VQ Q L L+ + + ++ + Sbjct: 296 VELDISNTDFSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLKIKADTKKKGAT 355 Query: 251 SPTRLPQPCSMRHLVSHYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFE 310 P +P CS++ + + L+I ++P+++F L + E+ +L E S QG + Sbjct: 356 LPQHIPAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSR 415 Query: 311 YCNRPRRTILEVLCDFPHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVV 370 + +L++L FP + P LL+ +P ++PR +S ASS L HP +L + +V Sbjct: 416 FVRDACACLLDLLLAFP--SCQPPLSLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIV 473 Query: 371 QFQTRLKEP--RRGLCSSWLASL--------------DPGQGPVRVPLWVRP---GSLAF 411 +F + R+G+C+ WLA L D G+ + + + P S Sbjct: 474 EFLSTATTEVLRKGVCTGWLALLVASVLQPNIHASHEDSGKA-LAPKISISPRTTNSFHL 532 Query: 412 PETPDTPVIMVGPGTGVAPFRAAIQER---VAQGQTGNF----LFFGCRWRDQDFYWEAE 464 P+ P P+IMVGPGTG+APF +Q R Q GNF LFFGCR +D+D+ + E Sbjct: 533 PDDPSIPIIMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFRKE 592 Query: 465 WQELEKRDCLT-LIPAFSR------EQEQKVYVQHRLRELGSLVWELL 505 + K LT L +FSR E+ YVQ ++ G V +L Sbjct: 593 LRHFLKHGILTHLKVSFSRDAPVGEEEAPAKYVQDNIQLHGQQVARIL 640 Score = 62.4 bits (150), Expect = 1e-09 Identities = 40/130 (30%), Positives = 63/130 (48%), Gaps = 3/130 (2%) Query: 5 QLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINE--PLVIFVCATTG 62 + L+L+ +Q G A+ ++E + +A + + +L E PLV+ V +TTG Sbjct: 3 RFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVV-STTG 61 Query: 63 QGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGS 122 GDPPD + F + I + LP + + +LGLGDS Y F K + +RL +LG Sbjct: 62 TGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGAR 121 Query: 123 ALLPVCLGDD 132 DD Sbjct: 122 HFYDTGHADD 131 >gi|169790956 methionine synthase reductase isoform 2 [Homo sapiens] Length = 725 Score = 145 bits (366), Expect = 9e-35 Identities = 117/408 (28%), Positives = 188/408 (46%), Gaps = 50/408 (12%) Query: 137 GLPSKFTLLFLQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRL 196 GLP ++ + LQE S G E +V+ S F P+ ++T + L Sbjct: 271 GLPPEYLQVHLQE--SLGQEESQVS------VTSADPVFQVPISKAVQLTTNDAIKTTLL 322 Query: 197 IEFDILGSGISFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFML------QPREPDVS 250 +E DI + S+ GD + NS + VQ Q L L+ + + ++ + Sbjct: 323 VELDISNTDFSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLKIKADTKKKGAT 382 Query: 251 SPTRLPQPCSMRHLVSHYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFE 310 P +P CS++ + + L+I ++P+++F L + E+ +L E S QG + Sbjct: 383 LPQHIPAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSR 442 Query: 311 YCNRPRRTILEVLCDFPHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVV 370 + +L++L FP + P LL+ +P ++PR +S ASS L HP +L + +V Sbjct: 443 FVRDACACLLDLLLAFP--SCQPPLSLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIV 500 Query: 371 QFQTRLKEP--RRGLCSSWLASL--------------DPGQGPVRVPLWVRP---GSLAF 411 +F + R+G+C+ WLA L D G+ + + + P S Sbjct: 501 EFLSTATTEVLRKGVCTGWLALLVASVLQPNIHASHEDSGKA-LAPKISISPRTTNSFHL 559 Query: 412 PETPDTPVIMVGPGTGVAPFRAAIQER---VAQGQTGNF----LFFGCRWRDQDFYWEAE 464 P+ P P+IMVGPGTG+APF +Q R Q GNF LFFGCR +D+D+ + E Sbjct: 560 PDDPSIPIIMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFRKE 619 Query: 465 WQELEKRDCLT-LIPAFSR------EQEQKVYVQHRLRELGSLVWELL 505 + K LT L +FSR E+ YVQ ++ G V +L Sbjct: 620 LRHFLKHGILTHLKVSFSRDAPVGEEEAPAKYVQDNIQLHGQQVARIL 667 Score = 62.4 bits (150), Expect = 1e-09 Identities = 40/130 (30%), Positives = 63/130 (48%), Gaps = 3/130 (2%) Query: 5 QLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINE--PLVIFVCATTG 62 + L+L+ +Q G A+ ++E + +A + + +L E PLV+ V +TTG Sbjct: 30 RFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVV-STTG 88 Query: 63 QGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGS 122 GDPPD + F + I + LP + + +LGLGDS Y F K + +RL +LG Sbjct: 89 TGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGAR 148 Query: 123 ALLPVCLGDD 132 DD Sbjct: 149 HFYDTGHADD 158 >gi|231571329 nitric oxide synthase 3 isoform 3 [Homo sapiens] Length = 614 Score = 59.7 bits (143), Expect = 6e-09 Identities = 34/82 (41%), Positives = 49/82 (59%), Gaps = 2/82 (2%) Query: 8 VLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCATTGQGDPP 67 +L+GS+TG AQ +++LGR R+ RV +D Y VV+L +E LV+ V +T G GDPP Sbjct: 522 ILYGSETGRAQSYAQQLGR-LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPP 580 Query: 68 DNMKNFWRFIFRKNLPSTALCQ 89 +N + W F L S + Q Sbjct: 581 ENGER-WGFAMLPRLVSNSWVQ 601 >gi|231571356 nitric oxide synthase 3 isoform 4 [Homo sapiens] Length = 629 Score = 57.4 bits (137), Expect = 3e-08 Identities = 29/62 (46%), Positives = 42/62 (67%), Gaps = 1/62 (1%) Query: 8 VLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCATTGQGDPP 67 +L+GS+TG AQ +++LGR R+ RV +D Y VV+L +E LV+ V +T G GDPP Sbjct: 522 ILYGSETGRAQSYAQQLGR-LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPP 580 Query: 68 DN 69 +N Sbjct: 581 EN 582 >gi|231571314 nitric oxide synthase 3 isoform 2 [Homo sapiens] Length = 596 Score = 57.4 bits (137), Expect = 3e-08 Identities = 29/62 (46%), Positives = 42/62 (67%), Gaps = 1/62 (1%) Query: 8 VLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCATTGQGDPP 67 +L+GS+TG AQ +++LGR R+ RV +D Y VV+L +E LV+ V +T G GDPP Sbjct: 522 ILYGSETGRAQSYAQQLGR-LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPP 580 Query: 68 DN 69 +N Sbjct: 581 EN 582 >gi|50726981 radical S-adenosyl methionine and flavodoxin domains 1 [Homo sapiens] Length = 732 Score = 47.0 bits (110), Expect = 4e-05 Identities = 41/134 (30%), Positives = 65/134 (48%), Gaps = 10/134 (7%) Query: 8 VLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSY-PVVNLINEP----LVIFVCATTG 62 + +GSQTGTA+ + L L + L Y P +LI E + +F+ AT Sbjct: 81 IFYGSQTGTAKGFATVLAEAVTSLDLPVAIINLKEYDPDDHLIEEVTSKNVCVFLVATYT 140 Query: 63 QGDPPDNMKNFWRFIFRKNLP----STALCQMDFAVLGLGDSSYAK-FNFVAKKLHRRLL 117 G P ++ + F +++ ++ T L M +AV GLG+S+YA FN V K + + L Sbjct: 141 DGLPTESAEWFCKWLEEASIDFRFGKTYLKGMRYAVFGLGNSAYASHFNKVGKNVDKWLW 200 Query: 118 QLGGSALLPVCLGD 131 LG ++ GD Sbjct: 201 MLGAHRVMSRGEGD 214 >gi|224282123 tRNA-yW synthesizing protein 1 homolog B isoform 1 [Homo sapiens] Length = 668 Score = 35.0 bits (79), Expect = 0.17 Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 5/85 (5%) Query: 41 DSYPVVNLINEPLVIFVCATTGQGDPPDNMKNFWRFIFRKNLP----STALCQMDFAVLG 96 D + + + ++ + +F+ AT G P ++ + F +++ ++ T L M AV G Sbjct: 73 DDHLIEEVTSKNVCVFLVATYTDGLPTESAEWFCKWLEEASIDFRFGKTYLKGMRDAVFG 132 Query: 97 LGDSSYAK-FNFVAKKLHRRLLQLG 120 LG+S+YA FN V K + + L LG Sbjct: 133 LGNSAYASHFNKVGKNVDKWLWMLG 157 >gi|27312029 hypothetical protein LOC145376 [Homo sapiens] Length = 422 Score = 33.5 bits (75), Expect = 0.48 Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 5/81 (6%) Query: 1 MPSPQLLVLFGSQTGTAQDVSERLGREARRR---RLGCRVQALDSYP--VVNLINEPLVI 55 M SP + L S AQ+V E+ + R + V LDS P VV ++ EP + Sbjct: 312 MRSPVMSTLLPSLREKAQNVFEKKYHQVDVRFPAEMQKHVGTLDSVPMPVVGILGEPRCL 371 Query: 56 FVCATTGQGDPPDNMKNFWRF 76 F T DP +N K+F R+ Sbjct: 372 FNPHTLHPLDPEENTKSFGRY 392 >gi|145587088 hypothetical protein LOC165186 [Homo sapiens] Length = 1019 Score = 32.7 bits (73), Expect = 0.83 Identities = 18/35 (51%), Positives = 23/35 (65%), Gaps = 2/35 (5%) Query: 370 VQFQTRLKEPR--RGLCSSWLASLDPGQGPVRVPL 402 +Q + +LK+ R GL +S ASLDPG GP VPL Sbjct: 122 IQIKDKLKKRRLSEGLAASSRASLDPGGGPQGVPL 156 >gi|89242137 Meckel syndrome, type 1 [Homo sapiens] Length = 559 Score = 29.6 bits (65), Expect = 7.0 Identities = 17/58 (29%), Positives = 33/58 (56%), Gaps = 2/58 (3%) Query: 293 REKLLEFSSAQGQEE--LFEYCNRPRRTILEVLCDFPHTAAAIPPDYLLDLIPVIRPR 348 R+++L+ ++ G++ +F Y + R T LE C TAA+ P +L++ + +R R Sbjct: 108 RQEILKLENSGGKKNRRIFTYTDSDRYTNLEEHCQRMTTAASEVPSFLVERMANVRRR 165 >gi|223468693 hypothetical protein LOC100130361 [Homo sapiens] Length = 514 Score = 29.3 bits (64), Expect = 9.1 Identities = 19/51 (37%), Positives = 25/51 (49%), Gaps = 7/51 (13%) Query: 377 KEPRRGLCSSWLASLDPGQ----GPVRVPLWVRPGSLAFPETPDTPVIMVG 423 K P RG S W +DP Q GP R+P S + E+ D P++ VG Sbjct: 172 KNPERGSKSRWSLRVDPQQPSAKGPTRLP---THDSDSADESSDLPLMKVG 219 >gi|223468690 hypothetical protein LOC100132994 [Homo sapiens] Length = 514 Score = 29.3 bits (64), Expect = 9.1 Identities = 19/51 (37%), Positives = 25/51 (49%), Gaps = 7/51 (13%) Query: 377 KEPRRGLCSSWLASLDPGQ----GPVRVPLWVRPGSLAFPETPDTPVIMVG 423 K P RG S W +DP Q GP R+P S + E+ D P++ VG Sbjct: 172 KNPERGSKSRWSLRVDPQQPSAKGPTRLP---THDSDSADESSDLPLMKVG 219 >gi|124028529 symplekin [Homo sapiens] Length = 1274 Score = 29.3 bits (64), Expect = 9.1 Identities = 43/205 (20%), Positives = 76/205 (37%), Gaps = 29/205 (14%) Query: 206 ISFAAGDVVLIQPSNS---AAHVQRFCQVLGLDPDQLFMLQPREPDVSSPTRLPQPCSMR 262 +S AGD++L+ S++ H +F + L + L PR D P R Sbjct: 161 VSAMAGDIILLLDSDNDGIRTHAIKFVEGL------IVTLSPRMADSEIPRRQ------- 207 Query: 263 HLVSHYLDIASVPR-RSFFELLACLSLHELEREKLLEF------SSAQGQEELFEYCNRP 315 H + + +PR + + + E+LL+F SS L N Sbjct: 208 ---EHDISLDRIPRDHPYIQYNVLWEEGKAALEQLLKFMVHPAISSINLTTALGSLANIA 264 Query: 316 RRTIL---EVLCDFPHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQF 372 R+ + EV+ + A +PP + +R S+L HP+ L+ + Sbjct: 265 RQRPMFMSEVIQAYETLHANLPPTLAKSQVSSVRKNLKLHLLSVLKHPASLEFQAQITTL 324 Query: 373 QTRLKEPRRGLCSSWLASLDPGQGP 397 L P+ + + +S D + P Sbjct: 325 LVDLGTPQAEIARNMPSSKDTRKRP 349 >gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens] Length = 993 Score = 29.3 bits (64), Expect = 9.1 Identities = 15/38 (39%), Positives = 19/38 (50%) Query: 146 FLQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQ 183 FLQE G E R A P +PP+ P P ++NQ Sbjct: 76 FLQEGLEKGDEELRPALPFQPDPPAPFTPSPLPRLANQ 113 >gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens] Length = 994 Score = 29.3 bits (64), Expect = 9.1 Identities = 15/38 (39%), Positives = 19/38 (50%) Query: 146 FLQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQ 183 FLQE G E R A P +PP+ P P ++NQ Sbjct: 76 FLQEGLEKGDEELRPALPFQPDPPAPFTPSPLPRLANQ 113 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.323 0.139 0.429 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,094,264 Number of Sequences: 37866 Number of extensions: 1147056 Number of successful extensions: 2766 Number of sequences better than 10.0: 23 Number of HSP's better than 10.0 without gapping: 16 Number of HSP's successfully gapped in prelim test: 7 Number of HSP's that attempted gapping in prelim test: 2700 Number of HSP's gapped (non-prelim): 37 length of query: 521 length of database: 18,247,518 effective HSP length: 107 effective length of query: 414 effective length of database: 14,195,856 effective search space: 5877084384 effective search space used: 5877084384 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.