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Search of human proteins with 221316650
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221316650 ephrin receptor EphA1 [Homo sapiens]
(976 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221316650 ephrin receptor EphA1 [Homo sapiens] 2022 0.0
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 916 0.0
gi|4758282 ephrin receptor EphA7 [Homo sapiens] 808 0.0
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap... 798 0.0
gi|4758280 ephrin receptor EphA4 [Homo sapiens] 796 0.0
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap... 789 0.0
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi... 772 0.0
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] 745 0.0
gi|145312251 EPH receptor A6 isoform a [Homo sapiens] 743 0.0
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens] 738 0.0
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi... 726 0.0
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi... 723 0.0
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap... 722 0.0
gi|32528301 EPH receptor B4 precursor [Homo sapiens] 707 0.0
gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens] 701 0.0
gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens] 634 0.0
gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo sapi... 383 e-106
gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo sapi... 326 7e-89
gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens] 232 1e-60
gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens] 232 1e-60
gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens] 228 2e-59
gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens] 221 3e-57
gi|27597078 TYRO3 protein tyrosine kinase [Homo sapiens] 216 8e-56
gi|219842236 feline sarcoma oncogene isoform 4 [Homo sapiens] 215 1e-55
gi|219842233 feline sarcoma oncogene isoform 3 [Homo sapiens] 215 1e-55
gi|219842230 feline sarcoma oncogene isoform 2 [Homo sapiens] 215 1e-55
gi|4503687 feline sarcoma oncogene isoform 1 [Homo sapiens] 215 1e-55
gi|66932918 MER receptor tyrosine kinase precursor [Homo sapiens] 214 2e-55
gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens] 213 9e-55
gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens] 213 9e-55
>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
Length = 976
Score = 2022 bits (5239), Expect = 0.0
Identities = 976/976 (100%), Positives = 976/976 (100%)
Query: 1 MERRWPLGLGLVLLLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQILNG 60
MERRWPLGLGLVLLLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQILNG
Sbjct: 1 MERRWPLGLGLVLLLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQILNG 60
Query: 61 TPLYMYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKE 120
TPLYMYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKE
Sbjct: 61 TPLYMYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKE 120
Query: 121 TFNLLYMESDQDVGIQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRG 180
TFNLLYMESDQDVGIQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRG
Sbjct: 121 TFNLLYMESDQDVGIQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRG 180
Query: 181 LYLAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGPAGLVEVAGTCLPHARASPR 240
LYLAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGPAGLVEVAGTCLPHARASPR
Sbjct: 181 LYLAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGPAGLVEVAGTCLPHARASPR 240
Query: 241 PSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQ 300
PSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQ
Sbjct: 241 PSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQ 300
Query: 301 STAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGG 360
STAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGG
Sbjct: 301 STAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGG 360
Query: 361 RQDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVE 420
RQDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVE
Sbjct: 361 RQDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVE 420
Query: 421 AQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSPGANLT 480
AQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSPGANLT
Sbjct: 421 AQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSPGANLT 480
Query: 481 YELHVLNQDEERYQMVLEPRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPPVS 540
YELHVLNQDEERYQMVLEPRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPPVS
Sbjct: 481 YELHVLNQDEERYQMVLEPRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPPVS 540
Query: 541 RGLTGGEIVAVIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRATDVDREDKLWLKPYV 600
RGLTGGEIVAVIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRATDVDREDKLWLKPYV
Sbjct: 541 RGLTGGEIVAVIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRATDVDREDKLWLKPYV 600
Query: 601 DLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKD 660
DLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKD
Sbjct: 601 DLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKD 660
Query: 661 TSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQ 720
TSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQ
Sbjct: 661 TSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQ 720
Query: 721 LVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGT 780
LVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGT
Sbjct: 721 LVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGT 780
Query: 781 YETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIE 840
YETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIE
Sbjct: 781 YETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIE 840
Query: 841 DGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLRTIANFDPRM 900
DGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLRTIANFDPRM
Sbjct: 841 DGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLRTIANFDPRM 900
Query: 901 TLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLELTAEDLTQMGITL 960
TLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLELTAEDLTQMGITL
Sbjct: 901 TLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLELTAEDLTQMGITL 960
Query: 961 PGHQKRILCSIQGFKD 976
PGHQKRILCSIQGFKD
Sbjct: 961 PGHQKRILCSIQGFKD 976
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 916 bits (2368), Expect = 0.0
Identities = 488/964 (50%), Positives = 634/964 (65%), Gaps = 30/964 (3%)
Query: 23 ARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQILNGTPLYMYQDCPMQGRRDTDHWLR 82
A+ KEV L+D + A GELGWL P GW Q I+N P+YMY C + D D+WLR
Sbjct: 24 AQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDMPIYMYSVCNVMSG-DQDNWLR 82
Query: 83 SNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYMESDQDVGIQLRRPLF 142
+NW+YRGE A R+ +EL+FTVRDC SFPGGA CKETFNL Y ESD D G ++ LF
Sbjct: 83 TNWVYRGE-AERIFIELKFTVRDCNSFPGGAS--SCKETFNLYYAESDLDYGTNFQKRLF 139
Query: 143 QKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLAFHNPGACVALVSVRVFYQ 202
K+ T+A D+ D + VKLNVE S+G LTR+G YLAF + GACVAL+SVRV+Y+
Sbjct: 140 TKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVALLSVRVYYK 199
Query: 203 RCPETLNGLAQFPDTLPGP--AGLVEVAGTCLPHARASPRPSGAPRMHCSPDGEWLVPVG 260
+CPE L GLA FP+T+ G L VAGTC+ HA P PRMHC+ DGEWLVP+G
Sbjct: 200 KCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGE-EPRMHCAVDGEWLVPIG 258
Query: 261 RCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTAESEGATICTCESGHYRA 320
+C C+ GYE+ +AC AC G ++ + CL CP+ + EGAT C CE G +RA
Sbjct: 259 QCLCQAGYEK--VEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSCECEEGFFRA 316
Query: 321 PGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGRQDVRYSVRCSQCQGTAQDG 380
P + + CT PPSAP L+ G ++ LRW PP D+GGR+D+ YSV C QC +
Sbjct: 317 PQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCEQCW---PES 373
Query: 381 GPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQNGVSGLGSSGHASTSVSI 440
G C PC V +S GLT +V V+ LEP+ NYTF VEA+NGVSGL +S T+ S+
Sbjct: 374 GECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTSRSFRTA-SV 432
Query: 441 SMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSPGANLTYELHVLNQDEERYQMVLEPR 500
S+ E +RL + L ++W+ P+ YE+ + + V
Sbjct: 433 SINQTEPPK---VRLEGRSTTSLSVSWSIPPPQQSRV-WKYEVTYRKKGDSNSYNVRRTE 488
Query: 501 ---VLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPPVSRGLTGGEIVAVIFGLLL 557
V L +L PDTTY+V+V+ LT G G S HEF+T P G +AVI G+ +
Sbjct: 489 GFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGN-----LAVIGGVAV 543
Query: 558 GAALLL---GILVFRSRRAQRQRQQRQRDRATDVDREDKLWLKPYVDLQAYEDPAQGALD 614
G LLL G+ F RR + QR ++ + E LK YVD YEDP Q L
Sbjct: 544 GVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQAVLK 603
Query: 615 FTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKT-VAIKTLKDTSPGGQWWNFLRE 673
FT E+ P+ + VIG GEFGEVY+G L+ S + VAIKTLK Q +FL E
Sbjct: 604 FTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGE 663
Query: 674 ATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQGI 733
A IMGQFSH +I+ LEGV++K KP+MIITE+MENGALD FLRE++ + QLV ML+GI
Sbjct: 664 AGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGI 723
Query: 734 ASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLL-DDFDGTYETQGGKIPIRW 792
A+GM YL+N NYVHRDLAARNILVN NL CKVSDFGL+R+L DD + TY T GGKIPIRW
Sbjct: 724 AAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRW 783
Query: 793 TAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCP 852
TAPEAI++R FT+ASDVWSFGIVMWEV+++G++PY E+SN EVMK+I DG+RLP P+DCP
Sbjct: 784 TAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCP 843
Query: 853 APLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLRTIANFDPRMTLRLPSLSGSDG 912
+ +Y+LM CW +RARRP F + + L++L+ P SL+T+A+FDPR+++RLPS SGS+G
Sbjct: 844 SAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLPSTSGSEG 903
Query: 913 IPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLELTAEDLTQMGITLPGHQKRILCSIQ 972
+P+RTVSEWLESI+M++Y HF +AG +E V+++T +D+ ++G+ LPGHQKRI S+
Sbjct: 904 VPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLPGHQKRIAYSLL 963
Query: 973 GFKD 976
G KD
Sbjct: 964 GLKD 967
>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
Length = 998
Score = 808 bits (2087), Expect = 0.0
Identities = 445/993 (44%), Positives = 617/993 (62%), Gaps = 45/993 (4%)
Query: 5 WPLGLGLVLLLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LNGTPL 63
W + + LL A AKEV L+D+ Q EL W+ PP +GW E + N TP+
Sbjct: 10 WIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPP-NGWEEISGLDENYTPI 68
Query: 64 YMYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFN 123
YQ C + + ++WLR+NWI +G A R+ VEL+FT+RDC S PG G CKETFN
Sbjct: 69 RTYQVCQVM-EPNQNNWLRTNWISKGN-AQRIFVELKFTLRDCNSLPGVLGT--CKETFN 124
Query: 124 LLYMESDQDVGIQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYL 183
L Y E+D D G +R L+ K+ T+AAD+SFT DL +KLN E +G L+++G YL
Sbjct: 125 LYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYL 184
Query: 184 AFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGP--AGLVEVAGTCLPHARASPRP 241
AF + GAC+ALVSV+V+Y++C + LA FPDT+ G + LVEV GTC+ + A
Sbjct: 185 AFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCV--SSAEEEA 242
Query: 242 SGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQS 301
APRMHCS +GEWLVP+G+C C+ GY++ G+ C C G Y+ C CP S
Sbjct: 243 ENAPRMHCSAEGEWLVPIGKCICKAGYQQ--KGDTCEPCGRGFYKSSSQDLQCSRCPTHS 300
Query: 302 TAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGR 361
++ EG++ C CE G+YRAP + P VACT PPSAP+NL F+ + T +SL W PPAD GGR
Sbjct: 301 FSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGR 360
Query: 362 QDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEA 421
DV Y + C +C + + G C PCG + + P GL V V L +ANYTF VEA
Sbjct: 361 NDVTYRILCKRC---SWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEA 417
Query: 422 QNGVSGLGSSGHASTSVSISMGHA--ESLSGLSLRLVKKEPRQLELTWAGSRPRSPGANL 479
NGVS L S +VSI+ G A +SG+ V + R +EL+W P P +
Sbjct: 418 VNGVSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQ--RSVELSW--QEPEHPNGVI 473
Query: 480 T-YELHVLNQDE-ERYQMVLEPR---VLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFR 534
T YE+ +D+ ER ++ + + L+P T Y+ ++R T G G +SP +
Sbjct: 474 TEYEIKYYEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVA 533
Query: 535 TSPPVSRGLTGGEIVA-------VIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRATD 587
T + + V+ +I + + ++L +VF +R + D+ D
Sbjct: 534 TLEEATGKMFEATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGD 593
Query: 588 VDREDKLWL-------KPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYR 640
++L+ K Y+D + YEDP + F +ELD + + ++ VIG GEFGEV
Sbjct: 594 ----EELYFHFKFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCS 649
Query: 641 GTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMI 700
G L+LP + VAIKTLK Q +FL EA+IMGQF HP+++HLEGVVT+ KP+MI
Sbjct: 650 GRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMI 709
Query: 701 ITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQN 760
+ EFMENGALDAFLR+ + Q QLV ML+GIA+GM YL++ YVHRDLAARNILVN N
Sbjct: 710 VIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSN 769
Query: 761 LCCKVSDFGLTRLL-DDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEV 819
L CKVSDFGL+R++ DD + Y T GGKIP+RWTAPEAI +R FT+ASDVWS+GIVMWEV
Sbjct: 770 LVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEV 829
Query: 820 LSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAH 879
+S+G++PY +MSNQ+V+K+IE+GYRLP P+DCPA L++LM +CW +RA RP F+++
Sbjct: 830 MSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGI 889
Query: 880 LEQLLANPHSLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGL 939
L++++ NP+SL+T R L + D + +V EWL++I+M+RY +F +AG
Sbjct: 890 LDKMIRNPNSLKTPLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGY 949
Query: 940 DTMECVLELTAEDLTQMGITLPGHQKRILCSIQ 972
+++E V +T ED+ +GITL GHQK+I+ SIQ
Sbjct: 950 NSLESVARMTIEDVMSLGITLVGHQKKIMSSIQ 982
>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens]
Length = 1015
Score = 798 bits (2060), Expect = 0.0
Identities = 433/987 (43%), Positives = 610/987 (61%), Gaps = 31/987 (3%)
Query: 3 RRWPLGLGLVLLLCAPLPP--GARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LN 59
RR PL LLLCA L + + EV L+D+ G+LGW+ P K+GW E ++ N
Sbjct: 36 RRAPLWT--CLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFP-KNGWEEIGEVDEN 92
Query: 60 GTPLYMYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCK 119
P++ YQ C + ++ ++WL ++WI E ASR+ +EL+FT+RDC S PGG G CK
Sbjct: 93 YAPIHTYQVCKVM-EQNQNNWLLTSWI-SNEGASRIFIELKFTLRDCNSLPGGLGT--CK 148
Query: 120 ETFNLLYMESDQDVGIQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRR 179
ETFN+ Y ESD G ++ + K+ T+AAD+SFT DL +KLN E +G L+++
Sbjct: 149 ETFNMYYFESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKK 208
Query: 180 GLYLAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGP--AGLVEVAGTCLPHARA 237
G YLAF + GAC+ALVSVRV+Y++CP + LA FPDT+ G + L+EV+G+C+ H+
Sbjct: 209 GFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHS-V 267
Query: 238 SPRPSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTC 297
+ P P+MHCS +GEWLVP+G+C C+ GYEE C C G ++ C C
Sbjct: 268 TDEP---PKMHCSAEGEWLVPIGKCMCKAGYEEKNG--TCQVCRPGFFKASPHIQSCGKC 322
Query: 298 PQQSTAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPAD 357
P S E +T C CE ++R + P +ACT PPSAPRN + + T + L W PPAD
Sbjct: 323 PPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPAD 382
Query: 358 TGGRQDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTF 417
TGGR+DV Y + C +C A G C+ CG V + P GL +V + L + NYTF
Sbjct: 383 TGGRKDVSYYIACKKCNSHA---GVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTF 439
Query: 418 NVEAQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSPGA 477
+EA NGVS L SV+++ A +++ K + L+W R G
Sbjct: 440 EIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQ-EPDRPNGI 498
Query: 478 NLTYELHVLNQDEERYQMVL---EPRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFR 534
L YE+ +D+E ++ E + L+P + Y+ ++R T G G FS EF
Sbjct: 499 ILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFE 558
Query: 535 TSPPVSRGLTGGEIVAVIFGLLLGAALL---LGILVFRSRRA-QRQRQQRQRDRATDVDR 590
T+P + +I + + +G LL +G+L+ R + +Q + ++ +
Sbjct: 559 TTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGRRCGYSKAKQDPEEEKMHFHNG 618
Query: 591 EDKL-WLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQD 649
KL ++ Y+D YEDP Q +F +E++ + + ++ VIG GEFGEV G L+LP +
Sbjct: 619 HIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKR 678
Query: 650 CKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGA 709
VAIKTLK Q +FL EA+IMGQF HP+I+HLEGVVTK KP+MI+TE+MENG+
Sbjct: 679 ELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGS 738
Query: 710 LDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFG 769
LD FL++ + Q QLV ML+GI++GM YLS+ YVHRDLAARNIL+N NL CKVSDFG
Sbjct: 739 LDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFG 798
Query: 770 LTRLL-DDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYG 828
L+R+L DD + Y T+GGKIPIRWTAPEAIA R FT+ASDVWS+GIVMWEV+S+G++PY
Sbjct: 799 LSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYW 858
Query: 829 EMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPH 888
EM+NQ+V+K++E+GYRLP P+DCPA LY+LM +CW +R RP F ++ L++L+ NP
Sbjct: 859 EMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPS 918
Query: 889 SLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLEL 948
SL+T+ N R++ L S YR+V EWLE+I+M RY F G +M+ V ++
Sbjct: 919 SLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQV 978
Query: 949 TAEDLTQMGITLPGHQKRILCSIQGFK 975
T EDL ++G+TL GHQK+I+ S+Q K
Sbjct: 979 TLEDLRRLGVTLVGHQKKIMNSLQEMK 1005
>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
Length = 986
Score = 796 bits (2057), Expect = 0.0
Identities = 439/962 (45%), Positives = 606/962 (62%), Gaps = 27/962 (2%)
Query: 25 AKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQILN--GTPLYMYQDCPMQGRRDTDHWLR 82
A EVTL+D+ QGELGW+ P + GW E+ I++ TP+ YQ C + ++WLR
Sbjct: 28 ANEVTLLDSRSVQGELGWIASPLEGGW-EEVSIMDEKNTPIRTYQVCNVM-EPSQNNWLR 85
Query: 83 SNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYMESDQDVGIQLRRPLF 142
++WI R E A RV++E++FT+RDC S PG G CKETFNL Y ESD D +R F
Sbjct: 86 TDWITR-EGAQRVYIEIKFTLRDCNSLPGVMGT--CKETFNLYYYESDNDKERFIRENQF 142
Query: 143 QKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLAFHNPGACVALVSVRVFYQ 202
K+ T+AAD+SFT D+ +KLN E +G L+++G YLAF + GAC+ALVSVRVFY+
Sbjct: 143 VKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYK 202
Query: 203 RCPETLNGLAQFPDTLPGP--AGLVEVAGTCLPHARASPRPSGAPRMHCSPDGEWLVPVG 260
+CP T+ LAQFPDT+ G + LVEV G+C+ ++ P+M+C DGEWLVP+G
Sbjct: 203 KCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKD----VPKMYCGADGEWLVPIG 258
Query: 261 RCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTAESEGATICTCESGHYRA 320
C C G+EE SGE C AC G Y+ C CP S + EGAT CTC+ G +RA
Sbjct: 259 NCLCNAGHEER-SGE-CQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRA 316
Query: 321 PGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGRQDVRYSVRCSQCQGTAQDG 380
+ + CT PPSAP NL + + T ++L W P +TGGRQD+ Y+V C +C A D
Sbjct: 317 DNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCG--AGDP 374
Query: 381 GPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQNGVSGLGSSGHASTSVSI 440
C+PCG GVH++P GL T V + L + NYTF + A NGVS + S SV++
Sbjct: 375 SKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTV 434
Query: 441 SMGHAESLSGLSLRLVK-KEPRQLELTWAGSRPRSP-GANLTYELHVLNQDE-ERYQMVL 497
+ A + S+ LV+ KE + + A P P G L YE+ +D+ ER ++
Sbjct: 435 TTNQA---APSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIV 491
Query: 498 EPRVLLTE---LQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPPVSRGLTGGEIVAVIFG 554
T+ L P T+Y+ VR T G G FS E T+ SR + G V+
Sbjct: 492 RTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLV 551
Query: 555 LLLGAALLLGILVFRSRRAQRQRQQRQRDRATDVDREDKLWLKPYVDLQAYEDPAQGALD 614
+ G+ +L+ IL+ ++R+ + + + D ++ ++ YVD YEDP Q +
Sbjct: 552 SVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVRE 611
Query: 615 FTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREA 674
F +E+D + + ++ VIG GEFGEV G L++P + VAIKTLK Q +FL EA
Sbjct: 612 FAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEA 671
Query: 675 TIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIA 734
+IMGQF HP+I+HLEGVVTK KP+MIITE+MENG+LDAFLR+ + + QLV ML+GI
Sbjct: 672 SIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIG 731
Query: 735 SGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLL-DDFDGTYETQGGKIPIRWT 793
SGM YLS+ +YVHRDLAARNILVN NL CKVSDFG++R+L DD + Y T+GGKIPIRWT
Sbjct: 732 SGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWT 791
Query: 794 APEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPA 853
APEAIA+R FT+ASDVWS+GIVMWEV+S+G++PY +MSNQ+V+K+IE+GYRLPPP+DCP
Sbjct: 792 APEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPI 851
Query: 854 PLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLRTIANFDPRMTLRLPSLSGSDGI 913
L++LM +CW +R+ RP F ++ L++L+ NP+SL+ R L S +
Sbjct: 852 ALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPEFS 911
Query: 914 PYRTVSEWLESIRMKRYILHFHSAGLDTMECVLELTAEDLTQMGITLPGHQKRILCSIQG 973
+V +WL++I+M RY +F +AG T+E V+ + EDL ++GIT HQ +IL S+Q
Sbjct: 912 AVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQA 971
Query: 974 FK 975
+
Sbjct: 972 MR 973
>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens]
Length = 1037
Score = 789 bits (2037), Expect = 0.0
Identities = 435/1009 (43%), Positives = 612/1009 (60%), Gaps = 53/1009 (5%)
Query: 3 RRWPLGLGLVLLLCAPLPP--GARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LN 59
RR PL LLLCA L + + EV L+D+ G+LGW+ P K+GW E ++ N
Sbjct: 36 RRAPLWT--CLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFP-KNGWEEIGEVDEN 92
Query: 60 GTPLYMYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCK 119
P++ YQ C + ++ ++WL ++WI E ASR+ +EL+FT+RDC S PGG G CK
Sbjct: 93 YAPIHTYQVCKVM-EQNQNNWLLTSWI-SNEGASRIFIELKFTLRDCNSLPGGLGT--CK 148
Query: 120 ETFNLLYMESDQDVGIQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRR 179
ETFN+ Y ESD G ++ + K+ T+AAD+SFT DL +KLN E +G L+++
Sbjct: 149 ETFNMYYFESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKK 208
Query: 180 GLYLAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGP--AGLVEVAGTCLPHARA 237
G YLAF + GAC+ALVSVRV+Y++CP + LA FPDT+ G + L+EV+G+C+ H+
Sbjct: 209 GFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHS-V 267
Query: 238 SPRPSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTC 297
+ P P+MHCS +GEWLVP+G+C C+ GYEE C C G ++ C C
Sbjct: 268 TDEP---PKMHCSAEGEWLVPIGKCMCKAGYEEKNG--TCQVCRPGFFKASPHIQSCGKC 322
Query: 298 PQQSTAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPAD 357
P S E +T C CE ++R + P +ACT PPSAPRN + + T + L W PPAD
Sbjct: 323 PPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPAD 382
Query: 358 TGGRQDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTF 417
TGGR+DV Y + C +C A G C+ CG V + P GL +V + L + NYTF
Sbjct: 383 TGGRKDVSYYIACKKCNSHA---GVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTF 439
Query: 418 NVEAQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSPGA 477
+EA NGVS L SV+++ A +++ K + L+W R G
Sbjct: 440 EIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQ-EPDRPNGI 498
Query: 478 NLTYELHVLNQDEERYQMVL---EPRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFR 534
L YE+ +D+E ++ E + L+P + Y+ ++R T G G FS EF
Sbjct: 499 ILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFE 558
Query: 535 TSPPVSRGLTGGEIVAVIFGLLLGAALL---LGILVFRS------RRAQ----------- 574
T+P + +I + + +G LL +G+L+ S RA
Sbjct: 559 TTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLI 618
Query: 575 ------RQRQQRQRDRATDVDREDKL-WLKPYVDLQAYEDPAQGALDFTRELDPAWLMVD 627
+ +Q + ++ + KL ++ Y+D YEDP Q +F +E++ + + ++
Sbjct: 619 WRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIE 678
Query: 628 TVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILH 687
VIG GEFGEV G L+LP + VAIKTLK Q +FL EA+IMGQF HP+I+H
Sbjct: 679 RVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIH 738
Query: 688 LEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVH 747
LEGVVTK KP+MI+TE+MENG+LD FL++ + Q QLV ML+GI++GM YLS+ YVH
Sbjct: 739 LEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVH 798
Query: 748 RDLAARNILVNQNLCCKVSDFGLTRLL-DDFDGTYETQGGKIPIRWTAPEAIAHRIFTTA 806
RDLAARNIL+N NL CKVSDFGL+R+L DD + Y T+GGKIPIRWTAPEAIA R FT+A
Sbjct: 799 RDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSA 858
Query: 807 SDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYD 866
SDVWS+GIVMWEV+S+G++PY EM+NQ+V+K++E+GYRLP P+DCPA LY+LM +CW +
Sbjct: 859 SDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKE 918
Query: 867 RARRPHFQKLQAHLEQLLANPHSLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIR 926
R RP F ++ L++L+ NP SL+T+ N R++ L S YR+V EWLE+I+
Sbjct: 919 RNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIK 978
Query: 927 MKRYILHFHSAGLDTMECVLELTAEDLTQMGITLPGHQKRILCSIQGFK 975
M RY F G +M+ V ++T EDL ++G+TL GHQK+I+ S+Q K
Sbjct: 979 MGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMK 1027
>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo
sapiens]
Length = 983
Score = 772 bits (1993), Expect = 0.0
Identities = 427/983 (43%), Positives = 602/983 (61%), Gaps = 35/983 (3%)
Query: 11 LVLLLCAPLPPGAR-----AKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LNGTPLY 64
L+LL C+ L + EV L+D+ QGELGW+ P GW E + + TP+
Sbjct: 8 LLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWI-SYPSHGWEEISGVDEHYTPIR 66
Query: 65 MYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNL 124
YQ C + ++WLR+NW+ R A +++VEL+FT+RDC S P G CKETFNL
Sbjct: 67 TYQVCNVMDHSQ-NNWLRTNWVPRNS-AQKIYVELKFTLRDCNSIPLVLGT--CKETFNL 122
Query: 125 LYMESDQDVGIQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLA 184
YMESD D G++ R F K+ T+AAD+SFT DL +KLN E +G + ++G YLA
Sbjct: 123 YYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLA 182
Query: 185 FHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGPA-GLVEVAGTCLPHARASPRPSG 243
F + GACVALVSVRV++++CP T+ LA FPDT+P + LVEV G+C+ +++
Sbjct: 183 FQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEED---- 238
Query: 244 APRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTA 303
PRM+CS +GEWLVP+G+C C GYEE G C AC G Y+ C CP S+
Sbjct: 239 PPRMYCSTEGEWLVPIGKCSCNAGYEERGF--MCQACRPGFYKALDGNMKCAKCPPHSST 296
Query: 304 ESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGRQD 363
+ +G+ C CE+ ++RA + P +ACT PPS+PRN+ + + T + L W P DTGGR+D
Sbjct: 297 QEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKD 356
Query: 364 VRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQN 423
V +++ C +C + C+PC V F P GLT V V L + NYTF ++A N
Sbjct: 357 VTFNIICKKCGWNIKQ---CEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN 413
Query: 424 GVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSP-GANLTYE 482
GVS L S +VSI+ A L+++ + + L+W P P G L YE
Sbjct: 414 GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSW--QEPEHPNGIILDYE 471
Query: 483 L-HVLNQDEERYQMVLEPR---VLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPP 538
+ + Q++E +L R V ++ L+PDT Y+ ++R T G G S EF TSP
Sbjct: 472 VKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
Query: 539 VSRGLTGGEIVAVIFGLLLGAALLLGILVFRSRRAQ----RQRQQRQRDRATDVDREDKL 594
S ++G V+ + A++L +V + + + R + KL
Sbjct: 532 -SFSISGESSQVVMIAISAAVAIILLTVVIYVLIGRFCGYKSKHGADEKRLHFGNGHLKL 590
Query: 595 -WLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTV 653
L+ YVD YEDP Q +F +ELD + +D V+G GEFGEV G L+LPS+ +V
Sbjct: 591 PGLRTYVDPHTYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISV 650
Query: 654 AIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAF 713
AIKTLK Q +FL EA+IMGQF HP+I+ LEGVVTK KP+MI+TE+MENG+LD+F
Sbjct: 651 AIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSF 710
Query: 714 LREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRL 773
LR+ + Q QLV ML+GIASGM YLS+ YVHRDLAARNIL+N NL CKVSDFGL+R+
Sbjct: 711 LRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRV 770
Query: 774 L-DDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSN 832
L DD + Y T+GGKIPIRWT+PEAIA+R FT+ASDVWS+GIV+WEV+S+G++PY EMSN
Sbjct: 771 LEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSN 830
Query: 833 QEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLRT 892
Q+V+K++++GYRLPPP+DCPA LY+LM +CW DR RP F+++ + L++L+ NP SL+
Sbjct: 831 QDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKI 890
Query: 893 IANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLELTAED 952
I + R + L S D +RT +WL + F + + + +++ +D
Sbjct: 891 ITSAAARPSNLLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDD 950
Query: 953 LTQMGITLPGHQKRILCSIQGFK 975
+ ++G+T+ G QK+I+ SI+ +
Sbjct: 951 MKKVGVTVVGPQKKIISSIKALE 973
>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
Length = 998
Score = 745 bits (1924), Expect = 0.0
Identities = 429/987 (43%), Positives = 575/987 (58%), Gaps = 34/987 (3%)
Query: 6 PLGLGLVLLLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSE---QQQILNGTP 62
PL L+LL LP G RA E TLMDT EL W P+ GW E + +N P
Sbjct: 18 PLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWT-SHPESGWEEVSGYDEAMN--P 74
Query: 63 LYMYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETF 122
+ YQ C ++ ++WLR+ +I+R + RV+VEL+FTVRDC S P G CKETF
Sbjct: 75 IRTYQVCNVR-ESSQNNWLRTGFIWR-RDVQRVYVELKFTVRDCNSIPNIPG--SCKETF 130
Query: 123 NLLYMESDQDVG-----IQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLT 177
NL Y E+D DV + P + KV T+A D+SF+ D + ++N + S G L+
Sbjct: 131 NLFYYEADSDVASASSPFWMENP-YVKVDTIAPDESFSRLD----AGRVNTKVRSFGPLS 185
Query: 178 RRGLYLAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPG--PAGLVEVAGTCLPHA 235
+ G YLAF + GAC++L+SVR FY++C T G A FP+TL G P LV GTC+P+A
Sbjct: 186 KAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNA 245
Query: 236 RASPRPSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCL 295
P +++C+ DGEW+VPVG C C G+E C CP GSY+ CL
Sbjct: 246 VEVSVPL---KLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCL 302
Query: 296 TCPQQSTAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPP 355
CP S S A+ICTC + YRA + ACT PS PR + + + T L L W P
Sbjct: 303 PCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEP 362
Query: 356 ADTGGRQDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANY 415
D GGR D+ Y+V C +C G A C C V F P GLT VH++ L + Y
Sbjct: 363 RDLGGRDDLLYNVICKKCHG-AGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRY 421
Query: 416 TFNVEAQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSP 475
TF V+A NGVSG +V+I+ A +LRL L L+WA R
Sbjct: 422 TFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPE-RPN 480
Query: 476 GANLTYELHVLNQDEERYQMVLEPR--VLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEF 533
G L YE+ + E V V L L+PD Y+V+VR T G G +S EF
Sbjct: 481 GVILDYEMKYFEKSEGIASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEF 540
Query: 534 RTSPPVSRGLTG--GEIVAVIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRATDVDRE 591
T+ G ++ ++ G ++ ++V ++QR + + +
Sbjct: 541 ETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQY 600
Query: 592 DKLWLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCK 651
+K Y+D YEDP + +F +E+D + + ++ VIG GEFGEV RG L+ P +
Sbjct: 601 IAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREV 660
Query: 652 TVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALD 711
VAIKTLK Q +FL EA+IMGQF HP+I+ LEGVVTK +P+MI+TEFMEN ALD
Sbjct: 661 FVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALD 720
Query: 712 AFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLT 771
+FLR + Q QLV ML+GIA+GM YLS NYVHRDLAARNILVN NL CKVSDFGL+
Sbjct: 721 SFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLS 780
Query: 772 RLLDD--FDGTYETQ-GGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYG 828
R L+D D TY + GGKIPIRWTAPEAIA+R FT+ASDVWS+GIVMWEV+S+G++PY
Sbjct: 781 RFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYW 840
Query: 829 EMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPH 888
+MSNQ+V+ ++E YRLPPP+DCP L++LM +CW DR RP F ++ L++L+ N
Sbjct: 841 DMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAA 900
Query: 889 SLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLEL 948
SL+ IA+ M+ L + D + TV +WL++I+M RY F SAG + + V ++
Sbjct: 901 SLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQM 960
Query: 949 TAEDLTQMGITLPGHQKRILCSIQGFK 975
TAEDL ++G+TL GHQK+IL SIQ +
Sbjct: 961 TAEDLLRIGVTLAGHQKKILSSIQDMR 987
>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
Length = 1130
Score = 743 bits (1919), Expect = 0.0
Identities = 423/1009 (41%), Positives = 596/1009 (59%), Gaps = 85/1009 (8%)
Query: 27 EVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LNGTPLYMYQDCPMQGRRDTDHWLRSNW 85
+V L+DT+ GELGW P +GW ++ + P++ YQ C + + ++WLR+NW
Sbjct: 128 QVVLLDTTTVLGELGWKTYP-LNGWDAITEMDEHNRPIHTYQVCNVM-EPNQNNWLRTNW 185
Query: 86 IYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYMESDQDVGIQLRRPLFQKV 145
I R + A +++VE++FT+RDC S P G CKETFNL YMESD+ GI+ + + K+
Sbjct: 186 ISR-DAAQKIYVEMKFTLRDCNSIPWVLGT--CKETFNLFYMESDESHGIKFKPNQYTKI 242
Query: 146 TTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLAFHNPGACVALVSVRVFYQRCP 205
T+AAD+SFT DL +KLN E +G + R+G YLAF + GAC+ALVSVRVFY++CP
Sbjct: 243 DTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCP 302
Query: 206 ETLNGLAQFPDTLP--GPAGLVEVAGTCLPHARASPRPSGAPRMHCSPDGEWLVPVGRCH 263
T+ LA FPDT+P + LVEV G+C+ S P+++C DG+WLVP+GRC
Sbjct: 303 FTVRNLAMFPDTIPRVDSSSLVEVRGSCV----KSAEERDTPKLYCGADGDWLVPLGRCI 358
Query: 264 CEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTAESEGATICTCESGHYRAPGE 323
C GYEE +C AC G Y+ C CP S E ++C CE G++RA +
Sbjct: 359 CSTGYEE--IEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKD 416
Query: 324 GPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGRQDVRYSVRCSQCQGTAQDGGPC 383
P +ACT PPSAPRN+ F+ + T L L W PP+DTGGR+D+ YSV C +C D C
Sbjct: 417 PPSMACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKC---GLDTSQC 473
Query: 384 QPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQNGVSGLGSSGHASTSVSISMG 443
+ CG G+ F P GL +V V + NYTF +EA NGVS L S T+++++
Sbjct: 474 EDCGGGLRFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTD 533
Query: 444 H-AESLSGLSLRLVKKEPRQLELTWAGSRPRSPGANLTYELHVLNQDEER--YQMVLE-- 498
A SL G+ +R + L+W + S GA L YE+ ++ E+ Y
Sbjct: 534 QDAPSLIGV-VRKDWASQNSIALSWQ-APAFSNGAILDYEIKYYEKEHEQLTYSSTRSKA 591
Query: 499 PRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPPVS-RGLTGGEIVAVIFGLLL 557
P V++T L+P T Y+ +R+ T G +S EF T S G+I+ + +
Sbjct: 592 PSVIITGLKPATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVG 651
Query: 558 GAALLLGILVF-----RSRRAQRQRQQRQRDRATDVDREDKLW--LKPYVDLQAYEDPAQ 610
G LL+ + +F R + + + + + R + + +K Y+D YEDP+
Sbjct: 652 GFTLLVILTLFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSL 711
Query: 611 GALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNF 670
+F +E+DP+ + ++ VIG GEFGEV G L+ P + VAIKTLK Q +F
Sbjct: 712 AVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDF 771
Query: 671 LREATIMGQFSHPHILHLEGVVTKR----------------------------------- 695
LREA+IMGQF HP+I+ LEGVVTKR
Sbjct: 772 LREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSL 831
Query: 696 -------KPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHR 748
+P+MI+ E+MENG+LD+FLR+ + QLV ML+GIASGM YLS+ YVHR
Sbjct: 832 PPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHR 891
Query: 749 DLAARNILVNQNLCCKVSDFGLTRLL-DDFDGTYETQGGKIPIRWTAPEAIAHRIFTTAS 807
DLAARNILVN NL CKVSDFGL+R+L DD + Y T GGKIPIRWTAPEAIA+R F++AS
Sbjct: 892 DLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSAS 951
Query: 808 DVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDR 867
D WS+GIVMWEV+S+G++PY EMSNQ+V+ SIE+GYRLP P+ CPA L++LM +CW +R
Sbjct: 952 DAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKER 1011
Query: 868 ARRPHFQKLQAHLEQLLANPHSLRTIANFDPRMTLRLPSLSGSDGIP----YRTVSEWLE 923
RP F + + L++L+ NP +L T+ L +P G +P + TV +WL+
Sbjct: 1012 NHRPKFTDIVSFLDKLIRNPSALHTLV----EDILVMPESPGE--VPEYPLFVTVGDWLD 1065
Query: 924 SIRMKRYILHFHSAGLDTMECVLELTAEDLTQMGITLPGHQKRILCSIQ 972
SI+M +Y +F +AG T + + ++ +D+ ++G+ L GHQ+RI+ SIQ
Sbjct: 1066 SIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQ 1114
>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
Length = 984
Score = 738 bits (1904), Expect = 0.0
Identities = 423/991 (42%), Positives = 585/991 (59%), Gaps = 42/991 (4%)
Query: 9 LGLVLLLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LNGTPLYMYQ 67
+ L LL L A E TLMDT A ELGW +P GW E N + YQ
Sbjct: 1 MALDYLLLLLLASAVAAMEETLMDTRTATAELGWTANPAS-GWEEVSGYDENLNTIRTYQ 59
Query: 68 DCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYM 127
C + + ++WL + +I R A R++ E++FTVRDC S P G CKETFNL Y
Sbjct: 60 VCNVF-EPNQNNWLLTTFINR-RGAHRIYTEMRFTVRDCSSLPNVPG--SCKETFNLYYY 115
Query: 128 ESDQDVGIQLR----RPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYL 183
E+D + + + KV T+AAD+SF+ D +K+N E S G LTR G YL
Sbjct: 116 ETDSVIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYL 175
Query: 184 AFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGP--AGLVEVAGTCLPHARASPRP 241
AF + GAC++L+SVRVF+++CP + A FP+T+ G LV GTC+P+A P
Sbjct: 176 AFQDYGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVP 235
Query: 242 SGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQS 301
+++C+ DGEW+VP+GRC C+PGYE S AC ACP+G+++ + C CP S
Sbjct: 236 I---KLYCNGDGEWMVPIGRCTCKPGYEPENS-VACKACPAGTFKASQEAEGCSHCPSNS 291
Query: 302 TAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGR 361
+ +E + ICTC +G+YRA + P+VACT PS PRN+ + T + L W PP +TGGR
Sbjct: 292 RSPAEASPICTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGR 351
Query: 362 QDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEA 421
DV Y++ C +C+ D C C V F P GLT V ++ L + YTF+++A
Sbjct: 352 DDVTYNIICKKCRA---DRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQA 408
Query: 422 QNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSP-GANLT 480
NGVS SV+I+ A + + V R + L+W +P P G L
Sbjct: 409 INGVSSKSPFPPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWP--QPEQPNGIILD 466
Query: 481 YELHVLNQDEERYQMVLEPRVLLTE----LQPDTTYIVRVRMLTPLGPGPFS-------- 528
YE+ ++ + + T L+P Y+V+VR T G G FS
Sbjct: 467 YEIRYYEKEHNEFNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTL 526
Query: 529 PDHEFRTSPPVSRGLTGGEIVA-VIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRATD 587
D ++++ L G A V+F + L A + I+ R R ++ + +
Sbjct: 527 TDDDYKSELREQLPLIAGSAAAGVVFVVSLVA---ISIVCSRKRAYSKEAVYSDKLQHYS 583
Query: 588 VDREDKLWLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPS 647
R +K Y+D YEDP + +F +E+D +++ ++ VIG GEFGEVY+G L+LP
Sbjct: 584 TGRGSP-GMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPG 642
Query: 648 QDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMEN 707
+ VAIKTLK Q +FL EA+IMGQF HP+I+ LEGVVTK +P+MIITEFMEN
Sbjct: 643 KREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMEN 702
Query: 708 GALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSD 767
GALD+FLR+ + Q QLV ML+GIA+GM YL+ NYVHRDLAARNILVN NL CKVSD
Sbjct: 703 GALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSD 762
Query: 768 FGLTRLLDD--FDGTYETQ-GGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGD 824
FGL+R L D D TY + GGKIP+RWTAPEAIA+R FT+ASDVWS+GIVMWEV+SFG+
Sbjct: 763 FGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGE 822
Query: 825 KPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLL 884
+PY +MSNQ+V+ +IE YRLPPP+DCPA L++LM +CW DR RP F ++ L++++
Sbjct: 823 RPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMI 882
Query: 885 ANPHSLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMEC 944
NP SL+T+A + L S D + TV +WL +I+M +Y F +AG +++
Sbjct: 883 RNPASLKTVATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQL 942
Query: 945 VLELTAEDLTQMGITLPGHQKRILCSIQGFK 975
V ++T+EDL ++GITL GHQK+IL SI +
Sbjct: 943 VTQMTSEDLLRIGITLAGHQKKILNSIHSMR 973
>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo
sapiens]
Length = 1005
Score = 726 bits (1875), Expect = 0.0
Identities = 411/983 (41%), Positives = 572/983 (58%), Gaps = 61/983 (6%)
Query: 27 EVTLMDTSKAQGELGWLLDPPKDGWSEQQQILNG-TPLYMYQDCPMQGRRDTDHWLRSNW 85
EV L+DTS G+ GWL P GW ++ P++ YQ C + ++WLR++W
Sbjct: 31 EVNLLDTSTIHGDWGWLTYPAH-GWDSINEVDESFQPIHTYQVCNVMSPNQ-NNWLRTSW 88
Query: 86 IYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYMESDQDVGIQLRRPLFQKV 145
+ R + A RV+ E++FT+RDC S PG G CKETFNL Y+ESD+D+G + F K+
Sbjct: 89 VPR-DGARRVYAEIKFTLRDCNSMPGVLGT--CKETFNLYYLESDRDLGASTQESQFLKI 145
Query: 146 TTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLAFHNPGACVALVSVRVFYQRCP 205
T+AAD+SFT DL +KLN E S+G L++RG YLAF + GAC+A++S+R++Y++CP
Sbjct: 146 DTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCP 205
Query: 206 ETLNGLAQFPDTLPG--PAGLVEVAGTCLPHARASPRPSGAPRMHCSPDGEWLVPVGRCH 263
+ LA F + + G + LVEV G C+ H+ P+M+CS +GEWLVP+G+C
Sbjct: 206 AMVRNLAAFSEAVTGADSSSLVEVRGQCVRHS----EERDTPKMYCSAEGEWLVPIGKCV 261
Query: 264 CEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTAESEGATICTCESGHYRAPGE 323
C GYEE +ACVAC G Y+ C CP S + + A C C+ +YRA +
Sbjct: 262 CSAGYEE--RRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALD 319
Query: 324 GPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGRQDVRYSVRCSQCQGTAQDGGPC 383
P ACT PPSAP NL S +GT ++L W PP D GGR D+ Y+ C +C C
Sbjct: 320 PPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWAL---SRC 376
Query: 384 QPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQNGVSGLGSSGHASTSVSISMG 443
+ CG G F P L ++ V L + NY+F +EA NGVS L + V+I+
Sbjct: 377 EACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTN 436
Query: 444 HAESLSGLSLRLVKKEPRQLELTWAGSRPRSP-GANLTYELHVLNQDEERYQ----MVLE 498
A + +R + + L W P P G L YE+ +D+E +
Sbjct: 437 QAAPSQVVVIRQERAGQTSVSLLW--QEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVT 494
Query: 499 PRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPPVSRGLTGGEIVAVIFGLLLG 558
R ++ L+P T Y+ +VR T G G FS E T P R T IV + L+ G
Sbjct: 495 TRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDT-RTIVWICLTLITG 553
Query: 559 AALLLGILVFRSRRAQRQRQQRQRDRATDVDREDKLWLKP-------------------- 598
+LL +L+ + R + + D E+K+ +
Sbjct: 554 LVVLLLLLICKKRHCGYSKAFQDSD-------EEKMHYQNGQAPPPVFLPLHHPPGKLPE 606
Query: 599 ---YVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAI 655
Y + YE+P + FTRE++ + + ++ +IG G+ GEV G LR+P Q VAI
Sbjct: 607 PQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAI 666
Query: 656 KTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLR 715
K LK Q +FL EA+IMGQF HP+I+ LEGVVT+ + MI+TE+MENG+LD FLR
Sbjct: 667 KALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLR 726
Query: 716 EREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLL- 774
+ Q QLV ML+G+ +GM YLS+ YVHRDLAARN+LV+ NL CKVSDFGL+R+L
Sbjct: 727 THDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLE 786
Query: 775 DDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQE 834
DD D Y T GGKIPIRWTAPEAIA R F++ASDVWSFG+VMWEVL++G++PY M+N++
Sbjct: 787 DDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRD 846
Query: 835 VMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLR--- 891
V+ S+E+GYRLP P+ CP L++LM +CW DRA+RP F ++ + L+ L+ +P SLR
Sbjct: 847 VISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATA 906
Query: 892 TIANFDPRMTLR--LPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLELT 949
T++ P +R GS G TV +WL+SIRM RY HF + G ++ VL +
Sbjct: 907 TVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMN 966
Query: 950 AEDLTQMGITLPGHQKRILCSIQ 972
A+D+ +GITL GHQK+IL SIQ
Sbjct: 967 AQDVRALGITLMGHQKKILGSIQ 989
>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
sapiens]
Length = 987
Score = 723 bits (1866), Expect = 0.0
Identities = 415/986 (42%), Positives = 583/986 (59%), Gaps = 40/986 (4%)
Query: 9 LGLVLLLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LNGTPLYMYQ 67
LG LLL P A E TLMD++ A ELGW++ PP GW E N + YQ
Sbjct: 6 LGAALLLL----PLLAAVEETLMDSTTATAELGWMVHPPS-GWEEVSGYDENMNTIRTYQ 60
Query: 68 DCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYM 127
C + ++WLR+ +I R A R+HVE++F+VRDC S P G CKETFNL Y
Sbjct: 61 VCNVF-ESSQNNWLRTKFIRR-RGAHRIHVEMKFSVRDCSSIPSVPG--SCKETFNLYYY 116
Query: 128 ESDQDVGIQ-----LRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLY 182
E+D D + + P + KV T+AAD+SF+ DL +K+N E S G ++R G Y
Sbjct: 117 EADFDSATKTFPNWMENP-WVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFY 175
Query: 183 LAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGP--AGLVEVAGTCLPHARASPR 240
LAF + G C++L++VRVFY++CP + A F +TL G LV G+C+ +A
Sbjct: 176 LAFQDYGGCMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDV 235
Query: 241 PSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQ 300
P +++C+ DGEWLVP+GRC C+ G+E +G C CPSG+++ + C CP
Sbjct: 236 PI---KLYCNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPIN 292
Query: 301 STAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGG 360
S SEGAT C C +G+YRA + + CT PSAP+ + S + T L L W PP D+GG
Sbjct: 293 SRTTSEGATNCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGG 352
Query: 361 RQDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVE 420
R+D+ Y++ C C G C CG V ++P GLT P ++++ L + YTF ++
Sbjct: 353 REDLVYNIICKSC---GSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQ 409
Query: 421 AQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSP-GANL 479
A NGV+ SV+I+ A + + V + + L+W S+P P G L
Sbjct: 410 AVNGVTDQSPFSPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSW--SQPDQPNGVIL 467
Query: 480 TYELHVLNQDEERYQM--VLEPR--VLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRT 535
YEL ++ Y + P V + L+ Y+ +VR T G G +S F+T
Sbjct: 468 DYELQYYEKELSEYNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQT 527
Query: 536 SPPVSRGLTGGEIVAVIFGL-LLGAALLLGILVFRSRRAQRQRQQRQRDRATD-----VD 589
+ E + +I G G L+ ++V +R+ +R TD
Sbjct: 528 MTEAEYQTSIQEKLPLIIGSSAAGLVFLIAVVVIAIVCNRRRGFERADSEYTDKLQHYTS 587
Query: 590 REDKLWLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQD 649
+K Y+D YEDP + +F +E+D + + ++ VIG GEFGEV G L+LP +
Sbjct: 588 GHMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR 647
Query: 650 CKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGA 709
VAIKTLK Q +FL EA+IMGQF HP+++HLEGVVTK P+MIITEFMENG+
Sbjct: 648 EIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGS 707
Query: 710 LDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFG 769
LD+FLR+ + Q QLV ML+GIA+GM YL++ NYVHRDLAARNILVN NL CKVSDFG
Sbjct: 708 LDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFG 767
Query: 770 LTRLLDD--FDGTYETQ-GGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKP 826
L+R L+D D TY + GGKIPIRWTAPEAI +R FT+ASDVWS+GIVMWEV+S+G++P
Sbjct: 768 LSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERP 827
Query: 827 YGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLAN 886
Y +M+NQ+V+ +IE YRLPPP+DCP+ L++LM +CW DR RP F ++ L++++ N
Sbjct: 828 YWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRN 887
Query: 887 PHSLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVL 946
P+SL+ +A + L L + D + TV EWLE+I+M +Y F +AG + + V
Sbjct: 888 PNSLKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVS 947
Query: 947 ELTAEDLTQMGITLPGHQKRILCSIQ 972
++ ED+ ++G+TL GHQK+IL SIQ
Sbjct: 948 QMMMEDILRVGVTLAGHQKKILNSIQ 973
>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
sapiens]
Length = 986
Score = 722 bits (1863), Expect = 0.0
Identities = 414/985 (42%), Positives = 581/985 (58%), Gaps = 39/985 (3%)
Query: 9 LGLVLLLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LNGTPLYMYQ 67
LG LLL P A E TLMD++ A ELGW++ PP GW E N + YQ
Sbjct: 6 LGAALLLL----PLLAAVEETLMDSTTATAELGWMVHPPS-GWEEVSGYDENMNTIRTYQ 60
Query: 68 DCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYM 127
C + ++WLR+ +I R A R+HVE++F+VRDC S P G CKETFNL Y
Sbjct: 61 VCNVF-ESSQNNWLRTKFIRR-RGAHRIHVEMKFSVRDCSSIPSVPG--SCKETFNLYYY 116
Query: 128 ESDQDVGIQ-----LRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLY 182
E+D D + + P + KV T+AAD+SF+ DL +K+N E S G ++R G Y
Sbjct: 117 EADFDSATKTFPNWMENP-WVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFY 175
Query: 183 LAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGP--AGLVEVAGTCLPHARASPR 240
LAF + G C++L++VRVFY++CP + A F +TL G LV G+C+ +A
Sbjct: 176 LAFQDYGGCMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDV 235
Query: 241 PSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQ 300
P +++C+ DGEWLVP+GRC C+ G+E +G C CPSG+++ + C CP
Sbjct: 236 PI---KLYCNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPIN 292
Query: 301 STAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGG 360
S SEGAT C C +G+YRA + + CT PSAP+ + S + T L L W PP D+GG
Sbjct: 293 SRTTSEGATNCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGG 352
Query: 361 RQDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVE 420
R+D+ Y++ C C G C CG V ++P GLT P ++++ L + YTF ++
Sbjct: 353 REDLVYNIICKSC---GSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQ 409
Query: 421 AQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSP-GANL 479
A NGV+ SV+I+ A + + V + + L+W S+P P G L
Sbjct: 410 AVNGVTDQSPFSPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSW--SQPDQPNGVIL 467
Query: 480 TYELHVLNQDEERYQM--VLEPR--VLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRT 535
YEL ++ Y + P V + L+ Y+ +VR T G G +S F+T
Sbjct: 468 DYELQYYEKELSEYNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQT 527
Query: 536 SPPVSRGLTGGEIVAVIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRATD-----VDR 590
+ E + +I G + L +V + R+ +R TD
Sbjct: 528 MTEAEYQTSIQEKLPLIIGSSAAGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSG 587
Query: 591 EDKLWLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDC 650
+K Y+D YEDP + +F +E+D + + ++ VIG GEFGEV G L+LP +
Sbjct: 588 HMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKRE 647
Query: 651 KTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGAL 710
VAIKTLK Q +FL EA+IMGQF HP+++HLEGVVTK P+MIITEFMENG+L
Sbjct: 648 IFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSL 707
Query: 711 DAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGL 770
D+FLR+ + Q QLV ML+GIA+GM YL++ NYVHRDLAARNILVN NL CKVSDFGL
Sbjct: 708 DSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGL 767
Query: 771 TRLLDD--FDGTYETQ-GGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPY 827
+R L+D D TY + GGKIPIRWTAPEAI +R FT+ASDVWS+GIVMWEV+S+G++PY
Sbjct: 768 SRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPY 827
Query: 828 GEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANP 887
+M+NQ+V+ +IE YRLPPP+DCP+ L++LM +CW DR RP F ++ L++++ NP
Sbjct: 828 WDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 887
Query: 888 HSLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLE 947
+SL+ +A + L L + D + TV EWLE+I+M +Y F +AG + + V +
Sbjct: 888 NSLKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQ 947
Query: 948 LTAEDLTQMGITLPGHQKRILCSIQ 972
+ ED+ ++G+TL GHQK+IL SIQ
Sbjct: 948 MMMEDILRVGVTLAGHQKKILNSIQ 972
>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
Length = 987
Score = 707 bits (1824), Expect = 0.0
Identities = 413/990 (41%), Positives = 575/990 (58%), Gaps = 51/990 (5%)
Query: 12 VLLLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQILNGTP--LYMYQDC 69
VLL A L A A E TL++T +L W+ P DG E+ L+ + Y+ C
Sbjct: 5 VLLCWASL---AAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVC 61
Query: 70 PMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYMES 129
+Q HWLR+ W+ R A V+ L+FT+ +C S P CKETF + Y ES
Sbjct: 62 DVQRAPGQAHWLRTGWVPR-RGAVHVYATLRFTMLECLSLPRAGR--SCKETFTVFYYES 118
Query: 130 DQDVGIQLRRPLFQ----KVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLAF 185
D D L + KV TVAA+ R + K+NV+ LG L++ G YLAF
Sbjct: 119 DADTATALTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAF 178
Query: 186 HNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGPAGLVEVAGTCLPHARASPRPSGAP 245
+ GAC+AL+S+ +FY++C + L +FP+T+P +V VAG+C+ A +P PS P
Sbjct: 179 QDQGACMALLSLHLFYKKCAQLTVNLTRFPETVPREL-VVPVAGSCVVDAVPAPGPS--P 235
Query: 246 RMHCSPDGEWLV-PVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTAE 304
++C DG+W PV C C PG+E C AC G+++ C CP S +
Sbjct: 236 SLYCREDGQWAEQPVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSN 295
Query: 305 SEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGRQDV 364
+ G+ +C C G++RA + CT PPSAPR++ +G+ L L W P ++GGR+D+
Sbjct: 296 TIGSAVCQCRVGYFRARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDL 355
Query: 365 RYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQNG 424
Y++RC +C+ GG C PCG + F PG R L P V V GL P YTF V A NG
Sbjct: 356 TYALRCRECR----PGGSCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNG 411
Query: 425 VSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSP-GANLTYEL 483
VS L + V+++ + +R+ + P L L WA PR+P GA L YE+
Sbjct: 412 VSSLATGPVPFEPVNVTTDREVPPAVSDIRVTRSSPSSLSLAWAV--PRAPSGAVLDYEV 469
Query: 484 HVLNQDEE-----RYQMVLEPRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPP 538
+ E R+ E R L L+ +Y+V+VR + G GPF +H +T
Sbjct: 470 KYHEKGAEGPSSVRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLD 529
Query: 539 VSRGLTGGEIVAVIFGL-LLGAALLLGILVFRSRRAQRQRQQRQRDRATDVDREDKLWL- 596
S G E +A+I G ++G L+L ++V ++Q R+ + + D+ + +
Sbjct: 530 ESEGWR--EQLALIAGTAVVGVVLVLVVIVVAVLCLRKQSNGREAEYS---DKHGQYLIG 584
Query: 597 ---KPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTV 653
K Y+D YEDP + +F +E+D +++ ++ VIG GEFGEV RG L+ P + V
Sbjct: 585 HGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCV 644
Query: 654 AIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAF 713
AIKTLK Q FL EA+IMGQF HP+I+ LEGVVT P+MI+TEFMENGALD+F
Sbjct: 645 AIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSF 704
Query: 714 LREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRL 773
LR + Q QLV ML+GIASGM YL+ +YVHRDLAARNILVN NL CKVSDFGL+R
Sbjct: 705 LRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRF 764
Query: 774 LDD--FDGTYETQ-GGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEM 830
L++ D TY + GGKIPIRWTAPEAIA R FT+ASD WS+GIVMWEV+SFG++PY +M
Sbjct: 765 LEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDM 824
Query: 831 SNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSL 890
SNQ+V+ +IE YRLPPP DCP L++LM +CW DR RP F ++ + L++++ NP SL
Sbjct: 825 SNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASL 884
Query: 891 RTIANFD-----PRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECV 945
+ +A + P + R P S + +V EWL +I+M RY F +AG + E V
Sbjct: 885 KIVARENGGASHPLLDQRQPHYSA-----FGSVGEWLRAIKMGRYEESFAAAGFGSFELV 939
Query: 946 LELTAEDLTQMGITLPGHQKRILCSIQGFK 975
+++AEDL ++G+TL GHQK+IL S+Q K
Sbjct: 940 SQISAEDLLRIGVTLAGHQKKILASVQHMK 969
>gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
Length = 1008
Score = 701 bits (1809), Expect = 0.0
Identities = 409/990 (41%), Positives = 571/990 (57%), Gaps = 45/990 (4%)
Query: 14 LLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LNGTPLYMYQDCPMQ 72
LL P PG A+EV L+D+ +Q ELGW P +GW E + + P+ YQ C +
Sbjct: 23 LLLGPWRPGT-AEEVILLDSKASQAELGWTA-LPSNGWEEISGVDEHDRPIRTYQVCNVL 80
Query: 73 GRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYMESDQD 132
+ D+WL++ WI RG R+ VELQFT+RDC S PG AG CKETFN+ Y+E++ D
Sbjct: 81 -EPNQDNWLQTGWISRGR-GQRIFVELQFTLRDCSSIPGAAGT--CKETFNVYYLETEAD 136
Query: 133 VG-----IQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLAFHN 187
+G + RP +K+ T+AAD+SFT DL +KLN E +G L+RRG +LAF +
Sbjct: 137 LGRGRPRLGGSRP--RKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQD 194
Query: 188 PGACVALVSVRVFYQRCPETLNGLAQFPDTLPGPA--GLVEVAGTCLPHARASPRPSGAP 245
GACVALVSVRV+Y++C T+ GLA FP T A LVEVAGTC+ H+ P P
Sbjct: 195 VGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEP--GSPP 252
Query: 246 RMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTAES 305
RMHC DGEWLVPVGRC C G++E G+ C ACP G Y++ P C CP+ S A
Sbjct: 253 RMHCGADGEWLVPVGRCSCSAGFQE--RGDFCEACPPGFYKVSPRRPLCSPCPEHSRALE 310
Query: 306 EGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQL--SLRWEPPADTGGRQD 363
+T C C+ + R+P + P +CT PPSAPR+L +S S + L LRW PPAD+GGR D
Sbjct: 311 NASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSD 370
Query: 364 VRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQN 423
V YS+ C +C G G C+PCG V F P GL A + L P A YT V A N
Sbjct: 371 VTYSLLCLRC-GREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALN 429
Query: 424 GVSG-LGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPR-SPGANLT- 480
GVSG ++G V++S G +R + EP+ + L+W P +PGAN T
Sbjct: 430 GVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTE 489
Query: 481 YELHVLN--QDEERYQMVLE--PRVLLTELQPDTTYIVRVRMLTPLGPG----PFSPDHE 532
YE+ Q E+ Y MV P V +T L+P T Y+ ++R +P GP F+P E
Sbjct: 490 YEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASP-GPSWEAQSFNPSIE 548
Query: 533 FRTSPPVSRGLTGGEIVAVIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRATDVDRED 592
+T + G V+ + + A L+LG ++ S A +R D E+
Sbjct: 549 VQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVM--SVLAIWRRPCSYGKGGGDAHDEE 606
Query: 593 KLWL-------KPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRL 645
+L+ + ++D Q+ D Q F +ELD + ++ +G G FGE+ G L+L
Sbjct: 607 ELYFHFKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGCLQL 666
Query: 646 PSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFM 705
P + VA+ L+D++ Q FL EA +GQF H HI+ LEGVVT+ +MI+TE+M
Sbjct: 667 PGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYM 726
Query: 706 ENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKV 765
+GALD FLR E QLV GQL+ +L G+AS M YLS YVHR LAAR++LV+ +L CK+
Sbjct: 727 SHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKI 786
Query: 766 SDFGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDK 825
S FG D + Y T G+ P W APE + F++ASDVWSFGI+MWEV++FG++
Sbjct: 787 SGFGRGPR-DRSEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGER 845
Query: 826 PYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLA 885
PY +MS Q+V+K++EDG+RLPPP +CP L+ LM +CW D RP F ++ + L +++
Sbjct: 846 PYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQ 905
Query: 886 NPHSLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECV 945
+P + PR L + S + +V WLE++ + RY F +AG ++E V
Sbjct: 906 DPEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYGSLEAV 965
Query: 946 LELTAEDLTQMGITLPGHQKRILCSIQGFK 975
E+TA+DL +GI+L H++ +L I +
Sbjct: 966 AEMTAQDLVSLGISLAEHREALLSGISALQ 995
>gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]
Length = 1021
Score = 634 bits (1635), Expect = 0.0
Identities = 377/1000 (37%), Positives = 533/1000 (53%), Gaps = 75/1000 (7%)
Query: 25 AKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQILNGTPLYM-YQDCPMQGR---RDTDHW 80
A E L+DT+ E+GWL PP GW E + + L ++ C + G D+W
Sbjct: 31 ALEEVLLDTTGETSEIGWLTYPP-GGWDEVSVLDDQRRLTRTFEACHVAGAPPGTGQDNW 89
Query: 81 LRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYMESDQ----DVGIQ 136
L+++++ R A R H+ L F+VR C S G C+ETF L Y ++++ D
Sbjct: 90 LQTHFVER-RGAQRAHIRLHFSVRACSSLGVSGGT--CRETFTLYYRQAEEPDSPDSVSS 146
Query: 137 LRRPLFQKVTTVAADQSFTIRDLVSGS------------------VKLNVERCSLGRLTR 178
+ KV T+AAD+SF S S ++LNV+ S G LT+
Sbjct: 147 WHLKRWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPHGAGQRAGLQLNVKERSFGPLTQ 206
Query: 179 RGLYLAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGPAG---LVEVAGTCLPHA 235
RG Y+AF + GAC+ALV+VR+F CP L A FP+T AG LV GTC+ HA
Sbjct: 207 RGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQASGAGGASLVAAVGTCVAHA 266
Query: 236 RASPRPSGA------PRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDM 289
G PR+HC+ +G+W+V VG C C+PGY+ +AC ACP G Y+
Sbjct: 267 EPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDKACQACPRGLYKSSA 326
Query: 290 DTPHCLTCPQQSTAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLS 349
C CP +S A + A +C C G YRA + P+ CTGPPSAP+ L F G+ L
Sbjct: 327 GNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSAPQELWFEVQGSALM 386
Query: 350 LRWEPPADTGGRQDVRYSVRCSQCQGTAQD----GGPCQPCGVGVHFSPGARGLTTPAVH 405
L W P + GGR D+ ++V C +C+G + GG C C VHF P RGLT V
Sbjct: 387 LHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVHFDPRQRGLTESRVL 446
Query: 406 VNGLEPYANYTFNVEAQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLEL 465
V GL + Y V+A NGVS L + ++++S H + + V + + +
Sbjct: 447 VGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVPVVHQVSRASNSITV 506
Query: 466 TWAGSRPRSPGAN-LTYELHVLNQ-DEERYQMVLEPRV---LLTELQPDTTYIVRVRMLT 520
+W +P N L Y+L +Q ++E + L +T+L P Y +VR T
Sbjct: 507 SWP--QPDQTNGNILDYQLRYYDQAEDESHSFTLTSETNTATVTQLSPGHIYGFQVRART 564
Query: 521 PLGPGPFSPDHEFRTSP--------PVSRGLTGGEIVAVIFGLLLGAALLLGILVFRSRR 572
G GP+ F+T P P L G I+ + LLL A +L ++ R RR
Sbjct: 565 AAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGSILGALAFLLLAAITVLAVVFQRKRR 624
Query: 573 AQRQRQQRQRDRATDVDREDKLWLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGE 632
+Q Q+ + L +K Y+D YEDP Q + RE+DPA++ ++ VIG
Sbjct: 625 GTGYTEQLQQYSSPG------LGVKYYIDPSTYEDPCQAIRELAREVDPAYIKIEEVIGT 678
Query: 633 GEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVV 692
G FGEV +G L+ + +TVAI+ L FL A ++GQF HP+IL LEGVV
Sbjct: 679 GSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGRAAVLGQFQHPNILRLEGVV 738
Query: 693 TKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAA 752
TK +P+M++TEFME G LD+FLR+RE Q QLVAM +G+A+ M YLS+ +VHR L+A
Sbjct: 739 TKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRSLSA 798
Query: 753 RNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSF 812
++LVN +L CKV+ G + QG +RW APE IAH TT+SDVWSF
Sbjct: 799 HSVLVNSHLVCKVARLG-----------HSPQGPSCLLRWAAPEVIAHGKHTTSSDVWSF 847
Query: 813 GIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPH 872
GI+MWEV+S+G++PY +MS QEV+ +IE +RLPPP CP L+ LM + W DRARRPH
Sbjct: 848 GILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRARRPH 907
Query: 873 FQKLQAHLEQLLANPHSLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYIL 932
F +L A ++++ P +L+ + R + L + D + WL +I ++ Y
Sbjct: 908 FDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSAIGLECYQD 967
Query: 933 HFHSAGLDTMECVLELTAEDLTQMGITLPGHQKRILCSIQ 972
+F GL T V +L+ EDL +GITL GHQK++L IQ
Sbjct: 968 NFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQ 1007
>gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo
sapiens]
Length = 539
Score = 383 bits (983), Expect = e-106
Identities = 218/539 (40%), Positives = 307/539 (56%), Gaps = 28/539 (5%)
Query: 11 LVLLLCAPLPPGAR-----AKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LNGTPLY 64
L+LL C+ L + EV L+D+ QGELGW+ P GW E + + TP+
Sbjct: 8 LLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWI-SYPSHGWEEISGVDEHYTPIR 66
Query: 65 MYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNL 124
YQ C + ++WLR+NW+ R A +++VEL+FT+RDC S P G CKETFNL
Sbjct: 67 TYQVCNVMDHSQ-NNWLRTNWVPRNS-AQKIYVELKFTLRDCNSIPLVLGT--CKETFNL 122
Query: 125 LYMESDQDVGIQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLA 184
YMESD D G++ R F K+ T+AAD+SFT DL +KLN E +G + ++G YLA
Sbjct: 123 YYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLA 182
Query: 185 FHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLP-GPAGLVEVAGTCLPHARASPRPSG 243
F + GACVALVSVRV++++CP T+ LA FPDT+P LVEV G+C+ ++ +
Sbjct: 183 FQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNS----KEED 238
Query: 244 APRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTA 303
PRM+CS +GEWLVP+G+C C GYEE G C AC G Y+ C CP S+
Sbjct: 239 PPRMYCSTEGEWLVPIGKCSCNAGYEE--RGFMCQACRPGFYKALDGNMKCAKCPPHSST 296
Query: 304 ESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGRQD 363
+ +G+ C CE+ ++RA + P +ACT PPS+PRN+ + + T + L W P DTGGR+D
Sbjct: 297 QEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKD 356
Query: 364 VRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQN 423
V +++ C +C + C+PC V F P GLT V V L + NYTF ++A N
Sbjct: 357 VTFNIICKKCGWNIKQ---CEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN 413
Query: 424 GVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSP-GANLTYE 482
GVS L S +VSI+ A L+++ + + L+W P P G L YE
Sbjct: 414 GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSW--QEPEHPNGIILDYE 471
Query: 483 L-HVLNQDEERYQMVLEPR---VLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSP 537
+ + Q++E +L R V ++ L+PDT Y+ ++R T G G S EF TSP
Sbjct: 472 VKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSP 530
>gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo
sapiens]
Length = 495
Score = 326 bits (835), Expect = 7e-89
Identities = 174/422 (41%), Positives = 244/422 (57%), Gaps = 17/422 (4%)
Query: 27 EVTLMDTSKAQGELGWLLDPPKDGWSEQQQILNG-TPLYMYQDCPMQGRRDTDHWLRSNW 85
EV L+DTS G+ GWL P GW ++ P++ YQ C + ++WLR++W
Sbjct: 31 EVNLLDTSTIHGDWGWLTYPAH-GWDSINEVDESFQPIHTYQVCNVMSPNQ-NNWLRTSW 88
Query: 86 IYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYMESDQDVGIQLRRPLFQKV 145
+ R + A RV+ E++FT+RDC S PG G CKETFNL Y+ESD+D+G + F K+
Sbjct: 89 VPR-DGARRVYAEIKFTLRDCNSMPGVLGT--CKETFNLYYLESDRDLGASTQESQFLKI 145
Query: 146 TTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLAFHNPGACVALVSVRVFYQRCP 205
T+AAD+SFT DL +KLN E S+G L++RG YLAF + GAC+A++S+R++Y++CP
Sbjct: 146 DTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCP 205
Query: 206 ETLNGLAQFPDTLPG--PAGLVEVAGTCLPHARASPRPSGAPRMHCSPDGEWLVPVGRCH 263
+ LA F + + G + LVEV G C+ H+ P+M+CS +GEWLVP+G+C
Sbjct: 206 AMVRNLAAFSEAVTGADSSSLVEVRGQCVRHS----EERDTPKMYCSAEGEWLVPIGKCV 261
Query: 264 CEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTAESEGATICTCESGHYRAPGE 323
C GYEE +ACVAC G Y+ C CP S + + A C C+ +YRA +
Sbjct: 262 CSAGYEE--RRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALD 319
Query: 324 GPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGRQDVRYSVRCSQCQGTAQDGGPC 383
P ACT PPSAP NL S +GT ++L W PP D GGR D+ Y+ C +C C
Sbjct: 320 PPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWAL---SRC 376
Query: 384 QPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQNGVSGLGSSGHASTSVSISMG 443
+ CG G F P L ++ V L + NY+F +EA NGVS L + V+I+
Sbjct: 377 EACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTN 436
Query: 444 HA 445
A
Sbjct: 437 QA 438
>gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]
Length = 1074
Score = 232 bits (591), Expect = 1e-60
Identities = 126/307 (41%), Positives = 177/307 (57%), Gaps = 7/307 (2%)
Query: 578 QQRQRDRATDVDREDKLWLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGE 637
+Q R A V D Y ++ ED E+ + + IGEG+FG+
Sbjct: 403 KQGMRTHAVSVSETDD-----YAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGD 457
Query: 638 VYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKP 697
V++G P VAIKT K+ + FL+EA M QF HPHI+ L GV+T+ P
Sbjct: 458 VHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITEN-P 516
Query: 698 IMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILV 757
+ II E G L +FL+ R+ L L+ +++ + YL + +VHRD+AARN+LV
Sbjct: 517 VWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLV 576
Query: 758 NQNLCCKVSDFGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMW 817
+ N C K+ DFGL+R ++D Y+ GK+PI+W APE+I R FT+ASDVW FG+ MW
Sbjct: 577 SSNDCVKLGDFGLSRYMED-STYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMW 635
Query: 818 EVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQ 877
E+L G KP+ + N +V+ IE+G RLP P +CP LY LM CWAYD +RRP F +L+
Sbjct: 636 EILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELK 695
Query: 878 AHLEQLL 884
A L +L
Sbjct: 696 AQLSTIL 702
>gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]
Length = 1052
Score = 232 bits (591), Expect = 1e-60
Identities = 126/307 (41%), Positives = 177/307 (57%), Gaps = 7/307 (2%)
Query: 578 QQRQRDRATDVDREDKLWLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGE 637
+Q R A V D Y ++ ED E+ + + IGEG+FG+
Sbjct: 381 KQGMRTHAVSVSETDD-----YAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGD 435
Query: 638 VYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKP 697
V++G P VAIKT K+ + FL+EA M QF HPHI+ L GV+T+ P
Sbjct: 436 VHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITEN-P 494
Query: 698 IMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILV 757
+ II E G L +FL+ R+ L L+ +++ + YL + +VHRD+AARN+LV
Sbjct: 495 VWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLV 554
Query: 758 NQNLCCKVSDFGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMW 817
+ N C K+ DFGL+R ++D Y+ GK+PI+W APE+I R FT+ASDVW FG+ MW
Sbjct: 555 SSNDCVKLGDFGLSRYMED-STYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMW 613
Query: 818 EVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQ 877
E+L G KP+ + N +V+ IE+G RLP P +CP LY LM CWAYD +RRP F +L+
Sbjct: 614 EILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELK 673
Query: 878 AHLEQLL 884
A L +L
Sbjct: 674 AQLSTIL 680
>gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]
Length = 295
Score = 228 bits (582), Expect = 2e-59
Identities = 130/267 (48%), Positives = 168/267 (62%), Gaps = 18/267 (6%)
Query: 14 LLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LNGTPLYMYQDCPMQ 72
LL P PG A+EV L+D+ +Q ELGW P +GW E + + P+ YQ C +
Sbjct: 23 LLLGPWRPGT-AEEVILLDSKASQAELGWTA-LPSNGWEEISGVDEHDRPIRTYQVCNVL 80
Query: 73 GRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYMESDQD 132
+ D+WL++ WI RG R+ VELQFT+RDC S PG AG CKETFN+ Y+E++ D
Sbjct: 81 -EPNQDNWLQTGWISRGR-GQRIFVELQFTLRDCSSIPGAAGT--CKETFNVYYLETEAD 136
Query: 133 VG-----IQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLAFHN 187
+G + RP +K+ T+AAD+SFT DL +KLN E +G L+RRG +LAF +
Sbjct: 137 LGRGRPRLGGSRP--RKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQD 194
Query: 188 PGACVALVSVRVFYQRCPETLNGLAQFPDTLPGPA--GLVEVAGTCLPHARASPRPSGAP 245
GACVALVSVRV+Y++C T+ GLA FP T A LVEVAGTC+ H+ P P
Sbjct: 195 VGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEG--EPGSPP 252
Query: 246 RMHCSPDGEWLVPVGRCHCEPGYEEGG 272
RMHC DGEWLVPVGRC C G++E G
Sbjct: 253 RMHCGADGEWLVPVGRCSCSAGFQERG 279
>gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens]
Length = 822
Score = 221 bits (563), Expect = 3e-57
Identities = 115/258 (44%), Positives = 163/258 (63%), Gaps = 7/258 (2%)
Query: 624 LMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHP 683
+++ ++G+G FGEVY+GTL+ D +VA+KT K+ P FL+EA I+ Q+ HP
Sbjct: 563 VILGELLGKGNFGEVYKGTLK----DKTSVAVKTCKEDLPQELKIKFLQEAKILKQYDHP 618
Query: 684 HILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNH 743
+I+ L GV T+R+P+ II E + G FLR ++D+L QLV A+GM YL +
Sbjct: 619 NIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQLVKFSLDAAAGMLYLESK 678
Query: 744 NYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGGK-IPIRWTAPEAIAHRI 802
N +HRDLAARN LV +N K+SDFG++R D G Y + G K IPI+WTAPEA+ +
Sbjct: 679 NCIHRDLAARNCLVGENNVLKISDFGMSRQED--GGVYSSSGLKQIPIKWTAPEALNYGR 736
Query: 803 FTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNC 862
+++ SDVWSFGI++WE S G PY M+NQ+ + +E GYR+ P CP + ++M C
Sbjct: 737 YSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQHCPEDISKIMMKC 796
Query: 863 WAYDRARRPHFQKLQAHL 880
W Y RP F +LQ L
Sbjct: 797 WDYKPENRPKFSELQKEL 814
>gi|27597078 TYRO3 protein tyrosine kinase [Homo sapiens]
Length = 890
Score = 216 bits (550), Expect = 8e-56
Identities = 186/623 (29%), Positives = 285/623 (45%), Gaps = 76/623 (12%)
Query: 308 ATICTCESGHYR--APGEGPQVACTGPPSAPRNLSFSA-SGTQLSLRWEPPADTGGRQDV 364
+T+ +CE+ + + A V P+AP N++ + S + S+ W P AD GR +
Sbjct: 198 STMFSCEAHNLKGLASSRTATVHLQALPAAPFNITVTKLSSSNASVAWMPGAD--GRALL 255
Query: 365 RYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHV-------NGLEPYANYTF 417
Q C V V +PG + V V L P NY+
Sbjct: 256 -------------------QSCTVQVTQAPGGWEVLAVVVPVPPFTCLLRDLVPATNYSL 296
Query: 418 NVEAQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSP-- 475
V N LG S +A + G A + + +L ++ + L L W P +P
Sbjct: 297 RVRCANA---LGPSPYADWVPFQTKGLAPASAPQNLHAIRTDSG-LILEWEEVIPEAPLE 352
Query: 476 GANLTYELHVLNQDEERYQMVLE-PRVLLTELQPDTTYIVRVRMLTPLGPGPFSP----- 529
G Y+L + + + ++ +E R LT P IVRV + +G GP+S
Sbjct: 353 GPLGPYKLSWVQDNGTQDELTVEGTRANLTGWDPQKDLIVRVCVSNAVGCGPWSQPLVVS 412
Query: 530 --DHEFRTSPPVSRGLTGGEIVAVIFGLLLGAALLLGILVFRSRRAQRQRQQRQRD---- 583
D + PP SR ++ V+ L+ AAL L ++ R RR + + Q
Sbjct: 413 SHDRAGQQGPPHSRTSWVPVVLGVLTALVTAAALAL--ILLRKRRKETRFGQAFDSVMAR 470
Query: 584 --------RATDVDREDKLWLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEF 635
A +RE ++ +D D + L+ + + ++G+GEF
Sbjct: 471 GEPAVHFRAARSFNRERPERIEATLDSLGISDELKEKLEDVL-IPEQQFTLGRMLGKGEF 529
Query: 636 GEVYRGTLRLPSQDCKTVAIKTLK-DTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTK 694
G V L+ VA+K LK D FLREA M +F HPH+ L GV +
Sbjct: 530 GSVREAQLKQEDGSFVKVAVKMLKADIIASSDIEEFLREAACMKEFDHPHVAKLVGVSLR 589
Query: 695 -----RKPI-MIITEFMENGALDAFLR-----EREDQLVPGQLVAMLQGIASGMNYLSNH 743
R PI M+I FM++G L AFL E L L+ + IA GM YLS+
Sbjct: 590 SRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQTLIRFMVDIACGMEYLSSR 649
Query: 744 NYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQG--GKIPIRWTAPEAIAHR 801
N++HRDLAARN ++ +++ V+DFGL+R + + G Y QG K+P++W A E++A
Sbjct: 650 NFIHRDLAARNCMLAEDMTVCVADFGLSRKI--YSGDYYRQGCASKLPVKWLALESLADN 707
Query: 802 IFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKN 861
++T SDVW+FG+ MWE+++ G PY + N E+ + G RL P +C +Y+LM
Sbjct: 708 LYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLIGGNRLKQPPECMEDVYDLMYQ 767
Query: 862 CWAYDRARRPHFQKLQAHLEQLL 884
CW+ D +RP F L+ LE +L
Sbjct: 768 CWSADPKQRPSFTCLRMELENIL 790
>gi|219842236 feline sarcoma oncogene isoform 4 [Homo sapiens]
Length = 694
Score = 215 bits (548), Expect = 1e-55
Identities = 110/262 (41%), Positives = 163/262 (62%), Gaps = 7/262 (2%)
Query: 624 LMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHP 683
L++ IG G FGEV+ G LR D VA+K+ ++T P FL+EA I+ Q+SHP
Sbjct: 433 LVLGEQIGRGNFGEVFSGRLRA---DNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHP 489
Query: 684 HILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNH 743
+I+ L GV T+++PI I+ E ++ G FLR +L L+ M+ A+GM YL +
Sbjct: 490 NIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESK 549
Query: 744 NYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGG--KIPIRWTAPEAIAHR 801
+HRDLAARN LV + K+SDFG++R ++ DG Y GG ++P++WTAPEA+ +
Sbjct: 550 CCIHRDLAARNCLVTEKNVLKISDFGMSR--EEADGVYAASGGLRQVPVKWTAPEALNYG 607
Query: 802 IFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKN 861
+++ SDVWSFGI++WE S G PY +SNQ+ + +E G RLP P CP ++ LM+
Sbjct: 608 RYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQ 667
Query: 862 CWAYDRARRPHFQKLQAHLEQL 883
CWAY+ +RP F + L+ +
Sbjct: 668 CWAYEPGQRPSFSTIYQELQSI 689
>gi|219842233 feline sarcoma oncogene isoform 3 [Homo sapiens]
Length = 752
Score = 215 bits (548), Expect = 1e-55
Identities = 110/262 (41%), Positives = 163/262 (62%), Gaps = 7/262 (2%)
Query: 624 LMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHP 683
L++ IG G FGEV+ G LR D VA+K+ ++T P FL+EA I+ Q+SHP
Sbjct: 491 LVLGEQIGRGNFGEVFSGRLRA---DNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHP 547
Query: 684 HILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNH 743
+I+ L GV T+++PI I+ E ++ G FLR +L L+ M+ A+GM YL +
Sbjct: 548 NIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESK 607
Query: 744 NYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGG--KIPIRWTAPEAIAHR 801
+HRDLAARN LV + K+SDFG++R ++ DG Y GG ++P++WTAPEA+ +
Sbjct: 608 CCIHRDLAARNCLVTEKNVLKISDFGMSR--EEADGVYAASGGLRQVPVKWTAPEALNYG 665
Query: 802 IFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKN 861
+++ SDVWSFGI++WE S G PY +SNQ+ + +E G RLP P CP ++ LM+
Sbjct: 666 RYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQ 725
Query: 862 CWAYDRARRPHFQKLQAHLEQL 883
CWAY+ +RP F + L+ +
Sbjct: 726 CWAYEPGQRPSFSTIYQELQSI 747
>gi|219842230 feline sarcoma oncogene isoform 2 [Homo sapiens]
Length = 764
Score = 215 bits (548), Expect = 1e-55
Identities = 110/262 (41%), Positives = 163/262 (62%), Gaps = 7/262 (2%)
Query: 624 LMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHP 683
L++ IG G FGEV+ G LR D VA+K+ ++T P FL+EA I+ Q+SHP
Sbjct: 503 LVLGEQIGRGNFGEVFSGRLRA---DNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHP 559
Query: 684 HILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNH 743
+I+ L GV T+++PI I+ E ++ G FLR +L L+ M+ A+GM YL +
Sbjct: 560 NIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESK 619
Query: 744 NYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGG--KIPIRWTAPEAIAHR 801
+HRDLAARN LV + K+SDFG++R ++ DG Y GG ++P++WTAPEA+ +
Sbjct: 620 CCIHRDLAARNCLVTEKNVLKISDFGMSR--EEADGVYAASGGLRQVPVKWTAPEALNYG 677
Query: 802 IFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKN 861
+++ SDVWSFGI++WE S G PY +SNQ+ + +E G RLP P CP ++ LM+
Sbjct: 678 RYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQ 737
Query: 862 CWAYDRARRPHFQKLQAHLEQL 883
CWAY+ +RP F + L+ +
Sbjct: 738 CWAYEPGQRPSFSTIYQELQSI 759
>gi|4503687 feline sarcoma oncogene isoform 1 [Homo sapiens]
Length = 822
Score = 215 bits (548), Expect = 1e-55
Identities = 110/262 (41%), Positives = 163/262 (62%), Gaps = 7/262 (2%)
Query: 624 LMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHP 683
L++ IG G FGEV+ G LR D VA+K+ ++T P FL+EA I+ Q+SHP
Sbjct: 561 LVLGEQIGRGNFGEVFSGRLRA---DNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHP 617
Query: 684 HILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNH 743
+I+ L GV T+++PI I+ E ++ G FLR +L L+ M+ A+GM YL +
Sbjct: 618 NIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESK 677
Query: 744 NYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGG--KIPIRWTAPEAIAHR 801
+HRDLAARN LV + K+SDFG++R ++ DG Y GG ++P++WTAPEA+ +
Sbjct: 678 CCIHRDLAARNCLVTEKNVLKISDFGMSR--EEADGVYAASGGLRQVPVKWTAPEALNYG 735
Query: 802 IFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKN 861
+++ SDVWSFGI++WE S G PY +SNQ+ + +E G RLP P CP ++ LM+
Sbjct: 736 RYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQ 795
Query: 862 CWAYDRARRPHFQKLQAHLEQL 883
CWAY+ +RP F + L+ +
Sbjct: 796 CWAYEPGQRPSFSTIYQELQSI 817
>gi|66932918 MER receptor tyrosine kinase precursor [Homo sapiens]
Length = 999
Score = 214 bits (546), Expect = 2e-55
Identities = 188/629 (29%), Positives = 302/629 (48%), Gaps = 75/629 (11%)
Query: 343 ASGTQLSLRW--EPPADTGGRQDVRYSVRCSQCQGTAQDG-GPCQPCGVGV-HFSPGARG 398
+ G Q++++ PP + R +S+ S G DG P + C + V P + G
Sbjct: 273 SKGVQINIKAIPSPPTEVSIRNSTAHSILISWVPGF--DGYSPFRNCSIQVKEADPLSNG 330
Query: 399 ----LTTPAV----HVNGLEPYANYTFNVEAQNGVSG-------LGSSGHASTSVS---I 440
T A+ + L+ ANY+ V N + L S+ + SV+ +
Sbjct: 331 SVMIFNTSALPHLYQIKQLQALANYSIGVSCMNEIGWSAVSPWILASTTEGAPSVAPLNV 390
Query: 441 SMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRS--PGANLTYEL-HVLNQDEERYQMVL 497
++ ES + +R +K +Q + G R A ++ EL + Q+ R ++ +
Sbjct: 391 TVFLNESSDNVDIRWMKPPTKQQDGELVGYRISHVWQSAGISKELLEEVGQNGSRARISV 450
Query: 498 EPRVLLTELQPDTTYIVRVRMLTPLGPGPFS-------PDHEFRTSPPVSRGLTGG-EIV 549
+ + T VR+ +T G GPFS P H + P S G + V
Sbjct: 451 QVH--------NATCTVRIAAVTRGGVGPFSDPVKIFIPAHGWVDYAPSSTPAPGNADPV 502
Query: 550 AVIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRA-TDVDRE-------DKLWLKPYVD 601
+IFG G +L+G++++ S +++ Q+ + A T+ D E K + + ++
Sbjct: 503 LIIFGCFCGF-ILIGLILYISLAIRKRVQETKFGNAFTEEDSELVVNYIAKKSFCRRAIE 561
Query: 602 LQAYEDPAQGALDFTRE---LDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTL 658
L + L E +D L++ ++GEGEFG V G L+ VA+KT+
Sbjct: 562 LTLHSLGVSEELQNKLEDVVIDRNLLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTM 621
Query: 659 K-DTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKR------KPIMIITEFMENGALD 711
K D S + FL EA M FSHP+++ L GV + KP M+I FM+ G L
Sbjct: 622 KLDNSSQREIEEFLSEAACMKDFSHPNVIRLLGVCIEMSSQGIPKP-MVILPFMKYGDLH 680
Query: 712 AFLR----EREDQLVPGQ-LVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVS 766
+L E + +P Q L+ + IA GM YLSN N++HRDLAARN ++ ++ V+
Sbjct: 681 TYLLYSRLETGPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVA 740
Query: 767 DFGLTRLLDDFDGTYETQG--GKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGD 824
DFGL++ + + G Y QG K+P++W A E++A R++T+ SDVW+FG+ MWE+ + G
Sbjct: 741 DFGLSKKI--YSGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGM 798
Query: 825 KPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLL 884
PY + N E+ + G+RL P DC LYE+M +CW D RP F L+ LE+LL
Sbjct: 799 TPYPGVQNHEMYDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKLL 858
Query: 885 ANPHSLRTIANFDPRMTLRLPSLSGSDGI 913
SL + N + + L S+G+
Sbjct: 859 ---ESLPDVRNQADVIYVNTQLLESSEGL 884
>gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]
Length = 537
Score = 213 bits (541), Expect = 9e-55
Identities = 116/253 (45%), Positives = 164/253 (64%), Gaps = 9/253 (3%)
Query: 630 IGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLE 689
+G G+FGEV+ GT ++ VAIKTLK + + +FL EA IM + H ++ L
Sbjct: 277 LGNGQFGEVWMGTWNGNTK----VAIKTLKPGTMSPE--SFLEEAQIMKKLKHDKLVQLY 330
Query: 690 GVVTKRKPIMIITEFMENGALDAFLREREDQLVP-GQLVAMLQGIASGMNYLSNHNYVHR 748
VV++ +PI I+TE+M G+L FL++ E + + LV M +A+GM Y+ NY+HR
Sbjct: 331 AVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 389
Query: 749 DLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASD 808
DL + NILV L CK++DFGL RL++D + T QG K PI+WTAPEA + FT SD
Sbjct: 390 DLRSANILVGNGLICKIADFGLARLIEDNEYTAR-QGAKFPIKWTAPEAALYGRFTIKSD 448
Query: 809 VWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRA 868
VWSFGI++ E+++ G PY M+N+EV++ +E GYR+P P DCP L+ELM +CW D
Sbjct: 449 VWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPE 508
Query: 869 RRPHFQKLQAHLE 881
RP F+ LQ+ LE
Sbjct: 509 ERPTFEYLQSFLE 521
>gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]
Length = 543
Score = 213 bits (541), Expect = 9e-55
Identities = 125/274 (45%), Positives = 169/274 (61%), Gaps = 11/274 (4%)
Query: 610 QGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWN 669
QG E+ L ++ +G+G FGEV+ GT ++ VAIKTLK PG
Sbjct: 263 QGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK----VAIKTLK---PGTMMPE 315
Query: 670 -FLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQLVP-GQLV 727
FL+EA IM + H ++ L VV++ +PI I+TEFM G+L FL+E + + + QLV
Sbjct: 316 AFLQEAQIMKKLRHDKLVPLYAVVSE-EPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLV 374
Query: 728 AMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGGK 787
M IA GM Y+ NY+HRDL A NILV +NL CK++DFGL RL++D + T QG K
Sbjct: 375 DMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTAR-QGAK 433
Query: 788 IPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPP 847
PI+WTAPEA + FT SDVWSFGI+ E+++ G PY M N+EV++ +E GYR+P
Sbjct: 434 FPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPC 493
Query: 848 PVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLE 881
P CP L+ELM CW D RP F+ +Q+ LE
Sbjct: 494 PQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 527
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,754,471
Number of Sequences: 37866
Number of extensions: 2278747
Number of successful extensions: 9717
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 586
Number of HSP's successfully gapped in prelim test: 349
Number of HSP's that attempted gapping in prelim test: 6729
Number of HSP's gapped (non-prelim): 2078
length of query: 976
length of database: 18,247,518
effective HSP length: 112
effective length of query: 864
effective length of database: 14,006,526
effective search space: 12101638464
effective search space used: 12101638464
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.