Guide to the Human Genome
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Search of human proteins with 221316586

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|221316586 BSD domain containing 1 isoform d [Homo sapiens]
         (335 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|221316586 BSD domain containing 1 isoform d [Homo sapiens]         683   0.0  
gi|221316584 BSD domain containing 1 isoform c [Homo sapiens]         664   0.0  
gi|221316581 BSD domain containing 1 isoform a [Homo sapiens]         632   0.0  
gi|221316578 BSD domain containing 1 isoform b [Homo sapiens]         632   0.0  
gi|163965366 nascent polypeptide-associated complex alpha subuni...    49   8e-06
gi|110349719 titin isoform N2-A [Homo sapiens]                         47   2e-05
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       44   3e-04
gi|74136549 AT rich interactive domain 5B (MRF1-like) [Homo sapi...    40   0.003
gi|55749621 pleckstrin homology domain containing, family G, mem...    40   0.003
gi|38372931 brevican isoform 2 [Homo sapiens]                          39   0.005
gi|38372935 brevican isoform 1 [Homo sapiens]                          39   0.005
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    39   0.007
gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo ...    39   0.007
gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo ...    39   0.007
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           39   0.009
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           39   0.009
gi|134031945 SCO-spondin [Homo sapiens]                                39   0.009
gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi...    38   0.011
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   38   0.011
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   38   0.011
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   38   0.011
gi|33286444 mastermind-like 2 [Homo sapiens]                           38   0.011
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    38   0.011
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    38   0.015
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]      38   0.015
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]       38   0.015
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]      37   0.019
gi|40807452 peroxisome proliferator-activated receptor gamma, co...    37   0.025
gi|154800453 tastin isoform 1 [Homo sapiens]                           37   0.025
gi|4502483 Ras association (RalGDS/AF-6) domain family (N-termin...    37   0.032

>gi|221316586 BSD domain containing 1 isoform d [Homo sapiens]
          Length = 335

 Score =  683 bits (1762), Expect = 0.0
 Identities = 335/335 (100%), Positives = 335/335 (100%)

Query: 1   MAEGEDVGWWRSWLQQSYQAVKEKARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEK 60
           MAEGEDVGWWRSWLQQSYQAVKEKARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEK
Sbjct: 1   MAEGEDVGWWRSWLQQSYQAVKEKARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEK 60

Query: 61  KGEISELLVGSPSIRALYTKMVPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSI 120
           KGEISELLVGSPSIRALYTKMVPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSI
Sbjct: 61  KGEISELLVGSPSIRALYTKMVPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSI 120

Query: 121 SEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVT 180
           SEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVT
Sbjct: 121 SEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVT 180

Query: 181 PSESSESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSK 240
           PSESSESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSK
Sbjct: 181 PSESSESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSK 240

Query: 241 PLTPAGHTGGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDW 300
           PLTPAGHTGGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDW
Sbjct: 241 PLTPAGHTGGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDW 300

Query: 301 EKDFDLDMTEEEVQMALSKVDASGELEDVEWEDWE 335
           EKDFDLDMTEEEVQMALSKVDASGELEDVEWEDWE
Sbjct: 301 EKDFDLDMTEEEVQMALSKVDASGELEDVEWEDWE 335


>gi|221316584 BSD domain containing 1 isoform c [Homo sapiens]
          Length = 374

 Score =  664 bits (1712), Expect = 0.0
 Identities = 335/374 (89%), Positives = 335/374 (89%), Gaps = 39/374 (10%)

Query: 1   MAEGEDVGWWRSWLQQSYQAVKEK------------------------------------ 24
           MAEGEDVGWWRSWLQQSYQAVKEK                                    
Sbjct: 1   MAEGEDVGWWRSWLQQSYQAVKEKSSEALEFMKRDLTEFTQVVQHDTACTIAATASVVKE 60

Query: 25  ---ARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKM 81
              ARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKM
Sbjct: 61  KLAARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKM 120

Query: 82  VPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISP 141
           VPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISP
Sbjct: 121 VPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISP 180

Query: 142 KEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAP 201
           KEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAP
Sbjct: 181 KEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAP 240

Query: 202 EARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVET 261
           EARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVET
Sbjct: 241 EARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVET 300

Query: 262 LREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVD 321
           LREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVD
Sbjct: 301 LREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVD 360

Query: 322 ASGELEDVEWEDWE 335
           ASGELEDVEWEDWE
Sbjct: 361 ASGELEDVEWEDWE 374


>gi|221316581 BSD domain containing 1 isoform a [Homo sapiens]
          Length = 447

 Score =  632 bits (1631), Expect = 0.0
 Identities = 312/312 (100%), Positives = 312/312 (100%)

Query: 24  KARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKMVP 83
           KARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKMVP
Sbjct: 136 KARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKMVP 195

Query: 84  AAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKE 143
           AAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKE
Sbjct: 196 AAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKE 255

Query: 144 AKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEA 203
           AKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEA
Sbjct: 256 AKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEA 315

Query: 204 RVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLR 263
           RVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLR
Sbjct: 316 RVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLR 375

Query: 264 EEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDAS 323
           EEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDAS
Sbjct: 376 EEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDAS 435

Query: 324 GELEDVEWEDWE 335
           GELEDVEWEDWE
Sbjct: 436 GELEDVEWEDWE 447



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 24/25 (96%), Positives = 25/25 (100%)

Query: 1  MAEGEDVGWWRSWLQQSYQAVKEKA 25
          MAEGEDVGWWRSWLQQSYQAVKEK+
Sbjct: 1  MAEGEDVGWWRSWLQQSYQAVKEKS 25


>gi|221316578 BSD domain containing 1 isoform b [Homo sapiens]
          Length = 430

 Score =  632 bits (1631), Expect = 0.0
 Identities = 312/312 (100%), Positives = 312/312 (100%)

Query: 24  KARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKMVP 83
           KARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKMVP
Sbjct: 119 KARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKMVP 178

Query: 84  AAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKE 143
           AAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKE
Sbjct: 179 AAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKE 238

Query: 144 AKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEA 203
           AKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEA
Sbjct: 239 AKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEA 298

Query: 204 RVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLR 263
           RVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLR
Sbjct: 299 RVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLR 358

Query: 264 EEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDAS 323
           EEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDAS
Sbjct: 359 EEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDAS 418

Query: 324 GELEDVEWEDWE 335
           GELEDVEWEDWE
Sbjct: 419 GELEDVEWEDWE 430



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 24/25 (96%), Positives = 25/25 (100%)

Query: 1  MAEGEDVGWWRSWLQQSYQAVKEKA 25
          MAEGEDVGWWRSWLQQSYQAVKEK+
Sbjct: 1  MAEGEDVGWWRSWLQQSYQAVKEKS 25


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 48/173 (27%), Positives = 77/173 (44%), Gaps = 21/173 (12%)

Query: 133  LMGISPISPKEAKVPV-AKISTFPEGEPGPQSPCEENLVTSVEP--PAEV--TPSESSES 187
            L  ++P SPKE   P     S+ P+  P   +P     + +V P  P EV  TPS   + 
Sbjct: 1467 LPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDP 1526

Query: 188  ISLVTQIAN---PAT-APEARVLPKDLS----QKLLEASLEEQGLAVDVGETGPSPPIHS 239
            I+    + +   PAT AP+  ++P  ++    +K       ++  A    +   SPP   
Sbjct: 1527 IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA-- 1584

Query: 240  KPLTPAGHTGGPEPR----PPARVETLREEAPTDLRVFELNSDSGKSTPSNNG 288
              +TP+ + G P P+    PPA      +EAPT   V   + + G +TP+  G
Sbjct: 1585 --VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKG 1635



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 36/128 (28%), Positives = 48/128 (37%), Gaps = 11/128 (8%)

Query: 140  SPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPA-----EVTPSESSESISLVTQI 194
            SPK A  P A     P+G P   SP       +V PP+       TP     S       
Sbjct: 981  SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP 1040

Query: 195  ANPATAPEARVLPKDL-SQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEP 253
             +P  +P A  LPK   +         + G A    +  P+PP  + P +P G    P P
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP-SPKGGPATPSP 1099

Query: 254  R----PPA 257
            +    PPA
Sbjct: 1100 KGAPMPPA 1107



 Score = 36.6 bits (83), Expect = 0.032
 Identities = 44/156 (28%), Positives = 60/156 (38%), Gaps = 25/156 (16%)

Query: 135  GISPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQI 194
            G++  SPK A  P    +T P  + GP +P  +   T   PPA   PS       L T  
Sbjct: 1231 GLATPSPKGA--PTTPAATPPSPKGGPATPPPKGAPT---PPAATPPSLKG---GLATPP 1282

Query: 195  ANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPR 254
               A  P     P             + G A    +  P+PP  + P +P G  G P P+
Sbjct: 1283 HKGAPNPAVVTPPS-----------PKGGPATSPPKGAPTPPAATPP-SPKGSPGTPPPK 1330

Query: 255  ----PPARVETLREEAPTDLRVFELNSDSGKSTPSN 286
                PPA      +  PT L     +S  G +TPS+
Sbjct: 1331 GAPTPPAVTPPSPKGTPT-LPATTPSSKGGPTTPSS 1365



 Score = 35.8 bits (81), Expect = 0.055
 Identities = 43/163 (26%), Positives = 58/163 (35%), Gaps = 40/163 (24%)

Query: 141  PKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATA 200
            PK A  P A     P+G PG   P           P  VTP     + +L      PAT 
Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPPP------KGAPTPPAVTPPSPKGTPTL------PATT 1353

Query: 201  PEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVE 260
            P ++  P   S K                  GP+PP      TP+ H GGP   PP+   
Sbjct: 1354 PSSKGGPTTPSSK-----------------EGPTPP----AATPS-HKGGPAMTPPSPKR 1391

Query: 261  ----TLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISED 299
                   +  PT   V  L+     +TP    ++G++T    D
Sbjct: 1392 GPAIPSPKGDPTSPAVIPLSPKKAPATPVT--REGAATPSKGD 1432



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 43/159 (27%), Positives = 58/159 (36%), Gaps = 15/159 (9%)

Query: 137  SPISPKEAKVPVAKISTFPEGEPGP----QSPCEENLVTSVEPPAEVTPSESSESISLVT 192
            +P SPK A  P A     P+G   P     +P   NL    E PA   P + + ++S+ +
Sbjct: 857  TPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ-APALSMTS 915

Query: 193  QIANPATA-PEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKP--LTPAGHTG 249
                 A A P  + +P   S K           +   G   PSP     P   TP    G
Sbjct: 916  SSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKG 975

Query: 250  GPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNG 288
            GP    P       + APT       +   G +TPS  G
Sbjct: 976  GPATPSP-------KGAPTPPAATPPSPKGGPATPSPKG 1007



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 41/143 (28%), Positives = 58/143 (40%), Gaps = 22/143 (15%)

Query: 140  SPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIA--NP 197
            SPKEA  P A   T P  E GP +P  +   TS  PP  VTPS   +S +    +     
Sbjct: 1609 SPKEAPTPPAV--TPPSPEKGPATPAPKGTPTS--PP--VTPSSLKDSPTSPASVTCKMG 1662

Query: 198  ATAPE------ARVLPKDLSQKLLEASLEEQGLAVDVGETGP--------SPPIHSKPLT 243
            AT P+      A+  P  L + L+  + E   +       GP        SPPI   P  
Sbjct: 1663 ATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSA 1722

Query: 244  PAGHTGGPEPRPPARVETLREEA 266
              G  G      PA +  +++++
Sbjct: 1723 KNGSKGPLSTVAPAPLLPVQKDS 1745



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 44/156 (28%), Positives = 52/156 (33%), Gaps = 19/156 (12%)

Query: 140  SPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPAT 199
            SPK A  P A     P+G P   SP       +  PPA   PS         T     A 
Sbjct: 935  SPKGAPTPPAATPPSPKGGPATPSP-----KWAPTPPAATPPSPKG---GPATPSPKGAP 986

Query: 200  APEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSP-------PIHSKPLTPAGHTGGPE 252
             P A   P   S K   A+   +G       T PSP       P      TP   T  P 
Sbjct: 987  TPPAATPP---SPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT-PPS 1042

Query: 253  PRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNG 288
            P+       L + APT       +   G +TPS  G
Sbjct: 1043 PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG 1078



 Score = 33.1 bits (74), Expect = 0.36
 Identities = 29/91 (31%), Positives = 41/91 (45%), Gaps = 8/91 (8%)

Query: 147 PVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVT---QIANPATAPEA 203
           P  K +T       PQ+P   +L   V PPA +  S S++S+ +VT   + A P T P+ 
Sbjct: 244 PQVKDTTISSVLISPQNPGSLSLKGPVSPPAAL--SLSTQSLPVVTSSQKTAGPNTPPD- 300

Query: 204 RVLPKDLSQKLLEASLEEQGLAVDVGETGPS 234
              P  L   L        G    +G+TGPS
Sbjct: 301 --FPISLGSHLAPLHQSSFGSVQLLGQTGPS 329


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 54/197 (27%), Positives = 82/197 (41%), Gaps = 22/197 (11%)

Query: 103   EQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQ 162
             E+E    + +    E    EE    EEEE L     + P+E ++P  +    PE E  P+
Sbjct: 10104 EEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPE 10163

Query: 163   SP---CEENLVTSVEPPAEVTPSESSESISLVTQ----IANPATAPEARV--LPKDLSQK 213
                   EE ++  V+P   V P+   E    VT+    I     AP A+V  +PK + +K
Sbjct: 10164 EEEFVPEEEVLPEVKPKVPV-PAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEK 10222

Query: 214   LLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLREEAPTDLRVF 273
              +    EE+ L V+V E     PI  + +          P  P  +E + E AP   RV 
Sbjct: 10223 RIILPKEEEVLPVEVTEEPEEEPISEEEI----------PEEPPSIEEVEEVAPP--RVP 10270

Query: 274   ELNSDSGKSTPSNNGKK 290
             E+   +    P+   KK
Sbjct: 10271 EVIKKAVPEAPTPVPKK 10287



 Score = 33.1 bits (74), Expect = 0.36
 Identities = 49/197 (24%), Positives = 72/197 (36%), Gaps = 31/197 (15%)

Query: 98    KVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGIS-PISPK----EAKVPVAKIS 152
             +V++  +E A  + +    E+ +   P  EEEE E+   + P  PK    E KVPV K  
Sbjct: 10802 EVYEEPEEIAPEEEIAPEEEKPV---PVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKP 10858

Query: 153   TFPEG-EPGPQSPCEE-NLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKDL 210
               P   EP P+   E+  L     PP    P E  +      +       PE   +P+ +
Sbjct: 10859 EAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKV 10918

Query: 211   SQKLLEASLEEQGLAVDVGETGPSPP-------------------IHSKPLTPAGHTGGP 251
                 L+    E+ +   + E  P P                    +  K L        P
Sbjct: 10919 ELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVP 10978

Query: 252   EPRPPARVETLREEAPT 268
             EP PP  VE +  E PT
Sbjct: 10979 EPPPPKPVEEV--EVPT 10993



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 42/162 (25%), Positives = 62/162 (38%), Gaps = 23/162 (14%)

Query: 117   EQSISEEPGWEEEEEELMGISPISPKEAK-VPVAKISTFPEGEP-----GPQSPCEENLV 170
             E++ S  P   EE EE+     I+P+E K VPVA+    PE  P      P+    E  V
Sbjct: 10794 ERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAE-EEEPEVPPPAVPEEPKKIIPEKKV 10852

Query: 171   TSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPK-DLSQKLLEASLEEQGLAVDVG 229
               ++ P    P E      +      P   P     PK D+ +K+ +        A+   
Sbjct: 10853 PVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLK------AIPKK 10906

Query: 230   ETGPSPPIHSK-PLTPAGHTGG--------PEPRPPARVETL 262
             +    P +  K  LTP    GG        PE +P  + E +
Sbjct: 10907 KVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVV 10948


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 51/192 (26%), Positives = 76/192 (39%), Gaps = 32/192 (16%)

Query: 116 AEQSISEEPGWEEE---EEELMGISPISPKEA-------------------KVPVAKIST 153
           AE ++ E P   E    EE L  + P+ P+EA                   + P    S 
Sbjct: 401 AEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSP 460

Query: 154 FPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKDLSQK 213
            P+     ++  E  L+ + EPPA+ TP+E+   +S  T  A  A A     L ++ + +
Sbjct: 461 LPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETS-AEEAHAEVQSPLAEETTAE 519

Query: 214 LLEASLEEQGLAVDVGETGPSPPIHSKPLT--PAGHTGGPEPRPPARVETLREEAPTDLR 271
             EAS E Q LA        +P     PL+   +      E + P+      EEAP    
Sbjct: 520 --EASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAP---- 573

Query: 272 VFELNSDSGKST 283
             EL   SG+ T
Sbjct: 574 -LELQPPSGEET 584



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 73/323 (22%), Positives = 116/323 (35%), Gaps = 52/323 (16%)

Query: 34  PATYCNEPDGPPELFDAWLSQFCLEEKKG-------EISELLVGSPSIRALYTKMVPAAV 86
           PAT  NE  G   +     + F  E KKG       E+ E +           K V +A 
Sbjct: 200 PATNSNEEIGQKNISR---TSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAE 256

Query: 87  SHSEFWHRYFYKVHQLEQEQARRDALKQRAEQS-ISEEPGWEE--EEEELMGISPISPKE 143
                  ++  K+     E+A   A  + AE++ +  +P  EE  + E    ++  S K 
Sbjct: 257 IEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKV 316

Query: 144 AKVPV--AKISTFPEGEPGP---QSPCEENLVTSVEPPAEVTPS------------ESSE 186
              P   A +  FP     P   +SP  E L   + P AE +PS            E S 
Sbjct: 317 QPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSP 376

Query: 187 SISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVD--------------VGETG 232
           S+ L+ +I +P+    A+  P ++     E +LEE    V+              + E  
Sbjct: 377 SVELLGEIRSPS----AQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEA 432

Query: 233 PSPPIHSKPLTPAGHTGGPEP----RPPARVETLREEAPTDLRVFELNSDSGKSTPSNNG 288
           P        L+ A  T   E     + P   ET  EEA  ++++          TP+   
Sbjct: 433 PREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEAR 492

Query: 289 KKGSSTDISEDWEKDFDLDMTEE 311
              S    +E+   +    + EE
Sbjct: 493 SPLSEETSAEEAHAEVQSPLAEE 515



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 53/229 (23%), Positives = 80/229 (34%), Gaps = 27/229 (11%)

Query: 58  EEKKGEISELLVGSPSIRALYTKMVPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAE 117
           EE   E +   V SPS + +  +  P  +           +     Q  A  +A  + A 
Sbjct: 548 EETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAP 607

Query: 118 QSISEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPA 177
             +   P  E   E    + P   +EA   V       +  P  ++P E     + E PA
Sbjct: 608 AEVQPPPAEEAPAE----VQPPPAEEAPAEV-------QPPPAEEAPAEVQPPPAEEAPA 656

Query: 178 EVTPSESSESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPI 237
           EV P  + E+ + V          E + LP +      E  +EE   AV       SPP 
Sbjct: 657 EVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAE------ETPIEETLAAVH------SPPA 704

Query: 238 HSKPLTPAGHTGGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSN 286
                 PA      +  PPA +  L EE P      E++    + TP +
Sbjct: 705 DD---VPAEEASVDKHSPPADL-LLTEEFPIGEASAEVSPPPSEQTPED 749



 Score = 30.0 bits (66), Expect = 3.0
 Identities = 36/149 (24%), Positives = 59/149 (39%), Gaps = 21/149 (14%)

Query: 105 EQARRDALKQRAEQSISE--EPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQ 162
           E+A  +     AE++ +E   P  EE   E      + P  A+   A++ + P  E    
Sbjct: 640 EEAPAEVQPPPAEEAPAEVQPPPAEEAPAE------VQPPPAEEAPAEVQSLPAEE---- 689

Query: 163 SPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLP-----KDLSQKLLEA 217
           +P EE L     PPA+  P+E +     V + + PA        P      ++S    E 
Sbjct: 690 TPIEETLAAVHSPPADDVPAEEAS----VDKHSPPADLLLTEEFPIGEASAEVSPPPSEQ 745

Query: 218 SLEEQGLAVDVGETGPSPPIHSKPLTPAG 246
           + E++ L  +V     SP +   P    G
Sbjct: 746 TPEDEALVENVSTEFQSPQVAGIPAVKLG 774


>gi|74136549 AT rich interactive domain 5B (MRF1-like) [Homo
           sapiens]
          Length = 1188

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 24/128 (18%)

Query: 161 PQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPK-----DLSQKLL 215
           P+S  E+      +  AEV+  +  E  +L++Q + P   P A +  K     + S K L
Sbjct: 449 PKSKKEKENAPKPQDAAEVSSEQEKEQETLISQKSIPEPLPAADMKKKIEGYQEFSAKPL 508

Query: 216 EASLE-------EQG-----LAVDVGETGPSPPIHSKPLTP-------AGHTGGPEPRPP 256
            + ++       +QG     +A + GE GP+PP+ S PL P        G +  P   P 
Sbjct: 509 ASRVDPEKDNETDQGSNSEKVAEEAGEKGPTPPLPSAPLAPEKDSALVPGASKQPLTSPS 568

Query: 257 ARVETLRE 264
           A V++ +E
Sbjct: 569 ALVDSKQE 576


>gi|55749621 pleckstrin homology domain containing, family G, member
           3 [Homo sapiens]
          Length = 1163

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 8/98 (8%)

Query: 100 HQLEQ--EQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEG 157
           H L Q  E+AR   +K +  +    E           G SP S  E ++    IS+ PE 
Sbjct: 397 HLLRQLNEKARAAGMKGKGRR----ESESSRSSRRPSGRSPTST-EKRMSFESISSLPEV 451

Query: 158 EPGPQSPCEENLVTSVE-PPAEVTPSESSESISLVTQI 194
           EP P++  E+ + ++VE P AE TPS++     L TQ+
Sbjct: 452 EPDPEAGSEQEVFSAVEGPSAEETPSDTESPEVLETQL 489


>gi|38372931 brevican isoform 2 [Homo sapiens]
          Length = 671

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 49/185 (26%), Positives = 71/185 (38%), Gaps = 13/185 (7%)

Query: 103 EQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQ 162
           E+ +A  +  K   E+   EE   EE E+E +   P S   +  P A + T P  +    
Sbjct: 448 EEGKALEEEEKYEDEEEKEEEEEEEEVEDEALWAWP-SELSSPGPEASLPTEPAAQEESL 506

Query: 163 SPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQ 222
           S      V  ++P A   P   SE+ S   ++  P T      LP    + L   S    
Sbjct: 507 SQAPARAV--LQPGASPLPDGESEA-SRPPRVHGPPT----ETLPTPRERNLASPSPSTL 559

Query: 223 GLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLREEAPTDLRVFELNSD--SG 280
             A +VGE    P +   P   +  TG  E  P     T    AP   R  E  S+  SG
Sbjct: 560 VEAREVGEATGGPELSGVPRGESEETGSSEGAPSLLPAT---RAPEGTRELEAPSEDNSG 616

Query: 281 KSTPS 285
           ++ P+
Sbjct: 617 RTAPA 621



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 33/127 (25%), Positives = 57/127 (44%), Gaps = 12/127 (9%)

Query: 189 SLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHT 248
           S + + +NPA+ P +  L   ++   +  +LEE  L  +  E+     I+S P+   G  
Sbjct: 360 SAIPEASNPASNPASDGLEAIVT---VTETLEELQLPQEATESESRGAIYSIPIMEDGGG 416

Query: 249 GGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDM 308
           G   P  PA       EAP  L  FE  S    +  S   ++G + +  E +E + + + 
Sbjct: 417 GSSTPEDPA-------EAPRTLLEFETQSMVPPTGFSE--EEGKALEEEEKYEDEEEKEE 467

Query: 309 TEEEVQM 315
            EEE ++
Sbjct: 468 EEEEEEV 474


>gi|38372935 brevican isoform 1 [Homo sapiens]
          Length = 911

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 49/185 (26%), Positives = 71/185 (38%), Gaps = 13/185 (7%)

Query: 103 EQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQ 162
           E+ +A  +  K   E+   EE   EE E+E +   P S   +  P A + T P  +    
Sbjct: 448 EEGKALEEEEKYEDEEEKEEEEEEEEVEDEALWAWP-SELSSPGPEASLPTEPAAQEESL 506

Query: 163 SPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQ 222
           S      V  ++P A   P   SE+ S   ++  P T      LP    + L   S    
Sbjct: 507 SQAPARAV--LQPGASPLPDGESEA-SRPPRVHGPPT----ETLPTPRERNLASPSPSTL 559

Query: 223 GLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLREEAPTDLRVFELNSD--SG 280
             A +VGE    P +   P   +  TG  E  P     T    AP   R  E  S+  SG
Sbjct: 560 VEAREVGEATGGPELSGVPRGESEETGSSEGAPSLLPAT---RAPEGTRELEAPSEDNSG 616

Query: 281 KSTPS 285
           ++ P+
Sbjct: 617 RTAPA 621



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 33/127 (25%), Positives = 57/127 (44%), Gaps = 12/127 (9%)

Query: 189 SLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHT 248
           S + + +NPA+ P +  L   ++   +  +LEE  L  +  E+     I+S P+   G  
Sbjct: 360 SAIPEASNPASNPASDGLEAIVT---VTETLEELQLPQEATESESRGAIYSIPIMEDGGG 416

Query: 249 GGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDM 308
           G   P  PA       EAP  L  FE  S    +  S   ++G + +  E +E + + + 
Sbjct: 417 GSSTPEDPA-------EAPRTLLEFETQSMVPPTGFSE--EEGKALEEEEKYEDEEEKEE 467

Query: 309 TEEEVQM 315
            EEE ++
Sbjct: 468 EEEEEEV 474


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 50/223 (22%), Positives = 84/223 (37%), Gaps = 44/223 (19%)

Query: 96   FYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPI----SPKEAKVPVAKI 151
            +++  + E+E+   +  ++  E    EE   EEEEEEL  +  +    +  E +      
Sbjct: 920  YFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPP 979

Query: 152  STFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKDLS 211
             T P   P P+SP        V+P  E  P        L+ ++  P T  E      D +
Sbjct: 980  PTLPPALPPPESP------PKVQPEPEPEP-------GLLLEVEEPGTEEERGA---DTA 1023

Query: 212  QKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLREEAPTDLR 271
              L   +L  QG   +V   G SP              GP P+     E + EE      
Sbjct: 1024 PTLAPEALPSQG---EVEREGESP------------AAGPPPQ-----ELVEEEPSAPPT 1063

Query: 272  VFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQ 314
            + E  ++ G    S+  +    T   E+ E + + +  +E+ Q
Sbjct: 1064 LLEEETEDG----SDKVQPPPETPAEEEMETETEAEALQEKEQ 1102



 Score = 32.7 bits (73), Expect = 0.47
 Identities = 51/220 (23%), Positives = 75/220 (34%), Gaps = 49/220 (22%)

Query: 155 PEGEPGPQSPCEENLVTSVEPPAEV-------------TPSESSESISLVTQIANP---- 197
           P G P P  P +E     V  PA V               S+S +S+ +V +   P    
Sbjct: 742 PSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPP 801

Query: 198 ----ATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPP----------IHSKPLT 243
               AT P         +   + A  E + L    G   P PP          +    L 
Sbjct: 802 PPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLV 861

Query: 244 PAGHTGGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDW--- 300
           P G  GG  P  PA  E        DL V  +NS   +       ++    +  E+    
Sbjct: 862 PEGTPGGGGP--PALEE--------DLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFE 911

Query: 301 -----EKDFDLDMTEEEVQMALSKVDASGELEDVEWEDWE 335
                E+++  +  EEE +      +  GELE+ E E+ E
Sbjct: 912 EEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDE 951


>gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo
           sapiens]
          Length = 788

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 52/186 (27%), Positives = 77/186 (41%), Gaps = 35/186 (18%)

Query: 103 EQEQARRDALKQRAEQSISEEPGWEEEE--EELMGISPISPKEAKVPVAKI--------- 151
           E+E+A++   K  A+    +E   E E+   E M IS    K A+ P  K+         
Sbjct: 153 EKEEAKKTEDKSLAKPETDKEQDSEMEKGGREDMDIS----KSAEEPQEKVDLTLDWLTE 208

Query: 152 -STFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVT----------QIANPATA 200
            S   +G   P+ P E   VTS +P  EV  +E  +S+S             Q       
Sbjct: 209 TSEEAKGGAAPEGPNEAE-VTSGKPEQEVPDAEEEKSVSGTDVQEECREKGGQEKQGEVI 267

Query: 201 PEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVE 260
                 PK++S++    +LE+QG AV+V      P +  KP+      GG EP    +V 
Sbjct: 268 VSIEEKPKEVSEEQPVVTLEKQGTAVEVEAESLDPTV--KPV----DVGGDEPE--EKVV 319

Query: 261 TLREEA 266
           T   EA
Sbjct: 320 TSENEA 325


>gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo
           sapiens]
          Length = 790

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 52/186 (27%), Positives = 77/186 (41%), Gaps = 35/186 (18%)

Query: 103 EQEQARRDALKQRAEQSISEEPGWEEEE--EELMGISPISPKEAKVPVAKI--------- 151
           E+E+A++   K  A+    +E   E E+   E M IS    K A+ P  K+         
Sbjct: 155 EKEEAKKTEDKSLAKPETDKEQDSEMEKGGREDMDIS----KSAEEPQEKVDLTLDWLTE 210

Query: 152 -STFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVT----------QIANPATA 200
            S   +G   P+ P E   VTS +P  EV  +E  +S+S             Q       
Sbjct: 211 TSEEAKGGAAPEGPNEAE-VTSGKPEQEVPDAEEEKSVSGTDVQEECREKGGQEKQGEVI 269

Query: 201 PEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVE 260
                 PK++S++    +LE+QG AV+V      P +  KP+      GG EP    +V 
Sbjct: 270 VSIEEKPKEVSEEQPVVTLEKQGTAVEVEAESLDPTV--KPV----DVGGDEPE--EKVV 321

Query: 261 TLREEA 266
           T   EA
Sbjct: 322 TSENEA 327


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 36/117 (30%), Positives = 50/117 (42%), Gaps = 8/117 (6%)

Query: 131  EELMGISPISPKEAKVPVAKISTFPEGEP--GPQSPCEENLVTSVEP-PAEVTPSESSES 187
            EE   + P+ P+E  +        P  EP  GP  P E++ +T+    P EV  S S ES
Sbjct: 1152 EEPPTMPPLPPEEPPMT----PPLPPEEPPEGPALPTEQSALTAENTWPTEVPSSPSEES 1207

Query: 188  ISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTP 244
            +S      + +   E   +P D S    + S+     AV V E  P P   S  LTP
Sbjct: 1208 VSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPEPE-SSITLTP 1263



 Score = 30.0 bits (66), Expect = 3.0
 Identities = 24/88 (27%), Positives = 33/88 (37%), Gaps = 6/88 (6%)

Query: 121  SEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVT 180
            +E P    EE       P+S  E   P A  + +      P     E  VT  EPP E  
Sbjct: 1197 TEVPSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPE-- 1254

Query: 181  PSESSESISLVTQIANPATAPEARVLPK 208
                 ES   +T + +   A E  V+P+
Sbjct: 1255 ----PESSITLTPVESAVVAEEHEVVPE 1278



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 31/119 (26%), Positives = 42/119 (35%), Gaps = 17/119 (14%)

Query: 138 PISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTP----SESSESISLVTQ 193
           P  P  +  PV ++S    G P P           +EPP EV      ++    + LVT 
Sbjct: 436 PELPGPSVTPVPQLSQELPGLPAPSM--------GLEPPQEVPEPPVMAQELPGLPLVTA 487

Query: 194 IANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPE 252
                  P   V  +   Q +    LE+      VG T    P H +  T  G  G PE
Sbjct: 488 AVELPEQPAVTVAMELTEQPVTTTELEQP-----VGMTTVEHPGHPEVTTATGLLGQPE 541


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 36/117 (30%), Positives = 50/117 (42%), Gaps = 8/117 (6%)

Query: 131  EELMGISPISPKEAKVPVAKISTFPEGEP--GPQSPCEENLVTSVEP-PAEVTPSESSES 187
            EE   + P+ P+E  +        P  EP  GP  P E++ +T+    P EV  S S ES
Sbjct: 1152 EEPPTMPPLPPEEPPMT----PPLPPEEPPEGPALPTEQSALTAENTWPTEVPSSPSEES 1207

Query: 188  ISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTP 244
            +S      + +   E   +P D S    + S+     AV V E  P P   S  LTP
Sbjct: 1208 VSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPEPE-SSITLTP 1263



 Score = 30.0 bits (66), Expect = 3.0
 Identities = 24/88 (27%), Positives = 33/88 (37%), Gaps = 6/88 (6%)

Query: 121  SEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVT 180
            +E P    EE       P+S  E   P A  + +      P     E  VT  EPP E  
Sbjct: 1197 TEVPSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPE-- 1254

Query: 181  PSESSESISLVTQIANPATAPEARVLPK 208
                 ES   +T + +   A E  V+P+
Sbjct: 1255 ----PESSITLTPVESAVVAEEHEVVPE 1278



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 31/119 (26%), Positives = 42/119 (35%), Gaps = 17/119 (14%)

Query: 138 PISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTP----SESSESISLVTQ 193
           P  P  +  PV ++S    G P P           +EPP EV      ++    + LVT 
Sbjct: 436 PELPGPSVTPVPQLSQELPGLPAPSM--------GLEPPQEVPEPPVMAQELPGLPLVTA 487

Query: 194 IANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPE 252
                  P   V  +   Q +    LE+      VG T    P H +  T  G  G PE
Sbjct: 488 AVELPEQPAVTVAMELTEQPVTTTELEQP-----VGMTTVEHPGHPEVTTATGLLGQPE 541


>gi|134031945 SCO-spondin [Homo sapiens]
          Length = 5147

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 35/111 (31%), Positives = 46/111 (41%), Gaps = 23/111 (20%)

Query: 148  VAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLP 207
            +A+   +P G+  P SP E   V+    PA   P    ES+ +VT    P    EAR LP
Sbjct: 2303 LAETEHWPPGQESPTSPTETRPVSP--GPASGVPHHG-ESVQMVT--TTPIPQMEARTLP 2357

Query: 208  KDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPAR 258
              ++             AV V      PP    P TPAG +  P P PP +
Sbjct: 2358 PGMA-------------AVTV-----VPPHPVTPATPAGQSVAPGPFPPVQ 2390


>gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo
           sapiens]
          Length = 729

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 54/223 (24%), Positives = 84/223 (37%), Gaps = 33/223 (14%)

Query: 128 EEEEELM----GISPISPKEAKVPVAKISTFPEGEP----------GPQSPCEENLVT-- 171
           EEE E+     G +P +P++   P  K S+ P  +P           P  P   ++ T  
Sbjct: 472 EEEAEVAAPTKGPAP-APQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGP 530

Query: 172 ----SVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVD 227
               S  PPAE+ P +         Q ++  + PE  +  + LS  + +   E +G   D
Sbjct: 531 EKRSSTRPPAEMEPGKGE-------QASSSESDPEGPIAAQMLSFVMDDPDFESEGS--D 581

Query: 228 VGETGPSPPIHSKPLTPAGHTGGP-EPRPPARVETLREEAPTDLRVFELN-SDSGKSTPS 285
                   P+   P        GP EP PP ++         D  +F L   ++G    S
Sbjct: 582 TQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESS 641

Query: 286 NNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDASGELED 328
             GK+G  T   E  +K       EE+     SK   S + E+
Sbjct: 642 EEGKEG-KTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEE 683


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 48/193 (24%), Positives = 72/193 (37%), Gaps = 15/193 (7%)

Query: 137 SPISPKEAK--VPVAKISTFPEGEPGPQSPCEENLVTSVEP----PAEVTPSESSESISL 190
           +P +PKE     P     T P+ EP P +P E    T+ +P    P E  P+   E+   
Sbjct: 427 APTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT 485

Query: 191 VTQIANPAT----APEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAG 246
             +   P T    AP     P   + + L  +  E+       E  P+ P  + P TP  
Sbjct: 486 TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK- 544

Query: 247 HTGGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDL 306
                 P+ PA   T +E APT  +  E    + K T     K+ + T   +   K+   
Sbjct: 545 EPAPTTPKEPAPT-TPKEPAPTTPK--ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 601

Query: 307 DMTEEEVQMALSK 319
             T+E       K
Sbjct: 602 TTTKEPTSTTCDK 614



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 34/132 (25%), Positives = 48/132 (36%), Gaps = 20/132 (15%)

Query: 137 SPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIAN 196
           +P +PKE      K +     EP P         T+ + PA  TP E + +    T+   
Sbjct: 240 APTTPKEPAPTTTKSAPTTPKEPAP---------TTTKEPAPTTPKEPAPT---TTKEPA 287

Query: 197 PATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPP 256
           P T   A   PK+ +    +          +   T P  P  + P  PA  T  P P  P
Sbjct: 288 PTTTKSAPTTPKEPAPTTPKKPAPT--TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 345

Query: 257 ARVETLREEAPT 268
                 +E APT
Sbjct: 346 ------KEPAPT 351



 Score = 33.5 bits (75), Expect = 0.27
 Identities = 34/140 (24%), Positives = 52/140 (37%), Gaps = 12/140 (8%)

Query: 137 SPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEP----PAEVTPSESSESISLVT 192
           +P +PKE      + +     EP P +P +    T  EP    P E  P+ + E      
Sbjct: 326 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 385

Query: 193 QIANPATAPEARVLPKDLSQKLLEA--SLEEQGLAVDVGETGPSPPIHSKPLTP--AGHT 248
           +   P T   A    K+ +    ++  +  ++       E  P+ P    P TP     T
Sbjct: 386 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 445

Query: 249 GGPEPRPPARVETLREEAPT 268
              EP P     T +E APT
Sbjct: 446 TPKEPAP----TTPKEPAPT 461


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 48/193 (24%), Positives = 72/193 (37%), Gaps = 15/193 (7%)

Query: 137 SPISPKEAK--VPVAKISTFPEGEPGPQSPCEENLVTSVEP----PAEVTPSESSESISL 190
           +P +PKE     P     T P+ EP P +P E    T+ +P    P E  P+   E+   
Sbjct: 468 APTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT 526

Query: 191 VTQIANPAT----APEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAG 246
             +   P T    AP     P   + + L  +  E+       E  P+ P  + P TP  
Sbjct: 527 TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK- 585

Query: 247 HTGGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDL 306
                 P+ PA   T +E APT  +  E    + K T     K+ + T   +   K+   
Sbjct: 586 EPAPTTPKEPAPT-TPKEPAPTTPK--ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 642

Query: 307 DMTEEEVQMALSK 319
             T+E       K
Sbjct: 643 TTTKEPTSTTCDK 655



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 34/132 (25%), Positives = 48/132 (36%), Gaps = 20/132 (15%)

Query: 137 SPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIAN 196
           +P +PKE      K +     EP P         T+ + PA  TP E + +    T+   
Sbjct: 281 APTTPKEPAPTTTKSAPTTPKEPAP---------TTTKEPAPTTPKEPAPT---TTKEPA 328

Query: 197 PATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPP 256
           P T   A   PK+ +    +          +   T P  P  + P  PA  T  P P  P
Sbjct: 329 PTTTKSAPTTPKEPAPTTPKKPAPT--TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 386

Query: 257 ARVETLREEAPT 268
                 +E APT
Sbjct: 387 ------KEPAPT 392



 Score = 33.5 bits (75), Expect = 0.27
 Identities = 34/140 (24%), Positives = 52/140 (37%), Gaps = 12/140 (8%)

Query: 137 SPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEP----PAEVTPSESSESISLVT 192
           +P +PKE      + +     EP P +P +    T  EP    P E  P+ + E      
Sbjct: 367 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 426

Query: 193 QIANPATAPEARVLPKDLSQKLLEA--SLEEQGLAVDVGETGPSPPIHSKPLTP--AGHT 248
           +   P T   A    K+ +    ++  +  ++       E  P+ P    P TP     T
Sbjct: 427 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 486

Query: 249 GGPEPRPPARVETLREEAPT 268
              EP P     T +E APT
Sbjct: 487 TPKEPAP----TTPKEPAPT 502


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 48/193 (24%), Positives = 72/193 (37%), Gaps = 15/193 (7%)

Query: 137 SPISPKEAK--VPVAKISTFPEGEPGPQSPCEENLVTSVEP----PAEVTPSESSESISL 190
           +P +PKE     P     T P+ EP P +P E    T+ +P    P E  P+   E+   
Sbjct: 520 APTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT 578

Query: 191 VTQIANPAT----APEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAG 246
             +   P T    AP     P   + + L  +  E+       E  P+ P  + P TP  
Sbjct: 579 TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK- 637

Query: 247 HTGGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDL 306
                 P+ PA   T +E APT  +  E    + K T     K+ + T   +   K+   
Sbjct: 638 EPAPTTPKEPAPT-TPKEPAPTTPK--ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 694

Query: 307 DMTEEEVQMALSK 319
             T+E       K
Sbjct: 695 TTTKEPTSTTCDK 707



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 34/132 (25%), Positives = 48/132 (36%), Gaps = 20/132 (15%)

Query: 137 SPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIAN 196
           +P +PKE      K +     EP P         T+ + PA  TP E + +    T+   
Sbjct: 333 APTTPKEPAPTTTKSAPTTPKEPAP---------TTTKEPAPTTPKEPAPT---TTKEPA 380

Query: 197 PATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPP 256
           P T   A   PK+ +    +          +   T P  P  + P  PA  T  P P  P
Sbjct: 381 PTTTKSAPTTPKEPAPTTPKKPAPT--TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 438

Query: 257 ARVETLREEAPT 268
                 +E APT
Sbjct: 439 ------KEPAPT 444



 Score = 33.5 bits (75), Expect = 0.27
 Identities = 34/140 (24%), Positives = 52/140 (37%), Gaps = 12/140 (8%)

Query: 137 SPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEP----PAEVTPSESSESISLVT 192
           +P +PKE      + +     EP P +P +    T  EP    P E  P+ + E      
Sbjct: 419 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 478

Query: 193 QIANPATAPEARVLPKDLSQKLLEA--SLEEQGLAVDVGETGPSPPIHSKPLTP--AGHT 248
           +   P T   A    K+ +    ++  +  ++       E  P+ P    P TP     T
Sbjct: 479 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 538

Query: 249 GGPEPRPPARVETLREEAPT 268
              EP P     T +E APT
Sbjct: 539 TPKEPAP----TTPKEPAPT 554


>gi|33286444 mastermind-like 2 [Homo sapiens]
          Length = 1156

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 41/172 (23%), Positives = 71/172 (41%), Gaps = 26/172 (15%)

Query: 154  FPEGEPGPQSP---------CEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEAR 204
            FP G P   +P          ++    +V PP ++TP+     ++ ++Q  N  T    R
Sbjct: 986  FPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRPMNQMSQTLNGQTMGPLR 1045

Query: 205  VL---PKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVET 261
             L   P  LS ++L  +L + G  ++   TG + P     LTP+     P P   +R   
Sbjct: 1046 GLNLRPNQLSTQIL-PNLNQSGTGLNQSRTGINQP---PSLTPSNF---PSPNQSSRAFQ 1098

Query: 262  LREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDI------SEDWEKDFDLD 307
              + + +DL    L+  +    P+ N        +      ++DW KD +LD
Sbjct: 1099 GTDHS-SDLAFDFLSQQNDNMGPALNSDADFIDSLLKTEPGNDDWMKDINLD 1149


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 48/193 (24%), Positives = 72/193 (37%), Gaps = 15/193 (7%)

Query: 137 SPISPKEAK--VPVAKISTFPEGEPGPQSPCEENLVTSVEP----PAEVTPSESSESISL 190
           +P +PKE     P     T P+ EP P +P E    T+ +P    P E  P+   E+   
Sbjct: 561 APTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT 619

Query: 191 VTQIANPAT----APEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAG 246
             +   P T    AP     P   + + L  +  E+       E  P+ P  + P TP  
Sbjct: 620 TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK- 678

Query: 247 HTGGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDL 306
                 P+ PA   T +E APT  +  E    + K T     K+ + T   +   K+   
Sbjct: 679 EPAPTTPKEPAPT-TPKEPAPTTPK--ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 735

Query: 307 DMTEEEVQMALSK 319
             T+E       K
Sbjct: 736 TTTKEPTSTTCDK 748



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 34/132 (25%), Positives = 48/132 (36%), Gaps = 20/132 (15%)

Query: 137 SPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIAN 196
           +P +PKE      K +     EP P         T+ + PA  TP E + +    T+   
Sbjct: 374 APTTPKEPAPTTTKSAPTTPKEPAP---------TTTKEPAPTTPKEPAPT---TTKEPA 421

Query: 197 PATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPP 256
           P T   A   PK+ +    +          +   T P  P  + P  PA  T  P P  P
Sbjct: 422 PTTTKSAPTTPKEPAPTTPKKPAPT--TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 479

Query: 257 ARVETLREEAPT 268
                 +E APT
Sbjct: 480 ------KEPAPT 485



 Score = 33.5 bits (75), Expect = 0.27
 Identities = 34/140 (24%), Positives = 52/140 (37%), Gaps = 12/140 (8%)

Query: 137 SPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEP----PAEVTPSESSESISLVT 192
           +P +PKE      + +     EP P +P +    T  EP    P E  P+ + E      
Sbjct: 460 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 519

Query: 193 QIANPATAPEARVLPKDLSQKLLEA--SLEEQGLAVDVGETGPSPPIHSKPLTP--AGHT 248
           +   P T   A    K+ +    ++  +  ++       E  P+ P    P TP     T
Sbjct: 520 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 579

Query: 249 GGPEPRPPARVETLREEAPT 268
              EP P     T +E APT
Sbjct: 580 TPKEPAP----TTPKEPAPT 595


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 35/131 (26%), Positives = 48/131 (36%), Gaps = 12/131 (9%)

Query: 137 SPISPKEAKVPVAKIST-----------FPEGEPGPQSPCEENLVTSVEPPAE-VTPSES 184
           SP+SP E   P   + T            P  E  P SP  E L TS  P A  ++P   
Sbjct: 518 SPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPE 577

Query: 185 SESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTP 244
              +S   + +  +  PEA  L     +  L    EE  L+     +  SPP    P++P
Sbjct: 578 ESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSP 637

Query: 245 AGHTGGPEPRP 255
                   P P
Sbjct: 638 PPEESPMSPPP 648



 Score = 37.0 bits (84), Expect = 0.025
 Identities = 37/143 (25%), Positives = 57/143 (39%), Gaps = 12/143 (8%)

Query: 137 SPISPKEAKVPVA---KISTFPEGEPGPQSPCEEN-----LVTSVEPPAEVTPSE---SS 185
           SP+SP   + P++   + S F   E  P SP EE+     L T + PP E +P       
Sbjct: 492 SPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEE 551

Query: 186 ESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPA 245
             +S   +    +  PEA  L     +  +    EE  ++     +   PP    PL+P 
Sbjct: 552 SPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPP 611

Query: 246 GHTGGPEPRPPA-RVETLREEAP 267
                  P P A R+    E++P
Sbjct: 612 PEESPLSPPPEASRLSPPPEDSP 634



 Score = 33.5 bits (75), Expect = 0.27
 Identities = 29/121 (23%), Positives = 48/121 (39%), Gaps = 7/121 (5%)

Query: 139 ISPKEAKVPVAKISTFPEGEPGPQSPC------EENLVTSVEPPAEVTPSESSESISLVT 192
           +SP+  +  ++  +  P   P P+ PC      E +L    E P  ++P      +S  T
Sbjct: 752 LSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGP-HLSPQPEELHLSPQT 810

Query: 193 QIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPE 252
           +  + +  PE   L     +  L    EE  L+    E+  SP +   PL+P       E
Sbjct: 811 EEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEE 870

Query: 253 P 253
           P
Sbjct: 871 P 871



 Score = 32.3 bits (72), Expect = 0.61
 Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 15/109 (13%)

Query: 158 EPGPQSPCEENLV-------TSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKDL 210
           EP  ++P  E +        + + PP E +P+      S   +++ P     A  LP+ L
Sbjct: 427 EPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEAS---RLSPPPEELPASPLPEAL 483

Query: 211 SQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHT--GGPEPRPPA 257
               L   LEE  L+    E+  SPP  S P +P   +    PE  PP+
Sbjct: 484 H---LSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPS 529



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 37/147 (25%), Positives = 54/147 (36%), Gaps = 15/147 (10%)

Query: 137 SPISPKEAKVPVAK----ISTFPEGEPGPQSPCEENLVTSVEPPAE-VTPSESSESISLV 191
           SP+SP   ++P +         P  E  P SP  E    S  P A  + P      +S  
Sbjct: 552 SPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPP 611

Query: 192 TQIANPATAPEARVLPKDLSQKLLEASLEEQGLAV--DVGETGP-------SPPIHSKPL 242
            + +  +  PEA  L        +    EE  ++   +V    P       SPP    PL
Sbjct: 612 PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPL 671

Query: 243 TPAGHTGGPEPRPPA-RVETLREEAPT 268
           +P        P P A R+    E++PT
Sbjct: 672 SPPPEESPTSPPPEASRLSPPPEDSPT 698


>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
          Length = 1303

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 55/249 (22%), Positives = 85/249 (34%), Gaps = 66/249 (26%)

Query: 102 LEQEQARRDALKQRAEQSI----------------SEEPGWEEEEEELMGISPISPKEAK 145
           L+Q+Q ++   KQ+ +Q +                +++P W  E EE   ++    K+  
Sbjct: 479 LQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMN----KQQN 534

Query: 146 VPVAKIST--------FPEGEPGPQSPCEENLVTSVEPPAE--VTPSESSESISLVTQIA 195
            P+AK            P+  PGP  P  +       PP +  V P E      +  ++ 
Sbjct: 535 SPLAKSKPGSTGPEPPIPQASPGPPGPLSQT------PPMQRPVEPQEGPHKSLVAHRVP 588

Query: 196 -NPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTG----- 249
             P  AP  R      SQ L +     + LA       P P I +   TP+         
Sbjct: 589 LKPYAAPVPR------SQSLQDQPT--RNLAAFPASHDPDPAIPAPTATPSARGAVIRQN 640

Query: 250 --------GPEPRPPARVETLREEAP-----TDLRVFELNSDSGKSTPSNNGKKGSSTDI 296
                   GP P PPA V    E  P     T      LN+     +      + S+ D+
Sbjct: 641 SDPTSEGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRASNPDL 700

Query: 297 SED---WEK 302
                 WE+
Sbjct: 701 RRSDPGWER 709


>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
          Length = 1295

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 55/249 (22%), Positives = 85/249 (34%), Gaps = 66/249 (26%)

Query: 102 LEQEQARRDALKQRAEQSI----------------SEEPGWEEEEEELMGISPISPKEAK 145
           L+Q+Q ++   KQ+ +Q +                +++P W  E EE   ++    K+  
Sbjct: 479 LQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMN----KQQN 534

Query: 146 VPVAKIST--------FPEGEPGPQSPCEENLVTSVEPPAE--VTPSESSESISLVTQIA 195
            P+AK            P+  PGP  P  +       PP +  V P E      +  ++ 
Sbjct: 535 SPLAKSKPGSTGPEPPIPQASPGPPGPLSQT------PPMQRPVEPQEGPHKSLVAHRVP 588

Query: 196 -NPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTG----- 249
             P  AP  R      SQ L +     + LA       P P I +   TP+         
Sbjct: 589 LKPYAAPVPR------SQSLQDQPT--RNLAAFPASHDPDPAIPAPTATPSARGAVIRQN 640

Query: 250 --------GPEPRPPARVETLREEAP-----TDLRVFELNSDSGKSTPSNNGKKGSSTDI 296
                   GP P PPA V    E  P     T      LN+     +      + S+ D+
Sbjct: 641 SDPTSEGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRASNPDL 700

Query: 297 SED---WEK 302
                 WE+
Sbjct: 701 RRSDPGWER 709


>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
          Length = 1332

 Score = 37.4 bits (85), Expect = 0.019
 Identities = 48/206 (23%), Positives = 72/206 (34%), Gaps = 58/206 (28%)

Query: 102 LEQEQARRDALKQRAEQSI----------------SEEPGWEEEEEELMGISPISPKEAK 145
           L+Q+Q ++   KQ+ +Q +                +++P W  E EE   ++    K+  
Sbjct: 479 LQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMN----KQQN 534

Query: 146 VPVAKIST--------FPEGEPGPQSPCEENLVTSVEPPAE--VTPSESSESISLVTQIA 195
            P+AK            P+  PGP  P  +       PP +  V P E      +  ++ 
Sbjct: 535 SPLAKSKPGSTGPEPPIPQASPGPPGPLSQT------PPMQRPVEPQEGPHKSLVAHRVP 588

Query: 196 -NPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTG----- 249
             P  AP  R      SQ L +     + LA       P P I +   TP+         
Sbjct: 589 LKPYAAPVPR------SQSLQDQPT--RNLAAFPASHDPDPAIPAPTATPSARGAVIRQN 640

Query: 250 --------GPEPRPPARVETLREEAP 267
                   GP P PPA V    E  P
Sbjct: 641 SDPTSEGPGPSPNPPAWVRPDNEAPP 666


>gi|40807452 peroxisome proliferator-activated receptor gamma,
           coactivator-related 1 [Homo sapiens]
          Length = 1664

 Score = 37.0 bits (84), Expect = 0.025
 Identities = 32/120 (26%), Positives = 44/120 (36%), Gaps = 10/120 (8%)

Query: 172 SVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGET 231
           S++PP  + P       SL  +    AT  EAR  P  LS    E     Q    +  E 
Sbjct: 715 SLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLS----EYRRRRQQRQAETEER 770

Query: 232 GPSPPIHSKPLTPAGHTGGPE------PRPPARVETLREEAPTDLRVFELNSDSGKSTPS 285
            P PP    P  P   TG  +      P  PA+   L+    T L +  +      ++PS
Sbjct: 771 SPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPS 830


>gi|154800453 tastin isoform 1 [Homo sapiens]
          Length = 778

 Score = 37.0 bits (84), Expect = 0.025
 Identities = 47/144 (32%), Positives = 59/144 (40%), Gaps = 24/144 (16%)

Query: 131 EELMGISPISPKEAKVPVAKISTFPE-GEPGPQSPCEENLVTSVEPPAEVTPSESS---- 185
           EE     P  P E   P A   + PE  EP  Q   E   V    PPAE  P ES     
Sbjct: 507 EECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLE---VPEPYPPAEPRPLESCCRSE 563

Query: 186 ---ESISLVTQIANPATAPEARVLPKD----LSQKLLEASLEEQGLAVDVGETGPSPPIH 238
                 S   Q+  P   P A   P +    +  ++ E+S +EQ   ++V E  P PP  
Sbjct: 564 PEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQ---LEVPE--PCPPAE 618

Query: 239 SKPLTPA--GHTGGPEPRPPARVE 260
             PL P+  G +G P P P  RVE
Sbjct: 619 PGPLQPSTQGQSGPPGPCP--RVE 640


>gi|4502483 Ras association (RalGDS/AF-6) domain family (N-terminal)
           member 7 isoform 1 [Homo sapiens]
          Length = 373

 Score = 36.6 bits (83), Expect = 0.032
 Identities = 48/186 (25%), Positives = 74/186 (39%), Gaps = 35/186 (18%)

Query: 86  VSHSEFWHRYFYKVHQLEQE-QARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKEA 144
           + H  FW +   +    E+E QAR  AL     +  +     + +   L         EA
Sbjct: 169 LGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARAL---------EA 219

Query: 145 KVPVAKISTFPEGEPGPQSPC-------EENLVTSVEPPAEVTPSESSESISL-VTQIAN 196
           ++ +A  +      PGP SP         ++L       AEV  S +  S +L   + A 
Sbjct: 220 ELQLAAEA------PGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERAL 273

Query: 197 PATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPP 256
            A A E   L ++L Q  L+  +++ G A+      P PP   +     G  G   P PP
Sbjct: 274 QAQAQELEELNRELRQCNLQQFIQQTGAAL------PPPPRPDR-----GPPGTQGPLPP 322

Query: 257 ARVETL 262
           AR E+L
Sbjct: 323 AREESL 328


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.127    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,330,915
Number of Sequences: 37866
Number of extensions: 929851
Number of successful extensions: 5672
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 423
Number of HSP's that attempted gapping in prelim test: 5092
Number of HSP's gapped (non-prelim): 1004
length of query: 335
length of database: 18,247,518
effective HSP length: 103
effective length of query: 232
effective length of database: 14,347,320
effective search space: 3328578240
effective search space used: 3328578240
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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