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Search of human proteins with 221219056
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7
isoform 2 [Homo sapiens]
(438 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 891 0.0
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 890 0.0
gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sap... 174 1e-43
gi|201862587 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform... 92 1e-18
gi|201862518 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform... 92 1e-18
gi|56549115 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform ... 92 1e-18
gi|6631085 DnaJ (Hsp40) homolog, subfamily B, member 4 [Homo sap... 90 4e-18
gi|17388799 DnaJ (Hsp40) homolog, subfamily B, member 6 isoform ... 89 8e-18
gi|4885495 DnaJ (Hsp40) homolog, subfamily B, member 6 isoform b... 89 8e-18
gi|4504511 DnaJ (Hsp40) homolog, subfamily A, member 1 [Homo sap... 87 3e-17
gi|194328758 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform... 87 3e-17
gi|194328760 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform... 86 5e-17
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 85 1e-16
gi|47777312 DnaJ (Hsp40) homolog, subfamily B, member 3 [Homo sa... 84 2e-16
gi|23503241 DnaJ homolog, subfamily B, member 8 [Homo sapiens] 82 1e-15
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 79 6e-15
gi|194306642 DnaJ (Hsp40) homolog, subfamily B, member 12 [Homo ... 79 8e-15
gi|194306640 DnaJ (Hsp40) homolog, subfamily B, member 12 [Homo ... 79 8e-15
gi|5453690 DnaJ (Hsp40) homolog, subfamily B, member 1 [Homo sap... 77 2e-14
gi|22749377 DnaJ (Hsp40) homolog, subfamily C, member 18 [Homo s... 76 7e-14
gi|88501736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform ... 75 9e-14
gi|27151736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform ... 75 9e-14
gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens] 75 9e-14
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 75 1e-13
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 75 1e-13
gi|72534740 DnaJ (Hsp40) homolog, subfamily B, member 14 isoform... 75 1e-13
gi|21553335 DnaJ (Hsp40) homolog, subfamily B, member 7 [Homo sa... 74 2e-13
gi|7706495 DnaJ (Hsp40) homolog, subfamily B, member 11 precurso... 74 3e-13
gi|54607135 translocase of outer mitochondrial membrane 70 homol... 73 6e-13
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 71 2e-12
>gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2
[Homo sapiens]
Length = 438
Score = 891 bits (2303), Expect = 0.0
Identities = 438/438 (100%), Positives = 438/438 (100%)
Query: 1 MCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAAC 60
MCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAAC
Sbjct: 1 MCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAAC 60
Query: 61 RSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACH 120
RSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACH
Sbjct: 61 RSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACH 120
Query: 121 RFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQA 180
RFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQA
Sbjct: 121 RFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQA 180
Query: 181 LRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKL 240
LRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKL
Sbjct: 181 LRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKL 240
Query: 241 YCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ 300
YCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ
Sbjct: 241 YCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ 300
Query: 301 TEKTKEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGA 360
TEKTKEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGA
Sbjct: 301 TEKTKEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGA 360
Query: 361 SAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGP 420
SAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGP
Sbjct: 361 SAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGP 420
Query: 421 GGFSFEASGPGNFFFQFG 438
GGFSFEASGPGNFFFQFG
Sbjct: 421 GGFSFEASGPGNFFFQFG 438
>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
[Homo sapiens]
Length = 494
Score = 890 bits (2300), Expect = 0.0
Identities = 437/438 (99%), Positives = 438/438 (100%)
Query: 1 MCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAAC 60
MCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAAC
Sbjct: 57 MCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAAC 116
Query: 61 RSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACH 120
RSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACH
Sbjct: 117 RSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACH 176
Query: 121 RFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQA 180
RFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQA
Sbjct: 177 RFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQA 236
Query: 181 LRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKL 240
LRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKL
Sbjct: 237 LRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKL 296
Query: 241 YCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ 300
YCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ
Sbjct: 297 YCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ 356
Query: 301 TEKTKEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGA 360
TEKTKEHKQLLKNAQLEL+KSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGA
Sbjct: 357 TEKTKEHKQLLKNAQLELRKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGA 416
Query: 361 SAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGP 420
SAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGP
Sbjct: 417 SAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGP 476
Query: 421 GGFSFEASGPGNFFFQFG 438
GGFSFEASGPGNFFFQFG
Sbjct: 477 GGFSFEASGPGNFFFQFG 494
Score = 40.4 bits (93), Expect = 0.003
Identities = 58/299 (19%), Positives = 114/299 (38%), Gaps = 32/299 (10%)
Query: 56 AMAACRSFQRALE---LDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRA 112
A A C A E LD + A+ + E +++ + K+D+ + +A
Sbjct: 3 AAAECDVVMAATEPELLDDQEAKREAE--------TFKEQGNAYYAKKDYNEAYNYYTKA 54
Query: 113 LEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEK 172
++ P + +A L MLGR+ EA A +R+D + G C
Sbjct: 55 IDMCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMA 114
Query: 173 AVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPN 232
A + F +AL + + +A +NA A+ ++ F++ +++ AL P
Sbjct: 115 ACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAP- 173
Query: 233 NIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAV 292
+ + + L + +A ++ +++D T A R C + E+AV
Sbjct: 174 ---ACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAV 230
Query: 293 RDYEKVYQTEKTKEHKQLLKNAQLELKKSKRKD----------------YYKILGVDKN 335
+ + + + E K + + K+K++D Y + LG+D N
Sbjct: 231 QFFVQALRMAPDHE-KACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPN 288
>gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo
sapiens]
Length = 504
Score = 174 bits (441), Expect = 1e-43
Identities = 123/441 (27%), Positives = 208/441 (47%), Gaps = 11/441 (2%)
Query: 3 PKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRS 62
P N Y RA + +G+ + AL D + ++L F L+ G L G A
Sbjct: 68 PDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDD 127
Query: 63 FQRALEL---DHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPAC 119
F++ L+ +++ +AQ + ++ + A F D+ + +D+ LE
Sbjct: 128 FKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGSGDYTAAIAFLDKILEVCVWD 187
Query: 120 HRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQ 179
+ L+AEC G +A S ++ + N +A Y Y E ++ +
Sbjct: 188 AELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRE 247
Query: 180 ALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAK 239
L++ DH++ + K L E + ++G Y A Y + +P+ + +
Sbjct: 248 CLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAEYTVR 307
Query: 240 LYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVY 299
SK K +AI C+ ++++ + A RA+ Y+ E Y+EA++DYE
Sbjct: 308 SKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQ 367
Query: 300 Q-TEKTKEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHS 358
+ E ++ ++ L+ AQ LK+S+++DYYKILGV +NA + EI KAYRK AL HPD
Sbjct: 368 EHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQ 427
Query: 359 GASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQD-LDEEGMNMGDFDPNNIFKAFF 417
+ E +K+ EKKF ++ A +LSDP+ + ++D G+D LD E G +P F +
Sbjct: 428 --NEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQGGGGNP---FHRSW 482
Query: 418 GGPGGFS-FEASGPGNFFFQF 437
GF+ F + GP F F F
Sbjct: 483 NSWQGFNPFSSGGPFRFKFHF 503
Score = 40.8 bits (94), Expect = 0.002
Identities = 43/236 (18%), Positives = 92/236 (38%), Gaps = 18/236 (7%)
Query: 1 MCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAAC 60
+C +A RA + G R+A+ D + + +L + + + LG+ +
Sbjct: 183 VCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSL 242
Query: 61 RSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACH 120
+ L+LD + + +K + + + AE + + ++ P+
Sbjct: 243 SEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIA 302
Query: 121 RFKILKAE----CLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQF 176
+ + E C + + EA V S++L+M+ N +AL R E+ ++A+Q
Sbjct: 303 EYTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQ- 361
Query: 177 FVQALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPN 232
D+E A N + ++ E + K+ + Y++ LG+ N
Sbjct: 362 ---------DYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKI----LGVKRN 404
Score = 31.6 bits (70), Expect = 1.5
Identities = 34/97 (35%), Positives = 47/97 (48%), Gaps = 9/97 (9%)
Query: 253 KLDDAIEDCTNAVKLD-DTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLL 311
+L DA+ AV D D YI AY RRA ++ + + A+ D KV Q K L
Sbjct: 52 QLADALSQFHAAVDGDPDNYI-AYYRRATVFLAMGKSKAALPDLTKVIQL-KMDFTAARL 109
Query: 312 KNAQLELKKSK----RKDYYKILGVDKNASEDEIKKA 344
+ L LK+ K D+ K+L N SE+E K+A
Sbjct: 110 QRGHLLLKQGKLDEAEDDFKKVL--KSNPSENEEKEA 144
>gi|201862587 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform 1
[Homo sapiens]
Length = 420
Score = 91.7 bits (226), Expect = 1e-18
Identities = 52/115 (45%), Positives = 66/115 (57%), Gaps = 24/115 (20%)
Query: 324 KDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILS 383
KDYYKILG+ A+EDEIKKAYRK AL +HPD++ +A E+KFKE+ EA+ +LS
Sbjct: 75 KDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNA------EEKFKEIAEAYDVLS 128
Query: 384 DPKKKTRYDSGQDLDEEGMNMG---------------DFDPNNIFKAFFGGPGGF 423
DPKK+ YD EEG+ G DP+ F +FFGG F
Sbjct: 129 DPKKRGLYD---QYGEEGLKTGGGTSGGSSGSFHYTFHGDPHATFASFFGGSNPF 180
>gi|201862518 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform 2
[Homo sapiens]
Length = 382
Score = 91.7 bits (226), Expect = 1e-18
Identities = 52/115 (45%), Positives = 66/115 (57%), Gaps = 24/115 (20%)
Query: 324 KDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILS 383
KDYYKILG+ A+EDEIKKAYRK AL +HPD++ +A E+KFKE+ EA+ +LS
Sbjct: 37 KDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNA------EEKFKEIAEAYDVLS 90
Query: 384 DPKKKTRYDSGQDLDEEGMNMG---------------DFDPNNIFKAFFGGPGGF 423
DPKK+ YD EEG+ G DP+ F +FFGG F
Sbjct: 91 DPKKRGLYD---QYGEEGLKTGGGTSGGSSGSFHYTFHGDPHATFASFFGGSNPF 142
>gi|56549115 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform 3
[Homo sapiens]
Length = 348
Score = 91.7 bits (226), Expect = 1e-18
Identities = 52/115 (45%), Positives = 66/115 (57%), Gaps = 24/115 (20%)
Query: 324 KDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILS 383
KDYYKILG+ A+EDEIKKAYRK AL +HPD++ +A E+KFKE+ EA+ +LS
Sbjct: 3 KDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNA------EEKFKEIAEAYDVLS 56
Query: 384 DPKKKTRYDSGQDLDEEGMNMG---------------DFDPNNIFKAFFGGPGGF 423
DPKK+ YD EEG+ G DP+ F +FFGG F
Sbjct: 57 DPKKRGLYD---QYGEEGLKTGGGTSGGSSGSFHYTFHGDPHATFASFFGGSNPF 108
>gi|6631085 DnaJ (Hsp40) homolog, subfamily B, member 4 [Homo
sapiens]
Length = 337
Score = 90.1 bits (222), Expect = 4e-18
Identities = 52/115 (45%), Positives = 66/115 (57%), Gaps = 24/115 (20%)
Query: 324 KDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILS 383
KDYY ILG++K AS+++IKKAYRK+AL HPD++ AE +KFKEV EA+ +LS
Sbjct: 3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAE------EKFKEVAEAYEVLS 56
Query: 384 DPKKKTRYDSGQDLDEEGMNMG---------------DFDPNNIFKAFFGGPGGF 423
DPKK+ YD EEG+ G DP+ F AFFGG F
Sbjct: 57 DPKKREIYD---QFGEEGLKGGAGGTDGQGGTFRYTFHGDPHATFAAFFGGSNPF 108
>gi|17388799 DnaJ (Hsp40) homolog, subfamily B, member 6 isoform a
[Homo sapiens]
Length = 326
Score = 89.0 bits (219), Expect = 8e-18
Identities = 51/118 (43%), Positives = 73/118 (61%), Gaps = 23/118 (19%)
Query: 325 DYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSD 384
DYY++LGV ++AS ++IKKAYRK AL HPD+ + E ++E E+KFK+V EA+ +LSD
Sbjct: 3 DYYEVLGVQRHASPEDIKKAYRKLALKWHPDK----NPENKEEAERKFKQVAEAYEVLSD 58
Query: 385 PKKKTRYDSGQDLDEEGMNMG-----DFD-----------PNNIFKAFFGGPGGFSFE 426
KK+ YD +EG+N G FD P+++F+ FFGG FSF+
Sbjct: 59 AKKRDIYDK---YGKEGLNGGGGGGSHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFD 113
>gi|4885495 DnaJ (Hsp40) homolog, subfamily B, member 6 isoform b
[Homo sapiens]
Length = 241
Score = 89.0 bits (219), Expect = 8e-18
Identities = 51/118 (43%), Positives = 73/118 (61%), Gaps = 23/118 (19%)
Query: 325 DYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSD 384
DYY++LGV ++AS ++IKKAYRK AL HPD+ + E ++E E+KFK+V EA+ +LSD
Sbjct: 3 DYYEVLGVQRHASPEDIKKAYRKLALKWHPDK----NPENKEEAERKFKQVAEAYEVLSD 58
Query: 385 PKKKTRYDSGQDLDEEGMNMG-----DFD-----------PNNIFKAFFGGPGGFSFE 426
KK+ YD +EG+N G FD P+++F+ FFGG FSF+
Sbjct: 59 AKKRDIYDK---YGKEGLNGGGGGGSHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFD 113
>gi|4504511 DnaJ (Hsp40) homolog, subfamily A, member 1 [Homo
sapiens]
Length = 397
Score = 87.0 bits (214), Expect = 3e-17
Identities = 47/110 (42%), Positives = 64/110 (58%), Gaps = 10/110 (9%)
Query: 322 KRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTI 381
K YY +LGV NA+++E+KKAYRK AL +HPD++ E +KFK++ +A+ +
Sbjct: 3 KETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKN--------PNEGEKFKQISQAYEV 54
Query: 382 LSDPKKKTRYDSG--QDLDEEGMNMGDFDPNNIFKAFFGGPGGFSFEASG 429
LSD KK+ YD G Q + E G G P +IF FFGG G E G
Sbjct: 55 LSDAKKRELYDKGGEQAIKEGGAGGGFGSPMDIFDMFFGGGGRMQRERRG 104
>gi|194328758 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform 1
[Homo sapiens]
Length = 426
Score = 87.0 bits (214), Expect = 3e-17
Identities = 51/114 (44%), Positives = 66/114 (57%), Gaps = 11/114 (9%)
Query: 319 KKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEA 378
K K YY ILGV +AS +EIKKAYRK AL +HPD++ +E +KFK + +A
Sbjct: 29 KMVKETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKN--------PDEGEKFKLISQA 80
Query: 379 FTILSDPKKKTRYDSG--QDLDEEGMNMGDF-DPNNIFKAFFGGPGGFSFEASG 429
+ +LSDPKK+ YD G Q + E G F P +IF FFGG G + E G
Sbjct: 81 YEVLSDPKKRDVYDQGGEQAIKEGGSGSPSFSSPMDIFDMFFGGGGRMARERRG 134
>gi|194328760 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform 2
[Homo sapiens]
Length = 397
Score = 86.3 bits (212), Expect = 5e-17
Identities = 50/111 (45%), Positives = 65/111 (58%), Gaps = 11/111 (9%)
Query: 322 KRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTI 381
K YY ILGV +AS +EIKKAYRK AL +HPD++ +E +KFK + +A+ +
Sbjct: 3 KETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKN--------PDEGEKFKLISQAYEV 54
Query: 382 LSDPKKKTRYDSG--QDLDEEGMNMGDF-DPNNIFKAFFGGPGGFSFEASG 429
LSDPKK+ YD G Q + E G F P +IF FFGG G + E G
Sbjct: 55 LSDPKKRDVYDQGGEQAIKEGGSGSPSFSSPMDIFDMFFGGGGRMARERRG 105
>gi|24308141 small glutamine-rich tetratricopeptide repeat
(TPR)-containing, beta [Homo sapiens]
Length = 304
Score = 85.1 bits (209), Expect = 1e-16
Identities = 46/118 (38%), Positives = 65/118 (55%), Gaps = 5/118 (4%)
Query: 204 KEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTN 263
K++GN KE NY A + YT+A+ +DPNN A YCNR SKL DAI+DC
Sbjct: 89 KDEGNNHMKEENYAAAVDCYTQAIELDPNN----AVYYCNRAAAQSKLGHYTDAIKDCEK 144
Query: 264 AVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTE-KTKEHKQLLKNAQLELKK 320
A+ +D Y KAY R ++EEAV Y+K + + +K LK A+ +L++
Sbjct: 145 AIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLRE 202
Score = 53.5 bits (127), Expect = 4e-07
Identities = 27/81 (33%), Positives = 44/81 (54%)
Query: 3 PKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRS 62
P NA YY NRAA LG + +A+ D ++++ +D + + + R G +L A S
Sbjct: 116 PNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTS 175
Query: 63 FQRALELDHKNAQAQQEFKNA 83
+Q+AL+LD +N + K A
Sbjct: 176 YQKALDLDPENDSYKSNLKIA 196
Score = 33.1 bits (74), Expect = 0.51
Identities = 22/91 (24%), Positives = 43/91 (47%)
Query: 98 EKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADAL 157
++ ++ V C +A+E P + +A + LG Y +A + +DS + A
Sbjct: 97 KEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAY 156
Query: 158 YVRGLCLYYEDCIEKAVQFFVQALRMAPDHE 188
GL L + E+AV + +AL + P+++
Sbjct: 157 GRMGLALTALNKFEEAVTSYQKALDLDPEND 187
>gi|47777312 DnaJ (Hsp40) homolog, subfamily B, member 3 [Homo
sapiens]
Length = 145
Score = 84.3 bits (207), Expect = 2e-16
Identities = 48/118 (40%), Positives = 67/118 (56%), Gaps = 17/118 (14%)
Query: 325 DYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSD 384
DYY++L V + AS + IKKAYRK AL HPD+ + E ++E E++FK+V EA+ +LSD
Sbjct: 3 DYYEVLDVPRQASSEAIKKAYRKLALKWHPDK----NPENKEEAERRFKQVAEAYEVLSD 58
Query: 385 PKKKTRYDSGQDLDEEGMNMGD-------------FDPNNIFKAFFGGPGGFSFEASG 429
KK+ YD + EG G DP ++F+ FFGG FSF+ G
Sbjct: 59 AKKRDIYDRYGEAGAEGGCTGGRPFEDPFEYVFSFRDPADVFREFFGGQDPFSFDLLG 116
>gi|23503241 DnaJ homolog, subfamily B, member 8 [Homo sapiens]
Length = 232
Score = 82.0 bits (201), Expect = 1e-15
Identities = 51/115 (44%), Positives = 69/115 (60%), Gaps = 17/115 (14%)
Query: 325 DYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSD 384
+YY++LGV +AS ++IKKAYRK AL HPD+ + + ++E EKKFK V EA+ +LSD
Sbjct: 3 NYYEVLGVQASASPEDIKKAYRKLALRWHPDK----NPDNKEEAEKKFKLVSEAYEVLSD 58
Query: 385 PKKKTRYD-SGQDLDEEGMNM-----GDFD-------PNNIFKAFFGGPGGFSFE 426
KK++ YD +G D G FD P +IF+ FFGG FSFE
Sbjct: 59 SKKRSLYDRAGCDSWRAGGGASTPYHSPFDTGYTFRNPEDIFREFFGGLDPFSFE 113
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 79.3 bits (194), Expect = 6e-15
Identities = 59/245 (24%), Positives = 110/245 (44%), Gaps = 25/245 (10%)
Query: 81 KNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQ 140
+N ++ +++ ++K+DF + D+A E P + +A G Y + +
Sbjct: 220 ENKKQALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCR 279
Query: 141 SVASDILRMDSTNAD------ALYVR-GLCLYYEDCIEKAVQFFVQAL--RMAPDHEKAC 191
+ + + N + Y R G + E+ + A+ F+ ++L PD K C
Sbjct: 280 ELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKC 339
Query: 192 ------------IACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAK 239
+A N +K GN+ F++G+Y A + YTEA+ +P + AK
Sbjct: 340 QQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKD----AK 395
Query: 240 LYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVY 299
LY NR +KL + A++DC ++L+ T+IK Y R+A + Y +A+ Y+K
Sbjct: 396 LYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKAL 455
Query: 300 QTEKT 304
+ +
Sbjct: 456 DLDSS 460
Score = 65.5 bits (158), Expect = 9e-11
Identities = 82/363 (22%), Positives = 147/363 (40%), Gaps = 22/363 (6%)
Query: 3 PKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRS 62
P N Y NR+A G +++A D ++V L + +G+ R+ L A R+
Sbjct: 35 PHNHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRT 94
Query: 63 FQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRF 122
++ L+ + N Q ++ +N A ++AE F F M + + R
Sbjct: 95 YEEGLKHEANNPQLKEGLQNMEA-----RLAERKFMN------PFNMPNLYQKLESDPRT 143
Query: 123 KILKA-----ECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFF 177
+ L + E + L P R+ +T + L V + E+ I
Sbjct: 144 RTLLSDPTYRELIEQLRNKPSDLGTKLQDPRIMTTLSVLLGVDLGSMDEEEEIATPPPPP 203
Query: 178 VQALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNN---I 234
P+ + + +ALK +KE GN A+K+ ++ A + Y +A +DP N I
Sbjct: 204 PPKKETKPEPMEEDLPENKKQALK-EKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYI 262
Query: 235 KTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRD 294
A +Y +G N + AIE + KAY R Y E+Y++A+
Sbjct: 263 TNQAAVYFEKGDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHF 322
Query: 295 YEKVYQTEKTKEHKQLLKNAQLELKKSKRKDYYK--ILGVDKNASEDEIKKAYRKRALMH 352
Y K +T + + + A+ LK+ +R Y + +KN + +K +A+ H
Sbjct: 323 YNKSLAEHRTPDVLKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKH 382
Query: 353 HPD 355
+ +
Sbjct: 383 YTE 385
Score = 60.8 bits (146), Expect = 2e-09
Identities = 54/187 (28%), Positives = 83/187 (44%), Gaps = 18/187 (9%)
Query: 204 KEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTN 263
KE GNKA GN A + Y+EA+ +DP+N LY NR +K A ED
Sbjct: 8 KEKGNKALSVGNIDDALQCYSEAIKLDPHN----HVLYSNRSAAYAKKGDYQKAYEDGCK 63
Query: 264 AVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTE-KTKEHKQLLKNAQLELKKSK 322
V L + K Y R+A ++EEA R YE+ + E + K+ L+N + L + K
Sbjct: 64 TVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNMEARLAERK 123
Query: 323 RKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTIL 382
+ + + + + D R R L+ P E+ ++ K ++G T L
Sbjct: 124 FMNPFNMPNLYQKLESDP-----RTRTLLSDP-----TYRELIEQLRNKPSDLG---TKL 170
Query: 383 SDPKKKT 389
DP+ T
Sbjct: 171 QDPRIMT 177
Score = 48.5 bits (114), Expect = 1e-05
Identities = 26/98 (26%), Positives = 50/98 (51%)
Query: 3 PKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRS 62
PK+A Y NRAA L F+ AL D ++ ++L+ +F++G+ R+ ++ + A
Sbjct: 391 PKDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDV 450
Query: 63 FQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKR 100
+Q+AL+LD +A ++ + D ++R
Sbjct: 451 YQKALDLDSSCKEAADGYQRCMMAQYNRHDSPEDVKRR 488
Score = 32.0 bits (71), Expect = 1.1
Identities = 46/228 (20%), Positives = 87/228 (38%), Gaps = 25/228 (10%)
Query: 3 PKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRS 62
P N +Y N+AA G + + ++++ + + + K + +GN+
Sbjct: 256 PTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEEK 315
Query: 63 FQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRF 122
++ A+ +K+ + + EKI K R D ALE
Sbjct: 316 YKDAIHFYNKSLAEHRTPDVLKKCQQAEKIL-----KEQERLAYINPDLALE-------E 363
Query: 123 KILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALR 182
K EC G YP+A ++ ++ + +A R C + A++ + ++
Sbjct: 364 KNKGNECF-QKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECIQ 422
Query: 183 MAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGID 230
+ P K R A AL+A K+ Y A ++Y +AL +D
Sbjct: 423 LEPTFIKG--YTRKAAALEAMKD----------YTKAMDVYQKALDLD 458
>gi|194306642 DnaJ (Hsp40) homolog, subfamily B, member 12 [Homo
sapiens]
Length = 409
Score = 79.0 bits (193), Expect = 8e-15
Identities = 43/108 (39%), Positives = 63/108 (58%), Gaps = 18/108 (16%)
Query: 324 KDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILS 383
KDYY+ILGV + AS++++KKAYR+ AL HPD++ A + FK +G A+ +LS
Sbjct: 143 KDYYEILGVSRGASDEDLKKAYRRLALKFHPDKNHAPGA------TEAFKAIGTAYAVLS 196
Query: 384 DPKKKTRYDS-GQDLDE---EGMNMGDF--------DPNNIFKAFFGG 419
+P+K+ +YD G D + G GDF P ++F FFGG
Sbjct: 197 NPEKRKQYDQFGDDKSQAARHGHGHGDFHRGFEADISPEDLFNMFFGG 244
>gi|194306640 DnaJ (Hsp40) homolog, subfamily B, member 12 [Homo
sapiens]
Length = 409
Score = 79.0 bits (193), Expect = 8e-15
Identities = 43/108 (39%), Positives = 63/108 (58%), Gaps = 18/108 (16%)
Query: 324 KDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILS 383
KDYY+ILGV + AS++++KKAYR+ AL HPD++ A + FK +G A+ +LS
Sbjct: 143 KDYYEILGVSRGASDEDLKKAYRRLALKFHPDKNHAPGA------TEAFKAIGTAYAVLS 196
Query: 384 DPKKKTRYDS-GQDLDE---EGMNMGDF--------DPNNIFKAFFGG 419
+P+K+ +YD G D + G GDF P ++F FFGG
Sbjct: 197 NPEKRKQYDQFGDDKSQAARHGHGHGDFHRGFEADISPEDLFNMFFGG 244
>gi|5453690 DnaJ (Hsp40) homolog, subfamily B, member 1 [Homo
sapiens]
Length = 340
Score = 77.4 bits (189), Expect = 2e-14
Identities = 44/116 (37%), Positives = 66/116 (56%), Gaps = 22/116 (18%)
Query: 324 KDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILS 383
KDYY+ LG+ + AS++EIK+AYR++AL +HPD++ A E+KFKE+ EA+ +LS
Sbjct: 3 KDYYQTLGLARGASDEEIKRAYRRQALRYHPDKNKEPGA------EEKFKEIAEAYDVLS 56
Query: 384 DPKKKTRYD--SGQDLDEEGMNMGD--------------FDPNNIFKAFFGGPGGF 423
DP+K+ +D + L G + G DP+ +F FFGG F
Sbjct: 57 DPRKREIFDRYGEEGLKGSGPSGGSGGGANGTSFSYTFHGDPHAMFAEFFGGRNPF 112
>gi|22749377 DnaJ (Hsp40) homolog, subfamily C, member 18 [Homo
sapiens]
Length = 358
Score = 75.9 bits (185), Expect = 7e-14
Identities = 49/154 (31%), Positives = 79/154 (51%), Gaps = 30/154 (19%)
Query: 283 MDTEQYEEAVRDYEKVYQTE--KTKEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDE 340
M ++ +++ ++ + Q E T +QLL +++ K ++YY+ILGV ++AS++E
Sbjct: 42 MKAQKEKKSENEWTQTRQGEGNSTYSEEQLLGVQRIK----KCRNYYEILGVSRDASDEE 97
Query: 341 IKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEE 400
+KKAYRK AL HPD++ A FK +G AF +LS+P K+ RYD + +E
Sbjct: 98 LKKAYRKLALKFHPDKNCAPGA------TDAFKAIGNAFAVLSNPDKRLRYD---EYGDE 148
Query: 401 GMNM---------------GDFDPNNIFKAFFGG 419
+ D P +F FFGG
Sbjct: 149 QVTFTAPRARPYNYYRDFEADITPEELFNVFFGG 182
>gi|88501736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform a
[Homo sapiens]
Length = 277
Score = 75.5 bits (184), Expect = 9e-14
Identities = 47/112 (41%), Positives = 66/112 (58%), Gaps = 9/112 (8%)
Query: 326 YYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDP 385
YY+IL V ++AS D+IKKAYR++AL HPD+ + + ++ EKKFKEV EA+ +LSD
Sbjct: 4 YYEILDVPRSASADDIKKAYRRKALQWHPDK----NPDNKEFAEKKFKEVAEAYEVLSDK 59
Query: 386 KKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFSFEASGPGNFFFQF 437
K+ YD EG+ P+ +A GGP GF+F P F +F
Sbjct: 60 HKREIYDR---YGREGLTGTGTGPSRA-EAGSGGP-GFTFTFRSPEEVFREF 106
>gi|27151736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform b
[Homo sapiens]
Length = 324
Score = 75.5 bits (184), Expect = 9e-14
Identities = 47/112 (41%), Positives = 66/112 (58%), Gaps = 9/112 (8%)
Query: 326 YYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDP 385
YY+IL V ++AS D+IKKAYR++AL HPD+ + + ++ EKKFKEV EA+ +LSD
Sbjct: 4 YYEILDVPRSASADDIKKAYRRKALQWHPDK----NPDNKEFAEKKFKEVAEAYEVLSDK 59
Query: 386 KKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFSFEASGPGNFFFQF 437
K+ YD EG+ P+ +A GGP GF+F P F +F
Sbjct: 60 HKREIYDR---YGREGLTGTGTGPSRA-EAGSGGP-GFTFTFRSPEEVFREF 106
>gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens]
Length = 292
Score = 75.5 bits (184), Expect = 9e-14
Identities = 38/100 (38%), Positives = 63/100 (63%), Gaps = 1/100 (1%)
Query: 204 KEDGNKAFKEGNYKLAYELYTEALGIDPNNI-KTNAKLYCNRGTVNSKLRKLDDAIEDCT 262
KE+GN+ FK+G+Y A Y+ AL + P+ K + L+ NR K K + AI DC+
Sbjct: 120 KEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCS 179
Query: 263 NAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTE 302
A++L+ +YI+A LRRA+ Y T++ +EA+ DY+ + + +
Sbjct: 180 KAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKD 219
Score = 35.4 bits (80), Expect = 0.10
Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 5/83 (6%)
Query: 1 MCP-----KNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGN 55
MCP + + + NRAA M + A+ D ++++L+ S++R LR + +
Sbjct: 145 MCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDK 204
Query: 56 AMAACRSFQRALELDHKNAQAQQ 78
A ++ LE D QA++
Sbjct: 205 LDEALEDYKSILEKDPSIHQARE 227
Score = 31.2 bits (69), Expect = 1.9
Identities = 39/179 (21%), Positives = 72/179 (40%), Gaps = 16/179 (8%)
Query: 67 LELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFK--I 124
+EL+ KN +++ K ++ F+K D+ + RALE P+C + + I
Sbjct: 98 IELE-KNMSDEEKQKRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSI 156
Query: 125 LKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYE-----DCIEKAVQFFVQ 179
L + A + + + +D + N Y+R + E D +++A++ +
Sbjct: 157 LFSNRAAARMKQDKKEMAINDCSKAIQLNPS--YIRAILRRAELYEKTDKLDEALEDYKS 214
Query: 180 ALRMAPDHEKACIACRNAKALKAKKEDGNKAFKE---GNYKLAYELYTEALGIDPNNIK 235
L P +A AC L + E+ N+ KE G K L G+ N +
Sbjct: 215 ILEKDPSIHQAREACMR---LPKQIEERNERLKEEMLGKLKDLGNLVLRPFGLSTENFQ 270
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 75.1 bits (183), Expect = 1e-13
Identities = 62/194 (31%), Positives = 92/194 (47%), Gaps = 12/194 (6%)
Query: 179 QALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNA 238
++L + E+ I + KAL KE GNK FK+G Y A + YT+ + DP N
Sbjct: 113 ESLSQESESEEDGIHVDSQKAL-VLKEKGNKYFKQGKYDEAIDCYTKGMDADPYN----P 167
Query: 239 KLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKV 298
L NR + +L+K A DC AV L+ +Y KAY RR ++ EEA +DYE+V
Sbjct: 168 VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERV 227
Query: 299 YQTEKT--KEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDE---IKKAYRKRALMHH 353
+ E + +L K +Q SK Y K + ++E E I+ K+ +
Sbjct: 228 LELEPNNFEATNELRKISQ--ALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISE 285
Query: 354 PDRHSGASAEVQKE 367
DR +G E + E
Sbjct: 286 KDRGNGFFKEGKYE 299
Score = 74.7 bits (182), Expect = 2e-13
Identities = 49/150 (32%), Positives = 72/150 (48%), Gaps = 10/150 (6%)
Query: 181 LRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKL 240
++ K A +N + ++K+ GN FKEG Y+ A E YT + D NA L
Sbjct: 263 IKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADG----ANALL 318
Query: 241 YCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ 300
NR K++K ++A +DCT A+ LD +Y KA+ RR + EA +D+E V
Sbjct: 319 PANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLL 378
Query: 301 TEKTKEHKQLLKNAQLELKKSKRKDYYKIL 330
E K A EL K K+K K++
Sbjct: 379 LEPGN------KQAVTELSKIKKKPLKKVI 402
Score = 53.1 bits (126), Expect = 5e-07
Identities = 60/292 (20%), Positives = 107/292 (36%), Gaps = 43/292 (14%)
Query: 3 PKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRS 62
P N NRA+ L +F A D +V L+ S+ + + R G +L A +
Sbjct: 164 PYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKD 223
Query: 63 FQRALELDHKNAQAQQEFKNANAVM------------------------------EYEKI 92
++R LEL+ N +A E + + + + + I
Sbjct: 224 YERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAI 283
Query: 93 AETD-----FEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDIL 147
+E D F++ + + + C R + A +A + +Y EA+ + +
Sbjct: 284 SEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAI 343
Query: 148 RMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDG 207
+D + + A RG + + +A Q F L + P +++A + K KK+
Sbjct: 344 LLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAV-----TELSKIKKKPL 398
Query: 208 NKAFKE--GNYKLAYELYTEALGIDPNNIKTN-AKLYCNRGTVNSKLRKLDD 256
K E GN ++ P N N A + GT + K DD
Sbjct: 399 KKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNSSQDD 450
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 75.1 bits (183), Expect = 1e-13
Identities = 62/194 (31%), Positives = 92/194 (47%), Gaps = 12/194 (6%)
Query: 179 QALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNA 238
++L + E+ I + KAL KE GNK FK+G Y A + YT+ + DP N
Sbjct: 113 ESLSQESESEEDGIHVDSQKAL-VLKEKGNKYFKQGKYDEAIDCYTKGMDADPYN----P 167
Query: 239 KLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKV 298
L NR + +L+K A DC AV L+ +Y KAY RR ++ EEA +DYE+V
Sbjct: 168 VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERV 227
Query: 299 YQTEKT--KEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDE---IKKAYRKRALMHH 353
+ E + +L K +Q SK Y K + ++E E I+ K+ +
Sbjct: 228 LELEPNNFEATNELRKISQ--ALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISE 285
Query: 354 PDRHSGASAEVQKE 367
DR +G E + E
Sbjct: 286 KDRGNGFFKEGKYE 299
Score = 70.9 bits (172), Expect = 2e-12
Identities = 47/144 (32%), Positives = 69/144 (47%), Gaps = 10/144 (6%)
Query: 181 LRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKL 240
++ K A +N + ++K+ GN FKEG Y+ A E YT + D NA L
Sbjct: 263 IKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADG----ANALL 318
Query: 241 YCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ 300
NR K++K ++A +DCT A+ LD +Y KA+ RR + EA +D+E V
Sbjct: 319 PANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLL 378
Query: 301 TEKTKEHKQLLKNAQLELKKSKRK 324
E K A EL K K++
Sbjct: 379 LEPGN------KQAVTELSKIKKE 396
Score = 48.9 bits (115), Expect = 9e-06
Identities = 44/223 (19%), Positives = 85/223 (38%), Gaps = 35/223 (15%)
Query: 3 PKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRS 62
P N NRA+ L +F A D +V L+ S+ + + R G +L A +
Sbjct: 164 PYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKD 223
Query: 63 FQRALELDHKNAQAQQEFKNANAVM------------------------------EYEKI 92
++R LEL+ N +A E + + + + + I
Sbjct: 224 YERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAI 283
Query: 93 AETD-----FEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDIL 147
+E D F++ + + + C R + A +A + +Y EA+ + +
Sbjct: 284 SEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAI 343
Query: 148 RMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKA 190
+D + + A RG + + +A Q F L + P +++A
Sbjct: 344 LLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQA 386
Score = 40.8 bits (94), Expect = 0.002
Identities = 24/75 (32%), Positives = 35/75 (46%)
Query: 5 NASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQ 64
NA NRA + + ++ EA D Q++ LD S+ + R G LG A + F+
Sbjct: 315 NALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFE 374
Query: 65 RALELDHKNAQAQQE 79
L L+ N QA E
Sbjct: 375 TVLLLEPGNKQAVTE 389
>gi|72534740 DnaJ (Hsp40) homolog, subfamily B, member 14 isoform 1
[Homo sapiens]
Length = 379
Score = 75.1 bits (183), Expect = 1e-13
Identities = 41/115 (35%), Positives = 65/115 (56%), Gaps = 20/115 (17%)
Query: 318 LKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGE 377
L +K K+YY++LGV K+A ++++KKAYRK AL HPD++ A FK++G
Sbjct: 101 LSINKCKNYYEVLGVTKDAGDEDLKKAYRKLALKFHPDKNHAPGA------TDAFKKIGN 154
Query: 378 AFTILSDPKKKTRYDSGQDLDEEGMN-------------MGDFDPNNIFKAFFGG 419
A+ +LS+P+K+ +YD + +E+ N D P ++F FFGG
Sbjct: 155 AYAVLSNPEKRKQYDLTGN-EEQACNHQNNGRFNFHRGCEADITPEDLFNIFFGG 208
>gi|21553335 DnaJ (Hsp40) homolog, subfamily B, member 7 [Homo
sapiens]
Length = 309
Score = 74.3 bits (181), Expect = 2e-13
Identities = 46/114 (40%), Positives = 66/114 (57%), Gaps = 20/114 (17%)
Query: 325 DYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSD 384
DYY++LG+ + AS ++IKKAY K AL HPD+ + E ++E E+KFKEV EA+ +LS+
Sbjct: 3 DYYEVLGLQRYASPEDIKKAYHKVALKWHPDK----NPENKEEAERKFKEVAEAYEVLSN 58
Query: 385 PKKKTRYDSGQDLDEEGMNMG--DFD-----------PNNIFKAFFGGPGGFSF 425
+K+ YD EG+N G FD P+++FK F FSF
Sbjct: 59 DEKRDIYDK---YGTEGLNGGGSHFDDECEYGFTFHKPDDVFKEIFHERDPFSF 109
>gi|7706495 DnaJ (Hsp40) homolog, subfamily B, member 11 precursor
[Homo sapiens]
Length = 358
Score = 73.9 bits (180), Expect = 3e-13
Identities = 42/99 (42%), Positives = 62/99 (62%), Gaps = 9/99 (9%)
Query: 324 KDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILS 383
+D+YKILGV ++AS +IKKAYRK AL HPDR+ + ++KF+++G A+ +LS
Sbjct: 24 RDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPD-----DPQAQEKFQDLGAAYEVLS 78
Query: 384 DPKKKTRYDSGQDLDEEGMNMG-DFDPNNIFKAFFGGPG 421
D +K+ +YD+ EEG+ G +IF FFG G
Sbjct: 79 DSEKRKQYDT---YGEEGLKDGHQSSHGDIFSHFFGDFG 114
>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
A [Homo sapiens]
Length = 608
Score = 72.8 bits (177), Expect = 6e-13
Identities = 47/147 (31%), Positives = 73/147 (49%), Gaps = 3/147 (2%)
Query: 185 PDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTN-AKLYCN 243
P+ A + + +A K GNK FK G Y+ A + YTEA+ + P + + Y N
Sbjct: 99 PEGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQN 158
Query: 244 RGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEK 303
R +L+K + +DCT AV+L+ Y+KA RRA+ + + +E + D V E
Sbjct: 159 RAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEG 218
Query: 304 -TKEHKQLLKNAQLE-LKKSKRKDYYK 328
+ LL + L+ L K K K+ YK
Sbjct: 219 FQNQQSMLLADKVLKLLGKEKAKEKYK 245
Score = 39.3 bits (90), Expect = 0.007
Identities = 60/306 (19%), Positives = 114/306 (37%), Gaps = 31/306 (10%)
Query: 1 MCP--KN---ASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGN 55
+CP KN +++Y NRAA L +++E D ++V L+ +V+ R K H L N
Sbjct: 143 LCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDN 202
Query: 56 AMAACRSFQRALELDHKNAQAQQEFKNANAVMEY--EKIAETDFEKRD--FRKVVFCMDR 111
L+ Q QQ A+ V++ ++ A+ ++ R+ F
Sbjct: 203 KKECLEDVTAVCILE--GFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSY 260
Query: 112 ALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIE 171
F +LK E + E + + L + + Y++ E+ +
Sbjct: 261 FSSFTDDIISQPMLKGE------KSDEDKDKEGEALEVKENSG---YLKAKQYMEEENYD 311
Query: 172 KAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDP 231
K + + + + + R L GN A + + +
Sbjct: 312 KIISECSKEIDAEGKYMAEALLLRATFYLLI-----------GNANAAKPDLDKVISLKE 360
Query: 232 NNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEA 291
N+K A RG++ + ++ + +D A +D Y R Q + +Q EEA
Sbjct: 361 ANVKLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEA 420
Query: 292 VRDYEK 297
V D+++
Sbjct: 421 VADFDE 426
>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 70.9 bits (172), Expect = 2e-12
Identities = 47/144 (32%), Positives = 69/144 (47%), Gaps = 10/144 (6%)
Query: 181 LRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKL 240
++ K A +N + ++K+ GN FKEG Y+ A E YT + D NA L
Sbjct: 104 IKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADG----ANALL 159
Query: 241 YCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ 300
NR K++K ++A +DCT A+ LD +Y KA+ RR + EA +D+E V
Sbjct: 160 PANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLL 219
Query: 301 TEKTKEHKQLLKNAQLELKKSKRK 324
E K A EL K K++
Sbjct: 220 LEPGN------KQAVTELSKIKKE 237
Score = 50.8 bits (120), Expect = 2e-06
Identities = 42/136 (30%), Positives = 63/136 (46%), Gaps = 7/136 (5%)
Query: 237 NAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYE 296
N L NR + +L+K A DC AV L+ +Y KAY RR ++ EEA +DYE
Sbjct: 7 NPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYE 66
Query: 297 KVYQTEKT--KEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDE---IKKAYRKRALM 351
+V + E + +L K +Q SK Y K + ++E E I+ K+ +
Sbjct: 67 RVLELEPNNFEATNELRKISQ--ALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAI 124
Query: 352 HHPDRHSGASAEVQKE 367
DR +G E + E
Sbjct: 125 SEKDRGNGFFKEGKYE 140
Score = 48.9 bits (115), Expect = 9e-06
Identities = 44/223 (19%), Positives = 85/223 (38%), Gaps = 35/223 (15%)
Query: 3 PKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRS 62
P N NRA+ L +F A D +V L+ S+ + + R G +L A +
Sbjct: 5 PYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKD 64
Query: 63 FQRALELDHKNAQAQQEFKNANAVM------------------------------EYEKI 92
++R LEL+ N +A E + + + + + I
Sbjct: 65 YERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAI 124
Query: 93 AETD-----FEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDIL 147
+E D F++ + + + C R + A +A + +Y EA+ + +
Sbjct: 125 SEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAI 184
Query: 148 RMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKA 190
+D + + A RG + + +A Q F L + P +++A
Sbjct: 185 LLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQA 227
Score = 40.8 bits (94), Expect = 0.002
Identities = 24/75 (32%), Positives = 35/75 (46%)
Query: 5 NASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQ 64
NA NRA + + ++ EA D Q++ LD S+ + R G LG A + F+
Sbjct: 156 NALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFE 215
Query: 65 RALELDHKNAQAQQE 79
L L+ N QA E
Sbjct: 216 TVLLLEPGNKQAVTE 230
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,595,574
Number of Sequences: 37866
Number of extensions: 674656
Number of successful extensions: 3456
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 138
Number of HSP's successfully gapped in prelim test: 135
Number of HSP's that attempted gapping in prelim test: 2805
Number of HSP's gapped (non-prelim): 603
length of query: 438
length of database: 18,247,518
effective HSP length: 105
effective length of query: 333
effective length of database: 14,271,588
effective search space: 4752438804
effective search space used: 4752438804
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.