Search of human proteins with 115387099

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo
sapiens]
         (1585 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens]  3278   0.0  
gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens]    1461   0.0  
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [...  1158   0.0  
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s...   212   3e-54
gi|118572606 hemicentin 1 [Homo sapiens]                              198   3e-50
gi|163792198 latrophilin 3 precursor [Homo sapiens]                   186   2e-46
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ...   172   2e-42
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]          159   2e-38
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]          159   2e-38
gi|148806925 EGF, latrophilin and seven transmembrane domain con...   158   3e-38
gi|6912464 latrophilin 2 precursor [Homo sapiens]                     158   3e-38
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo...   156   1e-37
gi|45433552 G protein-coupled receptor 133 [Homo sapiens]             155   4e-37
gi|4505737 complement factor properdin precursor [Homo sapiens]       152   2e-36
gi|223671861 complement factor properdin precursor [Homo sapiens]     152   2e-36
gi|40317628 thrombospondin 2 precursor [Homo sapiens]                 145   4e-34
gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]           145   4e-34
gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]           145   4e-34
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]           145   4e-34
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]                    143   2e-33
gi|40317626 thrombospondin 1 precursor [Homo sapiens]                 142   2e-33
gi|59710093 G-protein coupled receptor 112 [Homo sapiens]             141   6e-33
gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo sapi...   138   4e-32
gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]   136   1e-31
gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]   136   1e-31
gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]   136   1e-31
gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]   136   1e-31
gi|148719671 G-protein coupled receptor 116 [Homo sapiens]            136   2e-31
gi|148719673 G-protein coupled receptor 116 [Homo sapiens]            136   2e-31
gi|147904700 semaphorin 5A [Homo sapiens]                             135   3e-31

>gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens]
          Length = 1585

 Score = 3278 bits (8500), Expect = 0.0
 Identities = 1585/1585 (100%), Positives = 1585/1585 (100%)

Query: 1    MENTGWMGKGHRMTPACPLLLSVILSLRLATAFDPAPSACSALASGVLYGAFSLQDLFPT 60
            MENTGWMGKGHRMTPACPLLLSVILSLRLATAFDPAPSACSALASGVLYGAFSLQDLFPT
Sbjct: 1    MENTGWMGKGHRMTPACPLLLSVILSLRLATAFDPAPSACSALASGVLYGAFSLQDLFPT 60

Query: 61   IASGCSWTLENPDPTKYSLYLRFNRQEQVCAHFAPRLLPLDHYLVNFTCLRPSPEEAVAQ 120
            IASGCSWTLENPDPTKYSLYLRFNRQEQVCAHFAPRLLPLDHYLVNFTCLRPSPEEAVAQ
Sbjct: 61   IASGCSWTLENPDPTKYSLYLRFNRQEQVCAHFAPRLLPLDHYLVNFTCLRPSPEEAVAQ 120

Query: 121  AESEVGRPEEEEAEAAAGLELCSGSGPFTFLHFDKNFVQLCLSAEPSEAPRLLAPAALAF 180
            AESEVGRPEEEEAEAAAGLELCSGSGPFTFLHFDKNFVQLCLSAEPSEAPRLLAPAALAF
Sbjct: 121  AESEVGRPEEEEAEAAAGLELCSGSGPFTFLHFDKNFVQLCLSAEPSEAPRLLAPAALAF 180

Query: 181  RFVEVLLINNNNSSQFTCGVLCRWSEECGRAAGRACGFAQPGCSCPGEAGAGSTTTTSPG 240
            RFVEVLLINNNNSSQFTCGVLCRWSEECGRAAGRACGFAQPGCSCPGEAGAGSTTTTSPG
Sbjct: 181  RFVEVLLINNNNSSQFTCGVLCRWSEECGRAAGRACGFAQPGCSCPGEAGAGSTTTTSPG 240

Query: 241  PPAAHTLSNALVPGGPAPPAEADLHSGSSNDLFTTEMRYGEEPEEEPKVKTQWPRSADEP 300
            PPAAHTLSNALVPGGPAPPAEADLHSGSSNDLFTTEMRYGEEPEEEPKVKTQWPRSADEP
Sbjct: 241  PPAAHTLSNALVPGGPAPPAEADLHSGSSNDLFTTEMRYGEEPEEEPKVKTQWPRSADEP 300

Query: 301  GLYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSAT 360
            GLYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSAT
Sbjct: 301  GLYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSAT 360

Query: 361  CPVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMAACPVEG 420
            CPVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMAACPVEG
Sbjct: 361  CPVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMAACPVEG 420

Query: 421  QWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSKWGP 480
            QWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSKWGP
Sbjct: 421  QWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSKWGP 480

Query: 481  WNAWSLCSKTCDTGWQRRFRMCQATGTQGYPCEGTGEEVKPCSEKRCPAFHEMCRDEYVM 540
            WNAWSLCSKTCDTGWQRRFRMCQATGTQGYPCEGTGEEVKPCSEKRCPAFHEMCRDEYVM
Sbjct: 481  WNAWSLCSKTCDTGWQRRFRMCQATGTQGYPCEGTGEEVKPCSEKRCPAFHEMCRDEYVM 540

Query: 541  LMTWKKAAAGEIIYNKCPPNASGSASRRCLLSAQGVAYWGLPSFARCISHEYRYLYLSLR 600
            LMTWKKAAAGEIIYNKCPPNASGSASRRCLLSAQGVAYWGLPSFARCISHEYRYLYLSLR
Sbjct: 541  LMTWKKAAAGEIIYNKCPPNASGSASRRCLLSAQGVAYWGLPSFARCISHEYRYLYLSLR 600

Query: 601  EHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDLLFSVDILRNVTDTFKRATYVPSAD 660
            EHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDLLFSVDILRNVTDTFKRATYVPSAD
Sbjct: 601  EHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDLLFSVDILRNVTDTFKRATYVPSAD 660

Query: 661  DVQRFFQVVSFMVDAENKEKWDDAQQVSPGSVHLLRVVEDFIHLVGDALKAFQSSLIVTD 720
            DVQRFFQVVSFMVDAENKEKWDDAQQVSPGSVHLLRVVEDFIHLVGDALKAFQSSLIVTD
Sbjct: 661  DVQRFFQVVSFMVDAENKEKWDDAQQVSPGSVHLLRVVEDFIHLVGDALKAFQSSLIVTD 720

Query: 721  NLVISIQREPVSAVSSDITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSSPGKPATSGAA 780
            NLVISIQREPVSAVSSDITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSSPGKPATSGAA
Sbjct: 721  NLVISIQREPVSAVSSDITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSSPGKPATSGAA 780

Query: 781  GSPGRGRGPGTVPPGPGHSHQRLLPADPDESSYFVIGAVLYRTLGLILPPPRPPLAVTSR 840
            GSPGRGRGPGTVPPGPGHSHQRLLPADPDESSYFVIGAVLYRTLGLILPPPRPPLAVTSR
Sbjct: 781  GSPGRGRGPGTVPPGPGHSHQRLLPADPDESSYFVIGAVLYRTLGLILPPPRPPLAVTSR 840

Query: 841  VMTVTVRPPTQPPAEPLITVELSYIINGTTDPHCASWDYSRADASSGDWDTENCQTLETQ 900
            VMTVTVRPPTQPPAEPLITVELSYIINGTTDPHCASWDYSRADASSGDWDTENCQTLETQ
Sbjct: 841  VMTVTVRPPTQPPAEPLITVELSYIINGTTDPHCASWDYSRADASSGDWDTENCQTLETQ 900

Query: 901  AAHTRCQCQHLSTFAVLAQPPKDLTLELAGSPSVPLVIGCAVSCMALLTLLAIYAAFWRF 960
            AAHTRCQCQHLSTFAVLAQPPKDLTLELAGSPSVPLVIGCAVSCMALLTLLAIYAAFWRF
Sbjct: 901  AAHTRCQCQHLSTFAVLAQPPKDLTLELAGSPSVPLVIGCAVSCMALLTLLAIYAAFWRF 960

Query: 961  IKSERSIILLNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWVLTEAWQ 1020
            IKSERSIILLNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWVLTEAWQ
Sbjct: 961  IKSERSIILLNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWVLTEAWQ 1020

Query: 1021 SYLAVIGRMRTRLVRKRFLCLGWGLPALVVAVSVGFTRTKGYGTSSYCWLSLEGGLLYAF 1080
            SYLAVIGRMRTRLVRKRFLCLGWGLPALVVAVSVGFTRTKGYGTSSYCWLSLEGGLLYAF
Sbjct: 1021 SYLAVIGRMRTRLVRKRFLCLGWGLPALVVAVSVGFTRTKGYGTSSYCWLSLEGGLLYAF 1080

Query: 1081 VGPAAVIVLVNMLIGIIVFNKLMARDGISDKSKKQRAGSERCPWASLLLPCSACGAVPSP 1140
            VGPAAVIVLVNMLIGIIVFNKLMARDGISDKSKKQRAGSERCPWASLLLPCSACGAVPSP
Sbjct: 1081 VGPAAVIVLVNMLIGIIVFNKLMARDGISDKSKKQRAGSERCPWASLLLPCSACGAVPSP 1140

Query: 1141 LLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITA 1200
            LLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITA
Sbjct: 1141 LLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITA 1200

Query: 1201 VHCFLRREVQDVVKCQMGVCRADESEDSPDSCKNGQLQILSDFEKDVDLACQTVLFKEVN 1260
            VHCFLRREVQDVVKCQMGVCRADESEDSPDSCKNGQLQILSDFEKDVDLACQTVLFKEVN
Sbjct: 1201 VHCFLRREVQDVVKCQMGVCRADESEDSPDSCKNGQLQILSDFEKDVDLACQTVLFKEVN 1260

Query: 1261 TCNPSTITGTLSRLSLDEDEEPKSCLVGPEGSLSFSPLPGNILVPMAASPGLGEPPPPQE 1320
            TCNPSTITGTLSRLSLDEDEEPKSCLVGPEGSLSFSPLPGNILVPMAASPGLGEPPPPQE
Sbjct: 1261 TCNPSTITGTLSRLSLDEDEEPKSCLVGPEGSLSFSPLPGNILVPMAASPGLGEPPPPQE 1320

Query: 1321 ANPVYMCGEGGLRQLDLTWLRPTEPGSEGDYMVLPRRTLSLQPGGGGGGGEDAPRARPEG 1380
            ANPVYMCGEGGLRQLDLTWLRPTEPGSEGDYMVLPRRTLSLQPGGGGGGGEDAPRARPEG
Sbjct: 1321 ANPVYMCGEGGLRQLDLTWLRPTEPGSEGDYMVLPRRTLSLQPGGGGGGGEDAPRARPEG 1380

Query: 1381 TPRRAAKTVAHTEGYPSFLSVDHSGLGLGPAYGSLQNPYGMTFQPPPPTPSARQVPEPGE 1440
            TPRRAAKTVAHTEGYPSFLSVDHSGLGLGPAYGSLQNPYGMTFQPPPPTPSARQVPEPGE
Sbjct: 1381 TPRRAAKTVAHTEGYPSFLSVDHSGLGLGPAYGSLQNPYGMTFQPPPPTPSARQVPEPGE 1440

Query: 1441 RSRTMPRTVPGSTMKMGSLERKKLRYSDLDFEKVMHTRKRHSELYHELNQKFHTFDRYRS 1500
            RSRTMPRTVPGSTMKMGSLERKKLRYSDLDFEKVMHTRKRHSELYHELNQKFHTFDRYRS
Sbjct: 1441 RSRTMPRTVPGSTMKMGSLERKKLRYSDLDFEKVMHTRKRHSELYHELNQKFHTFDRYRS 1500

Query: 1501 QSTAKREKRWSVSSGGAAERSVCTDKPSPGERPSLSQHRRHQSWSTFKSMTLGSLPPKPR 1560
            QSTAKREKRWSVSSGGAAERSVCTDKPSPGERPSLSQHRRHQSWSTFKSMTLGSLPPKPR
Sbjct: 1501 QSTAKREKRWSVSSGGAAERSVCTDKPSPGERPSLSQHRRHQSWSTFKSMTLGSLPPKPR 1560

Query: 1561 ERLTLHRAAAWEPTEPPDGDFQTEV 1585
            ERLTLHRAAAWEPTEPPDGDFQTEV
Sbjct: 1561 ERLTLHRAAAWEPTEPPDGDFQTEV 1585


>gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens]
          Length = 1522

 Score = 1461 bits (3781), Expect = 0.0
 Identities = 767/1601 (47%), Positives = 1023/1601 (63%), Gaps = 163/1601 (10%)

Query: 40   CSALASGVLYGAFSLQDLFPTIASGCSWTLENPDPTKYSLYLRFNRQEQVCAHFAPRLLP 99
            CS L  GV+YG++S+ ++FP   + C+WTLENPDPTKYS+YL+F++++  C++F+     
Sbjct: 30   CSTLVKGVIYGSYSVSEMFPKNFTNCTWTLENPDPTKYSIYLKFSKKDLSCSNFSLLAYQ 89

Query: 100  LDHYLVNFTCLRPSPEEAVAQAESEVGRPEEEEAEAAAGLELCSGSGPFTFLHFDKNFVQ 159
             DH+         S E+            ++   +  + ++LC+    F FL +DKNF+Q
Sbjct: 90   FDHF---------SHEKI-----------KDLLRKNHSIMQLCNSKNAFVFLQYDKNFIQ 129

Query: 160  LCLSAEPSEAPRLLAPAALAFR-FVEVLLINNNNSSQFTCGVLCRWSEECGRAAG---RA 215
            +     P+  P L        + F E L++N  + SQF C VLC W E C ++      +
Sbjct: 130  I-RRVFPTNFPGLQKKGEEDQKSFFEFLVLNKVSPSQFGCHVLCTWLESCLKSENGRTES 188

Query: 216  CGFAQPGCSCPGEAGAGSTTTTSPGPPAAHTLSNALVPGGPAPPAEADLHSGSSNDLFTT 275
            CG     C+CP   G       S        L+N ++P               + +L TT
Sbjct: 189  CGIMYTKCTCPQHLGEWGIDDQS-----LILLNNVVLP------LNEQTEGCLTQELQTT 237

Query: 276  EM----RYGEEPEEEP-------KVKTQWPRSADEPGL---------YMAQTGDPAAEEW 315
            ++    R  + P +E         +K+Q PRS  E  +         +MAQTG+   EEW
Sbjct: 238  QVCNLTREAKRPPKEEFGMMGDHTIKSQRPRSVHEKRVPQEQADAAKFMAQTGESGVEEW 297

Query: 316  SPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSATCPVHGVWEEWGSWSL 375
            S WS CS+TCGQG QVRTR+CVS PYGT CSGPLRE+R CNN+A CPVHGVWEEW  WSL
Sbjct: 298  SQWSTCSVTCGQGSQVRTRTCVS-PYGTHCSGPLRESRVCNNTALCPVHGVWEEWSPWSL 356

Query: 376  CSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMAACPVEGQWLEWGPWGPCSTSC 435
            CS +CGRG R+R R+C PPQ+GG+ CEGPE   K C++A CPV+GQW EW  W  CS +C
Sbjct: 357  CSFTCGRGQRTRTRSCTPPQYGGRPCEGPETHHKPCNIALCPVDGQWQEWSSWSQCSVTC 416

Query: 436  ANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSKWGPWNAWSLCSKTCDTGW 495
            +NGTQQRSR+C+ A    + C G   ++REC N EC A + +W  W  WS CSK+CD GW
Sbjct: 417  SNGTQQRSRQCTAAAHGGSECRGPWAESRECYNPECTA-NGQWNQWGHWSGCSKSCDGGW 475

Query: 496  QRRFRMCQATGTQGYPCEGTGEEVKPCSEKRCPAFHEMCRDEYVMLMTWKKAAAGEIIYN 555
            +RR R CQ     G  CEGTGEEV+ CSE+RCPA +E+C ++Y+M M WK+  AG++ +N
Sbjct: 476  ERRIRTCQGAVITGQQCEGTGEEVRRCSEQRCPAPYEICPEDYLMSMVWKRTPAGDLAFN 535

Query: 556  KCPPNASGSASRRCLLSAQGVAYWGLPSFARCISHEYRYLYLSLREHLAKGQRMLAGEGM 615
            +CP NA+G+ SRRC LS  GVA+W  PSFARCIS+EYR+L  S++EHLAKGQRMLAG+GM
Sbjct: 536  QCPLNATGTTSRRCSLSLHGVAFWEQPSFARCISNEYRHLQHSIKEHLAKGQRMLAGDGM 595

Query: 616  SQVVRSLQELLARRTYYSGDLLFSVDILRNVTDTFKRATYVPSADDVQRFFQVVSFMVDA 675
            SQV ++L +L  R+ +Y+GDLL SV+ILRNVTDTFKRA+Y+P++D VQ FFQ+VS ++D 
Sbjct: 596  SQVTKTLLDLTQRKNFYAGDLLMSVEILRNVTDTFKRASYIPASDGVQNFFQIVSNLLDE 655

Query: 676  ENKEKWDDAQQVSPGSVHLLRVVEDFIHLVGDALKAFQSSLIVTDNLVISIQREPVSAVS 735
            ENKEKW+DAQQ+ PGS+ L++V+EDFIH+VG  +  FQ+S ++T N+V SIQ+ P ++V 
Sbjct: 656  ENKEKWEDAQQIYPGSIELMQVIEDFIHIVGMGMMDFQNSYLMTGNVVASIQKLPAASVL 715

Query: 736  SDITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSSPGKPATSGAAGSPGRGRGPGTVPPG 795
            +DI FPM+GR+GM DW R+SEDR+ +PK + +      P +S                  
Sbjct: 716  TDINFPMKGRKGMVDWARNSEDRVVIPKSIFT------PVSS------------------ 751

Query: 796  PGHSHQRLLPADPDESSYFVIGAVLYRTLGLILPPPRPPLAVTSRVMTVTVRPPTQPPAE 855
                       + DESS FV+GAVLY+ L LILP  R    + S+++ VT+RP  +   +
Sbjct: 752  ----------KELDESSVFVLGAVLYKNLDLILPTLRNYTVINSKIIVVTIRPEPKT-TD 800

Query: 856  PLITVELSYIINGTTDPHCASWDYSRADASSGDWDTENCQTLETQAAHTRCQCQHLSTFA 915
              + +EL+++ NGT +P+C  WD S+ + S G W T+ C+T+ T A+HT+C C  LSTFA
Sbjct: 801  SFLEIELAHLANGTLNPYCVLWDDSKTNESLGTWSTQGCKTVLTDASHTKCLCDRLSTFA 860

Query: 916  VLAQPPKDLTLELAGSPSVPLVIGCAVSCMALLTLLAIYAAFWRFIKSERSIILLNFCLS 975
            +LAQ P+++ +E +G+PSV L++G  +SC+AL+TL  +YAA WR+I+SERSIIL+NFCLS
Sbjct: 861  ILAQQPREIIMESSGTPSVTLIVGSGLSCLALITLAVVYAALWRYIRSERSIILINFCLS 920

Query: 976  ILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRMRTRLVR 1035
            I++SNILILVGQ++  +K +CT T AFLHFFFL+SFCWVLTEAWQSY+AV G++RTRL+R
Sbjct: 921  IISSNILILVGQTQTHNKSICTTTTAFLHFFFLASFCWVLTEAWQSYMAVTGKIRTRLIR 980

Query: 1036 KRFLCLGWGLPALVVAVSVGFTRTKGYGTSSYCWLSLEGGLLYAFVGPAAVIVLVNMLIG 1095
            KRFLCLGWGLPALVVA SVGFTRTKGYGT  YCWLSLEGGLLYAFVGPAA +VLVNM+IG
Sbjct: 981  KRFLCLGWGLPALVVATSVGFTRTKGYGTDHYCWLSLEGGLLYAFVGPAAAVVLVNMVIG 1040

Query: 1096 IIVFNKLMARDGISDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMASLW 1155
            I+VFNKL++RDGI DK  K RAG    P + L L C+ CG V +  LS+ +A NAMASLW
Sbjct: 1041 ILVFNKLVSRDGILDKKLKHRAGQMSEPHSGLTLKCAKCGVVSTTALSATTASNAMASLW 1100

Query: 1156 SSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREVQDVVKC 1215
            SSCVVLPLLALTWMSAVLAMTD+RS+LFQ LFAVF+S QGFVI  VHC LRREVQD  +C
Sbjct: 1101 SSCVVLPLLALTWMSAVLAMTDKRSILFQILFAVFDSLQGFVIVMVHCILRREVQDAFRC 1160

Query: 1216 QMGVCRADESEDSPDSCKNGQLQILSDFEKDVDLACQTVLFKEVNTCNPSTITGTLSRLS 1275
            ++  C+   + DS  S  NG  QI++DFEKDVD+AC++VL K++  C  +TITGTLSR+S
Sbjct: 1161 RLRNCQDPINADSSSSFPNGHAQIMTDFEKDVDIACRSVLHKDIGPCRAATITGTLSRIS 1220

Query: 1276 LDEDEEPKSCLVGPEGSLSFSPLPGNIL--VPMAASPGLGEPPPPQE-ANP--------- 1323
            L++DEE K     PEG LS+S LPGN++  V +    GL  P    E +NP         
Sbjct: 1221 LNDDEEEKG--TNPEG-LSYSTLPGNVISKVIIQQPTGLHMPMSMNELSNPCLKKENSEL 1277

Query: 1324 ---VYMCGEGGLRQLDLTWLRPTEPGSEGDYMVLPRRTLSLQPGGGGGGGEDAPRARPEG 1380
               VY+C +  LR  D+  + P E   E DY+V+PR +++ QP       E       E 
Sbjct: 1278 RRTVYLCTDDNLRGADMDIVHPQERMMESDYIVMPRSSVNNQPSMKE---ESKMNIGMET 1334

Query: 1381 TPRRAAKTVAHTEGYPSFLS----VDHSGLGLGPAYGSLQNPYGMTFQPPPPTPSARQVP 1436
             P    + + H +  P F      +D   + L       ++   + F+P   T     + 
Sbjct: 1335 LPH---ERLLHYKVNPEFNMNPPVMDQFNMNLEQHLAPQEHMQNLPFEPR--TAVKNFMA 1389

Query: 1437 EPGERSRTMPRTVPGSTMKMGSLERKKLRYSDLDFEKVMHTRKRHSELYHELNQKFHTFD 1496
               + +  + R+  GST+ M SLER+K RYSDLDFEKVMHTRKRH EL+ ELNQKF T D
Sbjct: 1390 SELDDNAGLSRSETGSTISMSSLERRKSRYSDLDFEKVMHTRKRHMELFQELNQKFQTLD 1449

Query: 1497 RYRSQSTAKREKRWSVSSGGAAERSVCTDKPSPGERPSLSQHRRHQSWSTFKS------- 1549
            R+R                     +   + P+P + P          W TFK+       
Sbjct: 1450 RFRD-----------------IPNTSSMENPAPNKNP----------WDTFKNPSEYPHY 1482

Query: 1550 MTLGSLPPKPRERLTLHRAAAWE-----PTEPPDGDFQTEV 1585
             T+  L  + ++ L L R A WE     P +  +GDFQTEV
Sbjct: 1483 TTINVLDTEAKDALEL-RPAEWEKCLNLPLDVQEGDFQTEV 1522


>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo
            sapiens]
          Length = 1584

 Score = 1158 bits (2995), Expect = 0.0
 Identities = 694/1699 (40%), Positives = 915/1699 (53%), Gaps = 261/1699 (15%)

Query: 18   PLLLSVILSLRLATAF-----DPAPSACSALASGVLYGAFSLQDLFPTIASGCSWTLENP 72
            PLLL ++L  R A A       P P  C+ L  G  +G FS   +FP  AS CSWTL NP
Sbjct: 16   PLLLLLLLLGRRARAAAGADAGPGPEPCATLVQGKFFGYFSAAAVFPANASRCSWTLRNP 75

Query: 73   DPTKYSLYLRFNRQEQVCAHFAP-RLLPLDHYLVNFTCLRPSPEEAVAQAESEVGRPEEE 131
            DP +Y+LY++  +    C+     R    D +L +                + +G    +
Sbjct: 76   DPRRYTLYMKVAKAPVPCSGPGRVRTYQFDSFLES--------------TRTYLGVESFD 121

Query: 132  EAEAAAGLELCSGSGPFTFLHFDKNFVQLCLSAEPSE---APRLLAPAALAFRFVEVLLI 188
            E      L LC  S P  FL   K F+Q+     P      PR   P       VE L++
Sbjct: 122  EV-----LRLCDPSAPLAFLQASKQFLQMRRQQPPQHDGLRPRAGPPGPTDDFSVEYLVV 176

Query: 189  NNNNSSQFTCGVLCRWSEEC---------------------GRAAGRACGFAQP-GCSCP 226
             N N S+  C +LCRW + C                     G A G A G   P G  C 
Sbjct: 177  GNRNPSRAACQMLCRWLDACLAGSRSSHPCGIMQTPCACLGGEAGGPAAGPLAPRGDVCL 236

Query: 227  GEAGAGST-----------------------------TTTSPGPPAAHTLSNALVPGGPA 257
             +A AG                               T    G     T +    PG   
Sbjct: 237  RDAVAGGPENCLTSLTQDRGGHGATGGWKLWSLWGECTRDCGGGLQTRTRTCLPAPGVEG 296

Query: 258  PPAEADLHSGS----------------SNDLFTTEMRYGEEPEEEPKVKTQWPRSADEPG 301
               E  L  G                 S  L +T+ R  EE  +E            + G
Sbjct: 297  GGCEGVLEEGRQCNREACGPAGRTSSRSQSLRSTDARRREELGDE----------LQQFG 346

Query: 302  LYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSATC 361
                QTGDPAAEEWSPWSVCS TCG+G Q RTR CVSS Y T CSGPLRE R CNNSA C
Sbjct: 347  FPAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFCVSSSYSTQCSGPLREQRLCNNSAVC 406

Query: 362  PVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMAACP---V 418
            PVHG W+EW  WSLCS +CGRG R R RTC PPQ GG  CEGPE QTK C++A CP   V
Sbjct: 407  PVHGAWDEWSPWSLCSSTCGRGFRDRTRTCRPPQFGGNPCEGPEKQTKFCNIALCPGRAV 466

Query: 419  EGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSKW 478
            +G W EW  W  CS SC+ G QQR+R+C+      A C G   +TR+C   +CP  D KW
Sbjct: 467  DGNWNEWSSWSACSASCSQGRQQRTRECNGPSYGGAECQGHWVETRDCFLQQCPV-DGKW 525

Query: 479  GPWNAWSLCSKTCDTGWQRRFRMCQATGTQGYPCEGTGEEVKPCSEKRCPAFHEMCRDEY 538
              W +W  CS TC  G QRR R+C      G  C+G  +E + C  +RCP  HE+C ++ 
Sbjct: 526  QAWASWGSCSVTCGAGSQRRERVCSGPFFGGAACQGPQDEYRQCGTQRCPEPHEICDEDN 585

Query: 539  VMLMTWKKAAAGEIIYNKCPPNASGSASRRCLLSAQGVAYWGLPSFARCISHEYRYLYLS 598
               + WK+  AGE+   +CP NA+G   RRC L  +G+AYW  P++ RC+S +YR + + 
Sbjct: 586  FGAVIWKETPAGEVAAVRCPRNATGLILRRCELDEEGIAYWEPPTYIRCVSIDYRNIQMM 645

Query: 599  LREHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDLLFSVDILRNVTDTFKRATYVPS 658
             REHLAK QR L GEG+S+V+++L E+    T YSGDLL ++D+LRN+T+ F+RA Y P+
Sbjct: 646  TREHLAKAQRGLPGEGVSEVIQTLVEISQDGTSYSGDLLSTIDVLRNMTEIFRRAYYSPT 705

Query: 659  ADDVQRFFQVVSFMVDAENKEKWDDAQQVSPGSVHLLRVVEDFIHLVGDALKAFQSSLIV 718
              DVQ F Q++S ++  EN++KW++AQ   P +  L R+VEDF+ ++G  +K  + +  V
Sbjct: 706  PGDVQNFVQILSNLLAEENRDKWEEAQLAGPNAKELFRLVEDFVDVIGFRMKDLRDAYQV 765

Query: 719  TDNLVISIQREPVSAVSSDITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSSPGKPATSG 778
            TDNLV+SI + P S  ++DI+FPM+G R   DW +  EDR+ + K V S           
Sbjct: 766  TDNLVLSIHKLPASG-ATDISFPMKGWRATGDWAKVPEDRVTVSKSVFSTGL-------- 816

Query: 779  AAGSPGRGRGPGTVPPGPGHSHQRLLPADPDESSYFVIGAVLYRTLGLILPPPRPPLAVT 838
                                        + DE+S FV+G VLYR LG  L   R    + 
Sbjct: 817  ---------------------------TEADEASVFVVGTVLYRNLGSFLALQRNTTVLN 849

Query: 839  SRVMTVTVRPPTQPPAEPLITVELSYIINGTTDPHCASWDYSRADASS-----GDWDTEN 893
            S+V++VTV+PP +    PL  +E +++ NGTT+  C  WD +   +SS     G W    
Sbjct: 850  SKVISVTVKPPPRSLRTPL-EIEFAHMYNGTTNQTCILWDETDVPSSSAPPQLGPWSWRG 908

Query: 894  CQTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGSPSVPLVIGCAVSCMALLTLLAI 953
            C+T+   A  TRC C  LSTFA+LAQ   D  +E A  PSV L++GC VS + LL L+ I
Sbjct: 909  CRTVPLDALRTRCLCDRLSTFAILAQLSADANMEKATLPSVTLIVGCGVSSLTLLMLVII 968

Query: 954  YAAFWRFIKSERSIILLNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCW 1013
            Y + WR+I+SERS+IL+NFCLSI++SN LIL+GQ++  +K VCT+ AAFLHFFFLSSFCW
Sbjct: 969  YVSVWRYIRSERSVILINFCLSIISSNALILIGQTQTRNKVVCTLVAAFLHFFFLSSFCW 1028

Query: 1014 VLTEAWQSYLAVIGRMRTRLVRKRFLCLGWGLPALVVAVSVGFTRTKGYGTSSYCWLSLE 1073
            VLTEAWQSY+AV G +R RL+RKRFLCLGWGLPALVVA+SVGFT+ KGY T +YCWLSLE
Sbjct: 1029 VLTEAWQSYMAVTGHLRNRLIRKRFLCLGWGLPALVVAISVGFTKAKGYSTMNYCWLSLE 1088

Query: 1074 GGLLYAFVGPAAVIVLVNMLIGIIVFNKLMARDGISDKSKKQRAGSERCPWASLLLPCSA 1133
            GGLLYAFVGPAA +VLVNM+IGI+VFNKL+++DGI+DK  K+RAG               
Sbjct: 1089 GGLLYAFVGPAAAVVLVNMVIGILVFNKLVSKDGITDKKLKERAG--------------- 1133

Query: 1134 CGAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSA 1193
                              ASLWSSCVVLPLLALTWMSAVLA+TDRRS LFQ LFAVF+S 
Sbjct: 1134 ------------------ASLWSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSL 1175

Query: 1194 QGFVITAVHCFLRREVQDVVKCQMGVCRADESEDSPDSCKNGQLQILSDFEKDVDLACQT 1253
            +GFVI  VHC LRREVQD VKC++   + + + DS  S +NG  Q+++DFEKDVDLAC++
Sbjct: 1176 EGFVIVMVHCILRREVQDAVKCRVVDRQEEGNGDSGGSFQNGHAQLMTDFEKDVDLACRS 1235

Query: 1254 VLFKEVNTCNPSTITGTLSRLSLDEDEEPK-SCLVGPEGSLSFSPLPGNI-LVPMAASPG 1311
            VL K++  C  +TITGTL R SL E+E+ K +   GP    +F+ LP N+  + +  SP 
Sbjct: 1236 VLNKDIAACRTATITGTLKRPSLPEEEKLKLAHAKGP--PTNFNSLPANVSKLHLHGSPR 1293

Query: 1312 LGEPPPP-----------QEANPVYMCGEGGL-RQLDLTWLRPTEPGSEGDYMVLPRRTL 1359
                P P            +A      G+G + ++LD    R  E   +  Y++LP  T 
Sbjct: 1294 YPGGPLPDFPNHSLTLKRDKAPKSSFVGDGDIFKKLDSELSRAQEKALDTSYVILPTATA 1353

Query: 1360 SLQPGGGGGGGEDAPRARPEGT---PRRAAKTVAHTEGYP-SFLSVDHSGLGLGPAYGSL 1415
            +L+P          P+  P+ +    +     + H    P + L          P+ G  
Sbjct: 1354 TLRP---------KPKEEPKYSIHIDQMPQTRLIHLSTAPEASLPARSPPSRQPPSGGPP 1404

Query: 1416 QNPYGMTFQPPPPTPSARQVP---------------EPGE-RSRTMPRTVPG------ST 1453
            + P      PPPP P   Q P               +PGE  +   P T P       +T
Sbjct: 1405 EAPPAQPPPPPPPPPPPPQQPLPPPPNLEPAPPSLGDPGEPAAHPGPSTGPSTKNENVAT 1464

Query: 1454 MKMGSLERKKLRYSDLDFEKVMHTRKRHSELYHELNQKFHTFDRYRSQSTAKREKRWSVS 1513
            + + SLER+K RY++LDFEK+MHTRKRH +++ +LN+K         Q  A+++K   + 
Sbjct: 1465 LSVSSLERRKSRYAELDFEKIMHTRKRHQDMFQDLNRKL--------QHAAEKDKE-VLG 1515

Query: 1514 SGGAAERSVCTDKPSPGERPSLSQHRRHQSWSTFKSMTLGSLPPKPRERLTLHRAAAWE- 1572
                 E+     + +P +RP  S  + H +  T+    L  L P P E     R+  WE 
Sbjct: 1516 PDSKPEK-----QQTPNKRPWESLRKAHGT-PTWVKKELEPLQPSPLEL----RSVEWER 1565

Query: 1573 --PTEPPDG----DFQTEV 1585
               T P  G    D QTEV
Sbjct: 1566 SGATIPLVGQDIIDLQTEV 1584


>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
            sapiens]
          Length = 3014

 Score =  212 bits (539), Expect = 3e-54
 Identities = 223/960 (23%), Positives = 388/960 (40%), Gaps = 148/960 (15%)

Query: 316  SPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSATCPVHGVWEEW----- 370
            +P +V +L     L+VR +       G     P   + PC  ++ C  H  WE++     
Sbjct: 1849 TPTNVATLNMNNALKVRVKD------GCDVDDPCTSS-PCPPNSRC--HDAWEDYSCVCD 1899

Query: 371  -GSWSL-CSRSCGRGSRSRMRTCV--PPQHGGKACE------GPELQTKLCSMAACPVEG 420
             G   + C  +C       M  CV  P    G  CE      GP  + KL      P   
Sbjct: 1900 KGYLGINCVDACHLNPCENMGACVRSPGSPQGYVCECGPSHYGPYCENKL----DLPCPR 1955

Query: 421  QWLEWGP--WGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSKW 478
             W  WG    GPC  + + G      K +            L     C   +C    S  
Sbjct: 1956 GW--WGNPVCGPCHCAVSKGFDPDCNKTNGQCQCKENYYKLLAQDT-CLPCDCFPHGSH- 2011

Query: 479  GPWNAWSLCSKTCDTGWQRRFRMCQATGTQGYPCEGTGEEVKPCSEKRCPAFHEMCRDEY 538
                     S+TCD    +        G Q   C+    EV       C   +  C   +
Sbjct: 2012 ---------SRTCDMATGQCACKPGVIGRQCNRCDNPFAEVTTLG---CEVIYNGCPKAF 2059

Query: 539  VMLMTWKKAAAGEIIYNKCPPNASGSASRRCLLSAQGVAYWGLPSFARCISHEYRYLYLS 598
               + W +   G+     CP  + G+A R C     G   W  P    C +  +  L  +
Sbjct: 2060 EAGIWWPQTKFGQPAAVPCPKGSVGNAVRHC----SGEKGWLPPELFNCTTISFVDLR-A 2114

Query: 599  LREHLAKGQRMLAGEGMSQVVRSLQELLARR-TYYSGDLLFSVDILRNVT--DTFKRATY 655
            + E L++ +  + G    Q+VR+L+       T +  D+  +  +L +V   +++++   
Sbjct: 2115 MNEKLSRNETQVDGARALQLVRALRSATQHTGTLFGNDVRTAYQLLGHVLQHESWQQGFD 2174

Query: 656  VPSADDVQRFFQVV---SFMVDAENKEKWDDAQQVSPGSVHLLRVVEDFIHLVGDALKA- 711
            + +  D      V+   S ++    +  W+  Q+   G+  LLR +E +   V   ++  
Sbjct: 2175 LAATQDADFHEDVIHSGSALLAPATRAAWEQIQRSEGGTAQLLRRLEGYFSNVARNVRRT 2234

Query: 712  -FQSSLIVTDNLVISIQREPVSAVSSDITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSS 770
              +  +IVT N+++        AV     F   G R  +    H E     P+E+ S  S
Sbjct: 2235 YLRPFVIVTANMIL--------AVDIFDKFNFTGARVPRFDTIHEE----FPRELESSVS 2282

Query: 771  -------PGKPATSGAAGSPGRGRGPGTVPPGPGHSHQRLLPA---DPDESSYFVIGAVL 820
                   P +          GR   P T  PGPG   +  +      PD++  F +  V+
Sbjct: 2283 FPADFFRPPEEKEGPLLRPAGRRTTPQTTRPGPGTEREAPISRRRRHPDDAGQFAVALVI 2342

Query: 821  -YRTLGLILPP-----------PRPPLAVTSRVMTVTVRP--PTQPPAEPLITVELSYI- 865
             YRTLG +LP            P  P+  T  V T+      P   P E  + VE + + 
Sbjct: 2343 IYRTLGQLLPERYDPDRRSLRLPHRPIINTPMVSTLVYSEGAPLPRPLERPVLVEFALLE 2402

Query: 866  INGTTDPHCASWDYSRADASSGDWDTENCQTLETQAAHTRCQCQHLSTFAVL-----AQP 920
            +   T P C  W++S A   +G W    C+ L     H  CQC H ++FAVL      + 
Sbjct: 2403 VEERTKPVCVFWNHSLAVGGTGGWSARGCELLSRNRTHVACQCSHTASFAVLMDISRREN 2462

Query: 921  PKDLTLELAGSPSVPLVIGCAVSCMALLTLLAIYAAFWRFIKSERSIILLNFCLSILASN 980
             + L L++    +V L +   +    LL+L+       R ++S    I  +  +++  S 
Sbjct: 2463 GEVLPLKIVTYAAVSLSLAALLVAFVLLSLV-------RMLRSNLHSIHKHLAVALFLSQ 2515

Query: 981  ILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWVLTEAWQSY--LAVIGRMRTRLVRKRF 1038
            ++ ++G ++  +  +CT+ A  LH+ ++S+F W L E+   Y  L  +  + T  +R  +
Sbjct: 2516 LVFVIGINQTENPFLCTVVAILLHYIYMSTFAWTLVESLHVYRMLTEVRNIDTGPMRFYY 2575

Query: 1039 LCLGWGLPALVVAVSVGFTRTKGYGTSSYCWLSLEGGLLYAFVGPAAVIVLVNMLIGIIV 1098
            + +GWG+PA+V  ++VG    +GYG   +CWLSL+  L+++F GP   ++++N +  ++ 
Sbjct: 2576 V-VGWGIPAIVTGLAVGLD-PQGYGNPDFCWLSLQDTLIWSFAGPIGAVIIINTVTSVLS 2633

Query: 1099 FNKLMARDGISDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMASLWSSC 1158
                     +S + K    G                             +  ++ L ++ 
Sbjct: 2634 AK-------VSCQRKHHYYGK----------------------------KGIVSLLRTAF 2658

Query: 1159 VVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREVQDVVKCQMG 1218
            ++L L++ TW+  +LA+ +R ++ F  LFA+F+  QG  +   HC L +EV+  +K  +G
Sbjct: 2659 LLLLLISATWLLGLLAV-NRDALSFHYLFAIFSGLQGPFVLLFHCVLNQEVRKHLKGVLG 2717


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score =  198 bits (504), Expect = 3e-50
 Identities = 96/224 (42%), Positives = 126/224 (56%), Gaps = 11/224 (4%)

Query: 314  EWSPWSVCSLTCGQGLQVRTRSC---VSSPYGTLCSGPLRETRPCNNSATCPVHGVWEEW 370
            +WS W  CS+TCG+G+Q R+R C   + +  G  C G   E R C N   CPV G W EW
Sbjct: 4534 QWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKP-CPVDGSWSEW 4592

Query: 371  GSWSLCSRSCGRGSRSRMRTCVPP--QHGGKACEGPELQTKLCSMAACPVEGQWLEWGPW 428
              W  C+RSCGRG+++R RTC  P  QHGG+ CEG  ++  +C++  CPV G W  W PW
Sbjct: 4593 SLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGAWSAWQPW 4652

Query: 429  GPCSTSCANGTQQRSRKCSVAGPAW--ATCTGALTDTRECSNLECPATDSKWGPWNAWSL 486
            G CS SC  GTQ R+R C+   PA+  + C GA T  + C+   CP    KW  W +WS 
Sbjct: 4653 GTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP-IHGKWATWASWSA 4711

Query: 487  CSKTCDTGWQRRFRMCQATGTQ--GYPCEGTGEEVKPCSEKRCP 528
            CS +C  G ++R R C     Q  G  CEG+  +   C+   CP
Sbjct: 4712 CSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCP 4755



 Score =  189 bits (481), Expect = 1e-47
 Identities = 88/229 (38%), Positives = 119/229 (51%), Gaps = 11/229 (4%)

Query: 309  DPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSPY---GTLCSGPLRETRPCNNSATCPVHG 365
            D +  EWS W  C+ +CG+G Q RTR+C +      G  C G   E   CN    CPVHG
Sbjct: 4586 DGSWSEWSLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEIIMCN-IRPCPVHG 4644

Query: 366  VWEEWGSWSLCSRSCGRGSRSRMRTC--VPPQHGGKACEGPELQTKLCSMAACPVEGQWL 423
             W  W  W  CS SCG+G+++R R C   PP  GG  C+G E Q ++C+   CP+ G+W 
Sbjct: 4645 AWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCPIHGKWA 4704

Query: 424  EWGPWGPCSTSCANGTQQRSRKCSVAGPAWA--TCTGALTDTRECSNLECPATDSKWGPW 481
             W  W  CS SC  G +QR+R CS   P +    C G+   +  C++  CP T   W PW
Sbjct: 4705 TWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCP-THGNWSPW 4763

Query: 482  NAWSLCSKTCDTGWQRRFRMCQ--ATGTQGYPCEGTGEEVKPCSEKRCP 528
            + W  CS+TC+ G  RR+R C        G  C G   +++ C+   CP
Sbjct: 4764 SGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4812



 Score =  187 bits (474), Expect = 9e-47
 Identities = 88/234 (37%), Positives = 118/234 (50%), Gaps = 11/234 (4%)

Query: 315  WSPWSVCSLTCGQGLQVRTRSCVSSPY---GTLCSGPLRETRPCNNSATCPVHGVWEEWG 371
            W PW  CS +CG+G Q R R C + P    G+ C G   + + CN    CP+HG W  W 
Sbjct: 4649 WQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNER-NCPIHGKWATWA 4707

Query: 372  SWSLCSRSCGRGSRSRMRTCVPP--QHGGKACEGPELQTKLCSMAACPVEGQWLEWGPWG 429
            SWS CS SCG G+R R R C  P  Q+GG+ CEG ++Q+  C+   CP  G W  W  WG
Sbjct: 4708 SWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTHGNWSPWSGWG 4767

Query: 430  PCSTSCANGTQQRSRKCSVAGPA--WATCTGALTDTRECSNLECPATDSKWGPWNAWSLC 487
             CS +C  G  +R R C    P+     C G  +  + C+   CP  D  WG W++WS C
Sbjct: 4768 TCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCPV-DGSWGSWHSWSQC 4826

Query: 488  SKTCDTGWQRRFRMCQ--ATGTQGYPCEGTGEEVKPCSEKRCPAFHEMCRDEYV 539
            S +C  G + R R+C        G PC G   +V  C+ + CP   +  R   +
Sbjct: 4827 SASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPGGPQRARGSVI 4880



 Score =  132 bits (332), Expect = 3e-30
 Identities = 60/172 (34%), Positives = 86/172 (50%), Gaps = 7/172 (4%)

Query: 363  VHGVWEEWGSWSLCSRSCGRGSRSRMRTCVP--PQHGGKACEGPELQTKLCSMAACPVEG 420
            VHG + +W +W  CS +CG+G + R R C    P +GGK C+G +L+ + C    CPV+G
Sbjct: 4528 VHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDG 4587

Query: 421  QWLEWGPWGPCSTSCANGTQQRSRKCS--VAGPAWATCTGALTDTRECSNLECPATDSKW 478
             W EW  W  C+ SC  G Q R+R C+          C G   +   C+   CP     W
Sbjct: 4588 SWSEWSLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEIIMCNIRPCP-VHGAW 4646

Query: 479  GPWNAWSLCSKTCDTGWQRRFRMCQ--ATGTQGYPCEGTGEEVKPCSEKRCP 528
              W  W  CS++C  G Q R R+C        G  C+G   +++ C+E+ CP
Sbjct: 4647 SAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4698


>gi|163792198 latrophilin 3 precursor [Homo sapiens]
          Length = 1469

 Score =  186 bits (471), Expect = 2e-46
 Identities = 184/747 (24%), Positives = 315/747 (42%), Gaps = 120/747 (16%)

Query: 521  PCSEKRCPAFHEMCRDEYVMLMTWKKAAAGEIIYNKCPPNASGSASRRCLLSAQGVAYWG 580
            P +  + PA  E C       + W K   G+I    CP    G ++  CL +  G+    
Sbjct: 485  PSASSQIPALEESCEAVEAREIMWFKTRQGQIAKQPCPAGTIGVSTYLCL-APDGIWDPQ 543

Query: 581  LPSFARCISHEYRYLYLSLREHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDLLFSV 640
             P  + C S    ++           Q++ +GE  + + R L E   R    +GD+ +SV
Sbjct: 544  GPDLSNCSSPWVNHIT----------QKLKSGETAANIARELAEQ-TRNHLNAGDITYSV 592

Query: 641  ----------DI-LRNVT----DTFKRATYVPSADD------VQRFFQVVSFMVDAENKE 679
                      D+ LRN+T    D+  R+       +      VQ   + V+ ++  +   
Sbjct: 593  RAMDQLVGLLDVQLRNLTPGGKDSAARSLNKLQKRERSCRAYVQAMVETVNNLLQPQALN 652

Query: 680  KWDD---AQQVSPGSVHLLRVVEDFIHLVGDALKAFQSSLIVTDNLVISIQREPVSAVSS 736
             W D   + Q+   ++ LL  VE+   ++ D L         TDN+ + + R        
Sbjct: 653  AWRDLTTSDQLRAATM-LLHTVEESAFVLADNLLKTDIVRENTDNIKLEVARLSTEGNLE 711

Query: 737  DITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSSPGKPATSGAAGSPGRGRGPGTVPPGP 796
            D+ FP     G                  + LS+     T    G  G  R    +    
Sbjct: 712  DLKFPENMGHG----------------STIQLSAN----TLKQNGRNGEIRVAFVL---- 747

Query: 797  GHSHQRLLPADPDESSYFVIGAVLYRTLGLILPPPRPPLAVTSRVMTVTVRPPTQPP--- 853
               +  L P    E++   +G     T   ++        V S V+T  +          
Sbjct: 748  ---YNNLGPYLSTENASMKLGTEALSTNHSVI--------VNSPVITAAINKEFSNKVYL 796

Query: 854  AEPLI-TVELSYIINGTTDPHCASWDYSRADASSGDWDTENCQTLETQAAHTRCQCQHLS 912
            A+P++ TV+         +P+C+ W YS+    +G W T+ C+ L T   HT C C HL+
Sbjct: 797  ADPVVFTVKHIKQSEENFNPNCSFWSYSKR-TMTGYWSTQGCRLLTTNKTHTTCSCNHLT 855

Query: 913  TFAVL--------AQPPKDLTLELAGSPSVPLVIGCAVSCMALLTLLAIYAAFWRFIKSE 964
             FAVL        +    DL L++     + L + C + C+           F+R ++S+
Sbjct: 856  NFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVCLLICIFTF-------CFFRGLQSD 908

Query: 965  RSIILLNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWVLTEAWQSYLA 1024
            R+ I  N C+S+  + +L L+G +R      C + AA LHFFFL++F W+  E  Q Y+ 
Sbjct: 909  RNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIM 968

Query: 1025 VIGRMRTRLVRKR-FLCLGWGLPALVVAVSVGFTRTKGYGTSSYCWLSLEGGLLYAFVGP 1083
            ++    +   R++ F  +G+G+PAL+VAVS      + YGT   CWL L+   +++F+GP
Sbjct: 969  LVEVFESEHSRRKYFYLVGYGMPALIVAVSAA-VDYRSYGTDKVCWLRLDTYFIWSFIGP 1027

Query: 1084 AAVIVLVNMLIGIIVFNKLMARDGISDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLS 1143
            A +I+++N++   I   K+                       ++L P S C       ++
Sbjct: 1028 ATLIIMLNVIFLGIALYKMFHH-------------------TAILKPESGC----LDNIN 1064

Query: 1144 SASARNAMAS-LWSSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVH 1202
                R  + S +  +  +L LL LTW   ++ + +  +V+   LF +FNS QG  I   H
Sbjct: 1065 YEDNRPFIKSWVIGAIALLCLLGLTWAFGLMYINE-STVIMAYLFTIFNSLQGMFIFIFH 1123

Query: 1203 CFLRREV-QDVVKCQMGVCRADESEDS 1228
            C L+++V ++  KC    C + +S +S
Sbjct: 1124 CVLQKKVRKEYGKCLRTHCCSGKSTES 1150


>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
            sapiens]
          Length = 2923

 Score =  172 bits (436), Expect = 2e-42
 Identities = 213/906 (23%), Positives = 346/906 (38%), Gaps = 125/906 (13%)

Query: 354  PCNNSATCPVHGVWE-EWGSWSL----------CSRSCGRGSRSRMRTCV--PPQHGGKA 400
            PC+++  CP +     +W S+S           C+  C          C   P    G  
Sbjct: 1796 PCDSNP-CPANSYCSNDWDSYSCSCDPGYYGDNCTNVCDLNPCEHQSVCTRKPSAPHGYT 1854

Query: 401  CE------GPELQTKLCSMAACPVEGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWA 454
            CE      GP  +T++      P    W      GPC+   + G      K S       
Sbjct: 1855 CECPPNYLGPYCETRIDQ----PCPRGWWGHPTCGPCNCDVSKGFDPDCNKTS------G 1904

Query: 455  TCTGALTDTRECSNLECPATDSKWGPWNAWSLCSKTCDTGWQRRFRMCQAT-GTQGYPCE 513
             C       R   +  C   D     +   SL S+ CD         C    G  G  C+
Sbjct: 1905 ECHCKENHYRPPGSPTCLLCDC----YPTGSL-SRVCDP----EDGQCPCKPGVIGRQCD 1955

Query: 514  GTGEEVKPCSEKRCPAFHEMCRDEYVMLMTWKKAAAGEIIYNKCPPNASGSASRRCLLSA 573
                     +   C   ++ C       + W +   G      CP  + G+A R C    
Sbjct: 1956 RCDNPFAEVTTNGCEVNYDSCPRAIEAGIWWPRTRFGLPAAAPCPKGSFGTAVRHC---- 2011

Query: 574  QGVAYWGLPSFARCISHEYRYLYLSLREHLAKGQRMLAGEGMSQVVRSLQELLARRT--Y 631
                 W  P+   C S  +  L     E L + +  L   G SQ +  L     + T  Y
Sbjct: 2012 DEHRGWLPPNLFNCTSITFSELK-GFAERLQRNESGL-DSGRSQQLALLLRNATQHTAGY 2069

Query: 632  YSGDLLFSVDILRNVT--DTFKRATYVPSADDV---QRFFQVVSFMVDAENKEKWDDAQQ 686
            +  D+  +  +   +   ++ +R   + +  DV   +   +V S ++D  NK  W+  QQ
Sbjct: 2070 FGSDVKVAYQLATRLLAHESTQRGFGLSATQDVHFTENLLRVGSALLDTANKRHWELIQQ 2129

Query: 687  VSPGSVHLLRVVEDFIHLVGDALKAFQSS--LIVTDNLVISIQREPVSAVSSDITFPMRG 744
               G+  LL+  E +   +   ++    S   IVT N+VIS+ R      +         
Sbjct: 2130 TEGGTAWLLQHYEAYASALAQNMRHTYLSPFTIVTPNIVISVVRLDKGNFAGAKLPRYEA 2189

Query: 745  RRGMKDWVRHSEDRLFLPKEVLSLSSPG-KPATSGAAGSPGRGRGPGTVPPGPGHSHQRL 803
             RG +      E  + LP+ V   + P  +PA       PG  + P  +        QR 
Sbjct: 2190 LRGEQP--PDLETTVILPESVFRETPPVVRPA------GPGEAQEPEELA-----RRQRR 2236

Query: 804  LPADPDESSYFVIGAVLYRTLGLILP----PPRPPLAVTSR------VMTVTVRPPTQPP 853
             P      +  V   ++YRTL  +LP    P +  L V  R      V++++V    +  
Sbjct: 2237 HPELSQGEA--VASVIIYRTLAGLLPHNYDPDKRSLRVPKRPIINTPVVSISVHDDEELL 2294

Query: 854  AEPL---ITVELSYI-INGTTDPHCASWDYSRADASSGDWDTENCQTLETQAAHTRCQCQ 909
               L   +TV+   +     T P C  W++S   + +G W    C+ +    +H  CQC 
Sbjct: 2295 PRALDKPVTVQFRLLETEERTKPICVFWNHSILVSGTGGWSARGCEVVFRNESHVSCQCN 2354

Query: 910  HLSTFAVLAQPPKDLTLELAGSPSVPLVIGCAVSCMALLTLLAIYAAFWRFIKSERSIIL 969
            H+++FAVL    +    E+   P   L        +A L L   +    R ++S +  I 
Sbjct: 2355 HMTSFAVLMDVSRRENGEIL--PLKTLTYVALGVTLAALLLTFFFLTLLRILRSNQHGIR 2412

Query: 970  LNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRM 1029
             N   ++  + ++ L+G ++      CT+ A  LHF +L +F W L EA   Y A+    
Sbjct: 2413 RNLTAALGLAQLVFLLGINQADLPFACTVIAILLHFLYLCTFSWALLEALHLYRALTEVR 2472

Query: 1030 RTRLVRKRF-LCLGWGLPALVVAVSVGFTRTKGYGTSSYCWLSLEGGLLYAFVGPAAVIV 1088
                   RF   LGWG+PA +  ++VG    +GYG   +CWLS+   L+++F GP A  V
Sbjct: 2473 DVNTGPMRFYYMLGWGVPAFITGLAVGLD-PEGYGNPDFCWLSIYDTLIWSFAGPVAFAV 2531

Query: 1089 LVNMLIGIIVFNKLMARDGISDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASAR 1148
             +++ + I+      A          QR G E+                          +
Sbjct: 2532 SMSVFLYILAARASCA---------AQRQGFEK--------------------------K 2556

Query: 1149 NAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRRE 1208
              ++ L  S  VL LL+ TW+ A+L++ +  ++LF  LFA  N  QG  I   +  L +E
Sbjct: 2557 GPVSGLQPSFAVLLLLSATWLLALLSV-NSDTLLFHYLFATCNCIQGPFIFLSYVVLSKE 2615

Query: 1209 VQDVVK 1214
            V+  +K
Sbjct: 2616 VRKALK 2621


>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
          Length = 1474

 Score =  159 bits (402), Expect = 2e-38
 Identities = 164/728 (22%), Positives = 293/728 (40%), Gaps = 142/728 (19%)

Query: 534  CRDEYVMLMTWKKAAAGEIIYNKCPPNASGSASRRCLLSAQGVAYWGLPSFARCISHEYR 593
            C    V  + W     G ++   CP    G AS +CL  A G+     P  + C S    
Sbjct: 480  CEPREVRRVQWPATQQGMLVERPCPKGTRGIASFQCL-PALGLWNPRGPDLSNCTSPWVN 538

Query: 594  YLYLSLREHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDLLFSVDILRNVTDTFK-- 651
             +           Q++ +GE  + +   L     R + Y+GD+  SV ++  + D     
Sbjct: 539  QV----------AQKIKSGENAANIASELARH-TRGSIYAGDVSSSVKLMEQLLDILDAQ 587

Query: 652  ----RATYVPSA---------------DDVQRFFQVVSFMVDAENKEKWDD---AQQVSP 689
                R     SA               D ++   + V  ++  E  E W D    +QV  
Sbjct: 588  LQALRPIERESAGKNYNKMHKRERTCKDYIKAVVETVDNLLRPEALESWKDMNATEQVHT 647

Query: 690  GSVHLLRVVEDFIHLVGDALKAFQSSLIVTDNLVISIQREPVSAVSSDITFPMR------ 743
             ++ LL V+E+   L+ D ++     L   +N+V+ +          ++ FP        
Sbjct: 648  ATM-LLDVLEEGAFLLADNVREPARFLAAKENVVLEVTVLNTEGQVQELVFPQEEYPRKN 706

Query: 744  ----GRRGMKDWVRHSEDRL-FLPKEVLSLSSPGKPATSGAAGSPGRGRGPGTVPPGPGH 798
                  + +K   R+   ++ F+    L L    + AT   AG  G        P GPG 
Sbjct: 707  SIQLSAKTIKQNSRNGVVKVVFILYNNLGLFLSTENATVKLAGEAG--------PGGPGG 758

Query: 799  SHQRLLPADPDESSYFVIGAVLYRTLGLILPPPRPPLAVTSRVMTVTVRPPTQPP--AEP 856
            +                                   L V S+V+  ++   +      +P
Sbjct: 759  AS----------------------------------LVVNSQVIAASINKESSRVFLMDP 784

Query: 857  LITVELSYIINGTTDPHCASWDYSRADASSGDWDTENCQTLETQAAHTRCQCQHLSTFAV 916
            +I            + +C+ W+YS   +  G W T+ C+ +E+   HT C C HL+ FAV
Sbjct: 785  VIFTVAHLEDKNHFNANCSFWNYSER-SMLGYWSTQGCRLVESNKTHTTCACSHLTNFAV 843

Query: 917  LAQPPK-------DLTLELAGSPSVPLVIGCAVSCMALLTLLAIYAAFWRFIKSERSIIL 969
            L    +       +L L      SV   +G  +S + L   ++ +  F R ++++R+ I 
Sbjct: 844  LMAHREIYQGRINELLL------SVITWVGIVISLVCLAICISTFC-FLRGLQTDRNTIH 896

Query: 970  LNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRM 1029
             N C+++  + +L LVG  +   +  C + A  LH+FFL++F W+  E    YL ++   
Sbjct: 897  KNLCINLFLAELLFLVGIDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVF 956

Query: 1030 RTRLVRKRFLCL-GWGLPALVVAVSVGFTRTKGYGTSSYCWLSLEGGLLYAFVGPAAVIV 1088
             +   R ++  L G+  PALVV ++      + YGT   CWL ++   +++F+GP + ++
Sbjct: 957  ESEYSRTKYYYLGGYCFPALVVGIAAAID-YRSYGTEKACWLRVDNYFIWSFIGPVSFVI 1015

Query: 1089 LVNMLIGIIVFNKLMARDGISDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASAR 1148
            +VN++  ++  +K++                     +S+L P             S+   
Sbjct: 1016 VVNLVFLMVTLHKMIRS-------------------SSVLKP------------DSSRLD 1044

Query: 1149 NAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRRE 1208
            N  +    +  +L LL LTW   +L   ++ SV+   LF  FN+ QG  I   HC L+++
Sbjct: 1045 NIKSWALGAIALLFLLGLTWAFGLL-FINKESVVMAYLFTTFNAFQGVFIFVFHCALQKK 1103

Query: 1209 V-QDVVKC 1215
            V ++  KC
Sbjct: 1104 VHKEYSKC 1111


>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
          Length = 1469

 Score =  159 bits (402), Expect = 2e-38
 Identities = 164/728 (22%), Positives = 293/728 (40%), Gaps = 142/728 (19%)

Query: 534  CRDEYVMLMTWKKAAAGEIIYNKCPPNASGSASRRCLLSAQGVAYWGLPSFARCISHEYR 593
            C    V  + W     G ++   CP    G AS +CL  A G+     P  + C S    
Sbjct: 475  CEPREVRRVQWPATQQGMLVERPCPKGTRGIASFQCL-PALGLWNPRGPDLSNCTSPWVN 533

Query: 594  YLYLSLREHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDLLFSVDILRNVTDTFK-- 651
             +           Q++ +GE  + +   L     R + Y+GD+  SV ++  + D     
Sbjct: 534  QV----------AQKIKSGENAANIASELARH-TRGSIYAGDVSSSVKLMEQLLDILDAQ 582

Query: 652  ----RATYVPSA---------------DDVQRFFQVVSFMVDAENKEKWDD---AQQVSP 689
                R     SA               D ++   + V  ++  E  E W D    +QV  
Sbjct: 583  LQALRPIERESAGKNYNKMHKRERTCKDYIKAVVETVDNLLRPEALESWKDMNATEQVHT 642

Query: 690  GSVHLLRVVEDFIHLVGDALKAFQSSLIVTDNLVISIQREPVSAVSSDITFPMR------ 743
             ++ LL V+E+   L+ D ++     L   +N+V+ +          ++ FP        
Sbjct: 643  ATM-LLDVLEEGAFLLADNVREPARFLAAKENVVLEVTVLNTEGQVQELVFPQEEYPRKN 701

Query: 744  ----GRRGMKDWVRHSEDRL-FLPKEVLSLSSPGKPATSGAAGSPGRGRGPGTVPPGPGH 798
                  + +K   R+   ++ F+    L L    + AT   AG  G        P GPG 
Sbjct: 702  SIQLSAKTIKQNSRNGVVKVVFILYNNLGLFLSTENATVKLAGEAG--------PGGPGG 753

Query: 799  SHQRLLPADPDESSYFVIGAVLYRTLGLILPPPRPPLAVTSRVMTVTVRPPTQPP--AEP 856
            +                                   L V S+V+  ++   +      +P
Sbjct: 754  AS----------------------------------LVVNSQVIAASINKESSRVFLMDP 779

Query: 857  LITVELSYIINGTTDPHCASWDYSRADASSGDWDTENCQTLETQAAHTRCQCQHLSTFAV 916
            +I            + +C+ W+YS   +  G W T+ C+ +E+   HT C C HL+ FAV
Sbjct: 780  VIFTVAHLEDKNHFNANCSFWNYSER-SMLGYWSTQGCRLVESNKTHTTCACSHLTNFAV 838

Query: 917  LAQPPK-------DLTLELAGSPSVPLVIGCAVSCMALLTLLAIYAAFWRFIKSERSIIL 969
            L    +       +L L      SV   +G  +S + L   ++ +  F R ++++R+ I 
Sbjct: 839  LMAHREIYQGRINELLL------SVITWVGIVISLVCLAICISTFC-FLRGLQTDRNTIH 891

Query: 970  LNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRM 1029
             N C+++  + +L LVG  +   +  C + A  LH+FFL++F W+  E    YL ++   
Sbjct: 892  KNLCINLFLAELLFLVGIDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVF 951

Query: 1030 RTRLVRKRFLCL-GWGLPALVVAVSVGFTRTKGYGTSSYCWLSLEGGLLYAFVGPAAVIV 1088
             +   R ++  L G+  PALVV ++      + YGT   CWL ++   +++F+GP + ++
Sbjct: 952  ESEYSRTKYYYLGGYCFPALVVGIAAAID-YRSYGTEKACWLRVDNYFIWSFIGPVSFVI 1010

Query: 1089 LVNMLIGIIVFNKLMARDGISDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASAR 1148
            +VN++  ++  +K++                     +S+L P             S+   
Sbjct: 1011 VVNLVFLMVTLHKMIRS-------------------SSVLKP------------DSSRLD 1039

Query: 1149 NAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRRE 1208
            N  +    +  +L LL LTW   +L   ++ SV+   LF  FN+ QG  I   HC L+++
Sbjct: 1040 NIKSWALGAIALLFLLGLTWAFGLL-FINKESVVMAYLFTTFNAFQGVFIFVFHCALQKK 1098

Query: 1209 V-QDVVKC 1215
            V ++  KC
Sbjct: 1099 VHKEYSKC 1106


>gi|148806925 EGF, latrophilin and seven transmembrane domain
            containing 1 [Homo sapiens]
          Length = 690

 Score =  158 bits (400), Expect = 3e-38
 Identities = 122/387 (31%), Positives = 186/387 (48%), Gaps = 56/387 (14%)

Query: 837  VTSRVMTVTV--RPPTQPPAEPLITVELSYIINGTTDPH---CASWDYSRADASSGDWDT 891
            V S V++V++   PPT    E  IT  LS+     TD +   CA W+YS  D  +G W +
Sbjct: 331  VISSVISVSMSSNPPTLYELEK-ITFTLSH--RKVTDRYRSLCAFWNYS-PDTMNGSWSS 386

Query: 892  ENCQTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGSPSVPLVIGCAVSCMALLTLL 951
            E C+   +   HT C+C HL+ FA+L      + ++     +    +G  +S   L+ L 
Sbjct: 387  EGCELTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYNILTRITQLGIIIS---LICLA 443

Query: 952  AIYAAFWRF--IKSERSIILLNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLS 1009
                 FW F  I+S R+ I  N C S+  + ++ LVG +   +K  C++ A  LH+FFL+
Sbjct: 444  ICIFTFWFFSEIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLA 503

Query: 1010 SFCWVLTEAWQSYLAVIGRMRTR-LVRKRFLCLGWGLPALVVAVSVGFTRTKG---YGTS 1065
            +F W+  E    YL V+G +  +  + K F   G+  PA+V    VGF+   G   YGT+
Sbjct: 504  AFAWMCIEGIHLYLIVVGVIYNKGFLHKNFYIFGYLSPAVV----VGFSAALGYRYYGTT 559

Query: 1066 SYCWLSLEGGLLYAFVGPAAVIVLVNML-IGIIVFNKLMARDGISDKSKKQRAGSERCPW 1124
              CWLS E   +++F+GPA +I+LVN+L  G+I++       G+              P 
Sbjct: 560  KVCWLSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLK-------------PE 606

Query: 1125 ASLLLPCSACGAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQ 1184
             S      +C            AR A+A L+       LL  TW+  VL +    SV+  
Sbjct: 607  VSCFENIRSC------------ARGALALLF-------LLGTTWIFGVLHVV-HASVVTA 646

Query: 1185 ALFAVFNSAQGFVITAVHCFLRREVQD 1211
             LF V N+ QG  I    C L R++Q+
Sbjct: 647  YLFTVSNAFQGMFIFLFLCVLSRKIQE 673


>gi|6912464 latrophilin 2 precursor [Homo sapiens]
          Length = 1403

 Score =  158 bits (400), Expect = 3e-38
 Identities = 163/723 (22%), Positives = 296/723 (40%), Gaps = 134/723 (18%)

Query: 544  WKKAAAGEIIYNKCPPNASGSASRRCLLSAQGVAYWGLPSFARCISHEYRYLYLSLREHL 603
            W +   G ++   CP    G+AS  C++S       G P  + C SH    L        
Sbjct: 479  WPQTQRGMMVERPCPKGTRGTASYLCMISTGTWNPKG-PDLSNCTSHWVNQL-------- 529

Query: 604  AKGQRMLAGEGMSQVVRSLQELLARRT---YYSGDLLFSVDILRNVTDTF--KRATYVPS 658
               Q++ +GE  +    SL   LA+ T    ++GD+  SV ++  + D    +     PS
Sbjct: 530  --AQKIRSGENAA----SLANELAKHTKGPVFAGDVSSSVRLMEQLVDILDAQLQELKPS 583

Query: 659  ADDV------QRFFQVVSFMVDAENKEKWD--DAQQVSPGSVHLLRVVEDFIHLVGDALK 710
              D       +     V  ++  E  E W   ++ + +  +  LL  +E+   ++ D L 
Sbjct: 584  EKDSAGRSYNKAIVDTVDNLLRPEALESWKHMNSSEQAHTATMLLDTLEEGAFVLADNLL 643

Query: 711  AFQSSLIVTDNLVISIQREPVSAVSSDITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSS 770
                  + T+N+V+ +          D  FP+ G +G    ++            LS ++
Sbjct: 644  EPTRVSMPTENIVLEVAVLSTEGQIQDFKFPL-GIKGAGSSIQ------------LSANT 690

Query: 771  PGKPATSGAAGSPGRGRGPGTVPPGPGHSHQRLLPADPDESSYFVIGAVLYRTLGLILPP 830
              + + +G A                                   +  ++YR+LG  L  
Sbjct: 691  VKQNSRNGLAK----------------------------------LVFIIYRSLGQFLST 716

Query: 831  PRPPL-------------AVTSRVMTVTVRPPTQPP--AEPLITVELSYIINGTTDPHCA 875
                +             AV S V++V++   +      +P++        +   + +C+
Sbjct: 717  ENATIKLGADFIGRNSTIAVNSHVISVSINKESSRVYLTDPVLFTLPHIDPDNYFNANCS 776

Query: 876  SWDYSRADASSGDWDTENCQTLETQAAHTRCQCQHLSTFAVLAQPP----KDLTLELAGS 931
             W+YS      G W T+ C+ ++T    T C C HL+ FA+L        KD   EL   
Sbjct: 777  FWNYSER-TMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDGVHELL-- 833

Query: 932  PSVPLVIGCAVSCMALLTLLAIYAAFWRFIKSERSIILLNFCLSILASNILILVGQSRVL 991
             +V   +G  +S + L   +  +  F+R ++S+R+ I  N C+++  +  + L+G  +  
Sbjct: 834  LTVITWVGIVISLVCLAICIFTFC-FFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKTK 892

Query: 992  SKGVCTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRMRTRLVRKRFLCL-GWGLPALVV 1050
                C + A  LHFFFL++F W+  E  Q YL ++    +   RK++  + G+  PA VV
Sbjct: 893  YAIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVV 952

Query: 1051 AVSVGFTRTKGYGTSSYCWLSLEGGLLYAFVGPAAVIVLVNMLIGIIVFNKLMARDGISD 1110
             VS      K YGT   CWL ++   +++F+GP   I+L+N++  +I   K++       
Sbjct: 953  GVSAAID-YKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNIIFLVITLCKMVKH----- 1006

Query: 1111 KSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMS 1170
                          ++ L P             S+   N  + +  +  +L LL LTW  
Sbjct: 1007 --------------SNTLKP------------DSSRLENIKSWVLGAFALLCLLGLTWSF 1040

Query: 1171 AVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREV-QDVVKC-QMGVCRADESEDS 1228
             +L + +  +++   LF +FN+ QG  I   HC L+++V ++  KC +   C      +S
Sbjct: 1041 GLLFINE-ETIVMAYLFTIFNAFQGVFIFIFHCALQKKVRKEYGKCFRHSYCCGGLPTES 1099

Query: 1229 PDS 1231
            P S
Sbjct: 1100 PHS 1102


>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
            sapiens]
          Length = 3312

 Score =  156 bits (395), Expect = 1e-37
 Identities = 179/745 (24%), Positives = 306/745 (41%), Gaps = 106/745 (14%)

Query: 506  GTQGYPCEGTGEEVKPCSEKRCPAFHEMCRDEYVMLMTWKKAAAGEIIYNKCPPNASGSA 565
            G  G  C          +   C   ++ C       + W +   G +    CP  A G+A
Sbjct: 2101 GALGRQCNSCDSPFAEVTASGCRVLYDACPKSLRSGVWWPQTKFGVLATVPCPRGALGAA 2160

Query: 566  SRRCLLSAQGVAYWGLPSFARCISHEYRYLYLSLREHLAKGQRMLAGEGMSQVVRSLQEL 625
             R C   AQG   W  P    C S  +R L L L + L   +  L      ++ + L+E+
Sbjct: 2161 VRLCD-EAQG---WLEPDLFNCTSPAFRELSLLL-DGLELNKTALDTMEAKKLAQRLREV 2215

Query: 626  LARRT-YYSGDLLFSVDILRNVT--DTFKRATYVPSADDV---QRFFQVVSFMVDAENKE 679
                  Y+S D+  +  +L ++   ++ ++   + +  D    +      S ++  E  +
Sbjct: 2216 TGHTDHYFSQDVRVTARLLAHLLAFESHQQGFGLTATQDAHFNENLLWAGSALLAPETGD 2275

Query: 680  KW----DDAQQVSPGSVHLLRVVEDFIHLVGDALKA--FQSSLIVTDNLVISIQR-EPVS 732
             W      A   SPGS  L+R +E++   +   ++        +VT N+++SI R E  S
Sbjct: 2276 LWAALGQRAPGGSPGSAGLVRHLEEYAATLARNMELTYLNPMGLVTPNIMLSIDRMEHPS 2335

Query: 733  AVSSDITFPMRGR---RGMKDWVRH------SEDRLFLPKEVLSLSSPGKPATSGAAGSP 783
            +      +P       RG   W  H      S+     P EVL  SS  + +T+ +   P
Sbjct: 2336 SPRGARRYPRYHSNLFRGQDAWDPHTHVLLPSQSPRPSPSEVLPTSSSIENSTTSSVVPP 2395

Query: 784  GRGRGPGTVPPGPGHSHQRLLPADPDESSYFVIGAVLYRTLGLILPP-----------PR 832
                 P    P PG S               +I  ++YRTLG +LP            P+
Sbjct: 2396 -----PAPPEPEPGIS---------------IIILLVYRTLGGLLPAQFQAERRGARLPQ 2435

Query: 833  PPLAVTSRVMTVTV---RPPTQPPAEPLITVELSYIINGTTDPH-CASWDYSRADASSGD 888
             P+ + S V++V V   R   +   E  I++E   +         C  WD        G 
Sbjct: 2436 NPV-MNSPVVSVAVFHGRNFLRGILESPISLEFRLLQTANRSKAICVQWDPPGLAEQHGV 2494

Query: 889  WDTENCQTLETQAAHTRCQCQHLSTFAVL--AQPPKDLTLELAGSPSVPLVIGCAVSCMA 946
            W   +C+ +    +H RC+C    TF VL  A P + L  +L        V+  AVS  A
Sbjct: 2495 WTARDCELVHRNGSHARCRCSRTGTFGVLMDASPRERLEGDLELLAVFTHVV-VAVSVAA 2553

Query: 947  LLTLLAIYAAFWRFIKSERSIILLNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFF 1006
            L+   AI  +  R +KS    I  N   ++  + +L L+G  R  ++ VCT  A  LH+F
Sbjct: 2554 LVLTAAILLSL-RSLKSNVRGIHANVAAALGVAELLFLLGIHRTHNQLVCTAVAILLHYF 2612

Query: 1007 FLSSFCWVLTEAWQSY-LAVIGRMRTRLVRKRFLCLGWGLPALVVAVSVGFTRTKGYGTS 1065
            FLS+F W+  +    Y + V  R   R   + +  LGWG+PA+++ ++VG    +GYG  
Sbjct: 2613 FLSTFAWLFVQGLHLYRMQVEPRNVDRGAMRFYHALGWGVPAVLLGLAVGLD-PEGYGNP 2671

Query: 1066 SYCWLSLEGGLLYAFVGPAAVIVLVNMLIGIIVFNKLMARDGISDKSKKQRAGSERCPWA 1125
             +CW+S+   L+++F GP  +++++N  + +     L AR   S   ++ +         
Sbjct: 2672 DFCWISVHEPLIWSFAGPVVLVIVMNGTMFL-----LAARTSCSTGQREAK--------- 2717

Query: 1126 SLLLPCSACGAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQA 1185
                                  + +  +L SS ++L L++ +W+  +LA+ +   + F  
Sbjct: 2718 ----------------------KTSALTLRSSFLLLLLVSASWLFGLLAV-NHSILAFHY 2754

Query: 1186 LFAVFNSAQGFVITAVHCFLRREVQ 1210
            L A     QG  +  + C L  + +
Sbjct: 2755 LHAGLCGLQGLAVLLLFCVLNADAR 2779


>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
          Length = 874

 Score =  155 bits (391), Expect = 4e-37
 Identities = 119/402 (29%), Positives = 182/402 (45%), Gaps = 61/402 (15%)

Query: 835  LAVTSRVMTVTVRPPT----QPPAEPLITVELSYII-----------NGTTDPHCASWDY 879
            L  TS ++++ V PP          PLITV L + +           +     +CA  D+
Sbjct: 456  LFATSHLISLEVSPPPTLSQNLSGSPLITVHLKHRLTRKQHSEATNSSNRVFVYCAFLDF 515

Query: 880  SRADASSGDWDTENCQTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGSPSVPL--- 936
            S  +   G W    C        ++ C+C HL+ FA+L Q    + LELA    V L   
Sbjct: 516  SSGE---GVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQV---VPLELARGHQVALSSI 569

Query: 937  -VIGCAVSCMALLTLLAIYAAFWRF--IKSERSIILLNFCLSILASNILILVGQSRVLSK 993
              +GC++S + L+  L  +A       I+++R  I  N   ++L + +L+L+        
Sbjct: 570  SYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEPGT 629

Query: 994  GVCTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRMRTRLVRKRFLC-LGWGLPALVVAV 1052
              C + A  LH+FFLS+F W+L E    Y  VI    +   + R+   +GWG P L+  +
Sbjct: 630  TPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGFPLLICII 689

Query: 1053 SVGFTRTKGYGTSSYCWLSLEGGLLYAFVGPAAVIVLVNMLIGIIVFNKLMARDGISDKS 1112
            S+ F     YGTS+ CWLSL  G ++AFV PA  +++VN  IGI++    +     +D  
Sbjct: 690  SLSFAMDS-YGTSNNCWLSLASGAIWAFVAPALFVIVVN--IGILIAVTRVISQISADNY 746

Query: 1113 KKQRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMSAV 1172
            K                        PS    +A A           V+LP+L  +W+  V
Sbjct: 747  K--------------------IHGDPSAFKLTAKA---------VAVLLPILGTSWVFGV 777

Query: 1173 LAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREVQDVVK 1214
            LA+ +  +V+FQ +FA  NS QG  I   HC L  EV+   K
Sbjct: 778  LAV-NGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAAFK 818


>gi|4505737 complement factor properdin precursor [Homo sapiens]
          Length = 469

 Score =  152 bits (384), Expect = 2e-36
 Identities = 94/311 (30%), Positives = 132/311 (42%), Gaps = 51/311 (16%)

Query: 315 WSPWSVCSLTCGQGLQVRTRSC--VSSPYGTLCSGPLRETRPCNNSATCPVHGVWEEWGS 372
           W PW  CS+TC +G + R R+C   +   G  C G  +E+  C+    CP HG W  WG 
Sbjct: 142 WGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGP 201

Query: 373 WSLCSRSCGRG----SRSRMRTCVPPQHG----GKACEGPELQTKLCS-MAACPVEGQWL 423
           W+ CS SC  G      +R R C  P+      GK C G   + + C+ +  CPV G W 
Sbjct: 202 WTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGGWG 261

Query: 424 EWGPWGPCSTSCANGTQQRSRKCSVAGP--AWATCTGALTDTRECSN-LECPATDSKWGP 480
            WGP  PC  +C  G     R C+   P      C G  T T  C+  + CP  D +W  
Sbjct: 262 PWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCP-VDGEWDS 320

Query: 481 WNAWSLC------SKTCD--TGWQRRFRMCQATGTQGYPCEGTGEEVKPC-SEKRCPAFH 531
           W  WS C      S +C    G Q R R C+     G+ C G  ++++ C S + CP   
Sbjct: 321 WGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRKFDGHRCAGQQQDIRHCYSIQHCP--- 377

Query: 532 EMCRDEYVMLMTWKKAAAGEIIYNKCPPNASGSASRRC------------LLSAQG---V 576
                   +  +W + +   +    C PN + +  R C            ++  QG   V
Sbjct: 378 --------LKGSWSEWSTWGLCMPPCGPNPTRARQRLCTPLLPKYPPTVSMVEGQGEKNV 429

Query: 577 AYWGLPSFARC 587
            +WG P   RC
Sbjct: 430 TFWGRP-LPRC 439



 Score =  145 bits (366), Expect = 3e-34
 Identities = 81/228 (35%), Positives = 103/228 (45%), Gaps = 22/228 (9%)

Query: 315 WSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLR------ETRPCNNSATCPVHGVWE 368
           WS W+ CS+TC +G Q+R R CV   +   CSG +       + + C +   CP  G W 
Sbjct: 83  WSTWAPCSVTCSEGSQLRYRRCVG--WNGQCSGKVAPGTLEWQLQACEDQQCCPEMGGWS 140

Query: 369 EWGSWSLCSRSCGRGSRSRMRTC-VPPQHGGKACEGPELQTKLC-SMAACPVEGQWLEWG 426
            WG W  CS +C +G+R+R R C  P    G  C G   +++ C +   CP  G W  WG
Sbjct: 141 GWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWG 200

Query: 427 PWGPCSTSCANGTQQ----RSRKCSVAGPA----WATCTGALTDTRECSNL-ECPATDSK 477
           PW PCS SC  G  +    RSRKCS   P+       C G   + R C+ L  CP     
Sbjct: 201 PWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGG- 259

Query: 478 WGPWNAWSLCSKTCDTGWQRRFRMCQATGTQ--GYPCEGTGEEVKPCS 523
           WGPW   S C  TC  G     R C     Q  G  C G       C+
Sbjct: 260 WGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICN 307



 Score =  107 bits (266), Expect = 1e-22
 Identities = 58/170 (34%), Positives = 75/170 (44%), Gaps = 13/170 (7%)

Query: 367 WEEWGSWSLCSRSCGRGSRSRMRTCVP--PQHGGKACEGP-ELQTKLCS-MAACPVEGQW 422
           W  W +W+ CS +C  GS+ R R CV    Q  GK   G  E Q + C     CP  G W
Sbjct: 80  WSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQCCPEMGGW 139

Query: 423 LEWGPWGPCSTSCANGTQQRSRKCSVAGP-AWATCTGALTDTRECSNLECPATDSKWGPW 481
             WGPW PCS +C+ GT+ R R C+   P     C G   ++  C   +   T   W  W
Sbjct: 140 SGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQVCPTHGAWATW 199

Query: 482 NAWSLCSKTCDTG----WQRRFRMCQATGTQ----GYPCEGTGEEVKPCS 523
             W+ CS +C  G     + R R C A        G PC G   E + C+
Sbjct: 200 GPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCT 249



 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 38/128 (29%), Positives = 55/128 (42%), Gaps = 16/128 (12%)

Query: 410 LCSMAACPVEGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAW-ATCTGALT------D 462
           LC     P   +W  W  W PCS +C+ G+Q R R+C      W   C+G +        
Sbjct: 71  LCQPCRSP---RWSLWSTWAPCSVTCSEGSQLRYRRC----VGWNGQCSGKVAPGTLEWQ 123

Query: 463 TRECSNLECPATDSKWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQ-GYPCEGTGEEVKP 521
            + C + +C      W  W  W  CS TC  G + R R C     + G  C G  +E + 
Sbjct: 124 LQACEDQQCCPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEA 183

Query: 522 C-SEKRCP 528
           C +++ CP
Sbjct: 184 CDTQQVCP 191


>gi|223671861 complement factor properdin precursor [Homo sapiens]
          Length = 469

 Score =  152 bits (384), Expect = 2e-36
 Identities = 94/311 (30%), Positives = 132/311 (42%), Gaps = 51/311 (16%)

Query: 315 WSPWSVCSLTCGQGLQVRTRSC--VSSPYGTLCSGPLRETRPCNNSATCPVHGVWEEWGS 372
           W PW  CS+TC +G + R R+C   +   G  C G  +E+  C+    CP HG W  WG 
Sbjct: 142 WGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGP 201

Query: 373 WSLCSRSCGRG----SRSRMRTCVPPQHG----GKACEGPELQTKLCS-MAACPVEGQWL 423
           W+ CS SC  G      +R R C  P+      GK C G   + + C+ +  CPV G W 
Sbjct: 202 WTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGGWG 261

Query: 424 EWGPWGPCSTSCANGTQQRSRKCSVAGP--AWATCTGALTDTRECSN-LECPATDSKWGP 480
            WGP  PC  +C  G     R C+   P      C G  T T  C+  + CP  D +W  
Sbjct: 262 PWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCP-VDGEWDS 320

Query: 481 WNAWSLC------SKTCD--TGWQRRFRMCQATGTQGYPCEGTGEEVKPC-SEKRCPAFH 531
           W  WS C      S +C    G Q R R C+     G+ C G  ++++ C S + CP   
Sbjct: 321 WGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRKFDGHRCAGQQQDIRHCYSIQHCP--- 377

Query: 532 EMCRDEYVMLMTWKKAAAGEIIYNKCPPNASGSASRRC------------LLSAQG---V 576
                   +  +W + +   +    C PN + +  R C            ++  QG   V
Sbjct: 378 --------LKGSWSEWSTWGLCMPPCGPNPTRARQRLCTPLLPKYPPTVSMVEGQGEKNV 429

Query: 577 AYWGLPSFARC 587
            +WG P   RC
Sbjct: 430 TFWGRP-LPRC 439



 Score =  145 bits (366), Expect = 3e-34
 Identities = 81/228 (35%), Positives = 103/228 (45%), Gaps = 22/228 (9%)

Query: 315 WSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLR------ETRPCNNSATCPVHGVWE 368
           WS W+ CS+TC +G Q+R R CV   +   CSG +       + + C +   CP  G W 
Sbjct: 83  WSTWAPCSVTCSEGSQLRYRRCVG--WNGQCSGKVAPGTLEWQLQACEDQQCCPEMGGWS 140

Query: 369 EWGSWSLCSRSCGRGSRSRMRTC-VPPQHGGKACEGPELQTKLC-SMAACPVEGQWLEWG 426
            WG W  CS +C +G+R+R R C  P    G  C G   +++ C +   CP  G W  WG
Sbjct: 141 GWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWG 200

Query: 427 PWGPCSTSCANGTQQ----RSRKCSVAGPA----WATCTGALTDTRECSNL-ECPATDSK 477
           PW PCS SC  G  +    RSRKCS   P+       C G   + R C+ L  CP     
Sbjct: 201 PWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGG- 259

Query: 478 WGPWNAWSLCSKTCDTGWQRRFRMCQATGTQ--GYPCEGTGEEVKPCS 523
           WGPW   S C  TC  G     R C     Q  G  C G       C+
Sbjct: 260 WGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICN 307



 Score =  107 bits (266), Expect = 1e-22
 Identities = 58/170 (34%), Positives = 75/170 (44%), Gaps = 13/170 (7%)

Query: 367 WEEWGSWSLCSRSCGRGSRSRMRTCVP--PQHGGKACEGP-ELQTKLCS-MAACPVEGQW 422
           W  W +W+ CS +C  GS+ R R CV    Q  GK   G  E Q + C     CP  G W
Sbjct: 80  WSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQCCPEMGGW 139

Query: 423 LEWGPWGPCSTSCANGTQQRSRKCSVAGP-AWATCTGALTDTRECSNLECPATDSKWGPW 481
             WGPW PCS +C+ GT+ R R C+   P     C G   ++  C   +   T   W  W
Sbjct: 140 SGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQVCPTHGAWATW 199

Query: 482 NAWSLCSKTCDTG----WQRRFRMCQATGTQ----GYPCEGTGEEVKPCS 523
             W+ CS +C  G     + R R C A        G PC G   E + C+
Sbjct: 200 GPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCT 249



 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 38/128 (29%), Positives = 55/128 (42%), Gaps = 16/128 (12%)

Query: 410 LCSMAACPVEGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAW-ATCTGALT------D 462
           LC     P   +W  W  W PCS +C+ G+Q R R+C      W   C+G +        
Sbjct: 71  LCQPCRSP---RWSLWSTWAPCSVTCSEGSQLRYRRC----VGWNGQCSGKVAPGTLEWQ 123

Query: 463 TRECSNLECPATDSKWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQ-GYPCEGTGEEVKP 521
            + C + +C      W  W  W  CS TC  G + R R C     + G  C G  +E + 
Sbjct: 124 LQACEDQQCCPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEA 183

Query: 522 C-SEKRCP 528
           C +++ CP
Sbjct: 184 CDTQQVCP 191


>gi|40317628 thrombospondin 2 precursor [Homo sapiens]
          Length = 1172

 Score =  145 bits (365), Expect = 4e-34
 Identities = 72/204 (35%), Positives = 101/204 (49%), Gaps = 11/204 (5%)

Query: 300 PGLYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSA 359
           P    +  G+     W+ W+ CS+TCG G Q R RSC  +     C GP  +TR C+ S 
Sbjct: 372 PSCLHSVDGEEGWSPWAEWTQCSVTCGSGTQQRGRSCDVT--SNTCLGPSIQTRACSLSK 429

Query: 360 TCPVH----GVWEEWGSWSLCSRSCGRGSRSRMRTCVPP--QHGGKACEGPELQTKLCSM 413
            C       G W  W  WS CS +CG G+ +R+R C  P  Q GGK C+G   +TK C  
Sbjct: 430 -CDTRIRQDGGWSHWSPWSSCSVTCGVGNITRIRLCNSPVPQMGGKNCKGSGRETKACQG 488

Query: 414 AACPVEGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWA--TCTGALTDTRECSNLEC 471
           A CP++G+W  W PW  C+ +CA G ++R+R C+   P +    C G + + + C+   C
Sbjct: 489 APCPIDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCNKRSC 548

Query: 472 PATDSKWGPWNAWSLCSKTCDTGW 495
           P       P    + CS   D  W
Sbjct: 549 PVDGCLSNPCFPGAQCSSFPDGSW 572



 Score =  129 bits (325), Expect = 2e-29
 Identities = 72/226 (31%), Positives = 106/226 (46%), Gaps = 17/226 (7%)

Query: 313 EEWSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSATCPVHGV--WEEW 370
           E W   S  + TC +   +  +  ++ P  T C+ P      C  S    V G   W  W
Sbjct: 331 ETWVVDSCTTCTCKKFKTICHQ--ITCPPAT-CASPSFVEGECCPSCLHSVDGEEGWSPW 387

Query: 371 GSWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMAACPV----EGQWLEWG 426
             W+ CS +CG G++ R R+C    +    C GP +QT+ CS++ C      +G W  W 
Sbjct: 388 AEWTQCSVTCGSGTQQRGRSCDVTSN---TCLGPSIQTRACSLSKCDTRIRQDGGWSHWS 444

Query: 427 PWGPCSTSCANGTQQRSRKCSVAGPAWA--TCTGALTDTRECSNLECPATDSKWGPWNAW 484
           PW  CS +C  G   R R C+   P      C G+  +T+ C    CP  D +W PW+ W
Sbjct: 445 PWSSCSVTCGVGNITRIRLCNSPVPQMGGKNCKGSGRETKACQGAPCPI-DGRWSPWSPW 503

Query: 485 SLCSKTCDTGWQRRFRMCQATGTQ--GYPCEGTGEEVKPCSEKRCP 528
           S C+ TC  G + R R+C +   Q  G  C G  +E + C+++ CP
Sbjct: 504 SACTVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCNKRSCP 549


>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
          Length = 786

 Score =  145 bits (365), Expect = 4e-34
 Identities = 104/345 (30%), Positives = 165/345 (47%), Gaps = 51/345 (14%)

Query: 874  CASWDYSRADAS-SGDWDTENCQTLETQAAHTRCQCQHLSTFAVLAQ--PPKDLTLELAG 930
            CA W   ++D+   G W TE CQ L ++   T CQC HLS+FA+L      +D  L L  
Sbjct: 446  CAFW---KSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWKLTLIT 502

Query: 931  SPSVPLVIGCAVSCMALLTLLAIYAAFWRFIKSERSIILLNFCLSILASNILILVG-QSR 989
               + L + C + C  +LT L +     R I+  R+ I L+ C+ +   + + L G ++ 
Sbjct: 503  RVGLALSLFCLLLC--ILTFLLV-----RPIQGSRTTIHLHLCICLFVGSTIFLAGIENE 555

Query: 990  VLSKGV-CTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRMRTRLVRKRFLCL-GWGLPA 1047
                G+ C + A  LH+ FL++FCW+  E  + Y  V+   + + +  R+LCL G+G+P 
Sbjct: 556  GGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPL 615

Query: 1048 LVVAVSVGFTRTKGYGTSSYCWLSLEGGLLYAFVGPAAVIVLVNMLIGIIVFNKLMAR-D 1106
            L+V VS     +KGYG   YCWL  E G L++F+GP   I+L N +I +    KL  +  
Sbjct: 616  LIVGVSAAIY-SKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFS 674

Query: 1107 GISDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMASLWSSCVVLPLLAL 1166
             I+   KK                                 + A A   ++   L LL  
Sbjct: 675  EINPDMKK--------------------------------LKKARALTITAIAQLFLLGC 702

Query: 1167 TWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREVQD 1211
            TW+   L + D RS++   +F + N  QG  +  +HC L ++V++
Sbjct: 703  TWVFG-LFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVRE 746


>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
          Length = 742

 Score =  145 bits (365), Expect = 4e-34
 Identities = 104/345 (30%), Positives = 165/345 (47%), Gaps = 51/345 (14%)

Query: 874  CASWDYSRADAS-SGDWDTENCQTLETQAAHTRCQCQHLSTFAVLAQ--PPKDLTLELAG 930
            CA W   ++D+   G W TE CQ L ++   T CQC HLS+FA+L      +D  L L  
Sbjct: 402  CAFW---KSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWKLTLIT 458

Query: 931  SPSVPLVIGCAVSCMALLTLLAIYAAFWRFIKSERSIILLNFCLSILASNILILVG-QSR 989
               + L + C + C  +LT L +     R I+  R+ I L+ C+ +   + + L G ++ 
Sbjct: 459  RVGLALSLFCLLLC--ILTFLLV-----RPIQGSRTTIHLHLCICLFVGSTIFLAGIENE 511

Query: 990  VLSKGV-CTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRMRTRLVRKRFLCL-GWGLPA 1047
                G+ C + A  LH+ FL++FCW+  E  + Y  V+   + + +  R+LCL G+G+P 
Sbjct: 512  GGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPL 571

Query: 1048 LVVAVSVGFTRTKGYGTSSYCWLSLEGGLLYAFVGPAAVIVLVNMLIGIIVFNKLMAR-D 1106
            L+V VS     +KGYG   YCWL  E G L++F+GP   I+L N +I +    KL  +  
Sbjct: 572  LIVGVSAAIY-SKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFS 630

Query: 1107 GISDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMASLWSSCVVLPLLAL 1166
             I+   KK                                 + A A   ++   L LL  
Sbjct: 631  EINPDMKK--------------------------------LKKARALTITAIAQLFLLGC 658

Query: 1167 TWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREVQD 1211
            TW+   L + D RS++   +F + N  QG  +  +HC L ++V++
Sbjct: 659  TWVFG-LFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVRE 702


>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
          Length = 835

 Score =  145 bits (365), Expect = 4e-34
 Identities = 104/345 (30%), Positives = 165/345 (47%), Gaps = 51/345 (14%)

Query: 874  CASWDYSRADAS-SGDWDTENCQTLETQAAHTRCQCQHLSTFAVLAQ--PPKDLTLELAG 930
            CA W   ++D+   G W TE CQ L ++   T CQC HLS+FA+L      +D  L L  
Sbjct: 495  CAFW---KSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWKLTLIT 551

Query: 931  SPSVPLVIGCAVSCMALLTLLAIYAAFWRFIKSERSIILLNFCLSILASNILILVG-QSR 989
               + L + C + C  +LT L +     R I+  R+ I L+ C+ +   + + L G ++ 
Sbjct: 552  RVGLALSLFCLLLC--ILTFLLV-----RPIQGSRTTIHLHLCICLFVGSTIFLAGIENE 604

Query: 990  VLSKGV-CTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRMRTRLVRKRFLCL-GWGLPA 1047
                G+ C + A  LH+ FL++FCW+  E  + Y  V+   + + +  R+LCL G+G+P 
Sbjct: 605  GGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPL 664

Query: 1048 LVVAVSVGFTRTKGYGTSSYCWLSLEGGLLYAFVGPAAVIVLVNMLIGIIVFNKLMAR-D 1106
            L+V VS     +KGYG   YCWL  E G L++F+GP   I+L N +I +    KL  +  
Sbjct: 665  LIVGVSAAIY-SKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFS 723

Query: 1107 GISDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMASLWSSCVVLPLLAL 1166
             I+   KK                                 + A A   ++   L LL  
Sbjct: 724  EINPDMKK--------------------------------LKKARALTITAIAQLFLLGC 751

Query: 1167 TWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREVQD 1211
            TW+   L + D RS++   +F + N  QG  +  +HC L ++V++
Sbjct: 752  TWVFG-LFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVRE 795


>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
          Length = 1151

 Score =  143 bits (360), Expect = 2e-33
 Identities = 88/261 (33%), Positives = 118/261 (45%), Gaps = 38/261 (14%)

Query: 300 PGLYMAQTGDPAA-EEWSPWSVCSLTCGQGLQVRTRSCVSSPY----GTLCSGPLRETRP 354
           P +++A      A   WS W++CS +CG G QVR RSC S+P     G +C G  RE R 
Sbjct: 654 PAIHIANCSRNGAWTPWSSWALCSTSCGIGFQVRQRSC-SNPAPRHGGRICVGKSREERF 712

Query: 355 CNNSATCPVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMA 414
           CN +  CPV   W  WGSWS CS +CG G +SR R C      G +C G  ++ K C+  
Sbjct: 713 CNENTPCPVPIFWASWGSWSKCSSNCGGGMQSRRRAC----ENGNSCLGCGVEFKTCNPE 768

Query: 415 ACPVEGQWLEWGPWGPCSTSCANGTQQRSR-----KCSVAGPAWATCTGALTDTREC--- 466
            CP   +   W PW P + +   G +Q  R     +  +A P         T+TR C   
Sbjct: 769 GCPEVRRNTPWTPWLPVNVT-QGGARQEQRFRFTCRAPLADPHGLQFGRRRTETRTCPAD 827

Query: 467 ----------------SNLECPATDS-KWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQ- 508
                           S    P T S  W  W  WS CS+ C+ G++ R R C     + 
Sbjct: 828 GSGSCDTDALVEVLLRSGSTSPHTVSGGWAAWGPWSSCSRDCELGFRVRKRTCTNPEPRN 887

Query: 509 -GYPCEGTGEEVKPCSEKRCP 528
            G PC G   E + C+ + CP
Sbjct: 888 GGLPCVGDAAEYQDCNPQACP 908



 Score =  139 bits (349), Expect = 3e-32
 Identities = 80/243 (32%), Positives = 104/243 (42%), Gaps = 35/243 (14%)

Query: 315  WSPWSVCSLTCG-----QGLQVRTRSCVSSPYGTLCSGPLRETRPC--NNSATCP----- 362
            W+PW   ++T G     Q  +   R+ ++ P+G        ETR C  + S +C      
Sbjct: 779  WTPWLPVNVTQGGARQEQRFRFTCRAPLADPHGLQFGRRRTETRTCPADGSGSCDTDALV 838

Query: 363  -------------VHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQ--HGGKACEGPELQ 407
                         V G W  WG WS CSR C  G R R RTC  P+  +GG  C G   +
Sbjct: 839  EVLLRSGSTSPHTVSGGWAAWGPWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAE 898

Query: 408  TKLCSMAACPVEGQWLEWGPWGPCSTSCANGTQQRSRKCS--VAGPAWATCTGALTDTRE 465
             + C+  ACPV G W  W  W PCS SC  G  QR+R C+     P    C G  T+   
Sbjct: 899  YQDCNPQACPVRGAWSCWTSWSPCSASCGGGHYQRTRSCTSPAPSPGEDICLGLHTEEAL 958

Query: 466  CSNLECPATDSKWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQGYPCEGTGEEVKPCSEK 525
            C+   CP     W PW+ WS C+   D G Q R R C+        C G   + +PC   
Sbjct: 959  CATQACP---EGWSPWSEWSKCT---DDGAQSRSRHCEELLPGSSACAGNSSQSRPCPYS 1012

Query: 526  RCP 528
              P
Sbjct: 1013 EIP 1015



 Score =  113 bits (283), Expect = 1e-24
 Identities = 64/183 (34%), Positives = 82/183 (44%), Gaps = 15/183 (8%)

Query: 307 TGDPAAEEWSPWSVCSLTCGQ---GLQVRTRSCVSSPYGTLCSGPLRETRPCNNSATCPV 363
           T D     WSPW  C    G        R RSC S      C G L    P  + A C  
Sbjct: 607 TRDGGFGPWSPWQPCEHLDGDNSGSCLCRARSCDSP--RPRCGG-LDCLGPAIHIANCSR 663

Query: 364 HGVWEEWGSWSLCSRSCGRGSRSRMRTC--VPPQHGGKACEGPELQTKLCS-MAACPVEG 420
           +G W  W SW+LCS SCG G + R R+C    P+HGG+ C G   + + C+    CPV  
Sbjct: 664 NGAWTPWSSWALCSTSCGIGFQVRQRSCSNPAPRHGGRICVGKSREERFCNENTPCPVPI 723

Query: 421 QWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPAT--DSKW 478
            W  WG W  CS++C  G Q R R C        +C G   + + C+   CP    ++ W
Sbjct: 724 FWASWGSWSKCSSNCGGGMQSRRRACENGN----SCLGCGVEFKTCNPEGCPEVRRNTPW 779

Query: 479 GPW 481
            PW
Sbjct: 780 TPW 782



 Score =  105 bits (263), Expect = 3e-22
 Identities = 66/185 (35%), Positives = 77/185 (41%), Gaps = 23/185 (12%)

Query: 357 NSATCPVHGVWEE-----WGSWSLCSRSCGRGSRS---RMRTCVPPQH--GGKACEGPEL 406
           N   CPV  V  +     W  W  C    G  S S   R R+C  P+   GG  C GP +
Sbjct: 597 NITACPVRNVTRDGGFGPWSPWQPCEHLDGDNSGSCLCRARSCDSPRPRCGGLDCLGPAI 656

Query: 407 QTKLCSMAACPVEGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGP--AWATCTGALTDTR 464
                 +A C   G W  W  W  CSTSC  G Q R R CS   P      C G   + R
Sbjct: 657 H-----IANCSRNGAWTPWSSWALCSTSCGIGFQVRQRSCSNPAPRHGGRICVGKSREER 711

Query: 465 ECS-NLECPATDSKWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQGYPCEGTGEEVKPCS 523
            C+ N  CP     W  W +WS CS  C  G Q R R C+     G  C G G E K C+
Sbjct: 712 FCNENTPCP-VPIFWASWGSWSKCSSNCGGGMQSRRRACE----NGNSCLGCGVEFKTCN 766

Query: 524 EKRCP 528
            + CP
Sbjct: 767 PEGCP 771



 Score = 70.9 bits (172), Expect = 9e-12
 Identities = 66/215 (30%), Positives = 84/215 (39%), Gaps = 41/215 (19%)

Query: 224  SCPGEAGAGSTTTTS-------PGPPAAHTLSNALVPGGPAPPAEADLHSGSSNDLFTTE 276
            +CP + G+GS  T +        G  + HT+S      GP      D   G     F   
Sbjct: 823  TCPAD-GSGSCDTDALVEVLLRSGSTSPHTVSGGWAAWGPWSSCSRDCELG-----FRVR 876

Query: 277  MRYGEEPEEEPKVKTQWPRSADEPGLYMA---QTGDPAA-------EEWSPWSVCSLTCG 326
             R    PE         PR+   P +  A   Q  +P A         W+ WS CS +CG
Sbjct: 877  KRTCTNPE---------PRNGGLPCVGDAAEYQDCNPQACPVRGAWSCWTSWSPCSASCG 927

Query: 327  QGLQVRTRSCVS---SPYGTLCSGPLRETRPCNNSATCPVHGVWEEWGSWSLCSRSCGRG 383
             G   RTRSC S   SP   +C G   E   C   A CP     E W  WS  S+    G
Sbjct: 928  GGHYQRTRSCTSPAPSPGEDICLGLHTEEALCATQA-CP-----EGWSPWSEWSKCTDDG 981

Query: 384  SRSRMRTCVPPQHGGKACEGPELQTKLCSMAACPV 418
            ++SR R C     G  AC G   Q++ C  +  PV
Sbjct: 982  AQSRSRHCEELLPGSSACAGNSSQSRPCPYSEIPV 1016


>gi|40317626 thrombospondin 1 precursor [Homo sapiens]
          Length = 1170

 Score =  142 bits (359), Expect = 2e-33
 Identities = 73/204 (35%), Positives = 97/204 (47%), Gaps = 9/204 (4%)

Query: 300 PGLYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSA 359
           P  + + + D     WS W+ CS +CG G+Q R RSC S      C G   +TR C+   
Sbjct: 370 PRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDS--LNNRCEGSSVQTRTCHIQE 427

Query: 360 T---CPVHGVWEEWGSWSLCSRSCGRGSRSRMRTC--VPPQHGGKACEGPELQTKLCSMA 414
                   G W  W  WS CS +CG G  +R+R C    PQ  GK CEG   +TK C   
Sbjct: 428 CDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKD 487

Query: 415 ACPVEGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWA--TCTGALTDTRECSNLECP 472
           ACP+ G W  W PW  CS +C  G Q+RSR C+   P +    C G +T+ + C+  +CP
Sbjct: 488 ACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCP 547

Query: 473 ATDSKWGPWNAWSLCSKTCDTGWQ 496
                  P  A   C+   D  W+
Sbjct: 548 IDGCLSNPCFAGVKCTSYPDGSWK 571



 Score =  126 bits (317), Expect = 1e-28
 Identities = 67/206 (32%), Positives = 90/206 (43%), Gaps = 24/206 (11%)

Query: 343 TLCSGPLRETRPCNNSAT-----CP-------VHGVWEEWGSWSLCSRSCGRGSRSRMRT 390
           T+C        PC+N+       CP           W  W  W+ CS SCG G + R R+
Sbjct: 346 TICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRS 405

Query: 391 CVPPQHGGKACEGPELQTKLCSMAACPV----EGQWLEWGPWGPCSTSCANGTQQRSRKC 446
           C         CEG  +QT+ C +  C      +G W  W PW  CS +C +G   R R C
Sbjct: 406 C---DSLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLC 462

Query: 447 SVAGPAW--ATCTGALTDTRECSNLECPATDSKWGPWNAWSLCSKTCDTGWQRRFRMCQA 504
           +   P      C G   +T+ C    CP     WGPW+ W +CS TC  G Q+R R+C  
Sbjct: 463 NSPSPQMNGKPCEGEARETKACKKDACPINGG-WGPWSPWDICSVTCGGGVQKRSRLCNN 521

Query: 505 TGTQ--GYPCEGTGEEVKPCSEKRCP 528
              Q  G  C G   E + C+++ CP
Sbjct: 522 PTPQFGGKDCVGDVTENQICNKQDCP 547


>gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
          Length = 3080

 Score =  141 bits (355), Expect = 6e-33
 Identities = 104/373 (27%), Positives = 167/373 (44%), Gaps = 49/373 (13%)

Query: 873  HCASWDYSRADASSGDWDTENCQTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGSP 932
            HCA WD+   +   G W++  C+  ET   +T CQC HL+ F VL    +  T++     
Sbjct: 2684 HCAFWDFENNNGLGG-WNSSGCKVKETNVNYTICQCDHLTHFGVLMDLSRS-TVDSVNEQ 2741

Query: 933  SVPLV--IGCAVSCMALLTLLAIYAAFWRFIKSERSIILLNFCLSILASNILILVGQ--S 988
             + L+   GC +S + L   +  Y AF +  K   + IL+N C ++L  N++ L+    S
Sbjct: 2742 ILALITYTGCGISSIFLGVAVVTYIAFHKLRKDYPAKILINLCTALLMLNLVFLINSWLS 2801

Query: 989  RVLSKGVCTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRMRTRLVR--KRFLCLGWGLP 1046
                 GVC   A  LH+F L SF W+  EA   YLA++      +     +F  +GWG+P
Sbjct: 2802 SFQKVGVCITAAVALHYFLLVSFTWMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIP 2861

Query: 1047 ALVVAVSVGFTRTKGYGTSS----YCWLSLEGGLLYAFVGPAAVIVLVNMLIGIIVFNKL 1102
            A++VA++V   +   YGT S    +CW+  +     + V    +I L+N+ +   V   L
Sbjct: 2862 AIMVAITVSVKKDL-YGTLSPTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMFCTV---L 2917

Query: 1103 MARDGISDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMASLWSSCVVLP 1162
            +  + +  + +K R                               +  +  L  +  +  
Sbjct: 2918 VQLNSVKSQIQKTR------------------------------RKMILHDLKGTMSLTF 2947

Query: 1163 LLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREVQDVVKCQM--GVC 1220
            LL LTW  A  A    R+  F  LFA+FN+ QGF I   HC ++  V++  +  +  G  
Sbjct: 2948 LLGLTWGFAFFAWGPMRN-FFLYLFAIFNTLQGFFIFVFHCVMKESVREQWQIHLCCGWL 3006

Query: 1221 RADESEDSPDSCK 1233
            R D S D    C+
Sbjct: 3007 RLDNSSDGSSRCQ 3019


>gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo sapiens]
          Length = 1079

 Score =  138 bits (348), Expect = 4e-32
 Identities = 184/734 (25%), Positives = 281/734 (38%), Gaps = 127/734 (17%)

Query: 537  EYVMLMTWKKAAAGEIIYNKCPPNASGSASRRCLLSAQGVAYWGLPSFARCISHEYRYLY 596
            E   ++TW    AG +    CP +  G   R C   A GV  WG P  + C   + R L 
Sbjct: 433  EDASVLTWNVTKAGHVAQAPCPESKRGIVRRLC--GADGV--WG-PVHSSCT--DARLLA 485

Query: 597  LSLREHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDLLFSVDILRNVTDTFKRATYV 656
            L  R  L +  +    E + Q++  L    A  +  S DLL  +  ++ V      A   
Sbjct: 486  LFTRTKLLQAGQGSPAEEVPQILAQLPGQAAEASSPS-DLLTLLSTMKYVAKVVAEARIQ 544

Query: 657  PSADDVQRFFQVVSFMVDAENKEKWDDAQQVSP--GSVHLLRVVEDFIHLVGDALKAFQS 714
                 ++        ++D + +  W  AQ   P  GS  LL  VE     +      F  
Sbjct: 545  LDRRALKNLLIATDKVLDMDTRSLWTLAQARKPWAGST-LLLAVETLACSLCPQDHPFAF 603

Query: 715  SLIVTDNLVISIQR-EPVSAVSSDITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSSPGK 773
            SL    N+++  Q   P       I+FP R         RHS   L      +S++S   
Sbjct: 604  SL---PNVLLQSQLFGPTFPADYSISFPTRPPL-QAQIPRHSLAPLVRNGTEISITSLVL 659

Query: 774  PATSGAAGSPGRGRGPGTVPPGPGHSHQRLLPADPDESSYFVIGAVLYRTLGLILPPPRP 833
                                         LLP++  +     +G  LY T GL+L     
Sbjct: 660  ------------------------RKLDHLLPSNYGQG----LGDSLYATPGLVL----- 686

Query: 834  PLAVTSRVMTVTVRPPTQPPAEPLITVELSYIINGTTD--PHCASWDYSRADASSGDWDT 891
                   V+++          E ++         G TD  PHC  WD+S      G W  
Sbjct: 687  -------VISIMAGDRAFSQGEVIMDF-------GNTDGSPHCVFWDHSLFQGRGG-WSK 731

Query: 892  ENCQTLETQAAHT-RCQCQHLSTFAVLAQP---PKDLTLELAGSPSVPLVIGCAVSCMAL 947
            E CQ     A+ T +C CQHL+ F+VL  P   P++  L L         +G   S +AL
Sbjct: 732  EGCQAQVASASPTAQCLCQHLTAFSVLMSPHTVPEEPALALLTQ------VGLGASILAL 785

Query: 948  LTLLAIYAAFWRFIKSE-----RSIILLNFCLSILASNILILVGQSRVLSKG----VCTM 998
            L  L +Y   WR +        R   LLN    +LA++   L   +  LS G    +C  
Sbjct: 786  LVCLGVYWLVWRVVVRNKISYFRHAALLNMVFCLLAADTCFL--GAPFLSPGPRSPLCLA 843

Query: 999  TAAFLHFFFLSSFCWVLTEAW---QSYLAVIGRMRTRLVRKRFLCLGWGLPALVVAVSVG 1055
             A   HF +L++F W+L +A       L V  ++    V    + LG+  P  +  V++G
Sbjct: 844  AAFLCHFLYLATFFWMLAQALVLAHQLLFVFHQLAKHRVLPLMVLLGYLCPLGLAGVTLG 903

Query: 1056 FTRTKG-YGTSSYCWLSLEGGLLYAFVGPAAVIVLVNMLIGIIVFNKLMARDGISDKSKK 1114
                +G Y     CWL  +GG LY FVGP   I+ VN L+  +   KL+ R  +S+    
Sbjct: 904  LYLPQGQYLREGECWLDGKGGALYTFVGPVLAIIGVNGLVLAMAMLKLL-RPSLSEG--- 959

Query: 1115 QRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMASLWSSCVVL-PLLALTWMSAVL 1173
                                          A  R A+  +  + ++L P+  LTW   + 
Sbjct: 960  ----------------------------PPAEKRQALLGVIKALLILTPIFGLTWGLGLA 991

Query: 1174 AMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREVQDVVKCQMGVCRADESEDSPDSCK 1233
             + +  S +   +F + N+ QG  I    C + R++Q+ ++ +    +A  S  S  SC 
Sbjct: 992  TLLEEVSTVPHYIFTILNTLQGVFILLFGCLMDRKIQEALRKRFCRAQAPSSTISLVSC- 1050

Query: 1234 NGQLQILSDFEKDV 1247
               LQILS   K +
Sbjct: 1051 --CLQILSCASKSM 1062


>gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]
          Length = 995

 Score =  136 bits (343), Expect = 1e-31
 Identities = 122/438 (27%), Positives = 190/438 (43%), Gaps = 61/438 (13%)

Query: 821  YRTLGLILPPPRPPLAVTSRVMTVTVRPPTQPPAEPLITVELSYIINGTTDP---HCASW 877
            + T  L   P    L++ S V++ +V   T       +TV L +I N + D     C  W
Sbjct: 493  FETPALFQDPSLENLSLISYVISSSVANLTVRNLTRNVTVTLKHI-NPSQDELTVRCVFW 551

Query: 878  DYSRADASSGDWDTENCQTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGSPSVPLV 937
            D  R +   G W    C   + +   T C C HL++F VL    +   L  A   ++  +
Sbjct: 552  DLGR-NGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLP-AQMMALTFI 609

Query: 938  --IGCAVSCMALLTLLAIYAAFWRFIKSERSIILLNFCLSILASNILILVGQSRVLSK-- 993
              IGC +S + L   L  Y AF +  +   S IL+  C ++L  N++ L+     L K  
Sbjct: 610  TYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQ 669

Query: 994  GVCTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRMRTRLVRK---RFLCLGWGLPALVV 1050
            G+C   A FLH+F L SF W+  EA+  YLA++    T  +RK   +F  +GWG+PA+VV
Sbjct: 670  GLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNT-YIRKYILKFCIVGWGVPAVVV 728

Query: 1051 AVSVGFTRTKGYGTSSY-----------CWLSLEGGLLYAFVGPAAVIVLVNMLIGIIVF 1099
             + +  +    YG  SY           CW++         VG   VI L+N+ + I+V 
Sbjct: 729  TIILTIS-PDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVL 787

Query: 1100 NKLMARDGISDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMASLWSSCV 1159
             +L          KK++ G++R                          + ++  L S   
Sbjct: 788  VQLCR------IKKKKQLGAQR--------------------------KTSIQDLRSIAG 815

Query: 1160 VLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREVQDVVKCQM-- 1217
            +  LL +TW  A  A     +V F  LFA+FN+ QGF I   +C  +  V+   +  +  
Sbjct: 816  LTFLLGITWGFAFFAW-GPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWRRYLCC 874

Query: 1218 GVCRADESEDSPDSCKNG 1235
            G  R  E+ D   +  NG
Sbjct: 875  GKLRLAENSDWSKTATNG 892


>gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]
          Length = 1003

 Score =  136 bits (343), Expect = 1e-31
 Identities = 122/438 (27%), Positives = 190/438 (43%), Gaps = 61/438 (13%)

Query: 821  YRTLGLILPPPRPPLAVTSRVMTVTVRPPTQPPAEPLITVELSYIINGTTDP---HCASW 877
            + T  L   P    L++ S V++ +V   T       +TV L +I N + D     C  W
Sbjct: 501  FETPALFQDPSLENLSLISYVISSSVANLTVRNLTRNVTVTLKHI-NPSQDELTVRCVFW 559

Query: 878  DYSRADASSGDWDTENCQTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGSPSVPLV 937
            D  R +   G W    C   + +   T C C HL++F VL    +   L  A   ++  +
Sbjct: 560  DLGR-NGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLP-AQMMALTFI 617

Query: 938  --IGCAVSCMALLTLLAIYAAFWRFIKSERSIILLNFCLSILASNILILVGQSRVLSK-- 993
              IGC +S + L   L  Y AF +  +   S IL+  C ++L  N++ L+     L K  
Sbjct: 618  TYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQ 677

Query: 994  GVCTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRMRTRLVRK---RFLCLGWGLPALVV 1050
            G+C   A FLH+F L SF W+  EA+  YLA++    T  +RK   +F  +GWG+PA+VV
Sbjct: 678  GLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNT-YIRKYILKFCIVGWGVPAVVV 736

Query: 1051 AVSVGFTRTKGYGTSSY-----------CWLSLEGGLLYAFVGPAAVIVLVNMLIGIIVF 1099
             + +  +    YG  SY           CW++         VG   VI L+N+ + I+V 
Sbjct: 737  TIILTIS-PDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVL 795

Query: 1100 NKLMARDGISDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMASLWSSCV 1159
             +L          KK++ G++R                          + ++  L S   
Sbjct: 796  VQLCR------IKKKKQLGAQR--------------------------KTSIQDLRSIAG 823

Query: 1160 VLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREVQDVVKCQM-- 1217
            +  LL +TW  A  A     +V F  LFA+FN+ QGF I   +C  +  V+   +  +  
Sbjct: 824  LTFLLGITWGFAFFAW-GPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWRRYLCC 882

Query: 1218 GVCRADESEDSPDSCKNG 1235
            G  R  E+ D   +  NG
Sbjct: 883  GKLRLAENSDWSKTATNG 900


>gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]
          Length = 1017

 Score =  136 bits (343), Expect = 1e-31
 Identities = 122/438 (27%), Positives = 190/438 (43%), Gaps = 61/438 (13%)

Query: 821  YRTLGLILPPPRPPLAVTSRVMTVTVRPPTQPPAEPLITVELSYIINGTTDP---HCASW 877
            + T  L   P    L++ S V++ +V   T       +TV L +I N + D     C  W
Sbjct: 515  FETPALFQDPSLENLSLISYVISSSVANLTVRNLTRNVTVTLKHI-NPSQDELTVRCVFW 573

Query: 878  DYSRADASSGDWDTENCQTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGSPSVPLV 937
            D  R +   G W    C   + +   T C C HL++F VL    +   L  A   ++  +
Sbjct: 574  DLGR-NGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLP-AQMMALTFI 631

Query: 938  --IGCAVSCMALLTLLAIYAAFWRFIKSERSIILLNFCLSILASNILILVGQSRVLSK-- 993
              IGC +S + L   L  Y AF +  +   S IL+  C ++L  N++ L+     L K  
Sbjct: 632  TYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQ 691

Query: 994  GVCTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRMRTRLVRK---RFLCLGWGLPALVV 1050
            G+C   A FLH+F L SF W+  EA+  YLA++    T  +RK   +F  +GWG+PA+VV
Sbjct: 692  GLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNT-YIRKYILKFCIVGWGVPAVVV 750

Query: 1051 AVSVGFTRTKGYGTSSY-----------CWLSLEGGLLYAFVGPAAVIVLVNMLIGIIVF 1099
             + +  +    YG  SY           CW++         VG   VI L+N+ + I+V 
Sbjct: 751  TIILTIS-PDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVL 809

Query: 1100 NKLMARDGISDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMASLWSSCV 1159
             +L          KK++ G++R                          + ++  L S   
Sbjct: 810  VQLCR------IKKKKQLGAQR--------------------------KTSIQDLRSIAG 837

Query: 1160 VLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREVQDVVKCQM-- 1217
            +  LL +TW  A  A     +V F  LFA+FN+ QGF I   +C  +  V+   +  +  
Sbjct: 838  LTFLLGITWGFAFFAW-GPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWRRYLCC 896

Query: 1218 GVCRADESEDSPDSCKNG 1235
            G  R  E+ D   +  NG
Sbjct: 897  GKLRLAENSDWSKTATNG 914


>gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]
          Length = 1014

 Score =  136 bits (343), Expect = 1e-31
 Identities = 122/438 (27%), Positives = 190/438 (43%), Gaps = 61/438 (13%)

Query: 821  YRTLGLILPPPRPPLAVTSRVMTVTVRPPTQPPAEPLITVELSYIINGTTDP---HCASW 877
            + T  L   P    L++ S V++ +V   T       +TV L +I N + D     C  W
Sbjct: 512  FETPALFQDPSLENLSLISYVISSSVANLTVRNLTRNVTVTLKHI-NPSQDELTVRCVFW 570

Query: 878  DYSRADASSGDWDTENCQTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGSPSVPLV 937
            D  R +   G W    C   + +   T C C HL++F VL    +   L  A   ++  +
Sbjct: 571  DLGR-NGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLP-AQMMALTFI 628

Query: 938  --IGCAVSCMALLTLLAIYAAFWRFIKSERSIILLNFCLSILASNILILVGQSRVLSK-- 993
              IGC +S + L   L  Y AF +  +   S IL+  C ++L  N++ L+     L K  
Sbjct: 629  TYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQ 688

Query: 994  GVCTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRMRTRLVRK---RFLCLGWGLPALVV 1050
            G+C   A FLH+F L SF W+  EA+  YLA++    T  +RK   +F  +GWG+PA+VV
Sbjct: 689  GLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNT-YIRKYILKFCIVGWGVPAVVV 747

Query: 1051 AVSVGFTRTKGYGTSSY-----------CWLSLEGGLLYAFVGPAAVIVLVNMLIGIIVF 1099
             + +  +    YG  SY           CW++         VG   VI L+N+ + I+V 
Sbjct: 748  TIILTIS-PDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVL 806

Query: 1100 NKLMARDGISDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMASLWSSCV 1159
             +L          KK++ G++R                          + ++  L S   
Sbjct: 807  VQLCR------IKKKKQLGAQR--------------------------KTSIQDLRSIAG 834

Query: 1160 VLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREVQDVVKCQM-- 1217
            +  LL +TW  A  A     +V F  LFA+FN+ QGF I   +C  +  V+   +  +  
Sbjct: 835  LTFLLGITWGFAFFAW-GPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWRRYLCC 893

Query: 1218 GVCRADESEDSPDSCKNG 1235
            G  R  E+ D   +  NG
Sbjct: 894  GKLRLAENSDWSKTATNG 911


>gi|148719671 G-protein coupled receptor 116 [Homo sapiens]
          Length = 1346

 Score =  136 bits (342), Expect = 2e-31
 Identities = 107/399 (26%), Positives = 175/399 (43%), Gaps = 50/399 (12%)

Query: 839  SRVMTVTVRPPTQPPAEPLITVELSYIINGTTDPHCASWDYSRADASSGDWDTENCQTLE 898
            S VMT TV   T  P    +T + +    G T   C  W++  A+ ++G WD+  C   E
Sbjct: 921  SLVMTTTVSHNTTMPFRISMTFKNNSPSGGETK--CVFWNFRLAN-NTGGWDSSGCYVEE 977

Query: 899  TQAAHTRCQCQHLSTFAVLAQPPKDLTLELAG-SPSVPLVIGCAVSCMALLTLLAIYAAF 957
                +  C C HL++F++L  P       L G    +   +G   S ++L   L + A  
Sbjct: 978  GDGDNVTCICDHLTSFSILMSPDSPDPSSLLGILLDIISYVGVGFSILSLAACLVVEAVV 1037

Query: 958  WRFIKSERSIILLNFCLSILASNILI----------LVGQSRVLSKGVCTMTAAFLHFFF 1007
            W+ +   R+  + + C+  +A+++L+          +     +L K  C     F+HFF+
Sbjct: 1038 WKSVTKNRTSYMRHTCIVNIAASLLVANTWFIVVAAIQDNRYILCKTACVAATFFIHFFY 1097

Query: 1008 LSSFCWVLTEAWQSY--LAVIGRMRTRLVRKRF-LCLGWGLPALVVAVSVGFTRTKG-YG 1063
            LS F W+LT     +  L  I    +R  +K    CLG+G P  +  +++G T+ +  Y 
Sbjct: 1098 LSVFFWMLTLGLMLFYRLVFILHETSRSTQKAIAFCLGYGCPLAISVITLGATQPREVYT 1157

Query: 1064 TSSYCWLSLEG-GLLYAFVGPAAVIVLVNMLIGIIVFNKLMARDGISDKSKKQRAGSERC 1122
              + CWL+ E    L AF  PA +IV+VN+ I I+V  K++ R  I DK  KQ       
Sbjct: 1158 RKNVCWLNWEDTKALLAFAIPALIIVVVNITITIVVITKIL-RPSIGDKPCKQEK----- 1211

Query: 1123 PWASLLLPCSACGAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVL 1182
              +SL     + G                       V+ PLL LTW   +  +    +++
Sbjct: 1212 --SSLFQISKSIG-----------------------VLTPLLGLTWGFGLTTVFPGTNLV 1246

Query: 1183 FQALFAVFNSAQGFVITAVHCFLRREVQDVVKCQMGVCR 1221
            F  +FA+ N  QG  I    C    +VQ+ +  +  + R
Sbjct: 1247 FHIIFAILNVFQGLFILLFGCLWDLKVQEALLNKFSLSR 1285


>gi|148719673 G-protein coupled receptor 116 [Homo sapiens]
          Length = 1346

 Score =  136 bits (342), Expect = 2e-31
 Identities = 107/399 (26%), Positives = 175/399 (43%), Gaps = 50/399 (12%)

Query: 839  SRVMTVTVRPPTQPPAEPLITVELSYIINGTTDPHCASWDYSRADASSGDWDTENCQTLE 898
            S VMT TV   T  P    +T + +    G T   C  W++  A+ ++G WD+  C   E
Sbjct: 921  SLVMTTTVSHNTTMPFRISMTFKNNSPSGGETK--CVFWNFRLAN-NTGGWDSSGCYVEE 977

Query: 899  TQAAHTRCQCQHLSTFAVLAQPPKDLTLELAG-SPSVPLVIGCAVSCMALLTLLAIYAAF 957
                +  C C HL++F++L  P       L G    +   +G   S ++L   L + A  
Sbjct: 978  GDGDNVTCICDHLTSFSILMSPDSPDPSSLLGILLDIISYVGVGFSILSLAACLVVEAVV 1037

Query: 958  WRFIKSERSIILLNFCLSILASNILI----------LVGQSRVLSKGVCTMTAAFLHFFF 1007
            W+ +   R+  + + C+  +A+++L+          +     +L K  C     F+HFF+
Sbjct: 1038 WKSVTKNRTSYMRHTCIVNIAASLLVANTWFIVVAAIQDNRYILCKTACVAATFFIHFFY 1097

Query: 1008 LSSFCWVLTEAWQSY--LAVIGRMRTRLVRKRF-LCLGWGLPALVVAVSVGFTRTKG-YG 1063
            LS F W+LT     +  L  I    +R  +K    CLG+G P  +  +++G T+ +  Y 
Sbjct: 1098 LSVFFWMLTLGLMLFYRLVFILHETSRSTQKAIAFCLGYGCPLAISVITLGATQPREVYT 1157

Query: 1064 TSSYCWLSLEG-GLLYAFVGPAAVIVLVNMLIGIIVFNKLMARDGISDKSKKQRAGSERC 1122
              + CWL+ E    L AF  PA +IV+VN+ I I+V  K++ R  I DK  KQ       
Sbjct: 1158 RKNVCWLNWEDTKALLAFAIPALIIVVVNITITIVVITKIL-RPSIGDKPCKQEK----- 1211

Query: 1123 PWASLLLPCSACGAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVL 1182
              +SL     + G                       V+ PLL LTW   +  +    +++
Sbjct: 1212 --SSLFQISKSIG-----------------------VLTPLLGLTWGFGLTTVFPGTNLV 1246

Query: 1183 FQALFAVFNSAQGFVITAVHCFLRREVQDVVKCQMGVCR 1221
            F  +FA+ N  QG  I    C    +VQ+ +  +  + R
Sbjct: 1247 FHIIFAILNVFQGLFILLFGCLWDLKVQEALLNKFSLSR 1285


>gi|147904700 semaphorin 5A [Homo sapiens]
          Length = 1074

 Score =  135 bits (340), Expect = 3e-31
 Identities = 65/164 (39%), Positives = 82/164 (50%), Gaps = 10/164 (6%)

Query: 363 VHGVWEEWGSWSLCSRSCGRGSRSRMRTC--VPPQHGGKACEGPELQTKLCSMAACPVEG 420
           V+G W  W SWS CSR C RG R+R R C    P++GG  C GP L+ + C++  CPV+G
Sbjct: 783 VNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPVDG 842

Query: 421 QWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWA--TCTGALTDTRECSNLECPATDSKW 478
            W  W PW  CS +C  G   R+R CS   PA+    C G  T+   C+   CP     W
Sbjct: 843 VWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCP---ESW 899

Query: 479 GPWNAWSLCSKTCDTGWQRRFRMCQATGTQGYPCEGTGEEVKPC 522
             W+ WS C     +G Q R R C      G  C G   E +PC
Sbjct: 900 SEWSDWSECEA---SGVQVRARQCILLFPMGSQCSGNTTESRPC 940



 Score =  134 bits (336), Expect = 9e-31
 Identities = 76/244 (31%), Positives = 100/244 (40%), Gaps = 35/244 (14%)

Query: 315 WSPWSVCSLTCGQGLQVRTRSCVSSPY----GTLCSGPLRETRPCNNSATCPVHGVWEEW 370
           W+ WS CS TCG G QVR RSC S+P     G +C G  RE R CN    CP H  W  W
Sbjct: 601 WTSWSPCSTTCGIGFQVRQRSC-SNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGW 659

Query: 371 GSWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMAACPVEGQWLEWGPWGP 430
           G W  C+  CG G ++R R C      G  C G  ++ + C+   CP   +   W PW P
Sbjct: 660 GPWERCTAQCGGGIQARRRIC----ENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTP 715

Query: 431 CSTSCANGTQQR------------------------SRKCSVAGPAWATCTGALTDTREC 466
            + S   G  ++                         R CS  G +  +  G   D    
Sbjct: 716 VNISDNGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRA 775

Query: 467 SNLECPATDSKWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQ--GYPCEGTGEEVKPCSE 524
                   +  W  W +WS CS+ C  G + R R+C     +  G PC G   E + C+ 
Sbjct: 776 GRYSAHTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNI 835

Query: 525 KRCP 528
             CP
Sbjct: 836 LPCP 839



 Score =  122 bits (305), Expect = 4e-27
 Identities = 65/171 (38%), Positives = 87/171 (50%), Gaps = 11/171 (6%)

Query: 301 GLYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSP--YGTL-CSGPLRETRPCNN 357
           G Y A T + A   W+ WS CS  C +G++ R R C +    YG + C GP  E + CN 
Sbjct: 776 GRYSAHTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECN- 834

Query: 358 SATCPVHGVWEEWGSWSLCSRSCGRGSRSRMRTC--VPPQHGGKACEGPELQTKLCSMAA 415
              CPV GVW  W  W+ CS +CG G   R R+C    P +GG  C G   +  LC+   
Sbjct: 835 ILPCPVDGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQP 894

Query: 416 CPVEGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTREC 466
           CP    W EW  W  C    A+G Q R+R+C +  P  + C+G  T++R C
Sbjct: 895 CP--ESWSEWSDWSECE---ASGVQVRARQCILLFPMGSQCSGNTTESRPC 940



 Score =  119 bits (298), Expect = 2e-26
 Identities = 81/232 (34%), Positives = 108/232 (46%), Gaps = 25/232 (10%)

Query: 285 EEPKVKTQWPRSADE-PGLYMAQTGDPAAEEWSPWSVCSLTCGQGL---QVRTRSCVS-S 339
           EE    TQW +S    P   +   G      WSPW+ C+ T G  +     RTRSC S +
Sbjct: 517 EESLSMTQWEQSISACPTRNLTVDGHFGV--WSPWTPCTHTDGSAVGSCLCRTRSCDSPA 574

Query: 340 PY--GTLCSGPLRETRPCNNSATCPVHGVWEEWGSWSLCSRSCGRGSRSRMRTC--VPPQ 395
           P   G  C GP  E       A C  +G W  W SWS CS +CG G + R R+C    P+
Sbjct: 575 PQCGGWQCEGPGMEI------ANCSRNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPR 628

Query: 396 HGGKACEGPELQTKLCS-MAACPVEGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWA 454
           HGG+ C G   + + C+    CP    W  WGPW  C+  C  G Q R R C   GP   
Sbjct: 629 HGGRVCVGQNREERYCNEHLLCPPHMFWTGWGPWERCTAQCGGGIQARRRICE-NGP--- 684

Query: 455 TCTGALTDTRECSNLECPATDSKWGPWNAWSLCSKTCDTG-WQRRFR-MCQA 504
            C G   + + C+   CP    K  PW  W+  + + + G +++RFR  C+A
Sbjct: 685 DCAGCNVEYQSCNTNPCPEL-KKTTPWTPWTPVNISDNGGHYEQRFRYTCKA 735



 Score = 99.0 bits (245), Expect = 3e-20
 Identities = 62/183 (33%), Positives = 80/183 (43%), Gaps = 23/183 (12%)

Query: 359 ATCP-----VHGVWEEWGSWSLCSRSCGRGSRS---RMRTC--VPPQHGGKACEGPELQT 408
           + CP     V G +  W  W+ C+ + G    S   R R+C    PQ GG  CEGP ++ 
Sbjct: 530 SACPTRNLTVDGHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGME- 588

Query: 409 KLCSMAACPVEGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGP--AWATCTGALTDTREC 466
               +A C   G W  W  W PCST+C  G Q R R CS   P      C G   + R C
Sbjct: 589 ----IANCSRNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYC 644

Query: 467 S-NLECPATDSKWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQGYPCEGTGEEVKPCSEK 525
           + +L CP     W  W  W  C+  C  G Q R R+C+     G  C G   E + C+  
Sbjct: 645 NEHLLCP-PHMFWTGWGPWERCTAQCGGGIQARRRICE----NGPDCAGCNVEYQSCNTN 699

Query: 526 RCP 528
            CP
Sbjct: 700 PCP 702



 Score = 64.7 bits (156), Expect = 7e-10
 Identities = 43/131 (32%), Positives = 56/131 (42%), Gaps = 21/131 (16%)

Query: 412 SMAACP-----VEGQWLEWGPWGPCS---TSCANGTQQRSRKCSVAGP---AWATCTGAL 460
           S++ACP     V+G +  W PW PC+    S       R+R C    P    W  C G  
Sbjct: 528 SISACPTRNLTVDGHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGW-QCEGPG 586

Query: 461 TDTRECSNLECPATDSKWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQ--GYPCEGTGEE 518
            +   CS       +  W PW +WS CS TC  G+Q R R C     +  G  C G   E
Sbjct: 587 MEIANCSR------NGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNRE 640

Query: 519 VKPCSEK-RCP 528
            + C+E   CP
Sbjct: 641 ERYCNEHLLCP 651



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 24/58 (41%), Positives = 29/58 (50%), Gaps = 4/58 (6%)

Query: 299 EPGLYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCV-SSPYGTLCSGPLRETRPC 355
           E  L   Q    +  EWS WS C      G+QVR R C+   P G+ CSG   E+RPC
Sbjct: 886 EEALCNTQPCPESWSEWSDWSECE---ASGVQVRARQCILLFPMGSQCSGNTTESRPC 940


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,023,346
Number of Sequences: 37866
Number of extensions: 4210296
Number of successful extensions: 26872
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 138
Number of HSP's successfully gapped in prelim test: 307
Number of HSP's that attempted gapping in prelim test: 22721
Number of HSP's gapped (non-prelim): 3612
length of query: 1585
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1469
effective length of database: 13,855,062
effective search space: 20353086078
effective search space used: 20353086078
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.